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Gene Dmel\CG9008

General Information
Symbol	Dmel\CG9008	Species	D. melanogaster
Name		Annotation symbol	CG9008
Feature type	protein_coding_gene	FlyBase ID	FBgn0028540
Gene Model Status	Current	Stock availability	5 publicly available
Also Known As	BG:DS00797.2
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	34D1-34D1	Sequence location	2L:13,774,340..13,780,163 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG9008 (FBgn0028540). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: carbohydrate binding; isomerase activity. There is experimental evidence that it is involved in the biological process: Golgi organization; lipid particle organization. 8 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Aldose 1-epimerase; Glycoside hydrolase-type carbohydrate-binding; Glycoside hydrolase-type carbohydrate-binding, subgroup. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult Malpighian tubules, adult fat body, adult spermathecae. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, larval fat body, larval trachea, adult testis, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1632019_s_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG9008. Gene sequence location is 2L:13774340..13780163.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2012_01	References Vrailas-Mortimer et al., 2011, Dev. Cell 21(4): 783--795 Sequence features HFA01889 BKN30184
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 34D1-34D1   Limits computationally determined from genome sequence between P{lacW}CG7364k07245 and P{lacW}Sosk05224&P{lacW}RpII33k05605
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG9008 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG9008-RA FBtr0080576  NM_135826   1985   297 CG9008-RB FBtr0080577  NM_165055   2202   191
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG9008-PA   FBpp0080153   34.2   297   8.89     NP_609670   AAF53325 CG9008-PB   FBpp0080154   22.6   191   8.10     NP_723835   AAN10845
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Aldose 1-epimerase (IPR008183) Glycoside hydrolase-type carbohydrate-binding (IPR011013) Glycoside hydrolase-type carbohydrate-binding, subgroup (IPR014718)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA697797   AE014134 AAF53325   AE014134 AAN10845   AE003407 AAF44811   AI238795   AI258154   AI260644   AI260878   AI293392   AI293864   AI513328   AI946139   AX094001   AY060305 AAL25344   BF495124   BF497168   BF503292   BF505754   BI169260   BI171032   BI368294   BI373584   BI374707   BI375219   BI483395   BP543295   BP543296   CO191529   CO283673   CO292127   CO298709   CO307179   CO339867   CO340653   CZ482929   CZ482930   CZ482941   CZ482943   EC075084   EC203490   EC246971   EC255871   EC259168   GH944105   GH961468
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8IP67 Q9V3D1
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0028540    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0028540 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages, during late pupal stages, in adult male stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0028540 expression level Developmental Stage   Expression Level embryo 00-02hr    102 embryo 02-04hr    155 embryo 04-06hr    57 embryo 06-08hr    37 embryo 08-10hr    59 embryo 10-12hr    225 embryo 12-14hr    390 embryo 14-16hr    491 embryo 16-18hr    761 embryo 18-20hr    1329 embryo 20-22hr    3410 embryo 22-24hr    3586 larva L1    1852 larva L2    1165 larva L3 12hr old    1177 larva L3 puffstage 1-2    793 larva L3 puffstage 3-6    1007 larva L3 puffstage 7-9    1334 white prepupae new    1136 