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Gene Dmel\CG7115

General Information
Symbol	Dmel\CG7115	Species	D. melanogaster
Name		Annotation symbol	CG7115
Feature type	protein_coding_gene	FlyBase ID	FBgn0027515
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	28D1-28D1	Sequence location	2L:7,821,151..7,825,350 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG7115 (FBgn0027515). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: protein serine/threonine phosphatase activity. There is experimental evidence that it is involved in the biological process: regulation of cell shape; cell adhesion. 6 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Protein phosphatase 2C; Protein phosphatase 2C (PP2C)-like; Protein phosphatase 2C, manganese/magnesium aspartate binding site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult ovary, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male reproductive system, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1633918_s_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG7115. Gene sequence location is 2L:7821151..7825350.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 28D1-28D1   Limits computationally determined from genome sequence between P{EP}EP2178 and P{PZ}mts02496
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG7115 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.44 Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG7115-RA FBtr0079523  NM_164774   2646   524 CG7115-RB FBtr0079524  NM_135310   2238   524 CG7115-RC FBtr0331234  NM_001273285   1995   469 CG7115-RD FBtr0331235  NM_001273286   2001   471 CG7115-RE FBtr0331236  NM_001273287   2612   524
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG7115-PA   FBpp0079146   58.0   524   9.23     NP_723320   AAF52564 CG7115-PB   FBpp0079147   58.0   524   9.23     NP_609154   AAF52565 CG7115-PC   FBpp0303676   51.7   469   9.78     NP_001260214   AGB92750 CG7115-PD   FBpp0303677   51.9   471   9.78     NP_001260215   AGB92751 CG7115-PE   FBpp0303678   58.0   524   9.23     NP_001260216   AGB92752
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Protein phosphatase 2C, manganese/magnesium aspartate binding site (IPR000222) Protein phosphatase 2C (PP2C)-like (IPR001932) Protein phosphatase 2C (IPR015655)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA392312   AA567936   AA816936   AA950507   AE014134 AAF52564   AE014134 AAF52565   AF132185 AAD34773   AE014134 AGB92750   AE014134 AGB92751   AE014134 AGB92752   AI064006   AI107549   AI455214   AI513758   AI515467   AI945687   BF486307   BF498890   BF506340   BH840514   BI162472   BI162473   BI164548   BI167819   BI169385   BI169673   BI239103   BI356815   BI374424   BI483797   BT125041   CO263748   CO267643   CO270842   CO274187   CO276612   CO276767   CO280244   CO283526   CO293663   CO302293   CO304330   CO323229   CZ470276   EC051104   EC051124   EC052628   EC054108   EC055687   EC056165   EC060170   EC064087   EC071656   EC083103   EC084425   EC086731   EC208357   EC210412   EC210688   EC211666   EC213981   EC232585   EC245090   EC248508   EV577987   EV587256   GH748631   GH752444   GH755983   GH757598   GH757792   GH758481   GH760132   GH773734   GH775324   GH777150   GH777617   GH778799   GH782346   GH783083   GH783679   GH785004   GH786844   GH789911   GH790010   GH792205   GH794006   GH794245   GH794414   GH794800   GH794829   GH795031   GH795715   GH796186   GH797435   GH798312   GH799022   GH799619   GH800534   GH801115   GH801767   GH802788   GH803325   GH804101   GH804315   GH806883   GH810516   GH813946   GH814055   GH816568   GH820776   GH821553   GH822416   GH827278   GH829239   GH833774   GH833851   GH834667   GH836841   GH837214   GH838130   GH839699   GH844824   GH845576   GH847621   GH848330   GH850436   GH852581   GH856530   GH858448   GH861313   GH863500   GH864538   GH868716   GH873356   GH878898   GH880719   GH882707   GH883741   GH893649   GH895500   GH901684   GH902148   GH903728   GH911090   GH911627   GH914720   GH918693   GH919086   GH921875   GH923915   GH927920   GH929507   GH931303   GH935445   GH936817   GH937788   GH940385   GH940972
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9XZ28
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   pole plasm   (Fisher et al., 2012) Comment:maternally deposited organism   • pole plasm (Fisher et al., 2012) Comment:maternally deposited organism   (Fisher et al., 2012) Comment:localized embryonic stage 4 -- 6   pole cell   (Fisher et al., 2012) embryonic stage 7 -- 8   pole cell   (Fisher et al., 2012) embryonic stage 9 -- 10   germline cell   (Fisher et al., 2012) embryonic stage 11 -- 12   germline cell   (Fisher et al., 2012) embryonic stage 13 -- 16   embryonic/larval muscle system   (Fisher et al., 2012) germline cell   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Dorus et al., 2006)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult ovary, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male reproductive system, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    209.225 Larval Midgut    106 Larval Hindgut    208.1 Larval Malpighian Tubules    243.7 Larval Fat Body    278.4 Larval Salivary Gland    102.7 Larval Trachea    126.3 Larval Carcass    585.3 Adult Head    242.2 Adult Eye    163.175 Adult Brain    226.6 Adult Thoracic-Abdominal Ganglion    249 Adult Crop    321 Adult Midgut    105.2 Adult Hindgut    213.8 Adult Malpighian Tubules    272.6 Adult Fat Body    102.2 Adult Salivary Gland    135.1 Adult Heart    464.325 Adult VirginFemale Spermatheca    122 Adult InseminatedFemale Spermatheca    135.2 Adult Ovary    561.7 Adult Testis    266 Adult Male Accessory Gland    139.7 Adult Carcass    440.