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Gene Dmel\CG10345

General Information
Symbol	Dmel\CG10345	Species	D. melanogaster
Name		Annotation symbol	CG10345
Feature type	protein_coding_gene	FlyBase ID	FBgn0027562
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	89D5-89D5	Sequence location	3R:12,422,795..12,430,510 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG10345 (FBgn0027562). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: scavenger receptor activity. It is reported to be involved in the biological process: defense response. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Adhesion molecule CD36; CD36 antigen. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult head, adult crop. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, adult hindgut, larval trachea, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1637198_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG10345. Gene sequence location is 3R:12422795..12430510.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features HFA14138 BKN27266 References Herboso et al., 2011, Int. J. Dev. Biol. 55(6): 603--611
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 89D5-89D5   Limits computationally determined from genome sequence between P{lacW}CSN5L4032 and P{EP}MESK4EP1015
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG10345 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG10345-RA FBtr0083360  NM_142306   2350   552
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG10345-PA   FBpp0082805   62.6   552   7.11     NP_650563   AAF55338
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • CD36 antigen (IPR002159) Adhesion molecule CD36 (IPR005428)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA567958   AE014297 AAF55338   AF145651 AAD38626   AI109548   AI402145   BE662151   BF494444   BF501294   BG634719   BT044340   CA804929   CO183465   CO284831   CO292270   CO292542   CO302387   CO316671   CZ467339   CZ467340   CZ469058   CZ469859   EC057113   EC200111   EC201146   EC212422   EC226917
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VET1 Q9Y121
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0027562    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0027562 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of extremely low expression. Peak expression observed during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0027562 expression level Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    11 embryo 04-06hr    4 embryo 06-08hr    6 embryo 08-10hr    21 embryo 10-12hr    15 embryo 12-14hr    21 embryo 14-16hr    166 embryo 16-18hr    1163 embryo 18-20hr    2848 embryo 20-22hr    471 embryo 22-24hr    639 larva L1    192 larva L2    236 larva L3 12hr old    242 larva L3 puffstage 1-2    125 larva L3 puffstage 3-6    68 larva L3 puffstage 7-9    56 white prepupae new    41 white prepupae 12hr    13432 white prepupae 24hr    614 pupae 2d postWPP    1090 pupae 3d postWPP    397 pupae 4d postWPP    5427 adult male 01day    2014 adult male 05day    2101 adult male 30day    2204 adult female 01day    1014 adult female 05day    541 adult female 30day    399 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    11 embryo 04-06hr    4 embryo 06-08hr    6 embryo 08-10hr    21 embryo 10-12hr    15 embryo 12-14hr    21 embryo 14-16hr  (166) embryo 16-18hr  (1163) embryo 18-20hr  (2848) embryo 20-22hr  (471) embryo 22-24hr  (639) larva L1  (192) larva L2  (236) larva L3 12hr old  (242) larva L3 puffstage 1-2  (125) larva L3 puffstage 3-6    68 larva L3 puffstage 7-9    56 white prepupae new    41 white prepupae 12hr  (13432) white prepupae 24hr  (614) pupae 2d postWPP  (1090) pupae 3d postWPP  (397) pupae 4d postWPP  (5427) adult male 01day  (2014) adult male 05day  (2101) adult male 30day  (2204) adult female 01day  (1014) adult female 05day  (541) adult female 30day  (399) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    11 embryo 04-06hr    4 embryo 06-08hr    6 embryo 08-10hr    21 embryo 10-12hr    15 embryo 12-14hr    21 embryo 14-16hr    166 embryo 16-18hr    1163 embryo 18-20hr  (2848) embryo 20-22hr    471 embryo 22-24hr    639 larva L1    192 larva L2    236 larva L3 12hr old    242 larva L3 puffstage 1-2    125 larva L3 puffstage 3-6    68 larva L3 puffstage 7-9    56 white prepupae new    41 white prepupae 12hr  (13432) white prepupae 24hr    614 pupae 2d postWPP    1090 pupae 3d postWPP    397 pupae 4d postWPP  (5427) adult male 01day  (2014) adult male 05day  (2101) adult male 30day  (2204) adult female 01day    1014 adult female 05day    541 adult female 30day    399 