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FB2021_03, released June 15, 2021

Gene: Dmel\CAH3

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General Information
Symbol
Dmel\CAH3
Species
D. melanogaster
Name
Carbonic anhydrase 3
Annotation Symbol
CG11284
Feature Type
protein_coding_gene
FlyBase ID
FBgn0030056
Gene Model Status
Current
Stock Availability
5 publicly available
Enzyme Name (EC)
Carbonic anhydrase (4.2.1.1)
Gene Summary
Contribute a Gene Snapshot for this gene.
All Summaries
Key Links
Genomic Location
Cytogenetic map
8A1-8A2
Sequence location
X:8,681,252..8,688,760 [+]
Recombination map
1-24
RefSeq locus
NC_004354 REGION:8681252..8688760
Sequence
Get Decorated FASTA
Genomic Maps
Other Genome Views
The following external sites may use different assemblies or annotations than FlyBase.
NCBI
UCSC
Ensembl
PopFly
Function
GO Summary Ribbons
Gene Ontology (GO) Annotations (5 terms)
Molecular Function (3 terms)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (3 terms)
CV Term
Evidence
References
enables carbonate dehydratase activity
inferred from biological aspect of ancestor with PANTHER:PTN001055642
(assigned by GO_Central )
(Gaudet et al., 2011)
enables hydro-lyase activity
inferred from biological aspect of ancestor with PANTHER:PTN001825752
(assigned by GO_Central )
(Gaudet et al., 2011)
enables zinc ion binding
inferred from electronic annotation with InterPro:IPR023561
(assigned by InterPro )
(FlyBase Curators et al., 2004-)
Biological Process (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
involved_in one-carbon metabolic process
inferred from biological aspect of ancestor with PANTHER:PTN001825752
(assigned by GO_Central )
(Gaudet et al., 2011)
Cellular Component (1 term)
Terms Based on Experimental Evidence (0 terms)
Terms Based on Predictions or Assertions (1 term)
CV Term
Evidence
References
is_active_in plasma membrane
inferred from biological aspect of ancestor with PANTHER:PTN001055642
(assigned by GO_Central )
(Gaudet et al., 2011)
Gene Group (FlyBase)
Protein Family (UniProt)
-
Protein Signatures (InterPro)
Catalytic Activity (EC)
Experimental Evidence
-
Predictions / Assertions
H(2)CO(3) = CO(2) + H(2)O (4.2.1.1)
Summaries
Gene Group (FlyBase)
CARBONIC ANHYDRASES -
Carbonic anhydrases (CA) are metalloenzymes that catalyze the reversible hydration/dehydration of carbon dioxide to bicarbonate and protons. (Adapted from FBrf0220988 and FBrf0229332).
Gene Model and Products
Number of Transcripts
5
Number of Unique Polypeptides
1

Please see the JBrowse view of Dmel\CAH3 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Protein Domains (via Pfam)
Isoform displayed:
Pfam protein domains
InterPro name
classification
start
end
Protein Domains (via SMART)
Isoform displayed:
SMART protein domains
InterPro name
classification
start
end
Comments on Gene Model

Low-frequency RNA-Seq exon junction(s) not annotated.

Gene model reviewed during 5.45

Gene model reviewed during 5.56

Sequence Ontology: Class of Gene
nuclear_gene
protein_coding_gene
Transcript Data
Annotated Transcripts
Name
FlyBase ID
RefSeq ID
Length (nt)
Assoc. CDS (aa)
CAH3-RA
FBtr0071222
NM_132269
2010
250
CAH3-RB
FBtr0331729
NM_001272420
1801
250
CAH3-RC
FBtr0331730
NM_001272421
1897
250
CAH3-RD
FBtr0331731
NM_001272422
1650
250
CAH3-RE
FBtr0345984
NM_001298094
2309
250
Additional Transcript Data and Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name
FlyBase ID
Predicted MW (kDa)
Length (aa)
Theoretical pI
RefSeq ID
GenBank
CAH3-PA
FBpp0071167
28.8
250
6.90
NP_572497
AAF46402
CAH3-PB
FBpp0304118
28.8
250
6.90
NP_001259349
AGB95192
CAH3-PC
FBpp0304119
28.8
250
6.90
NP_001259350
AGB95193
CAH3-PD
FBpp0304120
28.8
250
6.90
NP_001259351
AGB95194
CAH3-PE
FBpp0311871
28.8
250
6.90
NP_001285023
AHN59494
Polypeptides with Identical Sequences

The group(s) of polypeptides indicated below share identical sequence to each other.

