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Gene Dmel\blot

General Information
Symbol	Dmel\blot	Species	D. melanogaster
Name	bloated tubules	Annotation symbol	CG3897
Feature type	protein_coding_gene	FlyBase ID	FBgn0027660
Gene Model Status	Current	Stock availability	9 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	74B1-74B2	Sequence location	3L:17,389,131..17,414,614 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene bloated tubules is referred to in FlyBase by the symbol Dmel\blot (CG3897, FBgn0027660). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: neurotransmitter transporter activity. It is reported to be involved in the biological process: morphogenesis of an epithelium. 14 alleles are reported. The phenotypes of these alleles are annotated with: Malpighian tubule; denticle. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Sodium:neurotransmitter symporter. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult crop, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, adult spermathecae, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1626839_s_at completely aligns to an exonic region common to each of the 4 FlyBase-annotated transcript isoforms of blot. Gene sequence location is 3L:17389131..17414614.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 74B1-74B2   Limits computationally determined from genome sequence between P{PZ}Baldspot02281 and P{PZ}blot01658
Experimentally Determined Cytological Location
Cytogenetic map Notes References 74B-74B     (Johnson, 1999.6.28) 74B1-74B2   (determined by in situ hybridisation)   (Spradling et al., 1999) 74B-74B   (determined by in situ hybridisation)   (Johnson et al., 1999) 74B1-74B2     (BDGP Project Members, 1994-1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\blot for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.46 Gene model reviewed during 5.50 Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) blot-RA FBtr0075234  NM_170637   2927   769 blot-RB FBtr0075233  NM_079401   4054   976 blot-RC FBtr0075235  NM_170638   3057   809 blot-RD FBtr0075232  NM_170636   3624   976 blot-RE FBtr0339898     3089   809
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein blot-PA   FBpp0074996   86.0   769   9.29     NP_730264   AAF49348 blot-PB   FBpp0074995   107.8   976   9.21     NP_524125   AAN11707 blot-PC   FBpp0074997   91.1   809   9.18     NP_730265   AAN11709 blot-PD   FBpp0074994   107.8   976   9.21     NP_730263   AAN11708 blot-PE   FBpp0308930   91.1   809   9.18
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Sodium:neurotransmitter symporter (IPR000175)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA141175   AA952242   AE014296 AAF49348   AE014296 AAN11707   AE014296 AAN11708   AE014296 AAN11709   AJ243264 CAB53640   AW942957   AY060389 AAL25428   BF489146   BI170871   BI235890   BI237178   BI240917   BI365165   BI366244   BI368032   BI371187   BI485462   BI579585   BP560128   BT033062   BT099633   BT099677   BT133104   BT133440   CA807482   CK662345   CO192913   CO272947   CO296484   CO298950   CO314506   CO333802   CO339454   CW848241   CZ485194   CZ485195   EC071903   EC088309   EC206747   EC210818   EC220043   EC228340   EC231978   EC254834   EC257868   G00742   GH750402   GH750503   GH751078   GH751650   GH751660   GH752431   GH752531   GH754933   GH755101   GH758159   GH758943   GH759048   GH759248   GH760591   GH770929   GH771335   GH771922   GH772462   GH772613   GH773506   GH775231   GH776487   GH779057   GH780206   GH780568   GH782530   GH783318   GH783379   GH785236   GH786130   GH787165   GH789868   GH789905   GH790625   GH790764   GH791906   GH791910   GH792822   GH792967   GH793001   GH794139   GH794534   GH795191   GH795897   GH796001   GH797997   GH798563   GH799912   GH802448   GH802628   GH802897   GH803716   GH805392   GH806547   GH809499   GH810421   GH812965   GH813071   GH813307   GH813611   GH813792   GH813805   GH813932   GH815109   GH815502   GH815516   GH815995   GH818032   GH818980   GH819183   GH819210   GH819397   GH821296   GH821297   GH821568   GH822572   GH824678   GH825611   GH827609   GH828357   GH829412   GH829755   GH829859   GH830187   GH831355   GH831443   GH831746   GH832736   GH832998   GH833134   GH835503   GH836115   GH836295   GH836637   GH837369   GH838971   GH839140   GH839219   GH840985   GH841280   GH841615   GH842765   GH843727   GH843892   GH844654   GH845041   GH845659   GH847041   GH847875   GH848594   GH849827   GH849900   GH851772   GH852232   GH852287   GH852612   GH853145   GH853519   GH854437   GH854629   GH854954   GH855514   GH856430   GH857346   GH857637   GH857911   GH859243   GH859886   GH861570   GH861790   GH862325   GH862759   GH862843   GH862971   GH864303   GH864651   GH865588   GH865919   GH868026   GH868149   GH868395   GH868645   GH869084   GH869854   GH869917   GH870909   GH871723   GH872080   GH873974   GH874388   GH874559   GH874976   GH875371   GH875417   GH876165   GH876509   GH877220   GH877301   GH879847   GH881240   GH881564   GH882603   GH885056   GH885213   GH886261   GH886746   GH887254   GH887260   GH887561   GH889336   GH890343   GH895641   GH896961   GH897001   GH897170   GH897452   GH897576   GH897920   GH898483   GH899709   GH899923   GH900572   GH900804   GH901322   GH902105   GH902179   GH902548   GH902868   GH903649   GH904603   GH904759   GH904764   GH905351   GH905370   GH906705   GH906711   GH907116   GH907123   GH907364   GH911193   GH912337   GH912689   GH913021   GH913537   GH913785   GH913968   GH914764   GH915038   GH915324   GH916712   GH916726   GH917189   GH917575   GH918592   GH919997   GH921651   GH922211   GH922499   GH923631   GH924074   GH925297   GH925699   GH927504   GH929564   GH931305   GH932495   GH935110   GH936466   GH937588   GH937777   GH938956   GH939287   GH940511   GH940564   GH941031
