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Gene Dmel\CG2972

General Information
Symbol	Dmel\CG2972	Species	D. melanogaster
Name		Annotation symbol	CG2972
Feature type	protein_coding_gene	FlyBase ID	FBgn0030177
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	9B1-9B1	Sequence location	X:9,977,203..9,978,875 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG2972 (FBgn0030177). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. There is experimental evidence that it is involved in the biological process: neurogenesis. 2 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has one annotated transcript and one annotated polypeptide. Protein features are: D-site 20S pre-rRNA nuclease; Nin one binding (NOB1) Zn-ribbon-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during early larval stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult ovary, adult male accessory gland. Comments on Affy2 ProbeSet: ProbeSet 1633322_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG2972. Gene sequence location is X:9977203..9978875.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN28208 HFA18250
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 9B1-9B1   Limits computationally determined from genome sequence between P{EP}nejEP1149&P{EP}nejEP1179 and P{EP}α-Man-IEP1628&P{EP}α-Man-IEP1307
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG2972 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.39
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG2972-RA FBtr0071430  NM_132375   1614   472
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG2972-PA   FBpp0071365   53.8   472   4.56     NP_572603   AAF46553
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Nin one binding (NOB1) Zn-ribbon-like (IPR014881) D-site 20S pre-rRNA nuclease (IPR017117)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA539649   AA978888   AE014298 AAF46553   AI405685   AW942460   AY119594 AAM50248   BF485883   BG638694   BI237110   BI354767   BI633981   BP548859   BP548860   CO313236   EC076583   EV585099   EV594058
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9W2Y4
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0030177    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0030177 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 00-06 hour embryonic stages, during early larval stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0030177 expression level Developmental Stage   Expression Level embryo 00-02hr    4206 embryo 02-04hr    1949 embryo 04-06hr    2509 embryo 06-08hr    3236 embryo 08-10hr    3163 embryo 10-12hr    3732 embryo 12-14hr    2323 embryo 14-16hr    1986 embryo 16-18hr    1469 embryo 18-20hr    1515 embryo 20-22hr    3216 embryo 22-24hr    2555 larva L1    4792 larva L2    2593 larva L3 12hr old    1630 larva L3 puffstage 1-2    817 larva L3 puffstage 3-6    949 larva L3 puffstage 7-9    964 white prepupae new    950 white prepupae 12hr    757 white prepupae 24hr    892 pupae 2d postWPP    957 pupae 3d postWPP    621 pupae 4d postWPP    664 adult male 01day    685 adult male 05day    826 adult male 30day    754 adult female 01day    2931 adult female 05day    3722 adult female 30day    4005 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4206) embryo 02-04hr  (1949) embryo 04-06hr  (2509) embryo 06-08hr  (3236) embryo 08-10hr  (3163) embryo 10-12hr  (3732) embryo 12-14hr  (2323) embryo 14-16hr  (1986) embryo 16-18hr  (1469) embryo 18-20hr  (1515) embryo 20-22hr  (3216) embryo 22-24hr  (2555) larva L1  (4792) larva L2  (2593) larva L3 12hr old  (1630) larva L3 puffstage 1-2  (817) larva L3 puffstage 3-6  (949) larva L3 puffstage 7-9  (964) white prepupae new  (950) white prepupae 12hr  (757) white prepupae 24hr  (892) pupae 2d postWPP  (957) pupae 3d postWPP  (621) pupae 4d postWPP  (664) adult male 