white prepupae 12hr    1166 white prepupae 24hr    923 pupae 2d postWPP    1411 pupae 3d postWPP    1696 pupae 4d postWPP    1640 adult male 01day    2529 adult male 05day    2379 adult male 30day    2430 adult female 01day    1155 adult female 05day    611 adult female 30day    599 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  102 embryo 02-04hr  (155) embryo 04-06hr    57 embryo 06-08hr    37 embryo 08-10hr    59 embryo 10-12hr  (225) embryo 12-14hr  (390) embryo 14-16hr  (491) embryo 16-18hr  (761) embryo 18-20hr  (1329) embryo 20-22hr  (3410) embryo 22-24hr  (3586) larva L1  (1852) larva L2  (1165) larva L3 12hr old  (1177) larva L3 puffstage 1-2  (793) larva L3 puffstage 3-6  (1007) larva L3 puffstage 7-9  (1334) white prepupae new  (1136) white prepupae 12hr  (1166) white prepupae 24hr  (923) pupae 2d postWPP  (1411) pupae 3d postWPP  (1696) pupae 4d postWPP  (1640) adult male 01day  (2529) adult male 05day  (2379) adult male 30day  (2430) adult female 01day  (1155) adult female 05day  (611) adult female 30day  (599) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    102 embryo 02-04hr    155 embryo 04-06hr    57 embryo 06-08hr    37 embryo 08-10hr    59 embryo 10-12hr    225 embryo 12-14hr    390 embryo 14-16hr    491 embryo 16-18hr    761 embryo 18-20hr    1329 embryo 20-22hr  (3410) embryo 22-24hr  (3586) larva L1  (1852) larva L2    1165 larva L3 12hr old    1177 larva L3 puffstage 1-2    793 larva L3 puffstage 3-6    1007 larva L3 puffstage 7-9    1334 white prepupae new    1136 white prepupae 12hr    1166 white prepupae 24hr    923 pupae 2d postWPP  1411 pupae 3d postWPP  (1696) pupae 4d postWPP  (1640) adult male 01day  (2529) adult male 05day  (2379) adult male 30day  (2430) adult female 01day    1155 adult female 05day    611 adult female 30day    599 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    102 embryo 02-04hr    155 embryo 04-06hr    57 embryo 06-08hr    37 embryo 08-10hr    59 embryo 10-12hr    225 embryo 12-14hr    390 embryo 14-16hr    491 embryo 16-18hr    761 embryo 18-20hr    1329 embryo 20-22hr    3410 embryo 22-24hr    3586 larva L1    1852 larva L2    1165 larva L3 12hr old    1177 larva L3 puffstage 1-2    793 larva L3 puffstage 3-6    1007 larva L3 puffstage 7-9    1334 white prepupae new    1136 white prepupae 12hr    1166 white prepupae 24hr    923 pupae 2d postWPP    1411 pupae 3d postWPP    1696 pupae 4d postWPP    1640 adult male 01day    2529 adult male 05day    2379 adult male 30day    2430 adult female 01day    1155 adult female 05day    611 adult female 30day    599 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    102 embryo 02-04hr    155 embryo 04-06hr    57 embryo 06-08hr    37 embryo 08-10hr    59 embryo 10-12hr    225 embryo 12-14hr    390 embryo 14-16hr    491 embryo 16-18hr    761 embryo 18-20hr    1329 embryo 20-22hr    3410 embryo 22-24hr    3586 larva L1    1852 larva L2    1165 larva L3 12hr old    1177 larva L3 puffstage 1-2    793 larva L3 puffstage 3-6    1007 larva L3 puffstage 7-9    1334 white prepupae new    1136 white prepupae 12hr    1166 white prepupae 24hr    923 pupae 2d postWPP    1411 pupae 3d postWPP    1696 pupae 4d postWPP    1640 adult male 01day    2529 adult male 05day    2379 adult male 30day    2430 adult female 01day    1155 adult female 05day    611 adult female 30day    599 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0028540 expression level Developmental Stage   Expression Level embryo 00-02hr    102 embryo 02-04hr    155 embryo 04-06hr    57 embryo 06-08hr    37 embryo 08-10hr    59 embryo 10-12hr    225 embryo 12-14hr    390 embryo 14-16hr    491 embryo 16-18hr    761 embryo 18-20hr    