• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\miple2

General Information
Symbol	Dmel\miple2	Species	D. melanogaster
Name	miple2	Annotation symbol	CG18321
Feature type	protein_coding_gene	FlyBase ID	FBgn0029002
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	3L	Recombination map
Cytogenetic map	61B3-61B3	Sequence location	3L:271,200..275,018 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene miple2 is referred to in FlyBase by the symbol Dmel\miple2 (CG18321, FBgn0029002). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: heparin binding. The biological processes in which it is involved are not known. 7 alleles are reported. No phenotypic data is available. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Pleiotrophin/Midkine heparin-binding growth factor, C-terminal domain; Pleiotrophin/Midkine heparin-binding growth factor, disulphide-rich domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 06-18 hour embryonic stages, at stages throughout the pupal period. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval fat body. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval/adult midgut, larval Malpighian tubules, larval trachea. Comments on Affy2 ProbeSet: ProbeSet 1637645_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of miple2. Gene sequence location is 3L:271200..275018.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 61B3-61B3   Limits computationally determined from genome sequence between P{PZ}trh10512 and P{EP}EP3104EP3104
Experimentally Determined Cytological Location
Cytogenetic map Notes References 61A1-61A1     (Inohara, 1999.12.13)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\miple2 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.43 Gene model reviewed during 5.45 Low-frequency RNA-seq exon junction(s) not annotated. Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters. Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) miple2-RA FBtr0072506  NM_143739   1138   279 miple2-RD FBtr0332836  NM_001274269   1147   282 miple2-RE FBtr0332837  NM_001274270   1144   281 miple2-RF FBtr0332838  NM_001274271   1031   279 miple2-RG FBtr0332839  NM_001274272   1292   279
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein miple2-PA   FBpp0072406   30.5   279   10.97     NP_651996   AAF47369 miple2-PD   FBpp0305059   30.7   282   11.02     NP_001261198   AGB93893 miple2-PE   FBpp0305060   30.7   281   11.04     NP_001261199   AGB93894 miple2-PF   FBpp0305061   30.5   279   10.97     NP_001261200   AGB93895 miple2-PG   FBpp0305062   30.5   279   10.97     NP_001261201   AGB93896
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Pleiotrophin/Midkine heparin-binding growth factor, C-terminal domain (IPR020090) Pleiotrophin/Midkine heparin-binding growth factor, disulphide-rich domain (IPR020091)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA140682   AA140683   AE014296 AAF47369   AF215688 AAF22851   AE014296 AGB93893   AE014296 AGB93894   AE014296 AGB93895   AE014296 AGB93896   AY071054 AAL48676   BI166146   BI168332   BI168861   BI169202   BI169824   BI171999   BI215524   BI236696   BI240774   BI241853   BI351841   BI368440   BI368728   BI374147   BI486110   BI579696   BI580068   BT044311   CA807523   CK132536   CK657922   CK660710   CK661472   CO179561   CO183229   CO183237   CO184632   CO262113   CO294133   CO307390   CO307777   CO317221   CZ469505   CZ477051   CZ477550   CZ477551   DN154524   EC051616   EC053138   EC079611   EC081949   EC203646   EC204111   EC218808   EC223798   EC224368   EG974146   ES696244   ES696245   GH943562   GH951562   GH961318   GH979537
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9W0S4 Q9U3W4 Q8SZ83
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism | ubiquitous   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 7 -- 8   head mesoderm   (Fisher et al., 2012) hindgut anlage   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 9 -- 10   anterior endoderm   (Fisher et al., 2012) foregut primordium   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) inclusive hindgut primordium   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior endoderm   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) embryonic stage 11   mesoderm   (Englund et al., 2006) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) clypeo-labral primordium   (Fisher et al., 2012) dorsal pharyngeal muscle primordium   (Fisher et al., 2012) foregut primordium   (Fisher et al., 2012) hindgut proper primordium   (Fisher et al., 2012) longitudinal visceral muscle primordium   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) proventriculus primordium   (Fisher et al., 2012) somatic muscle primordium   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) visceral muscle primordium   (Fisher et al., 2012) embryonic stage 11 -- 17   endoderm   (Englund et al., 2006) embryonic stage 13 -- 16   embryonic anal pad   (Fisher et al., 2012) embryonic dorsal epidermis   (Fisher et al., 2012) embryonic foregut   (Fisher et al., 2012) embryonic hindgut   (Fisher et al., 2012) embryonic ventral epidermis   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) embryonic/larval muscle system   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) embryonic stage 14   organism | lateral   (Englund et al., 2006) embryonic stage 16 -- 17   ventral nerve cord | restricted   (Englund et al., 2006) Comment:midline cells
Additional Descriptive Data
	miple2 transcript is expressed at high levels in the endoderm from embryonic stage 11 through the end of embryogenesis, and in lower levels in the mesoderm at stage 11. At embryonic stage 14, miple2 is expressed in an unidentifed group of cells on the lateral side of the embryo. At embryonic stage 16, miple2 transcript is expressed in the midline cells of the ventral nerve cord. miple2 transcript is also maternally contributed to the embryo. (Englund et al., 2006)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
