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Gene Dmel\CG17841

General Information
Symbol	Dmel\CG17841	Species	D. melanogaster
Name		Annotation symbol	CG17841
Feature type	protein_coding_gene	FlyBase ID	FBgn0028480
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	9B12-9B14	Sequence location	X:10,262,084..10,277,264 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG17841 (FBgn0028480). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 8 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: TRAM/LAG1/CLN8 homology domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 12-24 hour embryonic stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, adult midgut, adult hindgut, adult heart, adult fat body, adult salivary gland, adult spermathecae, adult male accessory gland, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval midgut, larval hindgut, larval/adult Malpighian tubules, larval fat body, larval salivary gland, larval trachea, adult ovary, larval carcass. Comments on Affy2 ProbeSet: ProbeSet 1623704_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG17841. Gene sequence location is X:10262084..10277264.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN22774 HFA17737
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 9B12-9B14   Limits computationally determined from genome sequence between P{EP}l(1)G0289EP379 and P{EP}PPP4R2rEP307
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG17841 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG17841-RA FBtr0071444  NM_132394   2140   429
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG17841-PA   FBpp0071379   47.8   429   9.95     NP_572622   AAF46579
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • TRAM/LAG1/CLN8 homology domain (IPR006634)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA263917   AA390759   AA440958   AA539705   AA540231   AA540482   AA695020   AA698322   AA698718   AA801785   AA802804   AA803986   AA949614   AA952097   AE014298 AAF46579   AF181646 AAD55432   AI063371   AI063543   AI107019   AI124299   AI134779   AI238042   AI238111   AI293028   AI293476   AI386769   AI387158   AI388820   AI389987   AI402285   AI405748   AI456252   AI516513   AI517071   AI518487   AI542169   BF485976   BF495128   BF497506   BF503419   BF505216   BG631918   BG634321   BG640628   BH759523   BI165683   BI172381   BI213262   BI213498   BI215844   BI233113   BI352550   BI365191   BI371652   BI372960   BI567441   BI570913   BI572415   BI577363   BI591890   BI591896   BI610689   BI612618   BI612822   BI625021   BI626000   BI631075   BI631315   BI638305   BI638830   BI641213   CA804674   CK131898   CK659191   CL705765   CO196655   CO262283   CO264775   CO264949   CO265184   CO269729   CO269989   CO271791   CO290419   CO295814   CO296626   CO298524   CO304673   CO307661   CO317892   CO323334   CO331108   CO333467   CZ471571   EC052886   EC059792   EC064093   EC070538   EC072811   EC194368   EC198870   EC201289   EC204222   EC208177   EC220077   EC221311   EC226108   EC227104   EC231232   EC234620   EC236263   EC236277   EC239567   EC242264   EC242446   EC243510   EC246542   EC251262
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9V3S7
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0028480    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0028480 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderate expression. Peak expression observed within 12-24 hour embryonic stages, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0028480 expression level Developmental Stage   Expression Level embryo 00-02hr    6162 embryo 02-04hr    4969 embryo 04-06hr    4152 embryo 06-08hr    3776 embryo 08-10hr    3504 embryo 10-12hr    3188 embryo 12-14hr    2689 embryo 14-16hr    6554 embryo 16-18hr    10300 embryo 18-20hr    14294 embryo 20-22hr    7173 embryo 22-24hr    7439 larva L1    5991 larva L2    6720 larva L3 12hr old    5425 larva L3 puffstage 1-2    1759 larva L3 puffstage 