FB2025_01 , released February 20, 2025
Gene: Dmel\EndoGI
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General Information
Symbol
Dmel\EndoGI
Species
D. melanogaster
Name
Endonuclease G inhibitor
Annotation Symbol
CG4930
Feature Type
protein_coding_gene
FlyBase ID
FBgn0028515
Gene Model Status
Current
Stock Availability
9 publicly available
Gene Summary
Endonuclease G inhibitor (EndoGI) encodes an inhibitor of the enzyme encoded by EndoG by tight binding to the enzymatic active site. Since the product of EndoG is mostly or entirely localized in mitochondria, the product of EndoGI has been suggested to protect cells against mis-localization of the enzyme. [Date last reviewed: 2019-03-07] (FlyBase Gene Snapshot)
All Summaries
Also Known As

BG:DS07473.2

Key Links
Genomic Location
Cytogenetic map
35F1-35F1
Sequence location
Recombination map
2-52
RefSeq locus
NT_033779 REGION:16257688..16259511
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
Gene Ontology (GO) Annotations (3 terms)
Molecular Function (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
enables ribonuclease inhibitor activity
inferred from direct assay
(Temme et al., 2009)
Terms Based on Predictions or Assertions (0 terms)
Biological Process (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
involved_in positive regulation of Notch signaling pathway
inferred from mutant phenotype
(O'Keefe et al., 2011)
Terms Based on Predictions or Assertions (0 terms)
Cellular Component (1 term)
Terms Based on Experimental Evidence (1 term)
CV Term
Evidence
References
located_in nucleus
inferred from direct assay
(O'Keefe et al., 2011, Temme et al., 2009)
Terms Based on Predictions or Assertions (0 terms)
Gene Group (FlyBase)
Pathway (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Summaries
Gene Snapshot
Endonuclease G inhibitor (EndoGI) encodes an inhibitor of the enzyme encoded by EndoG by tight binding to the enzymatic active site. Since the product of EndoG is mostly or entirely localized in mitochondria, the product of EndoGI has been suggested to protect cells against mis-localization of the enzyme. [Date last reviewed: 2019-03-07]
Pathway (FlyBase)
Positive Regulators of Notch Signaling Pathway -
The Notch receptor signaling pathway is activated by the binding of the transmembrane receptor Notch (N) to transmembrane ligands, Dl or Ser, presented on adjacent cells. This results in the proteolytic cleavage of N, releasing the intracellular domain (NICD). NICD translocates into the nucleus, interacting with Su(H) and mam to form a transcription complex, which up-regulates transcription of Notch-responsive genes. Positive regulators of the pathway enhance the signal from the sending cell or the response in the receiving cell. (Adapted from FBrf0225731 and FBrf0192604).
Gene Model and Products
Number of Transcripts
3
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\EndoGI for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Structure
Protein 3D structure   (Predicted by AlphaFold)   (AlphaFold entry Q9V3V9)

If you don't see a structure in the viewer, refresh your browser.
Model Confidence:
  • Very high (pLDDT > 90)
  • Confident (90 > pLDDT > 70)
  • Low (70 > pLDDT > 50)
  • Very low (pLDDT < 50)

AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.

Experimentally Determined Structures
Crossreferences
PDB - An information portal to biological macromolecular structures
Comments on Gene Model

Gene model reviewed during 5.44

Gene model reviewed during 5.55

Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
EndoGI-RA
FBtr0080824
NM_135937
1360
359
EndoGI-RB
FBtr0331442
NM_001273560
1406
359
EndoGI-RC
FBtr0331443
NM_001273561
1438
359
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
UniProt
RefSeq ID
GenBank
EndoGI-PA
FBpp0080382
40.6
359
4.20
Q9V3V9
NP_609781
AAF53507
EndoGI-PB
FBpp0303859
40.6
359
4.20
Q9V3V9
NP_001260489
AGB93024
EndoGI-PC
FBpp0303860
40.6
359
4.20
Q9V3V9
NP_001260490
AGB93025
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

359 aa isoforms: EndoGI-PA, EndoGI-PB, EndoGI-PC
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
PDB - An information portal to biological macromolecular structures
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\EndoGI using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Testis-specificity index

The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).

