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Gene Dmel\CG8611

General Information
Symbol	Dmel\CG8611	Species	D. melanogaster
Name		Annotation symbol	CG8611
Feature type	protein_coding_gene	FlyBase ID	FBgn0027602
Gene Model Status	Current	Stock availability	2 publicly available
Also Known As	BcDNA:GH02833
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	16A5-16A5	Sequence location	X:17,307,300..17,316,178 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG8611 (FBgn0027602). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ATP-dependent RNA helicase activity. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: DNA/RNA helicase, DEAD/DEAH box type, N-terminal; Domain of unknown function DUF4217; Helicase, C-terminal; Helicase, superfamily 1/2, ATP-binding domain; RNA helicase, ATP-dependent, DEAD-box, conserved site; RNA helicase, DEAD-box type, Q motif. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages, during early larval stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1627032_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG8611. Gene sequence location is X:17307830..17316188.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03	Polypeptides CG8611-PC Transcripts CG8611-RC
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 16A5-16A5   Limits computationally determined from genome sequence between P{EP}bazEP1446 and P{EP}EP1464
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG8611 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.51
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG8611-RA FBtr0074439  NM_132986   3614   974 CG8611-RB FBtr0074440  NM_176749   4145   975 CG8611-RC FBtr0340619     3917   828
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG8611-PA   FBpp0074213   107.8   974   10.17     NP_573214   AAF48727 CG8611-PB   FBpp0074214   108.0   975   10.17     NP_788922   AAO41693 CG8611-PC   FBpp0309483   91.8   828   9.54
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • RNA helicase, ATP-dependent, DEAD-box, conserved site (IPR000629) Helicase, C-terminal (IPR001650) DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545) Domain of unknown function DUF4217 (IPR025313) RNA helicase, DEAD-box type, Q motif (IPR014014) Helicase, superfamily 1/2, ATP-binding domain (IPR014001) P-loop containing nucleoside triphosphate hydrolase (IPR027417)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201485   AA264390   AA541187   AE014298 AAF48727   AE014298 AAO41693   AF145609 AAD38584   AI063259   AI401880   AI514990   AI532324   AI541879   AI542812   BI213945   BI215125   BI243126   BI353792   BI355272   BI356731   BI357247   BI366721   BI579575   BI633436   BI635742   BI641625   BT125988   CO177848   CO282713   CO295946   CO296921   CO305647   CO320332   CO339440   EC052049   EC052572   EC054554   EC055094   EC056628   EC064242   EC075776   EC085058   EC237907   EC239202   EC254313   GH941847   GH943186   GH946291   GH946488   GH946760   GH947079   GH947674   GH950627   GH951523   GH962963   GH963332   GH963432   GH964147   GH964216   GH964427   GH964886   GH965359   GH967129   GH967863   GH968455   GH969520   GH972541   GH975060   GH977367   GH978811   GH978944   GH979272   GH980726   GH981709   GH982013   GH982357   GH983908
UniProtKB/Swiss-Prot	Q86B47
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism | ubiquitous   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | faint & ubiquitous   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   head mesoderm   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) visceral muscle primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   dorsal pharyngeal muscle   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) embryonic/larval visceral muscle   (Fisher et al., 2012) organism | faint & ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 5 of adulthood & male -- day 7 of adulthood & male   spermatozoon   (Dorus et al., 2006)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    82.25 Larval Midgut    25.9 Larval Hindgut    32.9 Larval Malpighian Tubules    12.6 Larval