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Gene Dmel\VhaPPA1-1

General Information
Symbol	Dmel\VhaPPA1-1	Species	D. melanogaster
Name	Vacuolar H+ ATPase subunit PPA1-1	Annotation symbol	CG7007
Feature type	protein_coding_gene	FlyBase ID	FBgn0028662
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	88D6-88D6	Sequence location	3R:10,728,048..10,729,796 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Vacuolar H+ ATPase subunit PPA1-1 is referred to in FlyBase by the symbol Dmel\VhaPPA1-1 (CG7007, FBgn0028662). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: hydrogen-exporting ATPase activity, phosphorylative mechanism. There is experimental evidence that it is involved in the biological process: mitotic spindle organization. 5 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: ATPase, F0/V0 complex, subunit C; ATPase, V0 complex, proteolipid subunit C. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. Comments on Affy2 ProbeSet: ProbeSet 1637024_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of VhaPPA1-1. Gene sequence location is 3R:10728048..10729796.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	Sequence features HFA16170 BKN28859
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 88D6-88D6   Limits computationally determined from genome sequence between P{EP}CG33967EP666 and P{lacW}Hsc70-4L3929
Experimentally Determined Cytological Location
Cytogenetic map Notes References 88D-88E     (Dow, 1999)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\VhaPPA1-1 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) VhaPPA1-1-RA FBtr0083005  NM_143753   1369   212 VhaPPA1-1-RB FBtr0308030     1365   212
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein VhaPPA1-1-PA   FBpp0082464   22.0   212   8.83     NP_652010   AAF55117 VhaPPA1-1-PB   FBpp0300391   22.0   212   8.83
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • ATPase, V0 complex, proteolipid subunit C (IPR000245) ATPase, F0/V0 complex, subunit C (IPR002379)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA539661   AA696100   AA951453   AE014297 AAF55117   AI061887   AI063607   AI135210   AI259875   AI295462   AI401916   AI404599   AI404791   AI512965   AI514107   AI517111   AI532829   AI945023   AX094232   AY060235 AAL25274   BE662234   BF488018   BG636139   BG641081   BI163718   BI166767   BI168322   BI169301   BI173162   BI173623   BI214173   BI214836   BI215440   BI215465   BI227470   BI229076   BI230384   BI231979   BI232673   BI233272   BI238321   BI351684   BI356132   BI356165   BI356785   BI361556   BI362833   BI370144   BI371612   BI565496   BI577180   BI579115   BI589802   BI593033   BI607216   BI611620   BI621087   BI621747   BI625612   BI632646   BI632751   BI637774   BI637925   BI638990   BI639835   BI641656   BP544791   BP544792   BP551651   BP551757   BP554650   BP554651   BP555973   BP555974   BX005947   BX013003   BX013853   BX020361   BX026279   BX043159   BX062528   BX067695   BX070497   CK660041   CK661461   CK662003   CK662209   CO154975   CO189028   CO269504   CO276387   CO280069   CO280509   CO291683   CO295713   CO329640   CO341398   CR937158   CR937329   CR937556   CR937663   CR937723   CZ480996   EC056493   EC057903   EC073246   EC074981   EC086457   EC204834   EC220563   EC233806   EC243419   EC258275   EC262878   EV589635   EV590465   EV595417   EV595736   EV597584   GH749342   GH750220   GH750560   GH750611   GH754062   GH755493   GH756249   GH756317   GH756671   GH757370   GH757465   GH757965   GH773308   GH775701   GH777901   GH778743   GH780936   GH781333   GH786526   GH793047   GH795445   GH795654   GH802195   GH802343   GH807420   GH807974   GH807997   GH808851   GH810462   GH811823   GH813030   GH813442   GH815457   GH829597   GH838946   GH843551   GH846200   GH850288   GH850795   GH851069   GH853101   GH854039   GH856609   GH860720   GH860980   GH861237   GH862729   GH863200   GH863524   GH864363   GH866143   GH866853   GH867608   GH869755   GH870618   GH870636   GH870860   GH878522   GH878651   GH879848   GH879876   GH880846   GH884206   GH884293   GH884463   GH887261   GH891045   GH892550   GH892682   GH892849   GH893018   GH894495   GH897081   GH899868   GH902667   GH903657   GH906090   GH909270   GH915092   GH915147   GH915879   GH916983   GH917135   GH917634   GH919562   GH919886   GH920633   GH920688   GH922435   GH925907   GH928866   GH929238   GH931330   GH931331   GH932302   GH934470   GH935267   GH935444