250 aa isoforms: CAH3-PA, CAH3-PB, CAH3-PC, CAH3-PD, CAH3-PE
Additional Polypeptide Data and Comments
Reported size (kDa)
Comments
External Data
Crossreferences
InterPro - A database of protein families, domains and functional sites
Linkouts
Sequences Consistent with the Gene Model
Mapped Features

Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\CAH3 using the Feature Mapper tool.

External Data
Crossreferences
Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
Linkouts
Expression Data
Expression Summary Ribbons
Colored tiles in ribbon indicate that expression data has been curated by FlyBase for that anatomical location. Colorless tiles indicate that there is no curated data for that location.
For complete stage-specific expression data, view the modENCODE Development RNA-Seq section under High-Throughput Expression below.
Transcript Expression
microinjection
Stage
Tissue/Position (including subcellular localization)
Reference
larval stage
embryonic/larval midgut

Comment: enriched in transitional region

(Overend et al., 2016)
gastric caecum
(Overend et al., 2016)
Additional Descriptive Data

RNA-seq data show that CAH3 is expressed in the gastric caecum and throughout the larval midgut but is enriched in the transitional region of the midgut.

(Overend et al., 2016)
Marker for
 
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy
Stage
Tissue/Position (including subcellular localization)
Reference
adult stage
adult head
(Aradska et al., 2015)
Additional Descriptive Data
Marker for
 
Subcellular Localization
CV Term
Evidence
References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools

GBrowse - Visual display of RNA-Seq signals

View Dmel\CAH3 in GBrowse 2
RNA-Seq by Region - Search RNA-Seq expression levels by exon or genomic region
Bulk Downloads
RNA-Seq RPKM values for all genes
Reference
See Gelbart and Emmert, 2013 for analysis details and data files for all genes.
Developmental Proteome: Life Cycle
Developmental Proteome: Embryogenesis
External Data and Images
Linkouts
DRscDB
EMBL-EBI Single Cell Expression Atlas
FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
Flygut - An atlas of the Drosophila adult midgut
Images
FlyBase Wiki
Image Based Resources
Alleles, Insertions, Transgenic Constructs, and Aberrations
Classical and Insertion Alleles ( 7 )
For All Classical and Insertion Alleles Show
 