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8IQQ6 Q8IQQ7 Q9VVG3 Q9U975 Q95T09
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 4   organism | uniform   (Johnson et al., 1999) embryonic stage 5   ectoderm | restricted   (Johnson et al., 1999) Comment:anterior cap, 3 broad stripes embryonic stage 6   ectoderm | striped   (Johnson et al., 1999) Comment:6 discontinous stripes amnioproctodeal invagination   (Johnson et al., 1999) embryonic stage 12 -- 13   Malpighian tubule tip cell primordium   (Johnson et al., 1999) embryonic stage 16   cell | subset of ventral nerve cord | segmentally repeated   (Johnson et al., 1999) antenno-maxillary complex   (Johnson et al., 1999) embryonic/larval posterior spiracle   (Johnson et al., 1999) third instar larval stage   Malpighian tubule   • cytoplasm (Johnson et al., 1999) adult stage | femaleoogenesis stage S9 -- S11   nurse cell   (Johnson et al., 1999) northern blot Stage Tissue/Position (including subcellular localization) Reference embryonic stage   organism   (Johnson et al., 1999) adult stage   adult head   (Romero-Calderon et al., 2007) adult thorax   (Romero-Calderon et al., 2007) Comment:Thorax and abdomen assayed together. Band of 1.9kb detected. adult abdomen   (Romero-Calderon et al., 2007) Comment:Thorax and abdomen assayed together. Band of 1.9kb detected.
Additional Descriptive Data
	blot transcript is detected at all embryonic stages, with highest expression at 0-3 hr AEL and 3-6 hr AEL. blot transcript is evenly distributed in early embryos. At embryonic stage 5 blot transcript is localized to an anterior cap and in three broad ectodermal stripes. At embryonic stage 6 blot transcript is expressed in five strong and one weak ectodermal stripes, which are interrupted by a ventrolateral region of non-expression. There is also a posterior-lateral stripe of expression at the rim of the amnioproctodeal invagination. By stage 13, most blot transcript expression is limited to the Malpighian tubule tip cell primordium. At stage 16, blot transcript is expressed in a segmentally repeated pattern in the ventral nerve cord, in the antennomaxillary complex, and in the posterior spiracles. (Johnson et al., 1999)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult crop, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, adult spermathecae, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    256.4 Larval Midgut    32.4 Larval Hindgut    299.2 Larval Malpighian Tubules    382.4 Larval Fat Body    60.7 Larval Salivary Gland    904.9 Larval Trachea    828.025 Larval Carcass    525.475 Adult Head    239.4 Adult Eye    486.5 Adult Brain    74.3 Adult Thoracic-Abdominal Ganglion    118.7 Adult Crop    604.8 Adult Midgut    37.6 Adult Hindgut    375.9 Adult Malpighian Tubules    236.3 Adult Fat Body    267.3 Adult Salivary Gland    701.2 Adult Heart    319 Adult VirginFemale Spermatheca    276.2 Adult InseminatedFemale Spermatheca    302.6 Adult Ovary    719 Adult Testis    93.2 Adult Male Accessory Gland    1068.1 Adult Carcass    247.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    256.4 Larval Midgut    32.4 Larval Hindgut    299.2 Larval Malpighian Tubules    382.4 Larval Fat Body    60.7 Larval Salivary Gland  (904.9) Larval Trachea  (828.025) Larval Carcass  525.475 Adult Head    239.4 Adult Eye    486.5 Adult Brain    74.3 Adult Thoracic-Abdominal Ganglion    118.7 Adult Crop  (604.8) Adult Midgut    37.6 Adult Hindgut    375.9 Adult Malpighian Tubules    236.3 Adult Fat Body    267.3 Adult Salivary Gland  (701.2) Adult Heart    319 Adult VirginFemale Spermatheca    276.2 Adult InseminatedFemale Spermatheca    302.6 Adult Ovary  (719) Adult Testis    93.2 Adult Male Accessory Gland  (1068.1) Adult Carcass    247.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    256.4 Larval Midgut    32.4 Larval Hindgut    299.2 Larval Malpighian Tubules    382.4 Larval Fat Body    60.7 Larval Salivary Gland    904.9 Larval Trachea    828.025 Larval Carcass    525.475 Adult Head    239.4 Adult Eye    486.5 Adult Brain    74.3 Adult Thoracic-Abdominal Ganglion    118.7 Adult Crop    604.8 Adult Midgut    37.6 Adult Hindgut    375.9 Adult Malpighian Tubules    236.3 Adult Fat Body    267.3 Adult Salivary Gland    701.2 Adult Heart    319 Adult VirginFemale Spermatheca    276.2 Adult InseminatedFemale Spermatheca    302.6 Adult Ovary    719 Adult Testis    93.2 Adult Male Accessory Gland  1068.1 Adult Carcass    247.