Gene Dmel\CG16857

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General Information

Symbol

Dmel\CG16857

Species

D. melanogaster

Name

Annotation symbol

CG16857

Feature type

protein_coding_gene

FlyBase ID

FBgn0028482

Gene Model Status

Current

Stock availability

9 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

24E1-24E1

Sequence location

2L:4,324,554..4,331,830 [+]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG16857 (FBgn0028482). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. Based on sequence similarity, it is predicted to be involved in the biological process: cell adhesion. 9 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Fibronectin, type III; Immunoglobulin I-set; Immunoglobulin V-set; Immunoglobulin subtype; Immunoglobulin subtype 2; Immunoglobulin-like domain; Immunoglobulin-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult eye, adult central nervous system. Expression at moderate levels in the following post-embryonic organs or tissues: adult head. Comments on Affy2 ProbeSet: ProbeSet 1624256_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG16857. Gene sequence location is 2L:4324554..4331830.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

24E1-24E1

Limits computationally determined from genome sequence between P{PZ}tutl⁰¹⁰⁸⁵ and P{EP}Traf1^EP578

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG16857 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.47

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG16857-RA

FBtr0077425

NM_134978

2730

719

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG16857-PA

FBpp0077115

81.2

719

6.27

NP_608822

AAF51028

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Immunoglobulin subtype 2 (IPR003598)

Immunoglobulin subtype (IPR003599)

Fibronectin, type III (IPR003961)

Immunoglobulin-like domain (IPR007110)

Immunoglobulin V-set (IPR013106)

Immunoglobulin-like fold (IPR013783)

Immunoglobulin I-set (IPR013098)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

expression microarray

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

eye

(Xu et al., 2004)

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 13 -- 16

dorsal sensory complex proper primordium

(Fisher et al., 2012)

Comment:reported as dorsal/lateral sensory complexes

embryonic dorsal epidermis

(Fisher et al., 2012)

Additional Descriptive Data

Eye-enriched transcripts determined by ratio of expression level in wild-type heads. versus expression level in so heads.

(Xu et al., 2004)

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult eye, adult central nervous system. Expression at moderate levels in the following post-embryonic organs or tissues: adult head.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		81.45
Larval Midgut		13.1
Larval Hindgut		14.1
Larval Malpighian Tubules		10.1
Larval Fat Body		28.1
Larval Salivary Gland		5
Larval Trachea		20.275
Larval Carcass		18.525
Adult Head		414.8
Adult Eye		1339.825
Adult Brain		553
Adult Thoracic-Abdominal Ganglion		893.3
Adult Crop		29.6
Adult Midgut		13.8
Adult Hindgut		22.4
Adult Malpighian Tubules		7.5
Adult Fat Body		18.5
Adult Salivary Gland		6.4
Adult Heart		34.025
Adult VirginFemale Spermatheca		7.1
Adult InseminatedFemale Spermatheca		11.6
Adult Ovary		13.4
Adult Testis		23.8
Adult Male Accessory Gland		40.2
Adult Carcass		61.2
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		81.45
Larval Midgut		13.1
Larval Hindgut		14.1
Larval Malpighian Tubules		10.1
Larval Fat Body		28.1
Larval Salivary Gland		5
Larval Trachea		20.275
Larval Carcass		18.525
Adult Head		414.8
Adult Eye		(1339.825)
Adult Brain		(553)
Adult Thoracic-Abdominal Ganglion		(893.3)
Adult Crop		29.6
Adult Midgut		13.8
Adult Hindgut		22.4
Adult Malpighian Tubules		7.5
Adult Fat Body		18.5
Adult Salivary Gland		6.4
Adult Heart		34.025
Adult VirginFemale Spermatheca		7.1
Adult InseminatedFemale Spermatheca		11.6
Adult Ovary		13.4
Adult Testis		23.8
Adult Male Accessory Gland		40.2
Adult Carcass		61.2
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		81.45
Larval Midgut		13.1
Larval Hindgut		14.1
Larval Malpighian Tubules		10.1
Larval Fat Body		28.1
Larval Salivary Gland		5
Larval Trachea		20.275
Larval Carcass		18.525
Adult Head		414.8
Adult Eye		(1339.825)
Adult Brain		553
Adult Thoracic-Abdominal Ganglion		893.3
Adult Crop		29.6
Adult Midgut		13.8
Adult Hindgut		22.4
Adult Malpighian Tubules		7.5
Adult Fat Body		18.5
Adult Salivary Gland		6.4
Adult Heart		34.025
Adult VirginFemale Spermatheca		7.1
Adult InseminatedFemale Spermatheca		11.6
Adult Ovary		13.4
Adult Testis		23.8
Adult Male Accessory Gland		40.2
Adult Carcass		61.2
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		81.45
Larval Midgut		13.1
Larval Hindgut		14.1
Larval Malpighian Tubules		10.1
Larval Fat Body		28.1
Larval Salivary Gland		5
Larval Trachea		20.275
Larval Carcass		18.525
Adult Head		414.8
Adult Eye		1339.825
Adult Brain		553
Adult Thoracic-Abdominal Ganglion		893.3
Adult Crop		29.6
Adult Midgut		13.8
Adult Hindgut		22.4
Adult Malpighian Tubules		7.5
Adult Fat Body		18.5
Adult Salivary Gland		6.4
Adult Heart		34.025
Adult VirginFemale Spermatheca		7.1
Adult InseminatedFemale Spermatheca		11.6
Adult Ovary		13.4
Adult Testis		23.8
Adult Male Accessory Gland		40.2
Adult Carcass		61.2
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		81.45
Larval Midgut		13.1
Larval Hindgut		14.1
Larval Malpighian Tubules		10.1
Larval Fat Body		28.1
Larval Salivary Gland		5
Larval Trachea		20.275
Larval Carcass		18.525
Adult Head		414.8
Adult Eye		1339.825
Adult Brain		553
Adult Thoracic-Abdominal Ganglion		893.3
Adult Crop		29.6
Adult Midgut		13.8
Adult Hindgut		22.4
Adult Malpighian Tubules		7.5
Adult Fat Body		18.5
Adult Salivary Gland		6.4
Adult Heart		34.025
Adult VirginFemale Spermatheca		7.1
Adult InseminatedFemale Spermatheca		11.6
Adult Ovary		13.4
Adult Testis		23.8
Adult Male Accessory Gland		40.2
Adult Carcass		61.2
Expression Level Scale		None Low Moderate High Very high

