Gene Dmel\Rpt1

Comment:maternally deposited

embryonic stage 4 -- 6

organism

embryonic stage 7 -- 8

organism | ubiquitous

embryonic stage 9 -- 10

organism | ubiquitous

embryonic stage 11 -- 12

organism | ubiquitous

embryonic stage 13 -- 16

organism | ubiquitous

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

proteasome regulatory particle

References

inferred from direct assay

(Sumegi et al., 2003)

inferred from direct assay AND inferred from sequence or structural similarity with human PSMC2

(Holzl et al., 2000)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: High levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval/adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		1009.775
Larval Midgut		1524.5
Larval Hindgut		1311.9
Larval Malpighian Tubules		2442.4
Larval Fat Body		1318.7
Larval Salivary Gland		1521.3
Larval Trachea		1251.025
Larval Carcass		1811.525
Adult Head		584.7
Adult Eye		646.625
Adult Brain		526.6
Adult Thoracic-Abdominal Ganglion		547.6
Adult Crop		956.5
Adult Midgut		809.4
Adult Hindgut		691.1
Adult Malpighian Tubules		1142.9
Adult Fat Body		1263.7
Adult Salivary Gland		812.3
Adult Heart		1509.525
Adult VirginFemale Spermatheca		1393
Adult InseminatedFemale Spermatheca		1336.8
Adult Ovary		1139.5
Adult Testis		619.3
Adult Male Accessory Gland		587.9
Adult Carcass		1016.6
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		(1009.775)
Larval Midgut		(1524.5)
Larval Hindgut		(1311.9)
Larval Malpighian Tubules		(2442.4)
Larval Fat Body		(1318.7)
Larval Salivary Gland		(1521.3)
Larval Trachea		(1251.025)
Larval Carcass		(1811.525)
Adult Head		(584.7)
Adult Eye		(646.625)
Adult Brain		526.6
Adult Thoracic-Abdominal Ganglion		(547.6)
Adult Crop		(956.5)
Adult Midgut		(809.4)
Adult Hindgut		(691.1)
Adult Malpighian Tubules		(1142.9)
Adult Fat Body		(1263.7)
Adult Salivary Gland		(812.3)
Adult Heart		(1509.525)
Adult VirginFemale Spermatheca		(1393)
Adult InseminatedFemale Spermatheca		(1336.8)
Adult Ovary		(1139.5)
Adult Testis		(619.3)
Adult Male Accessory Gland		(587.9)
Adult Carcass		(1016.6)
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		1009.775
Larval Midgut		(1524.5)
Larval Hindgut		(1311.9)
Larval Malpighian Tubules		(2442.4)
Larval Fat Body		(1318.7)
Larval Salivary Gland		(1521.3)
Larval Trachea		(1251.025)
Larval Carcass		(1811.525)
Adult Head		584.7
Adult Eye		646.625
Adult Brain		526.6
Adult Thoracic-Abdominal Ganglion		547.6
Adult Crop		956.5
Adult Midgut		809.4
Adult Hindgut		691.1
Adult Malpighian Tubules		(1142.9)
Adult Fat Body		(1263.7)
Adult Salivary Gland		812.3
Adult Heart		(1509.525)
Adult VirginFemale Spermatheca		(1393)
Adult InseminatedFemale Spermatheca		(1336.8)
Adult Ovary		(1139.5)
Adult Testis		619.3
Adult Male Accessory Gland		587.9
Adult Carcass		1016.6
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		1009.775
Larval Midgut		1524.5
Larval Hindgut		1311.9
Larval Malpighian Tubules		2442.4
Larval Fat Body		1318.7
Larval Salivary Gland		1521.3
Larval Trachea		1251.025
Larval Carcass		1811.525
Adult Head		584.7
Adult Eye		646.625
Adult Brain		526.6
Adult Thoracic-Abdominal Ganglion		547.6
Adult Crop		956.5
Adult Midgut		809.4
Adult Hindgut		691.1
Adult Malpighian Tubules		1142.9
Adult Fat Body		1263.7
Adult Salivary Gland		812.3
Adult Heart		1509.525
Adult VirginFemale Spermatheca		1393
Adult InseminatedFemale Spermatheca		1336.8
Adult Ovary		1139.5
Adult Testis		619.3
Adult Male Accessory Gland		587.9
Adult Carcass		1016.6
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		1009.775
Larval Midgut		1524.5
Larval Hindgut		1311.9
Larval Malpighian Tubules		2442.4
Larval Fat Body		1318.7
Larval Salivary Gland		1521.3
Larval Trachea		1251.025
Larval Carcass		1811.525
Adult Head		584.7
Adult Eye		646.625
Adult Brain		526.6
Adult Thoracic-Abdominal Ganglion		547.6
Adult Crop		956.5
Adult Midgut		809.4
Adult Hindgut		691.1
Adult Malpighian Tubules		1142.9
Adult Fat Body		1263.7
Adult Salivary Gland		812.3
Adult Heart		1509.525
Adult VirginFemale Spermatheca		1393
Adult InseminatedFemale Spermatheca		1336.8
Adult Ovary		1139.5
Adult Testis		619.3
Adult Male Accessory Gland		587.9
Adult Carcass		1016.6
Expression Level Scale		None Low Moderate High Very high