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    11 embryo 04-06hr    4 embryo 06-08hr    6 embryo 08-10hr    21 embryo 10-12hr    15 embryo 12-14hr    21 embryo 14-16hr    166 embryo 16-18hr    1163 embryo 18-20hr    2848 embryo 20-22hr    471 embryo 22-24hr    639 larva L1    192 larva L2    236 larva L3 12hr old    242 larva L3 puffstage 1-2    125 larva L3 puffstage 3-6    68 larva L3 puffstage 7-9    56 white prepupae new    41 white prepupae 12hr  (13432) white prepupae 24hr    614 pupae 2d postWPP    1090 pupae 3d postWPP    397 pupae 4d postWPP    5427 adult male 01day    2014 adult male 05day    2101 adult male 30day    2204 adult female 01day    1014 adult female 05day    541 adult female 30day    399 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    11 embryo 04-06hr    4 embryo 06-08hr    6 embryo 08-10hr    21 embryo 10-12hr    15 embryo 12-14hr    21 embryo 14-16hr    166 embryo 16-18hr    1163 embryo 18-20hr    2848 embryo 20-22hr    471 embryo 22-24hr    639 larva L1    192 larva L2    236 larva L3 12hr old    242 larva L3 puffstage 1-2    125 larva L3 puffstage 3-6    68 larva L3 puffstage 7-9    56 white prepupae new    41 white prepupae 12hr    13432 white prepupae 24hr    614 pupae 2d postWPP    1090 pupae 3d postWPP    397 pupae 4d postWPP    5427 adult male 01day    2014 adult male 05day    2101 adult male 30day    2204 adult female 01day    1014 adult female 05day    541 adult female 30day    399 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0027562 expression level Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    11 embryo 04-06hr    4 embryo 06-08hr    6 embryo 08-10hr    21 embryo 10-12hr    15 embryo 12-14hr    21 embryo 14-16hr    166 embryo 16-18hr    1163 embryo 18-20hr    2848 embryo 20-22hr    471 embryo 22-24hr    639 larva L1    192 larva L2    236 larva L3 12hr old    242 larva L3 puffstage 1-2    125 larva L3 puffstage 3-6    68 larva L3 puffstage 7-9    56 white prepupae new    41 white prepupae 12hr    13432 white prepupae 24hr    614 pupae 2d postWPP    1090 pupae 3d postWPP    397 pupae 4d postWPP    5427 adult male 01day    2014 adult male 05day    2101 adult male 30day    2204 adult female 01day    1014 adult female 05day    541 adult female 30day    399 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    11 embryo 04-06hr    4 embryo 06-08hr    6 embryo 08-10hr    21 embryo 10-12hr    15 embryo 12-14hr    21 embryo 14-16hr  (166) embryo 16-18hr  (1163) embryo 18-20hr  (2848) embryo 20-22hr  (471) embryo 22-24hr  (639) larva L1  (192) larva L2  (236) larva L3 12hr old  (242) larva L3 puffstage 1-2  125 larva L3 puffstage 3-6    68 larva L3 puffstage 7-9    56 white prepupae new    41 white prepupae 12hr  (13432) white prepupae 24hr  (614) pupae 2d postWPP  (1090) pupae 3d postWPP  (397) pupae 4d postWPP  (5427) adult male 01day  (2014) adult male 05day  (2101) adult male 30day  (2204) adult female 01day  (1014) adult female 05day  (541) adult female 30day  (399) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    11 embryo 04-06hr    4 embryo 06-08hr    6 embryo 08-10hr    21 embryo 10-12hr    15 embryo 12-14hr    21 embryo 14-16hr    166 embryo 16-18hr    1163 embryo 18-20hr  (2848) embryo 20-22hr    471 embryo 22-24hr    639 larva L1    192 larva L2    236 larva L3 12hr old    242 larva L3 puffstage 1-2    125 larva L3 puffstage 3-6    68 larva L3 puffstage 7-9    56 white prepupae new    41 white prepupae 12hr  (13432) white prepupae 24hr    614 pupae 2d postWPP    1090 pupae 3d postWPP    397 pupae 4d postWPP  (5427) adult male 01day  2014 adult male 05day  2101 adult male 30day  2204 adult female 01day    1014 adult female 05day    541 adult female 30day    399 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    11 embryo 04-06hr    4 embryo 06-08hr    6 embryo 08-10hr    21 embryo 10-12hr    15 embryo 12-14hr    21 embryo 14-16hr    166 embryo 16-18hr    1163 embryo 18-20hr    2848 embryo 20-22hr    471 embryo 22-24hr    639 larva L1    192 larva L2    236 larva L3 12hr old    242 larva L3 puffstage 1-2    125 larva L3 puffstage 3-6    68 larva L3 puffstage 7-9    56 white prepupae new    41 white prepupae 12hr  13432 white prepupae 24hr    614 pupae 2d postWPP    1090 pupae 3d postWPP    397 pupae 4d postWPP    5427 adult male 01day    2014 adult male 05day    2101 adult male 30day    2204 adult female 01day    1014 adult female 05day    541 adult female 30day    399 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    11 embryo 04-06hr    4 embryo 06-08hr    6 embryo 08-10hr    21 embryo 10-12hr    15 embryo 12-14hr    21 embryo 14-16hr    