Fat Body    15.2 Larval Salivary Gland    58.7 Larval Trachea    43.925 Larval Carcass    64.325 Adult Head    21.9 Adult Eye    14.85 Adult Brain    28.8 Adult Thoracic-Abdominal Ganglion    38.7 Adult Crop    23.5 Adult Midgut    28.5 Adult Hindgut    21 Adult Malpighian Tubules    21.8 Adult Fat Body    39 Adult Salivary Gland    39.4 Adult Heart    19.375 Adult VirginFemale Spermatheca    35.1 Adult InseminatedFemale Spermatheca    56.8 Adult Ovary    126 Adult Testis    5.1 Adult Male Accessory Gland    63.1 Adult Carcass    25.6 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    82.25 Larval Midgut    25.9 Larval Hindgut    32.9 Larval Malpighian Tubules    12.6 Larval Fat Body    15.2 Larval Salivary Gland    58.7 Larval Trachea    43.925 Larval Carcass    64.325 Adult Head    21.9 Adult Eye    14.85 Adult Brain    28.8 Adult Thoracic-Abdominal Ganglion    38.7 Adult Crop    23.5 Adult Midgut    28.5 Adult Hindgut    21 Adult Malpighian Tubules    21.8 Adult Fat Body    39 Adult Salivary Gland    39.4 Adult Heart    19.375 Adult VirginFemale Spermatheca    35.1 Adult InseminatedFemale Spermatheca    56.8 Adult Ovary    126 Adult Testis    5.1 Adult Male Accessory Gland    63.1 Adult Carcass    25.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    82.25 Larval Midgut    25.9 Larval Hindgut    32.9 Larval Malpighian Tubules    12.6 Larval Fat Body    15.2 Larval Salivary Gland    58.7 Larval Trachea    43.925 Larval Carcass    64.325 Adult Head    21.9 Adult Eye    14.85 Adult Brain    28.8 Adult Thoracic-Abdominal Ganglion    38.7 Adult Crop    23.5 Adult Midgut    28.5 Adult Hindgut    21 Adult Malpighian Tubules    21.8 Adult Fat Body    39 Adult Salivary Gland    39.4 Adult Heart    19.375 Adult VirginFemale Spermatheca    35.1 Adult InseminatedFemale Spermatheca    56.8 Adult Ovary    126 Adult Testis    5.1 Adult Male Accessory Gland    63.1 Adult Carcass    25.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    82.25 Larval Midgut    25.9 Larval Hindgut    32.9 Larval Malpighian Tubules    12.6 Larval Fat Body    15.2 Larval Salivary Gland    58.7 Larval Trachea    43.925 Larval Carcass    64.325 Adult Head    21.9 Adult Eye    14.85 Adult Brain    28.8 Adult Thoracic-Abdominal Ganglion    38.7 Adult Crop    23.5 Adult Midgut    28.5 Adult Hindgut    21 Adult Malpighian Tubules    21.8 Adult Fat Body    39 Adult Salivary Gland    39.4 Adult Heart    19.375 Adult VirginFemale Spermatheca    35.1 Adult InseminatedFemale Spermatheca    56.8 Adult Ovary    126 Adult Testis    5.1 Adult Male Accessory Gland    63.1 Adult Carcass    25.6 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    82.25 Larval Midgut    25.9 Larval Hindgut    32.9 Larval Malpighian Tubules    12.6 Larval Fat Body    15.2 Larval Salivary Gland    58.7 Larval Trachea    43.925 Larval Carcass    64.325 Adult Head    21.9 Adult Eye    14.85 Adult Brain    28.8 Adult Thoracic-Abdominal Ganglion    38.7 Adult Crop    23.5 Adult Midgut    28.5 Adult Hindgut    21 Adult Malpighian Tubules    21.8 Adult Fat Body    39 Adult Salivary Gland    39.4 Adult Heart    19.375 Adult VirginFemale Spermatheca    35.1 Adult InseminatedFemale Spermatheca    56.8 Adult Ovary    126 Adult Testis    5.1 Adult Male Accessory Gland    63.1 Adult Carcass    25.6 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    82.25 Larval Midgut    25.9 Larval Hindgut    32.9 Larval Malpighian Tubules    12.6 Larval Fat Body    15.2 Larval Salivary Gland    58.7 Larval Trachea    43.925 Larval Carcass    64.325 Adult Head    21.9 Adult Eye    14.85 Adult Brain    28.8 Adult Thoracic-Abdominal Ganglion    38.7 Adult Crop    23.5 Adult Midgut    28.5 Adult Hindgut    21 Adult Malpighian Tubules    21.8 Adult Fat Body    39 Adult Salivary Gland    39.4 Adult Heart    19.375 Adult VirginFemale Spermatheca    35.1 Adult InseminatedFemale Spermatheca    56.8 Adult Ovary    126 Adult Testis    5.1 Adult Male Accessory Gland    63.1 Adult Carcass    25.