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Gene Dmel\Tbp-1

General Information
Symbol	Dmel\Tbp-1	Species	D. melanogaster
Name	Tat-binding protein-1	Annotation symbol	CG10370
Feature type	protein_coding_gene	FlyBase ID	FBgn0028684
Gene Model Status	Current	Stock availability	4 publicly available
Also Known As	p50, Rpt5, l(3)04210
Genomic Location
Chromosome (arm)	3R	Recombination map
Cytogenetic map	95B1-95B1	Sequence location	3R:19,578,600..19,580,345 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Tat-binding protein-1 is referred to in FlyBase by the symbol Dmel\Tbp-1 (CG10370, FBgn0028684). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: endopeptidase activity. There is experimental evidence that it is involved in the biological process: cellular process; proteolysis. 7 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: 26S proteasome subunit P45; ATPase, AAA+ type, core; ATPase, AAA-type, conserved site; ATPase, AAA-type, core. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult male reproductive system. Comments on Affy2 ProbeSet: ProbeSet 1629676_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Tbp-1. Gene sequence location is 3R:19578600..19580345.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features BKN21879 HFA16842
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 95B1-95B1   Limits computationally determined from genome sequence between P{PZ}l(3)0690606906 and P{PZ}l(3)0468404684
Experimentally Determined Cytological Location
Cytogenetic map Notes References 95B1-95B2   (determined by in situ hybridisation)   (Misra, 2000.8.11) 95B-95B     (Fermin, 1999.3.11)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Tbp-1 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Tbp-1-RA FBtr0084452  NM_079740   1625   428
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Tbp-1-PA   FBpp0083843   47.8   428   4.97     NP_524464   AAF56177
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • ATPase, AAA+ type, core (IPR003593) ATPase, AAA-type, core (IPR003959) ATPase, AAA-type, conserved site (IPR003960) 26S proteasome subunit P45 (IPR005937)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA696709   AA699086   AA802623   AA940763   AE014297 AAF56177   AF134402 AAD24194   AF145305 AAF08386   AF160882 AAD46823   AI134568   AI258884   AI402278   AI456583   AI456896   AI519868   AI520408   AQ026194   AX201624   AX201625   AX201626   AY231693   BF485720   BF485836   BF500751   BF506208   BI142043   BI170581   BI170916   BI173187   BI215392   BI354320   BI354335   BI364803   BI371967   BI483714   BI485147   BI579925   BP547670   BP560273   BQ103707   CO193255   CO193844   CO194517   CO195657   CO269314   CO320925   CO338092   CZ467523   DN154006   EC078776   EC197205   EC233688   EC262514   EV587976   FE863335   FE863363   FE863394   FE863419   GH740291   GH741118   GH743301   GH744941   GH746528   GH762016   GH762950   GH765412   GH766470   GH767402   GH767719   GH768154   GH768932
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9V3V6 Q9XZC3
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0028684    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0028684 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0028684 expression level Developmental Stage   Expression Level embryo 00-02hr    13212 embryo 02-04hr    2698 embryo 04-06hr    6185 embryo 06-08hr    6269 embryo 08-10hr    4923 embryo 10-12hr    4310 embryo 12-14hr    3537 embryo 14-16hr    3006 embryo 16-18hr    2375 embryo 18-20hr    1707 embryo 20-22hr    1484 embryo 22-24hr    1784 larva L1    3309 larva L2    6457 larva L3 12hr old    4243 larva L3 puffstage 1-2    7380 larva L3 puffstage 3-6    12815 larva L3 puffstage 7-9    20898 white prepupae new    25190 white prepupae 12hr    8066 white prepupae 24hr    8489 pupae 2d postWPP    5885 pupae 3d postWPP    4757 pupae 4d postWPP    7742 adult male 01day    5739 adult male 05day    4800 adult male 30day    4845 adult female 01day    7914 adult female 05day    10934 adult female 30day    9923 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (13212) embryo 02-04hr  (2698) embryo 04-06hr  (6185) embryo 06-08hr  (6269) embryo 08-10hr  (4923) embryo 10-12hr  (4310) embryo 12-14hr  (3537) embryo 14-16hr  (3006) embryo 16-18hr  (2375) embryo 18-20hr  (1707) embryo 20-22hr  (1484) embryo 22-24hr  (1784) larva L1  (3309) larva L2  (6457) larva L3 12hr old  (4243) larva L3 puffstage 1-2  (7380) larva L3 puffstage 3-6  (12815) larva L3 puffstage 7-9  (20898) white prepupae new  (25190) white prepupae 12hr  (8066) white prepupae 24hr  (8489) pupae 2d postWPP  (5885) pupae 3d postWPP  (4757) pupae 4d postWPP  (7742) adult male 01day  (5739) adult male 05day  (4800) adult male 30day  (4845) adult female 01day  (7914) adult female 05day  (10934) adult female 30day  (9923) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (13212) embryo 02-04hr  (2698) embryo 04-06hr  (6185) embryo 06-08hr  (6269) embryo 08-10hr  (4923) embryo 10-12hr  (4310) embryo 12-14hr  (3537) embryo 14-16hr  (3006) embryo 16-18hr  (2375) embryo 18-20hr  (1707) embryo 20-22hr  1484 embryo 22-24hr  (1784) larva L1  (3309) larva L2  (6457) larva L3 12hr old  (4243) larva L3 puffstage 1-2  (7380) larva L3 puffstage 3-6  (12815) larva L3 puffstage 7-9  (20898) white prepupae new  (25190) white prepupae 12hr  (8066) white prepupae 24hr  (8489) pupae 2d postWPP  (5885) pupae 3d postWPP  (4757) pupae 4d postWPP  (7742) adult male 01day  (5739) adult male 05day  (4800) adult male 30day  (4845) adult female 01day  (7914) adult female 05day  (10934) adult female 30day  (9923) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (13212) embryo 02-04hr    2698 embryo 04-06hr    6185 embryo 06-08hr    6269 embryo 08-10hr    4923 embryo 10-12hr    4310 embryo 12-14hr    3537 embryo 14-16hr    3006 embryo 16-18hr    2375 embryo 18-20hr    1707 embryo 20-22hr    1484 embryo 22-24hr    1784 larva L1    3309 larva L2    6457 larva L3 12hr old    4243 larva L3 puffstage 1-2    7380 larva L3 puffstage 3-6  (12815) larva L3 puffstage 7-9  (20898) white prepupae new  (25190) white prepupae 12hr    8066 white prepupae 24hr    8489 pupae 2d postWPP    5885 pupae 3d postWPP    4757 pupae 4d postWPP    7742 adult male 01day    5739 adult male 05day    4800 adult male 30day    4845 adult female 01day    7914 adult female 05day  (10934) adult female 30day    9923 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    13212 embryo 02-04hr    2698 embryo 04-06hr    6185 embryo 06-08hr    6269 embryo 08-10hr    4923 embryo 10-12hr    4310 embryo 12-14hr    3537 embryo 14-16hr    3006 embryo 16-18hr    2375 embryo 18-20hr    1707 embryo 20-22hr    1484 embryo 22-24hr    1784 larva L1    3309 larva L2    6457 larva L3 12hr old    4243 larva L3 puffstage 1-2    7380 larva L3 puffstage 3-6    12815 larva L3 puffstage 7-9    20898 white prepupae new    25190 white prepupae 12hr    8066 white prepupae 24hr    8489 pupae 2d postWPP    5885 pupae 3d postWPP    4757 pupae 4d postWPP    7742 adult male 01day    5739 adult male 05day    4800 adult male 30day    4845 adult female 01day    7914 adult female 05day    10934 adult female 30day    9923 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0028684 expression level Developmental Stage   Expression Level embryo 00-02hr    13212 embryo 02-04hr    2698 embryo 04-06hr    6185 embryo 06-08hr    6269 embryo 08-10hr    4923 embryo 10-12hr    4310 embryo 12-14hr    3537 embryo 14-16hr    3006 embryo 16-18hr    2375 embryo 18-20hr    1707 embryo 20-22hr    1484 embryo 22-24hr    1784 larva L1    3309 larva L2    6457 larva L3 12hr old    4243 larva L3 puffstage 1-2    7380 larva L3 puffstage 3-6    12815 larva L3 puffstage 7-9    20898 white prepupae new    25190 white prepupae 12hr    8066 white prepupae 24hr    8489 pupae 2d postWPP    5885 pupae 3d postWPP    4757 pupae 4d postWPP    7742 adult male 01day    5739 adult male 05day    4800 adult male 30day    4845 adult female 01day    7914 adult female 05day    10934 adult female 30day    9923 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (13212) embryo 02-04hr  (2698) embryo 04-06hr  (6185) embryo 06-08hr  (6269) embryo 08-10hr  (4923) embryo 10-12hr  (4310) embryo 12-14hr  (3537) embryo 14-16hr  (3006) embryo 16-18hr  (2375) embryo 18-20hr  (1707) embryo 20-22hr  (1484) embryo 22-24hr  (1784) larva L1  (3309) larva L2  (6457) larva L3 12hr old  (4243) larva L3 puffstage 1-2  (7380) larva L3 puffstage 3-6  (12815) larva L3 puffstage 7-9  (20898) white prepupae new  (25190) white prepupae 12hr  (8066) white prepupae 24hr  (8489) pupae 2d postWPP  (5885) pupae 3d postWPP  (4757) pupae 4d postWPP  (7742) adult male 01day  (5739) adult male 05day  (4800) adult male 30day  (4845) adult female 01day  (7914) adult female 05day  (10934) adult female 30day  (9923) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (13212) embryo 02-04hr  (2698) embryo 04-06hr  (6185) embryo 06-08hr  (6269) embryo 08-10hr  (4923) embryo 10-12hr  (4310) embryo 12-14hr  (3537) embryo 14-16hr  (3006) embryo 16-18hr  2375 embryo 18-20hr  1707 embryo 20-22hr  1484 embryo 22-24hr  1784 larva L1  (3309) larva L2  (6457) larva L3 12hr old  (4243) larva L3 puffstage 1-2  (7380) larva L3 puffstage 3-6  (12815) larva L3 puffstage 7-9  (20898) white prepupae new  (25190) white prepupae 12hr  (8066) white prepupae 24hr  (8489) pupae 2d postWPP  (5885) pupae 3d postWPP  (4757) pupae 4d postWPP  (7742) adult male 01day  (5739) adult male 05day  (4800) adult male 30day  (4845) adult female 01day  (7914) adult female 05day  (10934) adult female 30day  (9923) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  13212 embryo 02-04hr    2698 embryo 04-06hr    6185 embryo 06-08hr    6269 embryo 08-10hr    4923 embryo 10-12hr    4310 embryo 12-14hr    3537 embryo 14-16hr    3006 embryo 16-18hr    2375 embryo 18-20hr    1707 embryo 20-22hr    1484 embryo 22-24hr    1784 larva L1    3309 larva L2    6457 larva L3 12hr old    4243 larva L3 puffstage 1-2    7380 larva L3 puffstage 3-6  12815 larva L3 puffstage 7-9  (20898) white prepupae new  (25190) white prepupae 12hr    8066 white prepupae 24hr    8489 pupae 2d postWPP    5885 pupae 3d postWPP    4757 pupae 4d postWPP    7742 adult male 01day    5739 adult male 05day    4800 adult male 30day    4845 adult female 01day    7914 adult female 05day  10934 adult female 30day    9923 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    13212 embryo 02-04hr    2698 embryo 04-06hr    6185 embryo 06-08hr    6269 embryo 08-10hr    4923 embryo 10-12hr    4310 embryo 12-14hr    3537 embryo 14-16hr    3006 embryo 16-18hr    2375 embryo 18-20hr    1707 embryo 20-22hr    1484 embryo 22-24hr    1784 larva L1    3309 larva L2    6457 larva L3 12hr old    4243 larva L3 puffstage 1-2    7380 larva L3 puffstage 3-6    12815 larva L3 puffstage 7-9    20898 white prepupae new    25190 white prepupae 12hr    8066 white prepupae 24hr    8489 pupae 2d postWPP    5885 pupae 3d postWPP    4757 pupae 4d postWPP    7742 adult male 01day    5739 adult male 05day    4800 adult male 30day    4845 adult female 01day    7914 adult female 05day    10934 adult female 30day    9923 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0028684    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0028684 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult male reproductive system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0028684 expression level Tissue   Expression Level Larval Central Nervous System    630.5 Larval Midgut    754.1 Larval Hindgut    831.7 Larval Malpighian Tubules    1929.2 Larval Fat Body    920.8 Larval Salivary Gland    1037 Larval Trachea    780.4 Larval Carcass    1462.475 Adult Head    323.2 Adult Eye    267.75 Adult Brain    230 Adult Thoracic-Abdominal Ganglion    240.7 Adult Crop    660.1 Adult Midgut    579.1 Adult Hindgut    508.6 Adult Malpighian Tubules    715.1 Adult Fat Body    801.4 Adult Salivary Gland    579.3 Adult Heart    937 Adult VirginFemale Spermatheca    630.6 Adult InseminatedFemale Spermatheca    639.2 Adult Ovary    856.3 Adult Testis    393.6 Adult Male Accessory Gland    457.2 Adult Carcass    602.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (630.5) Larval Midgut  (754.1) Larval Hindgut  (831.7) Larval Malpighian Tubules  (1929.2) Larval Fat Body  (920.8) Larval Salivary Gland  (1037) Larval Trachea  (780.4) Larval Carcass  (1462.475) Adult Head    323.2 Adult Eye    267.75 Adult Brain    230 Adult Thoracic-Abdominal Ganglion    240.7 Adult Crop  (660.1) Adult Midgut  (579.1) Adult Hindgut  508.6 Adult Malpighian Tubules  (715.1) Adult Fat Body  (801.4) Adult Salivary Gland  (579.3) Adult Heart  (937) Adult VirginFemale Spermatheca  (630.6) Adult InseminatedFemale Spermatheca  (639.2) Adult Ovary  (856.3) Adult Testis    393.6 Adult Male Accessory Gland    457.2 Adult Carcass  (602.7) Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    630.5 Larval Midgut    754.1 Larval Hindgut    831.7 Larval Malpighian Tubules  (1929.2) Larval Fat Body    920.8 Larval Salivary Gland  1037 Larval Trachea    780.4 Larval Carcass  (1462.475) Adult Head    323.2 Adult Eye    267.75 Adult Brain    230 Adult Thoracic-Abdominal Ganglion    240.7 Adult Crop    660.1 Adult Midgut    579.1 Adult Hindgut    508.6 Adult Malpighian Tubules    715.1 Adult Fat Body    801.4 Adult Salivary Gland    579.3 Adult Heart    937 Adult VirginFemale Spermatheca    630.6 Adult InseminatedFemale Spermatheca    639.2 Adult Ovary    856.3 Adult Testis    393.6 Adult Male Accessory Gland    457.2 Adult Carcass    602.