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		81.45
Larval Midgut		13.1
Larval Hindgut		14.1
Larval Malpighian Tubules		10.1
Larval Fat Body		28.1
Larval Salivary Gland		5
Larval Trachea		20.275
Larval Carcass		18.525
Adult Head		414.8
Adult Eye		(1339.825)
Adult Brain		553
Adult Thoracic-Abdominal Ganglion		(893.3)
Adult Crop		29.6
Adult Midgut		13.8
Adult Hindgut		22.4
Adult Malpighian Tubules		7.5
Adult Fat Body		18.5
Adult Salivary Gland		6.4
Adult Heart		34.025
Adult VirginFemale Spermatheca		7.1
Adult InseminatedFemale Spermatheca		11.6
Adult Ovary		13.4
Adult Testis		23.8
Adult Male Accessory Gland		40.2
Adult Carcass		61.2
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		81.45
Larval Midgut		13.1
Larval Hindgut		14.1
Larval Malpighian Tubules		10.1
Larval Fat Body		28.1
Larval Salivary Gland		5
Larval Trachea		20.275
Larval Carcass		18.525
Adult Head		414.8
Adult Eye		1339.825
Adult Brain		553
Adult Thoracic-Abdominal Ganglion		893.3
Adult Crop		29.6
Adult Midgut		13.8
Adult Hindgut		22.4
Adult Malpighian Tubules		7.5
Adult Fat Body		18.5
Adult Salivary Gland		6.4
Adult Heart		34.025
Adult VirginFemale Spermatheca		7.1
Adult InseminatedFemale Spermatheca		11.6
Adult Ovary		13.4
Adult Testis		23.8
Adult Male Accessory Gland		40.2
Adult Carcass		61.2
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		81.45
Larval Midgut		13.1
Larval Hindgut		14.1
Larval Malpighian Tubules		10.1
Larval Fat Body		28.1
Larval Salivary Gland		5
Larval Trachea		20.275
Larval Carcass		18.525
Adult Head		414.8
Adult Eye		1339.825
Adult Brain		553
Adult Thoracic-Abdominal Ganglion		893.3
Adult Crop		29.6
Adult Midgut		13.8
Adult Hindgut		22.4
Adult Malpighian Tubules		7.5
Adult Fat Body		18.5
Adult Salivary Gland		6.4
Adult Heart		34.025
Adult VirginFemale Spermatheca		7.1
Adult InseminatedFemale Spermatheca		11.6
Adult Ovary		13.4
Adult Testis		23.8
Adult Male Accessory Gland		40.2
Adult Carcass		61.2
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	414.8
NA	Eye	1339.825
NA	Brain	553
81.45	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	893.3
NA	Crop	29.6
no informative data	Midgut	no informative data
no informative data	Hindgut	22.4
no informative data	Malpighian Tubules	7.5
28.1	Fat Body	no informative data
5	Salivary Gland	6.4
NA	Heart	34.025
no informative data	Trachea	NA
NA	VirginFemale Spermatheca	7.1
NA	InseminatedFemale Spermatheca	no informative data
NA	Ovary	13.4
NA	Testis	23.8
NA	Male Accessory Gland	no informative data
no informative data	Carcass	61.2