western blot Stage Tissue/Position (including subcellular localization) Reference     (Englund et al., 2006) Comment:assayed in cultured COS-7 cells
Additional Descriptive Data
	In cultured cells, miple2 protein is secreted into the culture medium. (Englund et al., 2006)
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
extracellular region inferred from direct assay (Englund et al., 2006)
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval fat body. Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, larval/adult midgut, larval Malpighian tubules, larval trachea. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    168.975 Larval Midgut    134.9 Larval Hindgut    65.3 Larval Malpighian Tubules    154.6 Larval Fat Body    866.6 Larval Salivary Gland    21.3 Larval Trachea    212.8 Larval Carcass    98.4 Adult Head    24.4 Adult Eye    17.95 Adult Brain    53.6 Adult Thoracic-Abdominal Ganglion    36.9 Adult Crop    6 Adult Midgut    312.8 Adult Hindgut    52 Adult Malpighian Tubules    60.4 Adult Fat Body    15.2 Adult Salivary Gland    12.7 Adult Heart    27.55 Adult VirginFemale Spermatheca    13.4 Adult InseminatedFemale Spermatheca    12.2 Adult Ovary    73.1 Adult Testis    68.1 Adult Male Accessory Gland    7.5 Adult Carcass    20.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    168.975 Larval Midgut    134.9 Larval Hindgut    65.3 Larval Malpighian Tubules    154.6 Larval Fat Body  (866.6) Larval Salivary Gland    21.3 Larval Trachea    212.8 Larval Carcass    98.4 Adult Head    24.4 Adult Eye    17.95 Adult Brain    53.6 Adult Thoracic-Abdominal Ganglion    36.9 Adult Crop    6 Adult Midgut    312.8 Adult Hindgut    52 Adult Malpighian Tubules    60.4 Adult Fat Body    15.2 Adult Salivary Gland    12.7 Adult Heart    27.55 Adult VirginFemale Spermatheca    13.4 Adult InseminatedFemale Spermatheca    12.2 Adult Ovary    73.1 Adult Testis    68.1 Adult Male Accessory Gland    7.5 Adult Carcass    20.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    168.975 Larval Midgut    134.9 Larval Hindgut    65.3 Larval Malpighian Tubules    154.6 Larval Fat Body    866.6 Larval Salivary Gland    21.3 Larval Trachea    212.8 Larval Carcass    98.4 Adult Head    24.4 Adult Eye    17.95 Adult Brain    53.6 Adult Thoracic-Abdominal Ganglion    36.9 Adult Crop    6 Adult Midgut    312.8 Adult Hindgut    52 Adult Malpighian Tubules    60.4 Adult Fat Body    15.2 Adult Salivary Gland    12.7 Adult Heart    27.55 Adult VirginFemale Spermatheca    13.4 Adult InseminatedFemale Spermatheca    12.2 Adult Ovary    73.1 Adult Testis    68.1 Adult Male Accessory Gland    7.5 Adult Carcass    20.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    168.975 Larval Midgut    134.9 Larval Hindgut    65.3 Larval Malpighian Tubules    154.6 Larval Fat Body    866.6 Larval Salivary Gland    21.3 Larval Trachea    212.8 Larval Carcass    98.4 Adult Head    24.4 Adult Eye    17.95 Adult Brain    53.6 Adult Thoracic-Abdominal Ganglion    36.9 Adult Crop    6 Adult Midgut    312.8 Adult Hindgut    52 Adult Malpighian Tubules    60.4 Adult Fat Body    15.2 Adult Salivary Gland    12.7 Adult Heart    27.55 Adult VirginFemale Spermatheca    13.4 Adult InseminatedFemale Spermatheca    12.2 Adult Ovary    73.1 Adult Testis    68.1 Adult Male Accessory Gland    7.5 Adult Carcass    20.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    168.975 Larval Midgut    134.9 Larval Hindgut    65.3 Larval Malpighian Tubules    154.6 Larval Fat Body    866.6 Larval Salivary Gland    21.3 Larval Trachea    212.8 Larval Carcass    98.4 Adult Head    24.4 Adult Eye    17.95 Adult Brain    53.6 Adult Thoracic-Abdominal Ganglion    36.9 Adult Crop    6 Adult Midgut    312.8 Adult Hindgut    52 Adult Malpighian Tubules    60.4 Adult Fat Body    15.2 Adult Salivary Gland    12.7 Adult Heart    27.55 Adult VirginFemale Spermatheca    13.4 Adult InseminatedFemale Spermatheca    12.2 Adult Ovary    73.1 Adult Testis    68.1 Adult Male Accessory Gland    7.5 Adult Carcass    20.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    168.975 Larval Midgut    134.9 Larval Hindgut    65.3 Larval Malpighian Tubules    154.6 Larval Fat Body  (866.6) Larval Salivary Gland    21.3 Larval Trachea    212.8 Larval Carcass    98.4 Adult Head    24.4 Adult Eye    17.95 Adult Brain    53.6 Adult Thoracic-Abdominal Ganglion    36.9 Adult Crop    6 Adult Midgut    312.8 Adult Hindgut    52 Adult Malpighian Tubules    60.4 Adult Fat Body    15.2 Adult Salivary Gland    12.7 Adult Heart    27.55 Adult VirginFemale Spermatheca    13.4 Adult InseminatedFemale Spermatheca    12.2 Adult Ovary    73.1 Adult Testis    68.1 Adult Male Accessory Gland    7.5 Adult Carcass    20.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    168.975 Larval Midgut    134.9 Larval Hindgut    65.3 Larval Malpighian Tubules    154.6 Larval Fat Body    866.6 Larval Salivary Gland    21.3 Larval Trachea    212.8 Larval Carcass    98.4 Adult Head    24.4 Adult Eye    17.95 Adult Brain    53.6 Adult Thoracic-Abdominal Ganglion    36.9 Adult Crop    6 Adult Midgut    312.8 Adult Hindgut    52 Adult Malpighian Tubules    60.4 Adult Fat Body    15.2 Adult Salivary Gland    12.7 Adult Heart    27.55 Adult VirginFemale Spermatheca    13.4 Adult InseminatedFemale Spermatheca    12.2 Adult Ovary    73.1 Adult Testis    68.1 Adult Male Accessory Gland    7.5 Adult Carcass    20.