3-6    1815 larva L3 puffstage 7-9    1216 white prepupae new    1377 white prepupae 12hr    1872 white prepupae 24hr    1485 pupae 2d postWPP    1920 pupae 3d postWPP    3411 pupae 4d postWPP    7913 adult male 01day    8672 adult male 05day    10111 adult male 30day    10103 adult female 01day    9447 adult female 05day    6274 adult female 30day    6721 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (6162) embryo 02-04hr  (4969) embryo 04-06hr  (4152) embryo 06-08hr  (3776) embryo 08-10hr  (3504) embryo 10-12hr  (3188) embryo 12-14hr  (2689) embryo 14-16hr  (6554) embryo 16-18hr  (10300) embryo 18-20hr  (14294) embryo 20-22hr  (7173) embryo 22-24hr  (7439) larva L1  (5991) larva L2  (6720) larva L3 12hr old  (5425) larva L3 puffstage 1-2  (1759) larva L3 puffstage 3-6  (1815) larva L3 puffstage 7-9  (1216) white prepupae new  (1377) white prepupae 12hr  (1872) white prepupae 24hr  (1485) pupae 2d postWPP  (1920) pupae 3d postWPP  (3411) pupae 4d postWPP  (7913) adult male 01day  (8672) adult male 05day  (10111) adult male 30day  (10103) adult female 01day  (9447) adult female 05day  (6274) adult female 30day  (6721) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (6162) embryo 02-04hr  (4969) embryo 04-06hr  (4152) embryo 06-08hr  (3776) embryo 08-10hr  (3504) embryo 10-12hr  (3188) embryo 12-14hr  (2689) embryo 14-16hr  (6554) embryo 16-18hr  (10300) embryo 18-20hr  (14294) embryo 20-22hr  (7173) embryo 22-24hr  (7439) larva L1  (5991) larva L2  (6720) larva L3 12hr old  (5425) larva L3 puffstage 1-2  (1759) larva L3 puffstage 3-6  (1815) larva L3 puffstage 7-9    1216 white prepupae new    1377 white prepupae 12hr  (1872) white prepupae 24hr  1485 pupae 2d postWPP  (1920) pupae 3d postWPP  (3411) pupae 4d postWPP  (7913) adult male 01day  (8672) adult male 05day  (10111) adult male 30day  (10103) adult female 01day  (9447) adult female 05day  (6274) adult female 30day  (6721) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    6162 embryo 02-04hr    4969 embryo 04-06hr    4152 embryo 06-08hr    3776 embryo 08-10hr    3504 embryo 10-12hr    3188 embryo 12-14hr    2689 embryo 14-16hr    6554 embryo 16-18hr  10300 embryo 18-20hr  (14294) embryo 20-22hr    7173 embryo 22-24hr    7439 larva L1    5991 larva L2    6720 larva L3 12hr old    5425 larva L3 puffstage 1-2    1759 larva L3 puffstage 3-6    1815 larva L3 puffstage 7-9    1216 white prepupae new    1377 white prepupae 12hr    1872 white prepupae 24hr    1485 pupae 2d postWPP    1920 pupae 3d postWPP    3411 pupae 4d postWPP    7913 adult male 01day    8672 adult male 05day  10111 adult male 30day  10103 adult female 01day    9447 adult female 05day    6274 adult female 30day    6721 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    6162 embryo 02-04hr    4969 embryo 04-06hr    4152 embryo 06-08hr    3776 embryo 08-10hr    3504 embryo 10-12hr    3188 embryo 12-14hr    2689 embryo 14-16hr    6554 embryo 16-18hr    10300 embryo 18-20hr    14294 embryo 20-22hr    7173 embryo 22-24hr    7439 larva L1    5991 larva L2    6720 larva L3 12hr old    5425 larva L3 puffstage 1-2    1759 larva L3 puffstage 3-6    1815 larva L3 puffstage 7-9    1216 white prepupae new    1377 white prepupae 12hr    1872 white prepupae 24hr    1485 pupae 2d postWPP    1920 pupae 3d postWPP    3411 pupae 4d postWPP    7913 adult male 01day    8672 adult male 05day    10111 adult male 30day    10103 adult female 01day    9447 adult female 05day    6274 adult female 30day    6721 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0028480 expression level Developmental Stage   Expression Level embryo 00-02hr    6162 embryo 02-04hr    4969 embryo 04-06hr    4152 embryo 06-08hr    3776 embryo 08-10hr    3504 embryo 10-12hr    3188 embryo 12-14hr    2689 embryo 14-16hr    6554 embryo 16-18hr    10300 embryo 18-20hr    14294 embryo 20-22hr    7173 embryo 22-24hr    7439 larva L1    5991 larva L2    6720 larva L3 12hr old    5425 larva L3 puffstage 