1.75

Transcript Expression
in situ
Stage
Tissue/Position (including subcellular localization)
Reference
wandering third instar larval stage
wing pouch | restricted
(Molnar et al., 2012)
wing hinge primordium | restricted
(Molnar et al., 2012)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
immunolocalization
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage
organism | ubiquitous
(O'Keefe et al., 2011)
embryonic stage 4
organism
(Temme et al., 2009)
larval stage
testis
(O'Keefe et al., 2011)
imaginal disc
(O'Keefe et al., 2011)
larval ventral nerve cord | restricted
(O'Keefe et al., 2011)
larval brain | restricted
(O'Keefe et al., 2011)
embryonic/larval salivary gland
(O'Keefe et al., 2011)
oogenesis
follicle cell
(Temme et al., 2009)
nurse cell
(Temme et al., 2009)
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
western blot
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage -- adult stage
organism
(Temme et al., 2009)
Additional Descriptive Data

EndoGI expression is widespread and predominantly nuclear. It is supplied maternally to the embryo and uniformly labels embryonic nuclei. In larvae, it is ubiquitously expressed in many tissues including imaginal discs and testis. By contrast, only a subset of cells within the larval brain and ventral nerve cord express EndoGI. It is dynamically expressed within the salivary glands, being present in the nucleus in early third instar larvae but absent from most nuclei in late third instar larvae. A small number of salivary gland cells show cytoplasmic localization of EndoGI in late third instar larvae.

(O'Keefe et al., 2011)

EndoGI protein is detected at all stages assayed. EndoGI protein is localized to the nuclei of follicle cells and nurse cells in ovaries.

(Temme et al., 2009)
Marker for
 
Subcellular Localization
CV Term
Evidence
References
located_in nucleus
inferred from direct assay
(O'Keefe et al., 2011, Temme et al., 2009)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

