BcDNA:GH11110 , DmSSp, dOTT
mRNA-binding factor - m(6)A methyltransferase complex component - sex determination - fat body - counteracts Split ends function in fat regulation - stimulates axon outgrowth during neurosecretory cell remodeling - promotes Wingless signaling
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.49
Component of the WMM complex, a N6-methyltransferase complex composed of a catalytic subcomplex, named MAC, and of an associated subcomplex, named MACOM (PubMed:27919077, PubMed:29535189, PubMed:28675155, PubMed:29555755). The MAC subcomplex is composed of Ime4/Mettl3 and Mettl14 (PubMed:27919077, PubMed:29535189, PubMed:28675155, PubMed:29555755). The MACOM subcomplex is composed of fl(2)d, Flacc/Xio, Hakai, vir, and, in some cases of nito (PubMed:27919077, PubMed:29535189, PubMed:29555755). Interacts with Sxl (PubMed:26324914). Interacts with Hipk; leading to phosphorylation (PubMed:25040100).
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\nito using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\nito in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for identity of: nito BcDNA:GH11110