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    630.5 Larval Midgut    754.1 Larval Hindgut    831.7 Larval Malpighian Tubules    1929.2 Larval Fat Body    920.8 Larval Salivary Gland    1037 Larval Trachea    780.4 Larval Carcass    1462.475 Adult Head    323.2 Adult Eye    267.75 Adult Brain    230 Adult Thoracic-Abdominal Ganglion    240.7 Adult Crop    660.1 Adult Midgut    579.1 Adult Hindgut    508.6 Adult Malpighian Tubules    715.1 Adult Fat Body    801.4 Adult Salivary Gland    579.3 Adult Heart    937 Adult VirginFemale Spermatheca    630.6 Adult InseminatedFemale Spermatheca    639.2 Adult Ovary    856.3 Adult Testis    393.6 Adult Male Accessory Gland    457.2 Adult Carcass    602.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0028684 expression level Tissue   Expression Level Larval Central Nervous System    630.5 Larval Midgut    754.1 Larval Hindgut    831.7 Larval Malpighian Tubules    1929.2 Larval Fat Body    920.8 Larval Salivary Gland    1037 Larval Trachea    780.4 Larval Carcass    1462.475 Adult Head    323.2 Adult Eye    267.75 Adult Brain    230 Adult Thoracic-Abdominal Ganglion    240.7 Adult Crop    660.1 Adult Midgut    579.1 Adult Hindgut    508.6 Adult Malpighian Tubules    715.1 Adult Fat Body    801.4 Adult Salivary Gland    579.3 Adult Heart    937 Adult VirginFemale Spermatheca    630.6 Adult InseminatedFemale Spermatheca    639.2 Adult Ovary    856.3 Adult Testis    393.6 Adult Male Accessory Gland    457.2 Adult Carcass    602.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  630.5 Larval Midgut  754.1 Larval Hindgut  (831.7) Larval Malpighian Tubules  (1929.2) Larval Fat Body  (920.8) Larval Salivary Gland  (1037) Larval Trachea  780.4 Larval Carcass  (1462.475) Adult Head    323.2 Adult Eye    267.75 Adult Brain    230 Adult Thoracic-Abdominal Ganglion    240.7 Adult Crop  660.1 Adult Midgut  579.1 Adult Hindgut  508.6 Adult Malpighian Tubules  715.1 Adult Fat Body  801.4 Adult Salivary Gland  579.3 Adult Heart  (937) Adult VirginFemale Spermatheca  630.6 Adult InseminatedFemale Spermatheca  639.2 Adult Ovary  (856.3) Adult Testis    393.6 Adult Male Accessory Gland    457.2 Adult Carcass  602.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    630.5 Larval Midgut    754.1 Larval Hindgut    831.7 Larval Malpighian Tubules  (1929.2) Larval Fat Body    920.8 Larval Salivary Gland  1037 Larval Trachea    780.4 Larval Carcass  1462.475 Adult Head    323.2 Adult Eye    267.75 Adult Brain    230 Adult Thoracic-Abdominal Ganglion    240.7 Adult Crop    660.1 Adult Midgut    579.1 Adult Hindgut    508.6 Adult Malpighian Tubules    715.1 Adult Fat Body    801.4 Adult Salivary Gland    579.3 Adult Heart    937 Adult VirginFemale Spermatheca    630.6 Adult InseminatedFemale Spermatheca    639.2 Adult Ovary    856.3 Adult Testis    393.6 Adult Male Accessory Gland    457.2 Adult Carcass    602.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    630.5 Larval Midgut    754.1 Larval Hindgut    831.7 Larval Malpighian Tubules    1929.2 Larval Fat Body    920.8 Larval Salivary Gland    1037 Larval Trachea    780.4 Larval Carcass    1462.475 Adult Head    323.2 Adult Eye    267.75 Adult Brain    230 Adult Thoracic-Abdominal Ganglion    240.7 Adult Crop    660.1 Adult Midgut    579.1 Adult Hindgut    508.6 Adult Malpighian Tubules    715.1 Adult Fat Body    801.4 Adult Salivary Gland    579.3 Adult Heart    937 Adult VirginFemale Spermatheca    630.6 Adult InseminatedFemale Spermatheca    639.2 Adult Ovary    856.3 Adult Testis    393.6 Adult Male Accessory Gland    457.2 Adult Carcass    602.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    323.2   NA  Eye    267.75   NA  Brain    230   630.5  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    240.7   NA  Crop    660.1   754.1  Midgut    579.1   831.7  Hindgut    508.6   1929.2  Malpighian Tubules    715.1   920.8  Fat Body    801.4   1037  Salivary Gland    579.3   NA  Heart    937   780.4  Trachea    NA   NA  VirginFemale Spermatheca    630.6   NA  InseminatedFemale Spermatheca    639.2   NA  Ovary    856.3   NA  Testis    393.6   NA  Male Accessory Gland    457.2   1462.475  Carcass    602.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_02
