Gene Dmel\CG7033

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General Information

Symbol

Dmel\CG7033

Species

D. melanogaster

Name

Annotation symbol

CG7033

Feature type

protein_coding_gene

FlyBase ID

FBgn0030086

Gene Model Status

Current

Stock availability

4 publicly available

Also Known As

CCT2

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

8C8-8C8

Sequence location

X:8,983,546..8,986,859 [+]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG7033 (FBgn0030086). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: unfolded protein binding; ATP binding. There is experimental evidence that it is involved in the biological process: mitotic spindle organization; centrosome duplication; cytoplasmic microtubule organization; neurogenesis. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Chaperone, tailless complex polypeptide 1; Chaperonin Cpn60/TCP-1; Chaperonin TCP-1, conserved site; T-complex protein 1, beta subunit. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval Malpighian tubules, adult fat body, larval salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult brain, adult Malpighian tubules, adult heart, larval fat body, adult salivary gland, virgin spermatheca, adult testis, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1630408_s_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG7033. Gene sequence location is X:8983546..8986859.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

8C8-8C8

Limits computationally determined from genome sequence between P{EP}CG10962^EP1565&P{EP}EP1030 and P{EP}EP1450&P{EP}EP1356

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG7033 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.40

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG7033-RA

FBtr0071289

NM_132296

2121

535

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG7033-PA

FBpp0071226

58.1

535

5.59

NP_572524

AAF46442

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Chaperonin TCP-1, conserved site (IPR002194)

Chaperonin Cpn60/TCP-1 (IPR002423)

T-complex protein 1, beta subunit (IPR012716)

Chaperone tailless complex polypeptide 1 (TCP-1) (IPR017998)

TCP-1-like chaperonin intermediate domain (IPR027410)

GroEL-like apical domain (IPR027409)

GroEL-like equatorial domain (IPR027413)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

in situ

Stage

Tissue/Position (including subcellular localization)

Reference

embryonic stage 1 -- 3

organism

(Fisher et al., 2012)

Comment:maternally deposited

embryonic stage 4 -- 6

organism

(Fisher et al., 2012)

embryonic stage 7 -- 8

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 9 -- 10

organism | ubiquitous

(Fisher et al., 2012)

embryonic stage 11 -- 12

anterior midgut primordium

(Fisher et al., 2012)

organism | ubiquitous

(Fisher et al., 2012)

posterior midgut primordium

(Fisher et al., 2012)

trunk mesoderm

(Fisher et al., 2012)

embryonic stage 13 -- 16

embryonic anal pad

(Fisher et al., 2012)

embryonic hindgut

(Fisher et al., 2012)

embryonic/larval dorsal vessel

(Fisher et al., 2012)

embryonic/larval lymph gland

(Fisher et al., 2012)

embryonic/larval midgut

(Fisher et al., 2012)

embryonic/larval muscle system

(Fisher et al., 2012)

organism | ubiquitous

(Fisher et al., 2012)

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

mass spectroscopy

Stage

Tissue/Position (including subcellular localization)

Reference

day 7 of adulthood -- day 49 of adulthood

adult heart

(Cammarato et al., 2011)

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

lipid particle

inferred from direct assay

(Cermelli et al., 2006)

microtubule associated complex

inferred from direct assay

(Hughes et al., 2008)

mitotic spindle

inferred from direct assay

(Müller et al., 2010)