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		(1009.775)
Larval Midgut		(1524.5)
Larval Hindgut		(1311.9)
Larval Malpighian Tubules		(2442.4)
Larval Fat Body		(1318.7)
Larval Salivary Gland		(1521.3)
Larval Trachea		(1251.025)
Larval Carcass		(1811.525)
Adult Head		584.7
Adult Eye		646.625
Adult Brain		526.6
Adult Thoracic-Abdominal Ganglion		547.6
Adult Crop		(956.5)
Adult Midgut		809.4
Adult Hindgut		691.1
Adult Malpighian Tubules		(1142.9)
Adult Fat Body		(1263.7)
Adult Salivary Gland		812.3
Adult Heart		(1509.525)
Adult VirginFemale Spermatheca		(1393)
Adult InseminatedFemale Spermatheca		(1336.8)
Adult Ovary		(1139.5)
Adult Testis		619.3
Adult Male Accessory Gland		587.9
Adult Carcass		(1016.6)
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		1009.775
Larval Midgut		1524.5
Larval Hindgut		1311.9
Larval Malpighian Tubules		(2442.4)
Larval Fat Body		1318.7
Larval Salivary Gland		1521.3
Larval Trachea		1251.025
Larval Carcass		(1811.525)
Adult Head		584.7
Adult Eye		646.625
Adult Brain		526.6
Adult Thoracic-Abdominal Ganglion		547.6
Adult Crop		956.5
Adult Midgut		809.4
Adult Hindgut		691.1
Adult Malpighian Tubules		1142.9
Adult Fat Body		1263.7
Adult Salivary Gland		812.3
Adult Heart		1509.525
Adult VirginFemale Spermatheca		1393
Adult InseminatedFemale Spermatheca		1336.8
Adult Ovary		1139.5
Adult Testis		619.3
Adult Male Accessory Gland		587.9
Adult Carcass		1016.6
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		1009.775
Larval Midgut		1524.5
Larval Hindgut		1311.9
Larval Malpighian Tubules		2442.4
Larval Fat Body		1318.7
Larval Salivary Gland		1521.3
Larval Trachea		1251.025
Larval Carcass		1811.525
Adult Head		584.7
Adult Eye		646.625
Adult Brain		526.6
Adult Thoracic-Abdominal Ganglion		547.6
Adult Crop		956.5
Adult Midgut		809.4
Adult Hindgut		691.1
Adult Malpighian Tubules		1142.9
Adult Fat Body		1263.7
Adult Salivary Gland		812.3
Adult Heart		1509.525
Adult VirginFemale Spermatheca		1393
Adult InseminatedFemale Spermatheca		1336.8
Adult Ovary		1139.5
Adult Testis		619.3
Adult Male Accessory Gland		587.9
Adult Carcass		1016.6
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	584.7
NA	Eye	646.625
NA	Brain	526.6
1009.775	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	547.6
NA	Crop	956.5
1524.5	Midgut	809.4
1311.9	Hindgut	691.1
2442.4	Malpighian Tubules	1142.9
1318.7	Fat Body	1263.7
1521.3	Salivary Gland	812.3
NA	Heart	1509.525
1251.025	Trachea	NA
NA	VirginFemale Spermatheca	1393
NA	InseminatedFemale Spermatheca	1336.8
NA	Ovary	1139.5
NA	Testis	619.3
NA	Male Accessory Gland	587.9
1811.525	Carcass	1016.6