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    168.975 Larval Midgut    134.9 Larval Hindgut    65.3 Larval Malpighian Tubules    154.6 Larval Fat Body    866.6 Larval Salivary Gland    21.3 Larval Trachea    212.8 Larval Carcass    98.4 Adult Head    24.4 Adult Eye    17.95 Adult Brain    53.6 Adult Thoracic-Abdominal Ganglion    36.9 Adult Crop    6 Adult Midgut    312.8 Adult Hindgut    52 Adult Malpighian Tubules    60.4 Adult Fat Body    15.2 Adult Salivary Gland    12.7 Adult Heart    27.55 Adult VirginFemale Spermatheca    13.4 Adult InseminatedFemale Spermatheca    12.2 Adult Ovary    73.1 Adult Testis    68.1 Adult Male Accessory Gland    7.5 Adult Carcass    20.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    24.4   NA  Eye    17.95   NA  Brain    53.6   168.975  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    36.9   NA  Crop    6   134.9  Midgut    312.8   65.3  Hindgut    52   154.6  Malpighian Tubules    60.4   866.6  Fat Body    no informative data   21.3  Salivary Gland    no informative data   NA  Heart    27.55   212.8  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    73.1   NA  Testis    68.1   NA  Male Accessory Gland    7.5   98.4  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    157 central nervous system, larvae L3    71 central nervous system, pupae P8    102 head, virgin 1-day female    22 head, virgin 4-day female    5 head, virgin 20-day female    2 head, mated 1-day female    18 head, mated 4-day female    6 head, mated 20-day female    3 head, mated 1-day male    21 head, mated 4-day male    9 head, mated 20-day male    8 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    64 digestive system, larvae L3 wandering    127 digestive system, 1-day adult    28 digestive system, 4-day adult    36 digestive system, 20-day adult    38 fat body, larvae L3 wandering    120 fat body, white prepupae    430 fat body, pupae P8    305 carcass, larvae L3 wandering    160 carcass, 1-day adult    11 carcass, 4-day adult    5 carcass, 20-day adult    4 ovary, virgin 4-day female    30 ovary, mated 4-day female    39 testis, mated 4-day male    18 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (157) central nervous system, larvae L3  (71) central nervous system, pupae P8  (102) head, virgin 1-day female    22 head, virgin 4-day female    5 head, virgin 20-day female    2 head, mated 1-day female    18 head, mated 4-day female    6 head, mated 20-day female    3 head, mated 1-day male    21 head, mated 4-day male    9 head, mated 20-day male    8 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae  (64) digestive system, larvae L3 wandering  (127) digestive system, 1-day adult  (28) digestive system, 4-day adult  (36) digestive system, 20-day adult  (38) fat body, larvae L3 wandering  (120) fat body, white prepupae  (430) fat body, pupae P8  (305) carcass, larvae L3 wandering  (160) carcass, 1-day adult    11 carcass, 4-day adult    5 carcass, 20-day adult    4 ovary, virgin 4-day female  (30) ovary, mated 4-day female  (39) testis, mated 4-day male    18 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (157) central nervous system, larvae L3    71 central nervous system, pupae P8  102 head, virgin 1-day female    22 head, virgin 4-day female    5 head, virgin 20-day female    2 head, mated 1-day female    18 head, mated 4-day female    6 head, mated 20-day female    3 head, mated 1-day male    21 head, mated 4-day male    9 head, mated 20-day male    8 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    64 digestive system, larvae L3 wandering  (127) digestive system, 1-day adult    28 digestive system, 4-day adult    36 digestive system, 20-day adult    38 fat body, larvae L3 wandering  (120) fat body, white prepupae  (430) fat body, pupae P8  (305) carcass, larvae L3 wandering  (160) carcass, 1-day adult    11 carcass, 4-day adult    5 carcass, 20-day adult    4 ovary, virgin 4-day female    30 ovary, mated 4-day female    39 testis, mated 4-day male    18 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    157 central nervous system, larvae L3    71 central nervous system, pupae P8    102 head, virgin 1-day female    22 head, virgin 4-day female    5 head, virgin 20-day female    2 head, mated 1-day female    18 head, mated 4-day female    6 head, mated 20-day female    3 head, mated 1-day male    21 head, mated 4-day male    9 head, mated 20-day male    8 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    64 digestive system, larvae L3 wandering    127 digestive system, 1-day adult    28 digestive system, 4-day adult    36 digestive system, 20-day adult    38 fat body, larvae L3 wandering    120 fat body, white prepupae    430 fat body, pupae P8    305 carcass, larvae L3 wandering    160 carcass, 1-day adult    11 carcass, 4-day adult    5 carcass, 20-day adult    4 ovary, virgin 4-day female    30 ovary, mated 4-day female    39 testis, mated 4-day male    18 accessory gland, mated 4-day male    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    157 central nervous system, larvae L3    71 central nervous system, pupae P8    102 head, virgin 1-day female    22 head, virgin 4-day female    5 head, virgin 20-day female    2 head, mated 1-day female    18 head, mated 4-day female    6 head, mated 20-day female    3 head, mated 1-day male    21 head, mated 4-day male    9 head, mated 20-day male    8 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    64 digestive system, larvae L3 wandering    127 digestive system, 1-day adult    28 digestive system, 4-day adult    36 digestive system, 20-day adult    38 fat body, larvae L3 wandering    120 fat body, white prepupae    430 fat body, pupae P8    305 carcass, larvae L3 wandering    160 carcass, 