166 embryo 16-18hr    1163 embryo 18-20hr    2848 embryo 20-22hr    471 embryo 22-24hr    639 larva L1    192 larva L2    236 larva L3 12hr old    242 larva L3 puffstage 1-2    125 larva L3 puffstage 3-6    68 larva L3 puffstage 7-9    56 white prepupae new    41 white prepupae 12hr    13432 white prepupae 24hr    614 pupae 2d postWPP    1090 pupae 3d postWPP    397 pupae 4d postWPP    5427 adult male 01day    2014 adult male 05day    2101 adult male 30day    2204 adult female 01day    1014 adult female 05day    541 adult female 30day    399 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0027562    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0027562 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult head, adult crop. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, adult hindgut, larval trachea, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0027562 expression level Tissue   Expression Level Larval Central Nervous System    3.475 Larval Midgut    5.6 Larval Hindgut    52.6 Larval Malpighian Tubules    4.8 Larval Fat Body    8 Larval Salivary Gland    44.1 Larval Trachea    158.325 Larval Carcass    5.425 Adult Head    576.6 Adult Eye    270.4 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion    5.3 Adult Crop    709 Adult Midgut no informative data Adult Hindgut    253.6 Adult Malpighian Tubules    9.8 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    19.925 Adult VirginFemale Spermatheca    4.9 Adult InseminatedFemale Spermatheca    4.5 Adult Ovary    0.9 Adult Testis    46.7 Adult Male Accessory Gland    3.7 Adult Carcass    468 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    3.475 Larval Midgut    5.6 Larval Hindgut    52.6 Larval Malpighian Tubules    4.8 Larval Fat Body    8 Larval Salivary Gland    44.1 Larval Trachea    158.325 Larval Carcass    5.425 Adult Head  (576.6) Adult Eye    270.4 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion    5.3 Adult Crop  (709) Adult Midgut no informative data Adult Hindgut    253.6 Adult Malpighian Tubules    9.8 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    19.925 Adult VirginFemale Spermatheca    4.9 Adult InseminatedFemale Spermatheca    4.5 Adult Ovary    0.9 Adult Testis    46.7 Adult Male Accessory Gland    3.7 Adult Carcass    468 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    3.475 Larval Midgut    5.6 Larval Hindgut    52.6 Larval Malpighian Tubules    4.8 Larval Fat Body    8 Larval Salivary Gland    44.1 Larval Trachea    158.325 Larval Carcass    5.425 Adult Head    576.6 Adult Eye    270.4 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion    5.3 Adult Crop    709 Adult Midgut no informative data Adult Hindgut    253.6 Adult Malpighian Tubules    9.8 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    19.925 Adult VirginFemale Spermatheca    4.9 Adult InseminatedFemale Spermatheca    4.5 Adult Ovary    0.9 Adult Testis    46.7 Adult Male Accessory Gland    3.7 Adult Carcass    468 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    3.475 Larval Midgut    5.6 Larval Hindgut    52.6 Larval Malpighian Tubules    4.8 Larval Fat Body    8 Larval Salivary Gland    44.1 Larval Trachea    158.325 Larval Carcass    5.425 Adult Head    576.6 Adult Eye    270.4 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion    5.3 Adult Crop    709 Adult Midgut no informative data Adult Hindgut    253.6 Adult Malpighian Tubules    9.8 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    19.925 Adult VirginFemale Spermatheca    4.9 Adult InseminatedFemale Spermatheca    4.5 Adult Ovary    0.9 Adult Testis    46.7 Adult Male Accessory Gland    3.7 Adult Carcass    468 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0027562 expression level Tissue   Expression Level Larval Central Nervous System    3.475 Larval Midgut    5.6 Larval Hindgut    52.6 Larval Malpighian Tubules    4.8 Larval Fat Body    8 Larval Salivary Gland    44.1 Larval Trachea    158.325 Larval Carcass    5.425 Adult Head    576.6 Adult Eye    270.4 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion    5.3 Adult Crop    709 Adult Midgut no informative data Adult Hindgut    253.6 Adult Malpighian Tubules    9.8 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    19.925 Adult VirginFemale Spermatheca    4.9 Adult InseminatedFemale Spermatheca    4.5 Adult Ovary    0.9 Adult Testis    46.7 Adult Male Accessory Gland    3.7 Adult Carcass    468 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    3.475 Larval Midgut    5.6 Larval Hindgut    52.6 Larval Malpighian Tubules    4.8 Larval Fat Body    8 Larval Salivary