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Gene Dmel\CG15347

General Information
Symbol	Dmel\CG15347	Species	D. melanogaster
Name		Annotation symbol	CG15347
Feature type	protein_coding_gene	FlyBase ID	FBgn0030040
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	7E11-7E11	Sequence location	X:8,352,527..8,354,931 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG15347 (FBgn0030040). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Domain of unknown function DUF753. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval/adult hindgut, inseminated spermatheca. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult Malpighian tubules, adult heart, larval/adult fat body, virgin spermatheca, adult male reproductive system, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1623761_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG15347. Gene sequence location is X:8352527..8354931.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 7E11-7E11   Limits computationally determined from genome sequence between P{EP}CG1632EP1583 and P{EP}MoeEP1652
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG15347 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Low-frequency RNA-Seq exon junction(s) not annotated. Gene model reviewed during 5.49
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG15347-RA FBtr0071242  NM_132251   923   214 CG15347-RB FBtr0302500  NM_001201633   968   229
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG15347-PA   FBpp0071185   23.4   214   7.84     NP_572479   AAF46374 CG15347-PB   FBpp0291662   25.0   229   8.07     NP_001188562   ADV37644
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Domain of unknown function DUF753 (IPR008472)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF46374   AE014298 ADV37644   AY070650 AAL48121   AY231731   BG639307   BI170122   BI171033   BI214408   BI214422   BI214900   BI215630   BI230370   BI231661   BI231999   BI232878   BI236633   BI236811   BI238896   BI240463   BI243673   BI366343   BI366547   BI367683   BI368199   BI372876   BI565936   BI580321   BI583505   BI590000   BI640010   BT126089   CO155873   CO189678   CO264224   CO266745   CO266843   CO268699   CO307289   CO318948   CO319599   CO323670   CO328300   CO337181   EC060861   EC061628   EC063552   EC069405   EC071111   EC201730   EC217277   EC227649   EC244970   EC254200   EC263919   ES688491   ES690765   EV586377   EV589750   GH944020   GH946486   GH949776   GH950319   GH952070   GH962083   GH969066   GH971223   GH974132   GH979871   GH981264   GH984634
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9W3F3
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 11 -- 12   amnioserosa   (Fisher et al., 2012) yolk nucleus   (Fisher et al., 2012) embryonic stage 13 -- 16   amnioserosa   (Fisher et al., 2012) embryonic midgut chamber   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) gastric caecum   (Fisher et al., 2012) yolk nucleus   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at high levels in the following post-embryonic organs or tissues: larval/adult midgut, larval/adult hindgut, inseminated spermatheca. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult Malpighian tubules, adult heart, larval/adult fat body, virgin spermatheca, adult male reproductive system, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2.9 Larval Midgut    2810.6 Larval Hindgut    676.1 Larval Malpighian Tubules    335.9 Larval Fat Body    138.2 Larval Salivary Gland    7.4 Larval Trachea    12.15 Larval Carcass    9.45 Adult Head    79.4 Adult Eye    15.475 Adult Brain    3.1 Adult Thoracic-Abdominal Ganglion    3.7 Adult Crop    9.3 Adult Midgut    3668.3 Adult Hindgut    878.7 Adult Malpighian Tubules    434.3 Adult Fat Body    338.5 Adult Salivary Gland    4.4 Adult Heart    301.3 Adult VirginFemale Spermatheca    426.2 Adult InseminatedFemale Spermatheca    524.8 Adult Ovary    62.6 Adult Testis    160.1 Adult Male Accessory Gland    170.8 Adult Carcass    160.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    2.9 Larval Midgut  (2810.6) Larval Hindgut  (676.1) Larval Malpighian Tubules    335.9 Larval Fat Body    138.2 Larval Salivary Gland    7.4 Larval Trachea    12.15 Larval Carcass    9.45 Adult Head    79.4 Adult Eye    15.475 Adult Brain    3.1 Adult Thoracic-Abdominal Ganglion    3.7 Adult Crop    9.3 Adult Midgut  (3668.3) Adult Hindgut  (878.7) Adult Malpighian Tubules    434.3 Adult Fat Body    338.5 Adult Salivary Gland    4.4 Adult Heart    301.3 Adult VirginFemale Spermatheca    426.2 Adult InseminatedFemale Spermatheca  524.8 Adult Ovary    62.6 Adult Testis    160.1 Adult Male Accessory Gland    170.8 Adult Carcass    160.