1-day adult    11 carcass, 4-day adult    5 carcass, 20-day adult    4 ovary, virgin 4-day female    30 ovary, mated 4-day female    39 testis, mated 4-day male    18 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (157) central nervous system, larvae L3  (71) central nervous system, pupae P8  (102) head, virgin 1-day female    22 head, virgin 4-day female    5 head, virgin 20-day female    2 head, mated 1-day female    18 head, mated 4-day female    6 head, mated 20-day female    3 head, mated 1-day male    21 head, mated 4-day male    9 head, mated 20-day male    8 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae  (64) digestive system, larvae L3 wandering  (127) digestive system, 1-day adult  28 digestive system, 4-day adult  (36) digestive system, 20-day adult  (38) fat body, larvae L3 wandering  (120) fat body, white prepupae  (430) fat body, pupae P8  (305) carcass, larvae L3 wandering  (160) carcass, 1-day adult    11 carcass, 4-day adult    5 carcass, 20-day adult    4 ovary, virgin 4-day female  30 ovary, mated 4-day female  (39) testis, mated 4-day male    18 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (157) central nervous system, larvae L3    71 central nervous system, pupae P8  102 head, virgin 1-day female    22 head, virgin 4-day female    5 head, virgin 20-day female    2 head, mated 1-day female    18 head, mated 4-day female    6 head, mated 20-day female    3 head, mated 1-day male    21 head, mated 4-day male    9 head, mated 20-day male    8 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    64 digestive system, larvae L3 wandering  127 digestive system, 1-day adult    28 digestive system, 4-day adult    36 digestive system, 20-day adult    38 fat body, larvae L3 wandering  120 fat body, white prepupae  (430) fat body, pupae P8  (305) carcass, larvae L3 wandering  (160) carcass, 1-day adult    11 carcass, 4-day adult    5 carcass, 20-day adult    4 ovary, virgin 4-day female    30 ovary, mated 4-day female    39 testis, mated 4-day male    18 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    157 central nervous system, larvae L3    71 central nervous system, pupae P8    102 head, virgin 1-day female    22 head, virgin 4-day female    5 head, virgin 20-day female    2 head, mated 1-day female    18 head, mated 4-day female    6 head, mated 20-day female    3 head, mated 1-day male    21 head, mated 4-day male    9 head, mated 20-day male    8 salivary gland, larvae L3 wandering    10 salivary gland, white prepupae    64 digestive system, larvae L3 wandering    127 digestive system, 1-day adult    28 digestive system, 4-day adult    36 digestive system, 20-day adult    38 fat body, larvae L3 wandering    120 fat body, white prepupae    430 fat body, pupae P8    305 carcass, larvae L3 wandering    160 carcass, 1-day adult    11 carcass, 4-day adult    5 carcass, 20-day adult    4 ovary, virgin 4-day female    30 ovary, mated 4-day female    39 testis, mated 4-day male    18 accessory gland, mated 4-day male    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 06-18 hour embryonic stages, at stages throughout the pupal period. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    16 embryo 04-06hr    57 embryo 06-08hr    128 embryo 08-10hr    122 embryo 10-12hr    125 embryo 12-14hr    150 embryo 14-16hr    75 embryo 16-18hr    64 embryo 18-20hr    35 embryo 20-22hr    13 embryo 22-24hr    18 larva L1    11 larva L2    8 larva L3 12hr old    8 larva L3 puffstage 1-2    20 larva L3 puffstage 3-6    46 larva L3 puffstage 7-9    86 white prepupae new    132 white prepupae 12hr    94 white prepupae 24hr    167 pupae 2d postWPP    122 pupae 3d postWPP    45 pupae 4d postWPP    11 adult male 01day    13 adult male 05day    6 adult male 30day    5 adult female 01day    13 adult female 05day    7 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    16 embryo 04-06hr  (57) embryo 06-08hr  (128) embryo 08-10hr  (122) embryo 10-12hr  (125) embryo 12-14hr  (150) embryo 14-16hr  (75) embryo 16-18hr  (64) embryo 18-20hr  (35) embryo 20-22hr    13 embryo 22-24hr    18 larva L1    11 larva L2    8 larva L3 12hr old    8 larva L3 puffstage 1-2    20 larva L3 puffstage 3-6  (46) larva L3 puffstage 7-9  (86) white prepupae new  (132) white prepupae 12hr  (94) white prepupae 24hr  (167) pupae 2d postWPP  (122) pupae 3d postWPP  (45) pupae 4d postWPP    11 adult male 01day    13 adult male 05day    6 adult male 30day    5 adult female 01day    13 adult female 05day    7 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    16 embryo 04-06hr    57 embryo 06-08hr  (128) embryo 08-10hr  (122) embryo 10-12hr  (125) embryo 12-14hr  (150) embryo 14-16hr    75 embryo 16-18hr    64 embryo 18-20hr    35 embryo 20-22hr    13 embryo 22-24hr    18 larva L1    11 larva L2    8 larva L3 12hr old    8 larva L3 puffstage 1-2    20 larva L3 puffstage 3-6    46 larva L3 puffstage 7-9    86 white prepupae new  (132) white prepupae 12hr    94 white prepupae 24hr  (167) pupae 2d postWPP  (122) pupae 3d postWPP    45 pupae 4d postWPP    11 adult male 01day    13 adult male 05day    6 adult male 30day    5 adult female 01day    13 adult female 05day    7 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    16 embryo 04-06hr    57 embryo 06-08hr    128 embryo 08-10hr    122 embryo 10-12hr    125 embryo 12-14hr    150 embryo 14-16hr    75 embryo 16-18hr    64 embryo 18-20hr    35 embryo 20-22hr    13 embryo 22-24hr    18 larva L1    11 larva L2    8 larva L3 12hr old    8 larva L3 puffstage 1-2    20 larva L3 puffstage 3-6    46 larva L3 puffstage 7-9    86 white prepupae new    132 white prepupae 12hr    94 white prepupae 24hr    167 pupae 2d postWPP    122 pupae 3d postWPP    45 