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    256.4 Larval Midgut    32.4 Larval Hindgut    299.2 Larval Malpighian Tubules    382.4 Larval Fat Body    60.7 Larval Salivary Gland    904.9 Larval Trachea    828.025 Larval Carcass    525.475 Adult Head    239.4 Adult Eye    486.5 Adult Brain    74.3 Adult Thoracic-Abdominal Ganglion    118.7 Adult Crop    604.8 Adult Midgut    37.6 Adult Hindgut    375.9 Adult Malpighian Tubules    236.3 Adult Fat Body    267.3 Adult Salivary Gland    701.2 Adult Heart    319 Adult VirginFemale Spermatheca    276.2 Adult InseminatedFemale Spermatheca    302.6 Adult Ovary    719 Adult Testis    93.2 Adult Male Accessory Gland    1068.1 Adult Carcass    247.5 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    256.4 Larval Midgut    32.4 Larval Hindgut    299.2 Larval Malpighian Tubules    382.4 Larval Fat Body    60.7 Larval Salivary Gland    904.9 Larval Trachea    828.025 Larval Carcass    525.475 Adult Head    239.4 Adult Eye    486.5 Adult Brain    74.3 Adult Thoracic-Abdominal Ganglion    118.7 Adult Crop    604.8 Adult Midgut    37.6 Adult Hindgut    375.9 Adult Malpighian Tubules    236.3 Adult Fat Body    267.3 Adult Salivary Gland    701.2 Adult Heart    319 Adult VirginFemale Spermatheca    276.2 Adult InseminatedFemale Spermatheca    302.6 Adult Ovary    719 Adult Testis    93.2 Adult Male Accessory Gland    1068.1 Adult Carcass    247.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    256.4 Larval Midgut    32.4 Larval Hindgut    299.2 Larval Malpighian Tubules    382.4 Larval Fat Body    60.7 Larval Salivary Gland  (904.9) Larval Trachea  (828.025) Larval Carcass  525.475 Adult Head    239.4 Adult Eye    486.5 Adult Brain    74.3 Adult Thoracic-Abdominal Ganglion    118.7 Adult Crop  604.8 Adult Midgut    37.6 Adult Hindgut    375.9 Adult Malpighian Tubules    236.3 Adult Fat Body    267.3 Adult Salivary Gland  701.2 Adult Heart    319 Adult VirginFemale Spermatheca    276.2 Adult InseminatedFemale Spermatheca    302.6 Adult Ovary  719 Adult Testis    93.2 Adult Male Accessory Gland  (1068.1) Adult Carcass    247.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    256.4 Larval Midgut    32.4 Larval Hindgut    299.2 Larval Malpighian Tubules    382.4 Larval Fat Body    60.7 Larval Salivary Gland    904.9 Larval Trachea    828.025 Larval Carcass    525.475 Adult Head    239.4 Adult Eye    486.5 Adult Brain    74.3 Adult Thoracic-Abdominal Ganglion    118.7 Adult Crop    604.8 Adult Midgut    37.6 Adult Hindgut    375.9 Adult Malpighian Tubules    236.3 Adult Fat Body    267.3 Adult Salivary Gland    701.2 Adult Heart    319 Adult VirginFemale Spermatheca    276.2 Adult InseminatedFemale Spermatheca    302.6 Adult Ovary    719 Adult Testis    93.2 Adult Male Accessory Gland  1068.1 Adult Carcass    247.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    256.4 Larval Midgut    32.4 Larval Hindgut    299.2 Larval Malpighian Tubules    382.4 Larval Fat Body    60.7 Larval Salivary Gland    904.9 Larval Trachea    828.025 Larval Carcass    525.475 Adult Head    239.4 Adult Eye    486.5 Adult Brain    74.3 Adult Thoracic-Abdominal Ganglion    118.7 Adult Crop    604.8 Adult Midgut    37.6 Adult Hindgut    375.9 Adult Malpighian Tubules    236.3 Adult Fat Body    267.3 Adult Salivary Gland    701.2 Adult Heart    319 Adult VirginFemale Spermatheca    276.2 Adult InseminatedFemale Spermatheca    302.6 Adult Ovary    719 Adult Testis    93.2 Adult Male Accessory Gland    1068.1 Adult Carcass    247.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    239.4   NA  Eye    486.5   NA  Brain    74.3   256.4  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    118.7   NA  Crop    604.8   32.4  Midgut    37.6   299.2  Hindgut    375.9   382.4  Malpighian Tubules    236.3   60.7  Fat Body    267.3   904.9  Salivary Gland    701.2   NA  Heart    319   828.025  Trachea    NA   NA  VirginFemale Spermatheca    276.2   NA  InseminatedFemale Spermatheca    302.6   NA  Ovary    719   NA  Testis    93.2   NA  Male Accessory Gland    1068.1   525.475  Carcass    247.5 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    6 central nervous system, pupae P8    3 head, virgin 1-day female    6 head, virgin 4-day female    4 head, virgin 20-day female    4 head, mated 1-day female    5 head, mated 4-day female    4 head, mated 20-day female    3 head, mated 1-day male    8 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    16 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    7 fat body, larvae L3 wandering    1 fat body, white prepupae    5 fat body, pupae P8    3 carcass, larvae L3 wandering    15 carcass, 1-day adult    4 carcass, 4-day adult    6 carcass, 20-day adult    7 ovary, virgin 4-day female    37 ovary, mated 4-day female    26 testis, mated 4-day male    3 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    6 central nervous system, pupae P8    3 head, virgin 1-day female    6 head, virgin 4-day female    4 head, virgin 20-day female    4 head, mated 1-day female    5 head, mated 4-day female    4 head, mated 20-day female    3 head, mated 1-day male    8 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    16 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    7 fat body, larvae L3 wandering    1 fat body, white prepupae    5 fat body, pupae P8    3 carcass, larvae L3 wandering    15 carcass, 1-day adult    4 carcass, 4-day adult    6 carcass, 20-day adult    7 ovary, virgin 4-day female  (37) ovary, mated 