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    2.9 Larval Midgut  (2810.6) Larval Hindgut    676.1 Larval Malpighian Tubules    335.9 Larval Fat Body    138.2 Larval Salivary Gland    7.4 Larval Trachea    12.15 Larval Carcass    9.45 Adult Head    79.4 Adult Eye    15.475 Adult Brain    3.1 Adult Thoracic-Abdominal Ganglion    3.7 Adult Crop    9.3 Adult Midgut  (3668.3) Adult Hindgut    878.7 Adult Malpighian Tubules    434.3 Adult Fat Body    338.5 Adult Salivary Gland    4.4 Adult Heart    301.3 Adult VirginFemale Spermatheca    426.2 Adult InseminatedFemale Spermatheca    524.8 Adult Ovary    62.6 Adult Testis    160.1 Adult Male Accessory Gland    170.8 Adult Carcass    160.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2.9 Larval Midgut    2810.6 Larval Hindgut    676.1 Larval Malpighian Tubules    335.9 Larval Fat Body    138.2 Larval Salivary Gland    7.4 Larval Trachea    12.15 Larval Carcass    9.45 Adult Head    79.4 Adult Eye    15.475 Adult Brain    3.1 Adult Thoracic-Abdominal Ganglion    3.7 Adult Crop    9.3 Adult Midgut    3668.3 Adult Hindgut    878.7 Adult Malpighian Tubules    434.3 Adult Fat Body    338.5 Adult Salivary Gland    4.4 Adult Heart    301.3 Adult VirginFemale Spermatheca    426.2 Adult InseminatedFemale Spermatheca    524.8 Adult Ovary    62.6 Adult Testis    160.1 Adult Male Accessory Gland    170.8 Adult Carcass    160.1 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    2.9 Larval Midgut    2810.6 Larval Hindgut    676.1 Larval Malpighian Tubules    335.9 Larval Fat Body    138.2 Larval Salivary Gland    7.4 Larval Trachea    12.15 Larval Carcass    9.45 Adult Head    79.4 Adult Eye    15.475 Adult Brain    3.1 Adult Thoracic-Abdominal Ganglion    3.7 Adult Crop    9.3 Adult Midgut    3668.3 Adult Hindgut    878.7 Adult Malpighian Tubules    434.3 Adult Fat Body    338.5 Adult Salivary Gland    4.4 Adult Heart    301.3 Adult VirginFemale Spermatheca    426.2 Adult InseminatedFemale Spermatheca    524.8 Adult Ovary    62.6 Adult Testis    160.1 Adult Male Accessory Gland    170.8 Adult Carcass    160.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    2.9 Larval Midgut  (2810.6) Larval Hindgut  676.1 Larval Malpighian Tubules    335.9 Larval Fat Body    138.2 Larval Salivary Gland    7.4 Larval Trachea    12.15 Larval Carcass    9.45 Adult Head    79.4 Adult Eye    15.475 Adult Brain    3.1 Adult Thoracic-Abdominal Ganglion    3.7 Adult Crop    9.3 Adult Midgut  (3668.3) Adult Hindgut  (878.7) Adult Malpighian Tubules    434.3 Adult Fat Body    338.5 Adult Salivary Gland    4.4 Adult Heart    301.3 Adult VirginFemale Spermatheca    426.2 Adult InseminatedFemale Spermatheca  524.8 Adult Ovary    62.6 Adult Testis    160.1 Adult Male Accessory Gland    170.8 Adult Carcass    160.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    2.9 Larval Midgut  (2810.6) Larval Hindgut    676.1 Larval Malpighian Tubules    335.9 Larval Fat Body    138.2 Larval Salivary Gland    7.4 Larval Trachea    12.15 Larval Carcass    9.45 Adult Head    79.4 Adult Eye    15.475 Adult Brain    3.1 Adult Thoracic-Abdominal Ganglion    3.7 Adult Crop    9.3 Adult Midgut  (3668.3) Adult Hindgut    878.7 Adult Malpighian Tubules    434.3 Adult Fat Body    338.5 Adult Salivary Gland    4.4 Adult Heart    301.3 Adult VirginFemale Spermatheca    426.2 Adult InseminatedFemale Spermatheca    524.8 Adult Ovary    62.6 Adult Testis    160.1 Adult Male Accessory Gland    170.8 Adult Carcass    160.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    2.9 Larval Midgut    2810.6 Larval Hindgut    676.1 Larval Malpighian Tubules    335.9 Larval Fat Body    138.2 Larval Salivary Gland    7.4 Larval Trachea    12.15 Larval Carcass    9.45 Adult Head    79.4 Adult Eye    15.475 Adult Brain    3.1 Adult Thoracic-Abdominal Ganglion    3.7 Adult Crop    9.3 Adult Midgut    3668.3 Adult Hindgut    878.7 Adult Malpighian Tubules    434.3 Adult Fat Body    338.5 Adult Salivary Gland    4.4 Adult Heart    301.3 Adult VirginFemale Spermatheca    426.2 Adult InseminatedFemale Spermatheca    524.8 Adult Ovary    62.6 Adult Testis    160.1 Adult Male Accessory Gland    170.8 Adult Carcass    160.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    79.4   NA  Eye    15.475   NA  Brain    3.1   2.9  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    3.7   NA  Crop    9.3   2810.6  Midgut    3668.3   676.1  Hindgut    878.7   335.9  Malpighian Tubules    434.3   138.2  Fat Body    338.5   7.4  Salivary Gland    4.4   NA  Heart    301.3   no informative data  Trachea    NA   NA  VirginFemale Spermatheca    426.2   NA  InseminatedFemale Spermatheca    524.8   NA  Ovary    62.6   NA  Testis    160.1   NA  Male Accessory Gland    170.8   9.45  Carcass    160.1 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    24 central nervous system, larvae L3    0 central nervous system, pupae P8    1 head, virgin 1-day female    3 head, virgin 4-day female    1 head, virgin 20-day female    