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    209.225 Larval Midgut    106 Larval Hindgut    208.1 Larval Malpighian Tubules    243.7 Larval Fat Body    278.4 Larval Salivary Gland    102.7 Larval Trachea    126.3 Larval Carcass  (585.3) Adult Head    242.2 Adult Eye    163.175 Adult Brain    226.6 Adult Thoracic-Abdominal Ganglion    249 Adult Crop    321 Adult Midgut    105.2 Adult Hindgut    213.8 Adult Malpighian Tubules    272.6 Adult Fat Body    102.2 Adult Salivary Gland    135.1 Adult Heart    464.325 Adult VirginFemale Spermatheca    122 Adult InseminatedFemale Spermatheca    135.2 Adult Ovary  (561.7) Adult Testis    266 Adult Male Accessory Gland    139.7 Adult Carcass    440.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    209.225 Larval Midgut    106 Larval Hindgut    208.1 Larval Malpighian Tubules    243.7 Larval Fat Body    278.4 Larval Salivary Gland    102.7 Larval Trachea    126.3 Larval Carcass    585.3 Adult Head    242.2 Adult Eye    163.175 Adult Brain    226.6 Adult Thoracic-Abdominal Ganglion    249 Adult Crop    321 Adult Midgut    105.2 Adult Hindgut    213.8 Adult Malpighian Tubules    272.6 Adult Fat Body    102.2 Adult Salivary Gland    135.1 Adult Heart    464.325 Adult VirginFemale Spermatheca    122 Adult InseminatedFemale Spermatheca    135.2 Adult Ovary    561.7 Adult Testis    266 Adult Male Accessory Gland    139.7 Adult Carcass    440.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    209.225 Larval Midgut    106 Larval Hindgut    208.1 Larval Malpighian Tubules    243.7 Larval Fat Body    278.4 Larval Salivary Gland    102.7 Larval Trachea    126.3 Larval Carcass    585.3 Adult Head    242.2 Adult Eye    163.175 Adult Brain    226.6 Adult Thoracic-Abdominal Ganglion    249 Adult Crop    321 Adult Midgut    105.2 Adult Hindgut    213.8 Adult Malpighian Tubules    272.6 Adult Fat Body    102.2 Adult Salivary Gland    135.1 Adult Heart    464.325 Adult VirginFemale Spermatheca    122 Adult InseminatedFemale Spermatheca    135.2 Adult Ovary    561.7 Adult Testis    266 Adult Male Accessory Gland    139.7 Adult Carcass    440.5 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    209.225 Larval Midgut    106 Larval Hindgut    208.1 Larval Malpighian Tubules    243.7 Larval Fat Body    278.4 Larval Salivary Gland    102.7 Larval Trachea    126.3 Larval Carcass    585.3 Adult Head    242.2 Adult Eye    163.175 Adult Brain    226.6 Adult Thoracic-Abdominal Ganglion    249 Adult Crop    321 Adult Midgut    105.2 Adult Hindgut    213.8 Adult Malpighian Tubules    272.6 Adult Fat Body    102.2 Adult Salivary Gland    135.1 Adult Heart    464.325 Adult VirginFemale Spermatheca    122 Adult InseminatedFemale Spermatheca    135.2 Adult Ovary    561.7 Adult Testis    266 Adult Male Accessory Gland    139.7 Adult Carcass    440.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    209.225 Larval Midgut    106 Larval Hindgut    208.1 Larval Malpighian Tubules    243.7 Larval Fat Body    278.4 Larval Salivary Gland    102.7 Larval Trachea    126.3 Larval Carcass  585.3 Adult Head    242.2 Adult Eye    163.175 Adult Brain    226.6 Adult Thoracic-Abdominal Ganglion    249 Adult Crop    321 Adult Midgut    105.2 Adult Hindgut    213.8 Adult Malpighian Tubules    272.6 Adult Fat Body    102.2 Adult Salivary Gland    135.1 Adult Heart    464.325 Adult VirginFemale Spermatheca    122 Adult InseminatedFemale Spermatheca    135.2 Adult Ovary  561.7 Adult Testis    266 Adult Male Accessory Gland    139.7 Adult Carcass    440.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    209.225 Larval Midgut    106 Larval Hindgut    208.1 Larval Malpighian Tubules    243.7 Larval Fat Body    278.4 Larval Salivary Gland    102.7 Larval Trachea    126.3 Larval Carcass    585.3 Adult Head    242.2 Adult Eye    163.175 Adult Brain    226.6 Adult Thoracic-Abdominal Ganglion    249 Adult Crop    321 Adult Midgut    105.2 Adult Hindgut    213.8 Adult Malpighian Tubules    272.6 Adult Fat Body    102.2 Adult Salivary Gland    135.1 Adult Heart    464.325 Adult VirginFemale Spermatheca    122 Adult InseminatedFemale Spermatheca    135.2 Adult Ovary    561.7 Adult Testis    266 Adult Male Accessory Gland    139.7 Adult Carcass    440.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    209.225 Larval Midgut    106 Larval Hindgut    208.1 Larval Malpighian Tubules    243.7 Larval Fat Body    278.4 Larval Salivary Gland    102.7 Larval Trachea    126.3 Larval Carcass    585.3 Adult Head    242.2 Adult Eye    163.175 Adult Brain    226.6 Adult Thoracic-Abdominal Ganglion    249 Adult Crop    321 Adult Midgut    105.2 Adult Hindgut    213.8 Adult Malpighian Tubules    272.6 Adult Fat Body    102.2 Adult Salivary Gland    135.1 Adult Heart    464.325 Adult VirginFemale Spermatheca    122 Adult InseminatedFemale Spermatheca    135.2 Adult Ovary    561.7 Adult Testis    266 Adult Male Accessory Gland    139.7 Adult Carcass    440.