pupae 4d postWPP    11 adult male 01day    13 adult male 05day    6 adult male 30day    5 adult female 01day    13 adult female 05day    7 adult female 30day    8 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    16 embryo 04-06hr    57 embryo 06-08hr    128 embryo 08-10hr    122 embryo 10-12hr    125 embryo 12-14hr    150 embryo 14-16hr    75 embryo 16-18hr    64 embryo 18-20hr    35 embryo 20-22hr    13 embryo 22-24hr    18 larva L1    11 larva L2    8 larva L3 12hr old    8 larva L3 puffstage 1-2    20 larva L3 puffstage 3-6    46 larva L3 puffstage 7-9    86 white prepupae new    132 white prepupae 12hr    94 white prepupae 24hr    167 pupae 2d postWPP    122 pupae 3d postWPP    45 pupae 4d postWPP    11 adult male 01day    13 adult male 05day    6 adult male 30day    5 adult female 01day    13 adult female 05day    7 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    16 embryo 04-06hr  (57) embryo 06-08hr  (128) embryo 08-10hr  (122) embryo 10-12hr  (125) embryo 12-14hr  (150) embryo 14-16hr  (75) embryo 16-18hr  (64) embryo 18-20hr  (35) embryo 20-22hr    13 embryo 22-24hr    18 larva L1    11 larva L2    8 larva L3 12hr old    8 larva L3 puffstage 1-2    20 larva L3 puffstage 3-6  (46) larva L3 puffstage 7-9  (86) white prepupae new  (132) white prepupae 12hr  (94) white prepupae 24hr  (167) pupae 2d postWPP  (122) pupae 3d postWPP  (45) pupae 4d postWPP    11 adult male 01day    13 adult male 05day    6 adult male 30day    5 adult female 01day    13 adult female 05day    7 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    16 embryo 04-06hr    57 embryo 06-08hr  128 embryo 08-10hr  122 embryo 10-12hr  125 embryo 12-14hr  (150) embryo 14-16hr    75 embryo 16-18hr    64 embryo 18-20hr    35 embryo 20-22hr    13 embryo 22-24hr    18 larva L1    11 larva L2    8 larva L3 12hr old    8 larva L3 puffstage 1-2    20 larva L3 puffstage 3-6    46 larva L3 puffstage 7-9    86 white prepupae new  132 white prepupae 12hr    94 white prepupae 24hr  (167) pupae 2d postWPP  122 pupae 3d postWPP    45 pupae 4d postWPP    11 adult male 01day    13 adult male 05day    6 adult male 30day    5 adult female 01day    13 adult female 05day    7 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4 embryo 02-04hr    16 embryo 04-06hr    57 embryo 06-08hr    128 embryo 08-10hr    122 embryo 10-12hr    125 embryo 12-14hr    150 embryo 14-16hr    75 embryo 16-18hr    64 embryo 18-20hr    35 embryo 20-22hr    13 embryo 22-24hr    18 larva L1    11 larva L2    8 larva L3 12hr old    8 larva L3 puffstage 1-2    20 larva L3 puffstage 3-6    46 larva L3 puffstage 7-9    86 white prepupae new    132 white prepupae 12hr    94 white prepupae 24hr    167 pupae 2d postWPP    122 pupae 3d postWPP    45 pupae 4d postWPP    11 adult male 01day    13 adult male 05day    6 adult male 30day    5 adult female 01day    13 adult female 05day    7 adult female 30day    8 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    139 Schneider line 2 Sg4    357 embryonic 1182-4H    429 embryonic GM2    167 embryonic Kc167    150 embryonic S1    53 embryonic S3    1223 leg disc CME L1    552 wing disc CME-W2    176 wing disc ML-DmD8    567 wing disc ML-DmD9    84 wing disc ML-DmD16-c3    283 wing disc ML-DmD21    301 wing disc ML-DmD32    72 haltere disc ML-DmD17-c3    116 eye-antennal disc ML-DmD11    174 antennal disc ML-DmD20-c5    188 mixed discs ML-DmD4-c1    680 CNS ML-DmBG1-c1    175 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    63 ovary fGS/OSS    527 ovary OSC    576 ovary OSS    249 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (139) Schneider line 2 Sg4  (357) embryonic 1182-4H  (429) embryonic GM2  (167) embryonic Kc167  (150) embryonic S1  (53) embryonic S3  (1223) leg disc CME L1  (552) wing disc CME-W2  (176) wing disc ML-DmD8  (567) wing disc ML-DmD9  (84) wing disc ML-DmD16-c3  (283) wing disc ML-DmD21  (301) wing disc ML-DmD32  (72) haltere disc ML-DmD17-c3  (116) eye-antennal disc ML-DmD11  (174) antennal disc ML-DmD20-c5  (188) mixed discs ML-DmD4-c1  (680) CNS ML-DmBG1-c1  (175) CNS ML-DmBG2-c2    7 tumorous blood cells mbn2  (63) ovary fGS/OSS  (527) ovary OSC  (576) ovary OSS  (249) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (139) Schneider line 2 Sg4  (357) embryonic 1182-4H  (429) embryonic GM2  (167) embryonic Kc167  (150) embryonic S1    53 embryonic S3  (1223) leg disc CME L1  (552) wing disc CME-W2  (176) wing disc ML-DmD8  (567) wing disc ML-DmD9    84 wing disc ML-DmD16-c3  (283) wing disc ML-DmD21  (301) wing disc ML-DmD32    72 haltere disc ML-DmD17-c3  (116) eye-antennal disc ML-DmD11  (174) antennal disc ML-DmD20-c5  (188) mixed discs ML-DmD4-c1  (680) CNS ML-DmBG1-c1  (175) CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    63 ovary fGS/OSS  (527) ovary OSC  (576) ovary OSS  (249) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    139 Schneider line 2 Sg4    357 embryonic 1182-4H    429 embryonic GM2    167 embryonic Kc167    150 embryonic S1    53 embryonic S3    1223 leg disc CME L1    552 wing disc CME-W2    176 wing disc ML-DmD8    567 wing disc ML-DmD9    84 wing disc ML-DmD16-c3    283 wing disc ML-DmD21    301 wing disc ML-DmD32    72 haltere disc ML-DmD17-c3    116 eye-antennal disc ML-DmD11    174 antennal disc ML-DmD20-c5    188 mixed discs ML-DmD4-c1    680 CNS ML-DmBG1-c1    175 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    63 ovary fGS/OSS    527 ovary OSC    576 ovary OSS    249 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    139 Schneider line 2 Sg4    357 embryonic 1182-4H    429 embryonic GM2    167 embryonic Kc167    150 embryonic S1    53 embryonic S3    1223 leg disc CME L1    552 wing disc CME-W2    176 wing