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    82.25 Larval Midgut    25.9 Larval Hindgut    32.9 Larval Malpighian Tubules    12.6 Larval Fat Body    15.2 Larval Salivary Gland    58.7 Larval Trachea    43.925 Larval Carcass    64.325 Adult Head    21.9 Adult Eye    14.85 Adult Brain    28.8 Adult Thoracic-Abdominal Ganglion    38.7 Adult Crop    23.5 Adult Midgut    28.5 Adult Hindgut    21 Adult Malpighian Tubules    21.8 Adult Fat Body    39 Adult Salivary Gland    39.4 Adult Heart    19.375 Adult VirginFemale Spermatheca    35.1 Adult InseminatedFemale Spermatheca    56.8 Adult Ovary    126 Adult Testis    5.1 Adult Male Accessory Gland    63.1 Adult Carcass    25.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    82.25 Larval Midgut    25.9 Larval Hindgut    32.9 Larval Malpighian Tubules    12.6 Larval Fat Body    15.2 Larval Salivary Gland    58.7 Larval Trachea    43.925 Larval Carcass    64.325 Adult Head    21.9 Adult Eye    14.85 Adult Brain    28.8 Adult Thoracic-Abdominal Ganglion    38.7 Adult Crop    23.5 Adult Midgut    28.5 Adult Hindgut    21 Adult Malpighian Tubules    21.8 Adult Fat Body    39 Adult Salivary Gland    39.4 Adult Heart    19.375 Adult VirginFemale Spermatheca    35.1 Adult InseminatedFemale Spermatheca    56.8 Adult Ovary    126 Adult Testis    5.1 Adult Male Accessory Gland    63.1 Adult Carcass    25.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    21.9   NA  Eye    14.85   NA  Brain    28.8   82.25  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    38.7   NA  Crop    23.5   25.9  Midgut    28.5   32.9  Hindgut    21   12.6  Malpighian Tubules    no informative data   no informative data  Fat Body    39   58.7  Salivary Gland    no informative data   NA  Heart    19.375   43.925  Trachea    NA   NA  VirginFemale Spermatheca    35.1   NA  InseminatedFemale Spermatheca    56.8   NA  Ovary    126   NA  Testis    5.1   NA  Male Accessory Gland    63.1   64.325  Carcass    25.6 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    8 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    3 head, mated 20-day female    2 head, mated 1-day male    1 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    3 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    3 carcass, 20-day adult    2 ovary, virgin 4-day female    17 ovary, mated 4-day female    18 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    8 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    3 head, mated 20-day female    2 head, mated 1-day male    1 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    3 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    3 carcass, 20-day adult    2 ovary, virgin 4-day female    17 ovary, mated 4-day female    18 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    8 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    3 head, mated 20-day female    2 head, mated 1-day male    1 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    3 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    3 carcass, 20-day adult    2 ovary, virgin 4-day female    17 ovary, mated 4-day female    18 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    8 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    3 head, mated 20-day female    2 head, mated 1-day male    1 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    3 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    3 carcass, 20-day adult    2 ovary, virgin 4-day female    17 ovary, mated 4-day female    18 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    8 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    3 head, mated 20-day female    2 head, mated 1-day male    1 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    3 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    3 carcass, 20-day adult    2 ovary, virgin 4-day female    17 ovary, mated 4-day female    18 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    8 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    3 head, mated 20-day female    2 head, mated 1-day male    1 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    3 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    