Scaffolding and signaling protein - participates in the reception of an attractive signal that emanates from muscle epidermal attachment sites to direct the motility of developing muscles
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.52
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\Grip using the Feature Mapper tool.
GBrowse - Visual display of RNA-Seq signalsView Dmel\Grip in GBrowse 2
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
Deletion studies show that PDZ domains 1 and 2 have a repressive function on the Grip protein.
RNAi generated by PCR using primers directed to this gene causes a cell growth and viability phenotype when assayed in Kc167 and S2R+ cells.
Grip may participate in the reception of an attractive signal that emanates from the epidermal attachment sites to direct the motility of developing muscles.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
Annotations CG5980 and CG14447 merged as CG14447 in release 3 of the genome annotation.