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    242.2   NA  Eye    163.175   NA  Brain    226.6   209.225  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    249   NA  Crop    321   106  Midgut    105.2   208.1  Hindgut    213.8   243.7  Malpighian Tubules    272.6   278.4  Fat Body    102.2   102.7  Salivary Gland    135.1   NA  Heart    464.325   126.3  Trachea    NA   NA  VirginFemale Spermatheca    122   NA  InseminatedFemale Spermatheca    135.2   NA  Ovary    561.7   NA  Testis    266   NA  Male Accessory Gland    139.7   585.3  Carcass    440.5 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    29 central nervous system, larvae L3    16 central nervous system, pupae P8    18 head, virgin 1-day female    15 head, virgin 4-day female    13 head, virgin 20-day female    13 head, mated 1-day female    14 head, mated 4-day female    22 head, mated 20-day female    12 head, mated 1-day male    18 head, mated 4-day male    22 head, mated 20-day male    22 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae    27 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    5 digestive system, 4-day adult    8 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    17 fat body, pupae P8    9 carcass, larvae L3 wandering    65 carcass, 1-day adult    22 carcass, 4-day adult    24 carcass, 20-day adult    21 ovary, virgin 4-day female    64 ovary, mated 4-day female    61 testis, mated 4-day male    40 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (29) central nervous system, larvae L3    16 central nervous system, pupae P8    18 head, virgin 1-day female    15 head, virgin 4-day female    13 head, virgin 20-day female    13 head, mated 1-day female    14 head, mated 4-day female    22 head, mated 20-day female    12 head, mated 1-day male    18 head, mated 4-day male    22 head, mated 20-day male    22 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae  (27) digestive system, larvae L3 wandering    12 digestive system, 1-day adult    5 digestive system, 4-day adult    8 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    17 fat body, pupae P8    9 carcass, larvae L3 wandering  (65) carcass, 1-day adult    22 carcass, 4-day adult    24 carcass, 20-day adult    21 ovary, virgin 4-day female  (64) ovary, mated 4-day female  (61) testis, mated 4-day male  (40) accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    29 central nervous system, larvae L3    16 central nervous system, pupae P8    18 head, virgin 1-day female    15 head, virgin 4-day female    13 head, virgin 20-day female    13 head, mated 1-day female    14 head, mated 4-day female    22 head, mated 20-day female    12 head, mated 1-day male    18 head, mated 4-day male    22 head, mated 20-day male    22 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae    27 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    5 digestive system, 4-day adult    8 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    17 fat body, pupae P8    9 carcass, larvae L3 wandering    65 carcass, 1-day adult    22 carcass, 4-day adult    24 carcass, 20-day adult    21 ovary, virgin 4-day female    64 ovary, mated 4-day female    61 testis, mated 4-day male    40 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    29 central nervous system, larvae L3    16 central nervous system, pupae P8    18 head, virgin 1-day female    15 head, virgin 4-day female    13 head, virgin 20-day female    13 head, mated 1-day female    14 head, mated 4-day female    22 head, mated 20-day female    12 head, mated 1-day male    18 head, mated 4-day male    22 head, mated 20-day male    22 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae    27 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    5 digestive system, 4-day adult    8 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    17 fat body, pupae P8    9 carcass, larvae L3 wandering    65 carcass, 1-day adult    22 carcass, 4-day adult    24 carcass, 20-day adult    21 ovary, virgin 4-day female    64 ovary, mated 4-day female    61 testis, mated 4-day male    40 accessory gland, mated 4-day male    11 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    29 central nervous system, larvae L3    16 central nervous system, pupae P8    18 head, virgin 1-day female    15 head, virgin 4-day female    13 head, virgin 20-day female    13 head, mated 1-day female    14 head, mated 4-day female    22 head, mated 20-day female    12 head, mated 1-day male    18 head, mated 4-day male    22 head, mated 20-day male    22 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae    27 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    5 digestive system, 4-day adult    8 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    17 fat body, pupae P8    9 carcass, larvae L3 wandering    65 carcass, 1-day adult    22 carcass, 4-day adult    24 carcass, 20-day adult    21 ovary, virgin 4-day female    64 ovary, mated 4-day female    61 testis, mated 4-day male    40 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  29 central nervous system, larvae L3    16 central nervous system, pupae P8    18 head, virgin 1-day female    15 head, virgin 4-day female    13 head, virgin 20-day female    13 head, mated 1-day female    14 head, mated 4-day female    22 head, mated 20-day female    12 head, mated 1-day male    18 head, mated 4-day male    22 head, mated 20-day male    22 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae  27 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    5 digestive system, 4-day adult    8 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    17 fat body, pupae P8    9 carcass, larvae L3 wandering  (65) carcass, 1-day adult    22 carcass, 4-day adult    24 carcass, 20-day