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VFE3
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0028662    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0028662 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0028662 expression level Developmental Stage   Expression Level embryo 00-02hr    13377 embryo 02-04hr    9057 embryo 04-06hr    8603 embryo 06-08hr    9644 embryo 08-10hr    9941 embryo 10-12hr    10442 embryo 12-14hr    8176 embryo 14-16hr    12876 embryo 16-18hr    16000 embryo 18-20hr    22730 embryo 20-22hr    35340 embryo 22-24hr    32552 larva L1    38442 larva L2    28629 larva L3 12hr old    26725 larva L3 puffstage 1-2    20055 larva L3 puffstage 3-6    15241 larva L3 puffstage 7-9    13041 white prepupae new    7851 white prepupae 12hr    9438 white prepupae 24hr    6196 pupae 2d postWPP    7803 pupae 3d postWPP    8287 pupae 4d postWPP    16692 adult male 01day    13070 adult male 05day    12601 adult male 30day    13755 adult female 01day    17946 adult female 05day    14255 adult female 30day    14773 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (13377) embryo 02-04hr  (9057) embryo 04-06hr  (8603) embryo 06-08hr  (9644) embryo 08-10hr  (9941) embryo 10-12hr  (10442) embryo 12-14hr  (8176) embryo 14-16hr  (12876) embryo 16-18hr  (16000) embryo 18-20hr  (22730) embryo 20-22hr  (35340) embryo 22-24hr  (32552) larva L1  (38442) larva L2  (28629) larva L3 12hr old  (26725) larva L3 puffstage 1-2  (20055) larva L3 puffstage 3-6  (15241) larva L3 puffstage 7-9  (13041) white prepupae new  (7851) white prepupae 12hr  (9438) white prepupae 24hr  (6196) pupae 2d postWPP  (7803) pupae 3d postWPP  (8287) pupae 4d postWPP  (16692) adult male 01day  (13070) adult male 05day  (12601) adult male 30day  (13755) adult female 01day  (17946) adult female 05day  (14255) adult female 30day  (14773) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (13377) embryo 02-04hr  (9057) embryo 04-06hr  (8603) embryo 06-08hr  (9644) embryo 08-10hr  (9941) embryo 10-12hr  (10442) embryo 12-14hr  (8176) embryo 14-16hr  (12876) embryo 16-18hr  (16000) embryo 18-20hr  (22730) embryo 20-22hr  (35340) embryo 22-24hr  (32552) larva L1  (38442) larva L2  (28629) larva L3 12hr old  (26725) larva L3 puffstage 1-2  (20055) larva L3 puffstage 3-6  (15241) larva L3 puffstage 7-9  (13041) white prepupae new  (7851) white prepupae 12hr  (9438) white prepupae 24hr  (6196) pupae 2d postWPP  (7803) pupae 3d postWPP  (8287) pupae 4d postWPP  (16692) adult male 01day  (13070) adult male 05day  (12601) adult male 30day  (13755) adult female 01day  (17946) adult female 05day  (14255) adult female 30day  (14773) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (13377) embryo 02-04hr    9057 embryo 04-06hr    8603 embryo 06-08hr    9644 embryo 08-10hr    9941 embryo 10-12hr  10442 embryo 12-14hr    8176 embryo 14-16hr  (12876) embryo 16-18hr  (16000) embryo 18-20hr  (22730) embryo 20-22hr  (35340) embryo 22-24hr  (32552) larva L1  (38442) larva L2  (28629) larva L3 12hr old  (26725) larva L3 puffstage 1-2  (20055) larva L3 puffstage 3-6  (15241) larva L3 puffstage 7-9  (13041) white prepupae new    7851 white prepupae 12hr    9438 white prepupae 24hr    6196 pupae 2d postWPP    7803 pupae 3d postWPP    8287 pupae 4d postWPP  (16692) adult male 01day  (13070) adult male 05day  (12601) adult male 30day  (13755) adult female 01day  (17946) adult female 05day  (14255) adult female 30day  (14773) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    13377 embryo 02-04hr    9057 embryo 04-06hr    8603 embryo 06-08hr    9644 embryo 08-10hr    9941 embryo 10-12hr    10442 embryo 12-14hr    8176 embryo 14-16hr    12876 embryo 16-18hr    16000 embryo 18-20hr    22730 embryo 20-22hr    35340 embryo 22-24hr    32552 larva L1    38442 larva L2    28629 larva L3 12hr old    26725 larva L3 puffstage 1-2    20055 larva L3 puffstage 3-6    15241 larva L3 puffstage 7-9    13041 white prepupae new    7851 white prepupae 12hr    9438 white prepupae 24hr    6196 pupae 2d postWPP    7803 pupae 3d postWPP    8287 pupae 4d postWPP    16692 adult male 01day    13070 adult male 05day    12601 adult male 30day    13755 adult female 01day    17946 adult female 05day    14255 adult female 30day    14773 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0028662 expression level Developmental Stage   Expression Level embryo 00-02hr    13377 embryo 02-04hr    9057 embryo 04-06hr    8603 embryo 06-08hr    9644 embryo 