8 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    6 head, mated 1-day male    2 head, mated 4-day male    3 head, mated 20-day male    10 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    162 digestive system, 1-day adult    290 digestive system, 4-day adult    151 digestive system, 20-day adult    278 fat body, larvae L3 wandering    2 fat body, white prepupae    4 fat body, pupae P8    34 carcass, larvae L3 wandering    1 carcass, 1-day adult    6 carcass, 4-day adult    4 carcass, 20-day adult    12 ovary, virgin 4-day female    5 ovary, mated 4-day female    7 testis, mated 4-day male    23 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    24 central nervous system, larvae L3    0 central nervous system, pupae P8    1 head, virgin 1-day female    3 head, virgin 4-day female    1 head, virgin 20-day female    8 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    6 head, mated 1-day male    2 head, mated 4-day male    3 head, mated 20-day male    10 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    1 digestive system, larvae L3 wandering  (162) digestive system, 1-day adult  (290) digestive system, 4-day adult  (151) digestive system, 20-day adult  (278) fat body, larvae L3 wandering    2 fat body, white prepupae    4 fat body, pupae P8  (34) carcass, larvae L3 wandering    1 carcass, 1-day adult    6 carcass, 4-day adult    4 carcass, 20-day adult    12 ovary, virgin 4-day female    5 ovary, mated 4-day female    7 testis, mated 4-day male    23 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    24 central nervous system, larvae L3    0 central nervous system, pupae P8    1 head, virgin 1-day female    3 head, virgin 4-day female    1 head, virgin 20-day female    8 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    6 head, mated 1-day male    2 head, mated 4-day male    3 head, mated 20-day male    10 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    1 digestive system, larvae L3 wandering  (162) digestive system, 1-day adult  (290) digestive system, 4-day adult  (151) digestive system, 20-day adult  (278) fat body, larvae L3 wandering    2 fat body, white prepupae    4 fat body, pupae P8    34 carcass, larvae L3 wandering    1 carcass, 1-day adult    6 carcass, 4-day adult    4 carcass, 20-day adult    12 ovary, virgin 4-day female    5 ovary, mated 4-day female    7 testis, mated 4-day male    23 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    24 central nervous system, larvae L3    0 central nervous system, pupae P8    1 head, virgin 1-day female    3 head, virgin 4-day female    1 head, virgin 20-day female    8 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    6 head, mated 1-day male    2 head, mated 4-day male    3 head, mated 20-day male    10 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    162 digestive system, 1-day adult    290 digestive system, 4-day adult    151 digestive system, 20-day adult    278 fat body, larvae L3 wandering    2 fat body, white prepupae    4 fat body, pupae P8    34 carcass, larvae L3 wandering    1 carcass, 1-day adult    6 carcass, 4-day adult    4 carcass, 20-day adult    12 ovary, virgin 4-day female    5 ovary, mated 4-day female    7 testis, mated 4-day male    23 accessory gland, mated 4-day male    15 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    24 central nervous system, larvae L3    0 central nervous system, pupae P8    1 head, virgin 1-day female    3 head, virgin 4-day female    1 head, virgin 20-day female    8 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    6 head, mated 1-day male    2 head, mated 4-day male    3 head, mated 20-day male    10 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    162 digestive system, 1-day adult    290 digestive system, 4-day adult    151 digestive system, 20-day adult    278 fat body, larvae L3 wandering    2 fat body, white prepupae    4 fat body, pupae P8    34 carcass, larvae L3 wandering    1 carcass, 1-day adult    6 carcass, 4-day adult    4 carcass, 20-day adult    12 ovary, virgin 4-day female    5 ovary, mated 4-day female    7 testis, mated 4-day male    23 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    24 central nervous system, larvae L3    0 central nervous system, pupae P8    1 head, virgin 1-day female    3 head, virgin 4-day female    1 head, virgin 20-day female    8 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    6 head, mated 1-day male    2 head, mated 4-day male    3 head, mated 20-day male    10 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    1 digestive system, larvae L3 wandering  (162) digestive system, 1-day adult  (290) digestive system, 4-day adult  (151) digestive system, 20-day adult  (278) fat body, larvae L3 wandering    2 fat body, white prepupae    4 fat body, pupae P8  (34) carcass, larvae L3 wandering    