adult    21 ovary, virgin 4-day female  (64) ovary, mated 4-day female  (61) testis, mated 4-day male  (40) accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    29 central nervous system, larvae L3    16 central nervous system, pupae P8    18 head, virgin 1-day female    15 head, virgin 4-day female    13 head, virgin 20-day female    13 head, mated 1-day female    14 head, mated 4-day female    22 head, mated 20-day female    12 head, mated 1-day male    18 head, mated 4-day male    22 head, mated 20-day male    22 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae    27 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    5 digestive system, 4-day adult    8 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    17 fat body, pupae P8    9 carcass, larvae L3 wandering    65 carcass, 1-day adult    22 carcass, 4-day adult    24 carcass, 20-day adult    21 ovary, virgin 4-day female    64 ovary, mated 4-day female    61 testis, mated 4-day male    40 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    29 central nervous system, larvae L3    16 central nervous system, pupae P8    18 head, virgin 1-day female    15 head, virgin 4-day female    13 head, virgin 20-day female    13 head, mated 1-day female    14 head, mated 4-day female    22 head, mated 20-day female    12 head, mated 1-day male    18 head, mated 4-day male    22 head, mated 20-day male    22 salivary gland, larvae L3 wandering    15 salivary gland, white prepupae    27 digestive system, larvae L3 wandering    12 digestive system, 1-day adult    5 digestive system, 4-day adult    8 digestive system, 20-day adult    5 fat body, larvae L3 wandering    4 fat body, white prepupae    17 fat body, pupae P8    9 carcass, larvae L3 wandering    65 carcass, 1-day adult    22 carcass, 4-day adult    24 carcass, 20-day adult    21 ovary, virgin 4-day female    64 ovary, mated 4-day female    61 testis, mated 4-day male    40 accessory gland, mated 4-day male    11 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    58 embryo 02-04hr    26 embryo 04-06hr    12 embryo 06-08hr    11 embryo 08-10hr    14 embryo 10-12hr    19 embryo 12-14hr    17 embryo 14-16hr    20 embryo 16-18hr    30 embryo 18-20hr    19 embryo 20-22hr    9 embryo 22-24hr    11 larva L1    9 larva L2    10 larva L3 12hr old    11 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    50 white prepupae new    97 white prepupae 12hr    25 white prepupae 24hr    22 pupae 2d postWPP    31 pupae 3d postWPP    47 pupae 4d postWPP    18 adult male 01day    31 adult male 05day    34 adult male 30day    27 adult female 01day    24 adult female 05day    39 adult female 30day    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (58) embryo 02-04hr  26 embryo 04-06hr    12 embryo 06-08hr    11 embryo 08-10hr    14 embryo 10-12hr    19 embryo 12-14hr    17 embryo 14-16hr    20 embryo 16-18hr  (30) embryo 18-20hr    19 embryo 20-22hr    9 embryo 22-24hr    11 larva L1    9 larva L2    10 larva L3 12hr old    11 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9  (50) white prepupae new  (97) white prepupae 12hr    25 white prepupae 24hr    22 pupae 2d postWPP  (31) pupae 3d postWPP  (47) pupae 4d postWPP    18 adult male 01day  (31) adult male 05day  (34) adult male 30day  (27) adult female 01day    24 adult female 05day  (39) adult female 30day  (40) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    58 embryo 02-04hr    26 embryo 04-06hr    12 embryo 06-08hr    11 embryo 08-10hr    14 embryo 10-12hr    19 embryo 12-14hr    17 embryo 14-16hr    20 embryo 16-18hr    30 embryo 18-20hr    19 embryo 20-22hr    9 embryo 22-24hr    11 larva L1    9 larva L2    10 larva L3 12hr old    11 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    50 white prepupae new    97 white prepupae 12hr    25 white prepupae 24hr    22 pupae 2d postWPP    31 pupae 3d postWPP    47 pupae 4d postWPP    18 adult male 01day    31 adult male 05day    34 adult male 30day    27 adult female 01day    24 adult female 05day    39 adult female 30day    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    58 embryo 02-04hr    26 embryo 04-06hr    12 embryo 06-08hr    11 embryo 08-10hr    14 embryo 10-12hr    19 embryo 12-14hr    17 embryo 14-16hr    20 embryo 16-18hr    30 embryo 18-20hr    19 embryo 20-22hr    9 embryo 22-24hr    11 larva L1    9 larva L2    10 larva L3 12hr old    11 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    50 white prepupae new    97 white prepupae 12hr    25 white prepupae 24hr    22 pupae 2d postWPP    31 pupae 3d postWPP    47 pupae 4d postWPP    18 adult male 01day    31 adult male 05day    34 adult male 30day    27 adult female 01day    24 adult female 05day    39 adult female 30day    40 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    58 embryo 02-04hr    26 embryo 04-06hr    12 embryo 06-08hr    11 embryo 08-10hr    14 embryo 10-12hr    19 embryo 12-14hr    17 embryo 14-16hr    20 embryo 16-18hr    30 embryo 18-20hr    19 embryo 20-22hr    9 embryo 22-24hr    11 larva L1    9 larva L2    10 larva L3 12hr old    11 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    50 white prepupae new    97 white prepupae 12hr    25 white prepupae 24hr    22 pupae 2d postWPP    31 pupae 3d postWPP    47 pupae 4d postWPP    18 adult male 01day    31 adult male 05day    34 adult male 30day    27 adult female 01day    24 adult female 05day    39 adult female 30day    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (58) embryo 