A Database of Drosophila Genes & Genomes

FB2012_01, released January 20th, 2012
 

Gene Dmel\Rpn11

General Information
SymbolDmel\Rpn11SpeciesD. melanogaster
NameRpn11Annotation symbolCG18174
Feature typeprotein_coding_geneFlyBase IDFBgn0028694
Gene Model StatusCurrent Stock availability 10 publicly available
Also Known Asp37B, DmS13
Genomic Location
Chromosome (arm)2LRecombination map
Cytogenetic map25C3-25C3Sequence location2L:5,058,404..5,059,816 [-]

Genomic Maps

GBrowse View Help
modENCODE GBrowse
detailed view
hide Summary Information
Automatically generated summary

See sections below for more information
The gene Rpn11 is referred to in FlyBase by the symbol Dmel\Rpn11 (CG18174, FBgn0028694). It is a protein_coding_gene from Drosophila melanogaster. There is experimental evidence that it has the molecular function: endopeptidase activity. There is experimental evidence that it is involved in the biological process: cellular process; proteolysis. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Mov34/MPN/PAD-1. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, larval/adult midgut, larval hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult ovary, adult testis, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult hindgut, adult spermathecae, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1628531_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Rpn11. Gene sequence location is 2L:5058404..5059816.

hide Recent Updates
Description
What does this section display?
This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
Update Feed
Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
References
FB2012_01
Sequence features
All updates Click here to see a list of all updates to this record from FB2010_08 and on.
hide Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map
Evidence for location
25C3-25C3  
Limits computationally determined from genome sequence between P{lacW}vkgk16721&P{lacW}Cg25Ck00405 and P{lacW}l(2)k11206k11206  
Experimentally Determined Cytological Location
Cytogenetic map
Notes
References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
hide Gene Model & Products
Please see the GBrowse view of Dmel\Rpn11 for information on other features
To submit a correction to a gene model please use the Contact FlyBase form
detailed view FBtr0079028 FBtr0079027 FBtr0079012 FBtr0100259 FBtr0100260 FBpp0078665 FBpp0078664 FBti0114856 FBti0067274 FBti0041890 FBti0109845 FBti0056360 FBti0018544 FBti0110032 FBti0102737
Comments on Gene Model
hide Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Associated CDS (aa)
FBtr0079027
  1234
  308
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
hide Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank protein
FBpp0078664  
34.4  
308  
6.05  
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
Mov34/MPN/PAD-1 (IPR000555)
hide Sequences Consistent with the Gene Model
DDBJ /
EMBL /
GenBank
DNA sequence
Protein sequence
Name
 
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL
hide Mapped Features
Mapped Features have been reorganized, please see this article for details.
Additional mapped features and mutations can be found on GBrowse or related reports.
Type
Symbol & Location
Additional Notes
References
hide External Data
Linkouts
Crossreferences
hide Expression Data
hideTranscript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hidePolypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
hide High-Throughput Expression Data
or
Untitled Document detailed view CG31918-RA Rpn11-RA
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

modENCODE Temporal Expression Data for FBgn0028694


   Styles
Linear
Logarithmic
Heatmap
   Scales
max expr for FBgn0028694
Very low expression bin max
Moderate expression bin max
High expression bin max
Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 hour embryonic stages, during late larval stages, during early pupal stages, in adult female stages.
[download data (TSV)]

Guide to modENCODE expression level colors
 
No expression (0 - 0)
 
Extremely low expression (1 - 10)
 
Very low expression (11 - 100)
 
Low expression (101 - 400)
 
Moderate expression (401 - 1400)
 
Moderately high expression (1401 - 4000)
 
High expression (4001 - 10000)
 
Very high expression (10001 - 100000)
 
Extremely high expression (100001 - 2000000)

Linear, scaled to maximum FBgn0028694 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 17370
embryo 02-04hr
 