1329 embryo 20-22hr    3410 embryo 22-24hr    3586 larva L1    1852 larva L2    1165 larva L3 12hr old    1177 larva L3 puffstage 1-2    793 larva L3 puffstage 3-6    1007 larva L3 puffstage 7-9    1334 white prepupae new    1136 white prepupae 12hr    1166 white prepupae 24hr    923 pupae 2d postWPP    1411 pupae 3d postWPP    1696 pupae 4d postWPP    1640 adult male 01day    2529 adult male 05day    2379 adult male 30day    2430 adult female 01day    1155 adult female 05day    611 adult female 30day    599 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  102 embryo 02-04hr  (155) embryo 04-06hr    57 embryo 06-08hr    37 embryo 08-10hr    59 embryo 10-12hr  (225) embryo 12-14hr  (390) embryo 14-16hr  (491) embryo 16-18hr  (761) embryo 18-20hr  (1329) embryo 20-22hr  (3410) embryo 22-24hr  (3586) larva L1  (1852) larva L2  (1165) larva L3 12hr old  (1177) larva L3 puffstage 1-2  (793) larva L3 puffstage 3-6  (1007) larva L3 puffstage 7-9  (1334) white prepupae new  (1136) white prepupae 12hr  (1166) white prepupae 24hr  (923) pupae 2d postWPP  (1411) pupae 3d postWPP  (1696) pupae 4d postWPP  (1640) adult male 01day  (2529) adult male 05day  (2379) adult male 30day  (2430) adult female 01day  (1155) adult female 05day  (611) adult female 30day  (599) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    102 embryo 02-04hr    155 embryo 04-06hr    57 embryo 06-08hr    37 embryo 08-10hr    59 embryo 10-12hr    225 embryo 12-14hr    390 embryo 14-16hr    491 embryo 16-18hr    761 embryo 18-20hr    1329 embryo 20-22hr  (3410) embryo 22-24hr  (3586) larva L1  1852 larva L2    1165 larva L3 12hr old    1177 larva L3 puffstage 1-2    793 larva L3 puffstage 3-6    1007 larva L3 puffstage 7-9    1334 white prepupae new    1136 white prepupae 12hr    1166 white prepupae 24hr    923 pupae 2d postWPP  1411 pupae 3d postWPP  1696 pupae 4d postWPP  1640 adult male 01day  (2529) adult male 05day  2379 adult male 30day  2430 adult female 01day    1155 adult female 05day    611 adult female 30day    599 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    102 embryo 02-04hr    155 embryo 04-06hr    57 embryo 06-08hr    37 embryo 08-10hr    59 embryo 10-12hr    225 embryo 12-14hr    390 embryo 14-16hr    491 embryo 16-18hr    761 embryo 18-20hr    1329 embryo 20-22hr    3410 embryo 22-24hr    3586 larva L1    1852 larva L2    1165 larva L3 12hr old    1177 larva L3 puffstage 1-2    793 larva L3 puffstage 3-6    1007 larva L3 puffstage 7-9    1334 white prepupae new    1136 white prepupae 12hr    1166 white prepupae 24hr    923 pupae 2d postWPP    1411 pupae 3d postWPP    1696 pupae 4d postWPP    1640 adult male 01day    2529 adult male 05day    2379 adult male 30day    2430 adult female 01day    1155 adult female 05day    611 adult female 30day    599 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    102 embryo 02-04hr    155 embryo 04-06hr    57 embryo 06-08hr    37 embryo 08-10hr    59 embryo 10-12hr    225 embryo 12-14hr    390 embryo 14-16hr    491 embryo 16-18hr    761 embryo 18-20hr    1329 embryo 20-22hr    3410 embryo 22-24hr    3586 larva L1    1852 larva L2    1165 larva L3 12hr old    1177 larva L3 puffstage 1-2    793 larva L3 puffstage 3-6    1007 larva L3 puffstage 7-9    1334 white prepupae new    1136 white prepupae 12hr    1166 white prepupae 24hr    923 pupae 2d postWPP    1411 pupae 3d postWPP    1696 pupae 4d postWPP    1640 adult male 01day    2529 adult male 05day    2379 adult male 30day    2430 adult female 01day    1155 adult female 05day    611 adult female 30day    599 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0028540    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0028540 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate levels. Expression at high levels in the following post-embryonic organs or tissues: adult Malpighian tubules, adult fat body, adult spermathecae. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, larval fat body, larval trachea, adult testis, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0028540 expression level Tissue   Expression Level Larval Central Nervous System    88.025 Larval Midgut    163.5 Larval Hindgut    139 Larval Malpighian Tubules    434.3 Larval Fat Body    303.1 Larval Salivary Gland    41.6 Larval Trachea    375.225 Larval Carcass    192.075 Adult Head    293.4 Adult Eye    134.025 Adult Brain    110.5 Adult Thoracic-Abdominal Ganglion    213.7 Adult Crop    299.6 Adult Midgut    408.5 Adult Hindgut    137.5 Adult Malpighian Tubules    2232.9 Adult Fat Body    709.2 Adult Salivary Gland    92.1 Adult Heart    465.8 Adult VirginFemale Spermatheca    1462.2 Adult InseminatedFemale Spermatheca    983.7 Adult Ovary    59 Adult Testis    431.9 Adult Male Accessory Gland    21.7 Adult Carcass    425.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    88.025 Larval Midgut    163.5 Larval Hindgut    139 Larval Malpighian Tubules    434.3 Larval Fat Body    303.1 Larval Salivary Gland    41.6 Larval Trachea    375.225 Larval Carcass    192.075 Adult Head    293.4 Adult Eye    134.025 Adult Brain    110.5 Adult Thoracic-Abdominal Ganglion    213.7 Adult Crop    299.6 Adult Midgut    408.5 Adult Hindgut    137.5 Adult Malpighian Tubules  (2232.9) Adult Fat Body  (709.2) Adult Salivary Gland    92.1 Adult Heart    465.8 Adult VirginFemale Spermatheca  (1462.2) Adult InseminatedFemale Spermatheca  (983.7) Adult Ovary    59 Adult Testis    431.9 Adult Male Accessory Gland    21.7 Adult Carcass    425.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    88.025 Larval Midgut    163.5 Larval Hindgut    139 Larval Malpighian Tubules    434.3 Larval Fat Body    303.1 Larval Salivary Gland    41.6 Larval Trachea    375.225 Larval Carcass    192.075 Adult Head    293.4 Adult Eye    134.025 Adult Brain    110.5 Adult Thoracic-Abdominal Ganglion    213.7 Adult Crop    299.6 Adult Midgut    408.5 Adult Hindgut    137.5 Adult Malpighian Tubules  (2232.9) Adult Fat Body    709.2 Adult Salivary Gland    92.1 Adult Heart    465.8 Adult VirginFemale Spermatheca  (1462.2) Adult InseminatedFemale Spermatheca    983.7 Adult Ovary    59 Adult Testis    431.9 Adult Male Accessory Gland    21.7 Adult Carcass    425.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    88.025 Larval Midgut    163.5 Larval Hindgut    139 Larval Malpighian Tubules    434.3 Larval Fat Body    303.1 Larval Salivary Gland    41.6 Larval Trachea    375.225 Larval Carcass    192.075 Adult Head    293.4 Adult Eye    134.025 Adult Brain    110.5 Adult Thoracic-Abdominal Ganglion    213.7 Adult Crop    299.6 Adult Midgut    408.5 Adult Hindgut    137.5 Adult Malpighian Tubules    2232.9 Adult Fat Body    709.2 Adult Salivary Gland    92.1 Adult Heart    465.8 Adult VirginFemale Spermatheca    1462.2 Adult InseminatedFemale Spermatheca    983.7 Adult Ovary    59 Adult Testis    431.9 Adult Male Accessory Gland    21.7 Adult Carcass    425.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0028540 expression level Tissue   Expression Level Larval Central Nervous System    88.025 Larval Midgut    163.5 Larval Hindgut    139 Larval Malpighian Tubules    434.3 Larval Fat Body    303.1 Larval Salivary Gland    41.6 Larval Trachea    375.225 Larval Carcass    192.075 Adult Head    293.4 Adult Eye    134.025 Adult Brain    110.5 Adult Thoracic-Abdominal Ganglion    213.7 Adult Crop    299.6 Adult Midgut    408.5 Adult Hindgut    137.5 Adult Malpighian Tubules    2232.9 Adult Fat Body    709.2 Adult Salivary Gland    92.1 Adult Heart    465.8 Adult VirginFemale Spermatheca    1462.2 Adult InseminatedFemale Spermatheca    983.7 Adult Ovary    59 Adult Testis    431.9 Adult Male Accessory Gland    21.7 Adult Carcass    425.