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1
central nervous system, larvae L3		3
central nervous system, pupae P8		9
head, virgin 1-day female		81
head, virgin 4-day female		48
head, virgin 20-day female		18
head, mated 1-day female		72
head, mated 4-day female		46
head, mated 20-day female		15
head, mated 1-day male		130
head, mated 4-day male		77
head, mated 20-day male		45
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		1
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		2
fat body, white prepupae		1
fat body, pupae P8		8
carcass, larvae L3 wandering		2
carcass, 1-day adult		10
carcass, 4-day adult		7
carcass, 20-day adult		5
ovary, virgin 4-day female		0
ovary, mated 4-day female		1
testis, mated 4-day male		2
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1
central nervous system, larvae L3		3
central nervous system, pupae P8		9
head, virgin 1-day female		(81)
head, virgin 4-day female		(48)
head, virgin 20-day female		18
head, mated 1-day female		(72)
head, mated 4-day female		(46)
head, mated 20-day female		15
head, mated 1-day male		(130)
head, mated 4-day male		(77)
head, mated 20-day male		(45)
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		1
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		2
fat body, white prepupae		1
fat body, pupae P8		8
carcass, larvae L3 wandering		2
carcass, 1-day adult		10
carcass, 4-day adult		7
carcass, 20-day adult		5
ovary, virgin 4-day female		0
ovary, mated 4-day female		1
testis, mated 4-day male		2
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1
central nervous system, larvae L3		3
central nervous system, pupae P8		9
head, virgin 1-day female		81
head, virgin 4-day female		48
head, virgin 20-day female		18
head, mated 1-day female		72
head, mated 4-day female		46
head, mated 20-day female		15
head, mated 1-day male		(130)
head, mated 4-day male		77
head, mated 20-day male		45
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		1
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		2
fat body, white prepupae		1
fat body, pupae P8		8
carcass, larvae L3 wandering		2
carcass, 1-day adult		10
carcass, 4-day adult		7
carcass, 20-day adult		5
ovary, virgin 4-day female		0
ovary, mated 4-day female		1
testis, mated 4-day male		2
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1
central nervous system, larvae L3		3
central nervous system, pupae P8		9
head, virgin 1-day female		81
head, virgin 4-day female		48
head, virgin 20-day female		18
head, mated 1-day female		72
head, mated 4-day female		46
head, mated 20-day female		15
head, mated 1-day male		130
head, mated 4-day male		77
head, mated 20-day male		45
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		1
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		2
fat body, white prepupae		1
fat body, pupae P8		8
carcass, larvae L3 wandering		2
carcass, 1-day adult		10
carcass, 4-day adult		7
carcass, 20-day adult		5
ovary, virgin 4-day female		0
ovary, mated 4-day female		1
testis, mated 4-day male		2
accessory gland, mated 4-day male		1
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1
central nervous system, larvae L3		3
central nervous system, pupae P8		9
head, virgin 1-day female		81
head, virgin 4-day female		48
head, virgin 20-day female		18
head, mated 1-day female		72
head, mated 4-day female		46
head, mated 20-day female		15
head, mated 1-day male		130
head, mated 4-day male		77
head, mated 20-day male		45
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		1
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		2
fat body, white prepupae		1
fat body, pupae P8		8
carcass, larvae L3 wandering		2
carcass, 1-day adult		10
carcass, 4-day adult		7
carcass, 20-day adult		5
ovary, virgin 4-day female		0
ovary, mated 4-day female		1
testis, mated 4-day male		2
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1
central nervous system, larvae L3		3
central nervous system, pupae P8		9
head, virgin 1-day female		(81)
head, virgin 4-day female		(48)
head, virgin 20-day female		18
head, mated 1-day female		(72)
head, mated 4-day female		(46)
head, mated 20-day female		15
head, mated 1-day male		(130)
head, mated 4-day male		(77)
head, mated 20-day male		(45)
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		1
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		2
fat body, white prepupae		1
fat body, pupae P8		8
carcass, larvae L3 wandering		2
carcass, 1-day adult		10
carcass, 4-day adult		7
carcass, 20-day adult		5
ovary, virgin 4-day female		0
ovary, mated 4-day female		1
testis, mated 4-day male		2
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1
central nervous system, larvae L3		3
central nervous system, pupae P8		9
head, virgin 1-day female		81
head, virgin 4-day female		48
head, virgin 20-day female		18
head, mated 1-day female		72
head, mated 4-day female		46
head, mated 20-day female		15
head, mated 1-day male		130
head, mated 4-day male		77
head, mated 20-day male		45
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		1
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		2
fat body, white prepupae		1
fat body, pupae P8		8
carcass, larvae L3 wandering		2
carcass, 1-day adult		10
carcass, 4-day adult		7
carcass, 20-day adult		5
ovary, virgin 4-day female		0
ovary, mated 4-day female		1
testis, mated 4-day male		2
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		1
central nervous system, larvae L3		3
central nervous system, pupae P8		9
head, virgin 1-day female		81
head, virgin 4-day female		48
head, virgin 20-day female		18
head, mated 1-day female		72
head, mated 4-day female		46
head, mated 20-day female		15
head, mated 1-day male		130
head, mated 4-day male		77
head, mated 20-day male		45
salivary gland, larvae L3 wandering		0
salivary gland, white prepupae		1
digestive system, larvae L3 wandering		0
digestive system, 1-day adult		1
digestive system, 4-day adult		0
digestive system, 20-day adult		0
fat body, larvae L3 wandering		2
fat body, white prepupae		1
fat body, pupae P8		8
carcass, larvae L3 wandering		2
carcass, 1-day adult		10
carcass, 4-day adult		7
carcass, 20-day adult		5
ovary, virgin 4-day female		0
ovary, mated 4-day female		1
testis, mated 4-day male		2
accessory gland, mated 4-day male		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of extremely low expression. Peak expression observed in adult male stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		1
embryo 10-12hr		1
embryo 12-14hr		2
embryo 14-16hr		8
embryo 16-18hr		15
embryo 18-20hr		24
embryo 20-22hr		14
embryo 22-24hr		14
larva L1		9
larva L2		4
larva L3 12hr old		4
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		3
larva L3 puffstage 7-9		2
white prepupae new		2
white prepupae 12hr		4
white prepupae 24hr		4
pupae 2d postWPP		10
pupae 3d postWPP		17
pupae 4d postWPP		42
adult male 01day		53
adult male 05day		37
adult male 30day		28
adult female 01day		32
adult female 05day		7
adult female 30day		6
Expression Level Scale		Very low Low Moderate Moderately high High