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval Malpighian tubules, adult fat body, larval salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult brain, adult Malpighian tubules, adult heart, larval fat body, adult salivary gland, virgin spermatheca, adult testis, adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		1581.575
Larval Midgut		933.9
Larval Hindgut		1571.4
Larval Malpighian Tubules		718.3
Larval Fat Body		486.1
Larval Salivary Gland		1239.3
Larval Trachea		1132.025
Larval Carcass		1710.475
Adult Head		428.2
Adult Eye		220.25
Adult Brain		441.3
Adult Thoracic-Abdominal Ganglion		634.7
Adult Crop		919.7
Adult Midgut		877.2
Adult Hindgut		700.3
Adult Malpighian Tubules		484
Adult Fat Body		716.1
Adult Salivary Gland		376.6
Adult Heart		485.025
Adult VirginFemale Spermatheca		394.5
Adult InseminatedFemale Spermatheca		624.6
Adult Ovary		2099.8
Adult Testis		428.9
Adult Male Accessory Gland		1202.7
Adult Carcass		441.6
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		(1581.575)
Larval Midgut		(933.9)
Larval Hindgut		(1571.4)
Larval Malpighian Tubules		(718.3)
Larval Fat Body		486.1
Larval Salivary Gland		(1239.3)
Larval Trachea		(1132.025)
Larval Carcass		(1710.475)
Adult Head		428.2
Adult Eye		220.25
Adult Brain		441.3
Adult Thoracic-Abdominal Ganglion		(634.7)
Adult Crop		(919.7)
Adult Midgut		(877.2)
Adult Hindgut		(700.3)
Adult Malpighian Tubules		484
Adult Fat Body		(716.1)
Adult Salivary Gland		376.6
Adult Heart		485.025
Adult VirginFemale Spermatheca		394.5
Adult InseminatedFemale Spermatheca		(624.6)
Adult Ovary		(2099.8)
Adult Testis		428.9
Adult Male Accessory Gland		(1202.7)
Adult Carcass		441.6
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		(1581.575)
Larval Midgut		933.9
Larval Hindgut		(1571.4)
Larval Malpighian Tubules		718.3
Larval Fat Body		486.1
Larval Salivary Gland		(1239.3)
Larval Trachea		(1132.025)
Larval Carcass		(1710.475)
Adult Head		428.2
Adult Eye		220.25
Adult Brain		441.3
Adult Thoracic-Abdominal Ganglion		634.7
Adult Crop		919.7
Adult Midgut		877.2
Adult Hindgut		700.3
Adult Malpighian Tubules		484
Adult Fat Body		716.1
Adult Salivary Gland		376.6
Adult Heart		485.025
Adult VirginFemale Spermatheca		394.5
Adult InseminatedFemale Spermatheca		624.6
Adult Ovary		(2099.8)
Adult Testis		428.9
Adult Male Accessory Gland		(1202.7)
Adult Carcass		441.6
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		1581.575
Larval Midgut		933.9
Larval Hindgut		1571.4
Larval Malpighian Tubules		718.3
Larval Fat Body		486.1
Larval Salivary Gland		1239.3
Larval Trachea		1132.025
Larval Carcass		1710.475
Adult Head		428.2
Adult Eye		220.25
Adult Brain		441.3
Adult Thoracic-Abdominal Ganglion		634.7
Adult Crop		919.7
Adult Midgut		877.2
Adult Hindgut		700.3
Adult Malpighian Tubules		484
Adult Fat Body		716.1
Adult Salivary Gland		376.6
Adult Heart		485.025
Adult VirginFemale Spermatheca		394.5
Adult InseminatedFemale Spermatheca		624.6
Adult Ovary		2099.8
Adult Testis		428.9
Adult Male Accessory Gland		1202.7
Adult Carcass		441.6
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		1581.575
Larval Midgut		933.9
Larval Hindgut		1571.4
Larval Malpighian Tubules		718.3
Larval Fat Body		486.1
Larval Salivary Gland		1239.3
Larval Trachea		1132.025
Larval Carcass		1710.475
Adult Head		428.2
Adult Eye		220.25
Adult Brain		441.3
Adult Thoracic-Abdominal Ganglion		634.7
Adult Crop		919.7
Adult Midgut		877.2
Adult Hindgut		700.3
Adult Malpighian Tubules		484
Adult Fat Body		716.1
Adult Salivary Gland		376.6
Adult Heart		485.025
Adult VirginFemale Spermatheca		394.5
Adult InseminatedFemale Spermatheca		624.6
Adult Ovary		2099.8
Adult Testis		428.9
Adult Male Accessory Gland		1202.7
Adult Carcass		441.6
Expression Level Scale		None Low Moderate High Very high

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		(1581.575)
Larval Midgut		(933.9)
Larval Hindgut		(1571.4)
Larval Malpighian Tubules		718.3
Larval Fat Body		486.1
Larval Salivary Gland		(1239.3)
Larval Trachea		(1132.025)
Larval Carcass		(1710.475)
Adult Head		428.2
Adult Eye		220.25
Adult Brain		441.3
Adult Thoracic-Abdominal Ganglion		634.7
Adult Crop		(919.7)
Adult Midgut		(877.2)
Adult Hindgut		700.3
Adult Malpighian Tubules		484
Adult Fat Body		716.1
Adult Salivary Gland		376.6
Adult Heart		485.025
Adult VirginFemale Spermatheca		394.5
Adult InseminatedFemale Spermatheca		624.6
Adult Ovary		(2099.8)
Adult Testis		428.9
Adult Male Accessory Gland		(1202.7)
Adult Carcass		441.6
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		1581.575
Larval Midgut		933.9
Larval Hindgut		1571.4
Larval Malpighian Tubules		718.3
Larval Fat Body		486.1
Larval Salivary Gland		1239.3
Larval Trachea		1132.025
Larval Carcass		1710.475
Adult Head		428.2
Adult Eye		220.25
Adult Brain		441.3
Adult Thoracic-Abdominal Ganglion		634.7
Adult Crop		919.7
Adult Midgut		877.2
Adult Hindgut		700.3
Adult Malpighian Tubules		484
Adult Fat Body		716.1
Adult Salivary Gland		376.6
Adult Heart		485.025
Adult VirginFemale Spermatheca		394.5
Adult InseminatedFemale Spermatheca		624.6
Adult Ovary		(2099.8)
Adult Testis		428.9
Adult Male Accessory Gland		1202.7
Adult Carcass		441.6
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		1581.575
Larval Midgut		933.9
Larval Hindgut		1571.4
Larval Malpighian Tubules		718.3
Larval Fat Body		486.1
Larval Salivary Gland		1239.3
Larval Trachea		1132.025
Larval Carcass		1710.475
Adult Head		428.2
Adult Eye		220.25
Adult Brain		441.3
Adult Thoracic-Abdominal Ganglion		634.7
Adult Crop		919.7
Adult Midgut		877.2
Adult Hindgut		700.3
Adult Malpighian Tubules		484
Adult Fat Body		716.1
Adult Salivary Gland		376.6
Adult Heart		485.025
Adult VirginFemale Spermatheca		394.5
Adult InseminatedFemale Spermatheca		624.6
Adult Ovary		2099.8
Adult Testis		428.9
Adult Male Accessory Gland		1202.7
Adult Carcass		441.6
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	428.2
NA	Eye	220.25
NA	Brain	441.3
1581.575	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	634.7
NA	Crop	919.7
933.9	Midgut	877.2
1571.4	Hindgut	700.3
718.3	Malpighian Tubules	484
486.1	Fat Body	716.1
1239.3	Salivary Gland	376.6
NA	Heart	485.025
1132.025	Trachea	NA
NA	VirginFemale Spermatheca	394.5
NA	InseminatedFemale Spermatheca	624.6
NA	Ovary	2099.8
NA	Testis	428.9
NA	Male Accessory Gland	1202.7
1710.475	Carcass	441.6