Other relevant insertions
Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Transgenic constructs containing/affecting coding region of CAH3
Transgenic constructs containing regulatory region of CAH3
Aberrations (Deficiencies and Duplications) ( 1 )
Alleles Representing Disease-Implicated Variants
Phenotypes
For more details about a specific phenotype click on the relevant allele symbol.
Lethality
Allele
viable, with Scer\GAL4Mef2.PR
viable, with Scer\GAL4pnr-MD237
Phenotype manifest in
Allele
Orthologs
Downloads
Download All DIOPT Orthologs
Download All OrthoDB Orthologs
Human Orthologs (via DIOPT v8.0)
Homo sapiens (Human) (19)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Hsap\CA1
3 of 15
Yes
No
Hsap\CA3
3 of 15
Yes
No
1  
Hsap\CA4
3 of 15
Yes
No
Hsap\CA5A
3 of 15
Yes
No
Hsap\CA5B
3 of 15
Yes
No
1  
Hsap\CA6
3 of 15
Yes
No
Hsap\CA7
3 of 15
Yes
No
Hsap\CA9
3 of 15
Yes
No
Hsap\CA12
3 of 15
Yes
No
Hsap\CA13
3 of 15
Yes
No
Hsap\CA14
3 of 15
Yes
No
Hsap\CA2
2 of 15
No
No
Hsap\CA10
2 of 15
No
No
1  
Hsap\CA11
2 of 15
No
No
Hsap\CA8
1 of 15
No
No
Hsap\OGN
1 of 15
No
Yes
Hsap\PNP
1 of 15
No
No
Hsap\PTPRG
1 of 15
No
No
Hsap\SERPINC1
1 of 15
No
No
1  
Model Organism Orthologs (via DIOPT v8.0)
Mus musculus (laboratory mouse) (17)
Species\Gene Symbol
Score
Best Score
Best Reverse Score
Source
Compara
eggNOG
Hieranoid
Homologene
Inparanoid
Isobase
OMA
OrthoDB
OrthoFinder
OrthoInspector
orthoMCL
Panther
Phylome
RoundUp
TreeFam
ZFIN
Alignment
Complementation?
Transgene?
Mmus\Car7
4 of 15
Yes
No
Mmus\Car1
3 of 15
No
No
Mmus\Car2
3 of 15
No
No
Mmus\Car3
3 of 15
No
No
Mmus\Car4
3 of 15
No
No
Mmus\Car5a
3 of 15
No
No
Mmus\Car5b
3 of 15
No
No
Mmus\Car6
3 of 15
No
No
Mmus\Car9
3 of 15
No
No
Mmus\Car12
3 of 15
No
No
Mmus\Car14
3 of 15
No
No
Mmus\Car15
3 of 15
No
No
Mmus\Car8
2 of 15
No
No
Mmus\Car10
2 of 15
No
No
Mmus\Car11
2 of 15
No
No
Mmus\Car13
2 of 15
No
No
Mmus\Ptprg
1 of 15
No
No
Rattus norvegicus (Norway rat) (18)
Rnor\Ca3
3 of 13
Yes
No
Rnor\Ca4
3 of 13
Yes
No
Rnor\Ca5a
3 of 13
Yes
No
Rnor\Ca5b
3 of 13
Yes
No
Rnor\Ca6
3 of 13
Yes
No
Rnor\Ca9
3 of 13
Yes
No
Rnor\Ca12
3 of 13
Yes
No
Rnor\Ca13
3 of 13
Yes
No
Rnor\Ca14
3 of 13
Yes
No
Rnor\Car1
3 of 13
Yes
No
Rnor\Car2
3 of 13
Yes
No
Rnor\Car7
3 of 13
Yes
No
Rnor\Ca8
2 of 13
No
No
Rnor\Ca11
2 of 13
No
No
Rnor\Car10
2 of 13
No
No
Rnor\Car15
2 of 13
No
No
Rnor\LOC103693605
2 of 13
No
No
Rnor\Ptprg
1 of 13
No
No
Xenopus tropicalis (Western clawed frog) (18)
Xtro\ca1
3 of 12
Yes
No
Xtro\ca2
3 of 12
Yes
No
Xtro\ca3
3 of 12
Yes
No
Xtro\ca5b
3 of 12
Yes
No
Xtro\ca7
3 of 12
Yes
No
Xtro\car1_predicted
3 of 12
Yes
No
Xtro\ca4
2 of 12
No
No
Xtro\ca6
2 of 12
No
No
Xtro\ca8
2 of 12
No
No
Xtro\ca10
2 of 12
No
No
Xtro\ca11
2 of 12
No
No
Xtro\ca12
2 of 12
No
No
Xtro\ca14
2 of 12
No
No
Xtro\LOC779564
2 of 12
No
No
Xtro\ca9
1 of 12
No
Yes
Xtro\ca13
1 of 12
No
No
Xtro\LOC100496280
1 of 12
No
Yes
Xtro\LOC108644694
1 of 12
No
Yes
Danio rerio (Zebrafish) (22)
Drer\ca2
3 of 15
Yes
No
Drer\ca4a
3 of 15
Yes
No
Drer\ca4b
3 of 15
Yes
No
Drer\ca4c
3 of 15
Yes
No
Drer\ca5a
3 of 15
Yes
No
Drer\ca6
3 of 15
Yes
No
Drer\ca7
3 of 15
Yes
No
Drer\ca9
3 of 15
Yes
No
Drer\ca12
3 of 15
Yes
No
Drer\ca14
3 of 15
Yes
No
Drer\ca15a
3 of 15
Yes
No
Drer\ca15b
3 of 15
Yes
No
Drer\ca15c
3 of 15
Yes
No
Drer\cahz
3 of 15
Yes
No
Drer\car15
3 of 15
Yes
No
Drer\zgc:153760
3 of 15
Yes
No
Drer\ca8
2 of 15
No
No
Drer\ca10a
2 of 15
No
No
Drer\ca10b
2 of 15
No
No
Drer\si:ch211-173d10.4
2 of 15
No
No
Drer\ca16b
1 of 15
No
No
Drer\ptprga
1 of 15
No
No
Caenorhabditis elegans (Nematode, roundworm) (6)
Cele\cah-3
4 of 15
Yes
No
Cele\cah-5
4 of 15
Yes
No
Cele\cah-4
3 of 15
No
No
Cele\cah-6
3 of 15
No
No
Cele\cah-1
2 of 15
No
No
Cele\cah-2
2 of 15
No
No
Arabidopsis thaliana (thale-cress) (8)
Atha\ACA1
6 of 9
Yes
No
Atha\ACA3
6 of 9
Yes
No
Atha\ACA6
6 of 9
Yes
No
Atha\ACA5
5 of 9
No
No
Atha\ACA7
5 of 9
No
No
Atha\ACA8
5 of 9
No
No
Atha\ACA2
4 of 9
No
No
Atha\ACA4
4 of 9
No
No
Saccharomyces cerevisiae (Brewer's yeast) (0)
No records found.
Schizosaccharomyces pombe (Fission yeast) (0)
No records found.
Ortholog(s) in Drosophila Species (via OrthoDB v9.1) ( EOG09190DIH )
Organism
Common Name
Gene
AAA Syntenic Ortholog
Multiple Dmel Genes in this Orthologous Group
Drosophila simulans
Dsim\GD16911
Drosophila sechellia
Dsec\GM21755
Drosophila erecta
Dere\GG18267
Drosophila yakuba
Dyak\GE15797
Drosophila ananassae
Dana\GF19158
Drosophila pseudoobscura pseudoobscura
Dpse\GA10890
Drosophila persimilis
Dper\GL12953
Drosophila willistoni
Dwil\GK10304
Drosophila virilis
Dvir\GJ19272
Drosophila mojavensis