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		100
central nervous system, larvae L3		95
central nervous system, pupae P8		39
head, virgin 1-day female		33
head, virgin 4-day female		28
head, virgin 20-day female		25
head, mated 1-day female		30
head, mated 4-day female		25
head, mated 20-day female		28
head, mated 1-day male		39
head, mated 4-day male		35
head, mated 20-day male		53
salivary gland, larvae L3 wandering		30
salivary gland, white prepupae		91
digestive system, larvae L3 wandering		283
digestive system, 1-day adult		42
digestive system, 4-day adult		47
digestive system, 20-day adult		44
fat body, larvae L3 wandering		28
fat body, white prepupae		102
fat body, pupae P8		47
carcass, larvae L3 wandering		219
carcass, 1-day adult		44
carcass, 4-day adult		52
carcass, 20-day adult		49
ovary, virgin 4-day female		127
ovary, mated 4-day female		152
testis, mated 4-day male		102
accessory gland, mated 4-day male		40
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(100)
central nervous system, larvae L3		(95)
central nervous system, pupae P8		(39)
head, virgin 1-day female		(33)
head, virgin 4-day female		(28)
head, virgin 20-day female		25
head, mated 1-day female		(30)
head, mated 4-day female		25
head, mated 20-day female		(28)
head, mated 1-day male		(39)
head, mated 4-day male		(35)
head, mated 20-day male		(53)
salivary gland, larvae L3 wandering		(30)
salivary gland, white prepupae		(91)
digestive system, larvae L3 wandering		(283)
digestive system, 1-day adult		(42)
digestive system, 4-day adult		(47)
digestive system, 20-day adult		(44)
fat body, larvae L3 wandering		(28)
fat body, white prepupae		(102)
fat body, pupae P8		(47)
carcass, larvae L3 wandering		(219)
carcass, 1-day adult		(44)
carcass, 4-day adult		(52)
carcass, 20-day adult		(49)
ovary, virgin 4-day female		(127)
ovary, mated 4-day female		(152)
testis, mated 4-day male		(102)
accessory gland, mated 4-day male		(40)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		100
central nervous system, larvae L3		95
central nervous system, pupae P8		39
head, virgin 1-day female		33
head, virgin 4-day female		28
head, virgin 20-day female		25
head, mated 1-day female		30
head, mated 4-day female		25
head, mated 20-day female		28
head, mated 1-day male		39
head, mated 4-day male		35
head, mated 20-day male		53
salivary gland, larvae L3 wandering		30
salivary gland, white prepupae		91
digestive system, larvae L3 wandering		(283)
digestive system, 1-day adult		42
digestive system, 4-day adult		47
digestive system, 20-day adult		44
fat body, larvae L3 wandering		28
fat body, white prepupae		102
fat body, pupae P8		47
carcass, larvae L3 wandering		(219)
carcass, 1-day adult		44
carcass, 4-day adult		52
carcass, 20-day adult		49
ovary, virgin 4-day female		(127)
ovary, mated 4-day female		(152)
testis, mated 4-day male		102
accessory gland, mated 4-day male		40
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		100
central nervous system, larvae L3		95
central nervous system, pupae P8		39
head, virgin 1-day female		33
head, virgin 4-day female		28
head, virgin 20-day female		25
head, mated 1-day female		30
head, mated 4-day female		25
head, mated 20-day female		28
head, mated 1-day male		39
head, mated 4-day male		35
head, mated 20-day male		53
salivary gland, larvae L3 wandering		30
salivary gland, white prepupae		91
digestive system, larvae L3 wandering		283
digestive system, 1-day adult		42
digestive system, 4-day adult		47
digestive system, 20-day adult		44
fat body, larvae L3 wandering		28
fat body, white prepupae		102
fat body, pupae P8		47
carcass, larvae L3 wandering		219
carcass, 1-day adult		44
carcass, 4-day adult		52
carcass, 20-day adult		49
ovary, virgin 4-day female		127
ovary, mated 4-day female		152
testis, mated 4-day male		102
accessory gland, mated 4-day male		40
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		100
central nervous system, larvae L3		95
central nervous system, pupae P8		39
head, virgin 1-day female		33
head, virgin 4-day female		28
head, virgin 20-day female		25
head, mated 1-day female		30
head, mated 4-day female		25
head, mated 20-day female		28
head, mated 1-day male		39
head, mated 4-day male		35
head, mated 20-day male		53
salivary gland, larvae L3 wandering		30
salivary gland, white prepupae		91
digestive system, larvae L3 wandering		283
digestive system, 1-day adult		42
digestive system, 4-day adult		47
digestive system, 20-day adult		44
fat body, larvae L3 wandering		28
fat body, white prepupae		102
fat body, pupae P8		47
carcass, larvae L3 wandering		219
carcass, 1-day adult		44
carcass, 4-day adult		52
carcass, 20-day adult		49
ovary, virgin 4-day female		127
ovary, mated 4-day female		152
testis, mated 4-day male		102
accessory gland, mated 4-day male		40
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(100)
central nervous system, larvae L3		(95)
central nervous system, pupae P8		(39)
head, virgin 1-day female		(33)
head, virgin 4-day female		28
