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Gene Dmel\CG6067

General Information
Symbol	Dmel\CG6067	Species	D. melanogaster
Name		Annotation symbol	CG6067
Feature type	protein_coding_gene	FlyBase ID	FBgn0029828
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	5D1-5D1	Sequence location	X:5,849,663..5,852,317 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG6067 (FBgn0029828). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: serine-type endopeptidase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: proteolysis. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Peptidase S1/S6, chymotrypsin/Hap; Peptidase cysteine/serine, trypsin-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed in adults stages of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult midgut, adult heart, adult fat body, adult spermathecae, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval midgut, larval fat body. Comments on Affy2 ProbeSet: ProbeSet 1623298_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG6067. Gene sequence location is X:5849663..5852317.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA18399 BKN26327
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 5D1-5D1   Limits computationally determined from genome sequence between P{EP}Act5CEP1604&P{EP}EP444 and P{EP}EP1457EP1457&P{EP}CG5928EP1083
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG6067 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG6067-RA FBtr0070864  NM_132055   1408   307
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG6067-PA   FBpp0070829   34.0   307   7.70     NP_572283   AAF46106
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Peptidase S1/S6, chymotrypsin/Hap (IPR001254) Peptidase cysteine/serine, trypsin-like (IPR009003)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF46106   AY118421 AAM48450   BI367480   BI370795   BT120045   EC051145   EC053654   EC053655   EC055584   EC055956   GH779154   GH780790   GH794455   GH811854   GH813963   GH818713   GH822762   GH835226   GH836998   GH844700   GH846845   GH848078   GH851013   GH858964   GH863842   GH871318   GH876291   GH892980   GH904860   GH907531   GH909677   GH922136   GH929548   GH932752   GH933922
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8MT25 Q9W452
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0029828    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0029828 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed in adults stages of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0029828 expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    13 embryo 04-06hr    12 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    16 embryo 16-18hr    103 embryo 18-20hr    371 embryo 20-22hr    350 embryo 22-24hr    450 larva L1    154 larva L2    187 larva L3 12hr old    338 larva L3 puffstage 1-2    1128 larva L3 puffstage 3-6    524 larva L3 puffstage 7-9    662 white prepupae new    941 white prepupae 12hr    363 white prepupae 24hr    378 pupae 2d postWPP    226 pupae 3d postWPP    84 pupae 4d postWPP    304 adult male 01day    2707 adult male 05day    2252 adult male 30day    1916 adult female 01day    1838 adult female 05day    1407 adult female 30day    1631 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    13 embryo 04-06hr    12 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    16 embryo 16-18hr  103 embryo 18-20hr  (371) embryo 20-22hr  (350) embryo 22-24hr  (450) larva L1  (154) larva L2  (187) larva L3 12hr old  (338) larva L3 puffstage 1-2  (1128) larva L3 puffstage 3-6  (524) larva L3 puffstage 7-9  (662) white prepupae new  (941) white prepupae 12hr  (363) white prepupae 24hr  (378) pupae 2d postWPP  (226) pupae 3d postWPP    84 pupae 4d postWPP  (304) adult male 01day  (2707) adult male 05day  (2252) adult male 30day  (1916) adult female 01day  (1838) adult female 05day  (1407) adult female 30day  (1631) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    13 embryo 04-06hr    12 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    16 embryo 16-18hr    103 embryo 18-20hr    371 embryo 20-22hr    350 embryo 22-24hr    450 larva L1    154 larva L2    187 larva L3 12hr old    338 larva L3 puffstage 1-2    1128 larva L3 puffstage 3-6    524 larva L3 puffstage 7-9    662 white prepupae new    941 white prepupae 12hr    363 white prepupae 24hr    378 pupae 2d postWPP    226 pupae 3d postWPP    84 pupae 4d postWPP    304 adult male 01day  (2707) adult male 05day  (2252) adult male 30day  (1916) adult female 01day  (1838) adult female 05day  1407 adult female 30day  (1631) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    13 embryo 04-06hr    12 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    16 embryo 16-18hr    103 embryo 18-20hr    371 embryo 20-22hr    350 embryo 22-24hr    450 larva L1    154 larva L2    187 larva L3 12hr old    338 larva L3 puffstage 1-2    1128 larva L3 puffstage 3-6    524 larva L3 puffstage 7-9    662 white prepupae new    941 white prepupae 