3 carcass, 20-day adult    2 ovary, virgin 4-day female    17 ovary, mated 4-day female    18 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    8 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    3 head, mated 20-day female    2 head, mated 1-day male    1 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    3 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    3 carcass, 20-day adult    2 ovary, virgin 4-day female    17 ovary, mated 4-day female    18 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    6 central nervous system, larvae L3    8 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    1 head, virgin 20-day female    2 head, mated 1-day female    2 head, mated 4-day female    3 head, mated 20-day female    2 head, mated 1-day male    1 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    1 digestive system, 4-day adult    3 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    1 fat body, pupae P8    0 carcass, larvae L3 wandering    6 carcass, 1-day adult    1 carcass, 4-day adult    3 carcass, 20-day adult    2 ovary, virgin 4-day female    17 ovary, mated 4-day female    18 testis, mated 4-day male    1 accessory gland, mated 4-day male    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-12 hour embryonic stages, during early larval stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    30 embryo 04-06hr    31 embryo 06-08hr    32 embryo 08-10hr    28 embryo 10-12hr    25 embryo 12-14hr    15 embryo 14-16hr    14 embryo 16-18hr    10 embryo 18-20hr    7 embryo 20-22hr    15 embryo 22-24hr    12 larva L1    19 larva L2    9 larva L3 12hr old    6 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    6 white prepupae 24hr    5 pupae 2d postWPP    4 pupae 3d postWPP    2 pupae 4d postWPP    3 adult male 01day    2 adult male 05day    1 adult male 30day    2 adult female 01day    14 adult female 05day    20 adult female 30day    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (29) embryo 02-04hr  (30) embryo 04-06hr  (31) embryo 06-08hr  (32) embryo 08-10hr  (28) embryo 10-12hr    25 embryo 12-14hr    15 embryo 14-16hr    14 embryo 16-18hr    10 embryo 18-20hr    7 embryo 20-22hr    15 embryo 22-24hr    12 larva L1    19 larva L2    9 larva L3 12hr old    6 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    6 white prepupae 24hr    5 pupae 2d postWPP    4 pupae 3d postWPP    2 pupae 4d postWPP    3 adult male 01day    2 adult male 05day    1 adult male 30day    2 adult female 01day    14 adult female 05day    20 adult female 30day    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    30 embryo 04-06hr    31 embryo 06-08hr    32 embryo 08-10hr    28 embryo 10-12hr    25 embryo 12-14hr    15 embryo 14-16hr    14 embryo 16-18hr    10 embryo 18-20hr    7 embryo 20-22hr    15 embryo 22-24hr    12 larva L1    19 larva L2    9 larva L3 12hr old    6 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    6 white prepupae 24hr    5 pupae 2d postWPP    4 pupae 3d postWPP    2 pupae 4d postWPP    3 adult male 01day    2 adult male 05day    1 adult male 30day    2 adult female 01day    14 adult female 05day    20 adult female 30day    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    30 embryo 04-06hr    31 embryo 06-08hr    32 embryo 08-10hr    28 embryo 10-12hr    25 embryo 12-14hr    15 embryo 14-16hr    14 embryo 16-18hr    10 embryo 18-20hr    7 embryo 20-22hr    15 embryo 22-24hr    12 larva L1    19 larva L2    9 larva L3 12hr old    6 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    6 white prepupae 24hr    5 pupae 2d postWPP    4 pupae 3d postWPP    2 pupae 4d postWPP    3 adult male 01day    2 adult male 05day    1 adult male 30day    2 adult female 01day    14 adult female 05day    20 adult female 30day    20 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    30 embryo 04-06hr    31 embryo 06-08hr    32 embryo 08-10hr    28 embryo 10-12hr    25 embryo 12-14hr    15 embryo 14-16hr    14 embryo 16-18hr    10 embryo 18-20hr    7 embryo 20-22hr    15 embryo 22-24hr    12 larva L1    19 larva L2    9 larva L3 12hr