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Gene Dmel\wde

General Information
Symbol	Dmel\wde	Species	D. melanogaster
Name	windei	Annotation symbol	CG12340
Feature type	protein_coding_gene	FlyBase ID	FBgn0027499
Gene Model Status	Current	Stock availability	14 publicly available
Genomic Location
Chromosome (arm)	2R	Recombination map
Cytogenetic map	47C1-47C1	Sequence location	2R:6,687,924..6,696,430 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene windei is referred to in FlyBase by the symbol Dmel\wde (CG12340, FBgn0027499). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 23 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; ovariole. It has one annotated transcript and one annotated polypeptide. Protein features are: Fibronectin, type III; Immunoglobulin-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult salivary gland, larval trachea, adult female reproductive system. Comments on Affy2 ProbeSet: ProbeSet 1626478_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of wde. Gene sequence location is 2R:6687924..6696430.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	Sequence features HFA05955 BKN45170 BKN25069
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 47C1-47C1   Limits computationally determined from genome sequence between P{PZ}lola00349&P{EP}lolaEP952 and P{lacW}l(2)k00909k00909&P{EP}EP2619EP2619
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\wde for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) wde-RA FBtr0088253  NM_136764   4794   1420
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein wde-PA   FBpp0087348   156.8   1420   4.37     NP_610608   AAF58755
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Fibronectin, type III (IPR003961) Immunoglobulin-like fold (IPR013783)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA736002   AA940714   AA942040   AA942090   AE013599 AAF58755   AF145688 AAD38663   AI106838   AI296539   AI515124   AI543899   AW942827   BF485573   BG639197   BP544761   BP544762   BP552057   BQ103170   BZ665525   BZ665574   CK658569   CO271893   CO278763   CO280935   CO317323   CO322310   CO325319   CO343334   CZ467245   CZ474980   CZ474981   CZ475343   CZ478693   CZ480043   CZ480044   CZ482487   CZ482488   CZ486951   CZ490245   CZ490246   EC060147   EC063284   EC073371   EC074679   EC077772   EC077832   EC223871   EC226992   EC231872   EC232548   EC244365   EC250495   EV576119   EV579985
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q7KMH9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Wasbrough et al., 2010)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0027499    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0027499 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0027499 expression level Developmental Stage   Expression Level embryo 00-02hr    2889 embryo 02-04hr    2246 embryo 04-06hr    2697 embryo 06-08hr    2136 embryo 08-10hr    2003 embryo 10-12hr    961 embryo 12-14hr    1454 embryo 14-16hr    1008 embryo 16-18hr    980 embryo 18-20hr    821 embryo 20-22hr    872 embryo 22-24hr    909 larva L1    825 larva L2    484 larva L3 12hr old    427 larva L3 puffstage 1-2    475 larva L3 puffstage 3-6    727 larva L3 puffstage 7-9    936 white prepupae new    1027 white prepupae 12hr    1092 white prepupae 24hr    1306 pupae 2d postWPP    1005 pupae 3d postWPP    616 pupae 4d postWPP    451 adult male 01day    479 adult male 05day    534 adult male 30day    530 adult female 01day    820 adult female 05day    1813 adult female 30day    1774 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2889) embryo 02-04hr  (2246) embryo 04-06hr  (2697) embryo 