• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • RNA-Seq Search
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • GBrowse 2 Beta
    • CytoSearch
    • Feature Mapper
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Current release
  • Archived releases
  • Map Conversion
  • FTP site:
  • Releases (FTP)
  • Genomes (FTP)
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Vectors & Constructs
  • Other links:
  • BDGP
  • DGRC
  • DIS by issue
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\Corp

General Information
Symbol	Dmel\Corp	Species	D. melanogaster
Name	Companion of reaper	Annotation symbol	CG10965
Feature type	protein_coding_gene	FlyBase ID	FBgn0030028
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	7E1-7E1	Sequence location	X:8,163,931..8,165,442 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene Companion of reaper is referred to in FlyBase by the symbol Dmel\Corp (CG10965, FBgn0030028). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. It is reported to be involved in the biological process: intrinsic apoptotic signaling pathway in response to DNA damage. 5 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed during early pupal stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1641082_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of Corp. Gene sequence location is X:8163931..8165442.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 7E1-7E1   Limits computationally determined from genome sequence between P{EP}CG1632EP1583 and P{EP}MoeEP1652
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\Corp for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.50
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) Corp-RA FBtr0071179  NM_132240   1084   213 Corp-RB FBtr0307283  NM_001258649   1216   213
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein Corp-PA   FBpp0071127   24.6   213   7.86     NP_572468   AAF46358 Corp-PB   FBpp0298284   24.6   213   7.86     NP_001245578   AFH07292
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF46358   AE014298 AFH07292   AI513963   AW941037   AY060803 AAL28351   AY180959 AAO62566   BI227909   BI235709   BI236506   BP559652   CA804082   CA804398   CA804706   CA806444   CA806660   CZ486584   CZ488771   CZ488772   CZ490122   EV596216   GH742540   GH742974   GH743092   GH763486   GH765844
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9W3G9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012) Comment:rapidly degraded yolk nucleus   (Fisher et al., 2012) embryonic stage 7 -- 8   yolk nucleus   (Fisher et al., 2012) embryonic stage 9 -- 10   yolk nucleus   (Fisher et al., 2012) northern blot Stage Tissue/Position (including subcellular localization) Reference pupal stage   salivary gland   (Lee et al., 2003)
Additional Descriptive Data
	The expression of this gene along with several others is induced in salivary glands in pupae at the time of head eversion. This stage is characterized by an increase in the ecdysone titer as well as large amounts of cell death in this tissue. (Lee et al., 2003)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    63.6 Larval Midgut    5.8 Larval Hindgut    9.8 Larval Malpighian Tubules    8.1 Larval Fat Body    9.6 Larval Salivary Gland    6.8 Larval Trachea    23.925 Larval Carcass    54.325 Adult Head    11.8 Adult Eye    7.9 Adult Brain    14.8 Adult Thoracic-Abdominal Ganglion    17.1 Adult Crop    8.1 Adult Midgut    10 Adult Hindgut    13.1 Adult Malpighian Tubules    5 Adult Fat Body    10.2 Adult Salivary Gland    8.6 Adult Heart    15.925 Adult VirginFemale Spermatheca    10.6 Adult InseminatedFemale Spermatheca    12.4 Adult Ovary    271.9 Adult Testis    3.9 Adult Male Accessory Gland    9 Adult Carcass    20.6 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    63.6 Larval Midgut    5.8 Larval Hindgut    9.8 Larval Malpighian Tubules    8.1 Larval Fat Body    9.6 Larval Salivary Gland    6.8 Larval Trachea    23.925 Larval Carcass    54.325 Adult Head    11.8 Adult Eye    7.9 Adult Brain    14.8 Adult Thoracic-Abdominal Ganglion    17.1 Adult Crop    8.1 Adult Midgut    10 Adult Hindgut    13.1 Adult Malpighian Tubules    5 Adult Fat Body    10.2 Adult Salivary Gland    8.6 Adult Heart    15.925 Adult VirginFemale Spermatheca    10.6 Adult InseminatedFemale Spermatheca    12.4 Adult Ovary    271.9 Adult Testis    3.9 Adult Male Accessory Gland    9 Adult Carcass    20.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    63.6 Larval Midgut    5.8 Larval Hindgut    9.8 Larval Malpighian Tubules    8.1 Larval Fat Body    9.6 Larval Salivary Gland    6.8 Larval Trachea    23.925 Larval Carcass    54.325 Adult Head    11.8 Adult Eye    7.9 Adult Brain    14.8 Adult Thoracic-Abdominal Ganglion    17.1 Adult Crop    8.1 Adult Midgut    10 Adult Hindgut    13.1 Adult Malpighian Tubules    5 Adult Fat Body    10.2 Adult Salivary Gland    8.6 Adult Heart    15.925 Adult VirginFemale Spermatheca    10.6 Adult InseminatedFemale Spermatheca    12.4 Adult Ovary    271.9 Adult Testis    3.9 Adult Male Accessory Gland    9 Adult Carcass    20.