old    6 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    6 white prepupae 24hr    5 pupae 2d postWPP    4 pupae 3d postWPP    2 pupae 4d postWPP    3 adult male 01day    2 adult male 05day    1 adult male 30day    2 adult female 01day    14 adult female 05day    20 adult female 30day    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  29 embryo 02-04hr  30 embryo 04-06hr  31 embryo 06-08hr  32 embryo 08-10hr  28 embryo 10-12hr    25 embryo 12-14hr    15 embryo 14-16hr    14 embryo 16-18hr    10 embryo 18-20hr    7 embryo 20-22hr    15 embryo 22-24hr    12 larva L1    19 larva L2    9 larva L3 12hr old    6 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    6 white prepupae 24hr    5 pupae 2d postWPP    4 pupae 3d postWPP    2 pupae 4d postWPP    3 adult male 01day    2 adult male 05day    1 adult male 30day    2 adult female 01day    14 adult female 05day    20 adult female 30day    20 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    30 embryo 04-06hr    31 embryo 06-08hr    32 embryo 08-10hr    28 embryo 10-12hr    25 embryo 12-14hr    15 embryo 14-16hr    14 embryo 16-18hr    10 embryo 18-20hr    7 embryo 20-22hr    15 embryo 22-24hr    12 larva L1    19 larva L2    9 larva L3 12hr old    6 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    6 white prepupae 24hr    5 pupae 2d postWPP    4 pupae 3d postWPP    2 pupae 4d postWPP    3 adult male 01day    2 adult male 05day    1 adult male 30day    2 adult female 01day    14 adult female 05day    20 adult female 30day    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    29 embryo 02-04hr    30 embryo 04-06hr    31 embryo 06-08hr    32 embryo 08-10hr    28 embryo 10-12hr    25 embryo 12-14hr    15 embryo 14-16hr    14 embryo 16-18hr    10 embryo 18-20hr    7 embryo 20-22hr    15 embryo 22-24hr    12 larva L1    19 larva L2    9 larva L3 12hr old    6 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    4 larva L3 puffstage 7-9    5 white prepupae new    4 white prepupae 12hr    6 white prepupae 24hr    5 pupae 2d postWPP    4 pupae 3d postWPP    2 pupae 4d postWPP    3 adult male 01day    2 adult male 05day    1 adult male 30day    2 adult female 01day    14 adult female 05day    20 adult female 30day    20 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    14 Schneider line 2 Sg4    15 embryonic 1182-4H    8 embryonic GM2    7 embryonic Kc167    8 embryonic S1    7 embryonic S3    11 leg disc CME L1    13 wing disc CME-W2    9 wing disc ML-DmD8    8 wing disc ML-DmD9    8 wing disc ML-DmD16-c3    12 wing disc ML-DmD21    14 wing disc ML-DmD32    11 haltere disc ML-DmD17-c3    9 eye-antennal disc ML-DmD11    13 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    13 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    5 ovary fGS/OSS    9 ovary OSC    9 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    14 Schneider line 2 Sg4    15 embryonic 1182-4H    8 embryonic GM2    7 embryonic Kc167    8 embryonic S1    7 embryonic S3    11 leg disc CME L1    13 wing disc CME-W2    9 wing disc ML-DmD8    8 wing disc ML-DmD9    8 wing disc ML-DmD16-c3    12 wing disc ML-DmD21    14 wing disc ML-DmD32    11 haltere disc ML-DmD17-c3    9 eye-antennal disc ML-DmD11    13 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    13 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    5 ovary fGS/OSS    9 ovary OSC    9 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    14 Schneider line 2 Sg4    15 embryonic 1182-4H    8 embryonic GM2    7 embryonic Kc167    8 embryonic S1    7 embryonic S3    11 leg disc CME L1    13 wing disc CME-W2    9 wing disc ML-DmD8    8 wing disc ML-DmD9    8 wing disc ML-DmD16-c3    12 wing disc ML-DmD21    14 wing disc ML-DmD32    11 haltere disc ML-DmD17-c3    9 eye-antennal disc ML-DmD11    13 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    13 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    5 ovary fGS/OSS    9 ovary OSC    9 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    14 Schneider line 2 Sg4    15 embryonic 1182-4H    8 embryonic GM2    7 embryonic