01day  (685) adult male 05day  (826) adult male 30day  (754) adult female 01day  (2931) adult female 05day  (3722) adult female 30day  (4005) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4206) embryo 02-04hr  (1949) embryo 04-06hr  (2509) embryo 06-08hr  (3236) embryo 08-10hr  (3163) embryo 10-12hr  (3732) embryo 12-14hr  (2323) embryo 14-16hr  (1986) embryo 16-18hr  1469 embryo 18-20hr  (1515) embryo 20-22hr  (3216) embryo 22-24hr  (2555) larva L1  (4792) larva L2  (2593) larva L3 12hr old  (1630) larva L3 puffstage 1-2    817 larva L3 puffstage 3-6    949 larva L3 puffstage 7-9    964 white prepupae new    950 white prepupae 12hr    757 white prepupae 24hr    892 pupae 2d postWPP    957 pupae 3d postWPP    621 pupae 4d postWPP    664 adult male 01day    685 adult male 05day    826 adult male 30day    754 adult female 01day  (2931) adult female 05day  (3722) adult female 30day  (4005) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4206 embryo 02-04hr    1949 embryo 04-06hr    2509 embryo 06-08hr    3236 embryo 08-10hr    3163 embryo 10-12hr    3732 embryo 12-14hr    2323 embryo 14-16hr    1986 embryo 16-18hr    1469 embryo 18-20hr    1515 embryo 20-22hr    3216 embryo 22-24hr    2555 larva L1    4792 larva L2    2593 larva L3 12hr old    1630 larva L3 puffstage 1-2    817 larva L3 puffstage 3-6    949 larva L3 puffstage 7-9    964 white prepupae new    950 white prepupae 12hr    757 white prepupae 24hr    892 pupae 2d postWPP    957 pupae 3d postWPP    621 pupae 4d postWPP    664 adult male 01day    685 adult male 05day    826 adult male 30day    754 adult female 01day    2931 adult female 05day    3722 adult female 30day    4005 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4206 embryo 02-04hr    1949 embryo 04-06hr    2509 embryo 06-08hr    3236 embryo 08-10hr    3163 embryo 10-12hr    3732 embryo 12-14hr    2323 embryo 14-16hr    1986 embryo 16-18hr    1469 embryo 18-20hr    1515 embryo 20-22hr    3216 embryo 22-24hr    2555 larva L1    4792 larva L2    2593 larva L3 12hr old    1630 larva L3 puffstage 1-2    817 larva L3 puffstage 3-6    949 larva L3 puffstage 7-9    964 white prepupae new    950 white prepupae 12hr    757 white prepupae 24hr    892 pupae 2d postWPP    957 pupae 3d postWPP    621 pupae 4d postWPP    664 adult male 01day    685 adult male 05day    826 adult male 30day    754 adult female 01day    2931 adult female 05day    3722 adult female 30day    4005 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0030177 expression level Developmental Stage   Expression Level embryo 00-02hr    4206 embryo 02-04hr    1949 embryo 04-06hr    2509 embryo 06-08hr    3236 embryo 08-10hr    3163 embryo 10-12hr    3732 embryo 12-14hr    2323 embryo 14-16hr    1986 embryo 16-18hr    1469 embryo 18-20hr    1515 embryo 20-22hr    3216 embryo 22-24hr    2555 larva L1    4792 larva L2    2593 larva L3 12hr old    1630 larva L3 puffstage 1-2    817 larva L3 puffstage 3-6    949 larva L3 puffstage 7-9    964 white prepupae new    950 white prepupae 12hr    757 white prepupae 24hr    892 pupae 2d postWPP    957 pupae 3d postWPP    621 pupae 4d postWPP    664 adult male 01day    685 adult male 05day    826 adult male 30day    754 adult female 01day    2931 adult female 05day    3722 adult female 30day    4005 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (4206) embryo 02-04hr  (1949) embryo 04-06hr  (2509) embryo 06-08hr  (3236) embryo 08-10hr  (3163) embryo 10-12hr  (3732) embryo 12-14hr  (2323) embryo 14-16hr  (1986) embryo 16-18hr  (1469) embryo 18-20hr  (1515) embryo 20-22hr  (3216) embryo 22-24hr  (2555) larva L1  (4792) larva L2  (2593) larva L3 12hr old  (1630) larva L3 puffstage 1-2  (817) larva L3 puffstage 3-6  (949) larva L3 puffstage 7-9  (964) white prepupae new  (950) white prepupae 12hr  (757) white prepupae 24hr  (892) pupae 2d postWPP  (957) pupae 3d postWPP  (621) pupae 4d postWPP  (664) adult male 01day  (685) adult male 05day  (826) adult male 30day  (754) adult female 01day  (2931) adult female 05day  (3722) adult female 30day  (4005) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (4206) embryo 02-04hr  1949 embryo 04-06hr  (2509) embryo 06-08hr  (3236) embryo 08-10hr  (3163) embryo 10-12hr  (3732) embryo 12-14hr  2323 embryo 14-16hr  1986 embryo 16-18hr  1469 embryo 18-20hr  1515 embryo 20-22hr  (3216) embryo 22-24hr  (2555) larva L1  (4792) larva L2  (2593) larva L3 12hr old  1630 larva L3 puffstage 1-2    817 larva L3 puffstage 3-6    949 larva L3 puffstage 7-9    964 white prepupae new    950 white prepupae 12hr    757 white prepupae 24hr    892 pupae 2d postWPP    957 pupae 3d postWPP    621 pupae 4d postWPP    664 adult male 01day    685 adult male 05day    826 adult male 30day    754 adult female 01day  (2931) adult female 05day  (3722) adult female 30day  (4005) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    4206 embryo 02-04hr    1949 embryo 04-06hr    2509 embryo 06-08hr    3236 embryo 08-10hr    3163 embryo 10-12hr    3732 embryo 12-14hr    2323 embryo 14-16hr    1986 embryo 16-18hr    1469 embryo 18-20hr    1515 embryo 20-22hr    3216 embryo 22-24hr    2555 larva L1    4792 larva L2    2593 larva L3 12hr old    1630 larva L3 puffstage 1-2    817 larva L3 puffstage 3-6    949 larva L3 puffstage 7-9    964 white prepupae new    950 white prepupae 12hr    757 white prepupae 24hr    892 pupae 2d postWPP    957 pupae 3d postWPP    621 pupae 4d postWPP    664 adult male 01day    685 adult male 05day    826 adult male 30day    754 adult female 01day    2931 adult female 05day    3722 adult female 30day    4005 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    4206 embryo 02-04hr    1949 embryo 04-06hr    2509 embryo 06-08hr    3236 embryo 08-10hr    3163 embryo 10-12hr    3732 embryo 12-14hr    2323 embryo 14-16hr    1986 embryo 16-18hr    1469 embryo 18-20hr    1515 embryo 20-22hr    3216 embryo 22-24hr    2555 larva L1    4792 larva L2    2593 larva L3 12hr old    1630 larva L3 puffstage 1-2    817 larva L3 puffstage 3-6    949 larva L3 puffstage 7-9    964 white prepupae new    950 white prepupae 12hr    757 white prepupae 24hr    892 pupae 2d postWPP    957 pupae 3d postWPP    621 pupae 4d postWPP    664 adult male 01day    685 adult male 05day    826 adult male 30day    754 adult female 01day    2931 adult female 05day    3722 adult female 30day    4005 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0030177    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0030177 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system, adult ovary, adult male accessory gland. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0030177 expression level Tissue   Expression Level Larval Central Nervous System    103.675 Larval Midgut    52.7 Larval Hindgut    88.8 Larval Malpighian Tubules    44.4 Larval Fat Body    41.9 Larval Salivary Gland    91.9 Larval Trachea    89.9 Larval Carcass    74.275 Adult Head    51.1 Adult Eye    40.15 Adult Brain    36.4 Adult Thoracic-Abdominal Ganglion    40 Adult Crop    64.2 Adult Midgut    45.1 Adult Hindgut    54.4 Adult Malpighian Tubules    71.8 Adult Fat Body    97.7 Adult Salivary Gland    66 Adult Heart    48.625 Adult VirginFemale Spermatheca    68 Adult InseminatedFemale Spermatheca    89.5 Adult Ovary    222.1 Adult Testis    43.6 Adult Male Accessory Gland    116.1 Adult Carcass    52 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    103.675 Larval Midgut    52.7 Larval Hindgut    88.8 Larval Malpighian Tubules    44.4 Larval Fat Body    41.9 Larval Salivary Gland    91.9 Larval Trachea    89.9 Larval Carcass    74.275 Adult Head    51.1 Adult Eye    40.15 Adult Brain    36.4 