FlyBase Gene Report: Dmel\bdl

General Information

Symbol

Dmel\bdl

Species

D. melanogaster

Name

borderless

Annotation Symbol

CG16857

Feature Type

protein_coding_gene

FlyBase ID

FBgn0028482

Gene Model Status

Stock Availability

7 publicly available

Gene Summary

borderless (bdl) encodes a cell adhesion molecule that is required for glial extension and axon ensheathment. Its down-regulation by the products of tutl and Lar is required for photoreceptor axonal tiling and layer-specific target selection. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)

All Summaries

Gene Snapshot
Alliance
Auto summary
UniProtKB
Interactive Fly

Also Known As

BcDNA:GH11322

Key Links

Genomic Location

Cytogenetic map

Sequence location

2L:4,324,554..4,331,830 [+]

Recombination map

2-12

RefSeq locus

NT_033779 REGION:4324554..4331830

Sequence

Get Decorated FASTA

Genomic Maps

JBrowse GBrowse

Other Genome Views

The following external sites may use different assemblies or annotations than FlyBase.

Function

GO Summary Ribbons

Gene Ontology (GO) Annotations (13 terms)

Molecular Function (1 term)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

enables cell-cell adhesion mediator activity

inferred from physical interaction with FLYBASE:tutl; FB:FBgn0010473

(Cameron et al., 2013)

Terms Based on Predictions or Assertions (1 term)

CV Term

Evidence

References

enables cell-cell adhesion mediator activity

inferred from biological aspect of ancestor with PANTHER:PTN001296633

(assigned by GO_Central )

(Gaudet et al., 2011)

Biological Process (9 terms)

Terms Based on Experimental Evidence (7 terms)

CV Term

Evidence

References

involved_in axon ensheathment

inferred from mutant phenotype

(Cameron et al., 2016)

involved_in axonal transport

inferred from mutant phenotype

(Shaw et al., 2019)

involved_in glial cell growth

inferred from mutant phenotype

(Cameron et al., 2016)

involved_in homophilic cell adhesion via plasma membrane adhesion molecules

inferred from mutant phenotype

(Cameron et al., 2013)

involved_in neuron cell-cell adhesion

inferred from mutant phenotype

(Cameron et al., 2013)

involved_in R7 cell development

inferred from mutant phenotype

(Cameron et al., 2013)

inferred from genetic interaction with FLYBASE:tutl; FB:FBgn0010473

(Cameron et al., 2013)

involved_in response to light stimulus

inferred from mutant phenotype

(Shaw et al., 2019)

Terms Based on Predictions or Assertions (3 terms)

CV Term

Evidence

References

involved_in axon guidance

inferred from biological aspect of ancestor with PANTHER:PTN001296633

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in dendrite self-avoidance

inferred from biological aspect of ancestor with PANTHER:PTN001296633

(assigned by GO_Central )

(Gaudet et al., 2011)

involved_in homophilic cell adhesion via plasma membrane adhesion molecules

inferred from biological aspect of ancestor with PANTHER:PTN001296633

(assigned by GO_Central )

(Gaudet et al., 2011)

Cellular Component (3 terms)

Terms Based on Experimental Evidence (1 term)

CV Term

Evidence

References

located_in integral component of plasma membrane

inferred from direct assay

(Cameron et al., 2013)

Terms Based on Predictions or Assertions (2 terms)

CV Term

Evidence

References

is_active_in axon

inferred from biological aspect of ancestor with PANTHER:PTN001296633

(assigned by GO_Central )

(Gaudet et al., 2011)

is_active_in plasma membrane

inferred from biological aspect of ancestor with PANTHER:PTN001296633

(assigned by GO_Central )

(Gaudet et al., 2011)

Gene Group (FlyBase)

Protein Family (UniProt)

Belongs to the immunoglobulin superfamily. (Q9U4G1)

Protein Signatures (InterPro)

Summaries

Gene Snapshot

borderless (bdl) encodes a cell adhesion molecule that is required for glial extension and axon ensheathment. Its down-regulation by the products of tutl and Lar is required for photoreceptor axonal tiling and layer-specific target selection. [Date last reviewed: 2019-03-07]

Protein Function (UniProtKB)

In the developing eye, has a role in axonal targeting of the R7 photoreceptor where it functions together with tutl. Probably mediates homotypic cell adhesion; the effect is inhibited by Lar.