1 carcass, 1-day adult    6 carcass, 4-day adult    4 carcass, 20-day adult    12 ovary, virgin 4-day female    5 ovary, mated 4-day female    7 testis, mated 4-day male    23 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    24 central nervous system, larvae L3    0 central nervous system, pupae P8    1 head, virgin 1-day female    3 head, virgin 4-day female    1 head, virgin 20-day female    8 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    6 head, mated 1-day male    2 head, mated 4-day male    3 head, mated 20-day male    10 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    1 digestive system, larvae L3 wandering  (162) digestive system, 1-day adult  (290) digestive system, 4-day adult  (151) digestive system, 20-day adult  (278) fat body, larvae L3 wandering    2 fat body, white prepupae    4 fat body, pupae P8    34 carcass, larvae L3 wandering    1 carcass, 1-day adult    6 carcass, 4-day adult    4 carcass, 20-day adult    12 ovary, virgin 4-day female    5 ovary, mated 4-day female    7 testis, mated 4-day male    23 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    24 central nervous system, larvae L3    0 central nervous system, pupae P8    1 head, virgin 1-day female    3 head, virgin 4-day female    1 head, virgin 20-day female    8 head, mated 1-day female    1 head, mated 4-day female    1 head, mated 20-day female    6 head, mated 1-day male    2 head, mated 4-day male    3 head, mated 20-day male    10 salivary gland, larvae L3 wandering    2 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    162 digestive system, 1-day adult    290 digestive system, 4-day adult    151 digestive system, 20-day adult    278 fat body, larvae L3 wandering    2 fat body, white prepupae    4 fat body, pupae P8    34 carcass, larvae L3 wandering    1 carcass, 1-day adult    6 carcass, 4-day adult    4 carcass, 20-day adult    12 ovary, virgin 4-day female    5 ovary, mated 4-day female    7 testis, mated 4-day male    23 accessory gland, mated 4-day male    15 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of low expression. Peak expression observed within 06-24 hour embryonic stages, at stages throughout the larval period, during early pupal stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    2 embryo 04-06hr    2 embryo 06-08hr    15 embryo 08-10hr    37 embryo 10-12hr    180 embryo 12-14hr    185 embryo 14-16hr    356 embryo 16-18hr    310 embryo 18-20hr    282 embryo 20-22hr    328 embryo 22-24hr    302 larva L1    292 larva L2    250 larva L3 12hr old    173 larva L3 puffstage 1-2    180 larva L3 puffstage 3-6    95 larva L3 puffstage 7-9    71 white prepupae new    69 white prepupae 12hr    185 white prepupae 24hr    96 pupae 2d postWPP    63 pupae 3d postWPP    30 pupae 4d postWPP    80 adult male 01day    122 adult male 05day    135 adult male 30day    154 adult female 01day    193 adult female 05day    74 adult female 30day    105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    2 embryo 04-06hr    2 embryo 06-08hr    15 embryo 08-10hr  (37) embryo 10-12hr  (180) embryo 12-14hr  (185) embryo 14-16hr  (356) embryo 16-18hr  (310) embryo 18-20hr  (282) embryo 20-22hr  (328) embryo 22-24hr  (302) larva L1  (292) larva L2  (250) larva L3 12hr old  (173) larva L3 puffstage 1-2  (180) larva L3 puffstage 3-6  (95) larva L3 puffstage 7-9  (71) white prepupae new  (69) white prepupae 12hr  (185) white prepupae 24hr  (96) pupae 2d postWPP  (63) pupae 3d postWPP  (30) pupae 4d postWPP  (80) adult male 01day  (122) adult male 05day  (135) adult male 30day  (154) adult female 01day  (193) adult female 05day  (74) adult female 30day  (105) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    2 embryo 04-06hr    2 embryo 06-08hr    15 embryo 08-10hr    37 embryo 10-12hr  (180) embryo 12-14hr  (185) embryo 14-16hr  (356) embryo 16-18hr  (310) embryo 18-20hr  (282) embryo 20-22hr  (328) embryo 22-24hr  (302) larva L1  (292) larva L2  (250) larva L3 12hr old  (173) larva L3 puffstage 1-2  (180) larva L3 puffstage 3-6    95 larva L3 puffstage 7-9    71 white prepupae new    69 white prepupae 12hr  (185) white prepupae 24hr    96 pupae 2d postWPP    63 pupae 3d postWPP    30 pupae 4d postWPP    80 adult male 01day  (122) adult male 05day  (135) adult male 30day  (154) adult female 01day  (193) adult female 05day    74 adult female 30day  105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    2 embryo 04-06hr    2 embryo 06-08hr    15 embryo 08-10hr    37 embryo 10-12hr    180 embryo 12-14hr    185 embryo 14-16hr    356 embryo 16-18hr    310 embryo 18-20hr    282 embryo 20-22hr    328 embryo 22-24hr    302 larva L1    292 larva L2    250 larva L3 12hr old    173 larva L3 puffstage 1-2    180 larva L3 puffstage 3-6    95 larva L3 puffstage 7-9    71 white prepupae new    69 white prepupae 12hr    185 white