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Gene Dmel\CG5921

General Information
Symbol	Dmel\CG5921	Species	D. melanogaster
Name		Annotation symbol	CG5921
Feature type	protein_coding_gene	FlyBase ID	FBgn0029835
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	5D3-5D3	Sequence location	X:5,944,861..5,959,679 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG5921 (FBgn0029835). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. One allele is reported. No phenotypic data is available. It has 3 annotated transcripts and 3 annotated polypeptides. Protein features are: PDZ domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed during late larval stages, during late pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult midgut, larval Malpighian tubules. Comments on Affy2 ProbeSet: ProbeSet 1633783_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG5921. Gene sequence location is X:5944861..5959679.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 5D3-5D3   Limits computationally determined from genome sequence between P{EP}EP1457EP1457&P{EP}CG5928EP1083 and P{EP}EP1311&P{EP}EP1384
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG5921 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.48 Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG5921-RC FBtr0305342  NM_132062   4361   829 CG5921-RD FBtr0305343  NM_167058   3373   886 CG5921-RE FBtr0336972  NM_001272336   2827   728
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG5921-PC   FBpp0293885   86.5   829   10.92     NP_572290   AAN09159 CG5921-PD   FBpp0293886   92.4   886   10.96     NP_727061   AAF46116 CG5921-PE   FBpp0307915   75.7   728   10.69     NP_001259265   AGB95111
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • PDZ domain (IPR001478)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF46116   AE014298 AAN09159   AE014298 AGB95111   BT149845   CO190021   CO308524   CO320243   CO344313   EC227562   EC238227   EC241315   EC255085   EV579970   GR705848
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8IRR2 Q9W443
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult midgut, larval Malpighian tubules. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1.25 Larval Midgut    161.5 Larval Hindgut    87.9 Larval Malpighian Tubules    296.2 Larval Fat Body    6.4 Larval Salivary Gland    3.7 Larval Trachea    1.5 Larval Carcass    1.9 Adult Head    12.7 Adult Eye    27.8 Adult Brain    1.4 Adult Thoracic-Abdominal Ganglion    3.2 Adult Crop    13.5 Adult Midgut    358.5 Adult Hindgut    97.4 Adult Malpighian Tubules    72 Adult Fat Body    3.5 Adult Salivary Gland    2.8 Adult Heart    1.675 Adult VirginFemale Spermatheca    3.5 Adult InseminatedFemale Spermatheca    3.2 Adult Ovary    4.3 Adult Testis    0.9 Adult Male Accessory Gland    5.1 Adult Carcass    11 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    1.25 Larval Midgut    161.5 Larval Hindgut    87.9 Larval Malpighian Tubules    296.2 Larval Fat Body    6.4 Larval Salivary Gland    3.7 Larval Trachea    1.5 Larval Carcass    1.9 Adult Head    12.7 Adult Eye    27.8 Adult Brain    1.4 Adult Thoracic-Abdominal Ganglion    3.2 Adult Crop    13.5 Adult Midgut    358.5 Adult Hindgut    97.4 Adult Malpighian Tubules    72 Adult Fat Body    3.5 Adult Salivary Gland    2.8 Adult Heart    1.675 Adult VirginFemale Spermatheca    3.5 Adult InseminatedFemale Spermatheca    3.2 Adult Ovary    4.3 Adult Testis    0.9 Adult Male Accessory Gland    5.1 Adult Carcass    11 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    1.25 Larval Midgut    161.5 Larval Hindgut    87.9 Larval Malpighian Tubules    296.2 Larval Fat Body    6.4 Larval Salivary Gland    3.7 Larval Trachea    1.5 Larval Carcass    1.9 Adult Head    12.7 Adult Eye    27.8 Adult Brain    1.4 Adult Thoracic-Abdominal Ganglion    3.2 Adult Crop    13.5 Adult Midgut    358.5 Adult Hindgut    97.4 Adult Malpighian Tubules    72 Adult Fat Body    3.5 Adult Salivary Gland    2.8 Adult Heart    1.675 Adult VirginFemale Spermatheca    3.5 Adult InseminatedFemale Spermatheca    3.2 Adult Ovary    4.3 Adult Testis    0.9 Adult Male Accessory Gland    5.1 Adult Carcass    11 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1.25 Larval Midgut    161.5 Larval Hindgut    87.9 Larval Malpighian Tubules    296.2 Larval Fat Body    6.4 Larval Salivary Gland    3.7 Larval Trachea    1.5 Larval Carcass    1.9 Adult Head    12.7 Adult Eye    27.8 Adult Brain    1.4 Adult Thoracic-Abdominal Ganglion    3.2 Adult Crop    13.5 Adult Midgut    358.5 Adult Hindgut    97.4 Adult Malpighian Tubules    72 