12hr    363 white prepupae 24hr    378 pupae 2d postWPP    226 pupae 3d postWPP    84 pupae 4d postWPP    304 adult male 01day    2707 adult male 05day    2252 adult male 30day    1916 adult female 01day    1838 adult female 05day    1407 adult female 30day    1631 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    13 embryo 04-06hr    12 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    16 embryo 16-18hr    103 embryo 18-20hr    371 embryo 20-22hr    350 embryo 22-24hr    450 larva L1    154 larva L2    187 larva L3 12hr old    338 larva L3 puffstage 1-2    1128 larva L3 puffstage 3-6    524 larva L3 puffstage 7-9    662 white prepupae new    941 white prepupae 12hr    363 white prepupae 24hr    378 pupae 2d postWPP    226 pupae 3d postWPP    84 pupae 4d postWPP    304 adult male 01day    2707 adult male 05day    2252 adult male 30day    1916 adult female 01day    1838 adult female 05day    1407 adult female 30day    1631 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0029828 expression level Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    13 embryo 04-06hr    12 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    16 embryo 16-18hr    103 embryo 18-20hr    371 embryo 20-22hr    350 embryo 22-24hr    450 larva L1    154 larva L2    187 larva L3 12hr old    338 larva L3 puffstage 1-2    1128 larva L3 puffstage 3-6    524 larva L3 puffstage 7-9    662 white prepupae new    941 white prepupae 12hr    363 white prepupae 24hr    378 pupae 2d postWPP    226 pupae 3d postWPP    84 pupae 4d postWPP    304 adult male 01day    2707 adult male 05day    2252 adult male 30day    1916 adult female 01day    1838 adult female 05day    1407 adult female 30day    1631 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    13 embryo 04-06hr    12 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    16 embryo 16-18hr  103 embryo 18-20hr  (371) embryo 20-22hr  (350) embryo 22-24hr  (450) larva L1  (154) larva L2  (187) larva L3 12hr old  (338) larva L3 puffstage 1-2  (1128) larva L3 puffstage 3-6  (524) larva L3 puffstage 7-9  (662) white prepupae new  (941) white prepupae 12hr  (363) white prepupae 24hr  (378) pupae 2d postWPP  (226) pupae 3d postWPP    84 pupae 4d postWPP  (304) adult male 01day  (2707) adult male 05day  (2252) adult male 30day  (1916) adult female 01day  (1838) adult female 05day  (1407) adult female 30day  (1631) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    13 embryo 04-06hr    12 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    16 embryo 16-18hr    103 embryo 18-20hr    371 embryo 20-22hr    350 embryo 22-24hr    450 larva L1    154 larva L2    187 larva L3 12hr old    338 larva L3 puffstage 1-2    1128 larva L3 puffstage 3-6    524 larva L3 puffstage 7-9    662 white prepupae new    941 white prepupae 12hr    363 white prepupae 24hr    378 pupae 2d postWPP    226 pupae 3d postWPP    84 pupae 4d postWPP    304 adult male 01day  (2707) adult male 05day  2252 adult male 30day  1916 adult female 01day  1838 adult female 05day  1407 adult female 30day  1631 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    13 embryo 04-06hr    12 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    16 embryo 16-18hr    103 embryo 18-20hr    371 embryo 20-22hr    350 embryo 22-24hr    450 larva L1    154 larva L2    187 larva L3 12hr old    338 larva L3 puffstage 1-2    1128 larva L3 puffstage 3-6    524 larva L3 puffstage 7-9    662 white prepupae new    941 white prepupae 12hr    363 white prepupae 24hr    378 pupae 2d postWPP    226 pupae 3d postWPP    84 pupae 4d postWPP    304 adult male 01day    2707 adult male 05day    2252 adult male 30day    1916 adult female 01day    1838 adult female 05day    1407 adult female 30day    1631 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1 embryo 02-04hr    13 embryo 04-06hr    12 embryo 06-08hr    2 embryo 08-10hr    4 embryo 10-12hr    2 embryo 12-14hr    1 embryo 14-16hr    16 embryo 16-18hr    103 embryo 18-20hr    371 embryo 20-22hr    350 embryo 22-24hr    450 larva L1    154 larva L2    187 larva L3 12hr old    338 larva L3 puffstage 1-2    1128 larva L3 puffstage 3-6    524 larva L3 puffstage 7-9    662 white prepupae new    941 white prepupae 12hr    363 white prepupae 24hr    378 pupae 2d postWPP    226 pupae 3d postWPP    84 pupae 4d postWPP    304 adult male 01day    2707 adult male 05day    2252 adult male 30day    1916 adult female 01day    1838 adult female 05day    1407 adult female 30day    1631 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0029828    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0029828 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: adult midgut, adult heart, adult fat body, adult spermathecae, adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval midgut, larval fat body. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0029828 expression level Tissue   Expression Level Larval Central Nervous System    0.8 Larval Midgut    169.4 Larval Hindgut no informative data Larval Malpighian Tubules    2.4 Larval Fat Body    478.1 Larval Salivary Gland no informative data Larval Trachea    8.95 Larval Carcass    1.825 Adult Head    443.1 Adult Eye    321.65 Adult Brain    13.7 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut    1179.8 Adult Hindgut    52.5 Adult Malpighian Tubules    8.5 Adult Fat Body    1447.1 Adult Salivary Gland    8.4 Adult Heart    710.725 Adult VirginFemale Spermatheca    1374.2 Adult InseminatedFemale Spermatheca    1210.5 Adult Ovary    0.3 Adult Testis    3.3 Adult Male Accessory Gland    1.5 Adult Carcass    532.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    0.8 Larval Midgut    169.4 Larval Hindgut no informative data Larval Malpighian Tubules    2.4 Larval Fat Body    478.1 Larval Salivary Gland no informative data Larval Trachea    8.95 Larval Carcass    1.825 Adult Head    443.1 Adult Eye    321.65 Adult Brain    13.7 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut  (1179.8) Adult Hindgut    52.5 Adult Malpighian Tubules    8.5 Adult Fat Body  (1447.1) Adult Salivary Gland    8.4 Adult Heart  (710.725) Adult VirginFemale Spermatheca  (1374.2) Adult InseminatedFemale Spermatheca  (1210.5) Adult Ovary    0.3 Adult Testis    3.3 Adult Male Accessory Gland    1.5 Adult Carcass  532.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    0.8 Larval Midgut    169.4 Larval Hindgut no informative data Larval Malpighian Tubules    2.4 Larval Fat Body    478.1 Larval Salivary Gland no informative data Larval Trachea    8.95 Larval Carcass    1.825 Adult Head    443.1 Adult Eye    321.65 Adult Brain    13.7 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut  (1179.8) Adult Hindgut    52.5 Adult Malpighian Tubules    8.5 Adult Fat Body  (1447.1) Adult Salivary Gland    8.4 Adult Heart    710.725 Adult VirginFemale Spermatheca  (1374.2) Adult InseminatedFemale Spermatheca  (1210.5) Adult Ovary    0.3 Adult Testis    3.3 Adult Male Accessory Gland    1.5 Adult Carcass    532.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    0.8 Larval Midgut    169.4 Larval Hindgut no informative data Larval Malpighian Tubules    2.4 Larval Fat Body    478.1 Larval Salivary Gland no informative data Larval Trachea    8.95 Larval Carcass    1.825 Adult Head    443.1 Adult Eye    321.65 Adult Brain    13.7 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut    1179.8 Adult Hindgut    52.5 Adult Malpighian Tubules    8.5 Adult Fat Body    1447.1 Adult Salivary Gland    8.4 Adult Heart    710.725 Adult VirginFemale Spermatheca    1374.2 Adult InseminatedFemale Spermatheca    1210.5 Adult Ovary    0.3 Adult Testis    3.3 Adult Male Accessory Gland    1.5 Adult Carcass    532.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0029828 expression level Tissue   Expression Level Larval Central Nervous System    0.8 Larval Midgut    169.4 Larval Hindgut no informative data Larval Malpighian Tubules    2.4 Larval Fat Body    478.1 Larval Salivary Gland no informative data Larval Trachea    8.95 Larval Carcass    1.825 Adult Head    443.1 Adult Eye    321.65 Adult Brain    13.7 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut    1179.8 Adult Hindgut    52.5 Adult Malpighian Tubules    8.5 Adult Fat Body    1447.1 Adult Salivary Gland    8.4 Adult Heart    710.725 Adult VirginFemale Spermatheca    1374.2 Adult InseminatedFemale Spermatheca    1210.5 Adult Ovary    0.3 Adult Testis    3.3 Adult Male Accessory Gland    1.5 Adult Carcass    532.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    0.8 Larval Midgut    169.4 Larval Hindgut no informative data Larval Malpighian Tubules    2.4 Larval Fat Body    478.1 Larval Salivary Gland no informative data Larval Trachea    8.95 Larval Carcass    1.825 Adult Head    443.1 Adult Eye    321.65 Adult Brain    13.7 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut  (1179.8) Adult Hindgut    52.5 Adult Malpighian Tubules    8.5 Adult Fat Body  (1447.1) Adult Salivary Gland    8.4 Adult Heart  710.725 Adult VirginFemale Spermatheca  (1374.2) Adult InseminatedFemale Spermatheca  (1210.5) Adult Ovary    0.3 Adult Testis    3.3 Adult Male Accessory Gland    1.5 Adult Carcass  532.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    0.8 Larval Midgut    169.4 Larval Hindgut no informative data Larval Malpighian Tubules    2.4 Larval Fat Body    478.1 Larval Salivary Gland no informative data Larval Trachea    8.95 Larval Carcass    1.825 Adult Head    443.1 Adult Eye    321.65 Adult Brain    13.7 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut  1179.8 Adult Hindgut    52.5 Adult Malpighian Tubules    8.5 Adult Fat Body  1447.1 Adult Salivary Gland    8.4 Adult Heart    710.725 Adult VirginFemale Spermatheca  1374.2 Adult InseminatedFemale Spermatheca  1210.5 Adult Ovary    0.3 Adult Testis    3.3 Adult Male Accessory Gland    1.5 Adult Carcass    532.