(UniProt, Q9U4G1)

Summary (Interactive Fly)

Interactive Fly

Gene Model and Products

Number of Transcripts

1

Number of Unique Polypeptides

1

Please see the JBrowse view of Dmel\bdl for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)

Isoform displayed:

Pfam protein domains

InterPro name

classification

start

end

Protein Domains (via SMART)

Isoform displayed:

SMART protein domains

InterPro name

classification

start

end

Structure New Section

Protein 3D structure (Predicted by AlphaFold) (AlphaFold entry Q9U4G1)

If you don't see the viewer to the right, refresh your browser.

Model Confidence:

Very high (pLDDT > 90)
Confident (90 > pLDDT > 70)
Low (70 > pLDDT > 50)
Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Comments on Gene Model

Gene model reviewed during 5.47

Sequence Ontology: Class of Gene

protein_coding_gene

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Assoc. CDS (aa)

FBtr0077425

2730

719

Additional Transcript Data and Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank

FBpp0077115

81.2

719

6.27

Polypeptides with Identical Sequences

There is only one protein coding transcript and one polypeptide associated with this gene

Additional Polypeptide Data and Comments

Reported size (kDa)

Comments

External Data

Subunit Structure (UniProtKB)

Interacts with tutl.

(UniProt, Q9U4G1)

Crossreferences

InterPro - A database of protein families, domains and functional sites

Linkouts

Sequences Consistent with the Gene Model

Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\bdl using the Feature Mapper tool.

External Data

Crossreferences

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

CG16857_1

Linkouts

Expression Data

Expression Summary Ribbons

Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.

For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.

Transcript Expression

expression microarray

Stage

Tissue/Position (including subcellular localization)

Reference

(Xu et al., 2004)

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 13 -- 16

dorsal sensory complex proper primordium

Comment: reported as dorsal/lateral sensory complexes

(Fisher et al., 2012)

embryonic dorsal epidermis

(Fisher et al., 2012)

Additional Descriptive Data

Eye-enriched transcripts determined by ratio of expression level in wild-type heads. versus expression level in so heads.

(Xu et al., 2004)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

immunolocalization

Stage

Tissue/Position (including subcellular localization)

Reference

third instar larval stage

embryonic/larval optic stalk

(Cameron et al., 2016)

eye disc | restricted

(Cameron et al., 2016)

lamina | restricted

(Cameron et al., 2016)

embryonic/larval optic stalk surface glial cell

(Cameron et al., 2016)

lamina anlage glial cell

(Cameron et al., 2016)

embryonic/larval wrapping glial cell of the eye disc

(Cameron et al., 2016)

pharate adult stage P8

lamina | restricted

(Cameron et al., 2013)

medulla | restricted

(Cameron et al., 2013)

adult optic lobe | restricted

(Cameron et al., 2013)

adult optic lobe | restricted

(Cameron et al., 2013)

lamina | restricted

(Cameron et al., 2013)

medulla | restricted

(Cameron et al., 2013)

medulla layer M6

(Cameron et al., 2013)

medulla layer M3

(Cameron et al., 2013)

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

• membrane

(Aradska et al., 2015)

western blot

Stage

Tissue/Position (including subcellular localization)

Reference

(Cameron et al., 2013)

Additional Descriptive Data

In third instar larvae, bdl staining visualizes cellular processes from the eye disc through the optic stalk, into the developing lamina. bdl is present in wrapping glia processes, but not in photoreceptor cell axons, in third instar larvae where photoreceptor cell axons begin to project into the optic lobe.

(Cameron et al., 2016)

bdl-protein is detected in part of the pupal and adult medulla, lamina and inner optic lobe. Within the medulla, bdl-protein is found in R7- and R8-axon terminals in medulla layers M3 and M6 as well as in other neuronal processes.

(Cameron et al., 2013)

Marker for

Subcellular Localization

CV Term

Evidence

References

located_in integral component of plasma membrane

inferred from direct assay

(Cameron et al., 2013)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\bdl in GBrowse 2

RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region

View exonic expression by developmental stage for Dmel\bdl

View exonic expression by tissue for Dmel\bdl

Bulk Downloads

RNA-Seq RPKM values for all genes

Reference

See Gelbart and Emmert, 2013 for analysis details and data files for all genes.