Adult Thoracic-Abdominal Ganglion    40 Adult Crop    64.2 Adult Midgut    45.1 Adult Hindgut    54.4 Adult Malpighian Tubules    71.8 Adult Fat Body    97.7 Adult Salivary Gland    66 Adult Heart    48.625 Adult VirginFemale Spermatheca    68 Adult InseminatedFemale Spermatheca    89.5 Adult Ovary    222.1 Adult Testis    43.6 Adult Male Accessory Gland    116.1 Adult Carcass    52 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    103.675 Larval Midgut    52.7 Larval Hindgut    88.8 Larval Malpighian Tubules    44.4 Larval Fat Body    41.9 Larval Salivary Gland    91.9 Larval Trachea    89.9 Larval Carcass    74.275 Adult Head    51.1 Adult Eye    40.15 Adult Brain    36.4 Adult Thoracic-Abdominal Ganglion    40 Adult Crop    64.2 Adult Midgut    45.1 Adult Hindgut    54.4 Adult Malpighian Tubules    71.8 Adult Fat Body    97.7 Adult Salivary Gland    66 Adult Heart    48.625 Adult VirginFemale Spermatheca    68 Adult InseminatedFemale Spermatheca    89.5 Adult Ovary    222.1 Adult Testis    43.6 Adult Male Accessory Gland    116.1 Adult Carcass    52 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    103.675 Larval Midgut    52.7 Larval Hindgut    88.8 Larval Malpighian Tubules    44.4 Larval Fat Body    41.9 Larval Salivary Gland    91.9 Larval Trachea    89.9 Larval Carcass    74.275 Adult Head    51.1 Adult Eye    40.15 Adult Brain    36.4 Adult Thoracic-Abdominal Ganglion    40 Adult Crop    64.2 Adult Midgut    45.1 Adult Hindgut    54.4 Adult Malpighian Tubules    71.8 Adult Fat Body    97.7 Adult Salivary Gland    66 Adult Heart    48.625 Adult VirginFemale Spermatheca    68 Adult InseminatedFemale Spermatheca    89.5 Adult Ovary    222.1 Adult Testis    43.6 Adult Male Accessory Gland    116.1 Adult Carcass    52 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0030177 expression level Tissue   Expression Level Larval Central Nervous System    103.675 Larval Midgut    52.7 Larval Hindgut    88.8 Larval Malpighian Tubules    44.4 Larval Fat Body    41.9 Larval Salivary Gland    91.9 Larval Trachea    89.9 Larval Carcass    74.275 Adult Head    51.1 Adult Eye    40.15 Adult Brain    36.4 Adult Thoracic-Abdominal Ganglion    40 Adult Crop    64.2 Adult Midgut    45.1 Adult Hindgut    54.4 Adult Malpighian Tubules    71.8 Adult Fat Body    97.7 Adult Salivary Gland    66 Adult Heart    48.625 Adult VirginFemale Spermatheca    68 Adult InseminatedFemale Spermatheca    89.5 Adult Ovary    222.1 Adult Testis    43.6 Adult Male Accessory Gland    116.1 Adult Carcass    52 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    103.675 Larval Midgut    52.7 Larval Hindgut    88.8 Larval Malpighian Tubules    44.4 Larval Fat Body    41.9 Larval Salivary Gland    91.9 Larval Trachea    89.9 Larval Carcass    74.275 Adult Head    51.1 Adult Eye    40.15 Adult Brain    36.4 Adult Thoracic-Abdominal Ganglion    40 Adult Crop    64.2 Adult Midgut    45.1 Adult Hindgut    54.4 Adult Malpighian Tubules    71.8 Adult Fat Body    97.7 Adult Salivary Gland    66 Adult Heart    48.625 Adult VirginFemale Spermatheca    68 Adult InseminatedFemale Spermatheca    89.5 Adult Ovary    222.1 Adult Testis    43.6 Adult Male Accessory Gland    116.1 Adult Carcass    52 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    103.675 Larval Midgut    52.7 Larval Hindgut    88.8 Larval Malpighian Tubules    44.4 Larval Fat Body    41.9 Larval Salivary Gland    91.9 Larval Trachea    89.9 Larval Carcass    74.275 Adult Head    51.1 Adult Eye    40.15 Adult Brain    36.4 Adult Thoracic-Abdominal Ganglion    40 Adult Crop    64.2 Adult Midgut    45.1 Adult Hindgut    54.4 Adult Malpighian Tubules    71.8 Adult Fat Body    97.7 Adult Salivary Gland    66 Adult Heart    48.625 Adult VirginFemale Spermatheca    68 Adult InseminatedFemale Spermatheca    89.5 Adult