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		1
embryo 10-12hr		1
embryo 12-14hr		2
embryo 14-16hr		8
embryo 16-18hr		15
embryo 18-20hr		24
embryo 20-22hr		14
embryo 22-24hr		14
larva L1		9
larva L2		4
larva L3 12hr old		4
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		3
larva L3 puffstage 7-9		2
white prepupae new		2
white prepupae 12hr		4
white prepupae 24hr		4
pupae 2d postWPP		10
pupae 3d postWPP		17
pupae 4d postWPP		(42)
adult male 01day		(53)
adult male 05day		(37)
adult male 30day		(28)
adult female 01day		(32)
adult female 05day		7
adult female 30day		6
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		1
embryo 10-12hr		1
embryo 12-14hr		2
embryo 14-16hr		8
embryo 16-18hr		15
embryo 18-20hr		24
embryo 20-22hr		14
embryo 22-24hr		14
larva L1		9
larva L2		4
larva L3 12hr old		4
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		3
larva L3 puffstage 7-9		2
white prepupae new		2
white prepupae 12hr		4
white prepupae 24hr		4
pupae 2d postWPP		10
pupae 3d postWPP		17
pupae 4d postWPP		42
adult male 01day		53
adult male 05day		37
adult male 30day		28
adult female 01day		32
adult female 05day		7
adult female 30day		6
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		1
embryo 10-12hr		1
embryo 12-14hr		2
embryo 14-16hr		8
embryo 16-18hr		15
embryo 18-20hr		24
embryo 20-22hr		14
embryo 22-24hr		14
larva L1		9
larva L2		4
larva L3 12hr old		4
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		3
larva L3 puffstage 7-9		2
white prepupae new		2
white prepupae 12hr		4
white prepupae 24hr		4
pupae 2d postWPP		10
pupae 3d postWPP		17
pupae 4d postWPP		42
adult male 01day		53
adult male 05day		37
adult male 30day		28
adult female 01day		32
adult female 05day		7
adult female 30day		6
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		1
embryo 10-12hr		1
embryo 12-14hr		2
embryo 14-16hr		8
embryo 16-18hr		15
embryo 18-20hr		24
embryo 20-22hr		14
embryo 22-24hr		14
larva L1		9
larva L2		4
larva L3 12hr old		4
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		3
larva L3 puffstage 7-9		2
white prepupae new		2
white prepupae 12hr		4
white prepupae 24hr		4
pupae 2d postWPP		10
pupae 3d postWPP		17
pupae 4d postWPP		42
adult male 01day		53
adult male 05day		37
adult male 30day		28
adult female 01day		32
adult female 05day		7
adult female 30day		6
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		1
embryo 10-12hr		1
embryo 12-14hr		2
embryo 14-16hr		8
embryo 16-18hr		15
embryo 18-20hr		24
embryo 20-22hr		14
embryo 22-24hr		14
larva L1		9
larva L2		4
larva L3 12hr old		4
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		3
larva L3 puffstage 7-9		2
white prepupae new		2
white prepupae 12hr		4
white prepupae 24hr		4
pupae 2d postWPP		10
pupae 3d postWPP		17
pupae 4d postWPP		(42)
adult male 01day		(53)
adult male 05day		(37)
adult male 30day		28
adult female 01day		32
adult female 05day		7
adult female 30day		6
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		1
embryo 10-12hr		1
embryo 12-14hr		2
embryo 14-16hr		8
embryo 16-18hr		15
embryo 18-20hr		24
embryo 20-22hr		14
embryo 22-24hr		14
larva L1		9
larva L2		4
larva L3 12hr old		4
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		3
larva L3 puffstage 7-9		2
white prepupae new		2
white prepupae 12hr		4
white prepupae 24hr		4
pupae 2d postWPP		10
pupae 3d postWPP		17
pupae 4d postWPP		42
adult male 01day		53
adult male 05day		37
adult male 30day		28
adult female 01day		32
adult female 05day		7
adult female 30day		6
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		0
embryo 02-04hr		0
embryo 04-06hr		0
embryo 06-08hr		0
embryo 08-10hr		1
embryo 10-12hr		1
embryo 12-14hr		2
embryo 14-16hr		8
embryo 16-18hr		15
embryo 18-20hr		24
embryo 20-22hr		14
embryo 22-24hr		14
larva L1		9
larva L2		4
larva L3 12hr old		4
larva L3 puffstage 1-2		3
larva L3 puffstage 3-6		3
larva L3 puffstage 7-9		2
white prepupae new		2
white prepupae 12hr		4
white prepupae 24hr		4
pupae 2d postWPP		10
pupae 3d postWPP		17
pupae 4d postWPP		42
adult male 01day		53
adult male 05day		37
adult male 30day		28
adult female 01day		32
adult female 05day		7
adult female 30day		6
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		20
embryonic 1182-4H		121
embryonic GM2		0
embryonic Kc167		0
embryonic S1		1
embryonic S3		0