1-2    1759 larva L3 puffstage 3-6    1815 larva L3 puffstage 7-9    1216 white prepupae new    1377 white prepupae 12hr    1872 white prepupae 24hr    1485 pupae 2d postWPP    1920 pupae 3d postWPP    3411 pupae 4d postWPP    7913 adult male 01day    8672 adult male 05day    10111 adult male 30day    10103 adult female 01day    9447 adult female 05day    6274 adult female 30day    6721 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (6162) embryo 02-04hr  (4969) embryo 04-06hr  (4152) embryo 06-08hr  (3776) embryo 08-10hr  (3504) embryo 10-12hr  (3188) embryo 12-14hr  (2689) embryo 14-16hr  (6554) embryo 16-18hr  (10300) embryo 18-20hr  (14294) embryo 20-22hr  (7173) embryo 22-24hr  (7439) larva L1  (5991) larva L2  (6720) larva L3 12hr old  (5425) larva L3 puffstage 1-2  (1759) larva L3 puffstage 3-6  (1815) larva L3 puffstage 7-9  (1216) white prepupae new  (1377) white prepupae 12hr  (1872) white prepupae 24hr  (1485) pupae 2d postWPP  (1920) pupae 3d postWPP  (3411) pupae 4d postWPP  (7913) adult male 01day  (8672) adult male 05day  (10111) adult male 30day  (10103) adult female 01day  (9447) adult female 05day  (6274) adult female 30day  (6721) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (6162) embryo 02-04hr  (4969) embryo 04-06hr  (4152) embryo 06-08hr  (3776) embryo 08-10hr  (3504) embryo 10-12hr  (3188) embryo 12-14hr  (2689) embryo 14-16hr  (6554) embryo 16-18hr  (10300) embryo 18-20hr  (14294) embryo 20-22hr  (7173) embryo 22-24hr  (7439) larva L1  (5991) larva L2  (6720) larva L3 12hr old  (5425) larva L3 puffstage 1-2  1759 larva L3 puffstage 3-6  1815 larva L3 puffstage 7-9    1216 white prepupae new    1377 white prepupae 12hr  1872 white prepupae 24hr  1485 pupae 2d postWPP  1920 pupae 3d postWPP  (3411) pupae 4d postWPP  (7913) adult male 01day  (8672) adult male 05day  (10111) adult male 30day  (10103) adult female 01day  (9447) adult female 05day  (6274) adult female 30day  (6721) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    6162 embryo 02-04hr    4969 embryo 04-06hr    4152 embryo 06-08hr    3776 embryo 08-10hr    3504 embryo 10-12hr    3188 embryo 12-14hr    2689 embryo 14-16hr    6554 embryo 16-18hr  10300 embryo 18-20hr  14294 embryo 20-22hr    7173 embryo 22-24hr    7439 larva L1    5991 larva L2    6720 larva L3 12hr old    5425 larva L3 puffstage 1-2    1759 larva L3 puffstage 3-6    1815 larva L3 puffstage 7-9    1216 white prepupae new    1377 white prepupae 12hr    1872 white prepupae 24hr    1485 pupae 2d postWPP    1920 pupae 3d postWPP    3411 pupae 4d postWPP    7913 adult male 01day    8672 adult male 05day  10111 adult male 30day  10103 adult female 01day    9447 adult female 05day    6274 adult female 30day    6721 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    6162 embryo 02-04hr    4969 embryo 04-06hr    4152 embryo 06-08hr    3776 embryo 08-10hr    3504 embryo 10-12hr    3188 embryo 12-14hr    2689 embryo 14-16hr    6554 embryo 16-18hr    10300 embryo 18-20hr    14294 embryo 20-22hr    7173 embryo 22-24hr    7439 larva L1    5991 larva L2    6720 larva L3 12hr old    5425 larva L3 puffstage 1-2    1759 larva L3 puffstage 3-6    1815 larva L3 puffstage 7-9    1216 white prepupae new    1377 white prepupae 12hr    1872 white prepupae 24hr    1485 pupae 2d postWPP    1920 pupae 3d postWPP    3411 pupae 4d postWPP    7913 adult male 01day    8672 adult male 05day    10111 adult male 30day    10103 adult female 01day    9447 adult female 05day    6274 adult female 30day    6721 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0028480    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0028480 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, adult midgut, adult hindgut, adult heart, adult fat body, adult salivary gland, adult spermathecae, adult male accessory gland, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval midgut, larval hindgut, larval/adult Malpighian tubules, larval fat body, larval salivary