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0028684 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10370-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Tbp-1 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal | pupal stage, with Scer\GAL4pnr-MD237 Tbp-1GD6960 lethal | recessive Tbp-104210b Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of Tbp-1 Class Mutagen Stocks Known lesion Tbp-104210b P-element activity 1 -- Tbp-1DG19608 P-element activity 1 -- Tbp-1c01875 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Tbp-1 Class Mutagen Stocks Known lesion Tbp-1HMS00417 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Tbp-1KK101828 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes Tbp-1dsRNA.cWa in vitro construct - RNAi 0 Yes Tbp-1GD6960 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3R)BSC489 (Christensen et al., 2008.4.15) Df(3R)BSC490 (Christensen et al., 2008.4.15) Df(3R)Exel9013 (Ryder, 2004.4.26)
Not disrupted in	Df(3R)c(3)G-2 (BDGP Project Members, 1994-1999) Df(3R)sbd105 (Spradling et al., 1999)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD6960} NA P{KK101828} NA P{TRiP.HMS00417} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{PZ}Tbp-104210b No miscellaneous insertions P{PTT-GB}RanBP3CB02343 NA P{wHy}Tbp-1DG19608 NA PBac{PB}Tbp-1c01875 NA
Gene Ontology: Function, Process & Cellular Component ( 9 unique terms )
Terms Based on Experimental Evidence ( 4 terms )
Molecular Function
CV term Evidence References
endopeptidase activity inferred from direct assay (Holzl et al., 2000)
Biological Process
CV term Evidence References
cellular process inferred from mutant phenotype (Boutros et al., 2004) proteolysis inferred from direct assay AND inferred from sequence or structural similarity with human PSMC3 AND inferred from sequence or structural similarity with Saccharomyces RPT5 (Holzl et al., 2000)
Cellular Component
CV term Evidence References
proteasome regulatory particle inferred from direct assay AND inferred from sequence or structural similarity with human PSMC3 (Holzl et al., 2000)
Terms Based on Predictions or Assertions ( 6 terms )
Molecular Function
CV term Evidence References
ATPase activity inferred from sequence or structural similarity with Saccharomyces RPT5 (Holzl et al., 2000) ATP binding inferred from electronic annotation with InterPro:IPR003959, InterPro:IPR003960 (FlyBase Curators et al., 2004-) endopeptidase activity non-traceable author statement (Fermin, 1999.3.11)
Biological Process
CV term Evidence References
protein catabolic process inferred from electronic annotation with InterPro:IPR005937 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
cytoplasm inferred from electronic annotation with InterPro:IPR005937 (FlyBase Curators et al., 2004-) proteasome regulatory particle, base subcomplex inferred from sequence or structural similarity with Saccharomyces RPT5 (Holzl et al., 2000) non-traceable author statement (Fermin, 1999.3.11, Hoelzl, 1999.4.23)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Tbp-1 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0028684 DroID - A comprehensive database of gene and protein interactions. • FBgn0028684 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42805
Orthologs
Genome-wide drosophilid orthologs	Dana\GF16259 Dere\GG11226 Dgri\GH23603 Dmoj\GI10364 Dper\GL23259 Dpse\GA10280 Dsec\GM26527 Dsim\GD21035 Dvir\GJ22583 Dwil\GK22416 Dyak\Tbp-1
Curated drosophilid orthologs	Dpse\GA10280   Dyak\Tbp-1
