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Gene Dmel\COQ7

General Information
Symbol	Dmel\COQ7	Species	D. melanogaster
Name	COQ7	Annotation symbol	CG14437
Feature type	protein_coding_gene	FlyBase ID	FBgn0029502
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	6C13-6C13	Sequence location	X:6,665,258..6,667,072 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene COQ7 is referred to in FlyBase by the symbol Dmel\COQ7 (CG14437, FBgn0029502). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: transition metal ion binding; oxidoreductase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: oxidation-reduction process; ubiquinone biosynthetic process. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Ferritin-related; Ferritin/ribonucleotide reductase-like; Ubiquinone biosynthesis protein Coq7. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1635151_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of COQ7. Gene sequence location is X:6665258..6667072.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 6C13-6C13   Limits computationally determined from genome sequence between P{EP}Ctr1AEP1364&P{EP}EP1445 and P{EP}C3GEP1613
Experimentally Determined Cytological Location
Cytogenetic map Notes References 6E1-6E2     (Tricoire, 1999.12.30)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\COQ7 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.41 Gene model reviewed during 5.49
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) COQ7-RA FBtr0070963  NM_143710   899   219
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein COQ7-PA   FBpp0070924   24.1   219   6.96     NP_651967   AAF46199
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Ferritin-like superfamily (IPR009078) Ubiquinone biosynthesis protein Coq7 (IPR011566) Ferritin-related (IPR012347)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF46199   AJ252202 CAB64655   AJ252203 CAB64656   BI165503   BI364175   BI364452   BI365760   BI578392   BI581262   BI581426   BI619048   BI619540   BP560050   BP560051   BT031015   CO192739   CO338732   CZ482280   CZ486642   EC266245   EV578106
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9W3W4 Q9TVU0
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    117.75 Larval Midgut    114.6 Larval Hindgut    210.8 Larval Malpighian Tubules    193.5 Larval Fat Body    64.5 Larval Salivary Gland    168.1 Larval Trachea    146 Larval Carcass    123.7 Adult Head    195.3 Adult Eye    240.725 Adult Brain    375.3 Adult Thoracic-Abdominal Ganglion    334.1 Adult Crop    125.7 Adult Midgut    154.4 Adult Hindgut    346 Adult Malpighian Tubules    188.6 Adult Fat Body    73.2 Adult Salivary Gland    182 Adult Heart    152.05 Adult VirginFemale Spermatheca    47.3 Adult InseminatedFemale Spermatheca    52.7 Adult Ovary    167.6 Adult Testis    43.4 Adult Male Accessory Gland    135 Adult Carcass    234 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    117.75 Larval Midgut    114.6 Larval Hindgut    210.8 Larval Malpighian Tubules    193.5 Larval Fat Body    64.5 Larval Salivary Gland    168.1 Larval Trachea    146 Larval Carcass    123.7 Adult Head    195.3 Adult Eye    240.725 Adult Brain    375.3 Adult Thoracic-Abdominal Ganglion    334.1 Adult Crop    125.7 Adult Midgut    154.4 Adult Hindgut    346 Adult Malpighian Tubules    188.6 Adult Fat Body    73.2 Adult Salivary Gland    182 Adult Heart    152.05 Adult VirginFemale Spermatheca    47.3 Adult InseminatedFemale Spermatheca    52.7 Adult Ovary    167.6 Adult Testis    43.4 Adult Male Accessory Gland    135 Adult Carcass    234 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    117.75 Larval Midgut    114.6 Larval Hindgut    210.8 Larval Malpighian Tubules    193.5 Larval Fat Body    64.5 Larval Salivary Gland    168.1 Larval Trachea    146 Larval Carcass    123.7 Adult Head    195.3 Adult Eye    240.725 Adult Brain    375.3 Adult Thoracic-Abdominal Ganglion    334.1 Adult Crop    125.7 Adult Midgut    154.4 Adult Hindgut    346 Adult Malpighian Tubules    188.6 Adult Fat Body    73.2 Adult Salivary Gland    182 Adult Heart    152.05 Adult VirginFemale Spermatheca    47.3 Adult InseminatedFemale Spermatheca    52.7 Adult Ovary    167.6 Adult Testis    43.4 Adult Male Accessory Gland    135 Adult Carcass    234 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    117.75 Larval Midgut    114.6 Larval Hindgut    210.8 Larval Malpighian Tubules    193.5 Larval Fat Body    64.5 Larval Salivary Gland    168.1 Larval Trachea    146 Larval Carcass    123.7 Adult Head    195.3 Adult Eye    240.725 Adult Brain    375.3 Adult Thoracic-Abdominal Ganglion    334.1 Adult Crop    125.7 Adult Midgut    154.4 Adult Hindgut    346 Adult Malpighian Tubules    188.6 Adult Fat Body    73.2 Adult Salivary Gland    182 Adult Heart    152.05 Adult VirginFemale Spermatheca    47.3 Adult InseminatedFemale Spermatheca    52.7 