02-04hr  26 embryo 04-06hr    12 embryo 06-08hr    11 embryo 08-10hr    14 embryo 10-12hr    19 embryo 12-14hr    17 embryo 14-16hr    20 embryo 16-18hr  30 embryo 18-20hr    19 embryo 20-22hr    9 embryo 22-24hr    11 larva L1    9 larva L2    10 larva L3 12hr old    11 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9  (50) white prepupae new  (97) white prepupae 12hr    25 white prepupae 24hr    22 pupae 2d postWPP  31 pupae 3d postWPP  (47) pupae 4d postWPP    18 adult male 01day  31 adult male 05day  (34) adult male 30day  27 adult female 01day    24 adult female 05day  (39) adult female 30day  (40) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    58 embryo 02-04hr    26 embryo 04-06hr    12 embryo 06-08hr    11 embryo 08-10hr    14 embryo 10-12hr    19 embryo 12-14hr    17 embryo 14-16hr    20 embryo 16-18hr    30 embryo 18-20hr    19 embryo 20-22hr    9 embryo 22-24hr    11 larva L1    9 larva L2    10 larva L3 12hr old    11 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    50 white prepupae new    97 white prepupae 12hr    25 white prepupae 24hr    22 pupae 2d postWPP    31 pupae 3d postWPP    47 pupae 4d postWPP    18 adult male 01day    31 adult male 05day    34 adult male 30day    27 adult female 01day    24 adult female 05day    39 adult female 30day    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    58 embryo 02-04hr    26 embryo 04-06hr    12 embryo 06-08hr    11 embryo 08-10hr    14 embryo 10-12hr    19 embryo 12-14hr    17 embryo 14-16hr    20 embryo 16-18hr    30 embryo 18-20hr    19 embryo 20-22hr    9 embryo 22-24hr    11 larva L1    9 larva L2    10 larva L3 12hr old    11 larva L3 puffstage 1-2    11 larva L3 puffstage 3-6    20 larva L3 puffstage 7-9    50 white prepupae new    97 white prepupae 12hr    25 white prepupae 24hr    22 pupae 2d postWPP    31 pupae 3d postWPP    47 pupae 4d postWPP    18 adult male 01day    31 adult male 05day    34 adult male 30day    27 adult female 01day    24 adult female 05day    39 adult female 30day    40 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    8 embryonic 1182-4H    9 embryonic GM2    6 embryonic Kc167    15 embryonic S1    12 embryonic S3    10 leg disc CME L1    10 wing disc CME-W2    7 wing disc ML-DmD8    9 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    13 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    13 antennal disc ML-DmD20-c5    11 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    19 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    10 ovary fGS/OSS    7 ovary OSC    10 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    8 embryonic 1182-4H    9 embryonic GM2    6 embryonic Kc167    15 embryonic S1    12 embryonic S3    10 leg disc CME L1    10 wing disc CME-W2    7 wing disc ML-DmD8    9 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    13 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    13 antennal disc ML-DmD20-c5    11 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    19 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    10 ovary fGS/OSS    7 ovary OSC    10 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    8 embryonic 1182-4H    9 embryonic GM2    6 embryonic Kc167    15 embryonic S1    12 embryonic S3    10 leg disc CME L1    10 wing disc CME-W2    7 wing disc ML-DmD8    9 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    13 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    13 antennal disc ML-DmD20-c5    11 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    19 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    10 ovary fGS/OSS    7 ovary OSC    10 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    8 embryonic 1182-4H    9 embryonic GM2    6 embryonic Kc167    15 embryonic S1    12 embryonic S3    10 leg disc CME L1    10 wing disc CME-W2    7 wing disc ML-DmD8    9 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    13 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    13 antennal disc ML-DmD20-c5    11 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    19 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    10 ovary fGS/OSS    7 ovary OSC    10 ovary OSS    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    8 embryonic 1182-4H    9 embryonic GM2    6 embryonic Kc167    15 embryonic S1    12 embryonic S3    10 leg disc CME L1    10 wing disc CME-W2    7 wing disc ML-DmD8    9 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    13 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    13 antennal disc ML-DmD20-c5    11 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    19 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    10 ovary fGS/OSS    7 ovary OSC    10 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    8 embryonic 1182-4H    9 embryonic GM2    6 embryonic Kc167    15 embryonic S1    12 embryonic S3    10 leg disc CME L1    10 wing disc CME-W2    7 wing disc ML-DmD8    9 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    13 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    13 antennal disc ML-DmD20-c5    11 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    19 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    10 ovary fGS/OSS    7 ovary OSC    10 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    8 embryonic 1182-4H    9 embryonic GM2    6 embryonic Kc167    15 embryonic S1    12 embryonic S3    10 leg disc CME L1    10 wing disc CME-W2    7 