leg disc CME L1		22
wing disc CME-W2		0
wing disc ML-DmD8		0
wing disc ML-DmD9		2
wing disc ML-DmD16-c3		6
wing disc ML-DmD21		9
wing disc ML-DmD32		12
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		32
antennal disc ML-DmD20-c5		64
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		3
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		20
embryonic 1182-4H		(121)
embryonic GM2		0
embryonic Kc167		0
embryonic S1		1
embryonic S3		0
leg disc CME L1		22
wing disc CME-W2		0
wing disc ML-DmD8		0
wing disc ML-DmD9		2
wing disc ML-DmD16-c3		6
wing disc ML-DmD21		9
wing disc ML-DmD32		12
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		(32)
antennal disc ML-DmD20-c5		(64)
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		3
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		2
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		20
embryonic 1182-4H		(121)
embryonic GM2		0
embryonic Kc167		0
embryonic S1		1
embryonic S3		0
leg disc CME L1		22
wing disc CME-W2		0
wing disc ML-DmD8		0
wing disc ML-DmD9		2
wing disc ML-DmD16-c3		6
wing disc ML-DmD21		9
wing disc ML-DmD32		12
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		32
antennal disc ML-DmD20-c5		64
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		3
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		20
embryonic 1182-4H		121
embryonic GM2		0
embryonic Kc167		0
embryonic S1		1
embryonic S3		0
leg disc CME L1		22
wing disc CME-W2		0
wing disc ML-DmD8		0
wing disc ML-DmD9		2
wing disc ML-DmD16-c3		6
wing disc ML-DmD21		9
wing disc ML-DmD32		12
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		32
antennal disc ML-DmD20-c5		64
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		3
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		2
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		20
embryonic 1182-4H		121
embryonic GM2		0
embryonic Kc167		0
embryonic S1		1
embryonic S3		0
leg disc CME L1		22
wing disc CME-W2		0
wing disc ML-DmD8		0
wing disc ML-DmD9		2
wing disc ML-DmD16-c3		6
wing disc ML-DmD21		9
wing disc ML-DmD32		12
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		32
antennal disc ML-DmD20-c5		64
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		3
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		20
embryonic 1182-4H		(121)
embryonic GM2		0
embryonic Kc167		0
embryonic S1		1
embryonic S3		0
leg disc CME L1		22
wing disc CME-W2		0
wing disc ML-DmD8		0
wing disc ML-DmD9		2
wing disc ML-DmD16-c3		6
wing disc ML-DmD21		9
wing disc ML-DmD32		12
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		32
antennal disc ML-DmD20-c5		(64)
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		3
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		2
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		20
embryonic 1182-4H		121
embryonic GM2		0
embryonic Kc167		0
embryonic S1		1
embryonic S3		0
leg disc CME L1		22
wing disc CME-W2		0
wing disc ML-DmD8		0
wing disc ML-DmD9		2
wing disc ML-DmD16-c3		6
wing disc ML-DmD21		9
wing disc ML-DmD32		12
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		32
antennal disc ML-DmD20-c5		64
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		3
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		0
Schneider line 2 Sg4		20
embryonic 1182-4H		121
embryonic GM2		0
embryonic Kc167		0
embryonic S1		1
embryonic S3		0
leg disc CME L1		22
wing disc CME-W2		0
wing disc ML-DmD8		0
wing disc ML-DmD9		2
wing disc ML-DmD16-c3		6
wing disc ML-DmD21		9
wing disc ML-DmD32		12
haltere disc ML-DmD17-c3		0
eye-antennal disc ML-DmD11		32
antennal disc ML-DmD20-c5		64
mixed discs ML-DmD4-c1		0
CNS ML-DmBG1-c1		3
CNS ML-DmBG2-c2		0
tumorous blood cells mbn2		0
ovary fGS/OSS		0
ovary OSC		0
ovary OSS		2
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		5
cold shock, 4-day adult		5
heat shock, 4-day adult		4
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		4
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		10
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		11
Ethanol 2.5% 3 hrs, larvae L3		9
Ethanol 5% 3 hrs, larvae L3		2
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		8
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		11
Paraquat 10 mM 48 hrs, 4-day adult		18
Rotenone 2 μg 12 hrs, larvae L3		1
Rotenone 8 μg 12 hrs, larvae L3		1