4-day female  26 testis, mated 4-day male    3 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    6 central nervous system, pupae P8    3 head, virgin 1-day female    6 head, virgin 4-day female    4 head, virgin 20-day female    4 head, mated 1-day female    5 head, mated 4-day female    4 head, mated 20-day female    3 head, mated 1-day male    8 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    16 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    7 fat body, larvae L3 wandering    1 fat body, white prepupae    5 fat body, pupae P8    3 carcass, larvae L3 wandering    15 carcass, 1-day adult    4 carcass, 4-day adult    6 carcass, 20-day adult    7 ovary, virgin 4-day female    37 ovary, mated 4-day female    26 testis, mated 4-day male    3 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    6 central nervous system, pupae P8    3 head, virgin 1-day female    6 head, virgin 4-day female    4 head, virgin 20-day female    4 head, mated 1-day female    5 head, mated 4-day female    4 head, mated 20-day female    3 head, mated 1-day male    8 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    16 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    7 fat body, larvae L3 wandering    1 fat body, white prepupae    5 fat body, pupae P8    3 carcass, larvae L3 wandering    15 carcass, 1-day adult    4 carcass, 4-day adult    6 carcass, 20-day adult    7 ovary, virgin 4-day female    37 ovary, mated 4-day female    26 testis, mated 4-day male    3 accessory gland, mated 4-day male    13 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    6 central nervous system, pupae P8    3 head, virgin 1-day female    6 head, virgin 4-day female    4 head, virgin 20-day female    4 head, mated 1-day female    5 head, mated 4-day female    4 head, mated 20-day female    3 head, mated 1-day male    8 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    16 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    7 fat body, larvae L3 wandering    1 fat body, white prepupae    5 fat body, pupae P8    3 carcass, larvae L3 wandering    15 carcass, 1-day adult    4 carcass, 4-day adult    6 carcass, 20-day adult    7 ovary, virgin 4-day female    37 ovary, mated 4-day female    26 testis, mated 4-day male    3 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    6 central nervous system, pupae P8    3 head, virgin 1-day female    6 head, virgin 4-day female    4 head, virgin 20-day female    4 head, mated 1-day female    5 head, mated 4-day female    4 head, mated 20-day female    3 head, mated 1-day male    8 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    16 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    7 fat body, larvae L3 wandering    1 fat body, white prepupae    5 fat body, pupae P8    3 carcass, larvae L3 wandering    15 carcass, 1-day adult    4 carcass, 4-day adult    6 carcass, 20-day adult    7 ovary, virgin 4-day female  (37) ovary, mated 4-day female  26 testis, mated 4-day male    3 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    6 central nervous system, pupae P8    3 head, virgin 1-day female    6 head, virgin 4-day female    4 head, virgin 20-day female    4 head, mated 1-day female    5 head, mated 4-day female    4 head, mated 20-day female    3 head, mated 1-day male    8 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    16 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    7 fat body, larvae L3 wandering    1 fat body, white prepupae    5 fat body, pupae P8    3 carcass, larvae L3 wandering    15 carcass, 1-day adult    4 carcass, 4-day adult    6 carcass, 20-day adult    7 ovary, virgin 4-day female    37 ovary, mated 4-day female    26 testis, mated 4-day male    3 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    13 central nervous system, larvae L3    6 central nervous system, pupae P8    3 head, virgin 1-day female    6 head, virgin 4-day female    4 head, virgin 20-day female    4 head, mated 1-day female    5 head, mated 4-day female    4 head, mated 20-day female    3 head, mated 1-day male    8 head, mated 4-day male    7 head, mated 20-day male    7 salivary gland, larvae L3 wandering    13 salivary gland, white prepupae    16 digestive system, larvae L3 wandering    9 digestive system, 1-day adult    4 digestive system, 4-day adult    5 digestive system, 20-day adult    7 fat body, larvae L3 wandering    1 fat body, white prepupae    5 fat body, pupae P8    3 carcass, larvae L3 wandering    15 carcass, 1-day adult    4 carcass, 4-day adult    6 carcass, 20-day adult    7 ovary, virgin 4-day female    37 ovary, mated 4-day female    26 testis, mated 4-day male    3 accessory gland, mated 4-day male    13 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    53 embryo 02-04hr    32 embryo 04-06hr    41 embryo 06-08hr    26 embryo 08-10hr    15 embryo 10-12hr    16 embryo 12-14hr    13 embryo 14-16hr    8 embryo 16-18hr    9 embryo 18-20hr    14 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    5 larva L2    7 larva L3 12hr old    9 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    23 white prepupae new    17 white prepupae 12hr    22 white prepupae 24hr    14 pupae 2d postWPP    17 pupae 3d postWPP    7 pupae 4d postWPP    12 adult male 