wing disc ML-DmD8    9 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    13 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    13 antennal disc ML-DmD20-c5    11 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    19 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    10 ovary fGS/OSS    7 ovary OSC    10 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    11 Schneider line 2 Sg4    8 embryonic 1182-4H    9 embryonic GM2    6 embryonic Kc167    15 embryonic S1    12 embryonic S3    10 leg disc CME L1    10 wing disc CME-W2    7 wing disc ML-DmD8    9 wing disc ML-DmD9    13 wing disc ML-DmD16-c3    24 wing disc ML-DmD21    13 wing disc ML-DmD32    14 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    13 antennal disc ML-DmD20-c5    11 mixed discs ML-DmD4-c1    15 CNS ML-DmBG1-c1    19 CNS ML-DmBG2-c2    10 tumorous blood cells mbn2    10 ovary fGS/OSS    7 ovary OSC    10 ovary OSS    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    15 heat shock, 4-day adult    23 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    22 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    47 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    35 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    25 Ethanol 2.5% 3 hrs, larvae L3    39 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    41 Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult    44 Paraquat 10 mM 48 hrs, 4-day adult    36 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    15 heat shock, 4-day adult    23 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    22 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult  (47) Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult  (35) Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    25 Ethanol 2.5% 3 hrs, larvae L3  (39) Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (41) Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult  (44) Paraquat 10 mM 48 hrs, 4-day adult  (36) Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    15 heat shock, 4-day adult    23 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    22 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    47 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    35 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    25 Ethanol 2.5% 3 hrs, larvae L3    39 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    41 Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult    44 Paraquat 10 mM 48 hrs, 4-day adult    36 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    15 heat shock, 4-day adult    23 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    22 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    47 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    35 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    25 Ethanol 2.5% 3 hrs, larvae L3    39 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    41 Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult    44 Paraquat 10 mM 48 hrs, 4-day adult    36 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    15 heat shock, 4-day adult    23 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    22 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    47 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    35 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    25 Ethanol 2.5% 3 hrs, larvae L3    39 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    41 Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult    44 Paraquat 10 mM 48 hrs, 4-day adult    36 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    15 heat shock, 4-day adult    23 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    22 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult  (47) Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult  (35) Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    25 Ethanol 2.5% 3 hrs, larvae L3  (39) Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (41) Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult  (44) Paraquat 10 mM 48 hrs, 4-day adult  (36) Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    15 heat shock, 4-day adult    23 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    22 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    47 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    35 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    25 Ethanol 2.5% 3 hrs, larvae L3    39 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    41 Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult    44 Paraquat 10 mM 48 hrs, 4-day adult    36 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    18 cold shock, 4-day adult    15 heat shock, 4-day adult    23 Cadmium 50 mM 6 hrs, larvae L3    9 Cadmium 50 mM 12 hrs, larvae L3    22 Cadmium 50 mM 48 hrs, 4-day adult    25 Cadmium 100 mM 48 hrs, 4-day adult    47 Copper 0.5 mM 12 hrs, larvae L3    10 Copper 15 mM 48 hrs, 4-day adult    35 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    25 Ethanol 2.5% 3 hrs, larvae L3    39 Ethanol 5% 3 hrs, larvae L3    9 Ethanol 10% 3 hrs, larvae L3    10 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    41 Caffeine 25 mg/ml 48 hrs, 4-day adult    22 Paraquat 5 mM 48 hrs, 4-day adult    44 Paraquat 10 mM 48 hrs, 4-day adult    36 Rotenone 2 μg 12 hrs, larvae L3    10 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_27
External Data & Images