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    63.6 Larval Midgut    5.8 Larval Hindgut    9.8 Larval Malpighian Tubules    8.1 Larval Fat Body    9.6 Larval Salivary Gland    6.8 Larval Trachea    23.925 Larval Carcass    54.325 Adult Head    11.8 Adult Eye    7.9 Adult Brain    14.8 Adult Thoracic-Abdominal Ganglion    17.1 Adult Crop    8.1 Adult Midgut    10 Adult Hindgut    13.1 Adult Malpighian Tubules    5 Adult Fat Body    10.2 Adult Salivary Gland    8.6 Adult Heart    15.925 Adult VirginFemale Spermatheca    10.6 Adult InseminatedFemale Spermatheca    12.4 Adult Ovary    271.9 Adult Testis    3.9 Adult Male Accessory Gland    9 Adult Carcass    20.6 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    63.6 Larval Midgut    5.8 Larval Hindgut    9.8 Larval Malpighian Tubules    8.1 Larval Fat Body    9.6 Larval Salivary Gland    6.8 Larval Trachea    23.925 Larval Carcass    54.325 Adult Head    11.8 Adult Eye    7.9 Adult Brain    14.8 Adult Thoracic-Abdominal Ganglion    17.1 Adult Crop    8.1 Adult Midgut    10 Adult Hindgut    13.1 Adult Malpighian Tubules    5 Adult Fat Body    10.2 Adult Salivary Gland    8.6 Adult Heart    15.925 Adult VirginFemale Spermatheca    10.6 Adult InseminatedFemale Spermatheca    12.4 Adult Ovary    271.9 Adult Testis    3.9 Adult Male Accessory Gland    9 Adult Carcass    20.6 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    63.6 Larval Midgut    5.8 Larval Hindgut    9.8 Larval Malpighian Tubules    8.1 Larval Fat Body    9.6 Larval Salivary Gland    6.8 Larval Trachea    23.925 Larval Carcass    54.325 Adult Head    11.8 Adult Eye    7.9 Adult Brain    14.8 Adult Thoracic-Abdominal Ganglion    17.1 Adult Crop    8.1 Adult Midgut    10 Adult Hindgut    13.1 Adult Malpighian Tubules    5 Adult Fat Body    10.2 Adult Salivary Gland    8.6 Adult Heart    15.925 Adult VirginFemale Spermatheca    10.6 Adult InseminatedFemale Spermatheca    12.4 Adult Ovary    271.9 Adult Testis    3.9 Adult Male Accessory Gland    9 Adult Carcass    20.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    63.6 Larval Midgut    5.8 Larval Hindgut    9.8 Larval Malpighian Tubules    8.1 Larval Fat Body    9.6 Larval Salivary Gland    6.8 Larval Trachea    23.925 Larval Carcass    54.325 Adult Head    11.8 Adult Eye    7.9 Adult Brain    14.8 Adult Thoracic-Abdominal Ganglion    17.1 Adult Crop    8.1 Adult Midgut    10 Adult Hindgut    13.1 Adult Malpighian Tubules    5 Adult Fat Body    10.2 Adult Salivary Gland    8.6 Adult Heart    15.925 Adult VirginFemale Spermatheca    10.6 Adult InseminatedFemale Spermatheca    12.4 Adult Ovary    271.9 Adult Testis    3.9 Adult Male Accessory Gland    9 Adult Carcass    20.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    63.6 Larval Midgut    5.8 Larval Hindgut    9.8 Larval Malpighian Tubules    8.1 Larval Fat Body    9.6 Larval Salivary Gland    6.8 Larval Trachea    23.925 Larval Carcass    54.325 Adult Head    11.8 Adult Eye    7.9 Adult Brain    14.8 Adult Thoracic-Abdominal Ganglion    17.1 Adult Crop    8.1 Adult Midgut    10 Adult Hindgut    13.1 Adult Malpighian Tubules    5 Adult Fat Body    10.2 Adult Salivary Gland    8.6 Adult Heart    15.925 Adult VirginFemale Spermatheca    10.6 Adult InseminatedFemale Spermatheca    12.4 Adult Ovary    271.9 Adult Testis    3.9 Adult Male Accessory Gland    9 Adult Carcass    20.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    no informative data   NA  Eye    7.9   NA  Brain    14.8   63.6  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    17.1   NA  Crop    8.1   5.8  Midgut    no informative data   9.8  Hindgut    no informative data   8.1  Malpighian Tubules    5   9.6  Fat Body    no informative data   6.8  Salivary Gland    8.6   NA  Heart    15.925   23.925  Trachea    NA   NA  VirginFemale Spermatheca    no informative data   NA  InseminatedFemale Spermatheca    no informative data   NA  Ovary    271.9   NA  Testis    3.9   NA  Male Accessory Gland    9   54.325  Carcass    no informative data FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    3 central nervous system, pupae P8    2 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    2 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    1 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    7 carcass, 4-day adult    4 carcass, 20-day adult    2 ovary, virgin 4-day female    32 ovary, mated 4-day female    22 testis, mated 4-day male    0 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    3 central nervous system, pupae P8    2 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    2 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    1 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    7 carcass, 4-day adult    4 carcass, 20-day adult    2 ovary, virgin 4-day female  (32) ovary, mated 4-day female    22 testis, mated 