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		129
central nervous system, larvae L3		118
central nervous system, pupae P8		42
head, virgin 1-day female		15
head, virgin 4-day female		14
head, virgin 20-day female		21
head, mated 1-day female		13
head, mated 4-day female		31
head, mated 20-day female		18
head, mated 1-day male		15
head, mated 4-day male		24
head, mated 20-day male		29
salivary gland, larvae L3 wandering		4
salivary gland, white prepupae		13
digestive system, larvae L3 wandering		48
digestive system, 1-day adult		48
digestive system, 4-day adult		55
digestive system, 20-day adult		66
fat body, larvae L3 wandering		10
fat body, white prepupae		32
fat body, pupae P8		27
carcass, larvae L3 wandering		91
carcass, 1-day adult		25
carcass, 4-day adult		41
carcass, 20-day adult		35
ovary, virgin 4-day female		361
ovary, mated 4-day female		297
testis, mated 4-day male		72
accessory gland, mated 4-day male		40
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(129)
central nervous system, larvae L3		(118)
central nervous system, pupae P8		(42)
head, virgin 1-day female		15
head, virgin 4-day female		14
head, virgin 20-day female		21
head, mated 1-day female		13
head, mated 4-day female		(31)
head, mated 20-day female		18
head, mated 1-day male		15
head, mated 4-day male		24
head, mated 20-day male		(29)
salivary gland, larvae L3 wandering		4
salivary gland, white prepupae		13
digestive system, larvae L3 wandering		(48)
digestive system, 1-day adult		(48)
digestive system, 4-day adult		(55)
digestive system, 20-day adult		(66)
fat body, larvae L3 wandering		10
fat body, white prepupae		(32)
fat body, pupae P8		(27)
carcass, larvae L3 wandering		(91)
carcass, 1-day adult		25
carcass, 4-day adult		(41)
carcass, 20-day adult		(35)
ovary, virgin 4-day female		(361)
ovary, mated 4-day female		(297)
testis, mated 4-day male		(72)
accessory gland, mated 4-day male		(40)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(129)
central nervous system, larvae L3		(118)
central nervous system, pupae P8		42
head, virgin 1-day female		15
head, virgin 4-day female		14
head, virgin 20-day female		21
head, mated 1-day female		13
head, mated 4-day female		31
head, mated 20-day female		18
head, mated 1-day male		15
head, mated 4-day male		24
head, mated 20-day male		29
salivary gland, larvae L3 wandering		4
salivary gland, white prepupae		13
digestive system, larvae L3 wandering		48
digestive system, 1-day adult		48
digestive system, 4-day adult		55
digestive system, 20-day adult		66
fat body, larvae L3 wandering		10
fat body, white prepupae		32
fat body, pupae P8		27
carcass, larvae L3 wandering		91
carcass, 1-day adult		25
carcass, 4-day adult		41
carcass, 20-day adult		35
ovary, virgin 4-day female		(361)
ovary, mated 4-day female		(297)
testis, mated 4-day male		72
accessory gland, mated 4-day male		40
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		129
central nervous system, larvae L3		118
central nervous system, pupae P8		42
head, virgin 1-day female		15
head, virgin 4-day female		14
head, virgin 20-day female		21
head, mated 1-day female		13
head, mated 4-day female		31
head, mated 20-day female		18
head, mated 1-day male		15
head, mated 4-day male		24
head, mated 20-day male		29
salivary gland, larvae L3 wandering		4
salivary gland, white prepupae		13
digestive system, larvae L3 wandering		48
digestive system, 1-day adult		48
digestive system, 4-day adult		55
digestive system, 20-day adult		66
fat body, larvae L3 wandering		10
fat body, white prepupae		32
fat body, pupae P8		27
carcass, larvae L3 wandering		91
carcass, 1-day adult		25
carcass, 4-day adult		41
carcass, 20-day adult		35
ovary, virgin 4-day female		361
ovary, mated 4-day female		297
testis, mated 4-day male		72
accessory gland, mated 4-day male		40
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		129
central nervous system, larvae L3		118
central nervous system, pupae P8		42
head, virgin 1-day female		15
head, virgin 4-day female		14
head, virgin 20-day female		21
head, mated 1-day female		13
head, mated 4-day female		31
head, mated 20-day female		18
head, mated 1-day male		15
head, mated 4-day male		24
head, mated 20-day male		29
salivary gland, larvae L3 wandering		4
salivary gland, white prepupae		13
digestive system, larvae L3 wandering		48
digestive system, 1-day adult		48
