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Gene Dmel\CG8997

General Information
Symbol	Dmel\CG8997	Species	D. melanogaster
Name		Annotation symbol	CG8997
Feature type	protein_coding_gene	FlyBase ID	FBgn0028920
Gene Model Status	Current	Stock availability	3 publicly available
Also Known As	BG:DS00941.12
Genomic Location
Chromosome (arm)	2L	Recombination map
Cytogenetic map	34D7-34D7	Sequence location	2L:13,844,377..13,845,309 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG8997 (FBgn0028920). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Haemolymph juvenile hormone binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of extremely low expression. Peak expression observed during late larval stages. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut. Comments on Affy2 ProbeSet: ProbeSet 1629520_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG8997. Gene sequence location is 2L:13844377..13845309.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 34D7-34D7   Limits computationally determined from genome sequence between P{lacW}Sosk05224&P{lacW}RpII33k05605 and P{lacW}l(2)34Fak00811&P{PZ}wb09437
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG8997 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG8997-RA FBtr0080563  NM_135837   869   260
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG8997-PA   FBpp0080140   28.1   260   4.15     NP_609681   AAF53345
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Haemolymph juvenile hormone binding (IPR010562)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014134 AAF53345   AE003408 AAF44828   AI293855   AI294389   AI297405   AI297539   BT031047   BT088958   BT100275   CK657269   CK660369   CK661837   CK661901   CK662182   CO180301   CO181116   CO181613   CO183105   CO191144   CO191555   CO192791   CO193436   CO193914   CO194897   CO195283   CO275084   EC198224   EL877371   EV575744   EV582707   EV585793   EV587146   EV588732   EV590891   EV592897   EV599657   L39629
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9V3A0
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1.5 Larval Midgut    5871.2 Larval Hindgut    87.8 Larval Malpighian Tubules    1.7 Larval Fat Body    87 Larval Salivary Gland    2.3 Larval Trachea    57.525 Larval Carcass    0.925 Adult Head    3.7 Adult Eye    5.225 Adult Brain    0.5 Adult Thoracic-Abdominal Ganglion    0.7 Adult Crop    2.8 Adult Midgut    6019.5 Adult Hindgut    4.1 Adult Malpighian Tubules    1.5 Adult Fat Body    2.3 Adult Salivary Gland    4.4 Adult Heart    3.3 Adult VirginFemale Spermatheca    3.9 Adult InseminatedFemale Spermatheca    1 Adult Ovary    1.1 Adult Testis    0.8 Adult Male Accessory Gland    3.4 Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    1.5 Larval Midgut  (5871.2) Larval Hindgut    87.8 Larval Malpighian Tubules    1.7 Larval Fat Body    87 Larval Salivary Gland    2.3 Larval Trachea    57.525 Larval Carcass    0.925 Adult Head    3.7 Adult Eye    5.225 Adult Brain    0.5 Adult Thoracic-Abdominal Ganglion    0.7 Adult Crop    2.8 Adult Midgut  (6019.5) Adult Hindgut    4.1 Adult Malpighian Tubules    1.5 Adult Fat Body    2.3 Adult Salivary Gland    4.4 Adult Heart    3.3 Adult VirginFemale Spermatheca    3.9 Adult InseminatedFemale Spermatheca    1 Adult Ovary    1.1 Adult Testis    0.8 Adult Male Accessory Gland    3.4 Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    1.5 Larval Midgut  (5871.2) Larval Hindgut    87.8 Larval Malpighian Tubules    1.7 Larval Fat Body    87 Larval Salivary Gland    2.3 Larval Trachea    57.525 Larval Carcass    0.925 Adult Head    3.7 Adult Eye    5.225 Adult Brain    0.5 Adult Thoracic-Abdominal Ganglion    0.7 Adult Crop    2.8 Adult Midgut  (6019.5) Adult Hindgut    4.1 Adult Malpighian Tubules    1.5 Adult Fat Body    2.3 Adult Salivary Gland    4.4 Adult Heart    3.3 Adult VirginFemale Spermatheca    3.9 Adult InseminatedFemale