gland, larval trachea, adult ovary, larval carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0028480 expression level Tissue   Expression Level Larval Central Nervous System    227.25 Larval Midgut    165.2 Larval Hindgut    376 Larval Malpighian Tubules    278.3 Larval Fat Body    354.2 Larval Salivary Gland    112.4 Larval Trachea    217.325 Larval Carcass    129.3 Adult Head    1043.6 Adult Eye    784.275 Adult Brain    1011.2 Adult Thoracic-Abdominal Ganglion    1829.5 Adult Crop    1053.7 Adult Midgut    639.5 Adult Hindgut    1076.5 Adult Malpighian Tubules    321.2 Adult Fat Body    2706.2 Adult Salivary Gland    1306.7 Adult Heart    2294.05 Adult VirginFemale Spermatheca    2263.5 Adult InseminatedFemale Spermatheca    2122.3 Adult Ovary    391.9 Adult Testis    96.4 Adult Male Accessory Gland    1517.9 Adult Carcass    1731.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    227.25 Larval Midgut    165.2 Larval Hindgut    376 Larval Malpighian Tubules    278.3 Larval Fat Body    354.2 Larval Salivary Gland    112.4 Larval Trachea    217.325 Larval Carcass    129.3 Adult Head  (1043.6) Adult Eye  (784.275) Adult Brain  (1011.2) Adult Thoracic-Abdominal Ganglion  (1829.5) Adult Crop  (1053.7) Adult Midgut  (639.5) Adult Hindgut  (1076.5) Adult Malpighian Tubules    321.2 Adult Fat Body  (2706.2) Adult Salivary Gland  (1306.7) Adult Heart  (2294.05) Adult VirginFemale Spermatheca  (2263.5) Adult InseminatedFemale Spermatheca  (2122.3) Adult Ovary    391.9 Adult Testis    96.4 Adult Male Accessory Gland  (1517.9) Adult Carcass  (1731.5) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    227.25 Larval Midgut    165.2 Larval Hindgut    376 Larval Malpighian Tubules    278.3 Larval Fat Body    354.2 Larval Salivary Gland    112.4 Larval Trachea    217.325 Larval Carcass    129.3 Adult Head  1043.6 Adult Eye    784.275 Adult Brain  1011.2 Adult Thoracic-Abdominal Ganglion  (1829.5) Adult Crop  1053.7 Adult Midgut    639.5 Adult Hindgut  1076.5 Adult Malpighian Tubules    321.2 Adult Fat Body  (2706.2) Adult Salivary Gland  (1306.7) Adult Heart  (2294.05) Adult VirginFemale Spermatheca  (2263.5) Adult InseminatedFemale Spermatheca  (2122.3) Adult Ovary    391.9 Adult Testis    96.4 Adult Male Accessory Gland  (1517.9) Adult Carcass  (1731.5) Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    227.25 Larval Midgut    165.2 Larval Hindgut    376 Larval Malpighian Tubules    278.3 Larval Fat Body    354.2 Larval Salivary Gland    112.4 Larval Trachea    217.325 Larval Carcass    129.3 Adult Head    1043.6 Adult Eye    784.275 Adult Brain    1011.2 Adult Thoracic-Abdominal Ganglion    1829.5 Adult Crop    1053.7 Adult Midgut    639.5 Adult Hindgut    1076.5 Adult Malpighian Tubules    321.2 Adult Fat Body    2706.2 Adult Salivary Gland    1306.7 Adult Heart    2294.05 Adult VirginFemale Spermatheca    2263.5 Adult InseminatedFemale Spermatheca    2122.3 Adult Ovary    391.9 Adult Testis    96.4 Adult Male Accessory Gland    1517.9 Adult Carcass    1731.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0028480 expression level Tissue   Expression Level Larval Central Nervous System    227.25 Larval Midgut    165.2 Larval Hindgut    376 Larval Malpighian Tubules    278.3 Larval Fat Body    354.2 Larval Salivary Gland    112.4 Larval Trachea    217.325 Larval Carcass    129.3 Adult Head    1043.6 Adult Eye    784.275 Adult Brain    1011.2 Adult Thoracic-Abdominal Ganglion    1829.5 Adult Crop    1053.7 Adult Midgut    639.5 Adult Hindgut    1076.5 Adult Malpighian Tubules    321.2 Adult Fat Body    2706.2 Adult Salivary Gland    1306.7 Adult Heart    2294.05 Adult VirginFemale Spermatheca    2263.5 Adult InseminatedFemale Spermatheca    2122.3 Adult Ovary    391.9 Adult Testis    96.4 Adult Male Accessory Gland    1517.9 Adult Carcass    1731.