Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CHES-1-like using the Feature Mapper tool.
Ches-1-like transcript is first expressed at embryonic stage 8 occurs at stage 8, in the embryonic hemocyte primordium; this expression ends with the delamination and migration of embryonic hemocytes. Ches-1-like transcript is expressed in th salivary gland placodes from embryonic stage 10 though the invagination of the salivary gland primordia during stage 11-12. Expression is observed at stage 11 in the dorsal somatic mesoderm, continuing through stage 12 in a segmentally repeated pattern in the dorsoventral somatic muscle primordium. This pattern declines between stage 13 and 14, when transcript expression appears in the anterior embryonic hindgut.
GBrowse - Visual display of RNA-Seq signalsView Dmel\CHES-1-like in GBrowse 2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
CHES-1-like is required during asymmetric cell division for the derivation of two distinct cardial cells types (svp-expressing cardial cell and svp-expressing pericardial cell) from their mutual precursor. It is also required in symmetric cell divisions that produce the tin-expressing cardial cells. CHES-1-like controls the division of the cardiac progenitors by regulating the activity of polo.
S2 cells treated with dsRNA generated against this gene show reduced phagocytosis of Candida albicans compared to untreated cells.