head, virgin 20-day female		25
head, mated 1-day female		30
head, mated 4-day female		25
head, mated 20-day female		28
head, mated 1-day male		(39)
head, mated 4-day male		(35)
head, mated 20-day male		(53)
salivary gland, larvae L3 wandering		30
salivary gland, white prepupae		(91)
digestive system, larvae L3 wandering		(283)
digestive system, 1-day adult		(42)
digestive system, 4-day adult		(47)
digestive system, 20-day adult		(44)
fat body, larvae L3 wandering		28
fat body, white prepupae		(102)
fat body, pupae P8		(47)
carcass, larvae L3 wandering		(219)
carcass, 1-day adult		(44)
carcass, 4-day adult		(52)
carcass, 20-day adult		(49)
ovary, virgin 4-day female		(127)
ovary, mated 4-day female		(152)
testis, mated 4-day male		(102)
accessory gland, mated 4-day male		(40)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		100
central nervous system, larvae L3		95
central nervous system, pupae P8		39
head, virgin 1-day female		33
head, virgin 4-day female		28
head, virgin 20-day female		25
head, mated 1-day female		30
head, mated 4-day female		25
head, mated 20-day female		28
head, mated 1-day male		39
head, mated 4-day male		35
head, mated 20-day male		53
salivary gland, larvae L3 wandering		30
salivary gland, white prepupae		91
digestive system, larvae L3 wandering		(283)
digestive system, 1-day adult		42
digestive system, 4-day adult		47
digestive system, 20-day adult		44
fat body, larvae L3 wandering		28
fat body, white prepupae		102
fat body, pupae P8		47
carcass, larvae L3 wandering		(219)
carcass, 1-day adult		44
carcass, 4-day adult		52
carcass, 20-day adult		49
ovary, virgin 4-day female		127
ovary, mated 4-day female		(152)
testis, mated 4-day male		102
accessory gland, mated 4-day male		40
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		100
central nervous system, larvae L3		95
central nervous system, pupae P8		39
head, virgin 1-day female		33
head, virgin 4-day female		28
head, virgin 20-day female		25
head, mated 1-day female		30
head, mated 4-day female		25
head, mated 20-day female		28
head, mated 1-day male		39
head, mated 4-day male		35
head, mated 20-day male		53
salivary gland, larvae L3 wandering		30
salivary gland, white prepupae		91
digestive system, larvae L3 wandering		283
digestive system, 1-day adult		42
digestive system, 4-day adult		47
digestive system, 20-day adult		44
fat body, larvae L3 wandering		28
fat body, white prepupae		102
fat body, pupae P8		47
carcass, larvae L3 wandering		219
carcass, 1-day adult		44
carcass, 4-day adult		52
carcass, 20-day adult		49
ovary, virgin 4-day female		127
ovary, mated 4-day female		152
testis, mated 4-day male		102
accessory gland, mated 4-day male		40
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-12 hour embryonic stages, during late larval stages, at stages throughout the pupal period, in adult female stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		296
embryo 02-04hr		195
embryo 04-06hr		150
embryo 06-08hr		159
embryo 08-10hr		135
embryo 10-12hr		127
embryo 12-14hr		72
embryo 14-16hr		76
embryo 16-18hr		59
embryo 18-20hr		52
embryo 20-22hr		43
embryo 22-24hr		44
larva L1		69
larva L2		126
larva L3 12hr old		90
larva L3 puffstage 1-2		153
larva L3 puffstage 3-6		247
larva L3 puffstage 7-9		367
white prepupae new		429
white prepupae 12hr		185
white prepupae 24hr		174
pupae 2d postWPP		108
pupae 3d postWPP		88
pupae 4d postWPP		162
adult male 01day		121
adult male 05day		115
adult male 30day		116
adult female 01day		164
adult female 05day		187
adult female 30day		195
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(296)
embryo 02-04hr		(195)
embryo 04-06hr		(150)
embryo 06-08hr		(159)
embryo 08-10hr		(135)
embryo 10-12hr		(127)
embryo 12-14hr		(72)
embryo 14-16hr		(76)
embryo 16-18hr		(59)
embryo 18-20hr		(52)
embryo 20-22hr		(43)
embryo 22-24hr		(44)
larva L1		(69)
larva L2		(126)
larva L3 12hr old		(90)
larva L3 puffstage 1-2		(153)
larva L3 puffstage 3-6		(247)
larva L3 puffstage 7-9		(367)
white prepupae new		(429)
white prepupae 12hr		(185)
white prepupae 24hr		(174)
pupae 2d postWPP		(108)
pupae 3d postWPP		(88)
pupae 4d postWPP		(162)
adult male 01day		(121)
adult male 05day		(115)
adult male 30day		(116)
adult female 01day		(164)
adult female 05day		(187)
adult female 30day		(195)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		(296)
embryo 02-04hr		(195)
embryo 04-06hr		(150)
embryo 06-08hr		(159)
embryo 08-10hr		(135)
embryo 10-12hr		(127)
embryo 12-14hr		72
embryo 14-16hr		76
embryo 16-18hr		59
embryo 18-20hr		52
embryo 20-22hr		43
embryo 22-24hr		44
larva L1		69
larva L2		(126)
larva L3 12hr old		90
larva L3 puffstage 1-2		(153)
larva L3 puffstage 3-6		(247)
larva L3 puffstage 7-9		(367)
white prepupae new		(429)
white prepupae 12hr		(185)
white prepupae 24hr		(174)
pupae 2d postWPP		(108)
pupae 3d postWPP		88
pupae 4d postWPP		(162)
adult male 01day		(121)
adult male 05day		(115)
adult male 30day		(116)
adult female 01day		(164)
adult female 05day		(187)