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    227.25 Larval Midgut    165.2 Larval Hindgut    376 Larval Malpighian Tubules    278.3 Larval Fat Body    354.2 Larval Salivary Gland    112.4 Larval Trachea    217.325 Larval Carcass    129.3 Adult Head  (1043.6) Adult Eye  784.275 Adult Brain  (1011.2) Adult Thoracic-Abdominal Ganglion  (1829.5) Adult Crop  (1053.7) Adult Midgut  639.5 Adult Hindgut  (1076.5) Adult Malpighian Tubules    321.2 Adult Fat Body  (2706.2) Adult Salivary Gland  (1306.7) Adult Heart  (2294.05) Adult VirginFemale Spermatheca  (2263.5) Adult InseminatedFemale Spermatheca  (2122.3) Adult Ovary    391.9 Adult Testis    96.4 Adult Male Accessory Gland  (1517.9) Adult Carcass  (1731.5) Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    227.25 Larval Midgut    165.2 Larval Hindgut    376 Larval Malpighian Tubules    278.3 Larval Fat Body    354.2 Larval Salivary Gland    112.4 Larval Trachea    217.325 Larval Carcass    129.3 Adult Head  1043.6 Adult Eye    784.275 Adult Brain  1011.2 Adult Thoracic-Abdominal Ganglion  (1829.5) Adult Crop  1053.7 Adult Midgut    639.5 Adult Hindgut  1076.5 Adult Malpighian Tubules    321.2 Adult Fat Body  (2706.2) Adult Salivary Gland  1306.7 Adult Heart  (2294.05) Adult VirginFemale Spermatheca  (2263.5) Adult InseminatedFemale Spermatheca  (2122.3) Adult Ovary    391.9 Adult Testis    96.4 Adult Male Accessory Gland  1517.9 Adult Carcass  (1731.5) Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    227.25 Larval Midgut    165.2 Larval Hindgut    376 Larval Malpighian Tubules    278.3 Larval Fat Body    354.2 Larval Salivary Gland    112.4 Larval Trachea    217.325 Larval Carcass    129.3 Adult Head    1043.6 Adult Eye    784.275 Adult Brain    1011.2 Adult Thoracic-Abdominal Ganglion    1829.5 Adult Crop    1053.7 Adult Midgut    639.5 Adult Hindgut    1076.5 Adult Malpighian Tubules    321.2 Adult Fat Body    2706.2 Adult Salivary Gland    1306.7 Adult Heart    2294.05 Adult VirginFemale Spermatheca    2263.5 Adult InseminatedFemale Spermatheca    2122.3 Adult Ovary    391.9 Adult Testis    96.4 Adult Male Accessory Gland    1517.9 Adult Carcass    1731.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    1043.6   NA  Eye    784.275   NA  Brain    1011.2   227.25  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    1829.5   NA  Crop    1053.7   165.2  Midgut    639.5   376  Hindgut    1076.5   278.3  Malpighian Tubules    321.2   354.2  Fat Body    2706.2   112.4  Salivary Gland    1306.7   NA  Heart    2294.05   217.325  Trachea    NA   NA  VirginFemale Spermatheca    2263.5   NA  InseminatedFemale Spermatheca    2122.3   NA  Ovary    391.9   NA  Testis    96.4   NA  Male Accessory Gland    1517.9   129.3  Carcass    1731.5 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_20
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0028480 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17841-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG17841 Stages(s) 1-3 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage, with Scer\GAL4pnr-MD237 CG17841GD3301 lethal | recessive CG17841PL94 viable CG17841EY01720 Sterility Allele fertile CG17841EY01720 Phenotype manifest in Allele
Classical Alleles ( 5 )
For All Classical Alleles Show
Allele of CG17841 Class Mutagen Stocks Known lesion CG17841EY01720 P-element activity 1 -- CG17841KG04748 P-element activity 1 -- CG17841d00394 P-element activity 0 -- CG17841GG01064 0 -- CG17841PL94 Delta2-3 0 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG17841 Class Mutagen Stocks Known lesion CG17841GD3301 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG17841HMS00305 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG17841KK102573 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD3301} NA P{KK102573} NA P{TRiP.HMS00305} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EPgy2}CG17841EY01720 NA P{Mae-UAS.6.11}CG17841GG01064 NA P{XP}CG17841d00394 NA miscellaneous insertions P{SUPor-P}CG17841KG04748 NA insertion of enhancer trap P{lacW}CG17841PL94 No