prepupae 24hr    96 pupae 2d postWPP    63 pupae 3d postWPP    30 pupae 4d postWPP    80 adult male 01day    122 adult male 05day    135 adult male 30day    154 adult female 01day    193 adult female 05day    74 adult female 30day    105 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    2 embryo 04-06hr    2 embryo 06-08hr    15 embryo 08-10hr    37 embryo 10-12hr    180 embryo 12-14hr    185 embryo 14-16hr    356 embryo 16-18hr    310 embryo 18-20hr    282 embryo 20-22hr    328 embryo 22-24hr    302 larva L1    292 larva L2    250 larva L3 12hr old    173 larva L3 puffstage 1-2    180 larva L3 puffstage 3-6    95 larva L3 puffstage 7-9    71 white prepupae new    69 white prepupae 12hr    185 white prepupae 24hr    96 pupae 2d postWPP    63 pupae 3d postWPP    30 pupae 4d postWPP    80 adult male 01day    122 adult male 05day    135 adult male 30day    154 adult female 01day    193 adult female 05day    74 adult female 30day    105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    2 embryo 04-06hr    2 embryo 06-08hr    15 embryo 08-10hr  (37) embryo 10-12hr  (180) embryo 12-14hr  (185) embryo 14-16hr  (356) embryo 16-18hr  (310) embryo 18-20hr  (282) embryo 20-22hr  (328) embryo 22-24hr  (302) larva L1  (292) larva L2  (250) larva L3 12hr old  (173) larva L3 puffstage 1-2  (180) larva L3 puffstage 3-6  (95) larva L3 puffstage 7-9  (71) white prepupae new  (69) white prepupae 12hr  (185) white prepupae 24hr  (96) pupae 2d postWPP  (63) pupae 3d postWPP  30 pupae 4d postWPP  (80) adult male 01day  (122) adult male 05day  (135) adult male 30day  (154) adult female 01day  (193) adult female 05day  (74) adult female 30day  (105) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    2 embryo 04-06hr    2 embryo 06-08hr    15 embryo 08-10hr    37 embryo 10-12hr  (180) embryo 12-14hr  (185) embryo 14-16hr  (356) embryo 16-18hr  (310) embryo 18-20hr  (282) embryo 20-22hr  (328) embryo 22-24hr  (302) larva L1  (292) larva L2  (250) larva L3 12hr old  (173) larva L3 puffstage 1-2  (180) larva L3 puffstage 3-6    95 larva L3 puffstage 7-9    71 white prepupae new    69 white prepupae 12hr  (185) white prepupae 24hr    96 pupae 2d postWPP    63 pupae 3d postWPP    30 pupae 4d postWPP    80 adult male 01day  122 adult male 05day  135 adult male 30day  (154) adult female 01day  (193) adult female 05day    74 adult female 30day  105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2 embryo 02-04hr    2 embryo 04-06hr    2 embryo 06-08hr    15 embryo 08-10hr    37 embryo 10-12hr    180 embryo 12-14hr    185 embryo 14-16hr    356 embryo 16-18hr    310 embryo 18-20hr    282 embryo 20-22hr    328 embryo 22-24hr    302 larva L1    292 larva L2    250 larva L3 12hr old    173 larva L3 puffstage 1-2    180 larva L3 puffstage 3-6    95 larva L3 puffstage 7-9    71 white prepupae new    69 white prepupae 12hr    185 white prepupae 24hr    96 pupae 2d postWPP    63 pupae 3d postWPP    30 pupae 4d postWPP    80 adult male 01day    122 adult male 05day    135 adult male 30day    154 adult female 01day    193 adult female 05day    74 adult female 30day    105 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    3 Schneider line 2 Sg4    33 embryonic 1182-4H    23 embryonic GM2    279 embryonic Kc167    92 embryonic S1    125 embryonic S3    0 leg disc CME L1    40 wing disc CME-W2    196 wing disc ML-DmD8    7 wing disc ML-DmD9    21 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    17 CNS ML-DmBG2-c2    67 tumorous blood cells mbn2    30 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    3 Schneider line 2 Sg4  (33) embryonic 1182-4H    23 embryonic GM2  (279) embryonic Kc167  (92) embryonic S1  (125) embryonic S3    0 leg disc CME L1  (40) wing disc CME-W2  (196) wing disc ML-DmD8    7 wing disc ML-DmD9    21 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    17 CNS ML-DmBG2-c2  (67) tumorous blood cells mbn2  (30) ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    3 Schneider line 2 Sg4    33 embryonic 1182-4H    23 embryonic GM2  (279) embryonic Kc167    92 embryonic S1  (125) embryonic S3    0 leg disc CME L1    40 wing disc CME-W2  (196) wing disc ML-DmD8    7 wing disc ML-DmD9    21 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    17 CNS ML-DmBG2-c2    67 tumorous blood cells mbn2    30 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    3 Schneider line 2 Sg4    33 embryonic 1182-4H    23 embryonic GM2    279 embryonic Kc167    92 embryonic S1    125 embryonic S3    0 leg disc CME L1    40 wing disc CME-W2    196 wing disc ML-DmD8    7 wing disc ML-DmD9    21 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    17 CNS ML-DmBG2-c2    67 tumorous blood cells mbn2    30 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    3 Schneider line 2 Sg4    33 embryonic 1182-4H    23 embryonic GM2    279 embryonic Kc167    