Adult Fat Body    3.5 Adult Salivary Gland    2.8 Adult Heart    1.675 Adult VirginFemale Spermatheca    3.5 Adult InseminatedFemale Spermatheca    3.2 Adult Ovary    4.3 Adult Testis    0.9 Adult Male Accessory Gland    5.1 Adult Carcass    11 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    1.25 Larval Midgut    161.5 Larval Hindgut    87.9 Larval Malpighian Tubules    296.2 Larval Fat Body    6.4 Larval Salivary Gland    3.7 Larval Trachea    1.5 Larval Carcass    1.9 Adult Head    12.7 Adult Eye    27.8 Adult Brain    1.4 Adult Thoracic-Abdominal Ganglion    3.2 Adult Crop    13.5 Adult Midgut    358.5 Adult Hindgut    97.4 Adult Malpighian Tubules    72 Adult Fat Body    3.5 Adult Salivary Gland    2.8 Adult Heart    1.675 Adult VirginFemale Spermatheca    3.5 Adult InseminatedFemale Spermatheca    3.2 Adult Ovary    4.3 Adult Testis    0.9 Adult Male Accessory Gland    5.1 Adult Carcass    11 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    1.25 Larval Midgut    161.5 Larval Hindgut    87.9 Larval Malpighian Tubules    296.2 Larval Fat Body    6.4 Larval Salivary Gland    3.7 Larval Trachea    1.5 Larval Carcass    1.9 Adult Head    12.7 Adult Eye    27.8 Adult Brain    1.4 Adult Thoracic-Abdominal Ganglion    3.2 Adult Crop    13.5 Adult Midgut    358.5 Adult Hindgut    97.4 Adult Malpighian Tubules    72 Adult Fat Body    3.5 Adult Salivary Gland    2.8 Adult Heart    1.675 Adult VirginFemale Spermatheca    3.5 Adult InseminatedFemale Spermatheca    3.2 Adult Ovary    4.3 Adult Testis    0.9 Adult Male Accessory Gland    5.1 Adult Carcass    11 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    1.25 Larval Midgut    161.5 Larval Hindgut    87.9 Larval Malpighian Tubules    296.2 Larval Fat Body    6.4 Larval Salivary Gland    3.7 Larval Trachea    1.5 Larval Carcass    1.9 Adult Head    12.7 Adult Eye    27.8 Adult Brain    1.4 Adult Thoracic-Abdominal Ganglion    3.2 Adult Crop    13.5 Adult Midgut    358.5 Adult Hindgut    97.4 Adult Malpighian Tubules    72 Adult Fat Body    3.5 Adult Salivary Gland    2.8 Adult Heart    1.675 Adult VirginFemale Spermatheca    3.5 Adult InseminatedFemale Spermatheca    3.2 Adult Ovary    4.3 Adult Testis    0.9 Adult Male Accessory Gland    5.1 Adult Carcass    11 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    1.25 Larval Midgut    161.5 Larval Hindgut    87.9 Larval Malpighian Tubules    296.2 Larval Fat Body    6.4 Larval Salivary Gland    3.7 Larval Trachea    1.5 Larval Carcass    1.9 Adult Head    12.7 Adult Eye    27.8 Adult Brain    1.4 Adult Thoracic-Abdominal Ganglion    3.2 Adult Crop    13.5 Adult Midgut    358.5 Adult Hindgut    97.4 Adult Malpighian Tubules    72 Adult Fat Body    3.5 Adult Salivary Gland    2.8 Adult Heart    1.675 Adult VirginFemale Spermatheca    3.5 Adult InseminatedFemale Spermatheca    3.2 Adult Ovary    4.3 Adult Testis    0.9 Adult Male Accessory Gland    5.1 Adult Carcass    11 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    no informative data   NA  Eye    no informative data   NA  Brain    1.4   1.25  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    3.2   NA  Crop    no informative data   161.5  Midgut    358.5   87.9  Hindgut    97.4   296.2  Malpighian Tubules    72   6.4  Fat Body    3.5   3.7  Salivary Gland    2.8   NA  Heart    1.675   1.5  Trachea    NA   NA  VirginFemale Spermatheca    3.5   NA  InseminatedFemale Spermatheca    3.2   NA  Ovary    4.3   NA  Testis    0.9   NA  Male Accessory Gland    5.1   1.9  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    0 central nervous system, pupae P8    2 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    31 digestive system, 1-day adult    13 digestive system, 4-day adult    12 digestive system, 20-day adult    13 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    10 carcass, larvae L3 wandering    1 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    0 central nervous system, pupae P8    2 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering  (31) digestive system, 1-day adult    13 digestive system, 4-day adult    12 digestive system, 20-day adult    13 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    10 carcass, larvae L3 wandering    1 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    0 central nervous system, pupae P8    2 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    31 digestive system, 1-day adult    13 digestive system, 4-day adult    12 digestive system, 20-day adult    13 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    10 carcass, larvae L3 wandering    1 