08-10hr    9941 embryo 10-12hr    10442 embryo 12-14hr    8176 embryo 14-16hr    12876 embryo 16-18hr    16000 embryo 18-20hr    22730 embryo 20-22hr    35340 embryo 22-24hr    32552 larva L1    38442 larva L2    28629 larva L3 12hr old    26725 larva L3 puffstage 1-2    20055 larva L3 puffstage 3-6    15241 larva L3 puffstage 7-9    13041 white prepupae new    7851 white prepupae 12hr    9438 white prepupae 24hr    6196 pupae 2d postWPP    7803 pupae 3d postWPP    8287 pupae 4d postWPP    16692 adult male 01day    13070 adult male 05day    12601 adult male 30day    13755 adult female 01day    17946 adult female 05day    14255 adult female 30day    14773 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (13377) embryo 02-04hr  (9057) embryo 04-06hr  (8603) embryo 06-08hr  (9644) embryo 08-10hr  (9941) embryo 10-12hr  (10442) embryo 12-14hr  (8176) embryo 14-16hr  (12876) embryo 16-18hr  (16000) embryo 18-20hr  (22730) embryo 20-22hr  (35340) embryo 22-24hr  (32552) larva L1  (38442) larva L2  (28629) larva L3 12hr old  (26725) larva L3 puffstage 1-2  (20055) larva L3 puffstage 3-6  (15241) larva L3 puffstage 7-9  (13041) white prepupae new  (7851) white prepupae 12hr  (9438) white prepupae 24hr  (6196) pupae 2d postWPP  (7803) pupae 3d postWPP  (8287) pupae 4d postWPP  (16692) adult male 01day  (13070) adult male 05day  (12601) adult male 30day  (13755) adult female 01day  (17946) adult female 05day  (14255) adult female 30day  (14773) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (13377) embryo 02-04hr  (9057) embryo 04-06hr  (8603) embryo 06-08hr  (9644) embryo 08-10hr  (9941) embryo 10-12hr  (10442) embryo 12-14hr  (8176) embryo 14-16hr  (12876) embryo 16-18hr  (16000) embryo 18-20hr  (22730) embryo 20-22hr  (35340) embryo 22-24hr  (32552) larva L1  (38442) larva L2  (28629) larva L3 12hr old  (26725) larva L3 puffstage 1-2  (20055) larva L3 puffstage 3-6  (15241) larva L3 puffstage 7-9  (13041) white prepupae new  (7851) white prepupae 12hr  (9438) white prepupae 24hr  (6196) pupae 2d postWPP  (7803) pupae 3d postWPP  (8287) pupae 4d postWPP  (16692) adult male 01day  (13070) adult male 05day  (12601) adult male 30day  (13755) adult female 01day  (17946) adult female 05day  (14255) adult female 30day  (14773) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  13377 embryo 02-04hr    9057 embryo 04-06hr    8603 embryo 06-08hr    9644 embryo 08-10hr    9941 embryo 10-12hr  10442 embryo 12-14hr    8176 embryo 14-16hr  12876 embryo 16-18hr  16000 embryo 18-20hr  (22730) embryo 20-22hr  (35340) embryo 22-24hr  (32552) larva L1  (38442) larva L2  (28629) larva L3 12hr old  (26725) larva L3 puffstage 1-2  20055 larva L3 puffstage 3-6  15241 larva L3 puffstage 7-9  13041 white prepupae new    7851 white prepupae 12hr    9438 white prepupae 24hr    6196 pupae 2d postWPP    7803 pupae 3d postWPP    8287 pupae 4d postWPP  16692 adult male 01day  13070 adult male 05day  12601 adult male 30day  13755 adult female 01day  17946 adult female 05day  14255 adult female 30day  14773 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    13377 embryo 02-04hr    9057 embryo 04-06hr    8603 embryo 06-08hr    9644 embryo 08-10hr    9941 embryo 10-12hr    10442 embryo 12-14hr    8176 embryo 14-16hr    12876 embryo 16-18hr    16000 embryo 18-20hr    22730 embryo 20-22hr    35340 embryo 22-24hr    32552 larva L1    38442 larva L2    28629 larva L3 12hr old    26725 larva L3 puffstage 1-2    20055 larva L3 puffstage 3-6    15241 larva L3 puffstage 7-9    13041 white prepupae new    7851 white prepupae 12hr    9438 white prepupae 24hr    6196 pupae 2d postWPP    7803 pupae 3d postWPP    8287 pupae 4d postWPP    16692 adult male 01day    13070 adult male 05day    12601 adult male 30day    13755 adult female 01day    17946 adult female 05day    14255 adult female 30day    14773 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0028662    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0028662 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0028662 expression level Tissue   Expression Level Larval Central Nervous System    997.775 Larval Midgut    3796.5 Larval Hindgut    4511.2 Larval Malpighian Tubules    4187 Larval Fat Body    1157.3 Larval Salivary Gland    3139.4 Larval Trachea    2042.75 Larval Carcass    2148.05 Adult Head    1132.3 Adult Eye    1415 Adult Brain    1603.7 Adult Thoracic-Abdominal Ganglion    1639.3 Adult Crop    1107.3 Adult Midgut    3673.4 Adult Hindgut    4577.9 Adult Malpighian Tubules    5532.7 Adult Fat Body    542.6 Adult Salivary Gland    8288.5 Adult Heart    1124.775 Adult VirginFemale Spermatheca    768.4 Adult InseminatedFemale Spermatheca    859.9 Adult Ovary    1128.2 Adult Testis    493 Adult Male Accessory Gland    826.1 Adult Carcass    809.