 3959
embryo 04-06hr
 
 7435
embryo 06-08hr
 
 7724
embryo 08-10hr
 
 5823
embryo 10-12hr
 
 5759
embryo 12-14hr
 
 3503
embryo 14-16hr
 
 3732
embryo 16-18hr
 
 2741
embryo 18-20hr
 
 2623
embryo 20-22hr
 
 2123
embryo 22-24hr
 
 1980
larva L1
 
 4512
larva L2
 
 7640
larva L3 12hr old
 
 5465
larva L3 puffstage 1-2
 
 9214
larva L3 puffstage 3-6
 
 17051
larva L3 puffstage 7-9
 
 21920
white prepupae new
 
 24569
white prepupae 12hr
 
 11037
white prepupae 24hr
 
 10341
pupae 2d postWPP
 
 6648
pupae 3d postWPP
 
 4794
pupae 4d postWPP
 
 9497
adult male 01day
 
 6783
adult male 05day
 
 6053
adult male 30day
 
 6430
adult female 01day
 
 12102
adult female 05day
 
 13589
adult female 30day
 
 13533
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
Linear, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 (17370)
embryo 02-04hr
 (3959)
embryo 04-06hr
 (7435)
embryo 06-08hr
 (7724)
embryo 08-10hr
 (5823)
embryo 10-12hr
 (5759)
embryo 12-14hr
 (3503)
embryo 14-16hr
 (3732)
embryo 16-18hr
 (2741)
embryo 18-20hr
 (2623)
embryo 20-22hr
 (2123)
embryo 22-24hr
 (1980)
larva L1
 (4512)
larva L2
 (7640)
larva L3 12hr old
 (5465)
larva L3 puffstage 1-2
 (9214)
larva L3 puffstage 3-6
 (17051)
larva L3 puffstage 7-9
 (21920)
white prepupae new
 (24569)
white prepupae 12hr
 (11037)
white prepupae 24hr
 (10341)
pupae 2d postWPP
 (6648)
pupae 3d postWPP
 (4794)
pupae 4d postWPP
 (9497)
adult male 01day
 (6783)
adult male 05day
 (6053)
adult male 30day
 (6430)
adult female 01day
 (12102)
adult female 05day
 (13589)
adult female 30day
 (13533)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
Linear, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 (17370)
embryo 02-04hr
 (3959)
embryo 04-06hr
 (7435)
embryo 06-08hr
 (7724)
embryo 08-10hr
 (5823)
embryo 10-12hr
 (5759)
embryo 12-14hr
 (3503)
embryo 14-16hr
 (3732)
embryo 16-18hr
 (2741)
embryo 18-20hr
 (2623)
embryo 20-22hr
 (2123)
embryo 22-24hr
 (1980)
larva L1
 (4512)
larva L2
 (7640)
larva L3 12hr old
 (5465)
larva L3 puffstage 1-2
 (9214)
larva L3 puffstage 3-6
 (17051)
larva L3 puffstage 7-9
 (21920)
white prepupae new
 (24569)
white prepupae 12hr
 (11037)
white prepupae 24hr
 (10341)
pupae 2d postWPP
 (6648)
pupae 3d postWPP
 (4794)
pupae 4d postWPP
 (9497)
adult male 01day
 (6783)
adult male 05day
 (6053)
adult male 30day
 (6430)
adult female 01day
 (12102)
adult female 05day
 (13589)
adult female 30day
 (13533)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
Linear, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 (17370)
embryo 02-04hr
 
 3959
embryo 04-06hr
 
 7435
embryo 06-08hr
 
 7724
embryo 08-10hr
 
 5823
embryo 10-12hr
 
 5759
embryo 12-14hr
 
 3503
embryo 14-16hr
 
 3732
embryo 16-18hr
 
 2741
embryo 18-20hr
 
 2623
embryo 20-22hr
 
 2123
embryo 22-24hr
 
 1980
larva L1
 
 4512
larva L2
 
 7640
larva L3 12hr old
 
 5465
larva L3 puffstage 1-2
 
 9214
larva L3 puffstage 3-6
 (17051)
larva L3 puffstage 7-9
 (21920)
white prepupae new
 (24569)
white prepupae 12hr
 (11037)
white prepupae 24hr
 10341
pupae 2d postWPP
 