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    88.025 Larval Midgut    163.5 Larval Hindgut    139 Larval Malpighian Tubules    434.3 Larval Fat Body    303.1 Larval Salivary Gland    41.6 Larval Trachea    375.225 Larval Carcass    192.075 Adult Head    293.4 Adult Eye    134.025 Adult Brain    110.5 Adult Thoracic-Abdominal Ganglion    213.7 Adult Crop    299.6 Adult Midgut    408.5 Adult Hindgut    137.5 Adult Malpighian Tubules  (2232.9) Adult Fat Body  709.2 Adult Salivary Gland    92.1 Adult Heart    465.8 Adult VirginFemale Spermatheca  (1462.2) Adult InseminatedFemale Spermatheca  (983.7) Adult Ovary    59 Adult Testis    431.9 Adult Male Accessory Gland    21.7 Adult Carcass    425.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    88.025 Larval Midgut    163.5 Larval Hindgut    139 Larval Malpighian Tubules    434.3 Larval Fat Body    303.1 Larval Salivary Gland    41.6 Larval Trachea    375.225 Larval Carcass    192.075 Adult Head    293.4 Adult Eye    134.025 Adult Brain    110.5 Adult Thoracic-Abdominal Ganglion    213.7 Adult Crop    299.6 Adult Midgut    408.5 Adult Hindgut    137.5 Adult Malpighian Tubules  (2232.9) Adult Fat Body    709.2 Adult Salivary Gland    92.1 Adult Heart    465.8 Adult VirginFemale Spermatheca  1462.2 Adult InseminatedFemale Spermatheca    983.7 Adult Ovary    59 Adult Testis    431.9 Adult Male Accessory Gland    21.7 Adult Carcass    425.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    88.025 Larval Midgut    163.5 Larval Hindgut    139 Larval Malpighian Tubules    434.3 Larval Fat Body    303.1 Larval Salivary Gland    41.6 Larval Trachea    375.225 Larval Carcass    192.075 Adult Head    293.4 Adult Eye    134.025 Adult Brain    110.5 Adult Thoracic-Abdominal Ganglion    213.7 Adult Crop    299.6 Adult Midgut    408.5 Adult Hindgut    137.5 Adult Malpighian Tubules    2232.9 Adult Fat Body    709.2 Adult Salivary Gland    92.1 Adult Heart    465.8 Adult VirginFemale Spermatheca    1462.2 Adult InseminatedFemale Spermatheca    983.7 Adult Ovary    59 Adult Testis    431.9 Adult Male Accessory Gland    21.7 Adult Carcass    425.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    293.4   NA  Eye    134.025   NA  Brain    110.5   88.025  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    213.7   NA  Crop    299.6   163.5  Midgut    408.5   139  Hindgut    137.5   434.3  Malpighian Tubules    2232.9   303.1  Fat Body    709.2   41.6  Salivary Gland    92.1   NA  Heart    465.8   375.225  Trachea    NA   NA  VirginFemale Spermatheca    1462.2   NA  InseminatedFemale Spermatheca    983.7   NA  Ovary    59   NA  Testis    431.9   NA  Male Accessory Gland    21.7   192.075  Carcass    425.1 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_10
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0028540 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9008-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG9008 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4αTub84B.PL CG9008Scer\UAS.cJa semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 CG9008GD4773 Other Phenotypes Allele body color defective, with Scer\GAL4pnr-MD237 CG9008GD4773 visible, with Scer\GAL4pnr-MD237 CG9008GD4773 Phenotype manifest in Allele mesothoracic tergum, with Scer\GAL4pnr-MD237 CG9008GD4773 microchaeta & mesothoracic tergum, with Scer\GAL4αTub84B.PL CG9008Scer\UAS.cJa trichogen cell, with Scer\GAL4pnr-MD237 CG9008GD4773