4-day male    0 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    3 central nervous system, pupae P8    2 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    2 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    1 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    7 carcass, 4-day adult    4 carcass, 20-day adult    2 ovary, virgin 4-day female    32 ovary, mated 4-day female    22 testis, mated 4-day male    0 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    3 central nervous system, pupae P8    2 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    2 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    1 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    7 carcass, 4-day adult    4 carcass, 20-day adult    2 ovary, virgin 4-day female    32 ovary, mated 4-day female    22 testis, mated 4-day male    0 accessory gland, mated 4-day male    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    3 central nervous system, pupae P8    2 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    2 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    1 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    7 carcass, 4-day adult    4 carcass, 20-day adult    2 ovary, virgin 4-day female    32 ovary, mated 4-day female    22 testis, mated 4-day male    0 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    3 central nervous system, pupae P8    2 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    2 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    1 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    7 carcass, 4-day adult    4 carcass, 20-day adult    2 ovary, virgin 4-day female  32 ovary, mated 4-day female    22 testis, mated 4-day male    0 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    3 central nervous system, pupae P8    2 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    2 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    1 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    7 carcass, 4-day adult    4 carcass, 20-day adult    2 ovary, virgin 4-day female    32 ovary, mated 4-day female    22 testis, mated 4-day male    0 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    1 central nervous system, larvae L3    3 central nervous system, pupae P8    2 head, virgin 1-day female    2 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    1 head, mated 4-day female    2 head, mated 20-day female    1 head, mated 1-day male    2 head, mated 4-day male    1 head, mated 20-day male    1 salivary gland, larvae L3 wandering    0 salivary gland, white prepupae    0 digestive system, larvae L3 wandering    0 digestive system, 1-day adult    1 digestive system, 4-day adult    1 digestive system, 20-day adult    1 fat body, larvae L3 wandering    0 fat body, white prepupae    0 fat body, pupae P8    0 carcass, larvae L3 wandering    2 carcass, 1-day adult    7 carcass, 4-day adult    4 carcass, 20-day adult    2 ovary, virgin 4-day female    32 ovary, mated 4-day female    22 testis, mated 4-day male    0 accessory gland, mated 4-day male    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of very low expression. Peak expression observed during early pupal stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    28 embryo 02-04hr    23 embryo 04-06hr    18 embryo 06-08hr    10 embryo 08-10hr    7 embryo 10-12hr    5 embryo 12-14hr    3 embryo 14-16hr    2 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    1 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    61 white prepupae 24hr    35 pupae 2d postWPP    19 pupae 3d postWPP    5 pupae 4d postWPP    3 adult male 01day    5 adult male 05day    3 adult male 30day    2 adult female 01day    12 adult female 05day    19 adult female 30day    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (28) embryo 02-04hr    23 embryo 04-06hr    18 embryo 06-08hr    10 embryo 08-10hr    7 embryo 10-12hr    5 embryo 12-14hr    3 embryo 14-16hr    2 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    1 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr  (61) white prepupae 24hr  (35) pupae 2d postWPP    19 pupae 3d postWPP    5 pupae 4d postWPP    3 adult male 01day    5 adult male 05day    3 adult male 30day    2 adult female 01day    12 adult female 05day    19 adult female 30day    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    28 embryo 02-04hr    23 embryo 04-06hr    18 embryo 06-08hr    10 embryo 08-10hr    7 embryo 10-12hr    5 embryo 12-14hr    3 embryo 14-16hr    2 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    1 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    61 white prepupae 24hr    35 pupae 2d postWPP    19 pupae 3d postWPP    5 pupae 4d postWPP    3 adult male 01day    5 adult male 05day    3 adult male 30day    2 adult female 01day    12 adult female 05day    19 adult female 30day    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    28 embryo 02-04hr    23 embryo 04-06hr    