 6648
pupae 3d postWPP
 
 4794
pupae 4d postWPP
 
 9497
adult male 01day
 
 6783
adult male 05day
 
 6053
adult male 30day
 
 6430
adult female 01day
 (12102)
adult female 05day
 (13589)
adult female 30day
 (13533)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
Linear, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 17370
embryo 02-04hr
 
 3959
embryo 04-06hr
 
 7435
embryo 06-08hr
 
 7724
embryo 08-10hr
 
 5823
embryo 10-12hr
 
 5759
embryo 12-14hr
 
 3503
embryo 14-16hr
 
 3732
embryo 16-18hr
 
 2741
embryo 18-20hr
 
 2623
embryo 20-22hr
 
 2123
embryo 22-24hr
 
 1980
larva L1
 
 4512
larva L2
 
 7640
larva L3 12hr old
 
 5465
larva L3 puffstage 1-2
 
 9214
larva L3 puffstage 3-6
 
 17051
larva L3 puffstage 7-9
 
 21920
white prepupae new
 
 24569
white prepupae 12hr
 
 11037
white prepupae 24hr
 
 10341
pupae 2d postWPP
 
 6648
pupae 3d postWPP
 
 4794
pupae 4d postWPP
 
 9497
adult male 01day
 
 6783
adult male 05day
 
 6053
adult male 30day
 
 6430
adult female 01day
 
 12102
adult female 05day
 
 13589
adult female 30day
 
 13533
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
log, scaled to maximum FBgn0028694 expression level
Developmental Stage   Expression Level
embryo 00-02hr
 
 17370
embryo 02-04hr
 
 3959
embryo 04-06hr
 
 7435
embryo 06-08hr
 
 7724
embryo 08-10hr
 
 5823
embryo 10-12hr
 
 5759
embryo 12-14hr
 
 3503
embryo 14-16hr
 
 3732
embryo 16-18hr
 
 2741
embryo 18-20hr
 
 2623
embryo 20-22hr
 
 2123
embryo 22-24hr
 
 1980
larva L1
 
 4512
larva L2
 
 7640
larva L3 12hr old
 
 5465
larva L3 puffstage 1-2
 
 9214
larva L3 puffstage 3-6
 
 17051
larva L3 puffstage 7-9
 
 21920
white prepupae new
 
 24569
white prepupae 12hr
 
 11037
white prepupae 24hr
 
 10341
pupae 2d postWPP
 
 6648
pupae 3d postWPP
 
 4794
pupae 4d postWPP
 
 9497
adult male 01day
 
 6783
adult male 05day
 
 6053
adult male 30day
 
 6430
adult female 01day
 
 12102
adult female 05day
 
 13589
adult female 30day
 
 13533
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
log, scaled to Very low expression
Developmental Stage   Expression Level
embryo 00-02hr
 (17370)
embryo 02-04hr
 (3959)
embryo 04-06hr
 (7435)
embryo 06-08hr
 (7724)
embryo 08-10hr
 (5823)
embryo 10-12hr
 (5759)
embryo 12-14hr
 (3503)
embryo 14-16hr
 (3732)
embryo 16-18hr
 (2741)
embryo 18-20hr
 (2623)
embryo 20-22hr
 (2123)
embryo 22-24hr
 (1980)
larva L1
 (4512)
larva L2
 (7640)
larva L3 12hr old
 (5465)
larva L3 puffstage 1-2
 (9214)
larva L3 puffstage 3-6
 (17051)
larva L3 puffstage 7-9
 (21920)
white prepupae new
 (24569)
white prepupae 12hr
 (11037)
white prepupae 24hr
 (10341)
pupae 2d postWPP
 (6648)
pupae 3d postWPP
 (4794)
pupae 4d postWPP
 (9497)
adult male 01day
 (6783)
adult male 05day
 (6053)
adult male 30day
 (6430)
adult female 01day
 (12102)
adult female 05day
 (13589)
adult female 30day
 (13533)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
log, scaled to Moderate expression
Developmental Stage   Expression Level
embryo 00-02hr
 (17370)
embryo 02-04hr
 (3959)
embryo 04-06hr
 (7435)
embryo 06-08hr
 (7724)
embryo 08-10hr
 (5823)
embryo 10-12hr
 (5759)
embryo 12-14hr
 (3503)
embryo 14-16hr
 (3732)
embryo 16-18hr
 (2741)
embryo 18-20hr
 (2623)
embryo 20-22hr
 2123
embryo 22-24hr
 1980
larva L1
 (4512)
larva L2
 (7640)
larva L3 12hr old
 (5465)
larva L3 puffstage 1-2
 (9214)
larva L3 puffstage 3-6
 (17051)
larva L3 puffstage 7-9
 (21920)
white prepupae new
 (24569)
white prepupae 12hr
 (11037)
white prepupae 24hr
 (10341)
pupae 2d postWPP
 (6648)
pupae 3d postWPP
 (4794)
pupae 4d postWPP
 (9497)
adult male 01day
 (6783)
adult male 05day
 (6053)
adult male 30day
 (6430)
adult female 01day
 (12102)
adult female 05day
 (13589)
adult female 30day
 (13533)
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
log, scaled to High expression
Developmental Stage   Expression Level
embryo 00-02hr
 17370
embryo 02-04hr
 
