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Gene Dmel\O-fut2

General Information
Symbol	Dmel\O-fut2	Species	D. melanogaster
Name	O-fucosyltransferase 2	Annotation symbol	CG14789
Feature type	protein_coding_gene	FlyBase ID	FBgn0027791
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	2A4-2A4	Sequence location	X:1,358,396..1,360,029 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene O-fucosyltransferase 2 is referred to in FlyBase by the symbol Dmel\O-fut2 (CG14789, FBgn0027791). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: peptide-O-fucosyltransferase activity. There is experimental evidence that it is involved in the biological process: O-glycan processing. 9 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: GDP-fucose protein O-fucosyltransferase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, adult female reproductive system, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1629180_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of O-fut2. Gene sequence location is X:1358396..1360029.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 2A4-2A4   Limits computationally determined from genome sequence between P{EP}futschEP1419 and P{EP}brEP1515
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\O-fut2 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.49
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) O-fut2-RA FBtr0070296  NM_130560   1634   490
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein O-fut2-PA   FBpp0070283   56.0   490   8.21     NP_569916   AAF45629
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • GDP-fucose protein O-fucosyltransferase (IPR019378)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA696228   AE014298 AAF45629   AI108705   AI296982   AI402112   AI404976   AL035632 CAB53644   AY047568 AAK77300   BI216729   BI633229   BI638645   EL875737   EL875884   EL875885   EL876012   EL876013   EL876136   EL876137   EV575593   EV576785
UniProtKB/Swiss-Prot	Q9W589
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
endoplasmic reticulum inferred from direct assay (assigned by UniProtKB) (Luo et al., 2006)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, adult female reproductive system, adult male accessory gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    157.2 Larval Midgut    82 Larval Hindgut    73.7 Larval Malpighian Tubules    195.7 Larval Fat Body    116.3 Larval Salivary Gland    120.4 Larval Trachea    91.05 Larval Carcass    73.075 Adult Head    65.7 Adult Eye    90.775 Adult Brain    44.9 Adult Thoracic-Abdominal Ganglion    57.1 Adult Crop    38.1 Adult Midgut    72.5 Adult Hindgut    51 Adult Malpighian Tubules    130.3 Adult Fat Body    109.9 Adult Salivary Gland    375.8 Adult Heart    114.45 Adult VirginFemale Spermatheca    135.3 Adult InseminatedFemale Spermatheca    137.8 Adult Ovary    134.7 Adult Testis    21.5 Adult Male Accessory Gland    482.4 Adult Carcass    75.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    157.2 Larval Midgut    82 Larval Hindgut    73.7 Larval Malpighian Tubules    195.7 Larval Fat Body    116.3 Larval Salivary Gland    120.4 Larval Trachea    91.05 Larval Carcass    73.075 Adult Head    65.7 Adult Eye    90.775 Adult Brain    44.9 Adult Thoracic-Abdominal Ganglion    57.1 Adult Crop    38.1 Adult Midgut    72.5 Adult Hindgut    51 Adult Malpighian Tubules    130.3 Adult Fat Body    109.9 Adult Salivary Gland    375.8 Adult Heart    114.45 Adult VirginFemale Spermatheca    135.3 Adult InseminatedFemale Spermatheca    137.8 Adult Ovary    134.7 Adult Testis    21.5 Adult Male Accessory Gland    482.4 Adult Carcass    75.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    157.2 Larval Midgut    82 Larval Hindgut    73.7 Larval Malpighian Tubules    195.7 Larval Fat Body    116.3 Larval Salivary Gland    120.4 Larval Trachea    91.05 Larval Carcass    73.075 Adult Head    65.7 Adult Eye    90.775 Adult Brain    44.9 Adult Thoracic-Abdominal Ganglion    57.1 Adult Crop    38.1 Adult Midgut    72.5 Adult Hindgut    51 Adult Malpighian Tubules    130.3 Adult Fat Body    109.9 Adult Salivary Gland    375.8 Adult Heart    114.45 Adult VirginFemale Spermatheca    135.3 Adult InseminatedFemale Spermatheca    137.8 Adult Ovary    134.7 Adult Testis    21.5 Adult Male Accessory Gland    482.4 Adult Carcass    75.