Developmental Proteome: Life Cycle

Developmental Proteome: Embryogenesis

External Data and Images

Linkouts

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0028482

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

33635/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0028482

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0028482

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0028482

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

Flygut - An atlas of the Drosophila adult midgut

FBgn0028482

Images

FlyExpress - Embryonic expression images (BDGP data)

Show all FlyExpress processed images for Dmel\bdl

Stages(s) 13-16

Image Based Resources

Alleles, Insertions, Transgenic Constructs, and Aberrations

Classical and Insertion Alleles ( 8 )

For All Classical and Insertion Alleles Show

Other relevant insertions

Transgenic Constructs ( 11 )

For All Alleles Carried on Transgenic Constructs Show

Transgenic constructs containing/affecting coding region of bdl

Transgenic constructs containing regulatory region of bdl

Aberrations (Deficiencies and Duplications) ( 3 )

Inferred from experimentation ( 3 )

Gene partially disrupted in

(Cameron et al., 2013)

Gene disrupted in

(Ryder, 2004.4.26)

(Zhou et al., 2012)

Inferred from location ( 0 )

Alleles Representing Disease-Implicated Variants

Phenotypes

For more details about a specific phenotype click on the relevant allele symbol.

Lethality

Allele

viable, with Dcr-2^UAS.cDa, Scer\GAL4^elav.PLu

bdl^GD2597

viable, with Scer\GAL4^Mef2.PR

viable, with Scer\GAL4^pnr-MD237

Other Phenotypes

Allele

abnormal neuroanatomy, with Scer\GAL4^GMR.PU

bdl^UAS.Tag:FLAG

abnormal neuroanatomy | third instar larval stage

bdl^EX2

abnormal neuroanatomy | third instar larval stage, with Scer\GAL4^Ntan1-Mz97

Phenotype manifest in

Allele

axon, with Scer\GAL4^GMR.PU

bdl^UAS.Tag:FLAG

embryonic/larval optic stalk | third instar larval stage

bdl^EX2

embryonic/larval optic stalk | third instar larval stage, with Scer\GAL4^Ntan1-Mz97

embryonic/larval wrapping glial cell of the eye disc | third instar larval stage

bdl^EX2

embryonic/larval wrapping glial cell of the eye disc | third instar larval stage, with Scer\GAL4^Ntan1-Mz97

rhabdomere R7, with Scer\GAL4^GMR.PU

bdl^UAS.Tag:FLAG

rhabdomere R8, with Scer\GAL4^GMR.PU

bdl^UAS.Tag:FLAG

Orthologs

Downloads

Download All DIOPT Orthologs

Human Orthologs (via DIOPT v8.0)

Homo sapiens (Human) (39)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

6 of 15

Yes

No

2

5 of 15

No

No

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

No

3

1 of 15

No

No

2

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

No

1 of 15

No

No

1 of 15

No

Yes

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

No

1 of 15

No

No

4

1 of 15

No

No

1 of 15

No

No

1

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1

1 of 15

No

Yes

Model Organism Orthologs (via DIOPT v8.0)

Mus musculus (laboratory mouse) (28)

Species\Gene Symbol

Score

Best Score

Best Reverse Score

Source

Alignment

Complementation?

Transgene?

5 of 15

Yes

No

4 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

No

1 of 15

No

No

1

1 of 15

No

No

1

1 of 15

No

No

1

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

Rattus norvegicus (Norway rat) (24)

5 of 13

Yes

No

5 of 13

Yes

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

Yes

1 of 13

No

Yes

1 of 13

No

Yes

1 of 13

No

Yes

1 of 13

No

Yes

1 of 13

No

Yes

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

Rnor\LOC103693683

1 of 13

No

Yes

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

No

1 of 13

No

Yes

1 of 13

No

No

1 of 13

No

Yes

Xenopus tropicalis (Western clawed frog) (20)

5 of 12

Yes

Yes

5 of 12

Yes

Yes

1 of 12

No

No

1 of 12

No

No

1 of 12

No

Yes

1 of 12

No

Yes

1 of 12

No

Yes

1 of 12

No

No

1 of 12

No

Yes

1 of 12

No

No

Xtro\LOC100486104

1 of 12

No

Yes

Xtro\LOC100489139

1 of 12

No

Yes

Xtro\LOC100494136

1 of 12

No

Yes

Xtro\LOC100496351

1 of 12

No

Yes

1 of 12

No

Yes

1 of 12

No

No

1 of 12

No

No

1 of 12

No

No

1 of 12

No

No

1 of 12

No

No

Danio rerio (Zebrafish) (35)