 3959
embryo 04-06hr
 
 7435
embryo 06-08hr
 
 7724
embryo 08-10hr
 
 5823
embryo 10-12hr
 
 5759
embryo 12-14hr
 
 3503
embryo 14-16hr
 
 3732
embryo 16-18hr
 
 2741
embryo 18-20hr
 
 2623
embryo 20-22hr
 
 2123
embryo 22-24hr
 
 1980
larva L1
 
 4512
larva L2
 
 7640
larva L3 12hr old
 
 5465
larva L3 puffstage 1-2
 
 9214
larva L3 puffstage 3-6
 17051
larva L3 puffstage 7-9
 (21920)
white prepupae new
 (24569)
white prepupae 12hr
 11037
white prepupae 24hr
 10341
pupae 2d postWPP
 
 6648
pupae 3d postWPP
 
 4794
pupae 4d postWPP
 
 9497
adult male 01day
 
 6783
adult male 05day
 
 6053
adult male 30day
 
 6430
adult female 01day
 12102
adult female 05day
 13589
adult female 30day
 13533
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
log, scaled to Extremely high expression
Developmental Stage   Expression Level
embryo 00-02hr
 
 17370
embryo 02-04hr
 
 3959
embryo 04-06hr
 
 7435
embryo 06-08hr
 
 7724
embryo 08-10hr
 
 5823
embryo 10-12hr
 
 5759
embryo 12-14hr
 
 3503
embryo 14-16hr
 
 3732
embryo 16-18hr
 
 2741
embryo 18-20hr
 
 2623
embryo 20-22hr
 
 2123
embryo 22-24hr
 
 1980
larva L1
 
 4512
larva L2
 
 7640
larva L3 12hr old
 
 5465
larva L3 puffstage 1-2
 
 9214
larva L3 puffstage 3-6
 
 17051
larva L3 puffstage 7-9
 
 21920
white prepupae new
 
 24569
white prepupae 12hr
 
 11037
white prepupae 24hr
 
 10341
pupae 2d postWPP
 
 6648
pupae 3d postWPP
 
 4794
pupae 4d postWPP
 
 9497
adult male 01day
 
 6783
adult male 05day
 
 6053
adult male 30day
 
 6430
adult female 01day
 
 12102
adult female 05day
 
 13589
adult female 30day
 
 13533
Expression Level Scale
 None 
 Extremely low 
 Very low 
 Low 
 Moderate 
 Moderately high 
 High 
 Very high 
 Extremely high 
Heatmap
Developmental Stage   Expression Level
embryo 00-02hr
 