18 embryo 06-08hr    10 embryo 08-10hr    7 embryo 10-12hr    5 embryo 12-14hr    3 embryo 14-16hr    2 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    1 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    61 white prepupae 24hr    35 pupae 2d postWPP    19 pupae 3d postWPP    5 pupae 4d postWPP    3 adult male 01day    5 adult male 05day    3 adult male 30day    2 adult female 01day    12 adult female 05day    19 adult female 30day    15 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    28 embryo 02-04hr    23 embryo 04-06hr    18 embryo 06-08hr    10 embryo 08-10hr    7 embryo 10-12hr    5 embryo 12-14hr    3 embryo 14-16hr    2 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    1 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    61 white prepupae 24hr    35 pupae 2d postWPP    19 pupae 3d postWPP    5 pupae 4d postWPP    3 adult male 01day    5 adult male 05day    3 adult male 30day    2 adult female 01day    12 adult female 05day    19 adult female 30day    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  28 embryo 02-04hr    23 embryo 04-06hr    18 embryo 06-08hr    10 embryo 08-10hr    7 embryo 10-12hr    5 embryo 12-14hr    3 embryo 14-16hr    2 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    1 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr  (61) white prepupae 24hr  (35) pupae 2d postWPP    19 pupae 3d postWPP    5 pupae 4d postWPP    3 adult male 01day    5 adult male 05day    3 adult male 30day    2 adult female 01day    12 adult female 05day    19 adult female 30day    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    28 embryo 02-04hr    23 embryo 04-06hr    18 embryo 06-08hr    10 embryo 08-10hr    7 embryo 10-12hr    5 embryo 12-14hr    3 embryo 14-16hr    2 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    1 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    61 white prepupae 24hr    35 pupae 2d postWPP    19 pupae 3d postWPP    5 pupae 4d postWPP    3 adult male 01day    5 adult male 05day    3 adult male 30day    2 adult female 01day    12 adult female 05day    19 adult female 30day    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    28 embryo 02-04hr    23 embryo 04-06hr    18 embryo 06-08hr    10 embryo 08-10hr    7 embryo 10-12hr    5 embryo 12-14hr    3 embryo 14-16hr    2 embryo 16-18hr    1 embryo 18-20hr    1 embryo 20-22hr    1 embryo 22-24hr    1 larva L1    1 larva L2    1 larva L3 12hr old    1 larva L3 puffstage 1-2    3 larva L3 puffstage 3-6    2 larva L3 puffstage 7-9    3 white prepupae new    3 white prepupae 12hr    61 white prepupae 24hr    35 pupae 2d postWPP    19 pupae 3d postWPP    5 pupae 4d postWPP    3 adult male 01day    5 adult male 05day    3 adult male 30day    2 adult female 01day    12 adult female 05day    19 adult female 30day    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    1 embryonic 1182-4H    1 embryonic GM2    1 embryonic Kc167    2 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    2 wing disc ML-DmD8    5 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    2 wing disc ML-DmD21    4 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    10 mixed discs ML-DmD4-c1    1 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    6 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    1 embryonic 1182-4H    1 embryonic GM2    1 embryonic Kc167    2 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    2 wing disc ML-DmD8    5 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    2 wing disc ML-DmD21    4 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    10 mixed discs ML-DmD4-c1    1 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    6 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    1 embryonic 1182-4H    1 embryonic GM2    1 embryonic Kc167    2 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    2 wing disc ML-DmD8    5 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    2 wing disc ML-DmD21    4 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    10 mixed discs ML-DmD4-c1    1 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    6 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    1 embryonic 1182-4H    1 embryonic GM2    1 embryonic Kc167    2 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    2 wing disc ML-DmD8    5 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    2 wing disc ML-DmD21    4 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    10 mixed discs ML-DmD4-c1    1 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    6 ovary OSS    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    1 embryonic 1182-4H    1 embryonic GM2    1 embryonic Kc167    2 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    2 wing disc ML-DmD8    5 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    2 wing disc ML-DmD21    4 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    10 mixed discs ML-DmD4-c1    1 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    