Linkouts	BDGP expression data • LD21794 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0027515 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7115-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG7115 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG7115GD982 Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of CG7115 Class Mutagen Stocks Known lesion CG7115c05817 piggyBac transposase 1 -- CG7115CB-5833-3 1 -- CG7115KG02655 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG7115 Class Mutagen Stocks Known lesion CG7115GD982 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG7115HMS01985 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG7115KK100168 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel7032 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD982} NA P{KK100168} NA P{TRiP.HMS01985} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{RS3}CG7115CB-5833-3 NA P{SUPor-P}CG7115KG02655 NA PBac{PB}CG7115c05817 NA
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
cell adhesion inferred from mutant phenotype (Kiger et al., 2003) regulation of cell shape inferred from mutant phenotype (Kiger et al., 2003)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
protein serine/threonine phosphatase activity inferred from sequence or structural similarity with EMBL:AF117832 (FlyBase, 1992-) non-traceable author statement (Morrison et al., 2000)
Biological Process
CV term Evidence References
protein dephosphorylation inferred from electronic annotation with InterPro:IPR000222 (FlyBase Curators et al., 2004-) non-traceable author statement (Morrison et al., 2000)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	gene_with_edited_transcript (Graveley et al., 2011) nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG7115 - Atx2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7115 - CG12264 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7115 - CG1785 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7115 - CG3817 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7115 - CG3887 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7115 - CG6701 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7115 - CG7878 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7115 - Cbp80 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7115 - Eb1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7115 - Elongin-B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7115 - NHP2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7115 - SmG anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7115 - Syp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7115 - Zn72D anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7115 - mRpL15 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7115 - mRpL4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7115 - mTerf3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG7115 - qkr54B anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG7115 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 60208 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0027515 DroID - A comprehensive database of gene and protein interactions. • FBgn0027515 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34069
Orthologs
OrthoDB Orthologs (37) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG62RDT1 Dipteran inclusive ortholog search EOG6CJVRF Insect inclusive ortholog search EOG6D51SX Arthropod inclusive ortholog search EOG6MCVFM Metazoa inclusive ortholog search EOG664C5Q
Orthologs in Drosophila Species (EOG62RDT1)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG7115     Drosophila simulans   Dsim\GD23491 Y   Drosophila sechellia   Dsec\GM16598 Y   Drosophila erecta   Dere\GG10499 Y   Drosophila yakuba   Dyak\GE14637 Y   Drosophila ananassae   Dana\GF21820 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA20114 Y   Drosophila persimilis   Dper\GL18645 Y   Drosophila willistoni   Dwil\GK14821 Y   Drosophila virilis   Dvir\GJ11141 Y   Drosophila mojavensis   Dmoj\GI21350 Y   Drosophila grimshawi   Dgri\GH10360 Y
Orthologs in non-Drosophila Dipterans (EOG6CJVRF)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL004709   Anopheles gambiae Malaria mosquito  Agam\AGAP008536   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ008870
Orthologs in non-Dipteran Insects (EOG6D51SX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC552068   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG011160   Camponotus floridanus Florida carpenter ant  Cflo\CFLO19639   Linepithema humile Argentine ant  Lhum\LH13245   Pogonomyrmex barbatus Red harvester ant  Pbar\PB26237   Pogonomyrmex barbatus Red harvester ant  Pbar\PB18295   Solenopsis invicta Red fire ant  Sinv\SINV17933   Solenopsis invicta Red fire ant  Sinv\SINV13969   Solenopsis invicta Red fire ant  Sinv\SINV13971   Acyrthosiphon pisum Pea aphid  Apim\ACYPI001182   Bombyx mori Silkmoth  Bmor\BGIBMGA005975   Pediculus humanus Human body louse  Phum\PHUM151050   Tribolium castaneum Red flour beetle  Tcas\TC014396
Orthologs in non-Insect Arthropods (EOG6MCVFM)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Ixodes scapularis Deer tick  Isca\ISCW004621
Orthologs in non-Arthropod Metazoa (EOG664C5Q)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_006132gn   Danio rerio Zebrafish  Drer\DKEY-119F1.3   Danio rerio Zebrafish  Drer\ppm1lb   Xenopus tropicalis Western clawed frog  Xtro\ppm1l   Gallus gallus Domestic chicken  Ggal\PPM1L   Mus musculus House mouse  Mmus\Ppm1l   Rattus norvegicus Norway rat  Rnor\Ppm1l   Homo sapiens Human  Hsap\ENSG00000163590