 
embryo 02-04hr
 
 
embryo 04-06hr
 
 
embryo 06-08hr
 
 
embryo 08-10hr
 
 
embryo 10-12hr
 
 
embryo 12-14hr
 
 
embryo 14-16hr
 
 
embryo 16-18hr
 
 
embryo 18-20hr
 
 
embryo 20-22hr
 
 
embryo 22-24hr
 
 
larva L1
 
 
larva L2
 
 
larva L3 12hr old
 
 
larva L3 puffstage 1-2
 
 
larva L3 puffstage 3-6
 
 
larva L3 puffstage 7-9
 
 
white prepupae new
 
 
white prepupae 12hr
 
 
white prepupae 24hr
 
 
pupae 2d postWPP
 
 
pupae 3d postWPP
 
 
pupae 4d postWPP
 
 
adult male 01day
 
 
adult male 05day
 
 
adult male 30day
 
 
adult female 01day
 
 
adult female 05day
 
 
adult female 30day
 
 

FlyAtlas Anatomical Expression Data for FBgn0028694


   Styles
Linear
Logarithmic
Heatmap
Back-to-back
   Scales
max expr for FBgn0028694
Moderate expression bin max
High level expression bin max
Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, larval/adult midgut, larval hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult ovary, adult testis, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult hindgut, adult spermathecae, adult male accessory gland.
[download data (TSV)]

Guide to FlyAtlas expression level colors
 
No expression (0 - 9.999)
 
Low expression (10 - 99.999)
 
Moderate expression (100 - 499.999)
 
High level expression (500 - 999.999)
 
Very high expression (1000 - 25000)

Linear, scaled to maximum FBgn0028694 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 833.4
Larval Midgut
 
 1077.7
Larval Hindgut
 
 995.8
Larval Malpighian Tubules
 
 1686.7
Larval Fat Body
 
 734.8
Larval Salivary Gland
 
 1016.7
Larval Trachea
 
 854.1
Larval Carcass
 
 1775.35
Adult Head
 
 401.6
Adult Eye
 
 263.725
Adult Brain
 
 276.8
Adult Thoracic-Abdominal Ganglion
 
 280.4
Adult Crop
 
 521.7
Adult Midgut
 
 672.9
Adult Hindgut
 
 489.1
Adult Malpighian Tubules
 
 642.1
Adult Fat Body
 
 1102.2
Adult Salivary Gland
 
 520.8
Adult Heart
 
 1104.95
Adult VirginFemale Spermatheca
 
 453.1
Adult InseminatedFemale Spermatheca
 
 430.2
Adult Ovary
 
 1163.9
Adult Testis
 
 550.1
Adult Male Accessory Gland
 
 455.8
Adult Carcass
 
 743.5
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Linear, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 (833.4)
Larval Midgut
 (1077.7)
Larval Hindgut
 (995.8)
Larval Malpighian Tubules
 (1686.7)
Larval Fat Body
 (734.8)
Larval Salivary Gland
 (1016.7)
Larval Trachea
 (854.1)
Larval Carcass
 (1775.35)
Adult Head
 
 401.6
Adult Eye
 
 263.725
Adult Brain
 
 276.8
Adult Thoracic-Abdominal Ganglion
 
 280.4
Adult Crop
 521.7
Adult Midgut
 (672.9)
Adult Hindgut
 
 489.1
Adult Malpighian Tubules
 (642.1)
Adult Fat Body
 (1102.2)
Adult Salivary Gland
 520.8
Adult Heart
 (1104.95)
Adult VirginFemale Spermatheca
 
 453.1
Adult InseminatedFemale Spermatheca
 
 430.2
Adult Ovary
 (1163.9)
Adult Testis
 (550.1)
Adult Male Accessory Gland
 
 455.8
Adult Carcass
 (743.5)
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
Linear, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 
 833.4
Larval Midgut
 1077.7
Larval Hindgut
 
 995.8
Larval Malpighian Tubules
 (1686.7)
Larval Fat Body
 
 734.8
Larval Salivary Gland
 1016.7
Larval Trachea
 
 854.1
Larval Carcass
 (1775.35)
Adult Head
 
 401.6
Adult Eye
 
 263.725
Adult Brain
 
 276.8
Adult Thoracic-Abdominal Ganglion
 
 280.4
Adult Crop
 
 521.7
Adult Midgut
 
 672.9
Adult Hindgut
 
 489.1
Adult Malpighian Tubules
 
 642.1
Adult Fat Body
 (1102.2)
Adult Salivary Gland
 
 520.8
Adult Heart
 (1104.95)
Adult VirginFemale Spermatheca
 
 453.1
Adult InseminatedFemale Spermatheca
 
 430.2
Adult Ovary
 (1163.9)
Adult Testis
 
 550.1
Adult Male Accessory Gland
 
 455.8
Adult Carcass
 
 743.5
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Linear, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 833.4
Larval Midgut
 