Kc167    8 embryonic S1    7 embryonic S3    11 leg disc CME L1    13 wing disc CME-W2    9 wing disc ML-DmD8    8 wing disc ML-DmD9    8 wing disc ML-DmD16-c3    12 wing disc ML-DmD21    14 wing disc ML-DmD32    11 haltere disc ML-DmD17-c3    9 eye-antennal disc ML-DmD11    13 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    13 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    5 ovary fGS/OSS    9 ovary OSC    9 ovary OSS    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    14 Schneider line 2 Sg4    15 embryonic 1182-4H    8 embryonic GM2    7 embryonic Kc167    8 embryonic S1    7 embryonic S3    11 leg disc CME L1    13 wing disc CME-W2    9 wing disc ML-DmD8    8 wing disc ML-DmD9    8 wing disc ML-DmD16-c3    12 wing disc ML-DmD21    14 wing disc ML-DmD32    11 haltere disc ML-DmD17-c3    9 eye-antennal disc ML-DmD11    13 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    13 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    5 ovary fGS/OSS    9 ovary OSC    9 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    14 Schneider line 2 Sg4    15 embryonic 1182-4H    8 embryonic GM2    7 embryonic Kc167    8 embryonic S1    7 embryonic S3    11 leg disc CME L1    13 wing disc CME-W2    9 wing disc ML-DmD8    8 wing disc ML-DmD9    8 wing disc ML-DmD16-c3    12 wing disc ML-DmD21    14 wing disc ML-DmD32    11 haltere disc ML-DmD17-c3    9 eye-antennal disc ML-DmD11    13 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    13 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    5 ovary fGS/OSS    9 ovary OSC    9 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    14 Schneider line 2 Sg4    15 embryonic 1182-4H    8 embryonic GM2    7 embryonic Kc167    8 embryonic S1    7 embryonic S3    11 leg disc CME L1    13 wing disc CME-W2    9 wing disc ML-DmD8    8 wing disc ML-DmD9    8 wing disc ML-DmD16-c3    12 wing disc ML-DmD21    14 wing disc ML-DmD32    11 haltere disc ML-DmD17-c3    9 eye-antennal disc ML-DmD11    13 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    13 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    5 ovary fGS/OSS    9 ovary OSC    9 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    14 Schneider line 2 Sg4    15 embryonic 1182-4H    8 embryonic GM2    7 embryonic Kc167    8 embryonic S1    7 embryonic S3    11 leg disc CME L1    13 wing disc CME-W2    9 wing disc ML-DmD8    8 wing disc ML-DmD9    8 wing disc ML-DmD16-c3    12 wing disc ML-DmD21    14 wing disc ML-DmD32    11 haltere disc ML-DmD17-c3    9 eye-antennal disc ML-DmD11    13 antennal disc ML-DmD20-c5    8 mixed discs ML-DmD4-c1    13 CNS ML-DmBG1-c1    13 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    5 ovary fGS/OSS    9 ovary OSC    9 ovary OSS    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    2 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    5 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    2 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    5 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    2 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    5 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    2 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    5 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    2 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    5 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    2 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    5 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    2 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    5 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    6 cold shock, 4-day adult    2 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    1 Cadmium 50 mM 48 hrs, 4-day adult    7 Cadmium 100 mM 48 hrs, 4-day adult    10 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    12 Ethanol 5% 3 hrs, larvae L3    1 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    1 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    9 Caffeine 25 mg/ml 48 hrs, 4-day adult    5 Paraquat 5 mM 48 hrs, 4-day adult    9 Paraquat 10 mM 48 hrs, 4-day adult    9 Rotenone 2 μg 12 hrs, larvae L3    2 Rotenone 8 μg 12 hrs, larvae L3    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_08 mE1_20_mRNA_expression_cluster_05