Spermatheca    1 Adult Ovary    1.1 Adult Testis    0.8 Adult Male Accessory Gland    3.4 Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1.5 Larval Midgut    5871.2 Larval Hindgut    87.8 Larval Malpighian Tubules    1.7 Larval Fat Body    87 Larval Salivary Gland    2.3 Larval Trachea    57.525 Larval Carcass    0.925 Adult Head    3.7 Adult Eye    5.225 Adult Brain    0.5 Adult Thoracic-Abdominal Ganglion    0.7 Adult Crop    2.8 Adult Midgut    6019.5 Adult Hindgut    4.1 Adult Malpighian Tubules    1.5 Adult Fat Body    2.3 Adult Salivary Gland    4.4 Adult Heart    3.3 Adult VirginFemale Spermatheca    3.9 Adult InseminatedFemale Spermatheca    1 Adult Ovary    1.1 Adult Testis    0.8 Adult Male Accessory Gland    3.4 Adult Carcass    3.4 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1.5 Larval Midgut    5871.2 Larval Hindgut    87.8 Larval Malpighian Tubules    1.7 Larval Fat Body    87 Larval Salivary Gland    2.3 Larval Trachea    57.525 Larval Carcass    0.925 Adult Head    3.7 Adult Eye    5.225 Adult Brain    0.5 Adult Thoracic-Abdominal Ganglion    0.7 Adult Crop    2.8 Adult Midgut    6019.5 Adult Hindgut    4.1 Adult Malpighian Tubules    1.5 Adult Fat Body    2.3 Adult Salivary Gland    4.4 Adult Heart    3.3 Adult VirginFemale Spermatheca    3.9 Adult InseminatedFemale Spermatheca    1 Adult Ovary    1.1 Adult Testis    0.8 Adult Male Accessory Gland    3.4 Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    1.5 Larval Midgut  (5871.2) Larval Hindgut    87.8 Larval Malpighian Tubules    1.7 Larval Fat Body    87 Larval Salivary Gland    2.3 Larval Trachea    57.525 Larval Carcass    0.925 Adult Head    3.7 Adult Eye    5.225 Adult Brain    0.5 Adult Thoracic-Abdominal Ganglion    0.7 Adult Crop    2.8 Adult Midgut  (6019.5) Adult Hindgut    4.1 Adult Malpighian Tubules    1.5 Adult Fat Body    2.3 Adult Salivary Gland    4.4 Adult Heart    3.3 Adult VirginFemale Spermatheca    3.9 Adult InseminatedFemale Spermatheca    1 Adult Ovary    1.1 Adult Testis    0.8 Adult Male Accessory Gland    3.4 Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    1.5 Larval Midgut  (5871.2) Larval Hindgut    87.8 Larval Malpighian Tubules    1.7 Larval Fat Body    87 Larval Salivary Gland    2.3 Larval Trachea    57.525 Larval Carcass    0.925 Adult Head    3.7 Adult Eye    5.225 Adult Brain    0.5 Adult Thoracic-Abdominal Ganglion    0.7 Adult Crop    2.8 Adult Midgut  (6019.5) Adult Hindgut    4.1 Adult Malpighian Tubules    1.5 Adult Fat Body    2.3 Adult Salivary Gland    4.4 Adult Heart    3.3 Adult VirginFemale Spermatheca    3.9 Adult InseminatedFemale Spermatheca    1 Adult Ovary    1.1 Adult Testis    0.8 Adult Male Accessory Gland    3.4 Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1.5 Larval Midgut    5871.2 Larval Hindgut    87.8 Larval Malpighian Tubules    1.7 Larval Fat Body    87 Larval Salivary Gland    2.3 Larval Trachea    57.525 Larval Carcass    0.925 Adult Head    3.7 Adult Eye    5.225 Adult Brain    0.5 Adult Thoracic-Abdominal Ganglion    0.7 Adult Crop    2.8 Adult Midgut    6019.5 Adult Hindgut    4.1 Adult Malpighian Tubules    1.5 Adult Fat Body    2.3 Adult Salivary Gland    4.4 Adult Heart    3.3 Adult VirginFemale Spermatheca    3.9 Adult InseminatedFemale Spermatheca    1 Adult Ovary    1.1 Adult Testis    0.8 Adult Male Accessory Gland    3.4 Adult Carcass    3.4 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    3.7   NA  Eye    5.225   NA  Brain    0.5   1.5  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    0.7   NA  Crop    2.8   5871.2  Midgut    6019.5   87.8  Hindgut    4.1   1.7  Malpighian Tubules    1.5   87  Fat Body    2.3   2.3  Salivary Gland    4.4   NA  Heart    3.3   no informative data  Trachea    NA   NA  VirginFemale Spermatheca    3.9   NA  InseminatedFemale Spermatheca    1   NA  Ovary    1.1   NA  Testis    0.8   NA  Male Accessory Gland    