Dmoj\GI15514
Drosophila grimshawi
Dgri\GH24456
Orthologs in non-Drosophila Dipterans (via OrthoDB v9.1) ( EOG09150AO0 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Musca domestica
House fly
Mdoa\17012097
Lucilia cuprina
Australian sheep blowfly
Lcup\FF38_12362
Mayetiola destructor
Hessian fly
Mdes\Mdes011646
Aedes aegypti
Yellow fever mosquito
Aaeg\AAEL005520
Anopheles darlingi
American malaria mosquito
Adar\ADAC009373
Anopheles gambiae
Malaria mosquito
Agam\CA
Anopheles gambiae
Malaria mosquito
Agam\AGAP000401
Anopheles gambiae
Malaria mosquito
Agam\AGAP012656
Culex quinquefasciatus
Southern house mosquito
Cqui\CPIJ011533
Orthologs in non-Dipteran Insects (via OrthoDB v9.1) ( EOG090W05J8 )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Bombyx mori
Silkmoth
Bmor\BGIBMGA008042
Danaus plexippus
Monarch butterfly
Dple\DPOGS209805-PA
Heliconius melpomene
Postman butterfly
Hmel\HMEL011869
Dendroctonus ponderosae
Mountain pine beetle
Dpod\YQE_04565
Tribolium castaneum
Red flour beetle
Tcas\TC000608
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI23752
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI072951
Acyrthosiphon pisum
Pea aphid
Apim\ACYPI009269
Orthologs in non-Insect Arthropods (via OrthoDB v9.1) ( None identified )
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (via OrthoDB v9.1) ( EOG091G0XFM )
Organism
Common Name
Gene
Multiple Dmel Genes in this Orthologous Group
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Cara14LA
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Cara12LA
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Cara8LB
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Cara8LA
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Cara2LA
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Cara2LB
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Cara1LA
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Cara4LB
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Cara5L
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Cara12LD
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Cara4LA
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Cara7LB
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Cah14L
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Cara12LB
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Cara7LA
Strongylocentrotus purpuratus
Purple sea urchin
Spur\Sp-Cara1LB
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000012565
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000014586
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000010731
Ciona intestinalis
Vase tunicate
Cint\ENSCING00000014543
Gallus gallus
Domestic chicken
Ggal\CA2
Gallus gallus
Domestic chicken
Ggal\CA8
Gallus gallus
Domestic chicken
Ggal\CA6
Gallus gallus
Domestic chicken
Ggal\CA5B
Gallus gallus
Domestic chicken
Ggal\CA9
Gallus gallus
Domestic chicken
Ggal\CA7
Gallus gallus
Domestic chicken
Ggal\LOC416927
Gallus gallus
Domestic chicken
Ggal\CA13
Gallus gallus
Domestic chicken
Ggal\CA3
Gallus gallus
Domestic chicken
Ggal\CA4
Gallus gallus
Domestic chicken
Ggal\ENSGALG00000028764
Gallus gallus
Domestic chicken
Ggal\ENSGALG00000027638
Gallus gallus
Domestic chicken
Ggal\CA12
Paralogs
Downloads
Download All DIOPT Paralogs
Paralogs (via DIOPT v8.0)
Drosophila melanogaster (Fruit fly) (14)
Gene Symbol
Score
Source
Compara
eggNOG
Homologene
Inparanoid
Isobase
OrthoDB
OrthoFinder
orthoMCL
Panther
RoundUp
Alignment
CAH1
4 of 10
CAH2
4 of 10
CAH4
4 of 10
CAH5
4 of 10
CAH6
4 of 10
CAH7
4 of 10
CAH8
4 of 10
CAH9
4 of 10
CAH15
4 of 10
CARPA
4 of 10
CARPB
4 of 10
CAH13
3 of 10
CAH14
3 of 10
CAH16
3 of 10
Human Disease Associations
FlyBase Human Disease Model Reports
    Disease Model Summary Ribbon
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Evidence
    References
    Potential Models Based on Orthology ( 1 )
    Human Ortholog
    Disease
    Evidence
    References
    CA12; carbonic anhydrase 12
    model of  isolated hyperchlorhidrosis
    IEA
    (FlyBase, 2019-)
    Modifiers Based on Experimental Evidence ( 0 )
    Allele
    Disease
    Interaction
    References
    Disease Associations of Human Orthologs (via DIOPT v8.0 and OMIM)
    Note that ortholog calls supported by only 1 or 2 algorithms (DIOPT score < 3) are not shown.
    Homo sapiens (Human)
    Gene name
    Score
    OMIM
    OMIM Phenotype
    DO term
    Complementation?
    Transgene?
    CA1; carbonic anhydrase 1
    3 of 15
    114800
        CA3; carbonic anhydrase 3
        3 of 15
        114750
             