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL002508-PA Aedes aegypti (mosquito) AGAP000616-PA Anopheles gambiae (mosquito) XP_392722.1 Apis mellifera (honey bee) XP_001948697.1 Acyrthosiphon pisum (pea aphid) At3g05530.1 Arabidopsis thaliana (wall cress) 37257 Batrachochytrium dendrobatidis (chytrid fungus) 124826 Branchiostoma floridae (lancelet) XP_001893780.1 Brugia malayi (roundworm nematode) BGIBMGA004782-PA Bombyx mori (silk worm) ENSBTAP00000028983 Bos taurus (bovine) CAL0002261 Candida albicans (a form of yeast) CBP03138 Caenorhabditis briggsae (nematode) CE17915 Caenorhabditis elegans (worm) ENSCAFP00000012805 Canis familiaris (dog) CAGL0A02750g Candida glabrata (haploid yeast) Chro.20147 Cryptosporidium hominis (obligate parasite) ENSCINP00000007032 Ciona intestinalis (sea squirt) JA03812 Caenorhabditis japonica (nematode) CMP294C Cyanidioschyzon merolae (red alga) cn13144 Cryptococcus neoformans (yeast-like fungus) cgd2_1350 Cryptosporidium parvum (protozoan parasite) CPIJ016407 Culex pipens (mosquito) ENSCPOP00000007350 Cavia porcellus (guinea pig) 99595 Chlamidomonas reinhardtii (green alga) RP22456 Caenorhabditis remanei (nematode) ENSCSAVP00000005095 Ciona savignyi (sedentary tunicate) 225374 Capitella spl (polychaete worm) DDB0232967 Dictyostelium discoideum (amoeba) DEHA2G13024g Debaryomyces Hansenii (yeast) 299812 Daphnia pulex (daphnia) ENSDARP00000026554 Danio rerio (zebra fish) ENSECAP00000022376 Equus caballus (horse) XP_657099 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000021305 Gymnopilus aculeatus (mushroom) ENSGALP00000037708 Gallus gallus (chicken) GL50803_4365 Giardia lamblia (flagellated protozoan) 184825 Hypsipyla robusta (cedar shoot borer) ENSP00000298852 Homo sapiens (human) KLLA0E21209g Kluyveromyces lactis (yeast) 207066 Lottia gigantea (owl limpet) LmjF22.0620 Leishmania major (virus) 35277 Monocosta brevicollis (choanoflagellate) ENSMODP00000024839 Monodelphis domestica (gray opossum) ENSMMUP00000020482 Macaca mulatta (rhesus monkey) ENSMUSP00000002171 Mus musculus (house mouse) 244951 Nematostella vectensis (starlet anemone) XP_001604886.1 Nasonia vitripennis (wasp) ENSOANP00000004499 Ornithorynchus anatinus (platypus) ENSORLP00000013507 Oryzias latipes (japanese killifish) LOC_Os02g56000.1 Oryza sativa (asian rice) 8530 Ostreococcus tauri (green alga) PF11_0314 Plasmodium falciparum (protozoal parasite) PHUM000792-PA Pediculus humanus (human body louse) PP12460 Pristionchus pacificus (nematode) 144700 Physcomitrella patens (moss) ENSPPYP00000003790 Pongo pygmaeus (orangutan) 71146 Phytophthora ramorum (sudden oak death pathogen) 108207 Phytophthora sojae (root rot pathogen) 581882 Populus trichocarpa (black cottonwood) ENSPTRP00000006195 Pan troglodytes (chimpanzee) PVX_092125 Plasmodium vivax (protozoal parasite) ENSRNOP00000015910 Rattus norvegicus (norway rat) 133968 Sorghum bicolor (sorghum) YOR117W Saccharomyces cerevisiae (budding yeast) Smp_042270.2 Schistosoma mansoni (trematode parasite) SPAC3A11.12c Schizosaccharomyces pombe (fission yeast) XP_782191.2 Strongylocentrotus purpuratus (purple sea urchin) 49668 Trichoplax adhaerens (metazoa) TA21405 Theileria annulata (apicomplexan parasite) XP_967673.1 Tribolium castaneum (red flour beetle) Tc00.1047053506859.20 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000020832 Tetraodon nigroviridis (green spotted pufferfish) TP01_0290 Theileria parva (parasitic protozoan) 516 Thalassiosira pseudonana (marine diatom) ENSTRUP00000018255 Takifugu rubripes (pufferfish Takifugu) 3698.m00129 Tetrahymena thermophila (ciliate protozoa) 81529.m00529 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000017362 Xenopus tropicalis (frog) YALI0D09119g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV15940 ISCW004146 FBgn0068021 FBgn0224395 FBgn0209690 FBgn0192490 FBgn0181380 JGI_V11_299812 FBgn0070338 FBgn0160849 FBgn0133128 FBgn0131060 FBgn0103527 FBgn0093281 CPIJ016407 BGIBMGA004782 ACYPI004185 GB14678 AGAP000616 AAEL002508 PB23138 PHUM043100 GLEAN_10100
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	32422 y1 sc* v1; P{TRiP.HMS00417}attP2/TM3, Sb1 21697 y1 w67c23; P{wHy}RanBP3DG19608 P{wHy}Tbp-1DG19608 11625 ry506 P{PZ}04210a P{PZ}Tbp-104210b/TM3, ryRK Sb1 Ser1
VDRC	v105133 P{KK101828}VIE-260B
Genomic Clones ( 2 )
	BACR11E07 BACR16I18 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 61 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH12068
Other clones	DPiM_GH12068 yak-em_Tbp
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT08624 AT15772 AT19673 AT19890 GM06024 GM08220 GM20719 GM21364 HL07443 LD22987 LD36650 LD37061 LD39695 LD40560 LP02182 RE12090 RE12541 RE15949 RE21780 RE49987 RE55625 RE66638 RE68431 RE74033 SD16038