06-08hr  (2136) embryo 08-10hr  (2003) embryo 10-12hr  (961) embryo 12-14hr  (1454) embryo 14-16hr  (1008) embryo 16-18hr  (980) embryo 18-20hr  (821) embryo 20-22hr  (872) embryo 22-24hr  (909) larva L1  (825) larva L2  (484) larva L3 12hr old  (427) larva L3 puffstage 1-2  (475) larva L3 puffstage 3-6  (727) larva L3 puffstage 7-9  (936) white prepupae new  (1027) white prepupae 12hr  (1092) white prepupae 24hr  (1306) pupae 2d postWPP  (1005) pupae 3d postWPP  (616) pupae 4d postWPP  (451) adult male 01day  (479) adult male 05day  (534) adult male 30day  (530) adult female 01day  (820) adult female 05day  (1813) adult female 30day  (1774) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2889) embryo 02-04hr  (2246) embryo 04-06hr  (2697) embryo 06-08hr  (2136) embryo 08-10hr  (2003) embryo 10-12hr    961 embryo 12-14hr  1454 embryo 14-16hr    1008 embryo 16-18hr    980 embryo 18-20hr    821 embryo 20-22hr    872 embryo 22-24hr    909 larva L1    825 larva L2    484 larva L3 12hr old    427 larva L3 puffstage 1-2    475 larva L3 puffstage 3-6    727 larva L3 puffstage 7-9    936 white prepupae new    1027 white prepupae 12hr    1092 white prepupae 24hr    1306 pupae 2d postWPP    1005 pupae 3d postWPP    616 pupae 4d postWPP    451 adult male 01day    479 adult male 05day    534 adult male 30day    530 adult female 01day    820 adult female 05day  (1813) adult female 30day  (1774) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2889 embryo 02-04hr    2246 embryo 04-06hr    2697 embryo 06-08hr    2136 embryo 08-10hr    2003 embryo 10-12hr    961 embryo 12-14hr    1454 embryo 14-16hr    1008 embryo 16-18hr    980 embryo 18-20hr    821 embryo 20-22hr    872 embryo 22-24hr    909 larva L1    825 larva L2    484 larva L3 12hr old    427 larva L3 puffstage 1-2    475 larva L3 puffstage 3-6    727 larva L3 puffstage 7-9    936 white prepupae new    1027 white prepupae 12hr    1092 white prepupae 24hr    1306 pupae 2d postWPP    1005 pupae 3d postWPP    616 pupae 4d postWPP    451 adult male 01day    479 adult male 05day    534 adult male 30day    530 adult female 01day    820 adult female 05day    1813 adult female 30day    1774 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2889 embryo 02-04hr    2246 embryo 04-06hr    2697 embryo 06-08hr    2136 embryo 08-10hr    2003 embryo 10-12hr    961 embryo 12-14hr    1454 embryo 14-16hr    1008 embryo 16-18hr    980 embryo 18-20hr    821 embryo 20-22hr    872 embryo 22-24hr    909 larva L1    825 larva L2    484 larva L3 12hr old    427 larva L3 puffstage 1-2    475 larva L3 puffstage 3-6    727 larva L3 puffstage 7-9    936 white prepupae new    1027 white prepupae 12hr    1092 white prepupae 24hr    1306 pupae 2d postWPP    1005 pupae 3d postWPP    616 pupae 4d postWPP    451 adult male 01day    479 adult male 05day    534 adult male 30day    530 adult female 01day    820 adult female 05day    1813 adult female 30day    1774 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0027499 expression level Developmental Stage   Expression Level embryo 00-02hr    2889 embryo 02-04hr    2246 embryo 04-06hr    2697 embryo 06-08hr    2136 embryo 08-10hr    2003 embryo 10-12hr    961 embryo 12-14hr    1454 embryo 14-16hr    1008 embryo 16-18hr    980 embryo 18-20hr    821 embryo 20-22hr    872 embryo 22-24hr    909 larva L1    825 larva L2    484 larva L3 12hr old    427 larva L3 puffstage 1-2    475 larva L3 puffstage 3-6    727 larva L3 puffstage 7-9    936 white prepupae new    1027 white prepupae 12hr    1092 white prepupae 24hr    1306 pupae 2d postWPP    1005 pupae 3d postWPP    616 pupae 4d postWPP    451 adult male 01day    479 adult male 