DmKAP, Kap, kinesin-2
the non-motor accessory subunit of Kinesin II - involved in intraflagellar transport - required for the axoneme growth and maintenance of the cilia in Drosophila type I sensory neurons - expressed in Johnston's organ and required for hearing
Gene model reviewed during 5.42
Gene model reviewed during 5.43
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Gene model reviewed during 5.51
None of the polypeptides share 100% sequence identity.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Kap3 using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Kap3 in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Kap3 is required for the assembly of sensory cilia but not for the assembly of the sperm flagellum.
Identification: strong sequence similarity to SpKAP115.
Point mutants show an uncoordinated mutant phenotype as adults. Additionally, odor perception may be affected.