3.4   0.925  Carcass    3.4 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    129 central nervous system, larvae L3    3 central nervous system, pupae P8    0 head, virgin 1-day female    1 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    2 head, mated 4-day female    0 head, mated 20-day female    1 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    48 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    3228 digestive system, 1-day adult    1374 digestive system, 4-day adult    759 digestive system, 20-day adult    1030 fat body, larvae L3 wandering    5 fat body, white prepupae    20 fat body, pupae P8    0 carcass, larvae L3 wandering    12 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    76 accessory gland, mated 4-day male    96 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (129) central nervous system, larvae L3    3 central nervous system, pupae P8    0 head, virgin 1-day female    1 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    2 head, mated 4-day female    0 head, mated 20-day female    1 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering  (48) salivary gland, white prepupae    6 digestive system, larvae L3 wandering  (3228) digestive system, 1-day adult  (1374) digestive system, 4-day adult  (759) digestive system, 20-day adult  (1030) fat body, larvae L3 wandering    5 fat body, white prepupae    20 fat body, pupae P8    0 carcass, larvae L3 wandering    12 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male  (76) accessory gland, mated 4-day male  (96) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (129) central nervous system, larvae L3    3 central nervous system, pupae P8    0 head, virgin 1-day female    1 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    2 head, mated 4-day female    0 head, mated 20-day female    1 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    48 salivary gland, white prepupae    6 digestive system, larvae L3 wandering  (3228) digestive system, 1-day adult  (1374) digestive system, 4-day adult  (759) digestive system, 20-day adult  (1030) fat body, larvae L3 wandering    5 fat body, white prepupae    20 fat body, pupae P8    0 carcass, larvae L3 wandering    12 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    76 accessory gland, mated 4-day male    96 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    129 central nervous system, larvae L3    3 central nervous system, pupae P8    0 head, virgin 1-day female    1 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    2 head, mated 4-day female    0 head, mated 20-day female    1 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    48 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    3228 digestive system, 1-day adult    1374 digestive system, 4-day adult    759 digestive system, 20-day adult    1030 fat body, larvae L3 wandering    5 fat body, white prepupae    20 fat body, pupae P8    0 carcass, larvae L3 wandering    12 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    76 accessory gland, mated 4-day male    96 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    129 central nervous system, larvae L3    3 central nervous system, pupae P8    0 head, virgin 1-day female    1 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    2 head, mated 4-day female    0 head, mated 20-day female    1 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    48 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    3228 digestive system, 1-day adult    1374 digestive system, 4-day adult    759 digestive system, 20-day adult    1030 fat body, larvae L3 wandering    5 fat body, white prepupae    20 fat body, pupae P8    0 carcass, larvae L3 wandering    12 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    76 accessory gland, mated 4-day male    96 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (129) central nervous system, larvae