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Gene Dmel\CG3149

General Information
Symbol	Dmel\CG3149	Species	D. melanogaster
Name		Annotation symbol	CG3149
Feature type	protein_coding_gene	FlyBase ID	FBgn0027564
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	5A13-5A14	Sequence location	X:5,586,978..5,589,239 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG3149 (FBgn0027564). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: lipid transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: lipid transport. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: RFT1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, adult spermathecae, adult male accessory gland, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1639993_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG3149. Gene sequence location is X:5586978..5589239.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN20252 HFA17732
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 5A13-5A14   Limits computationally determined from genome sequence between P{EP}cvEP1349&P{EP}CG32758EP1368 and P{EP}EP404&P{EP}EP1405
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG3149 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG3149-RA FBtr0070846  NM_132018   2021   556
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG3149-PA   FBpp0070811   62.4   556   8.82     NP_572246   AAF46064
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • RFT1 (IPR007594)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA246966   AA264528   AE014298 AAF46064   AF145649 AAD38624   AI109255   AI402132   AI518819   AI533886   AI543417   AI546567   BI233240   BI237522   BI238240   BP545025   BP545026   CO328856   EC053354   EC056254   EC057993
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9Y123
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0027564    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0027564 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-12 hour embryonic stages, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0027564 expression level Developmental Stage   Expression Level embryo 00-02hr    1739 embryo 02-04hr    1342 embryo 04-06hr    2228 embryo 06-08hr    2033 embryo 08-10hr    1644 embryo 10-12hr    1857 embryo 12-14hr    934 embryo 14-16hr    1109 embryo 16-18hr    917 embryo 18-20hr    916 embryo 20-22hr    892 embryo 22-24hr    857 larva L1    1252 larva L2    1164 larva L3 12hr old    894 larva L3 puffstage 1-2    934 larva L3 puffstage 3-6    893 larva L3 puffstage 7-9    895 white prepupae new    836 white prepupae 12hr    799 white prepupae 24hr    828 pupae 2d postWPP    838 pupae 3d postWPP    1084 pupae 4d postWPP    1105 adult male 01day    1458 adult male 05day    1647 adult male 30day    1655 adult female 01day    1300 adult female 05day    1074 adult female 30day    1281 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1739) embryo 02-04hr  (1342) embryo 04-06hr  (2228) embryo 06-08hr  (2033) embryo 08-10hr  (1644) embryo 10-12hr  (1857) embryo 12-14hr  (934) embryo 14-16hr  (1109) embryo 16-18hr  (917) embryo 18-20hr  (916) embryo 20-22hr  (892) embryo 22-24hr  (857) larva L1  (1252) larva L2  (1164) larva L3 12hr old  (894) larva L3 puffstage 1-2  (934) larva L3 puffstage 3-6  (893) larva L3 puffstage 7-9  (895) white prepupae new  (836) white prepupae 12hr  (799) white prepupae 24hr  (828) pupae 2d postWPP  (838) pupae 3d postWPP  (1084) pupae 4d postWPP  (1105) adult male 01day  (1458) adult male 05day  (1647) adult male 30day  (1655) adult female 01day  (1300) adult female 05day  (1074) adult female 30day  (1281) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1739) embryo 02-04hr    1342 embryo 04-06hr  (2228) embryo 06-08hr  (2033) embryo 08-10hr  (1644) embryo 10-12hr  (1857) embryo 12-14hr    934 embryo 14-16hr    1109 embryo 16-18hr    917 embryo 18-20hr    916 embryo 20-22hr    892 embryo 22-24hr    857 larva L1    1252 larva L2    1164 larva L3 12hr old    894 larva L3 puffstage 1-2    934 larva L3 puffstage 3-6    893 larva L3 puffstage 7-9    895 white prepupae new    836 white prepupae 12hr    799 white prepupae 24hr    828 pupae 2d postWPP    838 pupae 3d postWPP    1084 pupae 4d postWPP    1105 adult male 01day  1458 adult male 05day  (1647) adult male 30day  (1655) adult female 01day    1300 adult female 05day    1074 adult female 30day    1281 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1739 embryo 02-04hr    1342 embryo 04-06hr    2228 embryo 06-08hr    2033 embryo 08-10hr    1644 embryo 10-12hr    1857 embryo 12-14hr    934 embryo 14-16hr    1109 embryo 16-18hr    917 embryo 18-20hr    916 embryo 20-22hr    892 embryo 22-24hr    857 larva L1    1252 larva L2    1164 larva L3 12hr old    894 larva L3 puffstage 1-2    934 larva L3 puffstage 3-6    893 larva L3 puffstage 7-9    895 white prepupae new    836 white prepupae 12hr    799 white prepupae 24hr    828 pupae 2d postWPP    838 pupae 3d postWPP    1084 pupae 4d postWPP    1105 adult male 01day    1458 adult male 05day    1647 adult male 30day    1655 adult female 01day    1300 adult female 05day    1074 adult female 30day    1281 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1739 embryo 02-04hr    1342 embryo 04-06hr    2228 embryo 06-08hr    2033 embryo 08-10hr    1644 embryo 10-12hr    1857 embryo 12-14hr    934 embryo 14-16hr    1109 embryo 16-18hr    917 embryo 18-20hr    916 embryo 20-22hr    892 embryo 22-24hr    857 larva L1    1252 larva L2    1164 larva L3 12hr old    894 larva L3 puffstage 1-2    934 larva L3 puffstage 3-6    893 larva L3 puffstage 7-9    895 white prepupae new    836 white prepupae 12hr    799 white prepupae 24hr    828 pupae 2d postWPP    838 pupae 3d postWPP    1084 pupae 4d postWPP    1105 adult male 01day    1458 adult male 05day    1647 adult male 30day    1655 adult female 01day    1300 adult female 05day    1074 adult female 30day    1281 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0027564 expression level Developmental Stage   Expression Level embryo 00-02hr    1739 embryo 02-04hr    1342 embryo 04-06hr    2228 embryo 06-08hr    2033 embryo 08-10hr    1644 embryo 10-12hr    1857 embryo 12-14hr    934 embryo 14-16hr    1109 embryo 16-18hr    917 embryo 18-20hr    916 embryo 20-22hr    892 embryo 22-24hr    857 larva L1    1252 larva L2    1164 larva L3 12hr old    894 larva L3 puffstage 1-2    934 larva L3 puffstage 3-6    893 larva L3 puffstage 7-9    895 white prepupae new    836 white prepupae 12hr    799 white prepupae 24hr    828 pupae 2d postWPP    838 pupae 3d postWPP    1084 pupae 4d postWPP    1105 adult male 01day    1458 adult male 05day    1647 adult male 30day    1655 adult female 01day    1300 adult female 05day    1074 adult female 30day    1281 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1739) embryo 02-04hr  (1342) embryo 04-06hr  (2228) embryo 06-08hr  (2033) embryo 08-10hr  (1644) embryo 10-12hr  (1857) embryo 12-14hr  (934) embryo 14-16hr  (1109) embryo 16-18hr  (917) embryo 18-20hr  (916) embryo 20-22hr  (892) embryo 22-24hr  (857) larva L1  (1252) larva L2  (1164) larva L3 12hr old  (894) larva L3 puffstage 1-2  (934) larva L3 puffstage 3-6  (893) larva L3 puffstage 7-9  (895) white prepupae new  (836) white prepupae 12hr  (799) white prepupae 24hr  (828) pupae 2d postWPP  (838) pupae 3d postWPP  (1084) pupae 4d postWPP  (1105) adult male 01day  (1458) adult male 05day  (1647) adult male 30day  (1655) adult female 01day  (1300) adult female 05day  (1074) adult female 30day  (1281) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  1739 embryo 02-04hr    1342 embryo 04-06hr  2228 embryo 06-08hr  2033 embryo 08-10hr  1644 embryo 10-12hr  1857 embryo 12-14hr    934 embryo 14-16hr    1109 embryo 16-18hr    917 embryo 18-20hr    916 embryo 20-22hr    892 embryo 22-24hr    857 larva L1    1252 larva L2    1164 larva L3 12hr old    894 larva L3 puffstage 1-2    934 larva L3 puffstage 3-6    893 larva L3 puffstage 7-9    895 white prepupae new    836 white prepupae 12hr    799 white prepupae 24hr    828 pupae 2d postWPP    838 pupae 3d postWPP    1084 pupae 4d postWPP    1105 adult male 01day  1458 adult male 05day  1647 adult male 30day  1655 adult female 01day    1300 adult female 05day    1074 adult female 30day    1281 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1739 embryo 02-04hr    1342 embryo 04-06hr    2228 embryo 06-08hr    2033 embryo 08-10hr    1644 embryo 10-12hr    1857 embryo 12-14hr    934 embryo 14-16hr    1109 embryo 16-18hr    917 embryo 18-20hr    916 embryo 20-22hr    892 embryo 22-24hr    857 larva L1    1252 larva L2    1164 larva L3 12hr old    894 larva L3 puffstage 1-2    934 larva L3 puffstage 3-6    893 larva L3 puffstage 7-9    895 white prepupae new    836 white prepupae 12hr    799 white prepupae 24hr    828 pupae 2d postWPP    838 pupae 3d postWPP    1084 pupae 4d postWPP    1105 adult male 01day    1458 adult male 05day    1647 adult male 30day    1655 adult female 01day    1300 adult female 05day    1074 adult female 30day    1281 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1739 embryo 02-04hr    1342 embryo 04-06hr    2228 embryo 06-08hr    2033 embryo 08-10hr    1644 embryo 10-12hr    1857 embryo 12-14hr    934 embryo 14-16hr    1109 embryo 16-18hr    917 embryo 18-20hr    916 embryo 20-22hr    892 embryo 22-24hr    857 larva L1    1252 larva L2    1164 larva L3 12hr old    894 larva L3 puffstage 1-2    934 larva L3 puffstage 3-6    893 larva L3 puffstage 7-9    895 white prepupae new    836 white prepupae 12hr    799 white prepupae 24hr    828 pupae 2d postWPP    838 pupae 3d postWPP    1084 pupae 4d postWPP    1105 adult male 01day    1458 adult male 05day    1647 adult male 30day    1655 adult female 01day    1300 adult female 05day    1074 adult female 30day    1281 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0027564    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0027564 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, adult spermathecae, adult male accessory gland, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0027564 expression level Tissue   Expression Level Larval Central Nervous System    83.275 Larval Midgut    199.7 Larval Hindgut    106.3 Larval Malpighian Tubules    185.2 Larval Fat Body    118.1 Larval Salivary Gland    193.2 Larval Trachea    64.125 Larval Carcass    89.5 Adult Head    85.9 Adult Eye    71.75 Adult Brain    146.7 Adult Thoracic-Abdominal Ganglion    185 Adult Crop    88.9 Adult Midgut    226.4 Adult Hindgut    124.9 Adult Malpighian Tubules    269.8 Adult Fat Body    112.8 Adult Salivary Gland    285.4 Adult Heart    105.525 Adult VirginFemale Spermatheca    129.2 Adult InseminatedFemale Spermatheca    154.1 Adult Ovary    76.4 Adult Testis    72.6 Adult Male Accessory Gland    133.2 Adult Carcass    113.7 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    83.275 Larval Midgut    199.7 Larval Hindgut    106.3 Larval Malpighian Tubules    185.2 Larval Fat Body    118.1 Larval Salivary Gland    193.2 Larval Trachea    64.125 Larval Carcass    89.5 Adult Head    85.9 Adult Eye    71.75 Adult Brain    146.7 Adult Thoracic-Abdominal Ganglion    185 Adult Crop    88.9 Adult Midgut    226.4 Adult Hindgut    124.9 Adult Malpighian Tubules    269.8 Adult Fat Body    112.8 Adult Salivary Gland    285.4 Adult Heart    105.525 Adult VirginFemale Spermatheca    129.2 Adult InseminatedFemale Spermatheca    154.1 Adult Ovary    76.4 Adult Testis    72.6 Adult Male Accessory Gland    133.2 Adult Carcass    113.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    83.275 Larval Midgut    199.7 Larval Hindgut    106.3 Larval Malpighian Tubules    185.2 Larval Fat Body    118.1 Larval Salivary Gland    193.2 Larval Trachea    64.125 Larval Carcass    89.5 Adult Head    85.9 Adult Eye    71.75 Adult Brain    146.7 Adult Thoracic-Abdominal Ganglion    185 Adult Crop    88.9 Adult Midgut    226.4 Adult Hindgut    124.9 Adult Malpighian Tubules    269.8 Adult Fat Body    112.8 Adult Salivary Gland    285.4 Adult Heart    105.525 Adult VirginFemale Spermatheca    129.2 Adult InseminatedFemale Spermatheca    154.1 Adult Ovary    76.4 Adult Testis    72.6 Adult Male Accessory Gland    133.2 Adult Carcass    113.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    83.275 Larval Midgut    199.7 Larval Hindgut    106.3 Larval Malpighian Tubules    185.2 Larval Fat Body    118.1 Larval Salivary Gland    193.2 Larval Trachea    64.125 Larval Carcass    89.5 Adult Head    85.9 Adult Eye    71.75 Adult Brain    146.7 Adult Thoracic-Abdominal Ganglion    185 Adult Crop    88.9 Adult Midgut    226.4 Adult Hindgut    124.9 Adult Malpighian Tubules    269.8 Adult Fat Body    112.8 Adult Salivary Gland    285.4 Adult Heart    105.525 Adult VirginFemale Spermatheca    129.2 Adult InseminatedFemale Spermatheca    154.1 Adult Ovary    76.4 Adult Testis    72.6 Adult Male Accessory Gland    133.2 Adult Carcass    113.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0027564 expression level Tissue   Expression Level Larval Central Nervous System    83.275 Larval Midgut    199.7 Larval Hindgut    106.3 Larval Malpighian Tubules    185.2 Larval Fat Body    118.1 Larval Salivary Gland    193.2 Larval Trachea    64.125 Larval Carcass    89.5 Adult Head    85.9 Adult Eye    71.75 Adult Brain    146.7 Adult Thoracic-Abdominal Ganglion    185 Adult Crop    88.9 Adult Midgut    226.4 Adult Hindgut    124.9 Adult Malpighian Tubules    269.8 Adult Fat Body    112.8 Adult Salivary Gland    285.4 Adult Heart    105.525 Adult VirginFemale Spermatheca    129.2 Adult InseminatedFemale Spermatheca    154.1 Adult Ovary    76.4 Adult Testis    72.6 Adult Male Accessory Gland    133.2 Adult Carcass    113.7 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    83.275 Larval Midgut    199.7 Larval Hindgut    106.3 Larval Malpighian Tubules    185.2 Larval Fat Body    118.1 Larval Salivary Gland    193.2 Larval Trachea    64.125 Larval Carcass    89.5 Adult Head    85.9 Adult Eye    71.75 Adult Brain    146.7 Adult Thoracic-Abdominal Ganglion    185 Adult Crop    88.9 Adult Midgut    226.4 Adult Hindgut    124.9 Adult Malpighian Tubules    269.8 Adult Fat Body    112.8 Adult Salivary Gland    285.4 Adult Heart    105.525 Adult VirginFemale Spermatheca    129.2 Adult InseminatedFemale Spermatheca    154.1 Adult Ovary    76.4 Adult Testis    72.6 Adult Male Accessory Gland    133.2 Adult Carcass    113.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    83.275 Larval Midgut    199.7 Larval Hindgut    106.3 Larval Malpighian Tubules    185.2 Larval Fat Body    118.1 Larval Salivary Gland    193.2 Larval Trachea    64.125 Larval Carcass    89.5 Adult Head    85.9 Adult Eye    71.75 Adult Brain    146.7 Adult Thoracic-Abdominal Ganglion    185 Adult Crop    88.9 Adult Midgut    226.4 Adult Hindgut    124.9 Adult Malpighian Tubules    269.8 Adult Fat Body    112.8 Adult Salivary Gland    285.4 Adult Heart    105.525 Adult VirginFemale Spermatheca    129.2 Adult InseminatedFemale Spermatheca    154.1 Adult Ovary    76.4 Adult Testis    72.6 Adult Male Accessory Gland    133.2 Adult Carcass    113.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    83.275 Larval Midgut    199.7 Larval Hindgut    106.3 Larval Malpighian Tubules    185.2 Larval Fat Body    118.1 Larval Salivary Gland    193.2 Larval Trachea    64.125 Larval Carcass    89.5 Adult Head    85.9 Adult Eye    71.75 Adult Brain    146.7 Adult Thoracic-Abdominal Ganglion    185 Adult Crop    88.9 Adult Midgut    226.4 Adult Hindgut    124.9 Adult Malpighian Tubules    269.8 Adult Fat Body    112.8 Adult Salivary Gland    285.4 Adult Heart    105.525 Adult VirginFemale Spermatheca    129.2 Adult InseminatedFemale Spermatheca    154.1 Adult Ovary    76.4 Adult Testis    72.6 Adult Male Accessory Gland    133.2 Adult Carcass    113.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    85.9   NA  Eye    71.75   NA  Brain    146.7   83.275  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    185   NA  Crop    88.9   199.7  Midgut    226.4   106.3  Hindgut    124.9   185.2  Malpighian Tubules    269.8   118.1  Fat Body    112.8   193.2  Salivary Gland    285.4   NA  Heart    105.525   64.125  Trachea    NA   NA  VirginFemale Spermatheca    129.2   NA  InseminatedFemale Spermatheca    154.1   NA  Ovary    76.4   NA  Testis    72.6   NA  Male Accessory Gland    133.2   89.5  Carcass    113.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_31
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0027564 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3149-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG3149 Class Mutagen Stocks Known lesion CG3149HP10509 1 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG3149 Class Mutagen Stocks Known lesion CG3149GD3241 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes
Aneuploid Aberrations
Disrupted in	Df(1)Exel6236 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD3241} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPg}CG3149HP10509 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
lipid transporter activity inferred from electronic annotation with InterPro:IPR007594 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
lipid transport inferred from electronic annotation with InterPro:IPR007594 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR007594 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG3149 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 57991 DroID - A comprehensive database of gene and protein interactions. • FBgn0027564 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31489
Orthologs
Genome-wide drosophilid orthologs	Dana\GF22446 Dere\GG18478 Dgri\GH12413 Dmoj\GI15868 Dper\GL19911 Dpse\GA16280 Dsec\GM12626 Dsim\GD16242 Dvir\GJ19026 Dwil\GK25490 Dyak\GE16795
Curated drosophilid orthologs	Dpse\GA16280
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL013393-PA Aedes aegypti (mosquito) AGAP004419-PA Anopheles gambiae (mosquito) XP_395946.2 Apis mellifera (honey bee) XP_001944399.1 Acyrthosiphon pisum (pea aphid) At5g07630.1 Arabidopsis thaliana (wall cress) 27371 Batrachochytrium dendrobatidis (chytrid fungus) 124156 Branchiostoma floridae (lancelet) BGIBMGA005329-PA Bombyx mori (silk worm) CAL0000084 Candida albicans (a form of yeast) CN26195 Caenorhabditis brenneri (small nematode) CBP14240 Caenorhabditis briggsae (nematode) CE07621 Caenorhabditis elegans (worm) ENSCAFP00000012844 Canis familiaris (dog) CAGL0J04378g Candida glabrata (haploid yeast) Chro.60537 Cryptosporidium hominis (obligate parasite) ENSCINP00000003576 Ciona intestinalis (sea squirt) JA10108 Caenorhabditis japonica (nematode) cn02366 Cryptococcus neoformans (yeast-like fungus) cgd6_4680 Cryptosporidium parvum (protozoan parasite) CPIJ006240 Culex pipens (mosquito) ENSCPOP00000009690 Cavia porcellus (guinea pig) RP22991 Caenorhabditis remanei (nematode) RP49305 Caenorhabditis remanei (nematode) ENSCSAVP00000004674 Ciona savignyi (sedentary tunicate) 96530 Capitella spl (polychaete worm) DDB0187956 Dictyostelium discoideum (amoeba) DEHA2F21318g Debaryomyces Hansenii (yeast) 306088 Daphnia pulex (daphnia) ENSDARP00000079496 Danio rerio (zebra fish) ENSECAP00000020512 Equus caballus (horse) XP_657428 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000001010 Gymnopilus aculeatus (mushroom) ENSGALP00000003006 Gallus gallus (chicken) 90783 Hypsipyla robusta (cedar shoot borer) ENSP00000296292 Homo sapiens (human) ISCW023542-PA Ixodes scapularis (deer tick) KLLA0E10451g Kluyveromyces lactis (yeast) 234090 Lottia gigantea (owl limpet) 22469 Monocosta brevicollis (choanoflagellate) ENSMODP00000013349 Monodelphis domestica (gray opossum) ENSMMUP00000021282 Macaca mulatta (rhesus monkey) ENSMUSP00000064153 Mus musculus (house mouse) 104237 Nematostella vectensis (starlet anemone) XP_001605141.1 Nasonia vitripennis (wasp) ENSORLP00000001742 Oryzias latipes (japanese killifish) 32206 Ostreococcus tauri (green alga) PHUM004316-PA Pediculus humanus (human body louse) PP02554 Pristionchus pacificus (nematode) 117127 Physcomitrella patens (moss) ENSPPYP00000015430 Pongo pygmaeus (orangutan) 79049 Phytophthora ramorum (sudden oak death pathogen) 142530 Phytophthora sojae (root rot pathogen) 423550 Populus trichocarpa (black cottonwood) ENSPTRP00000025951 Pan troglodytes (chimpanzee) ENSRNOP00000035354 Rattus norvegicus (norway rat) 4748986 Sorghum bicolor (sorghum) YBL020W Saccharomyces cerevisiae (budding yeast) Smp_131100 Schistosoma mansoni (trematode parasite) SPBC887.19 Schizosaccharomyces pombe (fission yeast) XP_975124.1 Tribolium castaneum (red flour beetle) Tc00.1047053503935.10 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000005808 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000026772 Takifugu rubripes (pufferfish Takifugu) 3806.m00233 Tetrahymena thermophila (ciliate protozoa) 83075.m00028 Trichomonas vaginalis (parasitic flagellated protozoan) 92669.m00017 Trichomonas vaginalis (parasitic flagellated protozoan) YALI0E06721g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV50728 NV16980 LH18231 ISCW023542 FBgn0234288 FBgn0227449 FBgn0206172 FBgn0187869 FBgn0167562 JGI_V11_306088 FBgn0076296 FBgn0157508 FBgn0138617 FBgn0119892 FBgn0110691 FBgn0099442 CPIJ006240 BGIBMGA005329 ACYPI004121 GB14370 AGAP004419 AAEL013393 PB24700 GLEAN_05308
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	21878 w1118 P{EPg}CG3149HP10509
VDRC	v7073 w1118 P{GD3241}v7073 v47560 w1118; P{GD3241}v47560/TM3
Genomic Clones ( 2 )
	BACR27C07 BACR27J18 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 16 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH08388
Other clones	DPiM_GH08388
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LD06081 LD07664 LD35221 RE29536 RE33773 RE34646 SD05861 SD06370 SD10159
Other clones	CK01.58D.F3 EC053354 EC056254 EK291535 FGC029B01
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0027564 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31489
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: BcDNA:GH08388 CG3149 (Zhong, 1999.11)
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132018 RefSeq (Proteins) • NP_572246 DDBJ / EMBL / GenBank • AAD38624 AAF46064 AF145649 AI109255 AI402132 Entrez Gene - A searchable database of RefSeq genes. • 31489 UniProtKB/TrEMBL • Q9Y123
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • RFT1 (IPR007594)
Linkouts
	BioGRID - A database of protein and genetic interactions • 57991 DroID - A comprehensive database of gene and protein interactions. • FBgn0027564 DRSC - Results from RNAi screens. • FBgn0027564 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0027564 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3149-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0027564 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31489 InParanoid A subset of ortholog calls from InParanoid. • AAEL013393-PA Aedes aegypti (mosquito) AGAP004419-PA Anopheles gambiae (mosquito) XP_395946.2 Apis mellifera (honey bee) XP_001944399.1 Acyrthosiphon pisum (pea aphid) At5g07630.1 Arabidopsis thaliana (wall cress) 27371 Batrachochytrium dendrobatidis (chytrid fungus) 124156 Branchiostoma floridae (lancelet) BGIBMGA005329-PA Bombyx mori (silk worm) CAL0000084 Candida albicans (a form of yeast) CN26195 Caenorhabditis brenneri (small nematode) CBP14240 Caenorhabditis briggsae (nematode) CE07621 Caenorhabditis elegans (worm) ENSCAFP00000012844 Canis familiaris (dog) CAGL0J04378g Candida glabrata (haploid yeast) Chro.60537 Cryptosporidium hominis (obligate parasite) ENSCINP00000003576 Ciona intestinalis (sea squirt) JA10108 Caenorhabditis japonica (nematode) cn02366 Cryptococcus neoformans (yeast-like fungus) cgd6_4680 Cryptosporidium parvum (protozoan parasite) CPIJ006240 Culex pipens (mosquito) ENSCPOP00000009690 Cavia porcellus (guinea pig) RP22991 Caenorhabditis remanei (nematode) RP49305 Caenorhabditis remanei (nematode) ENSCSAVP00000004674 Ciona savignyi (sedentary tunicate) 96530 Capitella spl (polychaete worm) DDB0187956 Dictyostelium discoideum (amoeba) DEHA2F21318g Debaryomyces Hansenii (yeast) 306088 Daphnia pulex (daphnia) ENSDARP00000079496 Danio rerio (zebra fish) ENSECAP00000020512 Equus caballus (horse) XP_657428 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000001010 Gymnopilus aculeatus (mushroom) ENSGALP00000003006 Gallus gallus (chicken) 90783 Hypsipyla robusta (cedar shoot borer) ENSP00000296292 Homo sapiens (human) ISCW023542-PA Ixodes scapularis (deer tick) KLLA0E10451g Kluyveromyces lactis (yeast) 234090 Lottia gigantea (owl limpet) 22469 Monocosta brevicollis (choanoflagellate) ENSMODP00000013349 Monodelphis domestica (gray opossum) ENSMMUP00000021282 Macaca mulatta (rhesus monkey) ENSMUSP00000064153 Mus musculus (house mouse) 104237 Nematostella vectensis (starlet anemone) XP_001605141.1 Nasonia vitripennis (wasp) ENSORLP00000001742 Oryzias latipes (japanese killifish) 32206 Ostreococcus tauri (green alga) PHUM004316-PA Pediculus humanus (human body louse) PP02554 Pristionchus pacificus (nematode) 117127 Physcomitrella patens (moss) ENSPPYP00000015430 Pongo pygmaeus (orangutan) 79049 Phytophthora ramorum (sudden oak death pathogen) 142530 Phytophthora sojae (root rot pathogen) 423550 Populus trichocarpa (black cottonwood) ENSPTRP00000025951 Pan troglodytes (chimpanzee) ENSRNOP00000035354 Rattus norvegicus (norway rat) 4748986 Sorghum bicolor (sorghum) YBL020W Saccharomyces cerevisiae (budding yeast) Smp_131100 Schistosoma mansoni (trematode parasite) SPBC887.19 Schizosaccharomyces pombe (fission yeast) XP_975124.1 Tribolium castaneum (red flour beetle) Tc00.1047053503935.10 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000005808 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000026772 Takifugu rubripes (pufferfish Takifugu) 3806.m00233 Tetrahymena thermophila (ciliate protozoa) 83075.m00028 Trichomonas vaginalis (parasitic flagellated protozoan) 92669.m00017 Trichomonas vaginalis (parasitic flagellated protozoan) YALI0E06721g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31489 modMine - Data generated by the modENCODE project. • FBgn0027564 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV50728 NV16980 LH18231 ISCW023542 FBgn0234288 FBgn0227449 FBgn0206172 FBgn0187869 FBgn0167562 JGI_V11_306088 FBgn0076296 FBgn0157508 FBgn0138617 FBgn0119892 FBgn0110691 FBgn0099442 CPIJ006240 BGIBMGA005329 ACYPI004121 GB14370 AGAP004419 AAEL013393 PB24700 GLEAN_05308
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	BcDNA:GH08388 (Giot et al., 2003, ) CG3149 (Ramos et al., 2006)
Name Synonym
Secondary FlyBase IDs
References ( 15 )
Research paper	Ramos et al., 2006, Genetics 172(4): 2337--2349 Genomic organization of gypsy chromatin insulators in Drosophila melanogaster. [FBrf0190762] Shimmi et al., 2005, Dev. Biol. 282(1): 70--83 The crossveinless gene encodes a new member of the Twisted gastrulation family of BMP-binding proteins which, with Short gastrulation, promotes BMP signaling in the crossveins of the Drosophila wing. [FBrf0187398] Vilmos et al., 2005, EMBO Rpts 6(3): 262--267 crossveinless defines a new family of Twisted-gastrulation-like modulators of bone morphogenetic protein signalling. [FBrf0183951]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Vilmos, 2005, EMBO Rpts 6(3): 1--8 Supplementary Online Material. [FBrf0188586] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Matthews, 2008.4.15, DP and HP P-element insertions submitted to the Bloomington Drosophila Stock Center. DP and HP P-element insertions submitted to the Bloomington Drosophila Stock Center. [FBrf0204789] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Curated genome annotation	Heiman, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126693] Zhong, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126703]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]