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		5
cold shock, 4-day adult		5
heat shock, 4-day adult		4
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		4
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		10
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		11
Ethanol 2.5% 3 hrs, larvae L3		9
Ethanol 5% 3 hrs, larvae L3		2
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		8
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		11
Paraquat 10 mM 48 hrs, 4-day adult		18
Rotenone 2 μg 12 hrs, larvae L3		1
Rotenone 8 μg 12 hrs, larvae L3		1
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		5
cold shock, 4-day adult		5
heat shock, 4-day adult		4
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		4
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		10
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		11
Ethanol 2.5% 3 hrs, larvae L3		9
Ethanol 5% 3 hrs, larvae L3		2
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		8
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		11
Paraquat 10 mM 48 hrs, 4-day adult		18
Rotenone 2 μg 12 hrs, larvae L3		1
Rotenone 8 μg 12 hrs, larvae L3		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		5
cold shock, 4-day adult		5
heat shock, 4-day adult		4
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		4
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		10
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		11
Ethanol 2.5% 3 hrs, larvae L3		9
Ethanol 5% 3 hrs, larvae L3		2
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		8
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		11
Paraquat 10 mM 48 hrs, 4-day adult		18
Rotenone 2 μg 12 hrs, larvae L3		1
Rotenone 8 μg 12 hrs, larvae L3		1
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		5
cold shock, 4-day adult		5
heat shock, 4-day adult		4
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		4
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		10
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		11
Ethanol 2.5% 3 hrs, larvae L3		9
Ethanol 5% 3 hrs, larvae L3		2
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		8
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		11
Paraquat 10 mM 48 hrs, 4-day adult		18
Rotenone 2 μg 12 hrs, larvae L3		1
Rotenone 8 μg 12 hrs, larvae L3		1
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		5
cold shock, 4-day adult		5
heat shock, 4-day adult		4
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		4
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		10
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		11
Ethanol 2.5% 3 hrs, larvae L3		9
Ethanol 5% 3 hrs, larvae L3		2
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		8
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		11
Paraquat 10 mM 48 hrs, 4-day adult		18
Rotenone 2 μg 12 hrs, larvae L3		1
Rotenone 8 μg 12 hrs, larvae L3		1
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		5
cold shock, 4-day adult		5
heat shock, 4-day adult		4
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		4
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		10
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		11
Ethanol 2.5% 3 hrs, larvae L3		9
Ethanol 5% 3 hrs, larvae L3		2
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		8
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		11
Paraquat 10 mM 48 hrs, 4-day adult		18
Rotenone 2 μg 12 hrs, larvae L3		1
Rotenone 8 μg 12 hrs, larvae L3		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		5
cold shock, 4-day adult		5
heat shock, 4-day adult		4
Cadmium 50 mM 6 hrs, larvae L3		1
Cadmium 50 mM 12 hrs, larvae L3		1
Cadmium 50 mM 48 hrs, 4-day adult		4
Cadmium 100 mM 48 hrs, 4-day adult		7
Copper 0.5 mM 12 hrs, larvae L3		1
Copper 15 mM 48 hrs, 4-day adult		10
Zinc 5 mM 12 hrs, larvae L3		1
Zinc 4.5 mM 48 hrs, 4-day adult		11
Ethanol 2.5% 3 hrs, larvae L3		9
Ethanol 5% 3 hrs, larvae L3		2
Ethanol 10% 3 hrs, larvae L3		2
Caffeine 1.5 mg/ml 4 hrs, larvae L3		1
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		8
Caffeine 25 mg/ml 48 hrs, 4-day adult		4
Paraquat 5 mM 48 hrs, 4-day adult		11
Paraquat 10 mM 48 hrs, 4-day adult		18
Rotenone 2 μg 12 hrs, larvae L3		1
Rotenone 8 μg 12 hrs, larvae L3		1
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