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (997.775) Larval Midgut  (3796.5) Larval Hindgut  (4511.2) Larval Malpighian Tubules  (4187) Larval Fat Body  (1157.3) Larval Salivary Gland  (3139.4) Larval Trachea  (2042.75) Larval Carcass  (2148.05) Adult Head  (1132.3) Adult Eye  (1415) Adult Brain  (1603.7) Adult Thoracic-Abdominal Ganglion  (1639.3) Adult Crop  (1107.3) Adult Midgut  (3673.4) Adult Hindgut  (4577.9) Adult Malpighian Tubules  (5532.7) Adult Fat Body  (542.6) Adult Salivary Gland  (8288.5) Adult Heart  (1124.775) Adult VirginFemale Spermatheca  (768.4) Adult InseminatedFemale Spermatheca  (859.9) Adult Ovary  (1128.2) Adult Testis    493 Adult Male Accessory Gland  (826.1) Adult Carcass  (809.7) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    997.775 Larval Midgut  (3796.5) Larval Hindgut  (4511.2) Larval Malpighian Tubules  (4187) Larval Fat Body  (1157.3) Larval Salivary Gland  (3139.4) Larval Trachea  (2042.75) Larval Carcass  (2148.05) Adult Head  (1132.3) Adult Eye  (1415) Adult Brain  (1603.7) Adult Thoracic-Abdominal Ganglion  (1639.3) Adult Crop  (1107.3) Adult Midgut  (3673.4) Adult Hindgut  (4577.9) Adult Malpighian Tubules  (5532.7) Adult Fat Body    542.6 Adult Salivary Gland  (8288.5) Adult Heart  (1124.775) Adult VirginFemale Spermatheca    768.4 Adult InseminatedFemale Spermatheca    859.9 Adult Ovary  (1128.2) Adult Testis    493 Adult Male Accessory Gland    826.1 Adult Carcass    809.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    997.775 Larval Midgut    3796.5 Larval Hindgut    4511.2 Larval Malpighian Tubules    4187 Larval Fat Body    1157.3 Larval Salivary Gland    3139.4 Larval Trachea    2042.75 Larval Carcass    2148.05 Adult Head    1132.3 Adult Eye    1415 Adult Brain    1603.7 Adult Thoracic-Abdominal Ganglion    1639.3 Adult Crop    1107.3 Adult Midgut    3673.4 Adult Hindgut    4577.9 Adult Malpighian Tubules    5532.7 Adult Fat Body    542.6 Adult Salivary Gland    8288.5 Adult Heart    1124.775 Adult VirginFemale Spermatheca    768.4 Adult InseminatedFemale Spermatheca    859.9 Adult Ovary    1128.2 Adult Testis    493 Adult Male Accessory Gland    826.1 Adult Carcass    809.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0028662 expression level Tissue   Expression Level Larval Central Nervous System    997.775 Larval Midgut    3796.5 Larval Hindgut    4511.2 Larval Malpighian Tubules    4187 Larval Fat Body    1157.3 Larval Salivary Gland    3139.4 Larval Trachea    2042.75 Larval Carcass    2148.05 Adult Head    1132.3 Adult Eye    1415 Adult Brain    1603.7 Adult Thoracic-Abdominal Ganglion    1639.3 Adult Crop    1107.3 Adult Midgut    3673.4 Adult Hindgut    4577.9 Adult Malpighian Tubules    5532.7 Adult Fat Body    542.6 Adult Salivary Gland    8288.5 Adult Heart    1124.775 Adult VirginFemale Spermatheca    768.4 Adult InseminatedFemale Spermatheca    859.9 Adult Ovary    1128.2 Adult Testis    493 Adult Male Accessory Gland    826.1 Adult Carcass    809.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (997.775) Larval Midgut  (3796.5) Larval Hindgut  (4511.2) Larval Malpighian Tubules  (4187) Larval Fat Body  (1157.3) Larval Salivary Gland  (3139.4) Larval Trachea  (2042.75) Larval Carcass  (2148.05) Adult Head  (1132.3) Adult Eye  (1415) Adult Brain  (1603.7) Adult Thoracic-Abdominal Ganglion  (1639.3) Adult Crop  (1107.3) Adult Midgut  (3673.4) Adult Hindgut  (4577.9) Adult Malpighian Tubules  (5532.7) Adult Fat Body  542.6 Adult Salivary Gland  (8288.5) Adult Heart  (1124.775) Adult VirginFemale Spermatheca  768.4 Adult InseminatedFemale Spermatheca  (859.9) Adult Ovary  (1128.2) Adult Testis    493 Adult Male Accessory Gland  (826.1) Adult Carcass  809.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    997.775 Larval Midgut  (3796.5) Larval Hindgut  (4511.2) Larval Malpighian Tubules  (4187) Larval Fat Body  1157.3 Larval Salivary Gland  (3139.4) Larval Trachea  (2042.75) Larval Carcass  (2148.05) Adult Head  1132.3 Adult Eye  1415 Adult Brain  1603.7 Adult Thoracic-Abdominal Ganglion  1639.3 Adult Crop  1107.3 Adult Midgut  (3673.4) Adult Hindgut  (4577.9) Adult Malpighian Tubules  (5532.7) Adult Fat Body    542.6 Adult Salivary Gland  (8288.5) Adult Heart  1124.775 Adult VirginFemale Spermatheca    768.4 Adult InseminatedFemale Spermatheca    859.9 Adult Ovary  1128.2 Adult Testis    493 Adult Male Accessory Gland    826.1 Adult Carcass    809.