01day    9 adult male 05day    10 adult male 30day    9 adult female 01day    19 adult female 05day    31 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (53) embryo 02-04hr  (32) embryo 04-06hr  (41) embryo 06-08hr  26 embryo 08-10hr    15 embryo 10-12hr    16 embryo 12-14hr    13 embryo 14-16hr    8 embryo 16-18hr    9 embryo 18-20hr    14 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    5 larva L2    7 larva L3 12hr old    9 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    23 white prepupae new    17 white prepupae 12hr    22 white prepupae 24hr    14 pupae 2d postWPP    17 pupae 3d postWPP    7 pupae 4d postWPP    12 adult male 01day    9 adult male 05day    10 adult male 30day    9 adult female 01day    19 adult female 05day  (31) adult female 30day  (33) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    53 embryo 02-04hr    32 embryo 04-06hr    41 embryo 06-08hr    26 embryo 08-10hr    15 embryo 10-12hr    16 embryo 12-14hr    13 embryo 14-16hr    8 embryo 16-18hr    9 embryo 18-20hr    14 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    5 larva L2    7 larva L3 12hr old    9 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    23 white prepupae new    17 white prepupae 12hr    22 white prepupae 24hr    14 pupae 2d postWPP    17 pupae 3d postWPP    7 pupae 4d postWPP    12 adult male 01day    9 adult male 05day    10 adult male 30day    9 adult female 01day    19 adult female 05day    31 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    53 embryo 02-04hr    32 embryo 04-06hr    41 embryo 06-08hr    26 embryo 08-10hr    15 embryo 10-12hr    16 embryo 12-14hr    13 embryo 14-16hr    8 embryo 16-18hr    9 embryo 18-20hr    14 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    5 larva L2    7 larva L3 12hr old    9 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    23 white prepupae new    17 white prepupae 12hr    22 white prepupae 24hr    14 pupae 2d postWPP    17 pupae 3d postWPP    7 pupae 4d postWPP    12 adult male 01day    9 adult male 05day    10 adult male 30day    9 adult female 01day    19 adult female 05day    31 adult female 30day    33 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    53 embryo 02-04hr    32 embryo 04-06hr    41 embryo 06-08hr    26 embryo 08-10hr    15 embryo 10-12hr    16 embryo 12-14hr    13 embryo 14-16hr    8 embryo 16-18hr    9 embryo 18-20hr    14 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    5 larva L2    7 larva L3 12hr old    9 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    23 white prepupae new    17 white prepupae 12hr    22 white prepupae 24hr    14 pupae 2d postWPP    17 pupae 3d postWPP    7 pupae 4d postWPP    12 adult male 01day    9 adult male 05day    10 adult male 30day    9 adult female 01day    19 adult female 05day    31 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (53) embryo 02-04hr  32 embryo 04-06hr  (41) embryo 06-08hr  26 embryo 08-10hr    15 embryo 10-12hr    16 embryo 12-14hr    13 embryo 14-16hr    8 embryo 16-18hr    9 embryo 18-20hr    14 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    5 larva L2    7 larva L3 12hr old    9 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    23 white prepupae new    17 white prepupae 12hr    22 white prepupae 24hr    14 pupae 2d postWPP    17 pupae 3d postWPP    7 pupae 4d postWPP    12 adult male 01day    9 adult male 05day    10 adult male 30day    9 adult female 01day    19 adult female 05day  31 adult female 30day  (33) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    53 embryo 02-04hr    32 embryo 04-06hr    41 embryo 06-08hr    26 embryo 08-10hr    15 embryo 10-12hr    16 embryo 12-14hr    13 embryo 14-16hr    8 embryo 16-18hr    9 embryo 18-20hr    14 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    5 larva L2    7 larva L3 12hr old    9 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    23 white prepupae new    17 white prepupae 12hr    22 white prepupae 24hr    14 pupae 2d postWPP    17 pupae 3d postWPP    7 pupae 4d postWPP    12 adult male 01day    9 adult male 05day    10 adult male 30day    9 adult female 01day    19 adult female 05day    31 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    53 embryo 02-04hr    32 embryo 04-06hr    41 embryo 06-08hr    26 embryo 08-10hr    15 embryo 10-12hr    16 embryo 12-14hr    13 embryo 14-16hr    8 embryo 16-18hr    9 embryo 18-20hr    14 embryo 20-22hr    7 embryo 22-24hr    9 larva L1    5 larva L2    7 larva L3 12hr old    9 larva L3 puffstage 1-2    8 larva L3 puffstage 3-6    21 larva L3 puffstage 7-9    23 white prepupae new    17 white prepupae 12hr    22 white prepupae 24hr    14 pupae 2d postWPP    17 pupae 3d postWPP    7 pupae 4d postWPP    12 adult male 01day    9 adult male 05day    10 adult male 30day    9 adult female 01day    19 adult female 05day    31 adult female 30day    33 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    1 embryonic 1182-4H    0 embryonic GM2    2 embryonic Kc167    1 embryonic S1    5 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    1 wing disc ML-DmD8    2 wing disc ML-DmD9    1 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    3 CNS ML-DmBG1-c1    5 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    1 embryonic 