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    0 central nervous system, pupae P8    2 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    31 digestive system, 1-day adult    13 digestive system, 4-day adult    12 digestive system, 20-day adult    13 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    10 carcass, larvae L3 wandering    1 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    0 central nervous system, pupae P8    2 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    31 digestive system, 1-day adult    13 digestive system, 4-day adult    12 digestive system, 20-day adult    13 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    10 carcass, larvae L3 wandering    1 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    0 central nervous system, pupae P8    2 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering  31 digestive system, 1-day adult    13 digestive system, 4-day adult    12 digestive system, 20-day adult    13 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    10 carcass, larvae L3 wandering    1 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    0 central nervous system, pupae P8    2 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    31 digestive system, 1-day adult    13 digestive system, 4-day adult    12 digestive system, 20-day adult    13 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    10 carcass, larvae L3 wandering    1 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    2 central nervous system, larvae L3    0 central nervous system, pupae P8    2 head, virgin 1-day female    1 head, virgin 4-day female    1 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    2 head, mated 20-day male    2 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    31 digestive system, 1-day adult    13 digestive system, 4-day adult    12 digestive system, 20-day adult    13 fat body, larvae L3 wandering    0 fat body, white prepupae    1 fat body, pupae P8    10 carcass, larvae L3 wandering    1 carcass, 1-day adult    1 carcass, 4-day adult    1 carcass, 20-day adult    1 ovary, virgin 4-day female    0 ovary, mated 4-day female    0 testis, mated 4-day male    0 accessory gland, mated 4-day male    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of extremely low expression. Peak expression observed during late larval stages, during late pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    3 embryo 14-16hr    8 embryo 16-18hr    7 embryo 18-20hr    5 embryo 20-22hr    8 embryo 22-24hr    7 larva L1    5 larva L2    5 larva L3 12hr old    3 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    3 white prepupae 24hr    3 pupae 2d postWPP    19 pupae 3d postWPP    6 pupae 4d postWPP    2 adult male 01day    4 adult male 05day    5 adult male 30day    5 adult female 01day    5 adult female 05day    4 adult female 30day    3 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    3 embryo 14-16hr    8 embryo 16-18hr    7 embryo 18-20hr    5 embryo 20-22hr    8 embryo 22-24hr    7 larva L1    5 larva L2    5 larva L3 12hr old    3 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    3 white prepupae 24hr    3 pupae 2d postWPP    19 pupae 3d postWPP    6 pupae 4d postWPP    2 adult male 01day    4 adult male 05day    5 adult male 30day    5 adult female 01day    5 adult female 05day    4 adult female 30day    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    3 embryo 14-16hr    8 embryo 16-18hr    7 embryo 18-20hr    5 embryo 20-22hr    8 embryo 22-24hr    7 larva L1    5 larva L2    5 larva L3 12hr old    3 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    3 white prepupae 24hr    3 pupae 2d postWPP    19 pupae 3d postWPP    6 pupae 4d postWPP    2 adult male 01day    4 adult male 05day    5 adult male 30day    5 adult female 01day    5 adult female 05day    4 adult female 30day    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    3 embryo 14-16hr    8 embryo 16-18hr    7 embryo 18-20hr    5 embryo 20-22hr    8 embryo 22-24hr    7 larva L1    5 larva L2    5 larva L3 12hr old    3 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    3 white prepupae 24hr    3 pupae 2d postWPP    19 pupae 3d postWPP    6 pupae 4d postWPP    2 adult male 01day    4 adult male 05day    5 adult male 30day    5 adult female 01day    5 adult female 05day    4 adult female 30day    3 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    3 embryo 14-16hr    8 embryo 16-18hr    7 embryo 18-20hr    5 embryo 20-22hr    8 embryo 22-24hr    7 larva L1    5 larva L2    5 larva L3 12hr old    3 