GH11322

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0028482

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG16857-RA

FlyExpress - Embryonic expression images (BDGP data)

•

Show all FlyExpress processed images for CG16857

Stages(s) 13-16

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable, with Scer\GAL4^pnr-MD237

Phenotype manifest in

Allele

Classical Alleles ( 4 )

For All Classical Alleles Show

Allele of CG16857	Mutagen	Stocks	Known lesion
CG16857^c01958		1	--
CG16857^f02225	piggyBac transposase	1	--
CG16857^MB00585		1	--
CG16857^MI03534		1	--

Alleles Carried on Transgenic Constructs ( 5 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG16857	Mutagen	Stocks	Known lesion
CG16857^GD14358	in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
CG16857^GD101	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG16857^GD2597	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG16857^JF03408	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG16857^KK110829	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Disrupted in

Df(2L)Exel8011

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

Insertions

Type of insertions

Name

Expression data

miscellaneous insertions

Mi{MIC}CG16857^MI03534

PBac{PB}CG16857^c01958

PBac{WH}CG16857^f02225

insertion of enhancer trap binary system

Mi{ET1}CG16857^MB00585

Gene Ontology: Function, Process & Cellular Component ( 1 unique term )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 1 term )

Molecular Function ( 0 terms)

Biological Process

CV term

Evidence

References

cell adhesion

inferred from sequence or structural similarity with EMBL:AF074901

(FlyBase, 1992-)

Cellular Component ( 0 terms)

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG16857 allele

Gene

References

External Data

Linkouts

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0028482

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

33635

Orthologs

OrthoDB Orthologs (30) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG61VKNF