6 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    1 embryonic 1182-4H    1 embryonic GM2    1 embryonic Kc167    2 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    2 wing disc ML-DmD8    5 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    2 wing disc ML-DmD21    4 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    10 mixed discs ML-DmD4-c1    1 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    6 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    1 embryonic 1182-4H    1 embryonic GM2    1 embryonic Kc167    2 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    2 wing disc ML-DmD8    5 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    2 wing disc ML-DmD21    4 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    10 mixed discs ML-DmD4-c1    1 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    6 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    1 Schneider line 2 Sg4    1 embryonic 1182-4H    1 embryonic GM2    1 embryonic Kc167    2 embryonic S1    0 embryonic S3    0 leg disc CME L1    0 wing disc CME-W2    2 wing disc ML-DmD8    5 wing disc ML-DmD9    2 wing disc ML-DmD16-c3    2 wing disc ML-DmD21    4 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    18 eye-antennal disc ML-DmD11    3 antennal disc ML-DmD20-c5    10 mixed discs ML-DmD4-c1    1 CNS ML-DmBG1-c1    1 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    0 ovary fGS/OSS    0 ovary OSC    6 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    26 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    12 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult  26 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    12 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    26 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    12 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    26 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    12 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    26 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    12 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult  26 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    12 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    26 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    12 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    2 cold shock, 4-day adult    1 heat shock, 4-day adult    7 Cadmium 50 mM 6 hrs, larvae L3    2 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    9 Cadmium 100 mM 48 hrs, 4-day adult    26 Copper 0.5 mM 12 hrs, larvae L3    3 Copper 15 mM 48 hrs, 4-day adult    11 Zinc 5 mM 12 hrs, larvae L3    1 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    20 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    2 Caffeine 1.5 mg/ml 4 hrs, larvae L3    2 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    14 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    12 Paraquat 10 mM 48 hrs, 4-day adult    7 Rotenone 2 μg 12 hrs, larvae L3    3 Rotenone 8 μg 12 hrs, larvae L3    1 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_23 mE1_20_mRNA_expression_cluster_06
External Data & Images
Linkouts	BDGP expression data • GH26991 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030028 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10965-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for Corp Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele partially lethal - majority die | pupal stage, with Scer\GAL4pnr-MD237 CorpGD7148 Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of Corp Class Mutagen Stocks Known lesion Corpf03996 piggyBac transposase 1 -- Corpf06123 piggyBac transposase 1 -- Corpf07305 piggyBac transposase 0 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of Corp Class Mutagen Stocks Known lesion CorpGD7148 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CorpKK112341 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD7148} NA P{KK112341} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}CG1632EP1167 NA P{EPgy2}CG1632EY03495 NA miscellaneous insertions PBac{WH}Corpf03996 NA PBac{WH}Corpf06123 NA PBac{WH}Corpf07305 NA
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
intrinsic apoptotic signaling pathway in response to DNA damage non-traceable author statement (Yuan, 2002.11.15)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
