Gene model reviewed during 5.39
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.45
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\chm using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\chm in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
chm and Rpd3 act as antagonistic cofactors of Jra and kay proteins to modulate JNK-dependent transcription during thorax metamorphosis and JNK-induced apoptosis. chm enhances JNK signaling during thorax closure during metamorphosis and acts positively in the JNK-dependent apoptotic pathway.
dsRNA has been made from templates generated with primers directed against this gene. RNAi of chm causes an increase in the number of class I da neurons. RNAi also causes alterations in the number of MD neurons and defects in dendrite morphogenesis.