92 embryonic S1    125 embryonic S3    0 leg disc CME L1    40 wing disc CME-W2    196 wing disc ML-DmD8    7 wing disc ML-DmD9    21 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    17 CNS ML-DmBG2-c2    67 tumorous blood cells mbn2    30 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    3 Schneider line 2 Sg4  (33) embryonic 1182-4H    23 embryonic GM2  (279) embryonic Kc167  (92) embryonic S1  (125) embryonic S3    0 leg disc CME L1  (40) wing disc CME-W2  (196) wing disc ML-DmD8    7 wing disc ML-DmD9    21 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    17 CNS ML-DmBG2-c2  (67) tumorous blood cells mbn2  30 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    3 Schneider line 2 Sg4    33 embryonic 1182-4H    23 embryonic GM2  (279) embryonic Kc167    92 embryonic S1  125 embryonic S3    0 leg disc CME L1    40 wing disc CME-W2  (196) wing disc ML-DmD8    7 wing disc ML-DmD9    21 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    17 CNS ML-DmBG2-c2    67 tumorous blood cells mbn2    30 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    3 Schneider line 2 Sg4    33 embryonic 1182-4H    23 embryonic GM2    279 embryonic Kc167    92 embryonic S1    125 embryonic S3    0 leg disc CME L1    40 wing disc CME-W2    196 wing disc ML-DmD8    7 wing disc ML-DmD9    21 wing disc ML-DmD16-c3    8 wing disc ML-DmD21    1 wing disc ML-DmD32    1 haltere disc ML-DmD17-c3    0 eye-antennal disc ML-DmD11    19 antennal disc ML-DmD20-c5    5 mixed discs ML-DmD4-c1    20 CNS ML-DmBG1-c1    17 CNS ML-DmBG2-c2    67 tumorous blood cells mbn2    30 ovary fGS/OSS    0 ovary OSC    0 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    31 cold shock, 4-day adult    23 heat shock, 4-day adult    58 Cadmium 50 mM 6 hrs, larvae L3    131 Cadmium 50 mM 12 hrs, larvae L3    67 Cadmium 50 mM 48 hrs, 4-day adult    92 Cadmium 100 mM 48 hrs, 4-day adult    53 Copper 0.5 mM 12 hrs, larvae L3    67 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    53 Zinc 4.5 mM 48 hrs, 4-day adult    39 Ethanol 2.5% 3 hrs, larvae L3    68 Ethanol 5% 3 hrs, larvae L3    204 Ethanol 10% 3 hrs, larvae L3    177 Caffeine 1.5 mg/ml 4 hrs, larvae L3    119 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    27 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    48 Paraquat 10 mM 48 hrs, 4-day adult    75 Rotenone 2 μg 12 hrs, larvae L3    224 Rotenone 8 μg 12 hrs, larvae L3    270 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (31) cold shock, 4-day adult    23 heat shock, 4-day adult  (58) Cadmium 50 mM 6 hrs, larvae L3  (131) Cadmium 50 mM 12 hrs, larvae L3  (67) Cadmium 50 mM 48 hrs, 4-day adult  (92) Cadmium 100 mM 48 hrs, 4-day adult  (53) Copper 0.5 mM 12 hrs, larvae L3  (67) Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3  (53) Zinc 4.5 mM 48 hrs, 4-day adult  (39) Ethanol 2.5% 3 hrs, larvae L3  (68) Ethanol 5% 3 hrs, larvae L3  (204) Ethanol 10% 3 hrs, larvae L3  (177) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (119) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (27) Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult  (48) Paraquat 10 mM 48 hrs, 4-day adult  (75) Rotenone 2 μg 12 hrs, larvae L3  (224) Rotenone 8 μg 12 hrs, larvae L3  (270) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    31 cold shock, 4-day adult    23 heat shock, 4-day adult    58 Cadmium 50 mM 6 hrs, larvae L3  (131) Cadmium 50 mM 12 hrs, larvae L3    67 Cadmium 50 mM 48 hrs, 4-day adult    92 Cadmium 100 mM 48 hrs, 4-day adult    53 Copper 0.5 mM 12 hrs, larvae L3    67 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    53 Zinc 4.5 mM 48 hrs, 4-day adult    39 Ethanol 2.5% 3 hrs, larvae L3    68 Ethanol 5% 3 hrs, larvae L3  (204) Ethanol 10% 3 hrs, larvae L3  (177) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (119) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    27 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    48 Paraquat 10 mM 48 hrs, 4-day adult    75 Rotenone 2 μg 12 hrs, larvae L3  (224) Rotenone 8 μg 12 hrs, larvae L3  (270) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    31 cold shock, 4-day adult    23 heat shock, 4-day adult    58 Cadmium 50 mM 6 hrs, larvae L3    131 Cadmium 50 mM 12 hrs, larvae L3    67 Cadmium 50 mM 48 hrs, 4-day adult    92 Cadmium 100 mM 48 hrs, 4-day adult    53 Copper 0.5 mM 12 hrs, larvae L3    67 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    53 Zinc 4.5 mM 48 hrs, 4-day adult    39 Ethanol 2.5% 3 hrs, larvae L3    68 Ethanol 5% 3 hrs, larvae L3    204 Ethanol 10% 3 hrs, larvae L3    177 Caffeine 1.5 mg/ml 4 hrs, larvae L3    119 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    27 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    48 Paraquat 10 mM 48 hrs, 4-day adult    75 Rotenone 2 μg 12 hrs, larvae L3    224 Rotenone 8 μg 12 