digestive system, 4-day adult		55
digestive system, 20-day adult		66
fat body, larvae L3 wandering		10
fat body, white prepupae		32
fat body, pupae P8		27
carcass, larvae L3 wandering		91
carcass, 1-day adult		25
carcass, 4-day adult		41
carcass, 20-day adult		35
ovary, virgin 4-day female		361
ovary, mated 4-day female		297
testis, mated 4-day male		72
accessory gland, mated 4-day male		40
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		(129)
central nervous system, larvae L3		(118)
central nervous system, pupae P8		(42)
head, virgin 1-day female		15
head, virgin 4-day female		14
head, virgin 20-day female		21
head, mated 1-day female		13
head, mated 4-day female		31
head, mated 20-day female		18
head, mated 1-day male		15
head, mated 4-day male		24
head, mated 20-day male		29
salivary gland, larvae L3 wandering		4
salivary gland, white prepupae		13
digestive system, larvae L3 wandering		(48)
digestive system, 1-day adult		(48)
digestive system, 4-day adult		(55)
digestive system, 20-day adult		(66)
fat body, larvae L3 wandering		10
fat body, white prepupae		32
fat body, pupae P8		27
carcass, larvae L3 wandering		(91)
carcass, 1-day adult		25
carcass, 4-day adult		(41)
carcass, 20-day adult		(35)
ovary, virgin 4-day female		(361)
ovary, mated 4-day female		(297)
testis, mated 4-day male		(72)
accessory gland, mated 4-day male		(40)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		129
central nervous system, larvae L3		118
central nervous system, pupae P8		42
head, virgin 1-day female		15
head, virgin 4-day female		14
head, virgin 20-day female		21
head, mated 1-day female		13
head, mated 4-day female		31
head, mated 20-day female		18
head, mated 1-day male		15
head, mated 4-day male		24
head, mated 20-day male		29
salivary gland, larvae L3 wandering		4
salivary gland, white prepupae		13
digestive system, larvae L3 wandering		48
digestive system, 1-day adult		48
digestive system, 4-day adult		55
digestive system, 20-day adult		66
fat body, larvae L3 wandering		10
fat body, white prepupae		32
fat body, pupae P8		27
carcass, larvae L3 wandering		91
carcass, 1-day adult		25
carcass, 4-day adult		41
carcass, 20-day adult		35
ovary, virgin 4-day female		(361)
ovary, mated 4-day female		(297)
testis, mated 4-day male		72
accessory gland, mated 4-day male		40
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		129
central nervous system, larvae L3		118
central nervous system, pupae P8		42
head, virgin 1-day female		15
head, virgin 4-day female		14
head, virgin 20-day female		21
head, mated 1-day female		13
head, mated 4-day female		31
head, mated 20-day female		18
head, mated 1-day male		15
head, mated 4-day male		24
head, mated 20-day male		29
salivary gland, larvae L3 wandering		4
salivary gland, white prepupae		13
digestive system, larvae L3 wandering		48
digestive system, 1-day adult		48
digestive system, 4-day adult		55
digestive system, 20-day adult		66
fat body, larvae L3 wandering		10
fat body, white prepupae		32
fat body, pupae P8		27
carcass, larvae L3 wandering		91
carcass, 1-day adult		25
carcass, 4-day adult		41
carcass, 20-day adult		35
ovary, virgin 4-day female		361
ovary, mated 4-day female		297
testis, mated 4-day male		72
accessory gland, mated 4-day male		40
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-18 hour embryonic stages, during early larval stages, in adult female stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		489
embryo 02-04hr		63
embryo 04-06hr		63
embryo 06-08hr		126
embryo 08-10hr		145
embryo 10-12hr		274
embryo 12-14hr		135
embryo 14-16hr		149
embryo 16-18hr		103
embryo 18-20hr		75
embryo 20-22hr		72
embryo 22-24hr		54
larva L1		217
larva L2		180
larva L3 12hr old		145
larva L3 puffstage 1-2		69
larva L3 puffstage 3-6		103
larva L3 puffstage 7-9		117
white prepupae new		113
white prepupae 12hr		107
white prepupae 24hr		125
pupae 2d postWPP		77
pupae 3d postWPP		65
pupae 4d postWPP		64
adult male 01day		42
adult male 05day		51
adult male 30day		59
adult female 01day		281
adult female 05day		380
adult female 30day		396
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(489)
embryo 02-04hr		(63)
embryo 04-06hr		(63)
embryo 06-08hr		(126)
embryo 08-10hr		(145)
embryo 10-12hr		(274)
embryo 12-14hr		(135)
embryo 14-16hr		(149)
embryo 16-18hr		(103)
embryo 18-20hr		(75)