Other clones	38243 184130 569941 CK01.122C.D3 Dmel_neb_006805_0124_3394 EC28871 EC35387 EC36887 EC38686 EC40737 EK094114 EK288809 EN15932 FGH119D11 FGM325F04 RM06636 RM06736 RM07036 RM07236 RP001003671 RP001006537 RP001010956 RP001013894 RP001018167 RP001019936 RP001019951 RP001024603 RP001034656 RP001038440 RP001040149 RP001041308 RP001051349 UUGC1118
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0028684 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42805
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: Pros26S-RS6A CG10370 (Misra, 2000.8.11) Source for merge of: Rpt5 BcDNA:GH12068 (FlyBase, 1996-) Source for merge of: Rpt5 Tbp-1 (FlyBase, 1996-) Source for merge of: Tbp-1 anon-WO0153538.10 anon-WO0153538.8 anon-WO0153538.9 (FlyBase, 1996-) Source for merge of: Tbp-1 Pros26S-RS6A (FlyBase, 1996-)
Additional comments	Source for merge of Tbp-1 Pros26S-RS6A was sequence comparison (date:000811). (FlyBase, 1996-) Source for merge of Tbp-1 anon-WO0153538.10 anon-WO0153538.8 anon-WO0153538.9 was sequence comparison (date:051113). (FlyBase, 1996-) Source for merge of Rpt5 BcDNA:GH12068 was sequence comparison (date:991228). (FlyBase, 1996-) Source for merge of Rpt5 Tbp-1 was sequence comparison (date:000120). (FlyBase, 1996-)
Other Comments
	RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells. (Boutros et al., 2004) RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells. (Boutros et al., 2004)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_079740 RefSeq (Proteins) • NP_524464 DDBJ / EMBL / GenBank • AA802623 AA940763 AAD24194 AAD46823 AAF08386 AAF56177 AF134402 AF145305 AF160882 AI134568 AI402278 AQ026194 AX201624 AX201625 AX201626 CZ467523 Entrez Gene - A searchable database of RefSeq genes. • 42805 UniProtKB/TrEMBL • Q9V3V6 Q9XZC3
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • ATPase, AAA+ type, core (IPR003593) ATPase, AAA-type, core (IPR003959) ATPase, AAA-type, conserved site (IPR003960) 26S proteasome subunit P45 (IPR005937)
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0028684 DroID - A comprehensive database of gene and protein interactions. • FBgn0028684 DRSC - Results from RNAi screens. • FBgn0028684 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0028684 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10370-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0028684 FlyReactome - A curated knowledgebase of Drosophila melanogaster pathways • 205589 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 42805 InParanoid A subset of ortholog calls from InParanoid. • AAEL002508-PA Aedes aegypti (mosquito) AGAP000616-PA Anopheles gambiae (mosquito) XP_392722.1 Apis mellifera (honey bee) XP_001948697.1 Acyrthosiphon pisum (pea aphid) At3g05530.1 Arabidopsis thaliana (wall cress) 37257 Batrachochytrium dendrobatidis (chytrid fungus) 124826 Branchiostoma floridae (lancelet) XP_001893780.1 Brugia malayi (roundworm nematode) BGIBMGA004782-PA Bombyx mori (silk worm) ENSBTAP00000028983 Bos taurus (bovine) CAL0002261 Candida albicans (a form of yeast) CBP03138 Caenorhabditis briggsae (nematode) CE17915 Caenorhabditis elegans (worm) ENSCAFP00000012805 Canis familiaris (dog) CAGL0A02750g Candida glabrata (haploid yeast) Chro.20147 Cryptosporidium hominis (obligate parasite) ENSCINP00000007032 Ciona intestinalis (sea squirt) JA03812 Caenorhabditis japonica (nematode) CMP294C Cyanidioschyzon merolae (red alga) cn13144 Cryptococcus neoformans (yeast-like fungus) cgd2_1350 Cryptosporidium parvum (protozoan parasite) CPIJ016407 Culex pipens (mosquito) ENSCPOP00000007350 Cavia porcellus (guinea pig) 99595 Chlamidomonas reinhardtii (green alga) RP22456 Caenorhabditis remanei (nematode) ENSCSAVP00000005095 Ciona savignyi (sedentary tunicate) 225374 Capitella spl (polychaete worm) DDB0232967 Dictyostelium discoideum (amoeba) DEHA2G13024g Debaryomyces Hansenii (yeast) 299812 Daphnia pulex (daphnia) ENSDARP00000026554 Danio rerio (zebra fish) ENSECAP00000022376 Equus caballus (horse) XP_657099 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000021305 Gymnopilus aculeatus (mushroom) ENSGALP00000037708 Gallus gallus (chicken) GL50803_4365 Giardia lamblia (flagellated protozoan) 184825 Hypsipyla robusta (cedar shoot borer) ENSP00000298852 Homo sapiens (human) KLLA0E21209g Kluyveromyces lactis (yeast) 207066 Lottia gigantea (owl limpet) LmjF22.0620 Leishmania major (virus) 35277 Monocosta brevicollis (choanoflagellate) ENSMODP00000024839 Monodelphis domestica (gray opossum) ENSMMUP00000020482 Macaca mulatta (rhesus