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR006634 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG17841 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 58397 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0028480 DroID - A comprehensive database of gene and protein interactions. • FBgn0028480 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31965
Orthologs
Genome-wide drosophilid orthologs	Dana\GF19335 Dere\GG18353 Dgri\GH12015 Dmoj\GI15195 Dper\GL26846 Dpse\GA14695 Dsec\GM11420 Dsim\GD16974 Dvir\GJ14802 Dwil\GK10357 Dyak\GE17842
Curated drosophilid orthologs	Dpse\GA14695
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL000191-PA Aedes aegypti (mosquito) 243824 Branchiostoma floridae (lancelet) BGIBMGA012776-PA Bombyx mori (silk worm) ENSBTAP00000006632 Bos taurus (bovine) ENSCAFP00000028226 Canis familiaris (dog) CPIJ000690 Culex pipens (mosquito) ENSCPOP00000003806 Cavia porcellus (guinea pig) 90753 Capitella spl (polychaete worm) DDB0232172 Dictyostelium discoideum (amoeba) ENSDARP00000031019 Danio rerio (zebra fish) ENSECAP00000021321 Equus caballus (horse) ENSGACP00000007075 Gymnopilus aculeatus (mushroom) ENSGALP00000007691 Gallus gallus (chicken) ENSP00000312017 Homo sapiens (human) 232056 Lottia gigantea (owl limpet) 23177 Monocosta brevicollis (choanoflagellate) ENSMODP00000019594 Monodelphis domestica (gray opossum) ENSMMUP00000016058 Macaca mulatta (rhesus monkey) ENSMUSP00000095640 Mus musculus (house mouse) ENSOANP00000002426 Ornithorynchus anatinus (platypus) ENSORLP00000012385 Oryzias latipes (japanese killifish) PHUM003936-PA Pediculus humanus (human body louse) ENSPPYP00000008192 Pongo pygmaeus (orangutan) ENSPTRP00000053207 Pan troglodytes (chimpanzee) ENSRNOP00000026955 Rattus norvegicus (norway rat) XP_001180491.1 Strongylocentrotus purpuratus (purple sea urchin) XP_001196845.1 Strongylocentrotus purpuratus (purple sea urchin) 32398 Trichoplax adhaerens (metazoa) XP_966650.1 Tribolium castaneum (red flour beetle) ENSTNIP00000005802 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000026919 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000048626 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0235283 FBgn0212372 FBgn0202006 FBgn0188552 FBgn0166363 FBgn0074722 FBgn0164427 FBgn0137944 FBgn0119494 FBgn0110569 FBgn0096345 CPIJ000690 BGIBMGA012776 AGAP011200 AAEL000191 PHUM448920 GLEAN_15440
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	13848 y1 P{SUPor-P}CG17841KG04748 19817 y1 w67c23 P{EPgy2}CG17841EY01720 34948 y1 sc* v1; P{TRiP.HMS00305}attP2
VDRC	v103772 P{KK102573}VIE-260B v5530 w1118; P{GD3301}v5530
Genomic Clones ( 1 )
	BACR29G02 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 111 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH12326
Other clones	DPiM_GH12326
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT03967 AT07396 AT11686 AT19405 AT20087 AT26709 AT30487 GH03131 GH03415 GH06303 GH14026 GH14108 GH16096 GH16977 GH17607 GH19843 GH21426 GH25869 GH27703 GM01952 GM06341 GM12460 GM13006 GM19758 HL04275 HL05542 LD07154 LD08850 LD12775 LD18009 LD19647 LD19981 LD29152 LD29572 LD36141 LD38020 LD42406 LP06633 LP12961 LP16778 RE05624 RE14843 RE18911 RE22589 RE29393 RE50430 RE58580 RE60161 RE71029 RH05703 RH07924 RH08606 RH08618 RH16271 RH37835 RH41551 RH41805 RH60480 RH60868 RH64808 RH66523 SD08302 SD11754 SD20558 SD21221 SD24430
Other clones	30718 32260 32500 57187 63467 74021 78164 81293 81494 122613 165183 165441 194729 281791 AI124299 CK01.2C.H3 CK01.95A.A4 CK01.100C.H7 CK01.104C.G4 CK01.126C.E8 CK01.129B.D1 CK01.170C.B6 EC052886 EK007123 EK073926 EK084932 EK095713 EK097052 EK104630 EK140314 EK141020 EK141759 EK173164 EK190232 EK211641 EK214459 EK245523 EK255206 EK269636 EK298035 EK307016 ESG0114d.B21_A08 RE18627
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0028480 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31965
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG17841 anon-EST:Liang-2.12 (Ashburner, 2004.6.30)