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    3 white prepupae 24hr    3 pupae 2d postWPP    19 pupae 3d postWPP    6 pupae 4d postWPP    2 adult male 01day    4 adult male 05day    5 adult male 30day    5 adult female 01day    5 adult female 05day    4 adult female 30day    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    3 embryo 14-16hr    8 embryo 16-18hr    7 embryo 18-20hr    5 embryo 20-22hr    8 embryo 22-24hr    7 larva L1    5 larva L2    5 larva L3 12hr old    3 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    3 white prepupae 24hr    3 pupae 2d postWPP    19 pupae 3d postWPP    6 pupae 4d postWPP    2 adult male 01day    4 adult male 05day    5 adult male 30day    5 adult female 01day    5 adult female 05day    4 adult female 30day    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    3 embryo 14-16hr    8 embryo 16-18hr    7 embryo 18-20hr    5 embryo 20-22hr    8 embryo 22-24hr    7 larva L1    5 larva L2    5 larva L3 12hr old    3 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    3 white prepupae 24hr    3 pupae 2d postWPP    19 pupae 3d postWPP    6 pupae 4d postWPP    2 adult male 01day    4 adult male 05day    5 adult male 30day    5 adult female 01day    5 adult female 05day    4 adult female 30day    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    0 embryo 02-04hr    0 embryo 04-06hr    0 embryo 06-08hr    0 embryo 08-10hr    0 embryo 10-12hr    2 embryo 12-14hr    3 embryo 14-16hr    8 embryo 16-18hr    7 embryo 18-20hr    5 embryo 20-22hr    8 embryo 22-24hr    7 larva L1    5 larva L2    5 larva L3 12hr old    3 larva L3 puffstage 1-2    4 larva L3 puffstage 3-6    6 larva L3 puffstage 7-9    13 white prepupae new    12 white prepupae 12hr    3 white prepupae 24hr    3 pupae 2d postWPP    19 pupae 3d postWPP    6 pupae 4d postWPP    2 adult male 01day    4 adult male 05day    5 adult male 30day    5 adult female 01day    5 adult female 05day    4 adult female 30day    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    6 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    6 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    6 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    6 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    6 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    6 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    6 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    5 cold shock, 4-day adult    6 heat shock, 4-day adult    2 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    5 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    1 Copper 0.5 mM 12 hrs, larvae L3    5 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    6 Zinc 4.5 mM 48 hrs, 4-day adult    1 Ethanol 2.5% 3 hrs, larvae L3    2 Ethanol 5% 3 hrs, larvae L3    4 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    1 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    2 Paraquat 10 mM 48 hrs, 4-day adult    2 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_18 mE1_20_mRNA_expression_cluster_11
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0029835 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5921-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG5921GD5137 Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG5921 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG5921 Class Mutagen Stocks Known lesion CG5921GD5137 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD5137} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG5921 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 58034 DroID - A comprehensive database of gene and protein interactions. • FBgn0029835 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31538 SignaLink - A protein-protein and protein-miRNA interaction database with multi-layered structure and multiple confidence scores. • Q8IRR2
Orthologs
OrthoDB Orthologs (34) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6MCXK1 Dipteran inclusive ortholog search EOG6MKNQM Insect inclusive ortholog search EOG6M3853 Arthropod inclusive ortholog search EOG6DNCKX Metazoa inclusive ortholog search EOG6XWTQN
Orthologs in Drosophila Species (EOG6MCXK1)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG5921     Drosophila simulans   Dsim\GD16780     Drosophila sechellia   Dsec\GM12462 Y   Drosophila erecta   Dere\GG18812 Y   Drosophila yakuba   Dyak\GE17575     Drosophila ananassae   Dana\GF20367 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA26523     Drosophila persimilis   Dper\GL14906 Y   Drosophila willistoni   Dwil\GK15791     Drosophila grimshawi   Dgri\GH24848 Y