05day    534 adult male 30day    530 adult female 01day    820 adult female 05day    1813 adult female 30day    1774 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2889) embryo 02-04hr  (2246) embryo 04-06hr  (2697) embryo 06-08hr  (2136) embryo 08-10hr  (2003) embryo 10-12hr  (961) embryo 12-14hr  (1454) embryo 14-16hr  (1008) embryo 16-18hr  (980) embryo 18-20hr  (821) embryo 20-22hr  (872) embryo 22-24hr  (909) larva L1  (825) larva L2  (484) larva L3 12hr old  (427) larva L3 puffstage 1-2  (475) larva L3 puffstage 3-6  (727) larva L3 puffstage 7-9  (936) white prepupae new  (1027) white prepupae 12hr  (1092) white prepupae 24hr  (1306) pupae 2d postWPP  (1005) pupae 3d postWPP  (616) pupae 4d postWPP  (451) adult male 01day  (479) adult male 05day  (534) adult male 30day  (530) adult female 01day  (820) adult female 05day  (1813) adult female 30day  (1774) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2889) embryo 02-04hr  2246 embryo 04-06hr  (2697) embryo 06-08hr  2136 embryo 08-10hr  2003 embryo 10-12hr    961 embryo 12-14hr  1454 embryo 14-16hr    1008 embryo 16-18hr    980 embryo 18-20hr    821 embryo 20-22hr    872 embryo 22-24hr    909 larva L1    825 larva L2    484 larva L3 12hr old    427 larva L3 puffstage 1-2    475 larva L3 puffstage 3-6    727 larva L3 puffstage 7-9    936 white prepupae new    1027 white prepupae 12hr    1092 white prepupae 24hr    1306 pupae 2d postWPP    1005 pupae 3d postWPP    616 pupae 4d postWPP    451 adult male 01day    479 adult male 05day    534 adult male 30day    530 adult female 01day    820 adult female 05day  1813 adult female 30day  1774 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2889 embryo 02-04hr    2246 embryo 04-06hr    2697 embryo 06-08hr    2136 embryo 08-10hr    2003 embryo 10-12hr    961 embryo 12-14hr    1454 embryo 14-16hr    1008 embryo 16-18hr    980 embryo 18-20hr    821 embryo 20-22hr    872 embryo 22-24hr    909 larva L1    825 larva L2    484 larva L3 12hr old    427 larva L3 puffstage 1-2    475 larva L3 puffstage 3-6    727 larva L3 puffstage 7-9    936 white prepupae new    1027 white prepupae 12hr    1092 white prepupae 24hr    1306 pupae 2d postWPP    1005 pupae 3d postWPP    616 pupae 4d postWPP    451 adult male 01day    479 adult male 05day    534 adult male 30day    530 adult female 01day    820 adult female 05day    1813 adult female 30day    1774 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2889 embryo 02-04hr    2246 embryo 04-06hr    2697 embryo 06-08hr    2136 embryo 08-10hr    2003 embryo 10-12hr    961 embryo 12-14hr    1454 embryo 14-16hr    1008 embryo 16-18hr    980 embryo 18-20hr    821 embryo 20-22hr    872 embryo 22-24hr    909 larva L1    825 larva L2    484 larva L3 12hr old    427 larva L3 puffstage 1-2    475 larva L3 puffstage 3-6    727 larva L3 puffstage 7-9    936 white prepupae new    1027 white prepupae 12hr    1092 white prepupae 24hr    1306 pupae 2d postWPP    1005 pupae 3d postWPP    616 pupae 4d postWPP    451 adult male 01day    479 adult male 05day    534 adult male 30day    530 adult female 01day    820 adult female 05day    1813 adult female 30day    1774 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0027499    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0027499 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult salivary gland, larval trachea, adult female reproductive system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0027499 expression level Tissue   Expression Level Larval Central Nervous System    371.9 Larval Midgut    46.2 Larval Hindgut    62.2 Larval Malpighian Tubules    62.1 Larval Fat Body    55.4 Larval