Corp - AnxB10 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) Corp - CG15084 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Corp - CG15717 anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based (Mintseris et al., 2009.11.23, Guruharsha et al., 2011) Corp - CG7675 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) Corp - CG8525 experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting (Guruharsha et al., 2011, Mintseris et al., 2009.11.23) Corp - Hsp22 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Corp - Hsp23 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Corp - Kap-α3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Corp - Prosα2 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Corp - Prosα4 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Corp - Prosα6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Corp - Prosα7 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Corp - Prosβ1 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Corp - Prosβ3 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Corp - Prosβ5 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Corp - Prosβ6 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Corp - Prosβ7 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Corp - hyd anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) Corp - porin anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions Corp allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 58225 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030028 DroID - A comprehensive database of gene and protein interactions. • FBgn0030028 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31764
Orthologs
OrthoDB Orthologs (12) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6NKCG0 Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6NKCG0)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\Corp     Drosophila simulans   Dsim\GD16122 Y   Drosophila sechellia   Dsec\GM21463 Y   Drosophila erecta   Dere\GG17972 Y   Drosophila yakuba   Dyak\GE17464 Y   Drosophila ananassae   Dana\GF22445 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA10673 Y   Drosophila persimilis   Dper\GL19909 Y   Drosophila willistoni   Dwil\GK16314 Y   Drosophila virilis   Dvir\GJ19025 Y   Drosophila mojavensis   Dmoj\GI15867 Y   Drosophila grimshawi   Dgri\GH12412 Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD16122 Drosophila sechellia Dsec\GM21463 Drosophila erecta Dere\GG17972 Drosophila yakuba Dyak\GE17464 Drosophila ananassae Dana\GF22445 Drosophila pseudoobscura pseudoobscura Dpse\GA10673 Drosophila persimilis Dper\GL19909 Drosophila willistoni Dwil\GK16314 Drosophila virilis Dvir\GJ19025 Drosophila mojavensis Dmoj\GI15867 Drosophila grimshawi Dgri\GH12412
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Harvard	- PBac{WH}Corpf03996 - PBac{WH}Corpf06123
VDRC	v102751 P{KK112341}VIE-260B v16130 w1118; P{GD7148}v16130/CyO
Genomic Clones ( 1 )
	BACR39F18 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 17 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH26991
Other clones	DPiM_GH26991
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	RE25295 RE31625 RE32569
Other clones	Dmel_neb_016200_0665_3037 ESG013b.E21_G02 ESG014b.E21_G09 ESG0112a.B21_B02 ESG0113b.B21.1_H03 ESG0114d.B21_G01 FGM322B05 RP001006398 RP001025880 RP001047933 RP001049421 RP001055517
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030028 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31764
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: Corp CG10965 (FlyBase, 1996-)
Source for database merge of
Additional comments	Source for identity of Corp CG10965 was sequence comparison (date:031206). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132240 NM_001258649 RefSeq (Proteins) • NP_572468 NP_001245578 DDBJ / EMBL / GenBank • AAF46358 AAL28351 AAO62566 AFH07292 AI513963 AW941037 AY060803 AY180959 CZ486584 CZ488771 CZ488772 CZ490122 Entrez Gene - A searchable database of RefSeq genes. • 31764 UniProtKB/TrEMBL • Q9W3G9
Other Crossreferences
	BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GH26991
Linkouts
	BioGRID - A database of protein and genetic interactions • 58225 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030028 DroID - A comprehensive database of gene and protein interactions. • FBgn0030028 DRSC - Results from RNAi screens. • FBgn0030028 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030028 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG10965-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030028 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31764 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31764 modMine - Data generated by the modENCODE project. • FBgn0030028
Synonyms & Secondary IDs ( 5 )
Reported As
Symbol Synonym	CG10965 (Lee et al., 2003, Brodsky et al., 2004, Zhang et al., 2008, Keleman et al., 2009.8.5) Corp (Akdemir et al., 2007) corp (Zhang et al., 2008)
Name Synonym	Companion of reaper (Cao et al., 2007) companion of reaper (Neal et al., 2006, Zhang et al., 2008)
Secondary FlyBase IDs
References ( 21 )
Generate a list of	All references relating to this gene ( 21 )
List References by type	Research paper  ( 6 ) Supplementary material  ( 5 ) Review  ( 1 ) Personal communication to FlyBase  ( 6 ) FlyBase analysis  ( 1 ) DNA/RNA sequence record  ( 1 ) Website  ( 1 )
Recent research papers (0)
	All research papers listed in FlyBase were published before 2011 Show research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2011 Show reviews ...