Human Orthologs (1)
Gene OMIM HGNC Hsap\ENSG00000163590
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD23491 Drosophila sechellia Dsec\GM16598 Drosophila erecta Dere\GG10499 Drosophila yakuba Dyak\GE14637 Drosophila ananassae Dana\GF21820 Drosophila pseudoobscura pseudoobscura Dpse\GA20114 Drosophila persimilis Dper\GL18645 Drosophila willistoni Dwil\GK14821 Drosophila virilis Dvir\GJ11141 Drosophila mojavensis Dmoj\GI21350 Drosophila grimshawi Dgri\GH10360
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	14190 y1 w67c23; P{SUPor-P}CG7115KG02655 39065 y1 v1; P{TRiP.HMS01985}attP2/TM3, Sb1
Harvard	- PBac{PB}CG7115c05817
Kyoto	123842 w1118; P{RS3}CG7115CB-5833-3
VDRC	v103354 P{KK100168}VIE-260B v9404 w1118; P{GD982}v9404/TM3
Genomic Clones ( 3 )
	BACR09A04 BACR16J09 BACR31D05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 149 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD21794
Other clones	DPiM_LD21794 MIP22288
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT08783 AT13304 AT20569 GH04248 GH05287 GH26831 HL02022 LD11137 LD30327 LD47316 RE04247 RE08295 RE10544 RE10923 RE35507 RE43042 RE62010 RE66744
Other clones	516 519 1116 12418 34589 35564 38476 39988 59361 74175 78055 106802 bs15f09 CK01.107B.E5 Dmel_dig_017472_0676_1027 Dmel_neb_013618_0089_1830 EC051104 EC051124 EC052628 EC054108 EC055687 EC056165 EK089519 EK100508 EK113510 EK121563 EK122018 EK151311 EK153458 EK163606 EK183833 EK190008 EK204047 EK244354 RE01779 RP003007254 RP003027216 RP003030353 RP003031610 RP003045966 RP003075164 RP003091838 RP003093887 RP003113015 RP003116888 RP003133381 RP003143661 RP003144032 RP003147213 RP003158456 RP003168796 RP003175634 RP003181708 RP003182959 RP003183038 RP003184388 RP003205263 RP003213191 RP003217652 RP003229833 RP003235265 RP003236392 RP003237288 RP003243765 RP003250574 RP003252546 RP003276058 RP003281328 RP003283361 RP003285797 RP003311573 RP003313393 RP003315784 RP003316968 RP003326393 RP003336306 RP003342392 RP003344583 RP003344821 RP003358985 RP003414505 RP003419065 RP003421478 RP003426412 RP003435529 RP003436349 RP003443090 RP003449450 RP003461979 RP003464352 RP003465972 RP003470308 RP003474736 RP003479423 RP003491562 RP003500903 RP003502732 RP003512951 RP003530422 RP003536205 RP003537578 RP003545380 RP003547955 RP003551951 RP003553420 RP003553502 RP003555022 RP003556924 RP003568751 RP003570933 RP003589343 RP003599919 RP003606119 RP003612984 RP003613955 RP003618758 RP003627789 RP003638742 RP003640536 RP003646385 RP003646395 RP003650449 RP003651558 RP003653312 RP003654953 RP003659681 RP003667447 RP003672612
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0027515 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34069
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a phenotype when assayed in S2R+ cells: cells become round and detached. Kc167 cells are unaffected. (Kiger et al., 2003) dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_135310 NM_164774 NM_001273285 NM_001273286 NM_001273287 RefSeq (Proteins) • NP_609154 NP_723320 NP_001260214 NP_001260215 NP_001260216 DDBJ / EMBL / GenBank • AA816936 AAD34773 AAF52564 AAF52565 AF132185 AGB92750 AGB92751 AGB92752 AI064006 AI455214 AI945687 BH840514 CZ470276 Entrez Gene - A searchable database of RefSeq genes. • 34069 UniProtKB/TrEMBL • Q9XZ28
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Protein phosphatase 2C, manganese/magnesium aspartate binding site (IPR000222) Protein phosphatase 2C (PP2C)-like (IPR001932) Protein phosphatase 2C (IPR015655) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LD21794
Linkouts
	BioGRID - A database of protein and genetic interactions • 60208 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0027515 DroID - A comprehensive database of gene and protein interactions. • FBgn0027515 DRSC - Results from RNAi screens. • FBgn0027515 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0027515 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7115-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0027515 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34069 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34069 modMine - Data generated by the modENCODE project. • FBgn0027515
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	BcDNA:LD21794 (Bronstein et al., 2010) CG7115 (Dorus et al., 2006, Keleman et al., 2009.8.5, Bronstein et al., 2010, Mackay et al., 2012, Ni et al., 2010.12.1, Gurudatta et al., 2012) PP2C (Morrison et al., 2000)
Name Synonym
Secondary FlyBase IDs
References ( 30 )
Generate a list of	All references relating to this gene ( 30 )
List References by type	Research paper  ( 7 ) Supplementary material  ( 7 ) Personal communication to FlyBase  ( 10 ) FlyBase analysis  ( 2 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 4 )
	Gurudatta et al., 2012, Dev. Biol. 369(1): 124--132 The BEAF insulator regulates genes involved in cell polarity and neoplastic growth. [FBrf0219796] Mackay et al., 2012, Nature 482(7384): 173--178 The Drosophila melanogaster Genetic Reference Panel. [FBrf0217434] Spasic et al., 2012, PLoS Genet. 8(1): e1002433 Genome-Wide Assessment of AU-Rich Elements by the AREScore Algorithm. [FBrf0217189] Horn et al., 2011, Nat. Methods 8(4): 341--346 Mapping of signaling networks through synthetic genetic interaction analysis by RNAi. [FBrf0213352] Show all research papers ...