Salivary Gland    98 Larval Trachea    122 Larval Carcass    74.525 Adult Head    99 Adult Eye    68.85 Adult Brain    318.3 Adult Thoracic-Abdominal Ganglion    335.2 Adult Crop    65.1 Adult Midgut no informative data Adult Hindgut    36.7 Adult Malpighian Tubules    56.5 Adult Fat Body    41.8 Adult Salivary Gland    120 Adult Heart    42.4 Adult VirginFemale Spermatheca    86.6 Adult InseminatedFemale Spermatheca    105.9 Adult Ovary    257.9 Adult Testis    60.8 Adult Male Accessory Gland    85.1 Adult Carcass    49.8 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    371.9 Larval Midgut    46.2 Larval Hindgut    62.2 Larval Malpighian Tubules    62.1 Larval Fat Body    55.4 Larval Salivary Gland    98 Larval Trachea    122 Larval Carcass    74.525 Adult Head    99 Adult Eye    68.85 Adult Brain    318.3 Adult Thoracic-Abdominal Ganglion    335.2 Adult Crop    65.1 Adult Midgut no informative data Adult Hindgut    36.7 Adult Malpighian Tubules    56.5 Adult Fat Body    41.8 Adult Salivary Gland    120 Adult Heart    42.4 Adult VirginFemale Spermatheca    86.6 Adult InseminatedFemale Spermatheca    105.9 Adult Ovary    257.9 Adult Testis    60.8 Adult Male Accessory Gland    85.1 Adult Carcass    49.8 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    371.9 Larval Midgut    46.2 Larval Hindgut    62.2 Larval Malpighian Tubules    62.1 Larval Fat Body    55.4 Larval Salivary Gland    98 Larval Trachea    122 Larval Carcass    74.525 Adult Head    99 Adult Eye    68.85 Adult Brain    318.3 Adult Thoracic-Abdominal Ganglion    335.2 Adult Crop    65.1 Adult Midgut no informative data Adult Hindgut    36.7 Adult Malpighian Tubules    56.5 Adult Fat Body    41.8 Adult Salivary Gland    120 Adult Heart    42.4 Adult VirginFemale Spermatheca    86.6 Adult InseminatedFemale Spermatheca    105.9 Adult Ovary    257.9 Adult Testis    60.8 Adult Male Accessory Gland    85.1 Adult Carcass    49.8 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    371.9 Larval Midgut    46.2 Larval Hindgut    62.2 Larval Malpighian Tubules    62.1 Larval Fat Body    55.4 Larval Salivary Gland    98 Larval Trachea    122 Larval Carcass    74.525 Adult Head    99 Adult Eye    68.85 Adult Brain    318.3 Adult Thoracic-Abdominal Ganglion    335.2 Adult Crop    65.1 Adult Midgut no informative data Adult Hindgut    36.7 Adult Malpighian Tubules    56.5 Adult Fat Body    41.8 Adult Salivary Gland    120 Adult Heart    42.4 Adult VirginFemale Spermatheca    86.6 Adult InseminatedFemale Spermatheca    105.9 Adult Ovary    257.9 Adult Testis    60.8 Adult Male Accessory Gland    85.1 Adult Carcass    49.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0027499 expression level Tissue   Expression Level Larval Central Nervous System    371.9 Larval Midgut    46.2 Larval Hindgut    62.2 Larval Malpighian Tubules    62.1 Larval Fat Body    55.4 Larval Salivary Gland    98 Larval Trachea    122 Larval Carcass    74.525 Adult Head    99 Adult Eye    68.85 Adult Brain    318.3 Adult Thoracic-Abdominal Ganglion    335.2 Adult Crop    65.1 Adult Midgut no informative data Adult Hindgut    36.7 Adult Malpighian Tubules    56.5 Adult Fat Body    41.8 Adult Salivary Gland    120 Adult Heart    42.4 Adult VirginFemale Spermatheca    86.6 Adult InseminatedFemale Spermatheca    105.9 Adult Ovary    257.9 Adult Testis    60.8 Adult Male Accessory Gland    85.1 Adult Carcass    49.8 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    371.9 Larval Midgut    46.2 Larval Hindgut    62.2 Larval Malpighian Tubules    62.1 Larval Fat Body    55.4 Larval Salivary Gland    98 Larval Trachea    122 Larval Carcass    