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of CG9008 Class Mutagen Stocks Known lesion CG90085-HA-3116 1 -- CG9008f00458 piggyBac transposase 1 -- CG9008f00470 piggyBac transposase 0 -- CG9008f00472 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG9008 Class Mutagen Stocks Known lesion CG9008GD4773 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG9008KK110184 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG9008dsRNA.Scer\UAS in vitro construct - regulatory fusion in vitro construct - RNAi 0 Yes CG9008Scer\UAS.cJa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel7058 (Ryder, 2004.4.26)
Partially disrupted in	Df(2L)Δ11 (Vrailas-Mortimer et al., 2011)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4773} NA P{KK110184} NA P{UAS-CG9008.J} NA P{UAS-CG9008.RNAi} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{RS5}CG90085-HA-3116 NA PBac{WH}CG9008f00458 NA PBac{WH}CG9008f00470 NA PBac{WH}CG9008f00472 NA
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
Golgi organization inferred from mutant phenotype (Kondylis et al., 2011) lipid particle organization inferred from mutant phenotype (Kondylis et al., 2011)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
carbohydrate binding inferred from electronic annotation with InterPro:IPR011013, InterPro:IPR014718 (FlyBase Curators et al., 2004-) isomerase activity inferred from electronic annotation with InterPro:IPR008183 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
carbohydrate metabolic process inferred from electronic annotation with InterPro:IPR008183, InterPro:IPR011013, InterPro:IPR014718 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG9008 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0028540 DroID - A comprehensive database of gene and protein interactions. • FBgn0028540 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34779
Orthologs
Genome-wide drosophilid orthologs	Dana\GF21693 Dere\GG10186 Dgri\GH10622 Dmoj\GI19758 Dper\GL21096 Dpse\GA21473 Dsec\GM15127 Dsim\GD22046 Dvir\GJ18093 Dwil\GK18199 Dyak\GE11470
Curated drosophilid orthologs	Dpse\GA21473
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL007315-PA Aedes aegypti (mosquito) AAEL015291-PA Aedes aegypti (mosquito) AGAP009039-PA Anopheles gambiae (mosquito) XP_001123335.1 Apis mellifera (honey bee) XP_001943587.1 Acyrthosiphon pisum (pea aphid) At3g61610.1 Arabidopsis thaliana (wall cress) 35052 Batrachochytrium dendrobatidis (chytrid fungus) 113534 Branchiostoma floridae (lancelet) BGIBMGA003610-PA Bombyx mori (silk worm) CAL0002587 Candida albicans (a form of yeast) CAGL0K03289g Candida glabrata (haploid yeast) ENSCINP00000021395 Ciona intestinalis (sea squirt) CMD040C Cyanidioschyzon merolae (red alga) cn11246 Cryptococcus neoformans (yeast-like fungus) CPIJ001900 Culex pipens (mosquito) 183481 Chlamidomonas reinhardtii (green alga) 80327 Chlamidomonas reinhardtii (green alga) ENSCSAVP00000014816 Ciona savignyi (sedentary tunicate) 152132 Capitella spl (polychaete worm) DDB0218007 Dictyostelium discoideum (amoeba) DEHA2E12892g Debaryomyces Hansenii (yeast) 306682 Daphnia pulex (daphnia) NP_416294.4 Escherichia coli K12 (bacteria) KLLA0C14300g Kluyveromyces lactis (yeast) 111836 Lottia gigantea (owl limpet) LmjF34.3380 Leishmania major (virus) 18889 Monocosta brevicollis (choanoflagellate) 134097 Nematostella vectensis (starlet anemone) XP_001600174.1 Nasonia vitripennis (wasp) LOC_Os01g46950.1 Oryza sativa (asian rice) 34931 Ostreococcus tauri (green alga) PHUM002943-PA Pediculus