5 of 15

Yes

No

5 of 15

Yes

No

4 of 15

No

No

4 of 15

No

No

2 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

Yes

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

Drer\si:ch211-8c17.3

1 of 15

No

Yes

Drer\si:ch1073-459j12.1

1 of 15

No

No

Drer\si:dkeyp-75h12.2

1 of 15

No

No

1 of 15

No

Yes

Drer\zgc:110372

1 of 15

No

No

Drer\zgc:154125

1 of 15

No

Yes

Caenorhabditis elegans (Nematode, roundworm) (14)

5 of 15

Yes

No

1 of 15

No

Yes

1 of 15

No

No

1 of 15

No

No

1 of 15

No

Yes

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

1 of 15

No

No

Arabidopsis thaliana (thale-cress) (0)

No records found.

Saccharomyces cerevisiae (Brewer's yeast) (0)

No records found.

Schizosaccharomyces pombe (Fission yeast) (0)

No records found.

Other Organism Orthologs (via OrthoDB)

Paralogs

Downloads

Download All DIOPT Paralogs

Paralogs (via DIOPT v8.0)

Drosophila melanogaster (Fruit fly) (55)

Gene Symbol

Score

Source

Alignment

4 of 10

2 of 10

2 of 10

2 of 10

2 of 10

2 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

1 of 10

Human Disease Associations

FlyBase Human Disease Model Reports

Disease Model Summary Ribbon

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Allele

Disease

Evidence

References

Potential Models Based on Orthology ( 0 )

Human Ortholog

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Allele

Disease

Interaction

References

Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)

Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.

Homo sapiens (Human)

Gene name

Score

OMIM

OMIM Phenotype

DO term

Complementation?

Transgene?

IGSF9; immunoglobulin superfamily member 9

6 of 15

IGSF9B; immunoglobulin superfamily member 9B

5 of 15

Functional Complementation Data

Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.

Interactions

Summary of Physical Interactions

esyN Network Diagram

Interactions Browser

View in Interactions Browser

Please see the Physical Interaction reports below for full details

protein-protein

Physical Interaction

Assay

References

bead aggregation assay, fluorescence microscopy, inferred by author

(Cameron et al., 2013)

anti tag coimmunoprecipitation, anti tag western blot

(Cameron et al., 2013)

Summary of Genetic Interactions

esyN Network Diagram

esyN Network Key:

Suppression

Enhancement

View in Interactions Browser

Please look at the allele data for full details of the genetic interactions

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

suppressible

(Cameron et al., 2013)

Starting gene(s)

Interaction type

Interacting gene(s)

Reference

suppressible

(Cameron et al., 2013)

suppressible

(Cameron et al., 2013)

External Data

Subunit Structure (UniProtKB)

Interacts with tutl.

(UniProt, Q9U4G1 )

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0028482

MIST (protein-protein) - An integrated Molecular Interaction Database

bdl

Pathways

Signaling Pathways (FlyBase)

Metabolic Pathways

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0028482

External Data

Linkouts

Genomic Location and Detailed Mapping Data

Chromosome (arm)

2L

Recombination map

2-12

Cytogenetic map

Sequence location

2L:4,324,554..4,331,830 [+]

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

24E1-24E1

Limits computationally determined from genome sequence between P{PZ}tutl⁰¹⁰⁸⁵ and P{EP}Traf1^EP578

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

2-12

(FlyBase, 2016)

2-13.1

(Comeron et al., 2012)

Left of (cM)

Right of (cM)

Notes

Stocks and Reagents

Stocks (7)

Aberrations including deletions of this gene Aberrations including duplications of this gene

31974

y¹ v¹; P{TRiP.JF03408}attP2

65682

w¹¹¹⁸; PBac{IT.GAL4}bdl^1368-G4

37006

y¹ w^*; Mi{MIC}bdl^MI03534

22846

y¹ w^67c23; Mi{ET1}bdl^MB00585

66898

y¹ w^*; Mi{Trojan-GAL4.0}bdl^{MI03534-TG4.0}

v109857

P{KK110829}VIE-260B

v4806

w¹¹¹⁸; P{GD2597}v4806

Genomic Clones (17)