74.525 Adult Head    99 Adult Eye    68.85 Adult Brain    318.3 Adult Thoracic-Abdominal Ganglion    335.2 Adult Crop    65.1 Adult Midgut no informative data Adult Hindgut    36.7 Adult Malpighian Tubules    56.5 Adult Fat Body    41.8 Adult Salivary Gland    120 Adult Heart    42.4 Adult VirginFemale Spermatheca    86.6 Adult InseminatedFemale Spermatheca    105.9 Adult Ovary    257.9 Adult Testis    60.8 Adult Male Accessory Gland    85.1 Adult Carcass    49.8 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    371.9 Larval Midgut    46.2 Larval Hindgut    62.2 Larval Malpighian Tubules    62.1 Larval Fat Body    55.4 Larval Salivary Gland    98 Larval Trachea    122 Larval Carcass    74.525 Adult Head    99 Adult Eye    68.85 Adult Brain    318.3 Adult Thoracic-Abdominal Ganglion    335.2 Adult Crop    65.1 Adult Midgut no informative data Adult Hindgut    36.7 Adult Malpighian Tubules    56.5 Adult Fat Body    41.8 Adult Salivary Gland    120 Adult Heart    42.4 Adult VirginFemale Spermatheca    86.6 Adult InseminatedFemale Spermatheca    105.9 Adult Ovary    257.9 Adult Testis    60.8 Adult Male Accessory Gland    85.1 Adult Carcass    49.8 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    371.9 Larval Midgut    46.2 Larval Hindgut    62.2 Larval Malpighian Tubules    62.1 Larval Fat Body    55.4 Larval Salivary Gland    98 Larval Trachea    122 Larval Carcass    74.525 Adult Head    99 Adult Eye    68.85 Adult Brain    318.3 Adult Thoracic-Abdominal Ganglion    335.2 Adult Crop    65.1 Adult Midgut no informative data Adult Hindgut    36.7 Adult Malpighian Tubules    56.5 Adult Fat Body    41.8 Adult Salivary Gland    120 Adult Heart    42.4 Adult VirginFemale Spermatheca    86.6 Adult InseminatedFemale Spermatheca    105.9 Adult Ovary    257.9 Adult Testis    60.8 Adult Male Accessory Gland    85.1 Adult Carcass    49.8 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut no informative data Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    99   NA  Eye    68.85   NA  Brain    318.3   371.9  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    335.2   NA  Crop    65.1   46.2  Midgut    no informative data   62.2  Hindgut    36.7   62.1  Malpighian Tubules    56.5   55.4  Fat Body    41.8   98  Salivary Gland    120   NA  Heart    42.4   122  Trachea    NA   NA  VirginFemale Spermatheca    86.6   NA  InseminatedFemale Spermatheca    105.9   NA  Ovary    257.9   NA  Testis    60.8   NA  Male Accessory Gland    85.1   74.525  Carcass    49.8 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_17
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0027499 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12340-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | P-stage (with wded06198) wdeEY00884 wdeTD63 lethal | P-stage (with wdeEY00884) wded06198 wdeTD63 lethal | P-stage (with wdeTD63) wded06198 wdeEY00884 lethal | P-stage | recessive wded06198 wdeEY00884 wdeTD63 viable, with Scer\GAL4pnr-MD237 wdeGD12648 Sterility Allele female sterile | germline clone | recessive wded06198 wdeTD63 female sterile | recessive wdeEY00884 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 wdeGD12648 Phenotype manifest in Allele oocyte | germline clone wded06198 wdeTD63 ovariole wdeEY00884 trichogen cell, with Scer\GAL4pnr-MD237 wdeGD12648
Classical Alleles ( 19 )
For All Classical Alleles Show