humanus (human body louse) 105048 Physcomitrella patens (moss) 77989 Phytophthora ramorum (sudden oak death pathogen) 86038 Phytophthora ramorum (sudden oak death pathogen) 137070 Phytophthora sojae (root rot pathogen) 737709 Populus trichocarpa (black cottonwood) 4762643 Sorghum bicolor (sorghum) YMR099C Saccharomyces cerevisiae (budding yeast) XP_001196154.1 Strongylocentrotus purpuratus (purple sea urchin) XP_001201242.1 Strongylocentrotus purpuratus (purple sea urchin) 54524 Trichoplax adhaerens (metazoa) XP_972052.2 Tribolium castaneum (red flour beetle) Tc00.1047053511003.190 Trypanosoma cruzi (parasitic trypanosome) 31636 Thalassiosira pseudonana (marine diatom) YALI0D07084g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB13153 NV17635 LH25096 ISCW006671 FBgn0229275 FBgn0220198 FBgn0205258 FBgn0193459 FBgn0170047 JGI_V11_306682 FBgn0081460 FBgn0158691 FBgn0142495 FBgn0118103 FBgn0102496 FBgn0098693 CPIJ001900 BGIBMGA003610 ACYPI000643 AGAP009039 AAEL015291 AAEL007315 PHUM380460 GLEAN_05179
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Harvard	- PBac{WH}CG9008f00458
Kyoto	125801 w1118; P{RS5}CG90085-HA-3116
VDRC	v107828 P{KK110184}VIE-260B v12808 w1118; P{GD4773}v12808 v12809 w1118; P{GD4773}v12809
Genomic Clones ( 1 )
	BACR30I21 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 34 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH14910
Other clones	DPiM_GH14910
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT03961 AT08043 AT11274 AT19249 HL03175 LP01278 LP04584 LP04871 LP04965 LP07112 RE10380 RE12683 RE54242 RE60914 RE62370 RE62970 RE66286
Other clones	71265 71747 bs21d02 EC31324 EC255871 EC259168 EK164046 EK173546 EK199262 EK253837 EP09536 EP11053 FGC019F12 RP004243384 RP004535207
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0028540 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34779
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: BG:DS00797.2 CG9008 (Guan, 1999.11)
Source for database merge of
Additional comments
Other Comments
	Area matching Drosophila EST AA697797. (Davies, 2001.3.15)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_135826 NM_165055 RefSeq (Proteins) • NP_609670 NP_723835 DDBJ / EMBL / GenBank • AA697797 AAF44811 AAF53325 AAF53325.1 AAL25344 AAN10844.1 AAN10845 AAN10845.2 AE003407 AI238795 AI513328 AI946139 AX094001 AY060305 CZ482929 CZ482930 CZ482941 CZ482943 Entrez Gene - A searchable database of RefSeq genes. • 34779 UniProtKB/TrEMBL • Q8IP67 Q9V3D1
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Aldose 1-epimerase (IPR008183) Glycoside hydrolase-type carbohydrate-binding (IPR011013) Glycoside hydrolase-type carbohydrate-binding, subgroup (IPR014718)
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0028540 DroID - A comprehensive database of gene and protein interactions. • FBgn0028540 DRSC - Results from RNAi screens. • FBgn0028540 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0028540 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9008-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0028540 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34779 InParanoid A subset of ortholog calls from InParanoid. • AAEL007315-PA Aedes aegypti (mosquito) AAEL015291-PA Aedes aegypti (mosquito) AGAP009039-PA Anopheles gambiae (mosquito) XP_001123335.1 Apis mellifera (honey bee) XP_001943587.1 Acyrthosiphon pisum (pea aphid) At3g61610.1 Arabidopsis thaliana (wall cress) 35052 Batrachochytrium dendrobatidis (chytrid fungus) 113534 Branchiostoma floridae (lancelet) BGIBMGA003610-PA Bombyx mori (silk worm) CAL0002587 Candida albicans (a form of yeast) CAGL0K03289g Candida glabrata (haploid yeast) ENSCINP00000021395 