 1077.7
Larval Hindgut
 
 995.8
Larval Malpighian Tubules
 
 1686.7
Larval Fat Body
 
 734.8
Larval Salivary Gland
 
 1016.7
Larval Trachea
 
 854.1
Larval Carcass
 
 1775.35
Adult Head
 
 401.6
Adult Eye
 
 263.725
Adult Brain
 
 276.8
Adult Thoracic-Abdominal Ganglion
 
 280.4
Adult Crop
 
 521.7
Adult Midgut
 
 672.9
Adult Hindgut
 
 489.1
Adult Malpighian Tubules
 
 642.1
Adult Fat Body
 
 1102.2
Adult Salivary Gland
 
 520.8
Adult Heart
 
 1104.95
Adult VirginFemale Spermatheca
 
 453.1
Adult InseminatedFemale Spermatheca
 
 430.2
Adult Ovary
 
 1163.9
Adult Testis
 
 550.1
Adult Male Accessory Gland
 
 455.8
Adult Carcass
 
 743.5
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to maximum FBgn0028694 expression level
Tissue   Expression Level
Larval Central Nervous System
 
 833.4
Larval Midgut
 
 1077.7
Larval Hindgut
 
 995.8
Larval Malpighian Tubules
 
 1686.7
Larval Fat Body
 
 734.8
Larval Salivary Gland
 
 1016.7
Larval Trachea
 
 854.1
Larval Carcass
 
 1775.35
Adult Head
 
 401.6
Adult Eye
 
 263.725
Adult Brain
 
 276.8
Adult Thoracic-Abdominal Ganglion
 
 280.4
Adult Crop
 
 521.7
Adult Midgut
 
 672.9
Adult Hindgut
 
 489.1
Adult Malpighian Tubules
 
 642.1
Adult Fat Body
 
 1102.2
Adult Salivary Gland
 
 520.8
Adult Heart
 
 1104.95
Adult VirginFemale Spermatheca
 
 453.1
Adult InseminatedFemale Spermatheca
 
 430.2
Adult Ovary
 
 1163.9
Adult Testis
 
 550.1
Adult Male Accessory Gland
 
 455.8
Adult Carcass
 
 743.5
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Moderate expression
Tissue   Expression Level
Larval Central Nervous System
 (833.4)
Larval Midgut
 (1077.7)
Larval Hindgut
 (995.8)
Larval Malpighian Tubules
 (1686.7)
Larval Fat Body
 734.8
Larval Salivary Gland
 (1016.7)
Larval Trachea
 (854.1)
Larval Carcass
 (1775.35)
Adult Head
 
 401.6
Adult Eye
 
 263.725
Adult Brain
 
 276.8
Adult Thoracic-Abdominal Ganglion
 
 280.4
Adult Crop
 521.7
Adult Midgut
 672.9
Adult Hindgut
 
 489.1
Adult Malpighian Tubules
 642.1
Adult Fat Body
 (1102.2)
Adult Salivary Gland
 520.8
Adult Heart
 (1104.95)
Adult VirginFemale Spermatheca
 
 453.1
Adult InseminatedFemale Spermatheca
 
 430.2
Adult Ovary
 (1163.9)
Adult Testis
 550.1
Adult Male Accessory Gland
 
 455.8
Adult Carcass
 743.5
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
log, scaled to High level expression
Tissue   Expression Level
Larval Central Nervous System
 