Allele of wde Class Mutagen Stocks Known lesion wdec01550 piggyBac transposase 1 -- wded06198 P-element activity 1 -- wded06774 P-element activity 1 -- wdeDG08703 1 -- wdee00851 piggyBac transposase 1 -- wdeEY00884 P-element activity 1 -- wdef00002 piggyBac transposase 1 -- wdeMI02099 1 -- wdeNP2308 1 -- wdeNP6337 1 -- wdee02219 piggyBac transposase 0 -- wdeEP2024 0 -- wdeEY02179 P-element activity 0 -- wdef04413 piggyBac transposase 0 -- wdef07507 piggyBac transposase 0 -- wdeGS-A2450 Delta2-3 0 -- wdeNP4259 0 -- wdeSH2196 0 -- wdeTD63 FLPase 0 Yes
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of wde Class Mutagen Stocks Known lesion wdeGD12648 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes wdeHMS00205 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes wdeKK104109 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes wdeScer\UAS.P\T.T:Avic\GFP in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2R)Exel7112 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{TRiP.HMS00205} NA P{UASp-wde.GFP} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}wdeEP2024 NA P{EPgy2}wdeEY00884 NA P{EPgy2}wdeEY02179 NA P{GSV1}wdeGS-A2450 NA P{XP}wded06198 NA P{XP}wded06774 NA miscellaneous insertions Mi{MIC}wdeMI02099 NA P{wHy}wdeDG08703 NA PBac{PB}wdec01550 NA PBac{RB}wdee00851 NA PBac{RB}wdee02219 NA PBac{WH}wdef00002 NA PBac{WH}wdef04413 NA PBac{WH}wdef07507 NA insertion of enhancer trap P{lacW}l(2)SH1918SH1918 No P{lacW}wdeSH2196 No insertion of enhancer trap binary system P{GawB}wdeNP2308 No P{GawB}wdeNP4259 No P{GawB}wdeNP6337 No
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
chromosome inferred from direct assay (Koch et al., 2009)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions wde allele Gene References unspecified ct (Krupp et al., 2005)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 61941 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0027499 DroID - A comprehensive database of gene and protein interactions. • FBgn0027499 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36133
Orthologs
Genome-wide drosophilid orthologs	Dana\GF11088 Dere\GG22720 Dgri\GH23846 Dmoj\GI19168 Dpse\GA25025 Dsec\GM20495 Dsim\GD25958 Dvir\GJ20126 Dwil\GK19658 Dyak\GE13076
Curated drosophilid orthologs	Dpse\GA11565   Dsim\CG12340 (Swanson et al., 2001)
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL007417-PA Aedes aegypti (mosquito) AGAP005147-PA Anopheles gambiae (mosquito) XP_001946068.1 Acyrthosiphon pisum (pea aphid) BGIBMGA011611-PA Bombyx mori (silk worm) ENSBTAP00000004182 Bos taurus (bovine) ENSCAFP00000019333 Canis familiaris (dog) CPIJ018836 Culex pipens (mosquito) ENSCPOP00000013495 Cavia porcellus (guinea pig) 247447 Daphnia pulex (daphnia) ENSECAP00000006261 Equus caballus (horse) ENSGALP00000019263 Gallus gallus (chicken) 163488 Hypsipyla robusta (cedar shoot borer) ENSP00000261168 Homo sapiens (human) ENSMMUP00000016651 Macaca mulatta (rhesus monkey) ENSMUSP00000032335 Mus musculus (house mouse) PHUM006299-PA Pediculus humanus (human body louse) ENSPPYP00000004931 Pongo pygmaeus (orangutan) ENSPTRP00000008061 Pan troglodytes (chimpanzee) ENSRNOP00000052561 Rattus norvegicus (norway rat) ENSTNIP00000009962 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000000063 Takifugu rubripes (pufferfish Takifugu) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0230780 FBgn0221656 FBgn0197235 FBgn0175377 FBgn0246408 FBgn0154784 FBgn0130985 FBgn0114885 FBgn0088128 AGAP005147 AAEL007417
Stocks & Reagents
Stocks Listed in FlyBase ( 14 )
Bloomington	21669 y1 w67c23; P{wHy}wdeDG08703 34274 y1 w*; Mi{MIC}wdeMI02099/SM6a 33339 y1 sc* v1; P{TRiP.HMS00205}attP2
Harvard	- P{XP}wded06198 - P{XP}wded06774 - PBac{PB}wdec01550 - PBac{RB}wdee00851 - PBac{WH}wdef00002
Kyoto	112875 w*; P{GawB}wdeNP2308 / CyO
VDRC	v105719 P{KK104109}VIE-260B v22878 w1118; P{GD12648}v22878 v23606 w1118; P{GD12648}v23606
	More stocks available...
