Gene Dmel\CG17712

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General Information

Symbol

Dmel\CG17712

Species

D. melanogaster

Name

Annotation symbol

CG17712

Feature type

protein_coding_gene

FlyBase ID

FBgn0027597

Gene Model Status

Current

Stock availability

7 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

22B2-22B2

Sequence location

2L:1,750,687..1,752,122 [-]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG17712 (FBgn0027597). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: nucleotide binding; oxidoreductase activity. The biological processes in which it is involved are not known. 6 alleles are reported. The phenotype of these alleles is annotated with: trichogen cell. It has one annotated transcript and one annotated polypeptide. Protein features are: NAD(P)-binding domain; Oxidoreductase, N-terminal. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult salivary gland, adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1632626_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG17712. Gene sequence location is 2L:1750687..1752122.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

22B2-22B2

Limits computationally determined from genome sequence between P{lacW}CG17646^k11021 and P{EP}EP366

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG17712 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.47

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG17712-RA

FBtr0077903

NM_134775

1436

384

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG17712-PA

FBpp0077569

42.6

384

8.37

NP_608619

AAF51339

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Oxidoreductase, N-terminal (IPR000683)

NAD(P)-binding domain (IPR016040)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q9Y153

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism | ubiquitous

(Fisher et al., 2012)

Comment:maternally deposited

embryonic stage 4 -- 6

organism

(Fisher et al., 2012)

Comment:rapidly degraded

organism | faint & ubiquitous

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | faint & ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

organism | faint & ubiquitous

(Fisher et al., 2012)

embryonic stage 11 -- 12

anterior midgut primordium

(Fisher et al., 2012)

organism | faint & ubiquitous

(Fisher et al., 2012)

posterior midgut primordium

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic/larval midgut

(Fisher et al., 2012)

organism | ubiquitous

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult salivary gland, adult ovary.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		93.35
Larval Midgut		41.7
Larval Hindgut		65.2
Larval Malpighian Tubules		97.7
Larval Fat Body		42.7
Larval Salivary Gland		209.3
Larval Trachea		66.825
Larval Carcass		55.9
Adult Head		53.1
Adult Eye		68.25
Adult Brain		98.9
Adult Thoracic-Abdominal Ganglion		85.3
Adult Crop		65.1
Adult Midgut		50.6
Adult Hindgut		74.9
Adult Malpighian Tubules		81.7
Adult Fat Body		27.9
Adult Salivary Gland		146.2
Adult Heart		36.575
Adult VirginFemale Spermatheca		30.3
Adult InseminatedFemale Spermatheca		35.6
Adult Ovary		156.8
Adult Testis		55.8
Adult Male Accessory Gland		69.9
Adult Carcass		34.3
Expression Level Scale		None Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		93.35
Larval Midgut		41.7
Larval Hindgut		65.2
Larval Malpighian Tubules		97.7
Larval Fat Body		42.7
Larval Salivary Gland		209.3
Larval Trachea		66.825
Larval Carcass		55.9
Adult Head		53.1
Adult Eye		68.25
Adult Brain		98.9
Adult Thoracic-Abdominal Ganglion		85.3
Adult Crop		65.1
Adult Midgut		50.6
Adult Hindgut		74.9
Adult Malpighian Tubules		81.7
Adult Fat Body		27.9
Adult Salivary Gland		146.2
Adult Heart		36.575
Adult VirginFemale Spermatheca		30.3
Adult InseminatedFemale Spermatheca		35.6
Adult Ovary		156.8
Adult Testis		55.8
Adult Male Accessory Gland		69.9
Adult Carcass		34.3
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		93.35
Larval Midgut		41.7
Larval Hindgut		65.2
Larval Malpighian Tubules		97.7
Larval Fat Body		42.7
Larval Salivary Gland		209.3
Larval Trachea		66.825
Larval Carcass		55.9
Adult Head		53.1
Adult Eye		68.25
Adult Brain		98.9
Adult Thoracic-Abdominal Ganglion		85.3
Adult Crop		65.1
Adult Midgut		50.6
Adult Hindgut		74.9
Adult Malpighian Tubules		81.7
Adult Fat Body		27.9
Adult Salivary Gland		146.2
Adult Heart		36.575
Adult VirginFemale Spermatheca		30.3
Adult InseminatedFemale Spermatheca		35.6
Adult Ovary		156.8
Adult Testis		55.8
Adult Male Accessory Gland		69.9
Adult Carcass		34.3
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		93.35
Larval Midgut		41.7
Larval Hindgut		65.2
Larval Malpighian Tubules		97.7
Larval Fat Body		42.7
Larval Salivary Gland		209.3
Larval Trachea		66.825
Larval Carcass		55.9
Adult Head		53.1
Adult Eye		68.25
Adult Brain		98.9
Adult Thoracic-Abdominal Ganglion		85.3
Adult Crop		65.1
Adult Midgut		50.6
Adult Hindgut		74.9
Adult Malpighian Tubules		81.7
Adult Fat Body		27.9
Adult Salivary Gland		146.2
Adult Heart		36.575
Adult VirginFemale Spermatheca		30.3
Adult InseminatedFemale Spermatheca		35.6
Adult Ovary		156.8
Adult Testis		55.8
Adult Male Accessory Gland		69.9
Adult Carcass		34.3
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		93.35
Larval Midgut		41.7
Larval Hindgut		65.2
Larval Malpighian Tubules		97.7
Larval Fat Body		42.7
Larval Salivary Gland		209.3
Larval Trachea		66.825
Larval Carcass		55.9
Adult Head		53.1
Adult Eye		68.25
Adult Brain		98.9
Adult Thoracic-Abdominal Ganglion		85.3
Adult Crop		65.1
Adult Midgut		50.6
Adult Hindgut		74.9
Adult Malpighian Tubules		81.7
Adult Fat Body		27.9
Adult Salivary Gland		146.2
Adult Heart		36.575
Adult VirginFemale Spermatheca		30.3
Adult InseminatedFemale Spermatheca		35.6
Adult Ovary		156.8
Adult Testis		55.8
Adult Male Accessory Gland		69.9
Adult Carcass		34.3
Expression Level Scale		None Low Moderate