External Data & Images
Linkouts	BDGP expression data • GH02833 LD47310 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0027602 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8611-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG8611GD13987 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG8611 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG8611 Class Mutagen Stocks Known lesion CG8611GD13987 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG8611KK108067 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG8611NIG.8611R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD13987} NA P{KK108067} NA P{NIG.8611R} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
ATP binding inferred from electronic annotation with InterPro:IPR000629, InterPro:IPR001650, InterPro:IPR011545 (FlyBase Curators et al., 2004-) ATP-dependent RNA helicase activity inferred from sequence or structural similarity with EMBL:X98743 (FlyBase, 1992-) inferred from sequence or structural similarity with Saccharomyces DBP7 (Lasko, 2000) nucleic acid binding inferred from electronic annotation with InterPro:IPR000629, InterPro:IPR001650, InterPro:IPR011545 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
CG8611 - CG1785 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8611 - CG31111 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8611 - CG4415 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8611 - CG6652 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8611 - CG7137 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8611 - Ns2 experimental knowledge based (Guruharsha et al., 2011) CG8611 - Sbp2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8611 - grau anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) CG8611 - l(1)G0020 experimental knowledge based (Guruharsha et al., 2011)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG8611 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 59053 DroID - A comprehensive database of gene and protein interactions. • FBgn0027602 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32725
Orthologs
OrthoDB Orthologs (36) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6SJ607 Dipteran inclusive ortholog search EOG6B2T57 Insect inclusive ortholog search EOG6X6B4C Arthropod inclusive ortholog search EOG615DVF Metazoa inclusive ortholog search EOG6VHZ0D
Orthologs in Drosophila Species (EOG6SJ607)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG8611     Drosophila simulans   Dsim\GD17360 Y   Drosophila sechellia   Dsec\GM13317 Y   Drosophila erecta   Dere\GG18185 Y   Drosophila yakuba   Dyak\GE15594 Y   Drosophila ananassae   Dana\GF22616 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA27288 Y   Drosophila persimilis   Dper\GL19832 Y   Drosophila willistoni   Dwil\GK19923 Y   Drosophila virilis   Dvir\GJ19298 Y   Drosophila mojavensis   Dmoj\GI14650 Y   Drosophila grimshawi   Dgri\GH24071 Y
Orthologs in non-Drosophila Dipterans (EOG6B2T57)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL008463   Anopheles gambiae Malaria mosquito  Agam\AGAP010670   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ017338
Orthologs in non-Dipteran Insects (EOG6X6B4C)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB46847   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG019919   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH10094   Atta cephalotes Leafcutter ant  Acep\ACEP20630   Camponotus floridanus Florida carpenter ant  Cflo\CFLO22512   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL15891   Linepithema humile Argentine ant  Lhum\LH12630   Pogonomyrmex barbatus Red harvester ant  Pbar\PB19696   Solenopsis invicta Red fire ant  Sinv\SINV18040   Acyrthosiphon pisum Pea aphid  Apim\ACYPI006678   Pediculus humanus Human body louse  Phum\PHUM339240   Tribolium castaneum Red flour beetle  Tcas\TC016196