Ovary    222.1 Adult Testis    43.6 Adult Male Accessory Gland    116.1 Adult Carcass    52 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    103.675 Larval Midgut    52.7 Larval Hindgut    88.8 Larval Malpighian Tubules    44.4 Larval Fat Body    41.9 Larval Salivary Gland    91.9 Larval Trachea    89.9 Larval Carcass    74.275 Adult Head    51.1 Adult Eye    40.15 Adult Brain    36.4 Adult Thoracic-Abdominal Ganglion    40 Adult Crop    64.2 Adult Midgut    45.1 Adult Hindgut    54.4 Adult Malpighian Tubules    71.8 Adult Fat Body    97.7 Adult Salivary Gland    66 Adult Heart    48.625 Adult VirginFemale Spermatheca    68 Adult InseminatedFemale Spermatheca    89.5 Adult Ovary    222.1 Adult Testis    43.6 Adult Male Accessory Gland    116.1 Adult Carcass    52 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    51.1   NA  Eye    40.15   NA  Brain    36.4   103.675  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    40   NA  Crop    64.2   52.7  Midgut    45.1   88.8  Hindgut    54.4   44.4  Malpighian Tubules    71.8   41.9  Fat Body    97.7   91.9  Salivary Gland    66   NA  Heart    48.625   89.9  Trachea    NA   NA  VirginFemale Spermatheca    68   NA  InseminatedFemale Spermatheca    89.5   NA  Ovary    222.1   NA  Testis    43.6   NA  Male Accessory Gland    116.1   74.275  Carcass    52 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_08
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030177 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG2972-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL41407 CG2972GD9870 semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 CG2972GD9870 Other Phenotypes Allele neuroanatomy defective | larval stage, with Scer\GAL41407 CG2972GD9870 visible, with Scer\GAL4pnr-MD237 CG2972GD9870 Phenotype manifest in Allele ganglion mother cell | larval stage, with Scer\GAL41407 CG2972GD9870 mesothoracic tergum, with Scer\GAL4pnr-MD237 CG2972GD9870 trichogen cell, with Scer\GAL4pnr-MD237 CG2972GD9870
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG2972 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG2972 Class Mutagen Stocks Known lesion CG2972GD9870 in vitro construct - RNAi in vitro construct - regulatory fusion 3 Yes CG2972KK108208 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD9870} NA P{KK108208} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
neurogenesis inferred from mutant phenotype (Neumüller et al., 2011)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG2972 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 58378 DroID - A comprehensive database of gene and protein interactions. • FBgn0030177 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31943
Orthologs
Genome-wide drosophilid orthologs	Dana\GF10341 Dere\GG18342 Dgri\GH12205 Dmoj\GI10936 Dpse\GA15547 Dsim\GD16972 Dvir\GJ18597 Dwil\GK25644 Dyak\GE17829
Curated drosophilid orthologs	Dpse\GA15547
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL005628-PB Aedes aegypti (mosquito) AGAP004064-PA Anopheles gambiae (mosquito) At5g41190.1 Arabidopsis thaliana (wall cress) 10084 Batrachochytrium dendrobatidis (chytrid fungus) 251138 Branchiostoma floridae (lancelet) BGIBMGA007192-PA Bombyx mori (silk worm) ENSBTAP00000027497 Bos taurus (bovine) CAL0000302 Candida albicans (a form of yeast) CN19907 Caenorhabditis brenneri (small nematode) CBP00972 Caenorhabditis briggsae (nematode) CE27481 Caenorhabditis elegans (worm) ENSCAFP00000030037 Canis familiaris (dog) CAGL0G01991g Candida glabrata (haploid yeast) Chro.70180 Cryptosporidium hominis (obligate parasite) CMJ120C Cyanidioschyzon merolae (red alga) cn01420 Cryptococcus neoformans (yeast-like fungus) cgd7_1530 Cryptosporidium parvum (protozoan parasite) CPIJ012739 Culex pipens (mosquito) ENSCPOP00000018403 Cavia porcellus (guinea pig) RP36828 