L3    3 central nervous system, pupae P8    0 head, virgin 1-day female    1 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    2 head, mated 4-day female    0 head, mated 20-day female    1 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering  (48) salivary gland, white prepupae    6 digestive system, larvae L3 wandering  (3228) digestive system, 1-day adult  (1374) digestive system, 4-day adult  (759) digestive system, 20-day adult  (1030) fat body, larvae L3 wandering    5 fat body, white prepupae    20 fat body, pupae P8    0 carcass, larvae L3 wandering    12 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male  (76) accessory gland, mated 4-day male  (96) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  129 central nervous system, larvae L3    3 central nervous system, pupae P8    0 head, virgin 1-day female    1 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    2 head, mated 4-day female    0 head, mated 20-day female    1 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    48 salivary gland, white prepupae    6 digestive system, larvae L3 wandering  (3228) digestive system, 1-day adult  (1374) digestive system, 4-day adult  (759) digestive system, 20-day adult  (1030) fat body, larvae L3 wandering    5 fat body, white prepupae    20 fat body, pupae P8    0 carcass, larvae L3 wandering    12 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    76 accessory gland, mated 4-day male    96 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    129 central nervous system, larvae L3    3 central nervous system, pupae P8    0 head, virgin 1-day female    1 head, virgin 4-day female    0 head, virgin 20-day female    0 head, mated 1-day female    2 head, mated 4-day female    0 head, mated 20-day female    1 head, mated 1-day male    0 head, mated 4-day male    0 head, mated 20-day male    0 salivary gland, larvae L3 wandering    48 salivary gland, white prepupae    6 digestive system, larvae L3 wandering    3228 digestive system, 1-day adult    1374 digestive system, 4-day adult    759 digestive system, 20-day adult    1030 fat body, larvae L3 wandering    5 fat body, white prepupae    20 fat body, pupae P8    0 carcass, larvae L3 wandering    12 carcass, 1-day adult    5 carcass, 4-day adult    8 carcass, 20-day adult    8 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    76 accessory gland, mated 4-day male    96 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of extremely high expression to a trough of extremely low expression. Peak expression observed during late larval stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    2 embryo 18-20hr    11 embryo 20-22hr    41 embryo 22-24hr    40 larva L1    351 larva L2    376 larva L3 12hr old    434 larva L3 puffstage 1-2    1419 larva L3 puffstage 3-6    1085 larva L3 puffstage 7-9    1251 white prepupae new    910 white prepupae 12hr    5 white prepupae 24hr    3 pupae 2d postWPP    1 pupae 3d postWPP    0 pupae 4d postWPP    3 adult male 01day    439 adult male 05day    672 adult male 30day    485 adult female 01day    561 adult female 05day    428 adult female 30day    215 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    2 embryo 18-20hr    11 embryo 20-22hr  (41) embryo 22-24hr  (40) larva L1  (351) larva L2  (376) larva L3 12hr old  (434) larva L3 puffstage 1-2  (1419) larva L3 puffstage 3-6  (1085) larva L3 puffstage 7-9  (1251) white prepupae new  (910) white prepupae 12hr    5 white prepupae 24hr    3 pupae 2d postWPP    1 pupae 3d postWPP    0 pupae 4d postWPP    3 adult male 01day  (439) adult male 05day  (672) adult male 30day  (485) adult female 01day  (561) adult female 05day  (428) adult female 30day  (215) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    2 embryo 18-20hr    11 embryo 20-22hr    41 embryo 22-24hr    40 larva L1  (351) larva L2  (376) larva L3 12hr old  (434) larva L3 puffstage 1-2  (1419) larva L3 puffstage 3-6  (1085) larva L3 puffstage 7-9  (1251) white prepupae new  (910) white prepupae 12hr    5 white prepupae 24hr    3 pupae 2d postWPP    1 pupae 3d postWPP    0 pupae 4d postWPP    3 adult male 01day  (439) adult male 05day  (672) adult male 30day  (485) adult female 01day  (561) adult female 05day  (428) adult female 30day  (215) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    2 embryo 18-20hr    11 embryo 20-22hr    41 embryo 22-24hr    40 larva L1    351 larva L2    376 larva L3 12hr old    434 larva L3 puffstage 1-2    1419 larva L3 puffstage 3-6    1085 larva L3 puffstage 7-9    1251 white prepupae new    910 white prepupae 12hr    5 white prepupae 24hr    3 pupae 2d postWPP    1 pupae 3d postWPP    0 pupae 4d postWPP    3 adult male 01day    439 adult male 05day    672 adult male 30day    485 adult female 01day    561 adult female 05day    428 adult female 30day    215 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    2 embryo 18-20hr    11 embryo 20-22hr    41 embryo 22-24hr    40 larva L1    351 larva L2    376 larva L3 12hr old    434 larva L3 puffstage 1-2    1419 larva L3 puffstage 3-6    1085 larva L3 puffstage 7-9    1251 white prepupae new    910 white prepupae 12hr    5 white prepupae 24hr    3 pupae 2d postWPP    1 pupae 3d postWPP    0 pupae 4d postWPP    3 adult male 01day    439 adult male 05day    672 adult male 30day    485 adult female 01day    561 adult female 05day    428 adult female 30day    215 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    2 embryo 18-20hr    11 embryo 20-22hr  (41) embryo 22-24hr  (40) larva L1  (351) larva L2  (376) larva L3 12hr old  (434) larva L3 puffstage 1-2  (1419) larva L3 puffstage 3-6  (1085) larva L3 puffstage 7-9  (1251) white prepupae new  (910) white prepupae 12hr    5 white prepupae 24hr    3 pupae 2d postWPP    1 pupae 3d postWPP    0 pupae 4d postWPP    3 adult male 01day  (439) adult male 05day  (672) adult male 30day  (485) adult female 01day  (561) adult female 05day  (428) adult female 30day  (215) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    2 embryo 18-20hr    11 embryo 20-22hr    41 embryo 22-24hr    40 larva L1  (351) larva L2  (376) larva L3 12hr old  (434) larva L3 puffstage 1-2  (1419) larva L3 puffstage 3-6  (1085) larva L3 puffstage 7-9  (1251) white prepupae new  (910) white prepupae 12hr    5 white prepupae 24hr    3 pupae 2d postWPP    1 pupae 3d postWPP    0 pupae 4d postWPP    3 adult male 01day  (439) adult male 05day  (672) adult male 30day  (485) adult female 01day  (561) adult female 05day  (428) adult female 30day  (215) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    1 embryo 08-10hr    1 embryo 10-12hr    0 embryo 12-14hr    0 embryo 14-16hr    1 embryo 16-18hr    2 embryo 18-20hr    11 embryo 20-22hr    41 embryo 22-24hr    40 larva L1    351 larva L2    376 larva L3 12hr old    434 larva L3 puffstage 1-2    1419 larva L3 puffstage 3-6    1085 larva L3 puffstage 7-9    1251 white prepupae new    910 white prepupae 12hr    5 white prepupae 24hr    3 pupae 2d postWPP    1 pupae 3d postWPP    0 pupae 4d postWPP    3 adult male 01day    439 adult male 05day    672 adult male 30day    485 adult female 01day    561 adult female 05day    428 adult female 30day    215 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    365 cold shock, 4-day adult    488 heat shock, 4-day adult    276 Cadmium 50 mM 6 hrs, larvae L3    680 Cadmium 50 mM 12 hrs, larvae L3    792 Cadmium 50 mM 48 hrs, 4-day adult    335 Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3    361 Copper 15 mM 48 hrs, 4-day adult    35 Zinc 5 mM 12 hrs, larvae L3    355 Zinc 4.5 mM 48 hrs, 4-day adult    113 Ethanol 2.5% 3 hrs, larvae L3    40 Ethanol 5% 3 hrs, larvae L3    614 Ethanol 10% 3 hrs, larvae L3    574 Caffeine 1.5 mg/ml 4 hrs, larvae L3    981 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    32 Caffeine 