Gland    44.1 Larval Trachea    158.325 Larval Carcass    5.425 Adult Head  576.6 Adult Eye    270.4 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion    5.3 Adult Crop  709 Adult Midgut no informative data Adult Hindgut    253.6 Adult Malpighian Tubules    9.8 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    19.925 Adult VirginFemale Spermatheca    4.9 Adult InseminatedFemale Spermatheca    4.5 Adult Ovary    0.9 Adult Testis    46.7 Adult Male Accessory Gland    3.7 Adult Carcass    468 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    3.475 Larval Midgut    5.6 Larval Hindgut    52.6 Larval Malpighian Tubules    4.8 Larval Fat Body    8 Larval Salivary Gland    44.1 Larval Trachea    158.325 Larval Carcass    5.425 Adult Head    576.6 Adult Eye    270.4 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion    5.3 Adult Crop    709 Adult Midgut no informative data Adult Hindgut    253.6 Adult Malpighian Tubules    9.8 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    19.925 Adult VirginFemale Spermatheca    4.9 Adult InseminatedFemale Spermatheca    4.5 Adult Ovary    0.9 Adult Testis    46.7 Adult Male Accessory Gland    3.7 Adult Carcass    468 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    3.475 Larval Midgut    5.6 Larval Hindgut    52.6 Larval Malpighian Tubules    4.8 Larval Fat Body    8 Larval Salivary Gland    44.1 Larval Trachea    158.325 Larval Carcass    5.425 Adult Head    576.6 Adult Eye    270.4 Adult Brain no informative data Adult Thoracic-Abdominal Ganglion    5.3 Adult Crop    709 Adult Midgut no informative data Adult Hindgut    253.6 Adult Malpighian Tubules    9.8 Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart    19.925 Adult VirginFemale Spermatheca    4.9 Adult InseminatedFemale Spermatheca    4.5 Adult Ovary    0.9 Adult Testis    46.7 Adult Male Accessory Gland    3.7 Adult Carcass    468 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain no informative data Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut no informative data Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body no informative data Adult Salivary Gland no informative data Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    576.6   NA  Eye    270.4   NA  Brain    no informative data   3.475  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    5.3   NA  Crop    709   5.6  Midgut    no informative data   52.6  Hindgut    253.6   4.8  Malpighian Tubules    9.8   8  Fat Body    no informative data   44.1  Salivary Gland    no informative data   NA  Heart    19.925   158.325  Trachea    NA   NA  VirginFemale Spermatheca    4.9   NA  InseminatedFemale Spermatheca    4.5   NA  Ovary    0.9   NA  Testis    46.7   NA  Male Accessory Gland    3.7   5.425  Carcass    468 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_24
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0027562 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10345-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG10345c01661 Sterility Allele fertile CG10345c01661 Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of CG10345 Class Mutagen Stocks Known lesion CG10345c01661 piggyBac transposase 2 -- CG10345c05301 piggyBac transposase 1 -- CG10345c04191 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG10345 Class Mutagen Stocks Known lesion CG10345GD3023 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG10345KK107266 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6270 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD3023} NA P{KK107266} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{PB}CG10345c01661 NA PBac{PB}CG10345c04191 NA PBac{PB}CG10345c05301 NA
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
scavenger receptor activity non-traceable author statement (Lemaitre, 2000.12.20)
Biological Process
CV term Evidence References
cell adhesion inferred from electronic annotation with InterPro:IPR002159, InterPro:IPR005428 (FlyBase Curators et al., 2004-) defense response non-traceable author statement (Lemaitre, 2000.12.20)
Cellular Component
CV term Evidence References
integral to plasma membrane non-traceable author statement (Lemaitre, 2000.12.20) membrane inferred from electronic annotation with InterPro:IPR002159 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG10345 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0027562 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42017
Orthologs
Genome-wide drosophilid orthologs	Dana\GF17933 Dere\GG16822 Dgri\GH20494 Dmoj\GI10385 Dper\GL27292 Dpse\GA10261 Dsec\GM15420 Dsim\GD20277 Dvir\GJ22846 Dwil\GK22834 Dyak\GE26139