embryo 20-22hr		(72)
embryo 22-24hr		(54)
larva L1		(217)
larva L2		(180)
larva L3 12hr old		(145)
larva L3 puffstage 1-2		(69)
larva L3 puffstage 3-6		(103)
larva L3 puffstage 7-9		(117)
white prepupae new		(113)
white prepupae 12hr		(107)
white prepupae 24hr		(125)
pupae 2d postWPP		(77)
pupae 3d postWPP		(65)
pupae 4d postWPP		(64)
adult male 01day		(42)
adult male 05day		(51)
adult male 30day		(59)
adult female 01day		(281)
adult female 05day		(380)
adult female 30day		(396)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		(489)
embryo 02-04hr		63
embryo 04-06hr		63
embryo 06-08hr		(126)
embryo 08-10hr		(145)
embryo 10-12hr		(274)
embryo 12-14hr		(135)
embryo 14-16hr		(149)
embryo 16-18hr		103
embryo 18-20hr		75
embryo 20-22hr		72
embryo 22-24hr		54
larva L1		(217)
larva L2		(180)
larva L3 12hr old		(145)
larva L3 puffstage 1-2		69
larva L3 puffstage 3-6		103
larva L3 puffstage 7-9		(117)
white prepupae new		(113)
white prepupae 12hr		107
white prepupae 24hr		(125)
pupae 2d postWPP		77
pupae 3d postWPP		65
pupae 4d postWPP		64
adult male 01day		42
adult male 05day		51
adult male 30day		59
adult female 01day		(281)
adult female 05day		(380)
adult female 30day		(396)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		489
embryo 02-04hr		63
embryo 04-06hr		63
embryo 06-08hr		126
embryo 08-10hr		145
embryo 10-12hr		274
embryo 12-14hr		135
embryo 14-16hr		149
embryo 16-18hr		103
embryo 18-20hr		75
embryo 20-22hr		72
embryo 22-24hr		54
larva L1		217
larva L2		180
larva L3 12hr old		145
larva L3 puffstage 1-2		69
larva L3 puffstage 3-6		103
larva L3 puffstage 7-9		117
white prepupae new		113
white prepupae 12hr		107
white prepupae 24hr		125
pupae 2d postWPP		77
pupae 3d postWPP		65
pupae 4d postWPP		64
adult male 01day		42
adult male 05day		51
adult male 30day		59
adult female 01day		281
adult female 05day		380
adult female 30day		396
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		489
embryo 02-04hr		63
embryo 04-06hr		63
embryo 06-08hr		126
embryo 08-10hr		145
embryo 10-12hr		274
embryo 12-14hr		135
embryo 14-16hr		149
embryo 16-18hr		103
embryo 18-20hr		75
embryo 20-22hr		72
embryo 22-24hr		54
larva L1		217
larva L2		180
larva L3 12hr old		145
larva L3 puffstage 1-2		69
larva L3 puffstage 3-6		103
larva L3 puffstage 7-9		117
white prepupae new		113
white prepupae 12hr		107
white prepupae 24hr		125
pupae 2d postWPP		77
pupae 3d postWPP		65
pupae 4d postWPP		64
adult male 01day		42
adult male 05day		51
adult male 30day		59
adult female 01day		281
adult female 05day		380
adult female 30day		396
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		(489)
embryo 02-04hr		(63)
embryo 04-06hr		(63)
embryo 06-08hr		(126)
embryo 08-10hr		(145)
embryo 10-12hr		(274)
embryo 12-14hr		(135)
embryo 14-16hr		(149)
embryo 16-18hr		(103)
embryo 18-20hr		(75)
embryo 20-22hr		(72)
embryo 22-24hr		(54)
larva L1		(217)
larva L2		(180)
larva L3 12hr old		(145)
larva L3 puffstage 1-2		(69)
larva L3 puffstage 3-6		(103)
larva L3 puffstage 7-9		(117)
white prepupae new		(113)
white prepupae 12hr		(107)
white prepupae 24hr		(125)
pupae 2d postWPP		(77)
pupae 3d postWPP		(65)
pupae 4d postWPP		(64)
adult male 01day		(42)
adult male 05day		(51)
adult male 30day		(59)
adult female 01day		(281)
adult female 05day		(380)
adult female 30day		(396)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		(489)
embryo 02-04hr		63
embryo 04-06hr		63
embryo 06-08hr		126
embryo 08-10hr		(145)
embryo 10-12hr		(274)
embryo 12-14hr		135
embryo 14-16hr		(149)
embryo 16-18hr		103
embryo 18-20hr		75
embryo 20-22hr		72
embryo 22-24hr		54
larva L1		(217)
larva L2		(180)
larva L3 12hr old		(145)
larva L3 puffstage 1-2		69
larva L3 puffstage 3-6		103
larva L3 puffstage 7-9		117
white prepupae new		113
white prepupae 12hr		107
white prepupae 24hr		125
pupae 2d postWPP		77
pupae 3d postWPP		65
pupae 4d postWPP		64
adult male 01day		42
adult male 05day		51
adult male 30day		59
adult female 01day		(281)
adult female 05day		(380)
adult female 30day		(396)
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		489
embryo 02-04hr		63
embryo 04-06hr		63
embryo 06-08hr		126
embryo 08-10hr		145
embryo 10-12hr		274
embryo 12-14hr		135
embryo 14-16hr		149
embryo 16-18hr		103
embryo 18-20hr		75
embryo 20-22hr		72
embryo 22-24hr		54
larva L1		217
larva L2		180
larva L3 12hr old		145
larva L3 puffstage 1-2		69