disc ML-DmD8    567 wing disc ML-DmD9    84 wing disc ML-DmD16-c3    283 wing disc ML-DmD21    301 wing disc ML-DmD32    72 haltere disc ML-DmD17-c3    116 eye-antennal disc ML-DmD11    174 antennal disc ML-DmD20-c5    188 mixed discs ML-DmD4-c1    680 CNS ML-DmBG1-c1    175 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    63 ovary fGS/OSS    527 ovary OSC    576 ovary OSS    249 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (139) Schneider line 2 Sg4  (357) embryonic 1182-4H  (429) embryonic GM2  (167) embryonic Kc167  (150) embryonic S1  (53) embryonic S3  (1223) leg disc CME L1  (552) wing disc CME-W2  (176) wing disc ML-DmD8  (567) wing disc ML-DmD9  (84) wing disc ML-DmD16-c3  (283) wing disc ML-DmD21  (301) wing disc ML-DmD32  (72) haltere disc ML-DmD17-c3  (116) eye-antennal disc ML-DmD11  (174) antennal disc ML-DmD20-c5  (188) mixed discs ML-DmD4-c1  (680) CNS ML-DmBG1-c1  (175) CNS ML-DmBG2-c2    7 tumorous blood cells mbn2  (63) ovary fGS/OSS  (527) ovary OSC  (576) ovary OSS  (249) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  139 Schneider line 2 Sg4  (357) embryonic 1182-4H  (429) embryonic GM2  (167) embryonic Kc167  (150) embryonic S1    53 embryonic S3  (1223) leg disc CME L1  (552) wing disc CME-W2  (176) wing disc ML-DmD8  (567) wing disc ML-DmD9    84 wing disc ML-DmD16-c3  (283) wing disc ML-DmD21  (301) wing disc ML-DmD32    72 haltere disc ML-DmD17-c3  116 eye-antennal disc ML-DmD11  (174) antennal disc ML-DmD20-c5  (188) mixed discs ML-DmD4-c1  (680) CNS ML-DmBG1-c1  (175) CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    63 ovary fGS/OSS  (527) ovary OSC  (576) ovary OSS  (249) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    139 Schneider line 2 Sg4    357 embryonic 1182-4H    429 embryonic GM2    167 embryonic Kc167    150 embryonic S1    53 embryonic S3    1223 leg disc CME L1    552 wing disc CME-W2    176 wing disc ML-DmD8    567 wing disc ML-DmD9    84 wing disc ML-DmD16-c3    283 wing disc ML-DmD21    301 wing disc ML-DmD32    72 haltere disc ML-DmD17-c3    116 eye-antennal disc ML-DmD11    174 antennal disc ML-DmD20-c5    188 mixed discs ML-DmD4-c1    680 CNS ML-DmBG1-c1    175 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    63 ovary fGS/OSS    527 ovary OSC    576 ovary OSS    249 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    71 cold shock, 4-day adult    64 heat shock, 4-day adult    21 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    88 Cadmium 50 mM 48 hrs, 4-day adult    26 Cadmium 100 mM 48 hrs, 4-day adult    42 Copper 0.5 mM 12 hrs, larvae L3    74 Copper 15 mM 48 hrs, 4-day adult    45 Zinc 5 mM 12 hrs, larvae L3    64 Zinc 4.5 mM 48 hrs, 4-day adult    45 Ethanol 2.5% 3 hrs, larvae L3    26 Ethanol 5% 3 hrs, larvae L3    22 Ethanol 10% 3 hrs, larvae L3    20 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    36 Caffeine 25 mg/ml 48 hrs, 4-day adult    69 Paraquat 5 mM 48 hrs, 4-day adult    30 Paraquat 10 mM 48 hrs, 4-day adult    32 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (71) cold shock, 4-day adult  (64) heat shock, 4-day adult    21 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3  (88) Cadmium 50 mM 48 hrs, 4-day adult  26 Cadmium 100 mM 48 hrs, 4-day adult  (42) Copper 0.5 mM 12 hrs, larvae L3  (74) Copper 15 mM 48 hrs, 4-day adult  (45) Zinc 5 mM 12 hrs, larvae L3  (64) Zinc 4.5 mM 48 hrs, 4-day adult  (45) Ethanol 2.5% 3 hrs, larvae L3  26 Ethanol 5% 3 hrs, larvae L3    22 Ethanol 10% 3 hrs, larvae L3    20 Caffeine 1.5 mg/ml 4 hrs, larvae L3  (27) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (36) Caffeine 25 mg/ml 48 hrs, 4-day adult  (69) Paraquat 5 mM 48 hrs, 4-day adult  (30) Paraquat 10 mM 48 hrs, 4-day adult  (32) Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    71 cold shock, 4-day adult    64 heat shock, 4-day adult    21 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    88 Cadmium 50 mM 48 hrs, 4-day adult    26 Cadmium 100 mM 48 hrs, 4-day adult    42 Copper 0.5 mM 12 hrs, larvae L3    74 Copper 15 mM 48 hrs, 4-day adult    45 Zinc 5 mM 12 hrs, larvae L3    64 Zinc 4.5 mM 48 hrs, 4-day adult    45 Ethanol 2.5% 3 hrs, larvae L3    26 Ethanol 5% 3 hrs, larvae L3    22 Ethanol 10% 3 hrs, larvae L3    20 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    36 Caffeine 25 mg/ml 48 hrs, 4-day adult    69 Paraquat 5 mM 48 hrs, 4-day adult    30 Paraquat 10 mM 48 hrs, 4-day adult    32 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    71 cold shock, 4-day adult    64 heat shock, 4-day adult    21 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    88 Cadmium 50 mM 48 hrs, 4-day adult    26 Cadmium 100 mM 48 hrs, 4-day adult    42 Copper 0.5 mM 12 hrs, larvae L3    74 Copper 15 mM 48 hrs, 4-day adult    45 Zinc 5 mM 12 hrs, larvae L3    64 Zinc 4.5 mM 48 hrs, 4-day adult    45 Ethanol 2.5% 3 hrs, larvae L3    26 Ethanol 5% 3 hrs, larvae L3    22 Ethanol 10% 3 hrs, larvae L3    20 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    36 Caffeine 25 mg/ml 48 hrs, 4-day adult    69 Paraquat 5 mM 48 hrs, 4-day adult    30 Paraquat 10 mM 48 hrs, 4-day adult    32 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    71 cold shock, 4-day adult    64 heat shock, 4-day adult    21 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    88 Cadmium 50 mM 48 hrs, 4-day adult    26 Cadmium 100 mM 48 hrs, 4-day adult    42 Copper 0.5 mM 12 hrs, larvae L3    74 Copper 15 mM 48 hrs, 4-day adult    45 Zinc 5 mM 12 hrs, larvae L3    64 Zinc 4.5 mM 48 hrs, 4-day adult    45 Ethanol 2.5% 3 hrs, larvae L3    26 Ethanol 5% 3 hrs, larvae L3    22 Ethanol 10% 3 hrs, larvae L3    20 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    36 