Dipteran inclusive ortholog search

EOG6RXZ7B

Insect inclusive ortholog search

EOG63JB16

Arthropod inclusive ortholog search

No orthologs identified

Metazoa inclusive ortholog search

No orthologs identified

Orthologs in Drosophila Species (EOG61VKNF)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA14181

Drosophila persimilis

Dper\GL14021

Drosophila willistoni

Dwil\GK24612

Drosophila virilis

Dvir\GJ16223

Drosophila mojavensis

Dmoj\GI16510

Drosophila grimshawi

Dgri\GH10067

Orthologs in non-Drosophila Dipterans (EOG6RXZ7B)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL014457

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL003586

Anopheles gambiae

Malaria mosquito

Agam\AGAP008943

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ004822

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ004821

Orthologs in non-Dipteran Insects (EOG63JB16)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\GB53013

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG011341

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH16892

Atta cephalotes

Leafcutter ant

Acep\ACEP11349

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO13450

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO13449

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL22534

Linepithema humile

Argentine ant

Lhum\LH17787

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB19374

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB19376

Solenopsis invicta

Red fire ant

Sinv\SINV16863

Bombyx mori

Silkmoth

Bmor\BGIBMGA005854

Tribolium castaneum

Red flour beetle

Tcas\GLEAN_08292

Orthologs in non-Insect Arthropods (None identified)

No non-Insect Arthropod orthologies identified

Orthologs in non-Arthropod Metazoa (None identified)

No non-Arthropod Metazoa orthologies identified

Human Orthologs (0)

Gene

OMIM

HGNC

AAA Orthologs (10) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila ananassae

Drosophila pseudoobscura pseudoobscura

Dpse\GA14181

Drosophila willistoni

Dwil\GK24612

Drosophila virilis

Dvir\GJ16223

Drosophila mojavensis

Dmoj\GI16510

Drosophila grimshawi

Dgri\GH10067

Stocks & Reagents

Stocks Listed in FlyBase ( 9 )

Bloomington

31974

y¹ v¹; P{TRiP.JF03408}attP2

37006

y¹ w^*; Mi{MIC}CG16857^MI03534

22846

y¹ w^67c23; Mi{ET1}CG16857^MB00585

Harvard

PBac{PB}CG16857^c01958

PBac{WH}CG16857^f02225

VDRC

v24479

w¹¹¹⁸; P{GD101}v24479

v4806

w¹¹¹⁸; P{GD2597}v4806

v36224

w¹¹¹⁸; P{GD14358}v36224/TM3

v36226

w¹¹¹⁸; P{GD14358}v36226/TM3

Genomic Clones ( 1 )

BACR09F08

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 41 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

RT01690

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0028482

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

33635

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_134978

RefSeq (Proteins)

•

NP_608822

DDBJ / EMBL / GenBank

•

Entrez Gene - A searchable database of RefSeq genes.

•

33635

UniProtKB/TrEMBL

•

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Immunoglobulin subtype 2 (IPR003598)

Immunoglobulin subtype (IPR003599)

Fibronectin, type III (IPR003961)

Immunoglobulin-like domain (IPR007110)

Immunoglobulin V-set (IPR013106)

Immunoglobulin-like fold (IPR013783)

Immunoglobulin I-set (IPR013098)

BDGP expression data - Patterns of gene expression in Drosophila embryogenesis

•

GH11322

Linkouts

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0028482

DRSC - Results from RNAi screens.

•

FBgn0028482

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0028482

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG16857-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0028482

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

33635

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

33635

modMine - Data generated by the modENCODE project.

•

FBgn0028482

Synonyms & Secondary IDs ( 4 )

Reported As

Symbol Synonym

BcDNA:GH11322

(Bodily et al., 2001, )

CG16857

(Jin et al., 2009, Perkins et al., 2009, Keleman et al., 2009.8.5)

CT35491

(Hynes and Zhao, 2000)

GH11322

(Xu et al., 2004)

Name Synonym

Secondary FlyBase IDs

References ( 26 )

Generate a list of

All references relating to this gene ( 26 )

List References by type

Research paper ( 5 )
Supplementary material ( 5 )
Personal communication to FlyBase ( 10 )
FlyBase analysis ( 2 )
Website ( 1 )
Curated genome annotation ( 2 )

Recent research papers ( 1 )

Baycin-Hizal et al., 2011, J. Proteome Res. 10(6): 2777--2784: GlycoFly: A Database of Drosophila N-linked Glycoproteins Identified Using SPEG-MS Techniques. [FBrf0213834]

Show all research papers ...