1182-4H    0 embryonic GM2    2 embryonic Kc167    1 embryonic S1    5 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    1 wing disc ML-DmD8    2 wing disc ML-DmD9    1 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    3 CNS ML-DmBG1-c1    5 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    1 embryonic 1182-4H    0 embryonic GM2    2 embryonic Kc167    1 embryonic S1    5 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    1 wing disc ML-DmD8    2 wing disc ML-DmD9    1 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    3 CNS ML-DmBG1-c1    5 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    1 embryonic 1182-4H    0 embryonic GM2    2 embryonic Kc167    1 embryonic S1    5 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    1 wing disc ML-DmD8    2 wing disc ML-DmD9    1 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    3 CNS ML-DmBG1-c1    5 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    3 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    1 embryonic 1182-4H    0 embryonic GM2    2 embryonic Kc167    1 embryonic S1    5 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    1 wing disc ML-DmD8    2 wing disc ML-DmD9    1 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    3 CNS ML-DmBG1-c1    5 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    1 embryonic 1182-4H    0 embryonic GM2    2 embryonic Kc167    1 embryonic S1    5 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    1 wing disc ML-DmD8    2 wing disc ML-DmD9    1 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    3 CNS ML-DmBG1-c1    5 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    1 embryonic 1182-4H    0 embryonic GM2    2 embryonic Kc167    1 embryonic S1    5 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    1 wing disc ML-DmD8    2 wing disc ML-DmD9    1 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    3 CNS ML-DmBG1-c1    5 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    0 Schneider line 2 Sg4    1 embryonic 1182-4H    0 embryonic GM2    2 embryonic Kc167    1 embryonic S1    5 embryonic S3    0 leg disc CME L1    1 wing disc CME-W2    1 wing disc ML-DmD8    2 wing disc ML-DmD9    1 wing disc ML-DmD16-c3    1 wing disc ML-DmD21    1 wing disc ML-DmD32    0 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    0 mixed discs ML-DmD4-c1    3 CNS ML-DmBG1-c1    5 CNS ML-DmBG2-c2    0 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    1 ovary OSS    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    16 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    27 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    16 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3  (27) Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    16 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    27 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    16 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    27 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    16 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    27 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    16 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3  27 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    16 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    27 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    9 cold shock, 4-day adult    8 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    11 Cadmium 100 mM 48 hrs, 4-day adult    23 Copper 0.5 mM 12 hrs, larvae L3    4 Copper 15 mM 48 hrs, 4-day adult    16 Zinc 5 mM 12 hrs, larvae L3    5 Zinc 4.5 mM 48 hrs, 4-day adult    7 Ethanol 2.5% 3 hrs, larvae L3    27 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    4 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    19 Caffeine 25 mg/ml 48 hrs, 4-day adult    7 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    17 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_06 mE1_20_mRNA_expression_cluster_09
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0027660 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3897-RD
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | germline clone | non-rescuable maternal effect blot01658 blotM55 lethal | larval stage blot01658 blotM51 blotM55 lethal | recessive blot01658 viable blotEY13445 viable, with Scer\GAL4pnr-MD237 blotGD2690 Sterility Allele female fertile | germline clone | reduced blot01658 blotM55 fertile blotEY13445 Phenotype manifest in Allele blastoderm embryo | germline clone blot01658 blotM55 denticle blot01658 blotM55 Malpighian tubule blot01658 blotM55 pole cell | germline clone blot01658 blotM55
Classical Alleles ( 10 )
For All Classical Alleles Show
Allele of blot Class Mutagen Stocks Known lesion blot01658 hypomorphic allele - genetic evidence P-element activity 1 Yes blotA223 1 -- blotEY13445 P-element activity 1 -- blotf02653 piggyBac transposase 1 -- blotMI01264 1 -- blotMI05046 1 -- blotEP3241 P-element activity 0 -- blotEP3242 P-element activity 0 -- blotM51 Delta2-3 0 Yes blotM55 Delta2-3 0 Yes