monkey) ENSMUSP00000002171 Mus musculus (house mouse) 244951 Nematostella vectensis (starlet anemone) XP_001604886.1 Nasonia vitripennis (wasp) ENSOANP00000004499 Ornithorynchus anatinus (platypus) ENSORLP00000013507 Oryzias latipes (japanese killifish) LOC_Os02g56000.1 Oryza sativa (asian rice) 8530 Ostreococcus tauri (green alga) PF11_0314 Plasmodium falciparum (protozoal parasite) PHUM000792-PA Pediculus humanus (human body louse) PP12460 Pristionchus pacificus (nematode) 144700 Physcomitrella patens (moss) ENSPPYP00000003790 Pongo pygmaeus (orangutan) 71146 Phytophthora ramorum (sudden oak death pathogen) 108207 Phytophthora sojae (root rot pathogen) 581882 Populus trichocarpa (black cottonwood) ENSPTRP00000006195 Pan troglodytes (chimpanzee) PVX_092125 Plasmodium vivax (protozoal parasite) ENSRNOP00000015910 Rattus norvegicus (norway rat) 133968 Sorghum bicolor (sorghum) YOR117W Saccharomyces cerevisiae (budding yeast) Smp_042270.2 Schistosoma mansoni (trematode parasite) SPAC3A11.12c Schizosaccharomyces pombe (fission yeast) XP_782191.2 Strongylocentrotus purpuratus (purple sea urchin) 49668 Trichoplax adhaerens (metazoa) TA21405 Theileria annulata (apicomplexan parasite) XP_967673.1 Tribolium castaneum (red flour beetle) Tc00.1047053506859.20 Trypanosoma cruzi (parasitic trypanosome) ENSTNIP00000020832 Tetraodon nigroviridis (green spotted pufferfish) TP01_0290 Theileria parva (parasitic protozoan) 516 Thalassiosira pseudonana (marine diatom) ENSTRUP00000018255 Takifugu rubripes (pufferfish Takifugu) 3698.m00129 Tetrahymena thermophila (ciliate protozoa) 81529.m00529 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000017362 Xenopus tropicalis (frog) YALI0D09119g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 42805 modMine - Data generated by the modENCODE project. • FBgn0028684 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV15940 ISCW004146 FBgn0068021 FBgn0224395 FBgn0209690 FBgn0192490 FBgn0181380 JGI_V11_299812 FBgn0070338 FBgn0160849 FBgn0133128 FBgn0131060 FBgn0103527 FBgn0093281 CPIJ016407 BGIBMGA004782 ACYPI004185 GB14678 AGAP000616 AAEL002508 PB23138 PHUM043100 GLEAN_10100
Synonyms & Secondary IDs ( 21 )
Reported As
Symbol Synonym	anon-WO0153538.8   anon-WO0153538.9   anon-WO0153538.10   BcDNA:GH12068   BcDNA.GH12068 (Tsang, 1999.6.19) CG10370 (Barbash and Lorigan, 2007, Keleman et al., 2009.8.5, Ma et al., 2002, Ni et al., 2010.12.1) Dm_Rpt5a (Wollenberg and Swaffield, 2001) Dm_Rpt5b (Wollenberg and Swaffield, 2001) DmTBP-1 (Frohlich, 2001) dRpt5 (Wojcik and DeMartino, 2002) l(3)04210 (Beaton, 2000.1.31, Meister and Braun, 1995.10, BDGP Project Members, 1994-1999, ) p50 (Sumegi et al., 2003, Kurucz et al., 2002, Holzl et al., 2000, Hoelzl, 1999.4.23, Ma et al., 2002) Pros26S (Spradling et al., 1999) Pros26S-RS6A (Misra, 2000.8.11, ) Rpt5 (Boutros et al., 2004, Boutros et al., 2004, Barbash and Lorigan, 2007, Ma et al., 2002) tbp-1 (Qin et al., 2005) Tbp1 (Orian et al., 2003) Tbp-1 (Hoopfer et al., 2008, Buszczak et al., 2007, White et al., 2011, Christensen et al., 2008.4.15, Christensen et al., 2008.4.15, Slack et al., 2007, Chittaranjan et al., 2009, Barbash and Lorigan, 2007, Zhou et al., 2008, Liu and Lehmann, 2008, Franco et al., 2011) TBP-1 (Ma et al., 2002)
Name Synonym	Proteasome 26S regulatory subunit 6A (Spradling et al., 1999) Tat-binding protein-1
Secondary FlyBase IDs
	FBgn0010835 FBgn0026321 FBgn0027925 FBgn0045868 FBgn0045870 FBgn0045946
References ( 48 )
Generate a list of	All references relating to this gene ( 48 )
List References by type	Research paper  ( 21 ) Supplementary material  ( 3 ) Review  ( 1 ) Personal communication to FlyBase  ( 11 ) FlyBase analysis  ( 2 ) DNA/RNA sequence record  ( 3 ) Computer file  ( 4 ) Curated genome annotation  ( 1 ) Automatic genome annotation  ( 1 ) Patent  ( 1 )
Recent research papers ( 4 )
	Booker et al., 2011, BMC Genomics 12: 50 False negative rates in Drosophila cell-based RNAi screens: a case study. [FBrf0212969] Franco et al., 2011, Mol. Cell. Proteomics 10(5): M110.002188 A Novel Strategy to Isolate Ubiquitin Conjugates Reveals Wide Role for Ubiquitination during Neural Development. [FBrf0213919] White et al., 2011, J. Cell Biol. 193(4): 677--694 Drosophila histone locus bodies form by hierarchical recruitment of components. [FBrf0213662] Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...