 833.4
Larval Midgut
 1077.7
Larval Hindgut
 
 995.8
Larval Malpighian Tubules
 1686.7
Larval Fat Body
 
 734.8
Larval Salivary Gland
 1016.7
Larval Trachea
 
 854.1
Larval Carcass
 (1775.35)
Adult Head
 
 401.6
Adult Eye
 
 263.725
Adult Brain
 
 276.8
Adult Thoracic-Abdominal Ganglion
 
 280.4
Adult Crop
 
 521.7
Adult Midgut
 
 672.9
Adult Hindgut
 
 489.1
Adult Malpighian Tubules
 
 642.1
Adult Fat Body
 1102.2
Adult Salivary Gland
 
 520.8
Adult Heart
 1104.95
Adult VirginFemale Spermatheca
 
 453.1
Adult InseminatedFemale Spermatheca
 
 430.2
Adult Ovary
 1163.9
Adult Testis
 
 550.1
Adult Male Accessory Gland
 
 455.8
Adult Carcass
 
 743.5
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
log, scaled to Very high expression
Tissue   Expression Level
Larval Central Nervous System
 
 833.4
Larval Midgut
 
 1077.7
Larval Hindgut
 
 995.8
Larval Malpighian Tubules
 
 1686.7
Larval Fat Body
 
 734.8
Larval Salivary Gland
 
 1016.7
Larval Trachea
 
 854.1
Larval Carcass
 
 1775.35
Adult Head
 
 401.6
Adult Eye
 
 263.725
Adult Brain
 
 276.8
Adult Thoracic-Abdominal Ganglion
 
 280.4
Adult Crop
 
 521.7
Adult Midgut
 
 672.9
Adult Hindgut
 
 489.1
Adult Malpighian Tubules
 
 642.1
Adult Fat Body
 
 1102.2
Adult Salivary Gland
 
 520.8
Adult Heart
 
 1104.95
Adult VirginFemale Spermatheca
 
 453.1
Adult InseminatedFemale Spermatheca
 
 430.2
Adult Ovary
 
 1163.9
Adult Testis
 
 550.1
Adult Male Accessory Gland
 
 455.8
Adult Carcass
 
 743.5
Expression Level Scale
 None 
 Low 
 Moderate 
 High 
 Very high 
Heatmap
Tissue   Expression Level
Larval Central Nervous System
 
 
Larval Midgut
 
 
Larval Hindgut
 
 
Larval Malpighian Tubules
 
 
Larval Fat Body
 
 
Larval Salivary Gland
 
 
Larval Trachea
 
 
Larval Carcass
 
 
Adult Head
 
 
Adult Eye
 
 
Adult Brain
 
 
Adult Thoracic-Abdominal Ganglion
 
 
Adult Crop
 
 
Adult Midgut
 
 
Adult Hindgut
 
 
Adult Malpighian Tubules
 
 
Adult Fat Body
 
 
Adult Salivary Gland
 
 
Adult Heart
 
 
Adult VirginFemale Spermatheca
 
 
Adult InseminatedFemale Spermatheca
 
 
Adult Ovary
 
 
Adult Testis
 
 
Adult Male Accessory Gland
 
 
Adult Carcass
 
 

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level Tissue Adult Expression Level
 
NA 
Head
 
 401.6
 
NA 
Eye
 
 263.725
 
NA 
Brain
 
 276.8
 
833.4 
Central Nervous System
 
 NA
 
NA 
Thoracic-Abdominal Ganglion
 
 280.4
 
NA 
Crop
 
 521.7
 
1077.7 
Midgut
 
 672.9
 
995.8 
Hindgut
 
 489.1
 
1686.7 
Malpighian Tubules
 
 642.1
 
734.8 
Fat Body
 
 1102.2
 
1016.7 
Salivary Gland
 
 520.8
 
NA 
Heart
 
 1104.95
 
854.1 
Trachea
 
 NA
 
NA 
VirginFemale Spermatheca
 
 453.1
 
NA 
InseminatedFemale Spermatheca
 
 430.2
 
NA 
Ovary
 
 1163.9
 
NA 
Testis
 
 550.1
 
NA 
Male Accessory Gland
 
 455.8
 
1775.35 
Carcass
 
 743.5

modENCODE Temporal Expression Data (Graveley et al., 2011)
FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
hide Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
hide External Data & Images
Linkouts
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyExpress - Embryonic expression images (BDGP data)
hide Alleles & Phenotypes
hide Summary of Allele Phenotypes
Lethality
Allele
Phenotype manifest in
Allele
hide Classical Alleles ( 4 )
For All Classical Alleles Show