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    157.2 Larval Midgut    82 Larval Hindgut    73.7 Larval Malpighian Tubules    195.7 Larval Fat Body    116.3 Larval Salivary Gland    120.4 Larval Trachea    91.05 Larval Carcass    73.075 Adult Head    65.7 Adult Eye    90.775 Adult Brain    44.9 Adult Thoracic-Abdominal Ganglion    57.1 Adult Crop    38.1 Adult Midgut    72.5 Adult Hindgut    51 Adult Malpighian Tubules    130.3 Adult Fat Body    109.9 Adult Salivary Gland    375.8 Adult Heart    114.45 Adult VirginFemale Spermatheca    135.3 Adult InseminatedFemale Spermatheca    137.8 Adult Ovary    134.7 Adult Testis    21.5 Adult Male Accessory Gland    482.4 Adult Carcass    75.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    157.2 Larval Midgut    82 Larval Hindgut    73.7 Larval Malpighian Tubules    195.7 Larval Fat Body    116.3 Larval Salivary Gland    120.4 Larval Trachea    91.05 Larval Carcass    73.075 Adult Head    65.7 Adult Eye    90.775 Adult Brain    44.9 Adult Thoracic-Abdominal Ganglion    57.1 Adult Crop    38.1 Adult Midgut    72.5 Adult Hindgut    51 Adult Malpighian Tubules    130.3 Adult Fat Body    109.9 Adult Salivary Gland    375.8 Adult Heart    114.45 Adult VirginFemale Spermatheca    135.3 Adult InseminatedFemale Spermatheca    137.8 Adult Ovary    134.7 Adult Testis    21.5 Adult Male Accessory Gland    482.4 Adult Carcass    75.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    157.2 Larval Midgut    82 Larval Hindgut    73.7 Larval Malpighian Tubules    195.7 Larval Fat Body    116.3 Larval Salivary Gland    120.4 Larval Trachea    91.05 Larval Carcass    73.075 Adult Head    65.7 Adult Eye    90.775 Adult Brain    44.9 Adult Thoracic-Abdominal Ganglion    57.1 Adult Crop    38.1 Adult Midgut    72.5 Adult Hindgut    51 Adult Malpighian Tubules    130.3 Adult Fat Body    109.9 Adult Salivary Gland    375.8 Adult Heart    114.45 Adult VirginFemale Spermatheca    135.3 Adult InseminatedFemale Spermatheca    137.8 Adult Ovary    134.7 Adult Testis    21.5 Adult Male Accessory Gland    482.4 Adult Carcass    75.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    157.2 Larval Midgut    82 Larval Hindgut    73.7 Larval Malpighian Tubules    195.7 Larval Fat Body    116.3 Larval Salivary Gland    120.4 Larval Trachea    91.05 Larval Carcass    73.075 Adult Head    65.7 Adult Eye    90.775 Adult Brain    44.9 Adult Thoracic-Abdominal Ganglion    57.1 Adult Crop    38.1 Adult Midgut    72.5 Adult Hindgut    51 Adult Malpighian Tubules    130.3 Adult Fat Body    109.9 Adult Salivary Gland    375.8 Adult Heart    114.45 Adult VirginFemale Spermatheca    135.3 Adult InseminatedFemale Spermatheca    137.8 Adult Ovary    134.7 Adult Testis    21.5 Adult Male Accessory Gland    482.4 Adult Carcass    75.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    157.2 Larval Midgut    82 Larval Hindgut    73.7 Larval Malpighian Tubules    195.7 Larval Fat Body    116.3 Larval Salivary Gland    120.4 Larval Trachea    91.05 Larval Carcass    73.075 Adult Head    65.7 Adult Eye    90.775 Adult Brain    44.9 Adult Thoracic-Abdominal Ganglion    57.1 Adult Crop    38.1 Adult Midgut    72.5 Adult Hindgut    51 Adult Malpighian Tubules    130.3 Adult Fat Body    109.9 Adult Salivary Gland    375.8 Adult Heart    114.45 Adult VirginFemale Spermatheca    135.3 Adult InseminatedFemale Spermatheca    137.8 Adult Ovary    134.7 Adult Testis    21.5 Adult Male Accessory Gland    482.4 Adult Carcass    75.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    65.7   NA  Eye    90.775   NA  Brain    44.9   157.2  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    57.1   NA  Crop    38.1   82  Midgut    72.5   73.7  Hindgut    51   195.7  Malpighian Tubules    130.3   116.3  Fat Body    109.9   120.4  Salivary Gland    375.8   NA  Heart    114.45   91.05  Trachea    NA   NA  VirginFemale Spermatheca    135.3   NA  InseminatedFemale Spermatheca    137.8   NA  Ovary    134.7   NA  Testis    21.5   NA  Male Accessory Gland    482.4   73.075  Carcass    75.9 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    11 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    4 head, virgin 20-day female    5 head, mated 1-day female    3 head, mated 4-day female    3 head, mated 20-day female    4 head, mated 1-day male    3 head, mated 4-day male    4 head, mated 20-day male    4 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    7 digestive system, 4-day adult    5 digestive system, 20-day adult    9 fat body, larvae L3 wandering    7 fat body, white prepupae    4 fat body, pupae P8    12 carcass, larvae L3 wandering    5 carcass, 1-day adult    2 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    18 ovary, mated 4-day female    16 testis, mated 4-day male    13 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    11 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    4 head, virgin 20-day female    5 head, mated 1-day female    3 head, mated 4-day female    3 head, mated 20-day female    4 head, mated 1-day male    3 head, mated 4-day male    4 head, mated 20-day male    4 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    7 digestive system, 4-day adult    5 digestive system, 20-day adult    9 fat body, larvae L3 wandering    7 fat body, white prepupae    4 fat body, pupae P8    12 carcass, larvae L3 wandering    5 carcass, 1-day adult    2 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    18 ovary, mated 4-day female    16 testis, mated 4-day male    13 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    11 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    4 head, virgin 20-day female    5 head, mated 1-day female    3 head, mated 4-day female    3 head, mated 20-day female    4 head, mated 1-day male    3 head, mated 4-day male    4 head, mated 20-day male    4 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    7 digestive system, 4-day adult    5 digestive system, 20-day adult    9 fat body, larvae L3 wandering    7 fat body, white prepupae    4 fat body, pupae P8    12 carcass, larvae L3 wandering    5 carcass, 1-day adult    2 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    18 ovary, mated 4-day female    16 testis, mated 4-day male    13 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    11 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    4 head, virgin 20-day female    5 head, mated 1-day female    3 head, mated 4-day female    3 head, mated 20-day female    4 head, mated 1-day male    3 head, mated 4-day male    4 head, mated 20-day male    4 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    7 digestive system, 4-day adult    5 digestive system, 20-day adult    9 fat body, larvae L3 wandering    7 fat body, white prepupae    4 fat body, pupae P8    12 carcass, larvae L3 wandering    5 carcass, 1-day adult    2 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    18 ovary, mated 4-day female    16 testis, mated 4-day male    13 accessory gland, mated 4-day male    18 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    11 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    4 head, virgin 20-day female    5 head, mated 1-day female    3 head, mated 4-day female    3 head, mated 20-day female    4 head, mated 1-day male    3 head, mated 4-day male    4 head, mated 20-day male    4 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    7 digestive system, 4-day adult    5 digestive system, 20-day adult    9 fat body, larvae L3 wandering    7 fat body, white prepupae    4 fat body, pupae P8    12 carcass, larvae L3 wandering    5 carcass, 1-day adult    2 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    18 ovary, mated 4-day female    16 testis, mated 4-day male    13 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    11 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    4 head, virgin 20-day female    5 head, mated 1-day female    3 head, mated 4-day female    3 head, mated 20-day female    4 head, mated 1-day male    3 head, mated 4-day male    4 head, mated 20-day male    4 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    7 digestive system, 4-day adult    5 digestive system, 20-day adult    9 fat body, larvae L3 wandering    7 fat body, white prepupae    4 fat body, pupae P8    12 carcass, larvae L3 wandering    5 carcass, 1-day adult    2 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    18 ovary, mated 4-day female    16 testis, mated 4-day male    13 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    11 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    4 head, virgin 20-day female    5 head, mated 1-day female    3 head, mated 4-day female    3 head, mated 20-day female    4 head, mated 1-day male    3 head, mated 4-day male    4 head, mated 20-day male    4 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    7 digestive system, 4-day adult    5 digestive system, 20-day adult    9 fat body, larvae L3 wandering    7 fat body, white prepupae    4 fat body, pupae P8    12 carcass, larvae L3 wandering    5 carcass, 1-day adult    2 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    18 ovary, mated 4-day female    16 testis, mated 4-day male    13 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    7 central nervous system, larvae L3    11 central nervous system, pupae P8    3 head, virgin 1-day female    2 head, virgin 4-day female    4 head, virgin 20-day female    5 head, mated 1-day female    3 head, mated 4-day female    3 head, mated 20-day female    4 head, mated 1-day male    3 head, mated 4-day male    4 head, mated 20-day male    4 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    4 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    7 digestive system, 4-day adult    5 digestive system, 20-day adult    9 fat body, larvae L3 wandering    7 fat body, white prepupae    4 fat body, pupae P8    12 carcass, larvae L3 wandering    5 carcass, 1-day adult    2 carcass, 4-day adult    4 carcass, 20-day adult    4 ovary, virgin 4-day female    18 ovary, mated 4-day female    16 testis, mated 4-day male    13 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    39 embryo 02-04hr    13 embryo 04-06hr    22 embryo 06-08hr    22 embryo 08-10hr    15 embryo 10-12hr    15 embryo 12-14hr    6 embryo 14-16hr    8 embryo 16-18hr    5 embryo 18-20hr    7 embryo 20-22hr    5 embryo 22-24hr    4 larva L1    8 larva L2    8 larva L3 12hr old    12 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    9 white prepupae new    8 white prepupae 12hr    10 white prepupae 24hr    13 pupae 2d postWPP    7 pupae 3d postWPP    5 pupae 4d postWPP    8 adult male 01day    8 adult male 05day    11 adult male 30day    12 adult female 01day    21 adult female 05day    24 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (39) embryo 02-04hr    13 embryo 04-06hr    22 embryo 06-08hr    22 embryo 08-10hr    15 embryo 10-12hr    15 embryo 12-14hr    6 embryo 14-16hr    8 embryo 16-18hr    5 embryo 18-20hr    7 embryo 20-22hr    5 embryo 22-24hr    4 larva L1    8 larva L2    8 larva L3 12hr old    12 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    9 white prepupae new    8 white prepupae 12hr    10 white prepupae 24hr    13 pupae 2d postWPP    7 pupae 3d postWPP    5 pupae 4d postWPP    8 adult male 01day    8 adult male 05day    11 adult male 30day    12 adult female 01day    21 adult female 05day    24 adult female 30day  (28) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    39 embryo 02-04hr    13 embryo 04-06hr    22 embryo 06-08hr    22 embryo 08-10hr    15 embryo 10-12hr    15 embryo 12-14hr    6 embryo 14-16hr    8 embryo 16-18hr    5 embryo 18-20hr    7 embryo 20-22hr    5 embryo 22-24hr    4 larva L1    8 larva L2    8 larva L3 12hr old    12 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    9 white prepupae new    8 white prepupae 12hr    10 white prepupae 24hr    13 pupae 2d postWPP    7 pupae 3d postWPP    5 pupae 4d postWPP    8 adult male 01day    8 adult male 05day    11 adult male 30day    12 adult female 01day    21 adult female 05day    24 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    39 embryo 02-04hr    13 embryo 04-06hr    22 embryo 06-08hr    22 embryo 08-10hr    15 embryo 10-12hr    15 embryo 12-14hr    6 embryo 14-16hr    8 embryo 16-18hr    5 embryo 18-20hr    7 embryo 20-22hr    5 embryo 22-24hr    4 larva L1    8 larva L2    8 larva L3 12hr old    12 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    9 white prepupae new    8 white prepupae 12hr    10 white prepupae 24hr    13 pupae 2d postWPP    7 pupae 3d postWPP    5 pupae 4d postWPP    8 adult male 01day    8 adult male 05day    11 adult male 30day    12 adult female 01day    21 adult female 05day    24 adult female 30day    28 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    39 embryo 02-04hr    13 embryo 04-06hr    22 embryo 06-08hr    22 embryo 08-10hr    15 embryo 10-12hr    15 embryo 12-14hr    6 embryo 14-16hr    8 embryo 16-18hr    5 embryo 18-20hr    7 embryo 20-22hr    5 embryo 22-24hr    4 larva L1    8 larva L2    8 larva L3 12hr old    12 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    9 white prepupae new    8 white prepupae 12hr    10 white prepupae 24hr    13 pupae 2d postWPP    7 pupae 3d postWPP    5 pupae 4d postWPP    8 adult male 01day    8 adult male 05day    11 adult male 30day    12 adult female 01day    21 adult female 05day    24 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (39) embryo 02-04hr    13 embryo 04-06hr    22 embryo 06-08hr    22 embryo 08-10hr    15 embryo 10-12hr    15 embryo 12-14hr    6 embryo 14-16hr    8 embryo 16-18hr    5 embryo 18-20hr    7 embryo 20-22hr    5 embryo 22-24hr    4 larva L1    8 larva L2    8 larva L3 12hr old    12 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    9 white prepupae new    8 white prepupae 12hr    10 white prepupae 24hr    13 pupae 2d postWPP    7 pupae 3d postWPP    5 pupae 4d postWPP    8 adult male 01day    8 adult male 05day    11 adult male 30day    12 adult female 01day    21 adult female 05day    24 adult female 30day  28 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    39 embryo 02-04hr    13 embryo 04-06hr    22 embryo 06-08hr    22 embryo 08-10hr    15 embryo 10-12hr    15 embryo 12-14hr    6 embryo 14-16hr    8 embryo 16-18hr    5 embryo 18-20hr    7 embryo 20-22hr    5 embryo 22-24hr    4 larva L1    8 larva L2    8 larva L3 12hr old    12 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    9 white prepupae new    8 white prepupae 12hr    10 white prepupae 24hr    13 pupae 2d postWPP    7 pupae 3d postWPP    5 pupae 4d postWPP    8 adult male 01day    8 adult male 05day    11 adult male 30day    12 adult female 01day    21 adult female 05day    24 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    39 embryo 02-04hr    13 embryo 04-06hr    22 embryo 06-08hr    22 embryo 08-10hr    15 embryo 10-12hr    15 embryo 12-14hr    6 embryo 14-16hr    8 embryo 16-18hr    5 embryo 18-20hr    7 embryo 20-22hr    5 embryo 22-24hr    4 larva L1    8 larva L2    8 larva L3 12hr old    12 larva L3 puffstage 1-2    10 larva L3 puffstage 3-6    11 larva L3 puffstage 7-9    9 white prepupae new    8 white prepupae 12hr    10 white prepupae 24hr    13 pupae 2d postWPP    7 pupae 3d postWPP    5 pupae 4d postWPP    8 adult male 01day    8 adult male 05day    11 adult male 30day    12 adult female 01day    21 adult female 05day    24 adult female 30day    28 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    69 Schneider line 2 Sg4    89 embryonic 1182-4H    42 embryonic GM2    26 embryonic Kc167    22 embryonic S1    36 embryonic S3    29 leg disc CME L1    45 wing disc CME-W2    43 wing disc ML-DmD8    97 wing disc ML-DmD9    54 wing disc ML-DmD16-c3    25 wing disc ML-DmD21    91 wing disc ML-DmD32    47 haltere disc ML-DmD17-c3    60 eye-antennal disc ML-DmD11    96 antennal disc ML-DmD20-c5    67 mixed discs ML-DmD4-c1    37 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    28 tumorous blood cells mbn2    22 ovary fGS/OSS    22 ovary OSC    17 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (69) Schneider line 2 Sg4  (89) embryonic 1182-4H  (42) embryonic GM2  26 embryonic Kc167    22 embryonic S1  (36) embryonic S3  (29) leg disc CME L1  (45) wing disc CME-W2  (43) wing disc ML-DmD8  (97) wing disc ML-DmD9  (54) wing disc ML-DmD16-c3    25 wing disc ML-DmD21  (91) wing disc ML-DmD32  (47) haltere disc ML-DmD17-c3  (60) eye-antennal disc ML-DmD11  (96) antennal disc ML-DmD20-c5  (67) mixed discs ML-DmD4-c1  (37) CNS ML-DmBG1-c1  (27) CNS ML-DmBG2-c2  (28) tumorous blood cells mbn2    22 ovary fGS/OSS    22 ovary OSC    17 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    69 Schneider line 2 Sg4    89 embryonic 1182-4H    42 embryonic GM2    26 embryonic Kc167    22 embryonic S1    36 embryonic S3    29 leg disc CME L1    45 wing disc CME-W2    43 wing disc ML-DmD8    97 wing disc ML-DmD9    54 wing disc ML-DmD16-c3    25 wing disc ML-DmD21    91 wing disc ML-DmD32    47 haltere disc ML-DmD17-c3    60 eye-antennal disc ML-DmD11    96 antennal disc ML-DmD20-c5    67 mixed discs ML-DmD4-c1    37 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    28 tumorous blood cells mbn2    22 ovary fGS/OSS    22 ovary OSC    17 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    69 Schneider line 2 Sg4    89 embryonic 1182-4H    42 embryonic GM2    26 embryonic Kc167    22 embryonic S1    36 embryonic S3    29 leg disc CME L1    45 wing disc CME-W2    43 wing disc ML-DmD8    97 wing disc ML-DmD9    54 wing disc ML-DmD16-c3    25 wing disc ML-DmD21    91 wing disc ML-DmD32    47 haltere disc ML-DmD17-c3    60 eye-antennal disc ML-DmD11    96 antennal disc ML-DmD20-c5    67 mixed discs ML-DmD4-c1    37 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    28 tumorous blood cells mbn2    22 ovary fGS/OSS    22 ovary OSC    17 ovary OSS    9 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    69 Schneider line 2 Sg4    89 embryonic 1182-4H    42 embryonic GM2    26 embryonic Kc167    22 embryonic S1    36 embryonic S3    29 leg disc CME L1    45 wing disc CME-W2    43 wing disc ML-DmD8    97 wing disc ML-DmD9    54 wing disc ML-DmD16-c3    25 wing disc ML-DmD21    91 wing disc ML-DmD32    47 haltere disc ML-DmD17-c3    60 eye-antennal disc ML-DmD11    96 antennal disc ML-DmD20-c5    67 mixed discs ML-DmD4-c1    37 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    28 tumorous blood cells mbn2    22 ovary fGS/OSS    22 ovary OSC    17 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (69) Schneider line 2 Sg4  (89) embryonic 1182-4H  (42) embryonic GM2  26 embryonic Kc167    22 embryonic S1  (36) embryonic S3  29 leg disc CME L1  (45) wing disc CME-W2  (43) wing disc ML-DmD8  (97) wing disc ML-DmD9  (54) wing disc ML-DmD16-c3    25 wing disc ML-DmD21  (91) wing disc ML-DmD32  (47) haltere disc ML-DmD17-c3  (60) eye-antennal disc ML-DmD11  (96) antennal disc ML-DmD20-c5  (67) mixed discs ML-DmD4-c1  (37) CNS ML-DmBG1-c1  27 CNS ML-DmBG2-c2  28 tumorous blood cells mbn2    22 ovary fGS/OSS    22 ovary OSC    17 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    69 Schneider line 2 Sg4    89 embryonic 1182-4H    42 embryonic GM2    26 embryonic Kc167    22 embryonic S1    36 embryonic S3    29 leg disc CME L1    45 wing disc CME-W2    43 wing disc ML-DmD8    97 wing disc ML-DmD9    54 wing disc ML-DmD16-c3    25 wing disc ML-DmD21    91 wing disc ML-DmD32    47 haltere disc ML-DmD17-c3    60 eye-antennal disc ML-DmD11    96 antennal disc ML-DmD20-c5    67 mixed discs ML-DmD4-c1    37 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    28 tumorous blood cells mbn2    22 ovary fGS/OSS    22 ovary OSC    17 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    69 Schneider line 2 Sg4    89 embryonic 1182-4H    42 embryonic GM2    26 embryonic Kc167    22 embryonic S1    36 embryonic S3    29 leg disc CME L1    45 wing disc CME-W2    43 wing disc ML-DmD8    97 wing disc ML-DmD9    54 wing disc ML-DmD16-c3    25 wing disc ML-DmD21    91 wing disc ML-DmD32    47 haltere disc ML-DmD17-c3    60 eye-antennal disc ML-DmD11    96 antennal disc ML-DmD20-c5    67 mixed discs ML-DmD4-c1    37 CNS ML-DmBG1-c1    27 CNS ML-DmBG2-c2    28 tumorous blood cells mbn2    22 ovary fGS/OSS    22 ovary OSC    17 ovary OSS    9 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    8 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    8 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    8 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    8 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    8 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    8 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    8 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    5 heat shock, 4-day adult    10 Cadmium 50 mM 6 hrs, larvae L3    11 Cadmium 50 mM 12 hrs, larvae L3    6 Cadmium 50 mM 48 hrs, 4-day adult    8 Cadmium 100 mM 48 hrs, 4-day adult    12 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    2 Ethanol 2.5% 3 hrs, larvae L3    17 Ethanol 5% 3 hrs, larvae L3    7 Ethanol 10% 3 hrs, larvae L3    7 Caffeine 1.5 mg/ml 4 hrs, larvae L3    7 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    11 Caffeine 25 mg/ml 48 hrs, 4-day adult    4 Paraquat 5 mM 48 hrs, 4-day adult    15 Paraquat 10 mM 48 hrs, 4-day adult    15 Rotenone 2 μg 12 hrs, larvae L3    7 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_06 mE1_20_mRNA_expression_cluster_05
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0027791 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14789-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable O-fut2e01659 viable, with Scer\GAL4pnr-MD237 O-fut2GD6370 Sterility Allele fertile O-fut2e01659 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of O-fut2 Class Mutagen Stocks Known lesion O-fut2e01659 piggyBac transposase 2 -- O-fut25.2c recombination 1 Yes
Alleles Carried on Transgenic Constructs ( 7 )
For All Alleles Carried on Transgenic Constructs Show
Allele of O-fut2 Class Mutagen Stocks Known lesion O-fut2GD6370 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes O-fut2HMS02552 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes O-fut2BiP.MtnA.T:Saur\A in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes O-fut2dsRNA.cLa in vitro construct - RNAi 0 Yes O-fut2E442A.E443A.MtnA.T:Saur\A in vitro construct - amino acid replacement 0 Yes O-fut2KK107980 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes O-fut2MtnA.T:Ivir\HA1 in vitro construct - regulatory fusion in vitro construct - coding region fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(1)Exel6227 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD6370} NA P{KK107980} NA P{TRiP.HMS02552} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{RB}O-fut2e01659 NA
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 3 terms )
Molecular Function
CV term Evidence References
peptide-O-fucosyltransferase activity inferred from direct assay (assigned by UniProtKB) (Luo et al., 2006)
Biological Process
CV term Evidence References
O-glycan processing inferred from direct assay (assigned by UniProtKB) (Luo et al., 2006)
Cellular Component
CV term Evidence References
endoplasmic reticulum inferred from direct assay (assigned by UniProtKB) (Luo et al., 2006)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
fucosyltransferase activity inferred from sequence or structural similarity with UniProtKB:Q9Y2G5 (assigned by UniProtKB) (Roos et al., 2002)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	gene_with_edited_transcript (Graveley et al., 2011) nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
O-fut2 - Crc anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) O-fut2 - Fer1HCH anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) O-fut2 - Grp anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) O-fut2 - Pdi experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) O-fut2 - hyd anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions O-fut2 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0027791 DroID - A comprehensive database of gene and protein interactions. • FBgn0027791
Orthologs
OrthoDB Orthologs (39) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG66Q7C8 Dipteran inclusive ortholog search EOG6Q2DPX Insect inclusive ortholog search EOG6X96CT Arthropod inclusive ortholog search EOG6BRV29 Metazoa inclusive ortholog search EOG6JDW1H
Orthologs in Drosophila Species (EOG66Q7C8)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\O-fut2     Drosophila simulans   Dsim\GD24636 Y   Drosophila sechellia   Dsec\GM18972 Y   Drosophila erecta   Dere\GG12697 Y   Drosophila yakuba   Dyak\O-fut2 Y   Drosophila ananassae   Dana\GF21276 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA13247 Y   Drosophila persimilis   Dper\GL14377 Y   Drosophila willistoni   Dwil\GK25021 Y   Drosophila virilis   Dvir\GJ19195 Y   Drosophila mojavensis   Dmoj\GI15662 Y   Drosophila grimshawi   Dgri\GH11874 Y
Orthologs in non-Drosophila Dipterans (EOG6Q2DPX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL004163   Anopheles gambiae Malaria mosquito  Agam\AGAP000757   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ010627
Orthologs in non-Dipteran Insects (EOG6X96CT)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\O-fut2   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG035349   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG037273   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH22194   Atta cephalotes Leafcutter ant  Acep\ACEP13635   Camponotus floridanus Florida carpenter ant  Cflo\CFLO20712   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL17765   Linepithema humile Argentine ant  Lhum\LH20476   Pogonomyrmex barbatus Red harvester ant  Pbar\PB20348   Acyrthosiphon pisum Pea aphid  Apim\ACYPI004711   Bombyx mori Silkmoth  Bmor\pofut2   Pediculus humanus Human body louse  Phum\PHUM129460   Tribolium castaneum Red flour beetle  Tcas\TC030583
Orthologs in non-Insect Arthropods (EOG6BRV29)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_323127   Ixodes scapularis Deer tick  Isca\ISCW024525   Ixodes scapularis Deer tick  Isca\ISCW022327   Ixodes scapularis Deer tick  Isca\ISCW024752
Orthologs in non-Arthropod Metazoa (EOG6JDW1H)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\pad-2   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_008163gn   Danio rerio Zebrafish  Drer\pofut2   Xenopus tropicalis Western clawed frog  Xtro\pofut2   Mus musculus House mouse  Mmus\Pofut2   Rattus norvegicus Norway rat  Rnor\Pofut2   Homo sapiens Human  Hsap\ENSG00000186866
Human Orthologs (1)
Gene OMIM HGNC Hsap\ENSG00000186866
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD24636 Drosophila sechellia Dsec\GM18972 Drosophila erecta Dere\GG12697 Drosophila yakuba Dyak\O-fut2 Drosophila ananassae Dana\GF21276 Drosophila pseudoobscura pseudoobscura Dpse\GA13247 Drosophila persimilis Dper\GL14377 Drosophila willistoni Dwil\GK25021 Drosophila virilis Dvir\GJ19195 Drosophila mojavensis Dmoj\GI15662 Drosophila grimshawi Dgri\GH11874
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	28805 O-fut25.2c w* 17976 PBac{RB}O-fut2e01659 w1118 42860 y1 sc* v1; P{TRiP.HMS02552}attP40
Harvard	- PBac{RB}O-fut2e01659
VDRC	v41361 w1118; P{GD6370}v41361 v41362 w1118; P{GD6370}v41362
Genomic Clones ( 1 )
	BACR09H15 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 14 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH07929
Other clones	DPiM_GH07929
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH24864 GM05333 LP11119 RE23962 SD20990 SD27266
Other clones	Dmel_dig_009398_0652_2999 Dmel_dig_011422_0602_0708 IP05689 IP05789 IP05889 IP05989
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0027791 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31098
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: O-fut2 EG:BACN32G11.6 (Roos et al., 2002)
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_130560 RefSeq (Proteins) • NP_569916 DDBJ / EMBL / GenBank • AAF45629 AAK77300 AI108705 AI402112 AL035632 AY047568 CAB53644 Entrez Gene - A searchable database of RefSeq genes. • 31098 UniProtKB/Swiss-Prot • Q9W589
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • GDP-fucose protein O-fucosyltransferase (IPR019378)
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0027791 DroID - A comprehensive database of gene and protein interactions. • FBgn0027791 DRSC - Results from RNAi screens. • FBgn0027791 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0027791 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14789-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0027791 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31098 modMine - Data generated by the modENCODE project. • FBgn0027791
Synonyms & Secondary IDs ( 7 )
Reported As
Symbol Synonym	CG14789 (Roos et al., 2002, Benos, 2000.12.13, Luo et al., 2006, Keleman et al., 2009.8.5, Ni et al., 2010.12.1) EG:BACN32G11.6 (Benos et al., 2001, ) O-fut (Giagtzoglou et al., 2007) O-FUT2 (Roos et al., 2002) O-fut2 (Kaplan et al., 2008, Irvine, 2009.9.25) Ofut2 (Luo et al., 2006)
Name Synonym	O-fucosyltransferase 2 (Roos et al., 2002, Luo et al., 2006)
Secondary FlyBase IDs
References ( 21 )
Generate a list of	All references relating to this gene ( 21 )
List References by type	Research paper  ( 3 ) Supplementary material  ( 5 ) Review  ( 1 ) Personal communication to FlyBase  ( 10 ) Abstract  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...