Adult Ovary    167.6 Adult Testis    43.4 Adult Male Accessory Gland    135 Adult Carcass    234 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    117.75 Larval Midgut    114.6 Larval Hindgut    210.8 Larval Malpighian Tubules    193.5 Larval Fat Body    64.5 Larval Salivary Gland    168.1 Larval Trachea    146 Larval Carcass    123.7 Adult Head    195.3 Adult Eye    240.725 Adult Brain    375.3 Adult Thoracic-Abdominal Ganglion    334.1 Adult Crop    125.7 Adult Midgut    154.4 Adult Hindgut    346 Adult Malpighian Tubules    188.6 Adult Fat Body    73.2 Adult Salivary Gland    182 Adult Heart    152.05 Adult VirginFemale Spermatheca    47.3 Adult InseminatedFemale Spermatheca    52.7 Adult Ovary    167.6 Adult Testis    43.4 Adult Male Accessory Gland    135 Adult Carcass    234 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    117.75 Larval Midgut    114.6 Larval Hindgut    210.8 Larval Malpighian Tubules    193.5 Larval Fat Body    64.5 Larval Salivary Gland    168.1 Larval Trachea    146 Larval Carcass    123.7 Adult Head    195.3 Adult Eye    240.725 Adult Brain    375.3 Adult Thoracic-Abdominal Ganglion    334.1 Adult Crop    125.7 Adult Midgut    154.4 Adult Hindgut    346 Adult Malpighian Tubules    188.6 Adult Fat Body    73.2 Adult Salivary Gland    182 Adult Heart    152.05 Adult VirginFemale Spermatheca    47.3 Adult InseminatedFemale Spermatheca    52.7 Adult Ovary    167.6 Adult Testis    43.4 Adult Male Accessory Gland    135 Adult Carcass    234 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    117.75 Larval Midgut    114.6 Larval Hindgut    210.8 Larval Malpighian Tubules    193.5 Larval Fat Body    64.5 Larval Salivary Gland    168.1 Larval Trachea    146 Larval Carcass    123.7 Adult Head    195.3 Adult Eye    240.725 Adult Brain    375.3 Adult Thoracic-Abdominal Ganglion    334.1 Adult Crop    125.7 Adult Midgut    154.4 Adult Hindgut    346 Adult Malpighian Tubules    188.6 Adult Fat Body    73.2 Adult Salivary Gland    182 Adult Heart    152.05 Adult VirginFemale Spermatheca    47.3 Adult InseminatedFemale Spermatheca    52.7 Adult Ovary    167.6 Adult Testis    43.4 Adult Male Accessory Gland    135 Adult Carcass    234 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    117.75 Larval Midgut    114.6 Larval Hindgut    210.8 Larval Malpighian Tubules    193.5 Larval Fat Body    64.5 Larval Salivary Gland    168.1 Larval Trachea    146 Larval Carcass    123.7 Adult Head    195.3 Adult Eye    240.725 Adult Brain    375.3 Adult Thoracic-Abdominal Ganglion    334.1 Adult Crop    125.7 Adult Midgut    154.4 Adult Hindgut    346 Adult Malpighian Tubules    188.6 Adult Fat Body    73.2 Adult Salivary Gland    182 Adult Heart    152.05 Adult VirginFemale Spermatheca    47.3 Adult InseminatedFemale Spermatheca    52.7 Adult Ovary    167.6 Adult Testis    43.4 Adult Male Accessory Gland    135 Adult Carcass    234 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    195.3   NA  Eye    240.725   NA  Brain    375.3   117.75  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    334.1   NA  Crop    125.7   114.6  Midgut    154.4   210.8  Hindgut    346   193.5  Malpighian Tubules    188.6   64.5  Fat Body    73.2   168.1  Salivary Gland    182   NA  Heart    152.05   146  Trachea    NA   NA  VirginFemale Spermatheca    47.3   NA  InseminatedFemale Spermatheca    52.7   NA  Ovary    167.6   NA  Testis    43.4   NA  Male Accessory Gland    135   123.7  Carcass    234 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    16 central nervous system, pupae P8    13 head, virgin 1-day female    20 head, virgin 4-day female    28 head, virgin 20-day female    27 head, mated 1-day female    21 head, mated 4-day female    30 head, mated 20-day female    21 head, mated 1-day male    37 head, mated 4-day male    36 head, mated 20-day male    58 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    28 digestive system, 1-day adult    33 digestive system, 4-day adult    24 digestive system, 20-day adult    31 fat body, larvae L3 wandering    5 fat body, white prepupae    12 fat body, pupae P8    8 carcass, larvae L3 wandering    17 carcass, 1-day adult    28 carcass, 4-day adult    43 carcass, 20-day adult    48 ovary, virgin 4-day female    45 ovary, mated 4-day female    42 testis, mated 4-day male    16 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    16 central nervous system, pupae P8    13 head, virgin 1-day female    20 head, virgin 4-day female  (28) head, virgin 20-day female  (27) head, mated 1-day female    21 head, mated 4-day female  (30) head, mated 20-day female    21 head, mated 1-day male  (37) head, mated 4-day male  (36) head, mated 20-day male  (58) salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    3 digestive system, larvae L3 wandering  (28) digestive system, 1-day adult  (33) digestive system, 4-day adult    24 digestive system, 