Gene model reviewed during 5.44
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\morgue using the Feature Mapper tool.
Reverse-transcriptase PCR assays show that morgue is expressed throughout development. During embryonic development maximal expression is observed at 4-8 hr. After this time expression is low until third instar, beyond which it is expressed at high levels. Sexually dimorphic expression levels are observed with higher expression levels in male head and body versus female. During the period of apoptosis in the developing ommatidia, morgue is initially high in secondary and tertiary pigment cells after which it declines and is not detectable in the mature eye in these cells. In contrast, expression remains high in the primary pigment cells. Expression was not detected in cone or bristle cells at any stage of development.
GBrowse - Visual display of RNA-Seq signalsView Dmel\morgue in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Identification: in a screen for genes involved in retinal apoptosis.
morgue hypomorphs have extra lattice cells in the adult eye due to insufficient cell death during development.
Shows particularly robust cycling of transcription in adult heads, as assessed by expression analysis using high density oligonucleotide arrays with probe generated during three 12-point time course experiments over the course of 6 days. Shows significant change of expression pattern in circadian mutant background; decreased expression in per01, tim01 and ClkJrk background.