Caenorhabditis remanei (nematode) ENSCSAVP00000015473 Ciona savignyi (sedentary tunicate) DDB0206310 Dictyostelium discoideum (amoeba) DEHA2D16258g Debaryomyces Hansenii (yeast) 301213 Daphnia pulex (daphnia) ENSDARP00000013936 Danio rerio (zebra fish) ENSECAP00000021281 Equus caballus (horse) XP_653279 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000023195 Gymnopilus aculeatus (mushroom) ENSGALP00000000975 Gallus gallus (chicken) GL50803_34141 Giardia lamblia (flagellated protozoan) 192032 Hypsipyla robusta (cedar shoot borer) ENSP00000268802 Homo sapiens (human) KLLA0F16280g Kluyveromyces lactis (yeast) 211535 Lottia gigantea (owl limpet) 34185 Monocosta brevicollis (choanoflagellate) ENSMODP00000003245 Monodelphis domestica (gray opossum) ENSMUSP00000003946 Mus musculus (house mouse) XP_001603318.1 Nasonia vitripennis (wasp) ENSORLP00000023551 Oryzias latipes (japanese killifish) LOC_Os02g02360.1 Oryza sativa (asian rice) 33578 Ostreococcus tauri (green alga) PFD0905w Plasmodium falciparum (protozoal parasite) PHUM001583-PA Pediculus humanus (human body louse) 233290 Physcomitrella patens (moss) ENSPPYP00000008479 Pongo pygmaeus (orangutan) 137056 Phytophthora sojae (root rot pathogen) 830830 Populus trichocarpa (black cottonwood) ENSPTRP00000014150 Pan troglodytes (chimpanzee) PVX_090025 Plasmodium vivax (protozoal parasite) ENSRNOP00000031905 Rattus norvegicus (norway rat) 144106 Sorghum bicolor (sorghum) YOR056C Saccharomyces cerevisiae (budding yeast) Smp_064510 Schistosoma mansoni (trematode parasite) SPAC1486.09 Schizosaccharomyces pombe (fission yeast) XP_001186723.1 Strongylocentrotus purpuratus (purple sea urchin) 4055 Trichoplax adhaerens (metazoa) XP_974124.1 Tribolium castaneum (red flour beetle) ENSTNIP00000005103 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000011401 Takifugu rubripes (pufferfish Takifugu) 21.m00336 Tetrahymena thermophila (ciliate protozoa) 85380.m00120 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000038743 Xenopus tropicalis (frog) YALI0F15829g Yarrowia lipolytica (nonconventional yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV13382 LH22344 ISCW022111 FBgn0235270 FBgn0227603 FBgn0205754 FBgn0188550 FBgn0166350 FBgn0166349 JGI_V11_301213 FBgn0075564 FBgn0153998 FBgn0153997 FBgn0133699 FBgn0119684 FBgn0110558 FBgn0087382 CPIJ012739 BGIBMGA007192 ACYPI000645 GB11728 AGAP004064 AAEL005628 PB22894 PHUM626370 GLEAN_13384
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
VDRC	v104991 P{KK108208}VIE-260B v20961 w1118 P{GD9870}v20961 v48771 w1118; P{GD9870}v48771 v48772 w1118; P{GD9870}v48772
Genomic Clones ( 1 )
	BACR07L06 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 12 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD17927
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT19957 GH25790 GM28211 RE33273 SD28207
Other clones	106411 Dmel_dig_016833_0626_0501 Dmel_neb_008991_0583_0638 EK231951 FGM002C02 LD33072
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030177 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31943
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132375 RefSeq (Proteins) • NP_572603 DDBJ / EMBL / GenBank • AA539649 AAF46553 AAM50248 AW942460 AY119594 Entrez Gene - A searchable database of RefSeq genes. • 31943 UniProtKB/TrEMBL • Q9W2Y4
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Nin one binding (NOB1) Zn-ribbon-like (IPR014881) D-site 20S pre-rRNA nuclease (IPR017117)
Linkouts