20-day adult  (31) fat body, larvae L3 wandering    5 fat body, white prepupae    12 fat body, pupae P8    8 carcass, larvae L3 wandering    17 carcass, 1-day adult  (28) carcass, 4-day adult  (43) carcass, 20-day adult  (48) ovary, virgin 4-day female  (45) ovary, mated 4-day female  (42) testis, mated 4-day male    16 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    16 central nervous system, pupae P8    13 head, virgin 1-day female    20 head, virgin 4-day female    28 head, virgin 20-day female    27 head, mated 1-day female    21 head, mated 4-day female    30 head, mated 20-day female    21 head, mated 1-day male    37 head, mated 4-day male    36 head, mated 20-day male    58 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    28 digestive system, 1-day adult    33 digestive system, 4-day adult    24 digestive system, 20-day adult    31 fat body, larvae L3 wandering    5 fat body, white prepupae    12 fat body, pupae P8    8 carcass, larvae L3 wandering    17 carcass, 1-day adult    28 carcass, 4-day adult    43 carcass, 20-day adult    48 ovary, virgin 4-day female    45 ovary, mated 4-day female    42 testis, mated 4-day male    16 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    16 central nervous system, pupae P8    13 head, virgin 1-day female    20 head, virgin 4-day female    28 head, virgin 20-day female    27 head, mated 1-day female    21 head, mated 4-day female    30 head, mated 20-day female    21 head, mated 1-day male    37 head, mated 4-day male    36 head, mated 20-day male    58 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    28 digestive system, 1-day adult    33 digestive system, 4-day adult    24 digestive system, 20-day adult    31 fat body, larvae L3 wandering    5 fat body, white prepupae    12 fat body, pupae P8    8 carcass, larvae L3 wandering    17 carcass, 1-day adult    28 carcass, 4-day adult    43 carcass, 20-day adult    48 ovary, virgin 4-day female    45 ovary, mated 4-day female    42 testis, mated 4-day male    16 accessory gland, mated 4-day male    18 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    16 central nervous system, pupae P8    13 head, virgin 1-day female    20 head, virgin 4-day female    28 head, virgin 20-day female    27 head, mated 1-day female    21 head, mated 4-day female    30 head, mated 20-day female    21 head, mated 1-day male    37 head, mated 4-day male    36 head, mated 20-day male    58 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    28 digestive system, 1-day adult    33 digestive system, 4-day adult    24 digestive system, 20-day adult    31 fat body, larvae L3 wandering    5 fat body, white prepupae    12 fat body, pupae P8    8 carcass, larvae L3 wandering    17 carcass, 1-day adult    28 carcass, 4-day adult    43 carcass, 20-day adult    48 ovary, virgin 4-day female    45 ovary, mated 4-day female    42 testis, mated 4-day male    16 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    16 central nervous system, pupae P8    13 head, virgin 1-day female    20 head, virgin 4-day female  28 head, virgin 20-day female  27 head, mated 1-day female    21 head, mated 4-day female  30 head, mated 20-day female    21 head, mated 1-day male  (37) head, mated 4-day male  (36) head, mated 20-day male  (58) salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    3 digestive system, larvae L3 wandering  28 digestive system, 1-day adult  (33) digestive system, 4-day adult    24 digestive system, 20-day adult  31 fat body, larvae L3 wandering    5 fat body, white prepupae    12 fat body, pupae P8    8 carcass, larvae L3 wandering    17 carcass, 1-day adult  28 carcass, 4-day adult  (43) carcass, 20-day adult  (48) ovary, virgin 4-day female  (45) ovary, mated 4-day female  (42) testis, mated 4-day male    16 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    16 central nervous system, pupae P8    13 head, virgin 1-day female    20 head, virgin 4-day female    28 head, virgin 20-day female    27 head, mated 1-day female    21 head, mated 4-day female    30 head, mated 20-day female    21 head, mated 1-day male    37 head, mated 4-day male    36 head, mated 20-day male    58 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    28 digestive system, 1-day adult    33 digestive system, 4-day adult    24 digestive system, 20-day adult    31 fat body, larvae L3 wandering    5 fat body, white prepupae    12 fat body, pupae P8    8 carcass, larvae L3 wandering    17 carcass, 1-day adult    28 carcass, 4-day adult    43 carcass, 20-day adult    48 ovary, virgin 4-day female    45 ovary, mated 4-day female    42 testis, mated 4-day male    16 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    16 central nervous system, pupae P8    13 head, virgin 1-day female    20 head, virgin 4-day female    28 head, virgin 20-day female    27 head, mated 1-day female    21 head, mated 4-day