Ciona intestinalis (sea squirt) CMD040C Cyanidioschyzon merolae (red alga) cn11246 Cryptococcus neoformans (yeast-like fungus) CPIJ001900 Culex pipens (mosquito) 183481 Chlamidomonas reinhardtii (green alga) 80327 Chlamidomonas reinhardtii (green alga) ENSCSAVP00000014816 Ciona savignyi (sedentary tunicate) 152132 Capitella spl (polychaete worm) DDB0218007 Dictyostelium discoideum (amoeba) DEHA2E12892g Debaryomyces Hansenii (yeast) 306682 Daphnia pulex (daphnia) NP_416294.4 Escherichia coli K12 (bacteria) KLLA0C14300g Kluyveromyces lactis (yeast) 111836 Lottia gigantea (owl limpet) LmjF34.3380 Leishmania major (virus) 18889 Monocosta brevicollis (choanoflagellate) 134097 Nematostella vectensis (starlet anemone) XP_001600174.1 Nasonia vitripennis (wasp) LOC_Os01g46950.1 Oryza sativa (asian rice) 34931 Ostreococcus tauri (green alga) PHUM002943-PA Pediculus humanus (human body louse) 105048 Physcomitrella patens (moss) 77989 Phytophthora ramorum (sudden oak death pathogen) 86038 Phytophthora ramorum (sudden oak death pathogen) 137070 Phytophthora sojae (root rot pathogen) 737709 Populus trichocarpa (black cottonwood) 4762643 Sorghum bicolor (sorghum) YMR099C Saccharomyces cerevisiae (budding yeast) XP_001196154.1 Strongylocentrotus purpuratus (purple sea urchin) XP_001201242.1 Strongylocentrotus purpuratus (purple sea urchin) 54524 Trichoplax adhaerens (metazoa) XP_972052.2 Tribolium castaneum (red flour beetle) Tc00.1047053511003.190 Trypanosoma cruzi (parasitic trypanosome) 31636 Thalassiosira pseudonana (marine diatom) YALI0D07084g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34779 modMine - Data generated by the modENCODE project. • FBgn0028540 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB13153 NV17635 LH25096 ISCW006671 FBgn0229275 FBgn0220198 FBgn0205258 FBgn0193459 FBgn0170047 JGI_V11_306682 FBgn0081460 FBgn0158691 FBgn0142495 FBgn0118103 FBgn0102496 FBgn0098693 CPIJ001900 BGIBMGA003610 ACYPI000643 AGAP009039 AAEL015291 AAEL007315 PHUM380460 GLEAN_05179
Synonyms & Secondary IDs ( 2 )
Reported As
Symbol Synonym	BG:DS00797.2 (Butler et al., 2003, Ashburner et al., 1999.10.12, Ashburner et al., 1999, Ashburner et al., 1999, Davies et al., 2001, Jacobsen et al., 2006) CG9008 (Moorman et al., 2006, Jacobsen et al., 2006, Nechaev et al., 2010, Gilchrist et al., 2008, Keleman et al., 2009.8.5, Fujikawa et al., 2009, Muse et al., 2007, Kondylis et al., 2011, Cherbas et al., 2011)
Name Synonym
Secondary FlyBase IDs
	FBgn0027905 FBpp0080153 FBpp0080154 FBpp0080155 FBtr0080576 FBtr0080577 FBtr0080578
References ( 29 )
Generate a list of	All references relating to this gene ( 29 )
List References by type	Research paper  ( 11 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 6 ) FlyBase analysis  ( 1 ) Patent  ( 1 ) Curated genome annotation  ( 1 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 3 )
Recent research papers ( 5 )
	Cherbas et al., 2011, Genome Res. 21(2): 301--314 The transcriptional diversity of 25 Drosophila cell lines. [FBrf0213077] Kondylis et al., 2011, PLoS ONE 6(2): e17173 Identification of ER Proteins Involved in the Functional Organisation of the Early Secretory Pathway in Drosophila Cells by a Targeted RNAi Screen. [FBrf0213167] Vrailas-Mortimer et al., 2011, Dev. Cell 21(4): 783--795 A Muscle-Specific p38 MAPK/Mef2/MnSOD Pathway Regulates Stress, Motor Function, and Life Span in Drosophila. [FBrf0216446] Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Nechaev et al., 2010, Science 327(5963): 335--338 Global analysis of short RNAs reveals widespread promoter-proximal stalling and arrest of Pol II in Drosophila. [FBrf0209722] Show all research papers ...