larva L3 puffstage 3-6		103
larva L3 puffstage 7-9		117
white prepupae new		113
white prepupae 12hr		107
white prepupae 24hr		125
pupae 2d postWPP		77
pupae 3d postWPP		65
pupae 4d postWPP		64
adult male 01day		42
adult male 05day		51
adult male 30day		59
adult female 01day		281
adult female 05day		380
adult female 30day		396
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		369
Schneider line 2 Sg4		493
embryonic 1182-4H		229
embryonic GM2		475
embryonic Kc167		346
embryonic S1		617
embryonic S3		316
leg disc CME L1		335
wing disc CME-W2		281
wing disc ML-DmD8		183
wing disc ML-DmD9		313
wing disc ML-DmD16-c3		252
wing disc ML-DmD21		422
wing disc ML-DmD32		171
haltere disc ML-DmD17-c3		324
eye-antennal disc ML-DmD11		243
antennal disc ML-DmD20-c5		247
mixed discs ML-DmD4-c1		258
CNS ML-DmBG1-c1		239
CNS ML-DmBG2-c2		191
tumorous blood cells mbn2		165
ovary fGS/OSS		172
ovary OSC		161
ovary OSS		102
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(369)
Schneider line 2 Sg4		(493)
embryonic 1182-4H		(229)
embryonic GM2		(475)
embryonic Kc167		(346)
embryonic S1		(617)
embryonic S3		(316)
leg disc CME L1		(335)
wing disc CME-W2		(281)
wing disc ML-DmD8		(183)
wing disc ML-DmD9		(313)
wing disc ML-DmD16-c3		(252)
wing disc ML-DmD21		(422)
wing disc ML-DmD32		(171)
haltere disc ML-DmD17-c3		(324)
eye-antennal disc ML-DmD11		(243)
antennal disc ML-DmD20-c5		(247)
mixed discs ML-DmD4-c1		(258)
CNS ML-DmBG1-c1		(239)
CNS ML-DmBG2-c2		(191)
tumorous blood cells mbn2		(165)
ovary fGS/OSS		(172)
ovary OSC		(161)
ovary OSS		(102)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		(369)
Schneider line 2 Sg4		(493)
embryonic 1182-4H		(229)
embryonic GM2		(475)
embryonic Kc167		(346)
embryonic S1		(617)
embryonic S3		(316)
leg disc CME L1		(335)
wing disc CME-W2		(281)
wing disc ML-DmD8		(183)
wing disc ML-DmD9		(313)
wing disc ML-DmD16-c3		(252)
wing disc ML-DmD21		(422)
wing disc ML-DmD32		(171)
haltere disc ML-DmD17-c3		(324)
eye-antennal disc ML-DmD11		(243)
antennal disc ML-DmD20-c5		(247)
mixed discs ML-DmD4-c1		(258)
CNS ML-DmBG1-c1		(239)
CNS ML-DmBG2-c2		(191)
tumorous blood cells mbn2		(165)
ovary fGS/OSS		(172)
ovary OSC		(161)
ovary OSS		102
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		369
Schneider line 2 Sg4		493
embryonic 1182-4H		229
embryonic GM2		475
embryonic Kc167		346
embryonic S1		617
embryonic S3		316
leg disc CME L1		335
wing disc CME-W2		281
wing disc ML-DmD8		183
wing disc ML-DmD9		313
wing disc ML-DmD16-c3		252
wing disc ML-DmD21		422
wing disc ML-DmD32		171
haltere disc ML-DmD17-c3		324
eye-antennal disc ML-DmD11		243
antennal disc ML-DmD20-c5		247
mixed discs ML-DmD4-c1		258
CNS ML-DmBG1-c1		239
CNS ML-DmBG2-c2		191
tumorous blood cells mbn2		165
ovary fGS/OSS		172
ovary OSC		161
ovary OSS		102
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		369
Schneider line 2 Sg4		493
embryonic 1182-4H		229
embryonic GM2		475
embryonic Kc167		346
embryonic S1		617
embryonic S3		316
leg disc CME L1		335
wing disc CME-W2		281
wing disc ML-DmD8		183
wing disc ML-DmD9		313
wing disc ML-DmD16-c3		252
wing disc ML-DmD21		422
wing disc ML-DmD32		171
haltere disc ML-DmD17-c3		324
eye-antennal disc ML-DmD11		243
antennal disc ML-DmD20-c5		247
mixed discs ML-DmD4-c1		258
CNS ML-DmBG1-c1		239
CNS ML-DmBG2-c2		191
tumorous blood cells mbn2		165
ovary fGS/OSS		172
ovary OSC		161
ovary OSS		102
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		(369)
Schneider line 2 Sg4		(493)
embryonic 1182-4H		(229)
embryonic GM2		(475)
embryonic Kc167		(346)
embryonic S1		(617)
embryonic S3		(316)
leg disc CME L1		(335)
wing disc CME-W2		(281)
wing disc ML-DmD8		(183)
wing disc ML-DmD9		(313)
wing disc ML-DmD16-c3		(252)
wing disc ML-DmD21		(422)
wing disc ML-DmD32		(171)
haltere disc ML-DmD17-c3		(324)
eye-antennal disc ML-DmD11		(243)
antennal disc ML-DmD20-c5		(247)
mixed discs ML-DmD4-c1		(258)
CNS ML-DmBG1-c1		(239)
CNS ML-DmBG2-c2		(191)
tumorous blood cells mbn2		(165)
ovary fGS/OSS		(172)
ovary OSC		(161)
ovary OSS		(102)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		(369)
Schneider line 2 Sg4		(493)
embryonic 1182-4H		(229)
embryonic GM2		(475)
embryonic Kc167		(346)
embryonic S1		(617)
embryonic S3		(316)
leg disc CME L1		(335)
wing disc CME-W2		(281)
wing disc ML-DmD8		(183)
wing disc ML-DmD9		(313)
wing disc ML-DmD16-c3		(252)