adult female 30day		(195)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		296
embryo 02-04hr		195
embryo 04-06hr		150
embryo 06-08hr		159
embryo 08-10hr		135
embryo 10-12hr		127
embryo 12-14hr		72
embryo 14-16hr		76
embryo 16-18hr		59
embryo 18-20hr		52
embryo 20-22hr		43
embryo 22-24hr		44
larva L1		69
larva L2		126
larva L3 12hr old		90
larva L3 puffstage 1-2		153
larva L3 puffstage 3-6		247
larva L3 puffstage 7-9		367
white prepupae new		429
white prepupae 12hr		185
white prepupae 24hr		174
pupae 2d postWPP		108
pupae 3d postWPP		88
pupae 4d postWPP		162
adult male 01day		121
adult male 05day		115
adult male 30day		116
adult female 01day		164
adult female 05day		187
adult female 30day		195
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		296
embryo 02-04hr		195
embryo 04-06hr		150
embryo 06-08hr		159
embryo 08-10hr		135
embryo 10-12hr		127
embryo 12-14hr		72
embryo 14-16hr		76
embryo 16-18hr		59
embryo 18-20hr		52
embryo 20-22hr		43
embryo 22-24hr		44
larva L1		69
larva L2		126
larva L3 12hr old		90
larva L3 puffstage 1-2		153
larva L3 puffstage 3-6		247
larva L3 puffstage 7-9		367
white prepupae new		429
white prepupae 12hr		185
white prepupae 24hr		174
pupae 2d postWPP		108
pupae 3d postWPP		88
pupae 4d postWPP		162
adult male 01day		121
adult male 05day		115
adult male 30day		116
adult female 01day		164
adult female 05day		187
adult female 30day		195
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(296)
embryo 02-04hr		(195)
embryo 04-06hr		(150)
embryo 06-08hr		(159)
embryo 08-10hr		(135)
embryo 10-12hr		(127)
embryo 12-14hr		(72)
embryo 14-16hr		(76)
embryo 16-18hr		(59)
embryo 18-20hr		(52)
embryo 20-22hr		(43)
embryo 22-24hr		(44)
larva L1		(69)
larva L2		(126)
larva L3 12hr old		(90)
larva L3 puffstage 1-2		(153)
larva L3 puffstage 3-6		(247)
larva L3 puffstage 7-9		(367)
white prepupae new		(429)
white prepupae 12hr		(185)
white prepupae 24hr		(174)
pupae 2d postWPP		(108)
pupae 3d postWPP		(88)
pupae 4d postWPP		(162)
adult male 01day		(121)
adult male 05day		(115)
adult male 30day		(116)
adult female 01day		(164)
adult female 05day		(187)
adult female 30day		(195)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		(296)
embryo 02-04hr		(195)
embryo 04-06hr		(150)
embryo 06-08hr		(159)
embryo 08-10hr		135
embryo 10-12hr		127
embryo 12-14hr		72
embryo 14-16hr		76
embryo 16-18hr		59
embryo 18-20hr		52
embryo 20-22hr		43
embryo 22-24hr		44
larva L1		69
larva L2		126
larva L3 12hr old		90
larva L3 puffstage 1-2		(153)
larva L3 puffstage 3-6		(247)
larva L3 puffstage 7-9		(367)
white prepupae new		(429)
white prepupae 12hr		(185)
white prepupae 24hr		(174)
pupae 2d postWPP		108
pupae 3d postWPP		88
pupae 4d postWPP		(162)
adult male 01day		121
adult male 05day		115
adult male 30day		116
adult female 01day		(164)
adult female 05day		(187)
adult female 30day		(195)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		296
embryo 02-04hr		195
embryo 04-06hr		150
embryo 06-08hr		159
embryo 08-10hr		135
embryo 10-12hr		127
embryo 12-14hr		72
embryo 14-16hr		76
embryo 16-18hr		59
embryo 18-20hr		52
embryo 20-22hr		43
embryo 22-24hr		44
larva L1		69
larva L2		126
larva L3 12hr old		90
larva L3 puffstage 1-2		153
larva L3 puffstage 3-6		247
larva L3 puffstage 7-9		367
white prepupae new		429
white prepupae 12hr		185
white prepupae 24hr		174
pupae 2d postWPP		108
pupae 3d postWPP		88
pupae 4d postWPP		162
adult male 01day		121
adult male 05day		115
adult male 30day		116
adult female 01day		164
adult female 05day		187
adult female 30day		195
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		319
Schneider line 2 Sg4		150
embryonic 1182-4H		92
embryonic GM2		105
embryonic Kc167		78
embryonic S1		149
embryonic S3		84
leg disc CME L1		115
wing disc CME-W2		85
wing disc ML-DmD8		103
wing disc ML-DmD9		113
wing disc ML-DmD16-c3		158
wing disc ML-DmD21		167
wing disc ML-DmD32		114
haltere disc ML-DmD17-c3		121
eye-antennal disc ML-DmD11		85
antennal disc ML-DmD20-c5		111
mixed discs ML-DmD4-c1		136
CNS ML-DmBG1-c1		117
CNS ML-DmBG2-c2		185
tumorous blood cells mbn2		80
ovary fGS/OSS		160
ovary OSC		177
ovary OSS		115
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(319)
Schneider line 2 Sg4		(150)
embryonic 1182-4H		(92)
embryonic GM2		(105)
embryonic Kc167		(78)
embryonic S1		(149)
embryonic S3		(84)
leg disc CME L1		(115)
wing disc CME-W2		(85)
wing disc ML-DmD8		(103)
wing disc ML-DmD9		(113)
wing disc ML-DmD16-c3		(158)
wing disc ML-DmD21		(167)
wing disc ML-DmD32		(114)
haltere disc ML-DmD17-c3		(121)
eye-antennal disc ML-DmD11		(85)
antennal disc ML-DmD20-c5		(111)
mixed discs ML-DmD4-c1		(136)
CNS ML-DmBG1-c1		(117)
CNS ML-DmBG2-c2		(185)
tumorous blood cells mbn2		(80)
ovary fGS/OSS		(160)
ovary OSC		(177)
ovary OSS		(115)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		(319)
Schneider line 2 Sg4		(150)
embryonic 1182-4H		92
embryonic GM2		105
embryonic Kc167		78
embryonic S1		(149)
embryonic S3		84
leg disc CME L1		(115)