25 mg/ml 48 hrs, 4-day adult    270 Paraquat 5 mM 48 hrs, 4-day adult    95 Paraquat 10 mM 48 hrs, 4-day adult    225 Rotenone 2 μg 12 hrs, larvae L3    1017 Rotenone 8 μg 12 hrs, larvae L3    530 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (365) cold shock, 4-day adult  (488) heat shock, 4-day adult  (276) Cadmium 50 mM 6 hrs, larvae L3  (680) Cadmium 50 mM 12 hrs, larvae L3  (792) Cadmium 50 mM 48 hrs, 4-day adult  (335) Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3  (361) Copper 15 mM 48 hrs, 4-day adult  (35) Zinc 5 mM 12 hrs, larvae L3  (355) Zinc 4.5 mM 48 hrs, 4-day adult  (113) Ethanol 2.5% 3 hrs, larvae L3  (40) Ethanol 5% 3 hrs, larvae L3  (614) Ethanol 10% 3 hrs, larvae L3  (574) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (981) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (32) Caffeine 25 mg/ml 48 hrs, 4-day adult  (270) Paraquat 5 mM 48 hrs, 4-day adult  (95) Paraquat 10 mM 48 hrs, 4-day adult  (225) Rotenone 2 μg 12 hrs, larvae L3  (1017) Rotenone 8 μg 12 hrs, larvae L3  (530) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (365) cold shock, 4-day adult  (488) heat shock, 4-day adult  (276) Cadmium 50 mM 6 hrs, larvae L3  (680) Cadmium 50 mM 12 hrs, larvae L3  (792) Cadmium 50 mM 48 hrs, 4-day adult  (335) Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3  (361) Copper 15 mM 48 hrs, 4-day adult    35 Zinc 5 mM 12 hrs, larvae L3  (355) Zinc 4.5 mM 48 hrs, 4-day adult  (113) Ethanol 2.5% 3 hrs, larvae L3    40 Ethanol 5% 3 hrs, larvae L3  (614) Ethanol 10% 3 hrs, larvae L3  (574) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (981) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    32 Caffeine 25 mg/ml 48 hrs, 4-day adult  (270) Paraquat 5 mM 48 hrs, 4-day adult    95 Paraquat 10 mM 48 hrs, 4-day adult  (225) Rotenone 2 μg 12 hrs, larvae L3  (1017) Rotenone 8 μg 12 hrs, larvae L3  (530) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    365 cold shock, 4-day adult    488 heat shock, 4-day adult    276 Cadmium 50 mM 6 hrs, larvae L3    680 Cadmium 50 mM 12 hrs, larvae L3    792 Cadmium 50 mM 48 hrs, 4-day adult    335 Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3    361 Copper 15 mM 48 hrs, 4-day adult    35 Zinc 5 mM 12 hrs, larvae L3    355 Zinc 4.5 mM 48 hrs, 4-day adult    113 Ethanol 2.5% 3 hrs, larvae L3    40 Ethanol 5% 3 hrs, larvae L3    614 Ethanol 10% 3 hrs, larvae L3    574 Caffeine 1.5 mg/ml 4 hrs, larvae L3    981 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    32 Caffeine 25 mg/ml 48 hrs, 4-day adult    270 Paraquat 5 mM 48 hrs, 4-day adult    95 Paraquat 10 mM 48 hrs, 4-day adult    225 Rotenone 2 μg 12 hrs, larvae L3    1017 Rotenone 8 μg 12 hrs, larvae L3    530 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    365 cold shock, 4-day adult    488 heat shock, 4-day adult    276 Cadmium 50 mM 6 hrs, larvae L3    680 Cadmium 50 mM 12 hrs, larvae L3    792 Cadmium 50 mM 48 hrs, 4-day adult    335 Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3    361 Copper 15 mM 48 hrs, 4-day adult    35 Zinc 5 mM 12 hrs, larvae L3    355 Zinc 4.5 mM 48 hrs, 4-day adult    113 Ethanol 2.5% 3 hrs, larvae L3    40 Ethanol 5% 3 hrs, larvae L3    614 Ethanol 10% 3 hrs, larvae L3    574 Caffeine 1.5 mg/ml 4 hrs, larvae L3    981 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    32 Caffeine 25 mg/ml 48 hrs, 4-day adult    270 Paraquat 5 mM 48 hrs, 4-day adult    95 Paraquat 10 mM 48 hrs, 4-day adult    225 Rotenone 2 μg 12 hrs, larvae L3    1017 Rotenone 8 μg 12 hrs, larvae L3    530 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (365) cold shock, 4-day adult  (488) heat shock, 4-day adult  (276) Cadmium 50 mM 6 hrs, larvae L3  (680) Cadmium 50 mM 12 hrs, larvae L3  (792) Cadmium 50 mM 48 hrs, 4-day adult  (335) Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3  (361) Copper 15 mM 48 hrs, 4-day adult  (35) Zinc 5 mM 12 hrs, larvae L3  (355) Zinc 4.5 mM 48 hrs, 4-day adult  (113) Ethanol 2.5% 3 hrs, larvae L3  (40) Ethanol 5% 3 hrs, larvae L3  (614) Ethanol 10% 3 hrs, larvae L3  (574) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (981) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  32 Caffeine 25 mg/ml 48 hrs, 4-day adult  (270) Paraquat 5 mM 48 hrs, 4-day adult  (95) Paraquat 10 mM 48 hrs, 4-day adult  (225) Rotenone 2 μg 12 hrs, larvae L3  (1017) Rotenone 8 μg 12 hrs, larvae L3  (530) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  (365) cold shock, 4-day adult  (488) heat shock, 4-day adult  (276) Cadmium 50 mM 6 hrs, larvae L3  (680) Cadmium 50 mM 12 hrs, larvae L3  (792) Cadmium 50 mM 48 hrs, 4-day adult  (335) Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3  (361) Copper 15 mM 48 hrs, 4-day adult    35 Zinc 5 mM 12 hrs, larvae L3  (355) Zinc 4.5 mM 48 hrs, 4-day adult  113 Ethanol 2.5% 3 hrs, larvae L3    40 Ethanol 5% 3 hrs, larvae L3  (614) Ethanol 10% 3 hrs, larvae L3  (574) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (981) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    32 Caffeine 25 mg/ml 48 hrs, 4-day adult  (270) Paraquat 5 mM 48 hrs, 4-day adult    95 Paraquat 10 mM 48 hrs, 4-day adult  (225) Rotenone 2 μg 12 hrs, larvae L3  (1017) Rotenone 8 μg 12 hrs, larvae L3  (530) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    365 cold shock, 4-day adult    488 heat shock, 4-day adult    276 Cadmium 50 mM 6 hrs, larvae L3    680 Cadmium 50 mM 12 hrs, larvae L3    792 Cadmium 50 mM 48 hrs, 4-day adult    335 Cadmium 100 mM 48 hrs, 4-day adult    4 Copper 0.5 mM 12 hrs, larvae L3    361 Copper 15 mM 48 hrs, 4-day adult    35 Zinc 5 mM 12 hrs, larvae L3    355 Zinc 4.5 mM 48 hrs, 4-day adult    113 Ethanol 2.5% 3 hrs, larvae L3    40 Ethanol 5% 3 hrs, larvae L3    614 Ethanol 10% 3 hrs, larvae L3    574 Caffeine 1.5 mg/ml 4 hrs, larvae L3    981 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    32 Caffeine 25 mg/ml 48 hrs, 4-day adult    270 Paraquat 5 mM 48 hrs, 4-day adult    95 Paraquat 10 mM 48 hrs, 4-day adult    225 Rotenone 2 μg 12 hrs, larvae L3    1017 Rotenone 8 μg 12 hrs, larvae L3    530 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_16 mE1_20_mRNA_expression_cluster_16
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0028920 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8997-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG8997GD5384 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG8997 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG8997 Class Mutagen Stocks Known lesion CG8997GD5384 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG8997KK105510 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG8997NIG.8997R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(2L)Exel7059 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD5384} NA P{KK105510} NA P{NIG.8997R} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
	There is no information supporting a biological process, cellular component or molecular function term for this gene. (Based on a review of available data before: 2006)
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG8997 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 60829 DroID - A comprehensive database of gene and protein interactions. • FBgn0028920 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34799
Orthologs