female    30 head, mated 20-day female    21 head, mated 1-day male    37 head, mated 4-day male    36 head, mated 20-day male    58 salivary gland, larvae L3 wandering    4 salivary gland, white prepupae    3 digestive system, larvae L3 wandering    28 digestive system, 1-day adult    33 digestive system, 4-day adult    24 digestive system, 20-day adult    31 fat body, larvae L3 wandering    5 fat body, white prepupae    12 fat body, pupae P8    8 carcass, larvae L3 wandering    17 carcass, 1-day adult    28 carcass, 4-day adult    43 carcass, 20-day adult    48 ovary, virgin 4-day female    45 ovary, mated 4-day female    42 testis, mated 4-day male    16 accessory gland, mated 4-day male    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    54 embryo 02-04hr    14 embryo 04-06hr    25 embryo 06-08hr    21 embryo 08-10hr    22 embryo 10-12hr    24 embryo 12-14hr    16 embryo 14-16hr    23 embryo 16-18hr    23 embryo 18-20hr    21 embryo 20-22hr    17 embryo 22-24hr    17 larva L1    34 larva L2    38 larva L3 12hr old    31 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    25 larva L3 puffstage 7-9    24 white prepupae new    20 white prepupae 12hr    18 white prepupae 24hr    19 pupae 2d postWPP    25 pupae 3d postWPP    29 pupae 4d postWPP    36 adult male 01day    42 adult male 05day    55 adult male 30day    67 adult female 01day    52 adult female 05day    50 adult female 30day    51 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (54) embryo 02-04hr    14 embryo 04-06hr    25 embryo 06-08hr    21 embryo 08-10hr    22 embryo 10-12hr    24 embryo 12-14hr    16 embryo 14-16hr    23 embryo 16-18hr    23 embryo 18-20hr    21 embryo 20-22hr    17 embryo 22-24hr    17 larva L1  (34) larva L2  (38) larva L3 12hr old  (31) larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    25 larva L3 puffstage 7-9    24 white prepupae new    20 white prepupae 12hr    18 white prepupae 24hr    19 pupae 2d postWPP    25 pupae 3d postWPP  (29) pupae 4d postWPP  (36) adult male 01day  (42) adult male 05day  (55) adult male 30day  (67) adult female 01day  (52) adult female 05day  (50) adult female 30day  (51) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    54 embryo 02-04hr    14 embryo 04-06hr    25 embryo 06-08hr    21 embryo 08-10hr    22 embryo 10-12hr    24 embryo 12-14hr    16 embryo 14-16hr    23 embryo 16-18hr    23 embryo 18-20hr    21 embryo 20-22hr    17 embryo 22-24hr    17 larva L1    34 larva L2    38 larva L3 12hr old    31 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    25 larva L3 puffstage 7-9    24 white prepupae new    20 white prepupae 12hr    18 white prepupae 24hr    19 pupae 2d postWPP    25 pupae 3d postWPP    29 pupae 4d postWPP    36 adult male 01day    42 adult male 05day    55 adult male 30day    67 adult female 01day    52 adult female 05day    50 adult female 30day    51 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    54 embryo 02-04hr    14 embryo 04-06hr    25 embryo 06-08hr    21 embryo 08-10hr    22 embryo 10-12hr    24 embryo 12-14hr    16 embryo 14-16hr    23 embryo 16-18hr    23 embryo 18-20hr    21 embryo 20-22hr    17 embryo 22-24hr    17 larva L1    34 larva L2    38 larva L3 12hr old    31 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    25 larva L3 puffstage 7-9    24 white prepupae new    20 white prepupae 12hr    18 white prepupae 24hr    19 pupae 2d postWPP    25 pupae 3d postWPP    29 pupae 4d postWPP    36 adult male 01day    42 adult male 05day    55 adult male 30day    67 adult female 01day    52 adult female 05day    50 adult female 30day    51 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    54 embryo 02-04hr    14 embryo 04-06hr    25 embryo 06-08hr    21 embryo 08-10hr    22 embryo 10-12hr    24 embryo 12-14hr    16 embryo 14-16hr    23 embryo 16-18hr    23 embryo 18-20hr    21 embryo 20-22hr    17 embryo 22-24hr    17 larva L1    34 larva L2    38 larva L3 12hr old    31 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    25 larva L3 puffstage 7-9    24 white prepupae new    20 white prepupae 12hr    18 white prepupae 24hr    19 pupae 2d postWPP    25 pupae 3d postWPP    29 pupae 4d postWPP    36 adult male 01day    42 adult male 05day    55 adult male 30day    67 adult female 01day    52 adult female 05day    50 adult female 30day    51 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (54) embryo 02-04hr    14 embryo 04-06hr    25 embryo 06-08hr    21 embryo 08-10hr    22 embryo 10-12hr    24 embryo 12-14hr    16 embryo 14-16hr    23 embryo 16-18hr    23 embryo 18-20hr    21 embryo 20-22hr    17 embryo 22-24hr    17 larva L1  (34) larva L2  (38) larva L3 12hr old  31 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    25 larva L3 puffstage 7-9    24 white prepupae new    20 white prepupae 12hr    18 white prepupae 24hr    19 pupae 2d postWPP    25 pupae 3d postWPP  29 pupae 4d postWPP  (36) adult