            CA4; carbonic anhydrase 4
            3 of 15
            114760
                CA5A; carbonic anhydrase 5A
                3 of 15
                114761
                  CA5B; carbonic anhydrase 5B
                  3 of 15
                  300230
                       
                      CA6; carbonic anhydrase 6
                      3 of 15
                      114780
                          CA7; carbonic anhydrase 7
                          3 of 15
                          114770
                              CA9; carbonic anhydrase 9
                              3 of 15
                              603179
                                  CA12; carbonic anhydrase 12
                                  3 of 15
                                  603263
                                  CA13; carbonic anhydrase 13
                                  3 of 15
                                  611436
                                      CA14; carbonic anhydrase 14
                                      3 of 15
                                      604832
                                          Functional Complementation Data
                                          Functional complementation data is computed by FlyBase using a combination of the orthology data obtained from DIOPT and OrthoDB and the allele-level genetic interaction data curated from the literature.
                                          Interactions
                                          Summary of Physical Interactions
                                          esyN Network Diagram
                                          Interactions Browser
                                          Summary of Genetic Interactions
                                          esyN Network Diagram
                                          Starting gene(s)
                                          Interaction type
                                          Interacting gene(s)
                                          Reference
                                          Starting gene(s)
                                          Interaction type
                                          Interacting gene(s)
                                          Reference
                                          External Data
                                          Linkouts
                                          BioGRID - A database of protein and genetic interactions.
                                          DroID - A comprehensive database of gene and protein interactions.
                                          InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
                                          Pathways
                                          Signaling Pathways (FlyBase)
                                          Metabolic Pathways
                                          FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel
                                          KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
                                          External Data
                                          Linkouts
                                          Genomic Location and Detailed Mapping Data
                                          Chromosome (arm)
                                          X
                                          Recombination map
                                          1-24
                                          Cytogenetic map
                                          8A1-8A2
                                          Sequence location
                                          X:8,681,252..8,688,760 [+]
                                          FlyBase Computed Cytological Location
                                          Cytogenetic map
                                          Evidence for location
                                          8A1-8A2
                                          Limits computationally determined from genome sequence between P{EP}CG1632EP1583 and P{EP}MoeEP1652
                                          Experimentally Determined Cytological Location
                                          Cytogenetic map
                                          Notes
                                          References
                                          Experimentally Determined Recombination Data
                                          Location

                                          1-24

                                          (FlyBase, 2016)

                                          1-24.4

                                          (Comeron et al., 2012)
                                          Left of (cM)
                                          Right of (cM)
                                          Notes
                                          Stocks and Reagents
                                          Stocks (5)
                                          Genomic Clones (18)
                                           

                                          Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

                                          cDNA Clones (46)
                                           

                                          Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

                                          cDNA clones, fully sequenced
                                          BDGP DGC clones
                                          Other clones
                                            Drosophila Genomics Resource Center cDNA clones

                                            For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.