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    0.8 Larval Midgut    169.4 Larval Hindgut no informative data Larval Malpighian Tubules    2.4 Larval Fat Body    478.1 Larval Salivary Gland no informative data Larval Trachea    8.95 Larval Carcass    1.825 Adult Head    443.1 Adult Eye    321.65 Adult Brain    13.7 Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut    1179.8 Adult Hindgut    52.5 Adult Malpighian Tubules    8.5 Adult Fat Body    1447.1 Adult Salivary Gland    8.4 Adult Heart    710.725 Adult VirginFemale Spermatheca    1374.2 Adult InseminatedFemale Spermatheca    1210.5 Adult Ovary    0.3 Adult Testis    3.3 Adult Male Accessory Gland    1.5 Adult Carcass    532.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut no informative data Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland no informative data Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion no informative data Adult Crop no informative data Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    443.1   NA  Eye    321.65   NA  Brain    13.7   0.8  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    no informative data   NA  Crop    no informative data   169.4  Midgut    1179.8   no informative data  Hindgut    52.5   2.4  Malpighian Tubules    8.5   478.1  Fat Body    1447.1   no informative data  Salivary Gland    8.4   NA  Heart    710.725   8.95  Trachea    NA   NA  VirginFemale Spermatheca    1374.2   NA  InseminatedFemale Spermatheca    1210.5   NA  Ovary    0.3   NA  Testis    3.3   NA  Male Accessory Gland    1.5   1.825  Carcass    532.9 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_04
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0029828 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6067-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG6067GD3248 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG6067 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG6067 Class Mutagen Stocks Known lesion CG6067GD3248 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG6067KK106327 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD3248} NA P{KK106327} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
serine-type endopeptidase activity inferred from electronic annotation with InterPro:IPR001254 (FlyBase Curators et al., 2004-)
Biological Process
CV term Evidence References
proteolysis inferred from electronic annotation with InterPro:IPR001254 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG6067 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0029828
Orthologs
Genome-wide drosophilid orthologs	Dana\GF22086 Dere\GG18807 Dgri\GH24381 Dmoj\GI15319 Dper\GL14900 Dpse\GA26504 Dsec\GM12457 Dsim\GD16773 Dvir\GJ14757 Dwil\GK20134 Dyak\GE17568
Curated drosophilid orthologs	Dpse\GA19334
Linkouts	OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0235025 FBgn0222131 FBgn0201961 FBgn0188361 FBgn0167394 FBgn0247878 FBgn0152504 FBgn0138068 FBgn0131837 FBgn0111015 FBgn0099085 CPIJ015107 AAEL008080
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v100950 P{KK106327}VIE-260B v7098 w1118; P{GD3248}v7098
Genomic Clones ( 1 )
	BACR07F15 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 34 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RH02936
Other clones	FI02079
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE53252 RE57543
Other clones	EC051145 EC053654 EC053655 EC055584 EC055956 RP003091228 RP003113960 RP003119939 RP003132285 RP003143057 RP003157544 RP003179884 RP003208118 RP003263582 RP003285748 RP003287153 RP003315431 RP003322296 RP003347797 RP003442885 RP003459900 RP003471310 RP003495340 RP003514312 RP003538410 RP003593007 RP003607025 RP003621943 RP003641494 RP003655296
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0029828 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31529
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132055 RefSeq (Proteins) • NP_572283 DDBJ / EMBL / GenBank • AAF46106 AAM48450 AY118421 Entrez Gene - A searchable database of RefSeq genes. • 31529 UniProtKB/TrEMBL • Q8MT25 Q9W452
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Peptidase S1/S6, chymotrypsin/Hap (IPR001254) Peptidase cysteine/serine, trypsin-like (IPR009003)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0029828 DRSC - Results from RNAi screens. • FBgn0029828 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0029828 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG6067-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0029828 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31529 modMine - Data generated by the modENCODE project. • FBgn0029828 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0235025 FBgn0222131 FBgn0201961 FBgn0188361 FBgn0167394 FBgn0247878 FBgn0152504 FBgn0138068 FBgn0131837 FBgn0111015 FBgn0099085 CPIJ015107 AAEL008080
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG6067 (Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 10 )
Research paper	De Gregorio et al., 2002, EMBO J. 21(11): 2568--2579 The Toll and Imd pathways are the major regulators of the immune response in Drosophila. [FBrf0148976]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]