male 01day  (42) adult male 05day  (55) adult male 30day  (67) adult female 01day  (52) adult female 05day  (50) adult female 30day  (51) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    54 embryo 02-04hr    14 embryo 04-06hr    25 embryo 06-08hr    21 embryo 08-10hr    22 embryo 10-12hr    24 embryo 12-14hr    16 embryo 14-16hr    23 embryo 16-18hr    23 embryo 18-20hr    21 embryo 20-22hr    17 embryo 22-24hr    17 larva L1    34 larva L2    38 larva L3 12hr old    31 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    25 larva L3 puffstage 7-9    24 white prepupae new    20 white prepupae 12hr    18 white prepupae 24hr    19 pupae 2d postWPP    25 pupae 3d postWPP    29 pupae 4d postWPP    36 adult male 01day    42 adult male 05day    55 adult male 30day    67 adult female 01day    52 adult female 05day    50 adult female 30day    51 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    54 embryo 02-04hr    14 embryo 04-06hr    25 embryo 06-08hr    21 embryo 08-10hr    22 embryo 10-12hr    24 embryo 12-14hr    16 embryo 14-16hr    23 embryo 16-18hr    23 embryo 18-20hr    21 embryo 20-22hr    17 embryo 22-24hr    17 larva L1    34 larva L2    38 larva L3 12hr old    31 larva L3 puffstage 1-2    25 larva L3 puffstage 3-6    25 larva L3 puffstage 7-9    24 white prepupae new    20 white prepupae 12hr    18 white prepupae 24hr    19 pupae 2d postWPP    25 pupae 3d postWPP    29 pupae 4d postWPP    36 adult male 01day    42 adult male 05day    55 adult male 30day    67 adult female 01day    52 adult female 05day    50 adult female 30day    51 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    66 Schneider line 2 Sg4    33 embryonic 1182-4H    68 embryonic GM2    40 embryonic Kc167    23 embryonic S1    57 embryonic S3    27 leg disc CME L1    42 wing disc CME-W2    30 wing disc ML-DmD8    32 wing disc ML-DmD9    72 wing disc ML-DmD16-c3    49 wing disc ML-DmD21    79 wing disc ML-DmD32    53 haltere disc ML-DmD17-c3    66 eye-antennal disc ML-DmD11    66 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    34 CNS ML-DmBG1-c1    56 CNS ML-DmBG2-c2    40 tumorous blood cells mbn2    110 ovary fGS/OSS    56 ovary OSC    36 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (66) Schneider line 2 Sg4  (33) embryonic 1182-4H  (68) embryonic GM2  (40) embryonic Kc167    23 embryonic S1  (57) embryonic S3  (27) leg disc CME L1  (42) wing disc CME-W2  (30) wing disc ML-DmD8  (32) wing disc ML-DmD9  (72) wing disc ML-DmD16-c3  (49) wing disc ML-DmD21  (79) wing disc ML-DmD32  (53) haltere disc ML-DmD17-c3  (66) eye-antennal disc ML-DmD11  (66) antennal disc ML-DmD20-c5  (44) mixed discs ML-DmD4-c1  (34) CNS ML-DmBG1-c1  (56) CNS ML-DmBG2-c2  (40) tumorous blood cells mbn2  (110) ovary fGS/OSS  (56) ovary OSC  (36) ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    66 Schneider line 2 Sg4    33 embryonic 1182-4H    68 embryonic GM2    40 embryonic Kc167    23 embryonic S1    57 embryonic S3    27 leg disc CME L1    42 wing disc CME-W2    30 wing disc ML-DmD8    32 wing disc ML-DmD9    72 wing disc ML-DmD16-c3    49 wing disc ML-DmD21    79 wing disc ML-DmD32    53 haltere disc ML-DmD17-c3    66 eye-antennal disc ML-DmD11    66 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    34 CNS ML-DmBG1-c1    56 CNS ML-DmBG2-c2    40 tumorous blood cells mbn2  (110) ovary fGS/OSS    56 ovary OSC    36 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    66 Schneider line 2 Sg4    33 embryonic 1182-4H    68 embryonic GM2    40 embryonic Kc167    23 embryonic S1    57 embryonic S3    27 leg disc CME L1    42 wing disc CME-W2    30 wing disc ML-DmD8    32 wing disc ML-DmD9    72 wing disc ML-DmD16-c3    49 wing disc ML-DmD21    79 wing disc ML-DmD32    53 haltere disc ML-DmD17-c3    66 eye-antennal disc ML-DmD11    66 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    34 CNS ML-DmBG1-c1    56 CNS ML-DmBG2-c2    40 tumorous blood cells mbn2    110 ovary fGS/OSS    56 ovary OSC    36 ovary OSS    17 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    66 Schneider line 2 Sg4    33 embryonic 1182-4H    68 embryonic GM2    40 embryonic Kc167    23 embryonic S1    57 embryonic S3    27 leg disc CME L1    42 wing disc CME-W2    30 wing disc ML-DmD8    32 wing disc ML-DmD9    72 wing disc ML-DmD16-c3    49 wing disc ML-DmD21    79 wing disc ML-DmD32    53 haltere disc ML-DmD17-c3    66 eye-antennal disc ML-DmD11    66 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    34 CNS ML-DmBG1-c1    56 CNS ML-DmBG2-c2    40 tumorous blood cells mbn2    110 ovary fGS/OSS    56 ovary OSC    36 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (66) Schneider line 2 Sg4  (33) embryonic 1182-4H  (68) embryonic GM2  (40) embryonic Kc167    23 embryonic S1  (57) embryonic S3  27 leg disc CME L1  (42) wing disc CME-W2  30 wing disc ML-DmD8  32 wing disc ML-DmD9  (72) wing disc ML-DmD16-c3  (49) wing disc ML-DmD21  (79) wing disc ML-DmD32  (53) haltere disc ML-DmD17-c3  (66) eye-antennal disc ML-DmD11  (66) antennal disc ML-DmD20-c5  (44) mixed discs ML-DmD4-c1  (34) CNS ML-DmBG1-c1  (56) CNS ML-DmBG2-c2  (40) tumorous blood cells mbn2  (110) ovary fGS/OSS  (56) ovary OSC  (36) ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    66 Schneider line 2 Sg4    33 embryonic 1182-4H    68 embryonic GM2    40 embryonic Kc167    23 embryonic S1    57 embryonic S3    27 leg disc CME L1    42 wing disc CME-W2    30 wing disc ML-DmD8    32 wing disc ML-DmD9    72 wing disc ML-DmD16-c3    49 wing disc ML-DmD21    79 wing disc ML-DmD32    53 haltere disc ML-DmD17-c3    66 eye-antennal disc ML-DmD11    66 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    34 CNS ML-DmBG1-c1    56 CNS ML-DmBG2-c2    40 tumorous blood cells mbn2  110 ovary fGS/OSS    56 ovary OSC    36 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    66 Schneider line 2 Sg4    33 embryonic 1182-4H    68 embryonic GM2    40 embryonic Kc167    23 embryonic S1    57 embryonic S3    27 leg disc CME L1    42 wing disc CME-W2    30 wing disc ML-DmD8    32 wing disc ML-DmD9    72 wing disc ML-DmD16-c3    49 wing disc ML-DmD21    79 wing disc ML-DmD32    53 haltere disc ML-DmD17-c3    66 eye-antennal disc ML-DmD11    66 antennal disc ML-DmD20-c5    44 mixed discs ML-DmD4-c1    34 CNS ML-DmBG1-c1    56 CNS ML-DmBG2-c2    40 tumorous blood cells mbn2    110 ovary fGS/OSS    56 ovary OSC    36 ovary OSS    17 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    15 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    35 Cadmium 100 mM 48 hrs, 4-day adult    49 Copper 0.5 mM 12 hrs, larvae L3    13 Copper 15 mM 48 hrs, 4-day adult    45 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    35 Ethanol 2.5% 3 hrs, larvae L3    62 Ethanol 5% 3 hrs, larvae L3    31 Ethanol 10% 3 hrs, larvae L3    27 Caffeine 1.5 mg/ml 4 hrs, larvae L3    30 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    52 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    47 Paraquat 10 mM 48 hrs, 4-day adult    61 Rotenone 2 μg 12 hrs, larvae L3    25 Rotenone 8 μg 12 hrs, larvae L3    34 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    15 heat shock, 4-day adult  (34) Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult  (35) Cadmium 100 mM 48 hrs, 4-day adult  (49) Copper 0.5 mM 12 hrs, larvae L3    13 Copper 15 mM 48 hrs, 4-day adult  (45) Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult  (35) Ethanol 2.5% 3 hrs, larvae L3  (62) Ethanol 5% 3 hrs, larvae L3  (31) Ethanol 10% 3 hrs, larvae L3  (27) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (30) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (52) Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult  (47) Paraquat 10 mM 48 hrs, 4-day adult  (61) Rotenone 2 μg 12 hrs, larvae L3    25 Rotenone 8 μg 12 hrs, larvae L3  (34) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    15 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    35 Cadmium 100 mM 48 hrs, 4-day adult    49 Copper 0.5 mM 12 hrs, larvae L3    13 Copper 15 mM 48 hrs, 4-day adult    45 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    35 Ethanol 2.5% 3 hrs, larvae L3    62 Ethanol 5% 3 hrs, larvae L3    31 Ethanol 10% 3 hrs, larvae L3    27 Caffeine 1.5 mg/ml 4 hrs, larvae L3    30 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    52 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    47 Paraquat 10 mM 48 hrs, 4-day adult    61 Rotenone 2 μg 12 hrs, larvae L3    25 Rotenone 8 μg 12 hrs, larvae L3    34 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    15 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    35 Cadmium 100 mM 48 hrs, 4-day adult    49 Copper 0.5 mM 12 hrs, larvae L3    13 Copper 15 mM 48 hrs, 4-day adult    45 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    35 Ethanol 2.5% 3 hrs, larvae L3    62 Ethanol 5% 3 hrs, larvae L3    31 Ethanol 10% 3 hrs, larvae L3    27 Caffeine 1.5 mg/ml 4 hrs, larvae L3    30 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    52 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    47 Paraquat 10 mM 48 hrs, 4-day adult    61 Rotenone 2 μg 12 hrs, larvae L3    25 Rotenone 8 μg 12 hrs, larvae L3    34 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    15 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    35 Cadmium 100 mM 48 hrs, 4-day adult    49 Copper 0.5 mM 12 hrs, larvae L3    13 Copper 15 mM 48 hrs, 4-day adult    45 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    35 Ethanol 2.5% 3 hrs, larvae L3    62 Ethanol 5% 3 hrs, larvae L3    31 Ethanol 10% 3 hrs, larvae L3    27 Caffeine 1.5 mg/ml 4 hrs, larvae L3    30 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    52 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    47 Paraquat 10 mM 48 hrs, 4-day adult    61 Rotenone 