                                            cDNA Clones, End Sequenced (ESTs)
                                            BDGP DGC clones
                                            Other clones
                                            RNAi and Array Information
                                            Linkouts
                                            DRSC - Results frm RNAi screens
                                            GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                                            Antibody Information
                                            Laboratory Generated Antibodies
                                             
                                            Commercially Available Antibodies
                                             
                                            Other Information
                                            Relationship to Other Genes
                                            Source for database identify of

                                            Source for identity of: CAH3 CG11284

                                            (Ortutay et al., 2010)
                                            Source for database merge of
                                            Additional comments
                                            Other Comments
                                            Origin and Etymology
                                            Discoverer
                                            Etymology
                                            Identification
                                            External Crossreferences and Linkouts ( 50 )
                                            Sequence Crossreferences
                                            NCBI Gene - Gene integrates information from a wide range of species. A record may include nomenclature, Reference Sequences (RefSeqs), maps, pathways, variations, phenotypes, and links to genome-, phenotype-, and locus-specific resources worldwide.
                                            GenBank Nucleotide - A collection of sequences from several sources, including GenBank, RefSeq, TPA, and PDB.
                                            GenBank Protein - A collection of sequences from several sources, including translations from annotated coding regions in GenBank, RefSeq and TPA, as well as records from SwissProt, PIR, PRF, and PDB.
                                            RefSeq - A comprehensive, integrated, non-redundant, well-annotated set of reference sequences including genomic, transcript, and protein.
                                            UniProt/TrEMBL - Automatically annotated and unreviewed records of protein sequence and functional information
                                            Other crossreferences
                                            Drosophila Genomics Resource Center - Drosophila Genomics Resource Center (DGRC) cDNA clones
                                            DRscDB
                                            EMBL-EBI Single Cell Expression Atlas
                                            Eukaryotic Promoter Database - A collection of databases of experimentally validated promoters for selected model organisms.
                                            Fly-FISH - A database of Drosophila embryo and larvae mRNA localization patterns
                                            Flygut - An atlas of the Drosophila adult midgut
                                            GenomeRNAi - A database for cell-based and in vivo RNAi phenotypes and reagents
                                            iBeetle-Base - RNAi phenotypes in the red flour beetle (Tribolium castaneum)
                                            InterPro - A database of protein families, domains and functional sites
                                            KEGG Genes - Molecular building blocks of life in the genomic space.
                                            MARRVEL_MODEL
                                            modMine - A data warehouse for the modENCODE project
                                            Linkouts
                                            BioGRID - A database of protein and genetic interactions.
                                            DroID - A comprehensive database of gene and protein interactions.
                                            DRSC - Results frm RNAi screens
                                            FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array
                                            FlyCyc Genes - Genes from a BioCyc PGDB for Dmel
                                            FlyCyc Pathways - Pathways from a BioCyc PGDB for Dmel
                                            FlyMine - An integrated database for Drosophila genomics
                                            InterologFinder - Protein-protein interactions (PPI) from both known and predicted PPI data sets.
                                            KEGG Pathways - Wiring diagrams of molecular interactions, reactions and relations.
                                            Synonyms and Secondary IDs (4)
                                            Reported As
                                            Symbol Synonym
                                            CAH3
                                            (Ortutay et al., 2010)
                                            CG11284
                                            (Overend et al., 2016, Ortutay et al., 2010, Keleman et al., 2009.8.5, Linser et al., 2009, Perkins et al., 2009, Blumenthal, 2008, Macdonald and Long, 2007)
                                            CG11285
                                            (Aby et al., 2013)
                                            Name Synonyms
                                            Carbonic anhydrase 3
                                            Secondary FlyBase IDs
                                              Datasets (0)
                                              Study focus (0)
                                              Experimental Role
                                              Project
                                              Project Type
                                              Title
                                              References (32)