Orthologs in non-Insect Arthropods (EOG615DVF)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_309224
Orthologs in non-Arthropod Metazoa (EOG6VHZ0D)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_019320gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016671gn   Danio rerio Zebrafish  Drer\si:ch211-89p1.3   Xenopus tropicalis Western clawed frog  Xtro\ddx31   Gallus gallus Domestic chicken  Ggal\DDX31   Mus musculus House mouse  Mmus\Ddx31   Rattus norvegicus Norway rat  Rnor\Ddx31   Homo sapiens Human  Hsap\DDX31
Human Orthologs (1)
Gene OMIM HGNC Hsap\DDX31
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD17360 Drosophila sechellia Dsec\GM13317 Drosophila erecta Dere\GG18185 Drosophila yakuba Dyak\GE15594 Drosophila ananassae Dana\GF22616 Drosophila pseudoobscura pseudoobscura Dpse\GA27288 Drosophila persimilis Dper\GL19832 Drosophila willistoni Dwil\GK19923 Drosophila virilis Dvir\GJ19298 Drosophila mojavensis Dmoj\GI14650 Drosophila grimshawi Dgri\GH24071
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v104379 P{KK108067}VIE-260B v28936 w1118; P{GD13987}v28936
Genomic Clones ( 1 )
	BACR35G15 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 71 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH02833 LD47310
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM25150 GM30168 LD04391 LD08062 LD21022 LD46643 RE19596 RE40683 RE42932 RE43668 RE52318 RE73633 SD03792 SD07834 SD09279 SD17201 SD25069 SD27524
Other clones	45444 80194 81777 146238 179668 214379.31 EC052049 EC052572 EC054554 EC055094 EC056628 EK054502 EK161028 EK212347 EK215429 EK249151 EK284053 EP01964 RE21344 RP004165251 RP004172519 RP004204184 RP004205900 RP004213834 RP004216246 RP004219356 RP004222438 RP004222794 RP004225679 RP004229426 RP004238057 RP004252008 RP004253947 RP004254870 RP004257038 RP004262264 RP004293734 RP004351023 RP004397026 RP004440524 RP004454926 RP004462014 RP004472321 RP004492189 RP004498077 RP004504089 RP004506217 RP004506330 RP004514626 RP004515897 RP004519371
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0027602 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32725
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132986 NM_176749 RefSeq (Proteins) • NP_573214 NP_788922 DDBJ / EMBL / GenBank • AAD38584 AAF48727 AAO41693 AF145609 AI063259 AI401880 Entrez Gene - A searchable database of RefSeq genes. • 32725 UniProtKB/Swiss-Prot • Q86B47
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • RNA helicase, ATP-dependent, DEAD-box, conserved site (IPR000629) Helicase, C-terminal (IPR001650) DNA/RNA helicase, DEAD/DEAH box type, N-terminal (IPR011545) Domain of unknown function DUF4217 (IPR025313) RNA helicase, DEAD-box type, Q motif (IPR014014) Helicase, superfamily 1/2, ATP-binding domain (IPR014001) P-loop containing nucleoside triphosphate hydrolase (IPR027417) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GH02833 LD47310
Linkouts
	BioGRID - A database of protein and genetic interactions • 59053 DroID - A comprehensive database of gene and protein interactions. • FBgn0027602 DRSC - Results from RNAi screens. • FBgn0027602 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0027602 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8611-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0027602 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32725 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32725 modMine - Data generated by the modENCODE project. • FBgn0027602
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	BcDNA:GH02833 (Giot et al., 2003, Bowler et al., 2006) cg8611 (Lasko, 2000) CG8611 (Dorus et al., 2006, Keleman et al., 2009.8.5, Andersen et al., 2010, Japanese National Institute of Genetics, 2012.5.21) DmRH11 (Boudet et al., 2001)
Name Synonym
Secondary FlyBase IDs
References ( 22 )
Generate a list of	All references relating to this gene ( 22 )
List References by type	Research paper  ( 5 ) Supplementary material  ( 6 ) Personal communication to FlyBase  ( 5 ) FlyBase analysis  ( 1 ) Stock list  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...