	BioGRID - A database of protein and genetic interactions • 58378 DroID - A comprehensive database of gene and protein interactions. • FBgn0030177 DRSC - Results from RNAi screens. • FBgn0030177 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030177 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG2972-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030177 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 31943 InParanoid A subset of ortholog calls from InParanoid. • AAEL005628-PB Aedes aegypti (mosquito) AGAP004064-PA Anopheles gambiae (mosquito) At5g41190.1 Arabidopsis thaliana (wall cress) 10084 Batrachochytrium dendrobatidis (chytrid fungus) 251138 Branchiostoma floridae (lancelet) BGIBMGA007192-PA Bombyx mori (silk worm) ENSBTAP00000027497 Bos taurus (bovine) CAL0000302 Candida albicans (a form of yeast) CN19907 Caenorhabditis brenneri (small nematode) CBP00972 Caenorhabditis briggsae (nematode) CE27481 Caenorhabditis elegans (worm) ENSCAFP00000030037 Canis familiaris (dog) CAGL0G01991g Candida glabrata (haploid yeast) Chro.70180 Cryptosporidium hominis (obligate parasite) CMJ120C Cyanidioschyzon merolae (red alga) cn01420 Cryptococcus neoformans (yeast-like fungus) cgd7_1530 Cryptosporidium parvum (protozoan parasite) CPIJ012739 Culex pipens (mosquito) ENSCPOP00000018403 Cavia porcellus (guinea pig) RP36828 Caenorhabditis remanei (nematode) ENSCSAVP00000015473 Ciona savignyi (sedentary tunicate) DDB0206310 Dictyostelium discoideum (amoeba) DEHA2D16258g Debaryomyces Hansenii (yeast) 301213 Daphnia pulex (daphnia) ENSDARP00000013936 Danio rerio (zebra fish) ENSECAP00000021281 Equus caballus (horse) XP_653279 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000023195 Gymnopilus aculeatus (mushroom) ENSGALP00000000975 Gallus gallus (chicken) GL50803_34141 Giardia lamblia (flagellated protozoan) 192032 Hypsipyla robusta (cedar shoot borer) ENSP00000268802 Homo sapiens (human) KLLA0F16280g Kluyveromyces lactis (yeast) 211535 Lottia gigantea (owl limpet) 34185 Monocosta brevicollis (choanoflagellate) ENSMODP00000003245 Monodelphis domestica (gray opossum) ENSMUSP00000003946 Mus musculus (house mouse) XP_001603318.1 Nasonia vitripennis (wasp) ENSORLP00000023551 Oryzias latipes (japanese killifish) LOC_Os02g02360.1 Oryza sativa (asian rice) 33578 Ostreococcus tauri (green alga) PFD0905w Plasmodium falciparum (protozoal parasite) PHUM001583-PA Pediculus humanus (human body louse) 233290 Physcomitrella patens (moss) ENSPPYP00000008479 Pongo pygmaeus (orangutan) 137056 Phytophthora sojae (root rot pathogen) 830830 Populus trichocarpa (black cottonwood) ENSPTRP00000014150 Pan troglodytes (chimpanzee) PVX_090025 Plasmodium vivax (protozoal parasite) ENSRNOP00000031905 Rattus norvegicus (norway rat) 144106 Sorghum bicolor (sorghum) YOR056C Saccharomyces cerevisiae (budding yeast) Smp_064510 Schistosoma mansoni (trematode parasite) SPAC1486.09 Schizosaccharomyces pombe (fission yeast) XP_001186723.1 Strongylocentrotus purpuratus (purple sea urchin) 4055 Trichoplax adhaerens (metazoa) XP_974124.1 Tribolium castaneum (red flour beetle) ENSTNIP00000005103 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000011401 Takifugu rubripes (pufferfish Takifugu) 21.m00336 Tetrahymena thermophila (ciliate protozoa) 85380.m00120 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000038743 Xenopus tropicalis (frog) YALI0F15829g Yarrowia lipolytica (nonconventional yeast) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 31943 modMine - Data generated by the modENCODE project. • FBgn0030177 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV13382 LH22344 ISCW022111 FBgn0235270 FBgn0227603 FBgn0205754 FBgn0188550 FBgn0166350 FBgn0166349 JGI_V11_301213 FBgn0075564 FBgn0153998 FBgn0153997 FBgn0133699 FBgn0119684 FBgn0110558 FBgn0087382 CPIJ012739 BGIBMGA007192 ACYPI000645 GB11728 AGAP004064 AAEL005628 PB22894 PHUM626370 GLEAN_13384
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG2972 (Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 8 )
Supplementary material	Neumüller et al., 2011, Cell Stem Cell 8(5): Supplemental Table S1. [FBrf0214431] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]