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    997.775 Larval Midgut    3796.5 Larval Hindgut    4511.2 Larval Malpighian Tubules    4187 Larval Fat Body    1157.3 Larval Salivary Gland    3139.4 Larval Trachea    2042.75 Larval Carcass    2148.05 Adult Head    1132.3 Adult Eye    1415 Adult Brain    1603.7 Adult Thoracic-Abdominal Ganglion    1639.3 Adult Crop    1107.3 Adult Midgut    3673.4 Adult Hindgut    4577.9 Adult Malpighian Tubules    5532.7 Adult Fat Body    542.6 Adult Salivary Gland    8288.5 Adult Heart    1124.775 Adult VirginFemale Spermatheca    768.4 Adult InseminatedFemale Spermatheca    859.9 Adult Ovary    1128.2 Adult Testis    493 Adult Male Accessory Gland    826.1 Adult Carcass    809.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    1132.3   NA  Eye    1415   NA  Brain    1603.7   997.775  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    1639.3   NA  Crop    1107.3   3796.5  Midgut    3673.4   4511.2  Hindgut    4577.9   4187  Malpighian Tubules    5532.7   1157.3  Fat Body    542.6   3139.4  Salivary Gland    8288.5   NA  Heart    1124.775   2042.75  Trachea    NA   NA  VirginFemale Spermatheca    768.4   NA  InseminatedFemale Spermatheca    859.9   NA  Ovary    1128.2   NA  Testis    493   NA  Male Accessory Gland    826.1   2148.05  Carcass    809.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_20
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0028662 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7007-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal VhaPPA1-1CB02209 lethal, with Scer\GAL4pnr-MD237 VhaPPA1-1GD2991 lethal | pupal stage VhaPPA1-1EP3504 lethal | pupal stage, with Scer\GAL4pnr-MD237 VhaPPA1-1GD16478 semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 VhaPPA1-1GD16478 Other Phenotypes Allele body color defective, with Scer\GAL4pnr-MD237 VhaPPA1-1GD16478 visible, with Scer\GAL4pnr-MD237 VhaPPA1-1GD16478 Phenotype manifest in Allele chaeta | supernumerary, with Scer\GAL4pnr-MD237 VhaPPA1-1GD16478 mesothoracic tergum, with Scer\GAL4pnr-MD237 VhaPPA1-1GD16478
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of VhaPPA1-1 Class Mutagen Stocks Known lesion VhaPPA1-1e03223 piggyBac transposase 1 -- VhaPPA1-1EP3504 P-element activity 1 -- VhaPPA1-1CB02209 P-element activity 0 Yes
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of VhaPPA1-1 Class Mutagen Stocks Known lesion VhaPPA1-1GD16478 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes VhaPPA1-1GD2991 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)Exel6172 (Ryder, 2004.4.26) Df(3R)Exel6275 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD2991} NA P{GD16478} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}VhaPPA1-1EP3504 NA miscellaneous insertions P{PTT-GB}VhaPPA1-1CB02209 NA PBac{RB}VhaPPA1-1e03223 NA
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
mitotic spindle organization inferred from mutant phenotype (Goshima et al., 2007)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
hydrogen-exporting ATPase activity, phosphorylative mechanism inferred from sequence or structural similarity with Saccharomyces PPA1 (Dow, 1999, FlyBase, 1992-)
Biological Process
CV term Evidence References
ATP hydrolysis coupled proton transport inferred from electronic annotation with InterPro:IPR000245, InterPro:IPR002379 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
vacuolar proton-transporting V-type ATPase, V0 domain inferred from sequence or structural similarity with Saccharomyces PPA1 (Dow, 1999, FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions VhaPPA1-1 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 69537 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0028662 DroID - A comprehensive database of gene and protein interactions. • FBgn0028662 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 45247
Orthologs
Genome-wide drosophilid orthologs	Dana\GF17169 Dere\GG20968 Dgri\GH19517 Dmoj\GI22994 Dper\GL21698 Dpse\GA20025 Dsec\GM25814 Dsim\GD20390 Dvir\GJ24692 Dwil\GK11008 Dyak\GE26419
Curated drosophilid orthologs	Dpse\GA20025