Genomic Clones ( 2 )
	BACR08L17 BACR13J10 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 35 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD26050
Other clones	DPiM_LD26050
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT19613 GH06075 GM10269 LD22857 LD26128 LD45575 LP10482 LP15582
Other clones	150 11919 15614 41811 64711 65445 67293 157237 158640 163519 177514 CK01.131B.E6 Dmel_dig_005209_0672_3748 Dmel_dig_006186_0605_3624 EK105050 EK131512 EK155521 EK187852 EK196116 EK267662 EP16609 FGC027F06 FGM216D11 LD46822 UUGC0568
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0027499 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36133
Antibody Information
	polyclonal (Koch et al., 2009)
Other Information
Discoverer
Etymology
	Named "windei" (german for wind egg) after the phenotype of its loss-of-function alleles . (Koch et al., 2009)
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	FlyBase curator comment: Correspondence with author Koch revealed that 'Wde' = 'CG12340'. (Koch et al., 2008)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_136764 RefSeq (Proteins) • NP_610608 DDBJ / EMBL / GenBank • AA942040 AAD38663 AAF58755 AF145688 AW942827 BZ665525 BZ665574 CZ467245 CZ474980 CZ474981 CZ475343 CZ478693 CZ480043 CZ480044 CZ482487 CZ482488 CZ486951 CZ490245 CZ490246 Entrez Gene - A searchable database of RefSeq genes. • 36133 UniProtKB/TrEMBL • Q7KMH9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Fibronectin, type III (IPR003961) Immunoglobulin-like fold (IPR013783)
Linkouts
	BioGRID - A database of protein and genetic interactions • 61941 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0027499 DroID - A comprehensive database of gene and protein interactions. • FBgn0027499 DRSC - Results from RNAi screens. • FBgn0027499 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0027499 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG12340-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0027499 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 36133 InParanoid A subset of ortholog calls from InParanoid. • AAEL007417-PA Aedes aegypti (mosquito) AGAP005147-PA Anopheles gambiae (mosquito) XP_001946068.1 Acyrthosiphon pisum (pea aphid) BGIBMGA011611-PA Bombyx mori (silk worm) ENSBTAP00000004182 Bos taurus (bovine) ENSCAFP00000019333 Canis familiaris (dog) CPIJ018836 Culex pipens (mosquito) ENSCPOP00000013495 Cavia porcellus (guinea pig) 247447 Daphnia pulex (daphnia) ENSECAP00000006261 Equus caballus (horse) ENSGALP00000019263 Gallus gallus (chicken) 163488 Hypsipyla robusta (cedar shoot borer) ENSP00000261168 Homo sapiens (human) ENSMMUP00000016651 Macaca mulatta (rhesus monkey) ENSMUSP00000032335 Mus musculus (house mouse) PHUM006299-PA Pediculus humanus (human body louse) ENSPPYP00000004931 Pongo pygmaeus (orangutan) ENSPTRP00000008061 Pan troglodytes (chimpanzee) ENSRNOP00000052561 Rattus norvegicus (norway rat) ENSTNIP00000009962 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000000063 Takifugu rubripes (pufferfish Takifugu) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 36133 modMine - Data generated by the modENCODE project. • FBgn0027499 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0230780 FBgn0221656 FBgn0197235 FBgn0175377 FBgn0246408 FBgn0154784 FBgn0130985 FBgn0114885 FBgn0088128 AGAP005147 AAEL007417
Synonyms & Secondary IDs ( 9 )
Reported As
Symbol Synonym	BcDNA:LD26050 (Giot et al., 2003, ) CG12340 (Koch et al., 2009, FlyBase Curators, 2008, Keleman et al., 2009.8.5, Ni et al., 2010.12.1) i10 (Battersby et al., 2003) i119 (Battersby et al., 2003) LD26050 (Battersby et al., 2003) Wde (Koch et al., 2008) wde (Koch et al., 2009, Wasbrough et al., 2010)
Name Synonym	Windei (Koch et al., 2008) windei (Koch et al., 2009)
Secondary FlyBase IDs
References ( 21 )
Generate a list of	All references relating to this gene ( 21 )
List References by type	Research paper  ( 3 ) Supplementary material  ( 6 ) Personal communication to FlyBase  ( 5 ) Abstract  ( 1 ) FlyBase analysis  ( 2 ) Computer file  ( 3 ) Automatic genome annotation  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2010 Show research papers ...