2 μg 12 hrs, larvae L3    25 Rotenone 8 μg 12 hrs, larvae L3    34 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    15 heat shock, 4-day adult  (34) Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult  (35) Cadmium 100 mM 48 hrs, 4-day adult  (49) Copper 0.5 mM 12 hrs, larvae L3    13 Copper 15 mM 48 hrs, 4-day adult  (45) Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult  (35) Ethanol 2.5% 3 hrs, larvae L3  (62) Ethanol 5% 3 hrs, larvae L3  31 Ethanol 10% 3 hrs, larvae L3  27 Caffeine 1.5 mg/ml 4 hrs, larvae L3  30 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (52) Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult  (47) Paraquat 10 mM 48 hrs, 4-day adult  (61) Rotenone 2 μg 12 hrs, larvae L3    25 Rotenone 8 μg 12 hrs, larvae L3  (34) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    15 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    35 Cadmium 100 mM 48 hrs, 4-day adult    49 Copper 0.5 mM 12 hrs, larvae L3    13 Copper 15 mM 48 hrs, 4-day adult    45 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    35 Ethanol 2.5% 3 hrs, larvae L3    62 Ethanol 5% 3 hrs, larvae L3    31 Ethanol 10% 3 hrs, larvae L3    27 Caffeine 1.5 mg/ml 4 hrs, larvae L3    30 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    52 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    47 Paraquat 10 mM 48 hrs, 4-day adult    61 Rotenone 2 μg 12 hrs, larvae L3    25 Rotenone 8 μg 12 hrs, larvae L3    34 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    25 cold shock, 4-day adult    15 heat shock, 4-day adult    34 Cadmium 50 mM 6 hrs, larvae L3    20 Cadmium 50 mM 12 hrs, larvae L3    20 Cadmium 50 mM 48 hrs, 4-day adult    35 Cadmium 100 mM 48 hrs, 4-day adult    49 Copper 0.5 mM 12 hrs, larvae L3    13 Copper 15 mM 48 hrs, 4-day adult    45 Zinc 5 mM 12 hrs, larvae L3    12 Zinc 4.5 mM 48 hrs, 4-day adult    35 Ethanol 2.5% 3 hrs, larvae L3    62 Ethanol 5% 3 hrs, larvae L3    31 Ethanol 10% 3 hrs, larvae L3    27 Caffeine 1.5 mg/ml 4 hrs, larvae L3    30 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    52 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    47 Paraquat 10 mM 48 hrs, 4-day adult    61 Rotenone 2 μg 12 hrs, larvae L3    25 Rotenone 8 μg 12 hrs, larvae L3    34 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_26 mE1_20_mRNA_expression_cluster_09
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0029502 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14437-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 COQ7GD8325 Other Phenotypes Allele developmental rate defective | RU486 conditional, with Scer\GAL4da.Switch.PT COQ7GD8325 short lived | female | RU486 conditional, with Scer\GAL4da.Switch.PT COQ7GD8325 Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of COQ7 Class Mutagen Stocks Known lesion COQ7e04529 piggyBac transposase 1 -- COQ7f04093 piggyBac transposase 1 -- COQ7NP3213 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of COQ7 Class Mutagen Stocks Known lesion COQ7GD8325 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes COQ7KK108608 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes COQ7NIG.14437R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(1)2.5 (Gorfinkiel et al., 2005)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD8325} NA P{KK108608} NA P{NIG.14437R} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{RB}COQ7e04529 NA PBac{WH}COQ7f04093 NA insertion of enhancer trap binary system P{GawB}COQ7NP3213 No
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
oxidoreductase activity inferred from electronic annotation with InterPro:IPR009078 (FlyBase Curators et al., 2004-) transition metal ion binding inferred from electronic annotation with InterPro:IPR009078 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
oxidation-reduction process inferred from electronic annotation with InterPro:IPR009078, InterPro:IPR011566 (FlyBase Curators et al., 2004-) ubiquinone biosynthetic process inferred from electronic annotation with InterPro:IPR011566 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
mitochondrion inferred from sequence or structural similarity with mouse Coq7 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions COQ7 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 68770 DroID - A comprehensive database of gene and protein interactions. • FBgn0029502 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 44007
Orthologs
OrthoDB Orthologs (40) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6FN542 Dipteran inclusive ortholog search EOG6VQ9ZB Insect inclusive ortholog search EOG6CZ9C4 Arthropod inclusive ortholog search EOG61JWVD Metazoa inclusive ortholog search EOG6ZKXG5