Caffeine 25 mg/ml 48 hrs, 4-day adult    69 Paraquat 5 mM 48 hrs, 4-day adult    30 Paraquat 10 mM 48 hrs, 4-day adult    32 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (71) cold shock, 4-day adult  (64) heat shock, 4-day adult    21 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3  (88) Cadmium 50 mM 48 hrs, 4-day adult  26 Cadmium 100 mM 48 hrs, 4-day adult  (42) Copper 0.5 mM 12 hrs, larvae L3  (74) Copper 15 mM 48 hrs, 4-day adult  (45) Zinc 5 mM 12 hrs, larvae L3  (64) Zinc 4.5 mM 48 hrs, 4-day adult  (45) Ethanol 2.5% 3 hrs, larvae L3  26 Ethanol 5% 3 hrs, larvae L3    22 Ethanol 10% 3 hrs, larvae L3    20 Caffeine 1.5 mg/ml 4 hrs, larvae L3  27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (36) Caffeine 25 mg/ml 48 hrs, 4-day adult  (69) Paraquat 5 mM 48 hrs, 4-day adult  30 Paraquat 10 mM 48 hrs, 4-day adult  32 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    71 cold shock, 4-day adult    64 heat shock, 4-day adult    21 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    88 Cadmium 50 mM 48 hrs, 4-day adult    26 Cadmium 100 mM 48 hrs, 4-day adult    42 Copper 0.5 mM 12 hrs, larvae L3    74 Copper 15 mM 48 hrs, 4-day adult    45 Zinc 5 mM 12 hrs, larvae L3    64 Zinc 4.5 mM 48 hrs, 4-day adult    45 Ethanol 2.5% 3 hrs, larvae L3    26 Ethanol 5% 3 hrs, larvae L3    22 Ethanol 10% 3 hrs, larvae L3    20 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    36 Caffeine 25 mg/ml 48 hrs, 4-day adult    69 Paraquat 5 mM 48 hrs, 4-day adult    30 Paraquat 10 mM 48 hrs, 4-day adult    32 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    71 cold shock, 4-day adult    64 heat shock, 4-day adult    21 Cadmium 50 mM 6 hrs, larvae L3    24 Cadmium 50 mM 12 hrs, larvae L3    88 Cadmium 50 mM 48 hrs, 4-day adult    26 Cadmium 100 mM 48 hrs, 4-day adult    42 Copper 0.5 mM 12 hrs, larvae L3    74 Copper 15 mM 48 hrs, 4-day adult    45 Zinc 5 mM 12 hrs, larvae L3    64 Zinc 4.5 mM 48 hrs, 4-day adult    45 Ethanol 2.5% 3 hrs, larvae L3    26 Ethanol 5% 3 hrs, larvae L3    22 Ethanol 10% 3 hrs, larvae L3    20 Caffeine 1.5 mg/ml 4 hrs, larvae L3    27 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    36 Caffeine 25 mg/ml 48 hrs, 4-day adult    69 Paraquat 5 mM 48 hrs, 4-day adult    30 Paraquat 10 mM 48 hrs, 4-day adult    32 Rotenone 2 μg 12 hrs, larvae L3    21 Rotenone 8 μg 12 hrs, larvae L3    7 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_11
External Data & Images
Linkouts	BDGP expression data • RE13914 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0029002 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG18321-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for miple2 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable miple2c04774 viable, with Scer\GAL4pnr-MD237 miple2GD12721 Sterility Allele fertile miple2c04774 Phenotype manifest in Allele
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of miple2 Class Mutagen Stocks Known lesion miple2c04774 piggyBac transposase 1 -- miple2MI04602 1 -- miple2d10006 P-element activity 0 -- miple2d11098 P-element activity 0 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of miple2 Class Mutagen Stocks Known lesion miple2GD12721 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes miple2KK103591 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes miple2NIG.18321R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(3L)Exel6084 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD12721} NA P{KK103591} NA P{NIG.18321R} NA GAL4 construct P{miple2-GAL4.W} No
Insertions
	Type of insertions Name Expression data miscellaneous insertions Mi{MIC}miple2MI04602 NA PBac{PB}miple2c04774 NA insertion of mobile activating element P{EPgy2}EY04126 NA P{XP}miple2d10006 NA P{XP}miple2d11098 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
	There is no information supporting a biological process term for this gene. (Based on a review of available data on: 2009-10-29)
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
extracellular region inferred from direct assay (Englund et al., 2006)
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
growth factor activity inferred from electronic annotation with InterPro:IPR020090, InterPro:IPR020091 (FlyBase Curators et al., 2004-) heparin binding inferred from sequence or structural similarity with human MDK (Englund et al., 2006)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
miple2 - CG32278 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) miple2 - CG4825 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) miple2 - CG4847 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) miple2 - CG7920 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) miple2 - CG8336 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) miple2 - CG8379 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) miple2 - CG8939 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) miple2 - CG9114 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) miple2 - DNApol-ι anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) miple2 - E(spl)mδ-HLH anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) miple2 - EndoG anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) miple2 - Ipk1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) miple2 - Rab10 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) miple2 - Rcc1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) miple2 - Snr1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) miple2 - Vps25 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) miple2 - gcl anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) miple2 - nopo anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) miple2 - twe anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions miple2 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0029002