hrs, larvae L3    270 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    31 cold shock, 4-day adult    23 heat shock, 4-day adult    58 Cadmium 50 mM 6 hrs, larvae L3    131 Cadmium 50 mM 12 hrs, larvae L3    67 Cadmium 50 mM 48 hrs, 4-day adult    92 Cadmium 100 mM 48 hrs, 4-day adult    53 Copper 0.5 mM 12 hrs, larvae L3    67 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    53 Zinc 4.5 mM 48 hrs, 4-day adult    39 Ethanol 2.5% 3 hrs, larvae L3    68 Ethanol 5% 3 hrs, larvae L3    204 Ethanol 10% 3 hrs, larvae L3    177 Caffeine 1.5 mg/ml 4 hrs, larvae L3    119 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    27 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    48 Paraquat 10 mM 48 hrs, 4-day adult    75 Rotenone 2 μg 12 hrs, larvae L3    224 Rotenone 8 μg 12 hrs, larvae L3    270 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  31 cold shock, 4-day adult    23 heat shock, 4-day adult  (58) Cadmium 50 mM 6 hrs, larvae L3  (131) Cadmium 50 mM 12 hrs, larvae L3  (67) Cadmium 50 mM 48 hrs, 4-day adult  (92) Cadmium 100 mM 48 hrs, 4-day adult  (53) Copper 0.5 mM 12 hrs, larvae L3  (67) Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3  (53) Zinc 4.5 mM 48 hrs, 4-day adult  (39) Ethanol 2.5% 3 hrs, larvae L3  (68) Ethanol 5% 3 hrs, larvae L3  (204) Ethanol 10% 3 hrs, larvae L3  (177) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (119) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  27 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult  (48) Paraquat 10 mM 48 hrs, 4-day adult  (75) Rotenone 2 μg 12 hrs, larvae L3  (224) Rotenone 8 μg 12 hrs, larvae L3  (270) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    31 cold shock, 4-day adult    23 heat shock, 4-day adult    58 Cadmium 50 mM 6 hrs, larvae L3  131 Cadmium 50 mM 12 hrs, larvae L3    67 Cadmium 50 mM 48 hrs, 4-day adult    92 Cadmium 100 mM 48 hrs, 4-day adult    53 Copper 0.5 mM 12 hrs, larvae L3    67 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    53 Zinc 4.5 mM 48 hrs, 4-day adult    39 Ethanol 2.5% 3 hrs, larvae L3    68 Ethanol 5% 3 hrs, larvae L3  (204) Ethanol 10% 3 hrs, larvae L3  (177) Caffeine 1.5 mg/ml 4 hrs, larvae L3  119 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    27 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    48 Paraquat 10 mM 48 hrs, 4-day adult    75 Rotenone 2 μg 12 hrs, larvae L3  (224) Rotenone 8 μg 12 hrs, larvae L3  (270) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    31 cold shock, 4-day adult    23 heat shock, 4-day adult    58 Cadmium 50 mM 6 hrs, larvae L3    131 Cadmium 50 mM 12 hrs, larvae L3    67 Cadmium 50 mM 48 hrs, 4-day adult    92 Cadmium 100 mM 48 hrs, 4-day adult    53 Copper 0.5 mM 12 hrs, larvae L3    67 Copper 15 mM 48 hrs, 4-day adult    18 Zinc 5 mM 12 hrs, larvae L3    53 Zinc 4.5 mM 48 hrs, 4-day adult    39 Ethanol 2.5% 3 hrs, larvae L3    68 Ethanol 5% 3 hrs, larvae L3    204 Ethanol 10% 3 hrs, larvae L3    177 Caffeine 1.5 mg/ml 4 hrs, larvae L3    119 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    27 Caffeine 25 mg/ml 48 hrs, 4-day adult    24 Paraquat 5 mM 48 hrs, 4-day adult    48 Paraquat 10 mM 48 hrs, 4-day adult    75 Rotenone 2 μg 12 hrs, larvae L3    224 Rotenone 8 μg 12 hrs, larvae L3    270 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_18
External Data & Images
Linkouts	BDGP expression data • LP18071 RH03540 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030040 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG15347-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG15347 Stages(s) 1-3 Stages(s) 7-8 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG15347GD8987 Phenotype manifest in Allele
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG15347 Class Mutagen Stocks Known lesion CG15347MB04140 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG15347 Class Mutagen Stocks Known lesion CG15347GD8987 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG15347KK110908 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG15347NIG.15347R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD8987} NA P{KK110908} NA P{NIG.15347R} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap binary system Mi{ET1}CG15347MB04140 No
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG15347 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 58238 DroID - A comprehensive database of gene and protein interactions. • FBgn0030040 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31779
Orthologs