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL012113-PA Aedes aegypti (mosquito) AGAP009334-PA Anopheles gambiae (mosquito) XP_392599.1 Apis mellifera (honey bee) XP_001951663.1 Acyrthosiphon pisum (pea aphid) At4g32530.1 Arabidopsis thaliana (wall cress) 7923 Batrachochytrium dendrobatidis (chytrid fungus) 114064 Branchiostoma floridae (lancelet) 88862 Branchiostoma floridae (lancelet) BGIBMGA000231-PA Bombyx mori (silk worm) ENSBTAP00000025144 Bos taurus (bovine) CAL0006331 Candida albicans (a form of yeast) CBP00885 Caenorhabditis briggsae (nematode) CE03595 Caenorhabditis elegans (worm) ENSCAFP00000007255 Canis familiaris (dog) CAGL0J00627g Candida glabrata (haploid yeast) Chro.80551 Cryptosporidium hominis (obligate parasite) ENSCINP00000017036 Ciona intestinalis (sea squirt) CMS332C Cyanidioschyzon merolae (red alga) cn10110 Cryptococcus neoformans (yeast-like fungus) cgd8_4790 Cryptosporidium parvum (protozoan parasite) CPIJ004794 Culex pipens (mosquito) ENSCPOP00000006767 Cavia porcellus (guinea pig) 120047 Chlamidomonas reinhardtii (green alga) RP29641 Caenorhabditis remanei (nematode) ENSCSAVP00000007323 Ciona savignyi (sedentary tunicate) 155226 Capitella spl (polychaete worm) DDB0167520 Dictyostelium discoideum (amoeba) DEHA2E16368g Debaryomyces Hansenii (yeast) 308098 Daphnia pulex (daphnia) ENSDARP00000045010 Danio rerio (zebra fish) ENSECAP00000021815 Equus caballus (horse) XP_649565 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000022738 Gymnopilus aculeatus (mushroom) ENSGALP00000016395 Gallus gallus (chicken) GL50803_15598 Giardia lamblia (flagellated protozoan) 186197 Hypsipyla robusta (cedar shoot borer) ENSP00000236067 Homo sapiens (human) ISCW018464-PA Ixodes scapularis (deer tick) KLLA0E11529g Kluyveromyces lactis (yeast) 223715 Lottia gigantea (owl limpet) LmjF30.3660 Leishmania major (virus) 17271 Monocosta brevicollis (choanoflagellate) ENSMODP00000003610 Monodelphis domestica (gray opossum) ENSMMUP00000040339 Macaca mulatta (rhesus monkey) ENSMUSP00000047682 Mus musculus (house mouse) 200737 Nematostella vectensis (starlet anemone) XP_001608002.1 Nasonia vitripennis (wasp) ENSOANP00000014335 Ornithorynchus anatinus (platypus) ENSORLP00000022196 Oryzias latipes (japanese killifish) LOC_Os01g42430.1 Oryza sativa (asian rice) 15314 Ostreococcus tauri (green alga) MAL13P1.271 Plasmodium falciparum (protozoal parasite) PHUM004620-PA Pediculus humanus (human body louse) PP13456 Pristionchus pacificus (nematode) 132378 Physcomitrella patens (moss) 161729 Physcomitrella patens (moss) 188359 Physcomitrella patens (moss) 190230 Physcomitrella patens (moss) ENSPPYP00000001666 Pongo pygmaeus (orangutan) 52084 Phytophthora ramorum (sudden oak death pathogen) 134225 Phytophthora sojae (root rot pathogen) 561839 Populus trichocarpa (black cottonwood) ENSPTRP00000001128 Pan troglodytes (chimpanzee) PVX_114705 Plasmodium vivax (protozoal parasite) ENSRNOP00000026704 Rattus norvegicus (norway rat) 4752451 Sorghum bicolor (sorghum) YHR026W Saccharomyces cerevisiae (budding yeast) Smp_064350 Schistosoma mansoni (trematode parasite) SPAC2C4.13 Schizosaccharomyces pombe (fission yeast) XP_001175579.1 Strongylocentrotus purpuratus (purple sea urchin) 64078 Trichoplax adhaerens (metazoa) TA11325 Theileria annulata (apicomplexan parasite) XP_975026.1 Tribolium castaneum (red flour beetle) Tc00.1047053506945.300 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000017203 Tetraodon nigroviridis (green spotted pufferfish) TP04_0832 Theileria parva (parasitic protozoan) 39278 Thalassiosira pseudonana (marine diatom) 3701.m00046 Tetrahymena thermophila (ciliate protozoa) 93204.m00203 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000007077 Xenopus tropicalis (frog) YALI0F09405g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV12316 LH15878 ISCW018464 FBgn0243444 FBgn0213019 FBgn0211769 FBgn0191863 FBgn0180670 JGI_V11_308098 FBgn0080021 FBgn0159291 FBgn0145721 FBgn0126982 FBgn0113152 FBgn0094187 CPIJ004794 BGIBMGA000231 ACYPI006833 GB17836 AGAP009334 AAEL012113 PB19871 PHUM004600 GLEAN_04599 GLEAN_00524
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	17135 w1118; P{EP}VhaPPA1-1EP3504/TM6B, Tb1
Harvard	- PBac{RB}VhaPPA1-1e03223
VDRC	v33342 w1118 P{GD2991}v33342 v33343 w1118; P{GD2991}v33343 v47187 w1118; P{GD16478}v47187 v47188 w1118; P{GD16478}v47188
Genomic Clones ( 2 )
	BACR08H11 BACR48E23 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 194 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH03514