Orthologs
OrthoDB Orthologs (31) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6NZVF0 Dipteran inclusive ortholog search EOG6BP1MZ Insect inclusive ortholog search EOG62Z3MD Arthropod inclusive ortholog search EOG6QJQ4D Metazoa inclusive ortholog search EOG6QK4GV
Orthologs in Drosophila Species (EOG6NZVF0)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\miple2     Drosophila simulans   Dsim\GD11007 Y   Drosophila sechellia   Dsec\GM14327 Y   Drosophila erecta   Dere\GG14711 Y   Drosophila yakuba   Dyak\GE21074 Y   Drosophila ananassae   Dana\GF25045 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA14888 Y   Drosophila persimilis   Dper\GL16125 Y   Drosophila willistoni   Dwil\GK16544 Y   Drosophila virilis   Dvir\GJ16095 Y   Drosophila mojavensis   Dmoj\GI12796 Y   Drosophila grimshawi   Dgri\GH15739 Y
Orthologs in non-Drosophila Dipterans (EOG6BP1MZ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL000288 Y Anopheles gambiae Malaria mosquito  Agam\AGAP005674 Y Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ006934 Y
Orthologs in non-Dipteran Insects (EOG62Z3MD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC551031 Y Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG014948 Y Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH15319 Y Atta cephalotes Leafcutter ant  Acep\ACEP16560 Y Camponotus floridanus Florida carpenter ant  Cflo\CFLO21003 Y Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL12719 Y Linepithema humile Argentine ant  Lhum\LH21651 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB10682 Y Pogonomyrmex barbatus Red harvester ant  Pbar\PB25694 Y Acyrthosiphon pisum Pea aphid  Apim\ACYPI34442 Y Bombyx mori Silkmoth  Bmor\BGIBMGA000590 Y Pediculus humanus Human body louse  Phum\PHUM530370 Y Tribolium castaneum Red flour beetle  Tcas\TC003391 Y
Orthologs in non-Insect Arthropods (EOG6QJQ4D)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_99314 Y Ixodes scapularis Deer tick  Isca\ISCW023508 Y
Orthologs in non-Arthropod Metazoa (EOG6QK4GV)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_016397gn Y
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD11007 Drosophila sechellia Dsec\GM14327 Drosophila erecta Dere\GG14711 Drosophila yakuba Dyak\GE21074 Drosophila ananassae Dana\GF25045 Drosophila pseudoobscura pseudoobscura Dpse\GA14888 Drosophila persimilis Dper\GL16125 Drosophila willistoni Dwil\GK16544 Drosophila virilis Dvir\GJ16095 Drosophila mojavensis Dmoj\GI12796 Drosophila grimshawi Dgri\GH15739
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	11605 w1118; PBac{PB}miple2c04774 37963 y1 w*; Mi{MIC}miple2MI04602 CG32845MI04602/TM3, Sb1 Ser1
VDRC	v102644 P{KK103591}VIE-260B v39025 w1118; P{GD12721}v39025 v39026 w1118; P{GD12721}v39026
Genomic Clones ( 2 )
	BACR11J11 BACR13F06 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 47 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE13914
Other clones	FI07208
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM16350 LP14120 LP19528 LP21006 RE06178 RE09041 RE09755 RE10308 RE11109 RE22047 RE29159 RE32794 RE37690 RE39040 RE54410 RE54747 RE61668 RE69484 RE73766 RE74196
Other clones	66175 74955 149507 163032 CK01.76C.F3 CK01.99C.F9 CK01.112D.A4 CK00465 EC25203 EC25237 EC28346 EC051616 EC053138 EK007602 EK059817 EK084421 EK206060 EK254501 EK255553 EK267354 ESG018b.E21.1_E05 RP004156955 RP004249760 RP004250092 RP004536576
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0029002 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 44787
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: miple2 CG18321 (Bayraktaroglu, 2000.8.7)
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_143739 NM_001274269 NM_001274270 NM_001274271 NM_001274272 RefSeq (Proteins) • NP_651996 NP_001261198 NP_001261199 NP_001261200 NP_001261201 DDBJ / EMBL / GenBank • AAF22851 AAF47369 AAL48676 AF215688 AGB93893 AGB93894 AGB93895 AGB93896 AY071054 BI171999 CZ469505 CZ477051 CZ477550 CZ477551 Entrez Gene - A searchable database of RefSeq genes. • 44787 UniProtKB/TrEMBL • Q8SZ83 Q9U3W4 Q9W0S4
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Pleiotrophin/Midkine heparin-binding growth factor, C-terminal domain (IPR020090) Pleiotrophin/Midkine heparin-binding growth factor, disulphide-rich domain (IPR020091) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RE13914
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0029002 DRSC - Results from RNAi screens. • FBgn0029002 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0029002 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG18321-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0029002 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 44787 modMine - Data generated by the modENCODE project. • FBgn0029002
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	CG18321 (Hollien and Weissman, 2006, Englund et al., 2006, Mosallanejad et al., 2010, Keleman et al., 2009.8.5, Haussmann et al., 2008) miple2 (Terry et al., 2006, Hollien and Weissman, 2006, Hollien and Weissman, 2006, Englund et al., 2006, Haussmann et al., 2008, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym	miple2 (Haussmann et al., 2008) Miple2 (Svensson et al., 2010)
Secondary FlyBase IDs
	FBgn0035123
References ( 27 )
Generate a list of	All references relating to this gene ( 27 )
List References by type	Research paper  ( 7 ) Supplementary material  ( 3 ) Personal communication to FlyBase  ( 11 ) FlyBase analysis  ( 2 ) Stock list  ( 1 ) DNA/RNA sequence record  ( 1 ) Website  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...