wing disc ML-DmD21		(422)
wing disc ML-DmD32		(171)
haltere disc ML-DmD17-c3		(324)
eye-antennal disc ML-DmD11		(243)
antennal disc ML-DmD20-c5		(247)
mixed discs ML-DmD4-c1		(258)
CNS ML-DmBG1-c1		(239)
CNS ML-DmBG2-c2		(191)
tumorous blood cells mbn2		(165)
ovary fGS/OSS		(172)
ovary OSC		(161)
ovary OSS		102
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		369
Schneider line 2 Sg4		493
embryonic 1182-4H		229
embryonic GM2		475
embryonic Kc167		346
embryonic S1		617
embryonic S3		316
leg disc CME L1		335
wing disc CME-W2		281
wing disc ML-DmD8		183
wing disc ML-DmD9		313
wing disc ML-DmD16-c3		252
wing disc ML-DmD21		422
wing disc ML-DmD32		171
haltere disc ML-DmD17-c3		324
eye-antennal disc ML-DmD11		243
antennal disc ML-DmD20-c5		247
mixed discs ML-DmD4-c1		258
CNS ML-DmBG1-c1		239
CNS ML-DmBG2-c2		191
tumorous blood cells mbn2		165
ovary fGS/OSS		172
ovary OSC		161
ovary OSS		102
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		100
cold shock, 4-day adult		65
heat shock, 4-day adult		185
Cadmium 50 mM 6 hrs, larvae L3		96
Cadmium 50 mM 12 hrs, larvae L3		48
Cadmium 50 mM 48 hrs, 4-day adult		133
Cadmium 100 mM 48 hrs, 4-day adult		208
Copper 0.5 mM 12 hrs, larvae L3		58
Copper 15 mM 48 hrs, 4-day adult		153
Zinc 5 mM 12 hrs, larvae L3		46
Zinc 4.5 mM 48 hrs, 4-day adult		56
Ethanol 2.5% 3 hrs, larvae L3		313
Ethanol 5% 3 hrs, larvae L3		62
Ethanol 10% 3 hrs, larvae L3		81
Caffeine 1.5 mg/ml 4 hrs, larvae L3		31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		193
Caffeine 25 mg/ml 48 hrs, 4-day adult		88
Paraquat 5 mM 48 hrs, 4-day adult		179
Paraquat 10 mM 48 hrs, 4-day adult		181
Rotenone 2 μg 12 hrs, larvae L3		86
Rotenone 8 μg 12 hrs, larvae L3		97
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		(100)
cold shock, 4-day adult		(65)
heat shock, 4-day adult		(185)
Cadmium 50 mM 6 hrs, larvae L3		(96)
Cadmium 50 mM 12 hrs, larvae L3		(48)
Cadmium 50 mM 48 hrs, 4-day adult		(133)
Cadmium 100 mM 48 hrs, 4-day adult		(208)
Copper 0.5 mM 12 hrs, larvae L3		(58)
Copper 15 mM 48 hrs, 4-day adult		(153)
Zinc 5 mM 12 hrs, larvae L3		(46)
Zinc 4.5 mM 48 hrs, 4-day adult		(56)
Ethanol 2.5% 3 hrs, larvae L3		(313)
Ethanol 5% 3 hrs, larvae L3		(62)
Ethanol 10% 3 hrs, larvae L3		(81)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		(31)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(193)
Caffeine 25 mg/ml 48 hrs, 4-day adult		(88)
Paraquat 5 mM 48 hrs, 4-day adult		(179)
Paraquat 10 mM 48 hrs, 4-day adult		(181)
Rotenone 2 μg 12 hrs, larvae L3		(86)
Rotenone 8 μg 12 hrs, larvae L3		(97)
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		100
cold shock, 4-day adult		65
heat shock, 4-day adult		(185)
Cadmium 50 mM 6 hrs, larvae L3		96
Cadmium 50 mM 12 hrs, larvae L3		48
Cadmium 50 mM 48 hrs, 4-day adult		(133)
Cadmium 100 mM 48 hrs, 4-day adult		(208)
Copper 0.5 mM 12 hrs, larvae L3		58
Copper 15 mM 48 hrs, 4-day adult		(153)
Zinc 5 mM 12 hrs, larvae L3		46
Zinc 4.5 mM 48 hrs, 4-day adult		56
Ethanol 2.5% 3 hrs, larvae L3		(313)
Ethanol 5% 3 hrs, larvae L3		62
Ethanol 10% 3 hrs, larvae L3		81
Caffeine 1.5 mg/ml 4 hrs, larvae L3		31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(193)
Caffeine 25 mg/ml 48 hrs, 4-day adult		88
Paraquat 5 mM 48 hrs, 4-day adult		(179)
Paraquat 10 mM 48 hrs, 4-day adult		(181)
Rotenone 2 μg 12 hrs, larvae L3		86
Rotenone 8 μg 12 hrs, larvae L3		97
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		100
cold shock, 4-day adult		65
heat shock, 4-day adult		185
Cadmium 50 mM 6 hrs, larvae L3		96
Cadmium 50 mM 12 hrs, larvae L3		48
Cadmium 50 mM 48 hrs, 4-day adult		133
Cadmium 100 mM 48 hrs, 4-day adult		208
Copper 0.5 mM 12 hrs, larvae L3		58
Copper 15 mM 48 hrs, 4-day adult		153
Zinc 5 mM 12 hrs, larvae L3		46
Zinc 4.5 mM 48 hrs, 4-day adult		56
Ethanol 2.5% 3 hrs, larvae L3		313
Ethanol 5% 3 hrs, larvae L3		62
Ethanol 10% 3 hrs, larvae L3		81
Caffeine 1.5 mg/ml 4 hrs, larvae L3		31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		193
Caffeine 25 mg/ml 48 hrs, 4-day adult		88
Paraquat 5 mM 48 hrs, 4-day adult		179
Paraquat 10 mM 48 hrs, 4-day adult		181
Rotenone 2 μg 12 hrs, larvae L3		86
Rotenone 8 μg 12 hrs, larvae L3		97
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		100
cold shock, 4-day adult		65
heat shock, 4-day adult		185
Cadmium 50 mM 6 hrs, larvae L3		96