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		93.35
Larval Midgut		41.7
Larval Hindgut		65.2
Larval Malpighian Tubules		97.7
Larval Fat Body		42.7
Larval Salivary Gland		209.3
Larval Trachea		66.825
Larval Carcass		55.9
Adult Head		53.1
Adult Eye		68.25
Adult Brain		98.9
Adult Thoracic-Abdominal Ganglion		85.3
Adult Crop		65.1
Adult Midgut		50.6
Adult Hindgut		74.9
Adult Malpighian Tubules		81.7
Adult Fat Body		27.9
Adult Salivary Gland		146.2
Adult Heart		36.575
Adult VirginFemale Spermatheca		30.3
Adult InseminatedFemale Spermatheca		35.6
Adult Ovary		156.8
Adult Testis		55.8
Adult Male Accessory Gland		69.9
Adult Carcass		34.3
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		93.35
Larval Midgut		41.7
Larval Hindgut		65.2
Larval Malpighian Tubules		97.7
Larval Fat Body		42.7
Larval Salivary Gland		209.3
Larval Trachea		66.825
Larval Carcass		55.9
Adult Head		53.1
Adult Eye		68.25
Adult Brain		98.9
Adult Thoracic-Abdominal Ganglion		85.3
Adult Crop		65.1
Adult Midgut		50.6
Adult Hindgut		74.9
Adult Malpighian Tubules		81.7
Adult Fat Body		27.9
Adult Salivary Gland		146.2
Adult Heart		36.575
Adult VirginFemale Spermatheca		30.3
Adult InseminatedFemale Spermatheca		35.6
Adult Ovary		156.8
Adult Testis		55.8
Adult Male Accessory Gland		69.9
Adult Carcass		34.3
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		93.35
Larval Midgut		41.7
Larval Hindgut		65.2
Larval Malpighian Tubules		97.7
Larval Fat Body		42.7
Larval Salivary Gland		209.3
Larval Trachea		66.825
Larval Carcass		55.9
Adult Head		53.1
Adult Eye		68.25
Adult Brain		98.9
Adult Thoracic-Abdominal Ganglion		85.3
Adult Crop		65.1
Adult Midgut		50.6
Adult Hindgut		74.9
Adult Malpighian Tubules		81.7
Adult Fat Body		27.9
Adult Salivary Gland		146.2
Adult Heart		36.575
Adult VirginFemale Spermatheca		30.3
Adult InseminatedFemale Spermatheca		35.6
Adult Ovary		156.8
Adult Testis		55.8
Adult Male Accessory Gland		69.9
Adult Carcass		34.3
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	53.1
NA	Eye	68.25
NA	Brain	98.9
93.35	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	85.3
NA	Crop	65.1
41.7	Midgut	50.6
65.2	Hindgut	74.9
97.7	Malpighian Tubules	81.7
42.7	Fat Body	27.9
209.3	Salivary Gland	146.2
NA	Heart	36.575
66.825	Trachea	NA
NA	VirginFemale Spermatheca	30.3
NA	InseminatedFemale Spermatheca	35.6
NA	Ovary	156.8
NA	Testis	55.8
NA	Male Accessory Gland	69.9
55.9	Carcass	34.3

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		10
central nervous system, larvae L3		8
central nervous system, pupae P8		6
head, virgin 1-day female		3
head, virgin 4-day female		3
head, virgin 20-day female		4
head, mated 1-day female		3
head, mated 4-day female		3
head, mated 20-day female		3
head, mated 1-day male		6
head, mated 4-day male		4
head, mated 20-day male		5
salivary gland, larvae L3 wandering		11
salivary gland, white prepupae		8
digestive system, larvae L3 wandering		7
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		3
fat body, larvae L3 wandering		1
fat body, white prepupae		4
fat body, pupae P8		15
carcass, larvae L3 wandering		7
carcass, 1-day adult		2
carcass, 4-day adult		2
carcass, 20-day adult		2
ovary, virgin 4-day female		15
ovary, mated 4-day female		10
testis, mated 4-day male		13
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		10
central nervous system, larvae L3		8
central nervous system, pupae P8		6
head, virgin 1-day female		3
head, virgin 4-day female		3
head, virgin 20-day female		4
head, mated 1-day female		3
head, mated 4-day female		3
head, mated 20-day female		3
head, mated 1-day male		6
head, mated 4-day male		4
head, mated 20-day male		5
salivary gland, larvae L3 wandering		11
salivary gland, white prepupae		8
digestive system, larvae L3 wandering		7
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		3
fat body, larvae L3 wandering		1
fat body, white prepupae		4
fat body, pupae P8		15
carcass, larvae L3 wandering		7
carcass, 1-day adult		2
carcass, 4-day adult		2
carcass, 20-day adult		2
ovary, virgin 4-day female		15
ovary, mated 4-day female		10
testis, mated 4-day male		13
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		10
central nervous system, larvae L3		8
central nervous system, pupae P8		6
head, virgin 1-day female		3
head, virgin 4-day female		3
head, virgin 20-day female		4
head, mated 1-day female		3
head, mated 4-day female		3
head, mated 20-day female		3
head, mated 1-day male		6
head, mated 4-day male		4
head, mated 20-day male		5
salivary gland, larvae L3 wandering		11
salivary gland, white prepupae		8
digestive system, larvae L3 wandering		7
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		3
fat body, larvae L3 wandering		1
fat body, white prepupae		4
fat body, pupae P8		15
carcass, larvae L3 wandering		7
carcass, 1-day adult		2
carcass, 4-day adult		2
carcass, 20-day adult		2
ovary, virgin 4-day female		15
ovary, mated 4-day female		10
testis, mated 4-day male		13
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		10
central nervous system, larvae L3		8
central nervous system, pupae P8		6
head, virgin 1-day female		3
head, virgin 4-day female		3
head, virgin 20-day female		4
head, mated 1-day female		3
head, mated 4-day female		3
head, mated 20-day female		3
head, mated 1-day male		6
head, mated 4-day male		4
head, mated 20-day male		5
salivary gland, larvae L3 wandering		11
salivary gland, white prepupae		8
digestive system, larvae L3 wandering		7
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		3
fat body, larvae L3 wandering		1
fat body, white prepupae		4
fat body, pupae P8		15
carcass, larvae L3 wandering		7
carcass, 1-day adult		2
carcass, 4-day adult		2
carcass, 20-day adult		2
ovary, virgin 4-day female		15
ovary, mated 4-day female		10
testis, mated 4-day male		13
accessory gland, mated 4-day male		2
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		10
central nervous system, larvae L3		8
central nervous system, pupae P8		6
head, virgin 1-day female		3
head, virgin 4-day female		3
head, virgin 20-day female		4
head, mated 1-day female		3
head, mated 4-day female		3
head, mated 20-day female		3
head, mated 1-day male		6
head, mated 4-day male		4
head, mated 20-day male		5
salivary gland, larvae L3 wandering		11
salivary gland, white prepupae		8
digestive system, larvae L3 wandering		7
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		3
fat body, larvae L3 wandering		1
fat body, white prepupae		4
fat body, pupae P8		15
carcass, larvae L3 wandering		7
carcass, 1-day adult		2
carcass, 4-day adult		2
carcass, 20-day adult		2
ovary, virgin 4-day female		15
ovary, mated 4-day female		10
testis, mated 4-day male		13
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		10
central nervous system, larvae L3		8
central nervous system, pupae P8		6
head, virgin 1-day female		3
head, virgin 4-day female		3
head, virgin 20-day female		4
head, mated 1-day female		3
head, mated 4-day female		3
head, mated 20-day female		3
head, mated 1-day male		6
head, mated 4-day male		4
head, mated 20-day male		5
salivary gland, larvae L3 wandering		11
salivary gland, white prepupae		8
digestive system, larvae L3 wandering		7
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		3
fat body, larvae L3 wandering		1
fat body, white prepupae		4
fat body, pupae P8		15
carcass, larvae L3 wandering		7
carcass, 1-day adult		2
carcass, 4-day adult		2
carcass, 20-day adult		2
ovary, virgin 4-day female		15
ovary, mated 4-day female		10
testis, mated 4-day male		13
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		10
central nervous system, larvae L3		8
central nervous system, pupae P8		6
head, virgin 1-day female		3
head, virgin 4-day female		3
head, virgin 20-day female		4
head, mated 1-day female		3
head, mated 4-day female		3
head, mated 20-day female		3
head, mated 1-day male		6
head, mated 4-day male		4
head, mated 20-day male		5
salivary gland, larvae L3 wandering		11
salivary gland, white prepupae		8
digestive system, larvae L3 wandering		7
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		3
fat body, larvae L3 wandering		1
fat body, white prepupae		4
fat body, pupae P8		15
carcass, larvae L3 wandering		7
carcass, 1-day adult		2
carcass, 4-day adult		2
carcass, 20-day adult		2
ovary, virgin 4-day female		15
ovary, mated 4-day female		10
testis, mated 4-day male		13
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		10
central nervous system, larvae L3		8
central nervous system, pupae P8		6
head, virgin 1-day female		3
head, virgin 4-day female		3
head, virgin 20-day female		4
head, mated 1-day female		3
head, mated 4-day female		3
head, mated 20-day female		3
head, mated 1-day male		6
head, mated 4-day male		4
head, mated 20-day male		5
salivary gland, larvae L3 wandering		11
salivary gland, white prepupae		8
digestive system, larvae L3 wandering		7
digestive system, 1-day adult		4
digestive system, 4-day adult		4
digestive system, 20-day adult		3
fat body, larvae L3 wandering		1
fat body, white prepupae		4
fat body, pupae P8		15
carcass, larvae L3 wandering		7
carcass, 1-day adult		2
carcass, 4-day adult		2
carcass, 20-day adult		2
ovary, virgin 4-day female		15
ovary, mated 4-day female		10
testis, mated 4-day male		13
accessory gland, mated 4-day male		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 00-18 hour embryonic stages, at stages throughout the pupal period, in adult female stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		30
embryo 02-04hr		9
embryo 04-06hr		27
embryo 06-08hr		30
embryo 08-10hr		29
embryo 10-12hr		43
embryo 12-14hr		24
embryo 14-16hr		21
embryo 16-18hr		16
embryo 18-20hr		12
embryo 20-22hr		10
embryo 22-24hr		10
larva L1		9
larva L2		10
larva L3 12hr old		6
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		13
larva L3 puffstage 7-9		17
white prepupae new		17
white prepupae 12hr		16
white prepupae 24hr		20
pupae 2d postWPP		20
pupae 3d postWPP		11
pupae 4d postWPP		10
adult male 01day		8
adult male 05day		11
adult male 30day		10
adult female 01day		13
adult female 05day		24
adult female 30day		26
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(30)
embryo 02-04hr		9
embryo 04-06hr		(27)
embryo 06-08hr		(30)
embryo 08-10hr		(29)
embryo 10-12hr		(43)
embryo 12-14hr		24
embryo 14-16hr		21
embryo 16-18hr		16
embryo 18-20hr		12
embryo 20-22hr		10
embryo 22-24hr		10
larva L1		9
larva L2		10
larva L3 12hr old		6
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		13
larva L3 puffstage 7-9		17
white prepupae new		17
white prepupae 12hr		16
white prepupae 24hr		20
pupae 2d postWPP		20
pupae 3d postWPP		11
pupae 4d postWPP		10
adult male 01day		8
adult male 05day		11
adult male 30day		10
adult female 01day		13
adult female 05day		24
adult female 30day		26
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		30
embryo 02-04hr		9
embryo 04-06hr		27
embryo 06-08hr		30
embryo 08-10hr		29
embryo 10-12hr		43
embryo 12-14hr		24
embryo 14-16hr		21
embryo 16-18hr		16
embryo 18-20hr		12
embryo 20-22hr		10
embryo 22-24hr		10
larva L1		9
larva L2		10
larva L3 12hr old		6
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		13
larva L3 puffstage 7-9		17
white prepupae new		17
white prepupae 12hr		16
white prepupae 24hr		20
pupae 2d postWPP		20
pupae 3d postWPP		11
pupae 4d postWPP		10
adult male 01day		8
adult male 05day		11
adult male 30day		10
adult female 01day		13
adult female 05day		24
adult female 30day		26
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		30
embryo 02-04hr		9
embryo 04-06hr		27
embryo 06-08hr		30
embryo 08-10hr		29
embryo 10-12hr		43
embryo 12-14hr		24
embryo 14-16hr		21
embryo 16-18hr		16
embryo 18-20hr		12
embryo 20-22hr		10
embryo 22-24hr		10
larva L1		9
larva L2		10
larva L3 12hr old		6
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		13
larva L3 puffstage 7-9		17
white prepupae new		17
white prepupae 12hr		16
white prepupae 24hr		20
pupae 2d postWPP		20
pupae 3d postWPP		11
pupae 4d postWPP		10
adult male 01day		8
adult male 05day		11
adult male 30day		10
adult female 01day		13
adult female 05day		24
adult female 30day		26
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		30
embryo 02-04hr		9
embryo 04-06hr		27
embryo 06-08hr		30
embryo 08-10hr		29
embryo 10-12hr		43
embryo 12-14hr		24
embryo 14-16hr		21
embryo 16-18hr		16
embryo 18-20hr		12
embryo 20-22hr		10
embryo 22-24hr		10
larva L1		9
larva L2		10
larva L3 12hr old		6
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		13
larva L3 puffstage 7-9		17
white prepupae new		17
white prepupae 12hr		16
white prepupae 24hr		20
pupae 2d postWPP		20
pupae 3d postWPP		11
pupae 4d postWPP		10
adult male 01day		8
adult male 05day		11
adult male 30day		10
adult female 01day		13
adult female 05day		24
adult female 30day		26
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		30
embryo 02-04hr		9
embryo 04-06hr		27
embryo 06-08hr		30
embryo 08-10hr		29
embryo 10-12hr		(43)
embryo 12-14hr		24
embryo 14-16hr		21
embryo 16-18hr		16
embryo 18-20hr		12
embryo 20-22hr		10
embryo 22-24hr		10
larva L1		9
larva L2		10
larva L3 12hr old		6
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		13
larva L3 puffstage 7-9		17
white prepupae new		17
white prepupae 12hr		16
white prepupae 24hr		20
pupae 2d postWPP		20
pupae 3d postWPP		11
pupae 4d postWPP		10
adult male 01day		8
adult male 05day		11
adult male 30day		10
adult female 01day		13
adult female 05day		24
adult female 30day		26
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		30
embryo 02-04hr		9
embryo 04-06hr		27
embryo 06-08hr		30
embryo 08-10hr		29
embryo 10-12hr		43
embryo 12-14hr		24
embryo 14-16hr		21
embryo 16-18hr		16
embryo 18-20hr		12
embryo 20-22hr		10
embryo 22-24hr		10
larva L1		9
larva L2		10
larva L3 12hr old		6
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		13
larva L3 puffstage 7-9		17
white prepupae new		17
white prepupae 12hr		16
white prepupae 24hr		20
pupae 2d postWPP		20
pupae 3d postWPP		11
pupae 4d postWPP		10
adult male 01day		8
adult male 05day		11
adult male 30day		10
adult female 01day		13
adult female 05day		24
adult female 30day		26
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		30
embryo 02-04hr		9
embryo 04-06hr		27
embryo 06-08hr		30
embryo 08-10hr		29
embryo 10-12hr		43
embryo 12-14hr		24
embryo 14-16hr		21
embryo 16-18hr		16
embryo 18-20hr		12
embryo 20-22hr		10
embryo 22-24hr		10
larva L1		9
larva L2		10
larva L3 12hr old		6
larva L3 puffstage 1-2		9
larva L3 puffstage 3-6		13
larva L3 puffstage 7-9		17
white prepupae new		17
white prepupae 12hr		16
white prepupae 24hr		20
pupae 2d postWPP		20
pupae 3d postWPP		11
pupae 4d postWPP		10
adult male 01day		8
adult male 05day		11
adult male 30day		10
adult female 01day		13
adult female 05day		24
adult female 30day		26
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		20
Schneider line 2 Sg4		16
embryonic 1182-4H		7
embryonic GM2		8
embryonic Kc167		12
embryonic S1		16
embryonic S3		6
leg disc CME L1		9
wing disc CME-W2		6
wing disc ML-DmD8		10
wing disc ML-DmD9		8
wing disc ML-DmD16-c3		12
wing disc ML-DmD21		13
wing disc ML-DmD32		10
haltere disc ML-DmD17-c3		10
eye-antennal disc ML-DmD11		11
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		12
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		14
tumorous blood cells mbn2		6
ovary fGS/OSS		11
ovary OSC		5
ovary OSS		4
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		20
Schneider line 2 Sg4		16
embryonic 1182-4H		7
embryonic GM2		8
embryonic Kc167		12
embryonic S1		16
embryonic S3		6
leg disc CME L1		9
wing disc CME-W2		6
wing disc ML-DmD8		10
wing disc ML-DmD9		8
wing disc ML-DmD16-c3		12
wing disc ML-DmD21		13
wing disc ML-DmD32		10
haltere disc ML-DmD17-c3		10
eye-antennal disc ML-DmD11		11
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		12
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		14
tumorous blood cells mbn2		6
ovary fGS/OSS		11
ovary OSC		5
ovary OSS		4
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		20
Schneider line 2 Sg4		16
embryonic 1182-4H		7
embryonic GM2		8
embryonic Kc167		12
embryonic S1		16
embryonic S3		6
leg disc CME L1		9
wing disc CME-W2		6
wing disc ML-DmD8		10
wing disc ML-DmD9		8
wing disc ML-DmD16-c3		12
wing disc ML-DmD21		13
wing disc ML-DmD32		10
haltere disc ML-DmD17-c3		10
eye-antennal disc ML-DmD11		11
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		12
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		14
tumorous blood cells mbn2		6
ovary fGS/OSS		11
ovary OSC		5
ovary OSS		4
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		20
Schneider line 2 Sg4		16
embryonic 1182-4H		7
embryonic GM2		8
embryonic Kc167		12
embryonic S1		16
embryonic S3		6
leg disc CME L1		9
wing disc CME-W2		6
wing disc ML-DmD8		10
wing disc ML-DmD9		8
wing disc ML-DmD16-c3		12
wing disc ML-DmD21		13
wing disc ML-DmD32		10
haltere disc ML-DmD17-c3		10
eye-antennal disc ML-DmD11		11
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		12
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		14
tumorous blood cells mbn2		6
ovary fGS/OSS		11
ovary OSC		5
ovary OSS		4
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		20
Schneider line 2 Sg4		16
embryonic 1182-4H		7
embryonic GM2		8
embryonic Kc167		12
embryonic S1		16
embryonic S3		6
leg disc CME L1		9
wing disc CME-W2		6
wing disc ML-DmD8		10
wing disc ML-DmD9		8
wing disc ML-DmD16-c3		12
wing disc ML-DmD21		13
wing disc ML-DmD32		10
haltere disc ML-DmD17-c3		10
eye-antennal disc ML-DmD11		11
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		12
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		14
tumorous blood cells mbn2		6
ovary fGS/OSS		11
ovary OSC		5
ovary OSS		4
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		20
Schneider line 2 Sg4		16
embryonic 1182-4H		7
embryonic GM2		8
embryonic Kc167		12
embryonic S1		16
embryonic S3		6
leg disc CME L1		9
wing disc CME-W2		6
wing disc ML-DmD8		10
wing disc ML-DmD9		8
wing disc ML-DmD16-c3		12
wing disc ML-DmD21		13
wing disc ML-DmD32		10
haltere disc ML-DmD17-c3		10
eye-antennal disc ML-DmD11		11
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		12
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		14
tumorous blood cells mbn2		6
ovary fGS/OSS		11
ovary OSC		5
ovary OSS		4
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		20
Schneider line 2 Sg4		16
embryonic 1182-4H		7
embryonic GM2		8
embryonic Kc167		12
embryonic S1		16
embryonic S3		6
leg disc CME L1		9
wing disc CME-W2		6
wing disc ML-DmD8		10
wing disc ML-DmD9		8
wing disc ML-DmD16-c3		12
wing disc ML-DmD21		13
wing disc ML-DmD32		10
haltere disc ML-DmD17-c3		10
eye-antennal disc ML-DmD11		11
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		12
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		14
tumorous blood cells mbn2		6
ovary fGS/OSS		11
ovary OSC		5
ovary OSS		4
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		20
Schneider line 2 Sg4		16
embryonic 1182-4H		7
embryonic GM2		8
embryonic Kc167		12
embryonic S1		16
embryonic S3		6
leg disc CME L1		9
wing disc CME-W2		6
wing disc ML-DmD8		10
wing disc ML-DmD9		8
wing disc ML-DmD16-c3		12
wing disc ML-DmD21		13
wing disc ML-DmD32		10
haltere disc ML-DmD17-c3		10
eye-antennal disc ML-DmD11		11
antennal disc ML-DmD20-c5		16
mixed discs ML-DmD4-c1		12
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		14
tumorous blood cells mbn2		6
ovary fGS/OSS		11
ovary OSC		5
ovary OSS		4
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		6
cold shock, 4-day adult		2
heat shock, 4-day adult		7
Cadmium 50 mM 6 hrs, larvae L3		7
Cadmium 50 mM 12 hrs, larvae L3		7
Cadmium 50 mM 48 hrs, 4-day adult		5
Cadmium 100 mM 48 hrs, 4-day adult		8
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		13
Ethanol 5% 3 hrs, larvae L3		5
Ethanol 10% 3 hrs, larvae L3		5
Caffeine 1.5 mg/ml 4 hrs, larvae L3		4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		9
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		11
Rotenone 2 μg 12 hrs, larvae L3		6
Rotenone 8 μg 12 hrs, larvae L3		4
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		6
cold shock, 4-day adult		2
heat shock, 4-day adult		7
Cadmium 50 mM 6 hrs, larvae L3		7
Cadmium 50 mM 12 hrs, larvae L3		7
Cadmium 50 mM 48 hrs, 4-day adult		5
Cadmium 100 mM 48 hrs, 4-day adult		8
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		13
Ethanol 5% 3 hrs, larvae L3		5
Ethanol 10% 3 hrs, larvae L3		5
Caffeine 1.5 mg/ml 4 hrs, larvae L3		4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		9
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		11
Rotenone 2 μg 12 hrs, larvae L3		6
Rotenone 8 μg 12 hrs, larvae L3		4
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		6
cold shock, 4-day adult		2
heat shock, 4-day adult		7
Cadmium 50 mM 6 hrs, larvae L3		7
Cadmium 50 mM 12 hrs, larvae L3		7
Cadmium 50 mM 48 hrs, 4-day adult		5
Cadmium 100 mM 48 hrs, 4-day adult		8
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		13
Ethanol 5% 3 hrs, larvae L3		5
Ethanol 10% 3 hrs, larvae L3		5
Caffeine 1.5 mg/ml 4 hrs, larvae L3		4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		9
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		11
Rotenone 2 μg 12 hrs, larvae L3		6
Rotenone 8 μg 12 hrs, larvae L3		4
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		6
cold shock, 4-day adult		2
heat shock, 4-day adult		7
Cadmium 50 mM 6 hrs, larvae L3		7
Cadmium 50 mM 12 hrs, larvae L3		7
Cadmium 50 mM 48 hrs, 4-day adult		5
Cadmium 100 mM 48 hrs, 4-day adult		8
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		13
Ethanol 5% 3 hrs, larvae L3		5
Ethanol 10% 3 hrs, larvae L3		5
Caffeine 1.5 mg/ml 4 hrs, larvae L3		4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		9
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		11
Rotenone 2 μg 12 hrs, larvae L3		6
Rotenone 8 μg 12 hrs, larvae L3		4
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		6
cold shock, 4-day adult		2
heat shock, 4-day adult		7
Cadmium 50 mM 6 hrs, larvae L3		7
Cadmium 50 mM 12 hrs, larvae L3		7
Cadmium 50 mM 48 hrs, 4-day adult		5
Cadmium 100 mM 48 hrs, 4-day adult		8
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		13
Ethanol 5% 3 hrs, larvae L3		5
Ethanol 10% 3 hrs, larvae L3		5
Caffeine 1.5 mg/ml 4 hrs, larvae L3		4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		9
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		11
Rotenone 2 μg 12 hrs, larvae L3		6
Rotenone 8 μg 12 hrs, larvae L3		4
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		6
cold shock, 4-day adult		2
heat shock, 4-day adult		7
Cadmium 50 mM 6 hrs, larvae L3		7
Cadmium 50 mM 12 hrs, larvae L3		7
Cadmium 50 mM 48 hrs, 4-day adult		5
Cadmium 100 mM 48 hrs, 4-day adult		8
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		13
Ethanol 5% 3 hrs, larvae L3		5
Ethanol 10% 3 hrs, larvae L3		5
Caffeine 1.5 mg/ml 4 hrs, larvae L3		4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		9
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		11
Rotenone 2 μg 12 hrs, larvae L3		6
Rotenone 8 μg 12 hrs, larvae L3		4
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		6
cold shock, 4-day adult		2
heat shock, 4-day adult		7
Cadmium 50 mM 6 hrs, larvae L3		7
Cadmium 50 mM 12 hrs, larvae L3		7
Cadmium 50 mM 48 hrs, 4-day adult		5
Cadmium 100 mM 48 hrs, 4-day adult		8
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		13
Ethanol 5% 3 hrs, larvae L3		5
Ethanol 10% 3 hrs, larvae L3		5
Caffeine 1.5 mg/ml 4 hrs, larvae L3		4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		9
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		11
Rotenone 2 μg 12 hrs, larvae L3		6
Rotenone 8 μg 12 hrs, larvae L3		4
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		6
cold shock, 4-day adult		2
heat shock, 4-day adult		7
Cadmium 50 mM 6 hrs, larvae L3		7
Cadmium 50 mM 12 hrs, larvae L3		7
Cadmium 50 mM 48 hrs, 4-day adult		5
Cadmium 100 mM 48 hrs, 4-day adult		8
Copper 0.5 mM 12 hrs, larvae L3		4
Copper 15 mM 48 hrs, 4-day adult		2
Zinc 5 mM 12 hrs, larvae L3		0
Zinc 4.5 mM 48 hrs, 4-day adult		2
Ethanol 2.5% 3 hrs, larvae L3		13
Ethanol 5% 3 hrs, larvae L3		5
Ethanol 10% 3 hrs, larvae L3		5
Caffeine 1.5 mg/ml 4 hrs, larvae L3		4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		9
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		9
Paraquat 10 mM 48 hrs, 4-day adult		11
Rotenone 2 μg 12 hrs, larvae L3		6
Rotenone 8 μg 12 hrs, larvae L3		4
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

GH03377

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0027597

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG17712-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable

CG17712^f05481

viable, with Scer\GAL4^pnr-MD237

CG17712^GD9448

Sterility

Allele

fertile

CG17712^f05481

Other Phenotypes

Allele

visible, with Scer\GAL4^pnr-MD237

CG17712^GD9448

Phenotype manifest in

Allele

trichogen cell, with Scer\GAL4^pnr-MD237

CG17712^GD9448

Classical Alleles ( 3 )

For All Classical Alleles Show

Allele of CG17712	Mutagen	Stocks	Known lesion
CG17712^f05481	piggyBac transposase	2	--
CG17712^G18185	P-element activity	1	--
CG17712^MI03455		1	--

Alleles Carried on Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG17712	Mutagen	Stocks	Known lesion
CG17712^GD9448	in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
CG17712^KK101419	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG17712^NIG.17712R	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Disrupted in

Df(2L)Exel7007

(Ryder, 2004.4.26)

Df(2L)Exel8005

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD9448}

P{KK101419}

P{NIG.17712R}

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

Mi{MIC}CG17712^MI03455

PBac{WH}CG17712^f05481

insertion of mobile activating element

P{EP}CG17712^G18185

Gene Ontology: Function, Process & Cellular Component ( 1 unique term )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 1 term )

Molecular Function

CV term

Evidence

References

oxidoreductase activity

inferred from electronic annotation with InterPro:IPR000683

(FlyBase Curators et al., 2004-)

Biological Process ( 0 terms)

Cellular Component ( 0 terms)

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG17712 allele

Gene

References

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

59594

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0027597

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

33356

Orthologs

OrthoDB Orthologs (43) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG6PZJSJ

Dipteran inclusive ortholog search

EOG6Z0BF8

Insect inclusive ortholog search

EOG62BW52

Arthropod inclusive ortholog search

EOG62FR00

Metazoa inclusive ortholog search

EOG6KDKDS

Orthologs in Drosophila Species (EOG6PZJSJ)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA14620

Drosophila persimilis

Dper\GL18471

Drosophila willistoni

Dwil\GK21156

Drosophila willistoni

Dwil\GK18466

Drosophila virilis

Dvir\GJ17446

Drosophila mojavensis

Dmoj\GI13770

Drosophila grimshawi

Dgri\GH25259

Drosophila grimshawi

Dgri\GH25023

Orthologs in non-Drosophila Dipterans (EOG6Z0BF8)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL005958

Anopheles gambiae

Malaria mosquito

Agam\AGAP008097

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ802380

Orthologs in non-Dipteran Insects (EOG62BW52)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\LOC724822

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG005062

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH22803

Atta cephalotes

Leafcutter ant

Acep\ACEP17821

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO20584

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL21440

Linepithema humile

Argentine ant

Lhum\LH14128

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB12473

Solenopsis invicta

Red fire ant

Sinv\SINV21428

Acyrthosiphon pisum

Pea aphid

Apim\ACYPI009593

Bombyx mori

Silkmoth

Bmor\BGIBMGA012121

Pediculus humanus

Human body louse

Phum\PHUM308680

Tribolium castaneum

Red flour beetle

Tcas\TC000117

Orthologs in non-Insect Arthropods (EOG62FR00)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Ixodes scapularis

Deer tick

Isca\ISCW009946

Orthologs in non-Arthropod Metazoa (EOG6KDKDS)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_020964gn

Danio rerio

Zebrafish

Drer\gfod2

Danio rerio

Zebrafish

Drer\si:ch211-276f18.2

Xenopus tropicalis

Western clawed frog

Xtro\gfod1

Xenopus tropicalis

Western clawed frog

Xtro\gfod2

Gallus gallus

Domestic chicken

Ggal\GFOD1

Gallus gallus

Domestic chicken

Ggal\GFOD2

Mus musculus

House mouse

Mmus\Gfod1

Rattus norvegicus

Norway rat

Rnor\Gfod2

Rattus norvegicus

Norway rat

Rnor\Gfod1

Homo sapiens

Human

Hsap\GFOD1

Homo sapiens

Human

Hsap\GFOD2

Human Orthologs (2)

Gene

OMIM

HGNC

Hsap\GFOD1

Hsap\GFOD2

AAA Orthologs (11) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA14620

Drosophila persimilis

Dper\GL18471

Drosophila willistoni

Dwil\GK18466

Drosophila virilis

Dvir\GJ17446

Drosophila mojavensis

Dmoj\GI13770

Drosophila grimshawi

Dgri\GH25023

Stocks & Reagents

Stocks Listed in FlyBase ( 7 )

Bloomington

18871

w¹¹¹⁸; PBac{WH}CG17712^f05481

27437

y¹ w^*; P{EP}CG17712^G18185

37194

y¹ w^*; Mi{MIC}CG17712^MI03455

Harvard

PBac{WH}CG17712^f05481

VDRC

v105119

P{KK101419}VIE-260B

v32985

w¹¹¹⁸; P{GD9448}v32985

v32987

w¹¹¹⁸; P{GD9448}v32987

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 18 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

GH03377

Other clones

DPiM_GH03377

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

FGH104G03

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0027597

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

33356

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_134775

RefSeq (Proteins)

•

NP_608619

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

33356

UniProtKB/TrEMBL

•

Q9Y153

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Oxidoreductase, N-terminal (IPR000683)

NAD(P)-binding domain (IPR016040)

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

•

GH03377

Linkouts

BioGRID - A database of protein and genetic interactions

•

59594

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0027597

DRSC - Results from RNAi screens.

•

FBgn0027597

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0027597

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG17712-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0027597

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

33356

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

33356

modMine - Data generated by the modENCODE project.

•

FBgn0027597

Synonyms & Secondary IDs ( 2 )

Reported As

Symbol Synonym

BcDNA:GH03377

(Giot et al., 2003, )

CG17712

(Keleman et al., 2009.8.5, Japanese National Institute of Genetics, 2012.5.21)

Name Synonym

Secondary FlyBase IDs

References ( 15 )

Supplementary material

Graveley et al., 2011, Nature 471(7339):: Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980]
The modENCODE Consortium, 2010, Science 330(6012):: DataS14: Gene co-expression clusters. [FBrf0213979]
Mummery-Widmer et al., 2009, Nature 458(7241):: Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Giot et al., 2003, Science 302(5651):: Tables S1 to S7. [FBrf0166452]

Personal communication to FlyBase

Bellen, 2011.11.10, set958.xml: set958.xml [FBrf0216694]
Bellen, 2009.5.5, BDGP_2009_0507.GenExel.xml: BDGP_2009_0507.GenExel.xml [FBrf0207859]
Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510]
Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase.: Exelixis insertion alleles that are not in FlyBase. [FBrf0179797]
FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.: Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
Ryder, 2004.4.26, Exelixis CG deletion data.: Exelixis CG deletion data. [FBrf0184335]
BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file): Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]

Stock list

Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY.: RNAi stocks available from NIG-FLY. [FBrf0218457]

Website

Fisher et al., 2012, BDGP insitu homepage: BDGP insitu homepage [FBrf0219073]