Orthologs in Drosophila Species (EOG6FN542)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\COQ7     Drosophila simulans   Dsim\GD16815 Y   Drosophila sechellia   Dsec\GM12529 Y   Drosophila erecta   Dere\GG19611 Y   Drosophila yakuba   Dyak\GE16772 Y   Drosophila ananassae   Dana\GF19758 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA12984 Y   Drosophila persimilis   Dper\GL26752 Y   Drosophila willistoni   Dwil\GK25105 Y   Drosophila virilis   Dvir\GJ16885 Y   Drosophila mojavensis   Dmoj\GI21648 Y   Drosophila grimshawi   Dgri\GH24447 Y
Orthologs in non-Drosophila Dipterans (EOG6VQ9ZB)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL011379   Anopheles gambiae Malaria mosquito  Agam\AGAP000118   Anopheles gambiae Malaria mosquito  Agam\AGAP006572   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ003762
Orthologs in non-Dipteran Insects (EOG6CZ9C4)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\Coq7   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG006037   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH23645   Atta cephalotes Leafcutter ant  Acep\ACEP26976   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL15818   Linepithema humile Argentine ant  Lhum\LH23403   Pogonomyrmex barbatus Red harvester ant  Pbar\PB14642   Solenopsis invicta Red fire ant  Sinv\SINV24549   Acyrthosiphon pisum Pea aphid  Apim\ACYPI003157   Bombyx mori Silkmoth  Bmor\BGIBMGA005794   Pediculus humanus Human body louse  Phum\PHUM477240   Tribolium castaneum Red flour beetle  Tcas\TC014699
Orthologs in non-Insect Arthropods (EOG61JWVD)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_230290   Ixodes scapularis Deer tick  Isca\ISCW024637   Ixodes scapularis Deer tick  Isca\ISCW022462
Orthologs in non-Arthropod Metazoa (EOG6ZKXG5)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\clk-1   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_018829gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028555gn   Danio rerio Zebrafish  Drer\zgc:158731   Xenopus tropicalis Western clawed frog  Xtro\coq7   Gallus gallus Domestic chicken  Ggal\COQ7   Mus musculus House mouse  Mmus\Coq7   Rattus norvegicus Norway rat  Rnor\Coq7   Homo sapiens Human  Hsap\COQ7
Human Orthologs (1)
Gene OMIM HGNC Hsap\COQ7
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD16815 Drosophila sechellia Dsec\GM12529 Drosophila erecta Dere\GG19611 Drosophila yakuba Dyak\GE16772 Drosophila ananassae Dana\GF19758 Drosophila pseudoobscura pseudoobscura Dpse\GA12984 Drosophila persimilis Dper\GL26752 Drosophila willistoni Dwil\GK25105 Drosophila virilis Dvir\GJ16885 Drosophila mojavensis Dmoj\GI21648 Drosophila grimshawi Dgri\GH24447
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Harvard	- PBac{RB}COQ7e04529 - PBac{WH}COQ7f04093
Kyoto	104416 y* w* P{GawB}COQ7NP3213 / FM7c
VDRC	v106100 P{KK108608}VIE-260B v17602 w1118; P{GD8325}v17602 v17603 w1118; P{GD8325}v17603/TM3
Genomic Clones ( 1 )
	BACR48O24 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 15 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE45235
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE05421 RE49238 RE49558 RE51138 RE72259 RH18631 RH18838 RH50012 RH50591
Other clones	572913 Dmel_dig_007727_0635_2076 EC34385 EN17510 FGM324D04
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0029502 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 44007
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: COQ7 CG14437 (Bayraktaroglu, 2000.8.7)
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_143710 RefSeq (Proteins) • NP_651967 DDBJ / EMBL / GenBank • AAF46199 AJ252202 AJ252203 BI619048 CAB64655 CAB64656 CZ482280 CZ486642 Entrez Gene - A searchable database of RefSeq genes. • 44007 UniProtKB/TrEMBL • Q9TVU0 Q9W3W4
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Ferritin-like superfamily (IPR009078) Ubiquinone biosynthesis protein Coq7 (IPR011566) Ferritin-related (IPR012347)
Linkouts
	BioGRID - A database of protein and genetic interactions • 68770 DroID - A comprehensive database of gene and protein interactions. • FBgn0029502 DRSC - Results from RNAi screens. • FBgn0029502 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0029502 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG14437-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0029502 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 44007 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 44007 modMine - Data generated by the modENCODE project. • FBgn0029502
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	CG14437 (Keleman et al., 2009.8.5) COQ7 (Rera et al., 2010, Japanese National Institute of Genetics, 2012.5.21) Dclk1 (Tricoire et al., 2000)
Name Synonym	COQ7
Secondary FlyBase IDs
	FBgn0029900
References ( 21 )
Generate a list of	All references relating to this gene ( 21 )
List References by type	Research paper  ( 3 ) Supplementary material  ( 4 ) Personal communication to FlyBase  ( 7 ) Abstract  ( 1 ) FlyBase analysis  ( 2 ) Stock list  ( 1 ) DNA/RNA sequence record  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...