Allele of Rpn11ClassMutagenStocksKnown lesion
Rpn11f003863 --
Rpn11BG016942 --
Rpn11d07228
1 --
Rpn11f003961 --
hide Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show

Allele of Rpn11ClassMutagenStocksKnown lesion
Rpn11GD88882 Yes
Rpn11HMS000711 Yes
hide Aneuploid Aberrations
hide Transgenic Constructs & Insertions
Transgenic Constructs
Type of construct
Name
Expression data
UAS construct
Insertions
Type of insertions
Name
Expression data
insertion of mobile activating element
hide Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )
hide Terms Based on Experimental Evidence ( 5 terms )
Molecular Function
CV term
References
inferred from direct assay
Biological Process
CV term
References
inferred from mutant phenotype
inferred from direct assay AND inferred from sequence or structural similarity with Saccharomyces RPN11
inferred from mutant phenotype
Cellular Component
CV term
References
inferred from direct assay AND inferred from sequence or structural similarity with NCBI:NP_005796
hide Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term
References
inferred from sequence or structural similarity with Saccharomyces RPN11
non-traceable author statement
hide Sequence Ontology: Class of Gene
hide Interactions & Pathways
hide Summary of Physical Interactions
Protein-protein
Interacting group
Assay
References
hide Summary of Genetic Interactions
Interacts with
Please look at the allele data for full details of the genetic interactions
Rpn11 allele
Gene
References
hide External Data
Linkouts
BioGRID - A database of protein and genetic interactions
DPiM - DPiM, Drosophila Protein interaction Map
DroID - A comprehensive database of gene and protein interactions.
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
hide Orthologs
Genome-wide drosophilid orthologs
Curated drosophilid orthologs
Linkouts
InParanoid A subset of ortholog calls from InParanoid.
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
hide Stocks & Reagents
hide Stocks Listed in FlyBase ( 10 )
Bloomington
Harvard
Kyoto
VDRC
hide Genomic Clones ( 1 )
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
hide cDNA Clones ( 46 )
Please Note
This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
hide RNAi & Array Information
Linkouts
DRSC - Results from RNAi screens.
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
hide Antibody Information
hide Other Information
hide Discoverer
hide Etymology
hide Identification
hide Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
hide Other Comments
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
hide External Crossreferences & Linkouts
Sequence Crossreferences
RefSeq (Transcripts)
RefSeq (Proteins)
Entrez Gene - A searchable database of RefSeq genes.
Other Crossreferences
InterPro domains - A database of protein families, domains, and functional sites
Mov34/MPN/PAD-1 (IPR000555)
Linkouts
BioGRID - A database of protein and genetic interactions
DPiM - DPiM, Drosophila Protein interaction Map
DroID - A comprehensive database of gene and protein interactions.
DRSC - Results from RNAi screens.
FLIGHT - Cell culture data for RNAi and other high-throughput technologies
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans
FlyReactome - A curated knowledgebase of Drosophila melanogaster pathways
GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
InParanoid A subset of ortholog calls from InParanoid.
InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.
modMine - Data generated by the modENCODE project.
OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs.
hide Synonyms & Secondary IDs ( 10 )
Reported As
Symbol Synonym
S13
 
Name Synonym
Rpn11
 
yippee interacting protein 5
Secondary FlyBase IDs
hide References ( 37 )
Generate a list of
List References by type
hide Recent research papers ( 3 )
Booker et al., 2011, BMC Genomics 12: 50
False negative rates in Drosophila cell-based RNAi screens: a case study. [FBrf0212969]
Blanco et al., 2010, BMC Dev. Biol. 10: 94
Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812]
Monzo et al., 2010, Dev. Biol. 340(2): 408--418
Proteomic analysis reveals CCT is a target of Fragile X mental retardation protein regulation in Drosophila. [FBrf0210519]