OrthoDB Orthologs (12) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6W3T7H Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6W3T7H)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG15347     Drosophila simulans   Dsim\GD16112 Y   Drosophila sechellia   Dsec\GM21334 Y   Drosophila erecta   Dere\GG19047 Y   Drosophila yakuba   Dyak\GE17452 Y   Drosophila ananassae   Dana\GF22583 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA13659 Y   Drosophila persimilis   Dper\GL20247 Y   Drosophila willistoni   Dwil\GK19986 Y   Drosophila virilis   Dvir\GJ18623 Y   Drosophila mojavensis   Dmoj\GI15766 Y   Drosophila grimshawi   Dgri\GH12232 Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD16112 Drosophila sechellia Dsec\GM21334 Drosophila erecta Dere\GG19047 Drosophila yakuba Dyak\GE17452 Drosophila ananassae Dana\GF22583 Drosophila pseudoobscura pseudoobscura Dpse\GA13659 Drosophila persimilis Dper\GL20247 Drosophila willistoni Dwil\GK19986 Drosophila virilis Dvir\GJ18623 Drosophila mojavensis Dmoj\GI15766 Drosophila grimshawi Dgri\GH12232
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	24568 w1118 Mi{ET1}CG15347MB04140
VDRC	v107479 P{KK110908}VIE-260B v32574 w1118; P{GD8987}v32574/TM3
Genomic Clones ( 1 )
	BACR17J10 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 67 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LP18071 RH03540
Other clones	yak-em_CG15347
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LP03413 RE10168 RE11480 RE12684 RE20203 RE20223 RE21049 RE22204 RE22965 RE25189 RE29024 RE32712 RE32931 RE37313 RE41380 RE42009 RE51858 RE52110 RE53483 RE54126 RE60068 RE74496 RH22133 RH34769 SD22760
Other clones	29556 36753 37016 70835 80797 181150 214477.20 525660 CK01.6A.G4 CK01.55C.G8 CK01.120D.H7 Dmel_neb_008274_0392_3576 Dmel_neb_014127_0144_2092 EK044860 EK092432 EK138157 EK147420 EK147736 EK191102 EK254304 EK275507 EK279308 EN06911 EN14003 EP08929 RC0-DA0001-120700-011-A04 RC0-DA0001-130700-116-D12 RP004148985 RP004170036 RP004179474 RP004196134 RP004219442 RP004232821 RP004244190 RP004247127 RP004369762 RP004415815 RP004447433 RP004529212
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030040 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31779
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132251 NM_001201633 RefSeq (Proteins) • NP_572479 NP_001188562 DDBJ / EMBL / GenBank • AAF46374 AAL48121 ADV37644 AY070650 BI590000 Entrez Gene - A searchable database of RefSeq genes. • 31779 UniProtKB/TrEMBL • Q9W3F3
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Domain of unknown function DUF753 (IPR008472) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • LP18071 RH03540
Linkouts
	BioGRID - A database of protein and genetic interactions • 58238 DroID - A comprehensive database of gene and protein interactions. • FBgn0030040 DRSC - Results from RNAi screens. • FBgn0030040 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030040 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG15347-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030040 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31779 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31779 modMine - Data generated by the modENCODE project. • FBgn0030040
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG15347 (Rehwinkel et al., 2006, Bhutkar et al., 2008, Lebo et al., 2009, Lipatov et al., 2005, Hijazi et al., 2009, Qin et al., 2005, Keleman et al., 2009.8.5, Nilton et al., 2010, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym
Secondary FlyBase IDs
References ( 19 )
Research paper	Baycin-Hizal et al., 2011, J. Proteome Res. 10(6): 2777--2784 GlycoFly: A Database of Drosophila N-linked Glycoproteins Identified Using SPEG-MS Techniques. [FBrf0213834] Nilton et al., 2010, Development 137(14): 2427--2437 Crooked, coiled and crimpled are three Ly6-like proteins required for proper localization of septate junction components. [FBrf0211147] Hijazi et al., 2009, Development 136(13): 2199--2209 boudin is required for septate junction organisation in Drosophila and codes for a diffusible protein of the Ly6 superfamily. [FBrf0208255] Lebo et al., 2009, BMC Genomics 10: 80 Somatic, germline and sex hierarchy regulated gene expression during Drosophila metamorphosis. [FBrf0207472] Bhutkar et al., 2008, Genetics 179(3): 1657--1680 Chromosomal rearrangement inferred from comparisons of 12 Drosophila genomes. [FBrf0205803] Rehwinkel et al., 2006, Mol. Cell. Biol. 26(8): 2965--2975 Genome-wide analysis of mRNAs regulated by Drosha and Argonaute proteins in Drosophila melanogaster. [FBrf0191204] Lipatov et al., 2005, BMC Biol. 3: 24 Paucity of chimeric gene-transposable element transcripts in the Drosophila melanogaster genome. [FBrf0189752] Qin et al., 2005, Insect Mol. Biol. 14(6): 607--613 Cold hardening and transcriptional change in Drosophila melanogaster. [FBrf0190857] Asha et al., 2003, Genetics 163(1): 203--215 Analysis of ras-induced overproliferation in Drosophila hemocytes. [FBrf0155813]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Bellen, 2007.10.9, batch761.xml batch761.xml [FBrf0200260] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]