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones (37)

Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA clones, fully sequenced

BDGP DGC clones

Other clones

RT01690

Drosophila Genomics Resource Center cDNA clones

For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

FBgn0028482

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi and Array Information

Linkouts

DRSC - Results frm RNAi screens

FBgn0028482

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

33635

Antibody Information

Laboratory Generated Antibodies

polyclonal

(Cameron et al., 2013)

Commercially Available Antibodies

Other Information

Relationship to Other Genes

Source for database identify of

Source for identity of: bdl CG16857

(Cameron et al., 2013)

Source for database merge of

Additional comments

Other Comments

Origin and Etymology

Discoverer

Etymology

Identification

External Crossreferences and Linkouts ( 48 )

Sequence Crossreferences

NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.

33635

GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.

GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.

RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.

UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.

Q9U4G1

UniProt/Swiss-Prot - Manually annotated and reviewed records of protein sequence and functional information

Q9U4G1

Other crossreferences

AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.

Q9U4G1

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

FBgn0028482

Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones

FBgn0028482

DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species

33635/tissue=All

EMBL-EBI Single Cell Expression Atlas - Single cell expression across species

FBgn0028482

Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.

CG16857_1

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

FBgn0028482

FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data

FBgn0028482

Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns

Flygut - An atlas of the Drosophila adult midgut

FBgn0028482

FlyMet - A comprehensive tissue-specific metabolomics resource for Drosophila.

FBgn0028482

GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents

33635

iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)

TC008292

InterPro - A database of protein families, domains and functional sites

KEGG Genes - Molecular building blocks of life in the genomic space.

Dmel_CG16857

MARRVEL_MODEL - MARRVEL (model organism gene)

33635

modMine - A data warehouse for the modENCODE project

FBgn0028482

Linkouts

DroID - A comprehensive database of gene and protein interactions.

FBgn0028482

DRSC - Results frm RNAi screens

FBgn0028482

FlyCyc Genes - Genes from a BioCyc PGDB for Dmel

FBGN0028482

FlyMine - An integrated database for Drosophila genomics

FBgn0028482

Interactive Fly - A cyberspace guide to Drosophila development and metazoan evolution

Interactive Fly

MIST (protein-protein) - An integrated Molecular Interaction Database

bdl

Synonyms and Secondary IDs (7)

Reported As

Symbol Synonym

BcDNA:GH11322

(Bodily et al., 2001)

CG16857

(Aradska et al., 2015, Hosono et al., 2015, Sytnikova et al., 2014, Zhou et al., 2014, Cameron et al., 2013, Ozkan et al., 2013, Sen et al., 2013, Jin et al., 2009, Keleman et al., 2009.8.5, Perkins et al., 2009)

CT35491

(Hynes and Zhao, 2000)

GH11322

(Xu et al., 2004)

bdl

(Shaw et al., 2019, Lee et al., 2018, Chen et al., 2017, Cameron et al., 2016, Clandinin and Owens, 2016-, Gene Disruption Project members, 2016-, Cameron et al., 2013)

borderless

(Cameron et al., 2016)

Name Synonyms

Borderless

(Bittern et al., 2021)

borderless

(Cameron et al., 2013)

Secondary FlyBase IDs

Datasets (5)

Study focus (0)

Experimental Role

Project

Project Type

Title

Study result (5)

Result

Result Type

Title

scRNAseq_2020_Cattenoz_NI_seq_clustering

cell clustering analysis

Clustering analysis of hemocytes from non-infested third instar larvae

scRNAseq_2020_Cattenoz_WI_seq_clustering

cell clustering analysis

Clustering analysis of hemocytes from wasp-infested third instar larvae

scRNAseq_2020_Cho_NI96LG_seq_clustering

cell clustering analysis

Clustering analysis of lymph gland cells from non-infested larvae at 96 h after egg-laying

scRNAseq_2020_Cho_NI120LG_seq_clustering

cell clustering analysis

Clustering analysis of lymph gland cells from non-infested larvae at 120 h after egg-laying

scRNAseq_2020_Cho_NI120HL_seq_clustering

cell clustering analysis

Clustering analysis of circulating hemocytes from non-infested larvae at 120 h after egg-laying

References (51)