wing disc CME-W2		85
wing disc ML-DmD8		103
wing disc ML-DmD9		(113)
wing disc ML-DmD16-c3		(158)
wing disc ML-DmD21		(167)
wing disc ML-DmD32		(114)
haltere disc ML-DmD17-c3		(121)
eye-antennal disc ML-DmD11		85
antennal disc ML-DmD20-c5		(111)
mixed discs ML-DmD4-c1		(136)
CNS ML-DmBG1-c1		(117)
CNS ML-DmBG2-c2		(185)
tumorous blood cells mbn2		80
ovary fGS/OSS		(160)
ovary OSC		(177)
ovary OSS		(115)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		319
Schneider line 2 Sg4		150
embryonic 1182-4H		92
embryonic GM2		105
embryonic Kc167		78
embryonic S1		149
embryonic S3		84
leg disc CME L1		115
wing disc CME-W2		85
wing disc ML-DmD8		103
wing disc ML-DmD9		113
wing disc ML-DmD16-c3		158
wing disc ML-DmD21		167
wing disc ML-DmD32		114
haltere disc ML-DmD17-c3		121
eye-antennal disc ML-DmD11		85
antennal disc ML-DmD20-c5		111
mixed discs ML-DmD4-c1		136
CNS ML-DmBG1-c1		117
CNS ML-DmBG2-c2		185
tumorous blood cells mbn2		80
ovary fGS/OSS		160
ovary OSC		177
ovary OSS		115
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		319
Schneider line 2 Sg4		150
embryonic 1182-4H		92
embryonic GM2		105
embryonic Kc167		78
embryonic S1		149
embryonic S3		84
leg disc CME L1		115
wing disc CME-W2		85
wing disc ML-DmD8		103
wing disc ML-DmD9		113
wing disc ML-DmD16-c3		158
wing disc ML-DmD21		167
wing disc ML-DmD32		114
haltere disc ML-DmD17-c3		121
eye-antennal disc ML-DmD11		85
antennal disc ML-DmD20-c5		111
mixed discs ML-DmD4-c1		136
CNS ML-DmBG1-c1		117
CNS ML-DmBG2-c2		185
tumorous blood cells mbn2		80
ovary fGS/OSS		160
ovary OSC		177
ovary OSS		115
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(319)
Schneider line 2 Sg4		(150)
embryonic 1182-4H		(92)
embryonic GM2		(105)
embryonic Kc167		(78)
embryonic S1		(149)
embryonic S3		(84)
leg disc CME L1		(115)
wing disc CME-W2		(85)
wing disc ML-DmD8		(103)
wing disc ML-DmD9		(113)
wing disc ML-DmD16-c3		(158)
wing disc ML-DmD21		(167)
wing disc ML-DmD32		(114)
haltere disc ML-DmD17-c3		(121)
eye-antennal disc ML-DmD11		(85)
antennal disc ML-DmD20-c5		(111)
mixed discs ML-DmD4-c1		(136)
CNS ML-DmBG1-c1		(117)
CNS ML-DmBG2-c2		(185)
tumorous blood cells mbn2		(80)
ovary fGS/OSS		(160)
ovary OSC		(177)
ovary OSS		(115)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		(319)
Schneider line 2 Sg4		(150)
embryonic 1182-4H		92
embryonic GM2		105
embryonic Kc167		78
embryonic S1		(149)
embryonic S3		84
leg disc CME L1		115
wing disc CME-W2		85
wing disc ML-DmD8		103
wing disc ML-DmD9		113
wing disc ML-DmD16-c3		(158)
wing disc ML-DmD21		(167)
wing disc ML-DmD32		114
haltere disc ML-DmD17-c3		121
eye-antennal disc ML-DmD11		85
antennal disc ML-DmD20-c5		111
mixed discs ML-DmD4-c1		136
CNS ML-DmBG1-c1		117
CNS ML-DmBG2-c2		(185)
tumorous blood cells mbn2		80
ovary fGS/OSS		(160)
ovary OSC		(177)
ovary OSS		115
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		319
Schneider line 2 Sg4		150
embryonic 1182-4H		92
embryonic GM2		105
embryonic Kc167		78
embryonic S1		149
embryonic S3		84
leg disc CME L1		115
wing disc CME-W2		85
wing disc ML-DmD8		103
wing disc ML-DmD9		113
wing disc ML-DmD16-c3		158
wing disc ML-DmD21		167
wing disc ML-DmD32		114
haltere disc ML-DmD17-c3		121
eye-antennal disc ML-DmD11		85
antennal disc ML-DmD20-c5		111
mixed discs ML-DmD4-c1		136
CNS ML-DmBG1-c1		117
CNS ML-DmBG2-c2		185
tumorous blood cells mbn2		80
ovary fGS/OSS		160
ovary OSC		177
ovary OSS		115
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		82
cold shock, 4-day adult		69
heat shock, 4-day adult		86
Cadmium 50 mM 6 hrs, larvae L3		86
Cadmium 50 mM 12 hrs, larvae L3		116
Cadmium 50 mM 48 hrs, 4-day adult		77
Cadmium 100 mM 48 hrs, 4-day adult		102
Copper 0.5 mM 12 hrs, larvae L3		114
Copper 15 mM 48 hrs, 4-day adult		126
Zinc 5 mM 12 hrs, larvae L3		78
Zinc 4.5 mM 48 hrs, 4-day adult		61
Ethanol 2.5% 3 hrs, larvae L3		102
Ethanol 5% 3 hrs, larvae L3		63
Ethanol 10% 3 hrs, larvae L3		56
Caffeine 1.5 mg/ml 4 hrs, larvae L3		72
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		114
Caffeine 25 mg/ml 48 hrs, 4-day adult		70
Paraquat 5 mM 48 hrs, 4-day adult		95
Paraquat 10 mM 48 hrs, 4-day adult		104
Rotenone 2 μg 12 hrs, larvae L3		75
Rotenone 8 μg 12 hrs, larvae L3		57
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		(82)
cold shock, 4-day adult		(69)
heat shock, 4-day adult		(86)
Cadmium 50 mM 6 hrs, larvae L3		(86)
Cadmium 50 mM 12 hrs, larvae L3		(116)
Cadmium 50 mM 48 hrs, 4-day adult		(77)
Cadmium 100 mM 48 hrs, 4-day adult		(102)
Copper 0.5 mM 12 hrs, larvae L3		(114)
Copper 15 mM 48 hrs, 4-day adult		(126)
Zinc 5 mM 12 hrs, larvae L3		(78)
Zinc 4.5 mM 48 hrs, 4-day adult		(61)
Ethanol 2.5% 3 hrs, larvae L3		(102)
Ethanol 5% 3 hrs, larvae L3		(63)
Ethanol 10% 3 hrs, larvae L3		(56)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(72)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(114)
Caffeine 25 mg/ml 48 hrs, 4-day adult		(70)
Paraquat 5 mM 48 hrs, 4-day adult		(95)
Paraquat 10 mM 48 hrs, 4-day adult		(104)