Curated drosophilid orthologs	Dpse\GA10261
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL002741-PA Aedes aegypti (mosquito) AGAP004643-PA Anopheles gambiae (mosquito) XP_396085.3 Apis mellifera (honey bee) XP_001947533.1 Acyrthosiphon pisum (pea aphid) BGIBMGA013572-PA Bombyx mori (silk worm) CPIJ017565 Culex pipens (mosquito) XP_001600667.1 Nasonia vitripennis (wasp) PHUM000861-PA Pediculus humanus (human body louse) XP_969679.2 Tribolium castaneum (red flour beetle) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV12100 LH17364 FBgn0243177 FBgn0224796 FBgn0209950 FBgn0191752 FBgn0170338 FBgn0070319 FBgn0164873 FBgn0133149 FBgn0127957 FBgn0124985 FBgn0109052 FBgn0094951 CPIJ017565 BGIBMGA013572 ACYPI010057 GB13813 SCRB6 PB21680 PHUM569120 GLEAN_00948
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	10668 w1118; PBac{PB}CG10345c01661
Harvard	- PBac{PB}CG10345c01661 - PBac{PB}CG10345c05301
VDRC	v100252 P{KK107266}VIE-260B v51536 w1118; P{GD3023}v51536 v51537 w1118; P{GD3023}v51537
Genomic Clones ( 1 )
	BACR48L13 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 19 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH08773
Other clones	FI07620
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT03045 AT16578 AT31029 HL02046
Other clones	55996 71497 72058 162206 bs25a07 CK01.8B.D12 EC25765 EK166934 EK184042 EK199638 EK200418 EK265620 ESG0115d.B21_C11
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0027562 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42017
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_142306 RefSeq (Proteins) • NP_650563 DDBJ / EMBL / GenBank • AAD38626 AAF55338 AF145651 AI109548 AI402145 BE662151 CZ467339 CZ467340 CZ469058 CZ469859 Entrez Gene - A searchable database of RefSeq genes. • 42017 UniProtKB/TrEMBL • Q9VET1 Q9Y121
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • CD36 antigen (IPR002159) Adhesion molecule CD36 (IPR005428)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0027562 DRSC - Results from RNAi screens. • FBgn0027562 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0027562 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10345-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0027562 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42017 InParanoid A subset of ortholog calls from InParanoid. • AAEL002741-PA Aedes aegypti (mosquito) AGAP004643-PA Anopheles gambiae (mosquito) XP_396085.3 Apis mellifera (honey bee) XP_001947533.1 Acyrthosiphon pisum (pea aphid) BGIBMGA013572-PA Bombyx mori (silk worm) CPIJ017565 Culex pipens (mosquito) XP_001600667.1 Nasonia vitripennis (wasp) PHUM000861-PA Pediculus humanus (human body louse) XP_969679.2 Tribolium castaneum (red flour beetle) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42017 modMine - Data generated by the modENCODE project. • FBgn0027562 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV12100 LH17364 FBgn0243177 FBgn0224796 FBgn0209950 FBgn0191752 FBgn0170338 FBgn0070319 FBgn0164873 FBgn0133149 FBgn0127957 FBgn0124985 FBgn0109052 FBgn0094951 CPIJ017565 BGIBMGA013572 ACYPI010057 GB13813 SCRB6 PB21680 PHUM569120 GLEAN_00948
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	BcDNA (Lemaitre, 2000.12.20) BcDNA:GH08773   CG10345 (Gilfillan et al., 2006, Ye et al., 2009, Nichols and Vogt, 2008, Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 17 )
Research paper	Herboso et al., 2011, Int. J. Dev. Biol. 55(6): 603--611 Expression of the Scavenger Receptor Class B type I (SR-BI) family in Drosophila melanogaster. [FBrf0216272] Ye et al., 2009, PLoS Pathog. 5(4): e1000385 Effective but costly, evolved mechanisms of defense against a virulent opportunistic pathogen in Drosophila melanogaster. [FBrf0207779] Nichols and Vogt, 2008, Insect Biochem. Mol. Biol. 38(4): 398--415 The SNMP/CD36 gene family in Diptera, Hymenoptera and Coleoptera: Drosophila melanogaster, D. pseudoobscura, Anopheles gambiae, Aedes aegypti, Apis mellifera, and Tribolium castaneum. [FBrf0204176] Gilfillan et al., 2006, Genes Dev. 20(7): 858--870 Chromosome-wide gene-specific targeting of the Drosophila dosage compensation complex. [FBrf0190543]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] Oliver, 2001.8.16, File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). File from B. Oliver containing information on ESTs expressed in the Drosophila testis, described in Andrews et al., 2000, Genome Res. 10(12): 2030-2043 (FBrf0132348). [FBrf0137492] Lemaitre, 2000.12.20, Drosophila immunity genes. Drosophila immunity genes. [FBrf0133282]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]