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of blot Class Mutagen Stocks Known lesion blotGD2690 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes blotKK106850 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes blotGD16841 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes blotNIG.3897R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)81k19 (Johnson et al., 1999) Df(3L)BSC414 (Christensen et al., 2008.4.15) Df(3L)BSC415 (Christensen et al., 2008.4.15) Df(3L)BSC432 (Christensen et al., 2008.4.15) Df(3L)BSC444 (Christensen et al., 2008.4.15) Df(3L)Exel6131 (Ryder, 2004.4.26) Df(3L)st-E23 (Johnson et al., 1999) Df(3L)tap-74 (Johnson et al., 1999)
Not disrupted in	Df(3L)st7 (Johnson et al., 1999)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD2690} NA P{GD16841} NA P{KK106850} NA P{NIG.3897R} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{PZ}blot01658 No insertion of mobile activating element P{EP}blotEP3241 NA P{EP}blotEP3242 NA P{EPgy2}blotEY13445 NA miscellaneous insertions Mi{MIC}blotMI01264 NA Mi{MIC}blotMI05046 NA P{?lArB}blotM51 NA P{?lArB}blotM55 NA PBac{5HPw+}blotA223 NA PBac{WH}blotf02653 NA
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
neurotransmitter:sodium symporter activity inferred from electronic annotation with InterPro:IPR000175 (FlyBase Curators et al., 2004-) neurotransmitter transporter activity non-traceable author statement (Johnson, 1999.6.28)
Biological Process
CV term Evidence References
morphogenesis of an epithelium traceable author statement (Tepass et al., 2001) neurotransmitter transport inferred from electronic annotation with InterPro:IPR000175 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR000175 (FlyBase Curators et al., 2004-) non-traceable author statement (Tepass et al., 2001)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions blot allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 65229 DroID - A comprehensive database of gene and protein interactions. • FBgn0027660 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39939
Orthologs
OrthoDB Orthologs (21) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG61ZFW8 Dipteran inclusive ortholog search EOG6S1TG6 Insect inclusive ortholog search EOG6SBCSW Arthropod inclusive ortholog search EOG6ZW3S0 Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG61ZFW8)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\blot     Drosophila simulans   Dsim\GD12410 Y   Drosophila sechellia   Dsec\GM24336 Y   Drosophila erecta   Dere\GG15815 Y   Drosophila yakuba   Dyak\GE22154 Y   Drosophila ananassae   Dana\GF24313 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA23839 Y   Drosophila persimilis   Dper\GL15489     Drosophila willistoni   Dwil\GK17562 Y   Drosophila virilis   Dvir\GJ13029     Drosophila mojavensis   Dmoj\GI12888 Y   Drosophila grimshawi   Dgri\GH14911 Y
Orthologs in non-Drosophila Dipterans (EOG6S1TG6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL014927   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL010883   Anopheles gambiae Malaria mosquito  Agam\AGAP004932   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ009884   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ009883
Orthologs in non-Dipteran Insects (EOG6SBCSW)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Acyrthosiphon pisum Pea aphid  Apim\ACYPI21790   Bombyx mori Silkmoth  Bmor\BGIBMGA010528   Tribolium castaneum Red flour beetle  Tcas\TC003241
Orthologs in non-Insect Arthropods (EOG6ZW3S0)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Ixodes scapularis Deer tick  Isca\ISCW001112
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (9) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD12410 Drosophila sechellia Dsec\GM24336 Drosophila erecta Dere\GG15815 Drosophila yakuba Dyak\GE22154 Drosophila ananassae Dana\GF24313 Drosophila pseudoobscura pseudoobscura Dpse\GA23839 Drosophila willistoni Dwil\GK17562 Drosophila mojavensis Dmoj\GI12888 Drosophila grimshawi Dgri\GH14911
Stocks & Reagents
Stocks Listed in FlyBase ( 9 )
Bloomington	21417 y1 w67c23; P{EPgy2}blotEY13445 34416 y1 w*; Mi{MIC}blotMI01264/TM3, Sb1 Ser1 38188 y1 w*; Mi{MIC}blotMI05046/TM3, Sb1 Ser1 16070 y1 w1118; PBac{5HPw+}blotA223/TM3, Sb1 Ser1 11542 tap01658 P{PZ}blot01658 ry506/TM3, ryRK Sb1 Ser1
Harvard	- PBac{WH}blotf02653
VDRC	v101083 P{KK106850}VIE-260B v5296 w1118; P{GD2690}v5296 v5297 w1118; P{GD2690}v5297/CyO
Genomic Clones ( 1 )
	BACR22B18 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 272 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD29349 LP03078 RE26220 RE55478
Other clones	FI18175 FI20161
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT24861 LP22473 RE12474 RE31841 RE33356 RE37876 RE50401 RE51742 RE53934 RE58033 RE68786 RE73643