JBrowse - Visual display of RNA-Seq signals

View Dmel\EndoGI in JBrowse
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 6 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 7 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of EndoGI
Transgenic constructs containing regulatory region of EndoGI
Aberrations (Deficiencies and Duplications) ( 2 )
Inferred from experimentation ( 2 )
Gene disrupted in
Df(2L)r10
(Temme et al., 2009)
Df(2L)RA5
(Temme et al., 2009)
Inferred from location ( 4 )
Variants
Variant Molecular Consequences
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
lethal | recessive
partially lethal, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
partially lethal - majority die
viable, with Scer\GAL4Mef2.PR
Sterility
Allele
female fertile
male sterile
male sterile (with Df(2L)RA5)
Other Phenotypes
Allele
abnormal flight
abnormal neuroanatomy | embryonic stage
decreased body size (with Df(2L)RA5)
increased cell number | somatic clone, with Scer\GAL4Act5C.PP
some die during embryonic stage, with Dcr-2UAS.cDa, Scer\GAL4elav.PLu
some die during third instar larval stage
uncoordinated | adult stage (with Df(2L)RA5)
visible, with Scer\GAL4ap-md544
visible, with Scer\GAL4en-e16E
visible (with Df(2L)RA5)
visible | somatic clone, with Scer\GAL4Act5C.PP
Phenotype manifest in
Allele
eye | somatic clone, with Scer\GAL4Act5C.PP
larval intersegmental nerve
larval intersegmental nerve branch ISNb of A1-7
larval segmental nerve branch SNa of A1-7
larval segmental nerve branch SNc of A1-7
leg (with Df(2L)RA5)
wing (with Df(2L)RA5)
wing | posterior, with Scer\GAL4en-e16E
wing disc | somatic clone, with Scer\GAL4Act5C.PP
wing margin bristle, with Scer\GAL4ap-md544
wing vein, with Scer\GAL4en-e16E
Orthologs
Downloads
Download All DIOPT Orthologs
Human Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Homo sapiens (Human) (2)
Hsap\XRCC5
2 of 14
Yes
No
Hsap\XRCC6
1 of 14
No
No
1  
Model Organism Orthologs (via DIOPT v9.1)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
Domainoid
eggNOG
Hieranoid
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Complementation?
Transgene?
Rattus norvegicus (Norway rat) (2)
Rnor\Xrcc5
2 of 14
Yes
No
Rnor\Xrcc6
1 of 14
No
No
Mus musculus (laboratory mouse) (2)
Mmus\Xrcc5
2 of 14
Yes
No
Mmus\Xrcc6
1 of 14
No
No
Xenopus tropicalis (Western clawed frog) (3)
Xtro\tmem169
1 of 13
Yes
No
Xtro\xrcc5
1 of 13
Yes
No
Xtro\xrcc6
1 of 13
Yes
No
Danio rerio (Zebrafish) (2)
Drer\xrcc5
2 of 14
Yes
No
Drer\xrcc6
1 of 14
No
No
Caenorhabditis elegans (Nematode, roundworm) (2)
Cele\cku-80
2 of 14
Yes
No
Cele\cku-70
1 of 14
No
No
Anopheles gambiae (African malaria mosquito) (2)
Agam\AgaP_AGAP009910
2 of 12
Yes
No
Agam\AgaP_AGAP002690
1 of 12
No
No
Arabidopsis thaliana (thale-cress) (2)
Atha\KU70
1 of 13
Yes
No
Atha\KU80
1 of 13
Yes
No
Saccharomyces cerevisiae (Brewer's yeast) (2)
Scer\YKU80
2 of 13
Yes
No
Scer\YKU70
1 of 13
No
No
Schizosaccharomyces pombe (Fission yeast) (2)
Spom\pku70
1 of 12
Yes
No
Spom\pku80
1 of 12
Yes
No
Escherichia coli (enterobacterium) (0)
Other Organism Orthologs (via OrthoDB)
Data provided directly from OrthoDB:EndoGI. Refer to their site for version information.
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v9.1)
Gene Symbol
Score
Source
Compara
Domainoid
eggNOG
Homologene
Inparanoid
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
SonicParanoid
Alignment
Drosophila melanogaster (Fruit fly) (2)
Ku80
4 of 13
Irbp
2 of 13
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 0 )
    Human Ortholog
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v9.1 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    Functional Complementation Data
    Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
    Interactions
    Summary of Physical Interactions
    esyN Network Diagram
    Show neighbor-neighbor interactions:
    Show/hide secondary interactors 
    (data from AllianceMine provided by esyN)
    Select Layout:
    Legend:
    Protein
    RNA
    Selected Interactor(s)
    Other Interaction Browsers
    View in FlyBase Interactions Browser   View in MIST tool (external link)
    Please see the Physical Interaction reports below for full details
    protein-protein
    Physical Interaction
    Assay
    References
    EndoGI - 14-3-3ε
    cosedimentation, molecular weight
    (Temme et al., 2009)
    EndoGI - Acaa
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Akr2E3
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Ald1
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - AnxB10
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Ar1
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Ar2
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - CG14062
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - CG14715
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - CG17778
    two hybrid
    (Hu et al., 2017.6.13)
    EndoGI - CG2852
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - CG5174
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - CG6709
    two hybrid
    (Hu et al., 2017.6.13)
    EndoGI - Calr
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Diap2
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - EndoG
    enzymatic study, autoradiography, cosedimentation, molecular weight, experimental knowledge based
    (Guruharsha et al., 2011, Temme et al., 2009)
    EndoGI - Eno
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Fkbp14
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - GILT2
    two hybrid
    (Hu et al., 2017.6.13)
    EndoGI - Gdi
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Glo1
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - GstO3
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Gtpx
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - HINT1
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Hsp110
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Inos
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Mdh2
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Moe
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Nacα
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Nlp
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Paics
    two hybrid
    (Hu et al., 2017.6.13)
    EndoGI - Pgd
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Prx6c
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Sh3β
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Stip1
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - Uch
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - awd
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - capt
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - cib
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - fabp
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - flr
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - lms
    two hybrid
    (Hu et al., 2017.6.13)
    EndoGI - regucalcin
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - scf
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - scu
    experimental knowledge based
    (Guruharsha et al., 2011)
    EndoGI - sel
    experimental knowledge based
    (Guruharsha et al., 2011)
    Summary of Genetic Interactions
    esyN Network Diagram
    Show/hide secondary interactors 
    (data from AllianceMine provided by esyN)
    esyN Network Key:
    Suppression
    Enhancement
    Other Interaction Browsers
    View in FlyBase Interactions Browser   View in MIST tool (external link)
    Please look at the allele data for full details of the genetic interactions
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    EndoGI
    suppressible
    Abl
    (O'Keefe et al., 2011)
    EndoGI
    suppressible
    mam
    (O'Keefe et al., 2011)
    Starting gene(s)
    Interaction type
    Interacting gene(s)
    Reference
    External Data
    Linkouts
    DroID - A comprehensive database of gene and protein interactions.
    MIST (protein-protein) - An integrated Molecular Interaction Database
    Pathways
    Signaling Pathways (FlyBase)
    Metabolic Pathways
    FlyBase
    External Links
    External Data
    Linkouts
    Class of Gene
    Genomic Location and Detailed Mapping Data
    Chromosome (arm)
    2L
    Recombination map
    2-52
    Cytogenetic map
    35F1-35F1
    Sequence location
    FlyBase Computed Cytological Location
    Cytogenetic map
    Evidence for location
    35F1-35F1
    Limits computationally determined from genome sequence between P{lacW}CycEk05007&P{lacW}CycEk02602 and P{EP}crpEP721&P{lacW}crpk07829
    Experimentally Determined Cytological Location
    Cytogenetic map
    Notes
    References
    Experimentally Determined Recombination Data
    Location