Orthologs in non-Drosophila Dipterans (EOG6MKNQM)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL005634   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ012732
Orthologs in non-Dipteran Insects (EOG6M3853)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\GB53844   Apis mellifera Western honey bee  Amel\GB55356   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG020634   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH27100   Atta cephalotes Leafcutter ant  Acep\ACEP18623   Camponotus floridanus Florida carpenter ant  Cflo\CFLO13120   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL14230   Linepithema humile Argentine ant  Lhum\LH14980   Pogonomyrmex barbatus Red harvester ant  Pbar\PB14027   Solenopsis invicta Red fire ant  Sinv\SINV18813   Bombyx mori Silkmoth  Bmor\BGIBMGA000929   Pediculus humanus Human body louse  Phum\PHUM503270   Tribolium castaneum Red flour beetle  Tcas\GLEAN_07147
Orthologs in non-Insect Arthropods (EOG6DNCKX)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Ixodes scapularis Deer tick  Isca\ISCW015785
Orthologs in non-Arthropod Metazoa (EOG6XWTQN)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_028159gn   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_009191gn   Danio rerio Zebrafish  Drer\ush1c   Xenopus tropicalis Western clawed frog  Xtro\ENSXETG00000030644   Gallus gallus Domestic chicken  Ggal\USH1C   Mus musculus House mouse  Mmus\ENSMUSG00000030838   Rattus norvegicus Norway rat  Rnor\Ush1c   Homo sapiens Human  Hsap\USH1C
Human Orthologs (1)
Gene OMIM HGNC Hsap\USH1C
AAA Orthologs (7) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila sechellia Dsec\GM12462 Drosophila erecta Dere\GG18812 Drosophila ananassae Dana\GF20367 Drosophila persimilis Dper\GL14906 Drosophila virilis Dvir\GJ16672 Drosophila mojavensis Dmoj\GI16183 Drosophila grimshawi Dgri\GH24848
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v37874 w1118; P{GD5137}v37874 v37875 w1118; P{GD5137}v37875
Genomic Clones ( 2 )
	BACR07F10 BACR07F15 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 11 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones	MIP36432
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones	155898 177613 214383.57 CK01.57D.C5 Dmel_dig_008381_0664_1412 EK046011 EK258615 EK283030 EP19037 MB6-CG5921-RB
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0029835 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31538
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
	dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology. (Kiger et al., 2003)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132062 NM_167058 NM_001272336 RefSeq (Proteins) • NP_572290 NP_727061 NP_001259265 DDBJ / EMBL / GenBank • AAF46116 AAN09159 AGB95111 Entrez Gene - A searchable database of RefSeq genes. • 31538 UniProtKB/TrEMBL • Q8IRR2 Q9W443
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • PDZ domain (IPR001478)
Linkouts
	BioGRID - A database of protein and genetic interactions • 58034 DroID - A comprehensive database of gene and protein interactions. • FBgn0029835 DRSC - Results from RNAi screens. • FBgn0029835 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0029835 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5921-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0029835 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31538 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31538 modMine - Data generated by the modENCODE project. • FBgn0029835 SignaLink - A protein-protein and protein-miRNA interaction database with multi-layered structure and multiple confidence scores. • Q8IRR2
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG5921
Name Synonym
Secondary FlyBase IDs
References ( 10 )
Research paper	Krauchunas et al., 2012, Dev. Biol. 370(1): 125--134 Protein phosphorylation changes reveal new candidates in the regulation of egg activation and early embryogenesis in D. melanogaster. [FBrf0219342]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Kiger et al., 2003, J. Biol. 2(4): Additional data file 1: The gene identity and primer sequences for dsRNAs used in the RNAi screens. [FBrf0174231]
Personal communication to FlyBase	Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Curated genome annotation	FamiliarityBreedsContempt, 1999.11, [Automatic annotations performed at the Celera Jamboreee.] [Automatic annotations performed at the Celera Jamboreee.] [FBrf0126705] Find Enzymes, 1999.11, [Automatic annotations performed at the Celera Jamboreee.] [Automatic annotations performed at the Celera Jamboreee.] [FBrf0126664]