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132394 RefSeq (Proteins) • NP_572622 DDBJ / EMBL / GenBank • AAD55432 AAF46579 AF181646 AI124299 AI134779 AI402285 BH759523 CL705765 CZ471571 Entrez Gene - A searchable database of RefSeq genes. • 31965 UniProtKB/TrEMBL • Q9V3S7
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • TRAM/LAG1/CLN8 homology domain (IPR006634)
Linkouts
	BioGRID - A database of protein and genetic interactions • 58397 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0028480 DroID - A comprehensive database of gene and protein interactions. • FBgn0028480 DRSC - Results from RNAi screens. • FBgn0028480 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0028480 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG17841-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0028480 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31965 InParanoid A subset of ortholog calls from InParanoid. • AAEL000191-PA Aedes aegypti (mosquito) 243824 Branchiostoma floridae (lancelet) BGIBMGA012776-PA Bombyx mori (silk worm) ENSBTAP00000006632 Bos taurus (bovine) ENSCAFP00000028226 Canis familiaris (dog) CPIJ000690 Culex pipens (mosquito) ENSCPOP00000003806 Cavia porcellus (guinea pig) 90753 Capitella spl (polychaete worm) DDB0232172 Dictyostelium discoideum (amoeba) ENSDARP00000031019 Danio rerio (zebra fish) ENSECAP00000021321 Equus caballus (horse) ENSGACP00000007075 Gymnopilus aculeatus (mushroom) ENSGALP00000007691 Gallus gallus (chicken) ENSP00000312017 Homo sapiens (human) 232056 Lottia gigantea (owl limpet) 23177 Monocosta brevicollis (choanoflagellate) ENSMODP00000019594 Monodelphis domestica (gray opossum) ENSMMUP00000016058 Macaca mulatta (rhesus monkey) ENSMUSP00000095640 Mus musculus (house mouse) ENSOANP00000002426 Ornithorynchus anatinus (platypus) ENSORLP00000012385 Oryzias latipes (japanese killifish) PHUM003936-PA Pediculus humanus (human body louse) ENSPPYP00000008192 Pongo pygmaeus (orangutan) ENSPTRP00000053207 Pan troglodytes (chimpanzee) ENSRNOP00000026955 Rattus norvegicus (norway rat) XP_001180491.1 Strongylocentrotus purpuratus (purple sea urchin) XP_001196845.1 Strongylocentrotus purpuratus (purple sea urchin) 32398 Trichoplax adhaerens (metazoa) XP_966650.1 Tribolium castaneum (red flour beetle) ENSTNIP00000005802 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000026919 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000048626 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31965 modMine - Data generated by the modENCODE project. • FBgn0028480 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0235283 FBgn0212372 FBgn0202006 FBgn0188552 FBgn0166363 FBgn0074722 FBgn0164427 FBgn0137944 FBgn0119494 FBgn0110569 FBgn0096345 CPIJ000690 BGIBMGA012776 AGAP011200 AAEL000191 PHUM448920 GLEAN_15440
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	anon-EST:Liang-2.12   BcDNA:GH12326 (Giot et al., 2003, ) CG17841 (White et al., 2011, Keleman et al., 2009.8.5, Ni et al., 2011.7.19) clone 2.12 (Liang and Biggin, 1998)
Name Synonym
Secondary FlyBase IDs
	FBgn0025969
References ( 16 )
Research paper	White et al., 2011, J. Cell Biol. 193(4): 677--694 Drosophila histone locus bodies form by hierarchical recruitment of components. [FBrf0213662] Bourbon et al., 2002, Mech. Dev. 110(1-2): 71--83 A P-insertion screen identifying novel X-linked essential genes in Drosophila. [FBrf0141645] Liang and Biggin, 1998, Development 125(22): 4471--4482 Eve and ftz regulate a wide array of genes in blastoderm embryos: the selector homeoproteins directly or indirectly regulate most genes in Drosophila. [FBrf0105875]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Ni et al., 2011.7.19, TRiP germline vector pVALIUM21. TRiP germline vector pVALIUM21. [FBrf0214641] Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Ashburner, 2004.6.30, Liang anon-ESTs. Liang anon-ESTs. [FBrf0178761] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]