OrthoDB Orthologs (18) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6KPTX7 Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search EOG6K0PJM Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6KPTX7)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG8997     Drosophila sechellia   Dsec\GM15045 Y   Drosophila erecta   Dere\GG10175 Y   Drosophila yakuba   Dyak\GE11368 Y   Drosophila ananassae   Dana\GF15613 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA21464 Y   Drosophila persimilis   Dper\GL21075 Y   Drosophila willistoni   Dwil\GK15116 Y   Drosophila virilis   Dvir\GJ18080 Y   Drosophila mojavensis   Dmoj\GI17402 Y   Drosophila grimshawi   Dgri\GH10611 Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (EOG6K0PJM)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Bombyx mori Silkmoth  Bmor\BGIBMGA010979 Y Bombyx mori Silkmoth  Bmor\BGIBMGA003323 Y Bombyx mori Silkmoth  Bmor\BGIBMGA014298 Y Bombyx mori Silkmoth  Bmor\Bmo.2551 Y Bombyx mori Silkmoth  Bmor\BGIBMGA003326 Y Bombyx mori Silkmoth  Bmor\BGIBMGA003325 Y Tribolium castaneum Red flour beetle  Tcas\TC013523 Y
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (10) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila sechellia Dsec\GM15045 Drosophila erecta Dere\GG10175 Drosophila yakuba Dyak\GE11368 Drosophila ananassae Dana\GF15613 Drosophila pseudoobscura pseudoobscura Dpse\GA21464 Drosophila persimilis Dper\GL21075 Drosophila willistoni Dwil\GK15116 Drosophila virilis Dvir\GJ18080 Drosophila mojavensis Dmoj\GI17402 Drosophila grimshawi Dgri\GH10611
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
VDRC	v101706 P{KK105510}VIE-260B v38023 w1118 P{GD5384}v38023 v45945 w1118; P{GD5384}v45945
Genomic Clones ( 1 )
	BACR16P12 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 34 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LP19506
Other clones	FI12201 TA01762
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LP07102 LP07749 LP11696 LP11861 LP18893 LP21584 LP21691 LP22205 LP23434
Other clones	14332 Dmel_dig_007366_0643_0828 Dmel_dig_009658_0644_0712 Dmel_dig_013175_0636_2315 Dmel_neb_011446_0117_0754 Dmel_neb_012063_0089_3383 Dmel_neb_013659_0446_1428 Dmel_neb_014634_0641_1194 Dmel_neb_015397_0831_0862 EC01376 EC13564 EC14739 EC24575 EC30202 EC31392 EC34502 EC35788 EC36988 EC39438 EC39975 EK116412 IP07319
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0028920 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34799
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_135837 RefSeq (Proteins) • NP_609681 DDBJ / EMBL / GenBank • AAF44828 AAF53345 AE003408 AI294389 L39629 Entrez Gene - A searchable database of RefSeq genes. • 34799 UniProtKB/TrEMBL • Q9V3A0
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Haemolymph juvenile hormone binding (IPR010562)
Linkouts
	BioGRID - A database of protein and genetic interactions • 60829 DroID - A comprehensive database of gene and protein interactions. • FBgn0028920 DRSC - Results from RNAi screens. • FBgn0028920 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0028920 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8997-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0028920 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 34799 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 34799 modMine - Data generated by the modENCODE project. • FBgn0028920
Synonyms & Secondary IDs ( 4 )
Reported As
Symbol Synonym	BG:DS00941.12 (Ashburner et al., 1999.10.12, Ashburner et al., 1999, Ashburner et al., 1999, Giot et al., 2003, ) CG8997 (Izutsu et al., 2012, Wittkopp et al., 2004, Müller et al., 2011, McGraw et al., 2008, Keleman et al., 2009.8.5, Wittkopp et al., 2008, King-Jones et al., 2006, Japanese National Institute of Genetics, 2012.5.21) CT25774 (Ceriani et al., 2002) DS00941.12 (Reese et al., 2000)
Name Synonym
Secondary FlyBase IDs
References ( 23 )
Generate a list of	All references relating to this gene ( 23 )
List References by type	Research paper  ( 9 ) Supplementary material  ( 6 ) Personal communication to FlyBase  ( 5 ) FlyBase analysis  ( 1 ) Stock list  ( 1 )
Recent research papers ( 2 )
	Izutsu et al., 2012, PLoS ONE 7(3): e33288 Genome features of "dark-fly", a Drosophila line reared long-term in a dark environment. [FBrf0217825] Müller et al., 2011, BMC Genomics 12(1): 81 Population transcriptomics of Drosophila melanogaster females. [FBrf0213050] Show all research papers ...