Cadmium 50 mM 12 hrs, larvae L3		48
Cadmium 50 mM 48 hrs, 4-day adult		133
Cadmium 100 mM 48 hrs, 4-day adult		208
Copper 0.5 mM 12 hrs, larvae L3		58
Copper 15 mM 48 hrs, 4-day adult		153
Zinc 5 mM 12 hrs, larvae L3		46
Zinc 4.5 mM 48 hrs, 4-day adult		56
Ethanol 2.5% 3 hrs, larvae L3		313
Ethanol 5% 3 hrs, larvae L3		62
Ethanol 10% 3 hrs, larvae L3		81
Caffeine 1.5 mg/ml 4 hrs, larvae L3		31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		193
Caffeine 25 mg/ml 48 hrs, 4-day adult		88
Paraquat 5 mM 48 hrs, 4-day adult		179
Paraquat 10 mM 48 hrs, 4-day adult		181
Rotenone 2 μg 12 hrs, larvae L3		86
Rotenone 8 μg 12 hrs, larvae L3		97
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		(100)
cold shock, 4-day adult		(65)
heat shock, 4-day adult		(185)
Cadmium 50 mM 6 hrs, larvae L3		(96)
Cadmium 50 mM 12 hrs, larvae L3		(48)
Cadmium 50 mM 48 hrs, 4-day adult		(133)
Cadmium 100 mM 48 hrs, 4-day adult		(208)
Copper 0.5 mM 12 hrs, larvae L3		(58)
Copper 15 mM 48 hrs, 4-day adult		(153)
Zinc 5 mM 12 hrs, larvae L3		(46)
Zinc 4.5 mM 48 hrs, 4-day adult		(56)
Ethanol 2.5% 3 hrs, larvae L3		(313)
Ethanol 5% 3 hrs, larvae L3		(62)
Ethanol 10% 3 hrs, larvae L3		(81)
Caffeine 1.5 mg/ml 4 hrs, larvae L3		31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(193)
Caffeine 25 mg/ml 48 hrs, 4-day adult		(88)
Paraquat 5 mM 48 hrs, 4-day adult		(179)
Paraquat 10 mM 48 hrs, 4-day adult		(181)
Rotenone 2 μg 12 hrs, larvae L3		(86)
Rotenone 8 μg 12 hrs, larvae L3		(97)
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		100
cold shock, 4-day adult		65
heat shock, 4-day adult		(185)
Cadmium 50 mM 6 hrs, larvae L3		96
Cadmium 50 mM 12 hrs, larvae L3		48
Cadmium 50 mM 48 hrs, 4-day adult		133
Cadmium 100 mM 48 hrs, 4-day adult		(208)
Copper 0.5 mM 12 hrs, larvae L3		58
Copper 15 mM 48 hrs, 4-day adult		(153)
Zinc 5 mM 12 hrs, larvae L3		46
Zinc 4.5 mM 48 hrs, 4-day adult		56
Ethanol 2.5% 3 hrs, larvae L3		(313)
Ethanol 5% 3 hrs, larvae L3		62
Ethanol 10% 3 hrs, larvae L3		81
Caffeine 1.5 mg/ml 4 hrs, larvae L3		31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		(193)
Caffeine 25 mg/ml 48 hrs, 4-day adult		88
Paraquat 5 mM 48 hrs, 4-day adult		(179)
Paraquat 10 mM 48 hrs, 4-day adult		(181)
Rotenone 2 μg 12 hrs, larvae L3		86
Rotenone 8 μg 12 hrs, larvae L3		97
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		100
cold shock, 4-day adult		65
heat shock, 4-day adult		185
Cadmium 50 mM 6 hrs, larvae L3		96
Cadmium 50 mM 12 hrs, larvae L3		48
Cadmium 50 mM 48 hrs, 4-day adult		133
Cadmium 100 mM 48 hrs, 4-day adult		208
Copper 0.5 mM 12 hrs, larvae L3		58
Copper 15 mM 48 hrs, 4-day adult		153
Zinc 5 mM 12 hrs, larvae L3		46
Zinc 4.5 mM 48 hrs, 4-day adult		56
Ethanol 2.5% 3 hrs, larvae L3		313
Ethanol 5% 3 hrs, larvae L3		62
Ethanol 10% 3 hrs, larvae L3		81
Caffeine 1.5 mg/ml 4 hrs, larvae L3		31
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		193
Caffeine 25 mg/ml 48 hrs, 4-day adult		88
Paraquat 5 mM 48 hrs, 4-day adult		179
Paraquat 10 mM 48 hrs, 4-day adult		181
Rotenone 2 μg 12 hrs, larvae L3		86
Rotenone 8 μg 12 hrs, larvae L3		97
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

BDGP expression data

•

SD02216

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0030086

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG7033-RC

FlyExpress - Embryonic expression images (BDGP data)

•

Show all FlyExpress processed images for CG7033

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

lethal

CG7033^GD5201

lethal, with Scer\GAL4^pnr-MD237

CG7033^GD5201

Other Phenotypes

Allele

neuroanatomy defective | larval stage

CG7033^GD5201

Phenotype manifest in

Allele

embryonic/larval neuroblast | larval stage

CG7033^GD5201

ganglion mother cell | larval stage

CG7033^GD5201

Classical Alleles ( 1 )

For All Classical Alleles Show

Allele of CG7033	Class	Mutagen	Stocks	Known lesion
CG7033^G11254		P-element activity	1	--

Alleles Carried on Transgenic Constructs ( 4 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG7033	Mutagen	Stocks	Known lesion
CG7033^GD5201	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG7033^HMS01190	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG7033^KK101795	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG7033^NIG.7033R	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes