DDP1, Vigilin
Please see the JBrowse view of Dmel\Dp1 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Gene model reviewed during 5.50
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.55
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Dp1 using the Feature Mapper tool.
Comment: maternally deposited
Dp1 protein binds dodeca-satellite DNA sequences with high affinity. Dp1 localizes to the heterochromatic chromocenter. It also localizes to euchromatic sites on all chromosomes, colocalizing with Su(var)205 protein.
GBrowse - Visual display of RNA-Seq signals
View Dmel\Dp1 in GBrowse 2Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Source for merge of: Dp1 BcDNA:LD21677
Source for merge of: Dp1 anon-WO0118547.516 anon-WO0172774.168
Source for merge of: Dp1 BcDNA:LD21383
Dp1 complements a Scer\SCP160 deletion in yeast, a multi KH domain protein that is involved in control of cell ploidy.
Source for merge of Dp1 BcDNA:LD21677 was sequence comparison ( date:000202 ).
Source for merge of Dp1 anon-WO0118547.516 anon-WO0172774.168 was sequence comparison ( date:051113 ).
Source for merge of Dp1 BcDNA:LD21383 was sequence comparison ( date:000202 ).
Dp1 encodes a single stranded DNA-binding protein that binds the unstructured dodeca-satellite C-strand in pericentric heterochromatin with high affinity and specificity.