Rotenone 2 μg 12 hrs, larvae L3		(75)
Rotenone 8 μg 12 hrs, larvae L3		(57)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		82
cold shock, 4-day adult		69
heat shock, 4-day adult		86
Cadmium 50 mM 6 hrs, larvae L3		86
Cadmium 50 mM 12 hrs, larvae L3		(116)
Cadmium 50 mM 48 hrs, 4-day adult		77
Cadmium 100 mM 48 hrs, 4-day adult		102
Copper 0.5 mM 12 hrs, larvae L3		(114)
Copper 15 mM 48 hrs, 4-day adult		(126)
Zinc 5 mM 12 hrs, larvae L3		78
Zinc 4.5 mM 48 hrs, 4-day adult		61
Ethanol 2.5% 3 hrs, larvae L3		102
Ethanol 5% 3 hrs, larvae L3		63
Ethanol 10% 3 hrs, larvae L3		56
Caffeine 1.5 mg/ml 4 hrs, larvae L3		72
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(114)
Caffeine 25 mg/ml 48 hrs, 4-day adult		70
Paraquat 5 mM 48 hrs, 4-day adult		95
Paraquat 10 mM 48 hrs, 4-day adult		104
Rotenone 2 μg 12 hrs, larvae L3		75
Rotenone 8 μg 12 hrs, larvae L3		57
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		82
cold shock, 4-day adult		69
heat shock, 4-day adult		86
Cadmium 50 mM 6 hrs, larvae L3		86
Cadmium 50 mM 12 hrs, larvae L3		116
Cadmium 50 mM 48 hrs, 4-day adult		77
Cadmium 100 mM 48 hrs, 4-day adult		102
Copper 0.5 mM 12 hrs, larvae L3		114
Copper 15 mM 48 hrs, 4-day adult		126
Zinc 5 mM 12 hrs, larvae L3		78
Zinc 4.5 mM 48 hrs, 4-day adult		61
Ethanol 2.5% 3 hrs, larvae L3		102
Ethanol 5% 3 hrs, larvae L3		63
Ethanol 10% 3 hrs, larvae L3		56
Caffeine 1.5 mg/ml 4 hrs, larvae L3		72
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		114
Caffeine 25 mg/ml 48 hrs, 4-day adult		70
Paraquat 5 mM 48 hrs, 4-day adult		95
Paraquat 10 mM 48 hrs, 4-day adult		104
Rotenone 2 μg 12 hrs, larvae L3		75
Rotenone 8 μg 12 hrs, larvae L3		57
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		82
cold shock, 4-day adult		69
heat shock, 4-day adult		86
Cadmium 50 mM 6 hrs, larvae L3		86
Cadmium 50 mM 12 hrs, larvae L3		116
Cadmium 50 mM 48 hrs, 4-day adult		77
Cadmium 100 mM 48 hrs, 4-day adult		102
Copper 0.5 mM 12 hrs, larvae L3		114
Copper 15 mM 48 hrs, 4-day adult		126
Zinc 5 mM 12 hrs, larvae L3		78
Zinc 4.5 mM 48 hrs, 4-day adult		61
Ethanol 2.5% 3 hrs, larvae L3		102
Ethanol 5% 3 hrs, larvae L3		63
Ethanol 10% 3 hrs, larvae L3		56
Caffeine 1.5 mg/ml 4 hrs, larvae L3		72
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		114
Caffeine 25 mg/ml 48 hrs, 4-day adult		70
Paraquat 5 mM 48 hrs, 4-day adult		95
Paraquat 10 mM 48 hrs, 4-day adult		104
Rotenone 2 μg 12 hrs, larvae L3		75
Rotenone 8 μg 12 hrs, larvae L3		57
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		(82)
cold shock, 4-day adult		(69)
heat shock, 4-day adult		(86)
Cadmium 50 mM 6 hrs, larvae L3		(86)
Cadmium 50 mM 12 hrs, larvae L3		(116)
Cadmium 50 mM 48 hrs, 4-day adult		(77)
Cadmium 100 mM 48 hrs, 4-day adult		(102)
Copper 0.5 mM 12 hrs, larvae L3		(114)
Copper 15 mM 48 hrs, 4-day adult		(126)
Zinc 5 mM 12 hrs, larvae L3		(78)
Zinc 4.5 mM 48 hrs, 4-day adult		(61)
Ethanol 2.5% 3 hrs, larvae L3		(102)
Ethanol 5% 3 hrs, larvae L3		(63)
Ethanol 10% 3 hrs, larvae L3		(56)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(72)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(114)
Caffeine 25 mg/ml 48 hrs, 4-day adult		(70)
Paraquat 5 mM 48 hrs, 4-day adult		(95)
Paraquat 10 mM 48 hrs, 4-day adult		(104)
Rotenone 2 μg 12 hrs, larvae L3		(75)
Rotenone 8 μg 12 hrs, larvae L3		(57)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		82
cold shock, 4-day adult		69
heat shock, 4-day adult		86
Cadmium 50 mM 6 hrs, larvae L3		86
Cadmium 50 mM 12 hrs, larvae L3		116
Cadmium 50 mM 48 hrs, 4-day adult		77
Cadmium 100 mM 48 hrs, 4-day adult		102
Copper 0.5 mM 12 hrs, larvae L3		114
Copper 15 mM 48 hrs, 4-day adult		126
Zinc 5 mM 12 hrs, larvae L3		78
Zinc 4.5 mM 48 hrs, 4-day adult		61
Ethanol 2.5% 3 hrs, larvae L3		102
Ethanol 5% 3 hrs, larvae L3		63
Ethanol 10% 3 hrs, larvae L3		56
Caffeine 1.5 mg/ml 4 hrs, larvae L3		72
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		114
Caffeine 25 mg/ml 48 hrs, 4-day adult		70
Paraquat 5 mM 48 hrs, 4-day adult		95
Paraquat 10 mM 48 hrs, 4-day adult		104
Rotenone 2 μg 12 hrs, larvae L3		75
Rotenone 8 μg 12 hrs, larvae L3		57
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		82
cold shock, 4-day adult		69
heat shock, 4-day adult		86
Cadmium 50 mM 6 hrs, larvae L3		86
Cadmium 50 mM 12 hrs, larvae L3		116
Cadmium 50 mM 48 hrs, 4-day adult		77
Cadmium 100 mM 48 hrs, 4-day adult		102
Copper 0.5 mM 12 hrs, larvae L3		114
Copper 15 mM 48 hrs, 4-day adult		126
Zinc 5 mM 12 hrs, larvae L3		78
Zinc 4.5 mM 48 hrs, 4-day adult		61
Ethanol 2.5% 3 hrs, larvae L3		102
Ethanol 5% 3 hrs, larvae L3		63
Ethanol 10% 3 hrs, larvae L3		56
Caffeine 1.5 mg/ml 4 hrs, larvae L3		72
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		114
Caffeine 25 mg/ml 48 hrs, 4-day adult		70
Paraquat 5 mM 48 hrs, 4-day adult		95
Paraquat 10 mM 48 hrs, 4-day adult		104
Rotenone 2 μg 12 hrs, larvae L3		75
Rotenone 8 μg 12 hrs, larvae L3		57
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