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT23264 GH03023 GH12871 GH24369 GH24625 GH27165 GH27747 GM05062 GM15686 LD17944 LD31919 LD45146 LP03388 LP09105 LP18263 LP20984 LP21901 LP22247 RE03191 RE06981 RE09030 RE10182 RE10438 RE15920 RE16581 RE19902 RE20969 RE21841 RE21868 RE24527 RE25167 RE26780 RE28775 RE29573 RE34737 RE42202 RE42243 RE43004 RE45826 RE47505 RE56557 RE58539 RE70830 RE73092 RH03291 RH10906 RH17979 RH52378 RH53146 RH63276 RH66072 RH74233 SD04455 SD12324 SD13737 SD19846 SD20092 SD21411 SD22529 SD25151 SD26473 SD26616
Other clones	1417 39390 40041 70271 70374 190745 214381.36 524299 bs08b03 bs32f08 CK01.53A.E7 CK01.147B.C5 Dmel_neb_009862_0697_3561 Dmel_neb_010104_0655_3489 Dmel_neb_012842_0327_1035 Dmel_neb_013122_0393_3397 Dmel_neb_013668_0896_2999 EC056493 EK042820 EK094801 EK120711 EK152345 EK154235 EK197956 EK211409 EK293313 EN05129 EP12362 FGC027G10 FGM214A09 FGM214F04 FGM231A05 FGM238D06 RP003000809 RP003007027 RP003021598 RP003024539 RP003036563 RP003038861 RP003045725 RP003053216 RP003054788 RP003055211 RP003057530 RP003067263 RP003072788 RP003073641 RP003080709 RP003085496 RP003089431 RP003090404 RP003097469 RP003105963 RP003113233 RP003137287 RP003139652 RP003140384 RP003143248 RP003154740 RP003164436 RP003170310 RP003170548 RP003173223 RP003178654 RP003179015 RP003186247 RP003209320 RP003223308 RP003226553 RP003231419 RP003233278 RP003235730 RP003236183 RP003242506 RP003243237 RP003246698 RP003252952 RP003255656 RP003258566 RP003259735 RP003260507 RP003268338 RP003271592 RP003272639 RP003273618 RP003280680 RP003287376 RP003287621 RP003288664 RP003296665 RP003297651 RP003298718 RP003303670 RP003324903 RP003332911 RP003347688 RP003378320 RP003390647 RP003411510 RP003417680 RP003427718 RP003428086 RP003435249 RP003472331 RP003472332 RP003473978 RP003475287 RP003478341 RP003484837 RP003510139 RP003511642 RP003519605 RP003527608 RP003527835 RP003533165 RP003536204 RP003558476 RP003565132 RP003567259 RP003568146 RP003580911 RP003602633 RP003605543 RP003606107 RP003607321 RP003610026 RP003630596 RP003664667 RP003666261 RP003671522 RP003677803
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0028662 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 45247
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	RNAi screen using dsRNA made from templates generated with primers directed against this gene causes spindle pole detachment when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA. (Goshima et al., 2007) Area matching Drosophila EST AA539661. This EST has sequence similarity to Human proton ATPase like gene. (Davies, 2001.3.15)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_143753 RefSeq (Proteins) • NP_652010 DDBJ / EMBL / GenBank • AA539661 AAF55117 AAL25274 AI063607 AI401916 AI512965 AI945023 AX094232 AY060235 BE662234 CZ480996 Entrez Gene - A searchable database of RefSeq genes. • 45247 UniProtKB/TrEMBL • Q9VFE3
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • ATPase, V0 complex, proteolipid subunit C (IPR000245) ATPase, F0/V0 complex, subunit C (IPR002379)
Linkouts
	BioGRID - A database of protein and genetic interactions • 69537 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0028662 DroID - A comprehensive database of gene and protein interactions. • FBgn0028662 DRSC - Results from RNAi screens. • FBgn0028662 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0028662 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG7007-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0028662 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 45247 InParanoid A subset of ortholog calls from InParanoid. • AAEL012113-PA Aedes aegypti (mosquito) AGAP009334-PA Anopheles gambiae (mosquito) XP_392599.1 Apis mellifera (honey bee) XP_001951663.1 Acyrthosiphon pisum (pea aphid) At4g32530.1 Arabidopsis thaliana (wall cress) 7923 Batrachochytrium dendrobatidis (chytrid fungus) 114064 Branchiostoma floridae (lancelet) 88862 Branchiostoma floridae (lancelet) BGIBMGA000231-PA Bombyx mori (silk worm) ENSBTAP00000025144 Bos taurus (bovine) CAL0006331 Candida albicans (a form of yeast) CBP00885 Caenorhabditis briggsae (nematode) CE03595 Caenorhabditis elegans (worm) ENSCAFP00000007255 Canis familiaris (dog) CAGL0J00627g Candida glabrata (haploid yeast) Chro.80551 Cryptosporidium hominis (obligate parasite) ENSCINP00000017036 Ciona intestinalis (sea squirt) CMS332C Cyanidioschyzon merolae (red alga) cn10110 Cryptococcus neoformans (yeast-like fungus) cgd8_4790 Cryptosporidium parvum (protozoan parasite) CPIJ004794 Culex pipens (mosquito) ENSCPOP00000006767 Cavia porcellus (guinea pig) 120047 Chlamidomonas reinhardtii (green alga) RP29641 Caenorhabditis remanei (nematode) ENSCSAVP00000007323 Ciona savignyi (sedentary tunicate) 155226 Capitella spl (polychaete worm) DDB0167520 Dictyostelium discoideum (amoeba) DEHA2E16368g Debaryomyces Hansenii (yeast) 308098 Daphnia pulex (daphnia) ENSDARP00000045010 Danio rerio (zebra fish) ENSECAP00000021815 Equus caballus (horse) XP_649565 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000022738 Gymnopilus aculeatus (mushroom) ENSGALP00000016395 Gallus gallus (chicken) GL50803_15598 Giardia lamblia (flagellated protozoan) 186197 Hypsipyla robusta (cedar shoot borer) ENSP00000236067 Homo sapiens (human) ISCW018464-PA Ixodes scapularis (deer tick) KLLA0E11529g Kluyveromyces lactis (yeast) 223715 Lottia gigantea (owl limpet) LmjF30.3660 Leishmania major (virus) 17271 Monocosta brevicollis (choanoflagellate) ENSMODP00000003610 Monodelphis domestica (gray opossum) ENSMMUP00000040339 Macaca mulatta (rhesus monkey) ENSMUSP00000047682 Mus musculus (house mouse) 200737 Nematostella vectensis (starlet anemone) XP_001608002.1 Nasonia vitripennis (wasp) ENSOANP00000014335 Ornithorynchus anatinus (platypus) ENSORLP00000022196 Oryzias latipes (japanese killifish) LOC_Os01g42430.1 Oryza sativa (asian rice) 15314 Ostreococcus tauri (green alga) MAL13P1.271 Plasmodium falciparum (protozoal parasite) PHUM004620-PA Pediculus humanus (human body louse) PP13456 Pristionchus pacificus (nematode) 132378 Physcomitrella patens (moss) 161729 Physcomitrella patens (moss) 188359 Physcomitrella patens (moss) 190230 Physcomitrella patens (moss) ENSPPYP00000001666 Pongo pygmaeus (orangutan) 52084 Phytophthora ramorum (sudden oak death pathogen) 134225 Phytophthora sojae (root rot pathogen) 561839 Populus trichocarpa (black cottonwood) ENSPTRP00000001128 Pan troglodytes (chimpanzee) PVX_114705 Plasmodium vivax (protozoal parasite) ENSRNOP00000026704 Rattus norvegicus (norway rat) 4752451 Sorghum bicolor (sorghum) YHR026W Saccharomyces cerevisiae (budding yeast) Smp_064350 Schistosoma mansoni (trematode parasite) SPAC2C4.13 Schizosaccharomyces pombe (fission yeast) XP_001175579.1 Strongylocentrotus purpuratus (purple sea urchin) 64078 Trichoplax adhaerens (metazoa) TA11325 Theileria annulata (apicomplexan parasite) XP_975026.1 Tribolium castaneum (red flour beetle) Tc00.1047053506945.300 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000017203 Tetraodon nigroviridis (green spotted pufferfish) TP04_0832 Theileria parva (parasitic protozoan) 39278 Thalassiosira pseudonana (marine diatom) 3701.m00046 Tetrahymena thermophila (ciliate protozoa) 93204.m00203 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000007077 Xenopus tropicalis (frog) YALI0F09405g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 45247 modMine - Data generated by the modENCODE project. • FBgn0028662 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV12316 LH15878 ISCW018464 FBgn0243444 FBgn0213019 FBgn0211769 FBgn0191863 FBgn0180670 JGI_V11_308098 FBgn0080021 FBgn0159291 FBgn0145721 FBgn0126982 FBgn0113152 FBgn0094187 CPIJ004794 BGIBMGA000231 ACYPI006833 GB17836 AGAP009334 AAEL012113 PB19871 PHUM004600 GLEAN_04599 GLEAN_00524
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	CG7007 (Apidianakis et al., 2005, Goshima et al., 2007, Wang et al., 2004, Allan et al., 2005) V-ATPase (Dow and Davies, 2000) vhaPPA1-1 (Dow, 1999, Stark et al., 2005, Wang et al., 2004, Allan et al., 2005) VhaPPA1-1 (Buszczak et al., 2007, Goshima et al., 2007, Sessions et al., 2009, Ostrin et al., 2006, Seong et al., 2011)
Name Synonym	Vacuolar H+ ATPase subunit PPA1-1   V-ATPase proton pump (Sessions et al., 2009) VhaPPA1-1 (Ostrin et al., 2006)
Secondary FlyBase IDs
	FBgn0038278
References ( 29 )
Generate a list of	All references relating to this gene ( 29 )
List References by type	Research paper  ( 11 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 4 ) Abstract  ( 1 ) FlyBase analysis  ( 2 ) Patent  ( 1 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 3 ) Automatic genome annotation  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 2 )
	Seong et al., 2011, Biogerontology 12(2): 93--107 Genome-wide analysis of low-dose irradiated male Drosophila melanogaster with extended longevity. [FBrf0213307] Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Show all research papers ...