    2-52

    (FlyBase, 2016)

    2-49.3

    (Comeron et al., 2012)
    Left of (cM)
    Right of (cM)
    Notes
    Stocks and Reagents
    Stocks (9)
    Genomic Clones (24)
    cDNA Clones (84)
     

    Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.

    cDNA clones, fully sequenced
    BDGP DGC clones
    Other clones
      Drosophila Genomics Resource Center cDNA clones

      For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

      cDNA Clones, End Sequenced (ESTs)
      BDGP DGC clones
      Other clones
      RNAi and Array Information
      Linkouts
      DRSC - Results frm RNAi screens
      Antibody Information
      Laboratory Generated Antibodies
       

      monoclonal

      (O'Keefe et al., 2011)

      polyclonal

      (Temme et al., 2009)
      Commercially Available Antibodies
       
      Cell Line Information
      Publicly Available Cell Lines
       
        Other Stable Cell Lines
         
          Other Comments
          Relationship to Other Genes
          Source for database merge of
          Additional comments
          Nomenclature History
          Source for database identify of

          Source for identity of: BG:DS07473.2 CG4930

          (Kodira, 1999.11)

          Source for identity of: EndoGI CG4930

          (Temme et al., 2009)
          Nomenclature comments
          Etymology
          Synonyms and Secondary IDs (6)
          Datasets (0)
          Study focus (0)
          Experimental Role
          Project
          Project Type
          Title
          Study result (0)
          Result
          Result Type
          Title
          External Crossreferences and Linkouts ( 41 )
          Sequence Crossreferences
          NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
          GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
          GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
          RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
          UniProt/GCRP - The gene-centric reference proteome (GCRP) provides a 1:1 mapping between genes and UniProt accessions in which a single 'canonical' isoform represents the product(s) of each protein-coding gene.
          UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
          Other crossreferences
          AlphaFold DB - AlphaFold provides open access to protein structure predictions for the human proteome and other key proteins of interest, to accelerate scientific research.
          DRscDB - A single-cell RNA-seq resource for data mining and data comparison across species
          EMBL-EBI Single Cell Expression Atlas - Single cell expression across species
          FlyAtlas2 - A Drosophila melanogaster expression atlas with RNA-Seq, miRNA-Seq and sex-specific data
          FlyMine - An integrated database for Drosophila genomics
          InterPro - A database of protein families, domains and functional sites
          KEGG Genes - Molecular building blocks of life in the genomic space.
          MARRVEL_MODEL - MARRVEL (model organism gene)
          PDB - An information portal to biological macromolecular structures
          Linkouts
          Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
          DroID - A comprehensive database of gene and protein interactions.
          DRSC - Results frm RNAi screens
          Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
          FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
          FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
          Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
          Flygut - An atlas of the Drosophila adult midgut
          MIST (protein-protein) - An integrated Molecular Interaction Database
          References (40)