SD07148

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0028687

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG1341-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

lethal, with Scer\GAL4^pnr-MD237

Rpt1^GD8016

lethal | pupal stage, with Scer\GAL4^pnr-MD237

Rpt1^GD8016

lethal | recessive

Other Phenotypes

Allele

neuroanatomy defective | larval stage, with Scer\GAL4^elav-C155

Rpt1^EP2153

Phenotype manifest in

Allele

anterior fascicle & synapse, with Scer\GAL4^elav-C155

Rpt1^EP2153

intersegmental nerve, with Scer\GAL4^elav-C155

Rpt1^EP2153

Classical Alleles ( 5 )

For All Classical Alleles Show

Allele of Rpt1	Mutagen	Stocks	Known lesion
Rpt1^k11110	P-element activity	2	--
Rpt1⁰⁵⁶⁴³	P-element activity	1	Yes
Rpt1^43Ed-1	ethyl methanesulfonate	1	--
Rpt1^EP2153	P-element activity	1	Yes
Rpt1^k07513	P-element activity	1	--

Alleles Carried on Transgenic Constructs ( 4 )

For All Alleles Carried on Transgenic Constructs Show

Allele of Rpt1	Mutagen	Stocks	Known lesion
Rpt1^GD8016	in vitro construct - RNAi in vitro construct - regulatory fusion	3	Yes
Rpt1^HMS00879	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
Rpt1^dsRNA.cWa	in vitro construct - RNAi	0	Yes
Rpt1^KK100292	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Disrupted in

Df(2R)cn9

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Df(2R)cn-S5

Df(2R)cn-S6

Df(2R)cn-S8

Df(2R)Drl^rv5

Df(2R)Drl^rv7

Df(2R)Drl^rv18

Df(2R)Drl^rv21

Df(2R)Drl^rv24

Df(2R)Drl^rv26

Df(2R)Drl^rv30

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Df(2R)Exel6053

(Ryder, 2004.4.26)

Df(2R)Exel7092

(Ryder, 2004.4.26)

Df(2R)nap16

Df(2R)NCX8

(Eeken et al., 2001, Heitzler et al., 1993)

Df(2R)NCX9

Df(2R)NCX11

(Roote and Ashburner, 2005.6)

Df(2R)NCX13

(Eeken et al., 2001)

Df(2R)Npk-rv1

Df(2R)pk78s

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Df(2R)sple-N3

(Eeken et al., 2001, BDGP Project Members, 1994-1999)

Df(2R)ST1

Not disrupted in

Df(2R)CA53

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Df(2R)cos-2

Df(2R)cos-3

Df(2R)Drl^rv3

Df(2R)Drl^rv15

Df(2R)Drl^rv17

Df(2R)Drl^rv20

Df(2R)Drl^rv22

Df(2R)Drl^rv25

Df(2R)Drl^rv28

Df(2R)DX1

Df(2R)DX14

Df(2R)EW60

Df(2R)H23

Df(2R)nap2

Df(2R)NCX5

Df(2R)NCX10

Df(2R)pk-N5

Df(2R)pwn5

Df(2R)sple-D1

Df(2R)sple-D2

Df(2R)sple-D3

Df(2R)sple-J1

Df(2R)sple-J2

In(2LR)pkD1-rv11

(Roote, 1997.6.6)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD8016}

P{KK100292}

P{TRiP.HMS00879}

Insertions

Type of insertions

Name

Expression data

insertion of mobile activating element

P{EP}Rpt1^EP2153

insertion of enhancer trap

P{lacW}l(2)SH0675^SH0675

P{lacW}Rpt1^k07513

P{lacW}Rpt1^k11110

P{PZ}Rpt1⁰⁵⁶⁴³

Gene Ontology: Function, Process & Cellular Component ( 11 unique terms )

Terms Based on Experimental Evidence ( 5 terms )

Molecular Function

CV term

References

contributes_to
endopeptidase activity

inferred from direct assay

(Holzl et al., 2000)

Biological Process

CV term

response to DNA damage stimulus

References

cellular process

inferred from mutant phenotype

(Boutros et al., 2004)

proteolysis

inferred from direct assay AND inferred from sequence or structural similarity with human PSMC2 AND inferred from sequence or structural similarity with Saccharomyces RPT1

(Holzl et al., 2000)

inferred from mutant phenotype

(Ravi et al., 2009)

Cellular Component

CV term