kirre expression begins at embryonic stage 11, in the visceral muscle pregenitors. During stages 12-13, kirre transcript is expressed in segmentally repeated clusters, in the muscle founder cells. During stages 13-14 expression continues in outgrowing muscle founder cells, and in muscle precursors. Expression can be last detected at embryonic stage 16, in a ventral U-shaped pattern at the posterior end of the head region.

(Strunkelnberg et al., 2001)

kirre transcript is expressed in all somatic muscle precursors. By the end of embryonic stage 12, kirre expression is downregulated in the adult muscle precursor cells.

(Ruiz-Gomez et al., 2000)

At 18-22 hours SPF, kirre protein can be found in the myotubes of developing dorsal medial flight muscles, but not in swarming myoblasts. It resides mainly on the membrane of myotubes, as well as in fusing puncta. kirre protein is enriched at contact points of fusing myoblasts.

(Gildor et al., 2012)

kirre protein expression is specific to muscle founder cells.

(Jin et al., 2011)

kirre protein is observed primarily in interommatidial cells.

(Bao et al., 2010)

kirre is expressed in garland cells (starting in mid-embryongenesis) and in pericardial cells (starting in the first instar larva) through adulthood. It is co-expressed with sns.

(Weavers et al., 2009)

kirre protein is localized to regions of cell-cell contact in mononucleate embryonic garland cells and binucleate embryonic/larval garland cells; distribution is also observed in in intracellular and cell surface puncta. sns protein is partially colocalized with kirre protein. kirre protein is expressed in garland cells at all larval stages; immuno-EM reveals kirre protein to be localized to the nephrocyte diaphragm of larval garland cells in third instar larvae.

(Zhuang et al., 2009)