Other clones	9870 43022 117366 214251.20 214343.61 281948 CK01.49A.C8 CK01.124C.F3 CK01.144A.F5 CK01325 EC34770 EK108936 EK174156 EK213808 EK236726 EK308016 EP02031 ESG018a.E21_G06 FGM324G11 RP003002396 RP003006989 RP003007755 RP003009847 RP003010363 RP003016791 RP003016903 RP003023295 RP003023496 RP003027281 RP003027738 RP003030604 RP003034483 RP003037309 RP003039708 RP003040876 RP003043215 RP003048675 RP003050452 RP003052128 RP003052625 RP003052935 RP003056665 RP003059244 RP003061088 RP003070403 RP003071618 RP003072566 RP003077891 RP003083257 RP003086995 RP003087173 RP003087290 RP003088791 RP003090913 RP003093248 RP003094407 RP003098162 RP003098349 RP003104695 RP003108339 RP003109391 RP003110183 RP003113854 RP003117436 RP003117525 RP003119058 RP003119357 RP003124285 RP003126528 RP003128635 RP003129073 RP003129835 RP003129939 RP003132876 RP003133253 RP003135838 RP003139573 RP003142463 RP003144412 RP003144415 RP003146662 RP003147004 RP003153143 RP003158923 RP003161767 RP003164799 RP003164813 RP003166928 RP003170495 RP003179654 RP003180697 RP003186548 RP003195573 RP003197471 RP003198130 RP003199463 RP003201139 RP003203161 RP003204354 RP003207688 RP003209134 RP003209635 RP003209714 RP003214918 RP003215108 RP003215207 RP003218868 RP003220025 RP003228062 RP003230223 RP003232509 RP003236071 RP003238922 RP003238955 RP003239855 RP003243134 RP003247612 RP003247918 RP003249344 RP003251762 RP003252481 RP003254254 RP003254476 RP003257415 RP003260790 RP003261809 RP003263931 RP003265095 RP003266481 RP003273059 RP003275168 RP003279904 RP003280863 RP003289559 RP003290010 RP003295412 RP003296682 RP003297165 RP003297751 RP003306719 RP003311661 RP003312229 RP003312540 RP003312789 RP003313070 RP003315126 RP003323306 RP003325036 RP003325319 RP003325473 RP003326134 RP003326841 RP003329387 RP003333831 RP003344109 RP003346068 RP003346931 RP003347385 RP003347842 RP003348567 RP003349608 RP003350159 RP003350699 RP003352788 RP003352934 RP003367370 RP003371205 RP003372686 RP003386178 RP003386319 RP003390962 RP003398707 RP003399117 RP003406730 RP003413833 RP003413992 RP003419396 RP003422883 RP003435525 RP003437975 RP003444759 RP003447121 RP003455560 RP003461998 RP003464071 RP003466951 RP003467560 RP003472642 RP003475385 RP003478524 RP003487753 RP003490971 RP003495457 RP003502043 RP003508648 RP003508706 RP003509144 RP003513050 RP003515015 RP003515918 RP003517738 RP003522847 RP003523414 RP003527260 RP003527794 RP003531548 RP003535417 RP003536804 RP003537772 RP003538750 RP003540811 RP003550263 RP003551683 RP003555152 RP003555170 RP003560991 RP003561011 RP003563794 RP003564509 RP003571952 RP003578650 RP003579289 RP003582424 RP003585511 RP003592003 RP003595975 RP003596871 RP003601043 RP003603363 RP003611544 RP003614465 RP003619061 RP003627462 RP003628038 RP003631729 RP003637616 RP003639479 RP003643230 RP003660224 RP003661897 RP003663303 RP003663970 RP003664352 RP003666299 RP003667262 RP003668826 RP003671025 RP003672077 RP003672407 RP003672974 RP003673911 RP003674620 RP003682093 RP003682098
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0027660 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39939
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments	Comparison of restriction maps for the genomic regions of tap and blot reveals no overlap. Whole mount in situ hybridization with fragments of the blot walk do not stain tap- expressing cells. tap and blot therefore have distinctive genomic organizations. (Johnson et al., 1999)
Other Comments
	blot is required for viability. Mutants show defects in the Malpighian tubule cells of larvae, and the actin filaments in the apical cortex and the cortical cytoskeleton of embryos, and the cellularisation process. (Johnson et al., 1999)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079401 NM_170636 NM_170637 NM_170638 RefSeq (Proteins) • NP_524125 NP_730263 NP_730264 NP_730265 DDBJ / EMBL / GenBank • AA952242 AAF49348 AAL25428 AAN11707 AAN11708 AAN11709 AJ243264 AW942957 AY060389 CAB53640 CW848241 CZ485194 CZ485195 G00742 Entrez Gene - A searchable database of RefSeq genes. • 39939 UniProtKB/TrEMBL • Q8IQQ6 Q8IQQ7 Q9U975 Q9VVG3 Q95T09
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Sodium:neurotransmitter symporter (IPR000175)
Linkouts
	BioGRID - A database of protein and genetic interactions • 65229 DroID - A comprehensive database of gene and protein interactions. • FBgn0027660 DRSC - Results from RNAi screens. • FBgn0027660 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0027660 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG3897-RD FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0027660 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 39939 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 39939 modMine - Data generated by the modENCODE project. • FBgn0027660
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	blot (Christensen et al., 2008.4.15, Arancio et al., 2010, Christensen et al., 2008.4.15, Christensen et al., 2008.4.15, Christensen et al., 2008.4.15, Romero-Calderon et al., 2007, Thimgan et al., 2006, Japanese National Institute of Genetics, 2012.5.21) CG3897 (Miller et al., 2008, Keleman et al., 2009.8.5, Romero-Calderon et al., 2007) DmBLOT (Miller et al., 2008) l(3)1658 (Johnson et al., 1999)
Name Synonym	Blated tubules (Sano et al., 2005) bloated tubules (Thimgan et al., 2006)
Secondary FlyBase IDs
References ( 39 )
Generate a list of	All references relating to this gene ( 39 )
List References by type	Research paper  ( 11 ) Supplementary material  ( 5 ) Review  ( 1 ) Personal communication to FlyBase  ( 15 ) FlyBase analysis  ( 3 ) Stock list  ( 1 ) DNA/RNA sequence record  ( 1 ) Curated genome annotation  ( 2 )
Recent research papers ( 1 )
	Weber et al., 2012, PLoS ONE 7(4): e34745 Genome-Wide Association Analysis of Oxidative Stress Resistance in Drosophila melanogaster. [FBrf0218073] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...