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Gene Dmel\CG11699

General Information
Symbol	Dmel\CG11699	Species	D. melanogaster
Name		Annotation symbol	CG11699
Feature type	protein_coding_gene	FlyBase ID	FBgn0030311
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	10C6-10C6	Sequence location	X:11,464,654..11,465,443 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG11699 (FBgn0030311). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 5 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Protein of unknown function DUF1358. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, larval midgut, larval hindgut, adult heart, larval/adult salivary gland, larval trachea, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult midgut, adult hindgut, larval/adult Malpighian tubules, larval/adult fat body, adult female reproductive system, adult male accessory gland, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1638275_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG11699. Gene sequence location is X:11464654..11465443.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 10C6-10C6
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG11699 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Low-frequency RNA-Seq exon junction(s) not annotated. Gene model reviewed during 5.45
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG11699-RA FBtr0073510  NM_132500   640   146
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG11699-PA   FBpp0073359   15.8   146   9.82     NP_572728   AAF48058
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Protein of unknown function DUF1358 (IPR009792)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF48058   AI402365   AY071552 AAL49174   BE977682   BI374258   BI374558   BI570170   BI592848   BI592865   BP551069   BP559677   BP559678   CL527841   CO278272   CO323990   EC198645   GH740072   GH740160   GH744062   GH744331   GH763528   GH763727   GH764490   GH765236   GH768264
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VYX5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 4 -- 6   organism   (Fisher et al., 2012) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 9 -- 10   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 13 -- 16   organism | ubiquitous   (Fisher et al., 2012)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, adult crop, larval midgut, larval hindgut, adult heart, larval/adult salivary gland, larval trachea, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult midgut, adult hindgut, larval/adult Malpighian tubules, larval/adult fat body, adult female reproductive system, adult male accessory gland, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    515.625 Larval Midgut    502 Larval Hindgut    646 Larval Malpighian Tubules    484.5 Larval Fat Body    422.9 Larval Salivary Gland    854.9 Larval Trachea    594.7 Larval Carcass    594.35 Adult Head    344.7 Adult Eye    368.95 Adult Brain    393.9 Adult Thoracic-Abdominal Ganglion    372.9 Adult Crop    509.5 Adult Midgut    297.3 Adult Hindgut    392.9 Adult Malpighian Tubules    246.4 Adult Fat Body    432.6 Adult Salivary Gland    833.3 Adult Heart    657.125 Adult VirginFemale Spermatheca    248.8 Adult InseminatedFemale Spermatheca    267.4 Adult Ovary    357.9 Adult Testis    74.2 Adult Male Accessory Gland    426.1 Adult Carcass    471.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  515.625 Larval Midgut  502 Larval Hindgut  (646) Larval Malpighian Tubules    484.5 Larval Fat Body    422.9 Larval Salivary Gland  (854.9) Larval Trachea  (594.7) Larval Carcass  (594.35) Adult Head    344.7 Adult Eye    368.95 Adult Brain    393.9 Adult Thoracic-Abdominal Ganglion    372.9 Adult Crop  509.5 Adult Midgut    297.3 Adult Hindgut    392.9 Adult Malpighian Tubules    246.4 Adult Fat Body    432.6 Adult Salivary Gland  (833.3) Adult Heart  (657.125) Adult VirginFemale Spermatheca    248.8 Adult InseminatedFemale Spermatheca    267.4 Adult Ovary    357.9 Adult Testis    74.2 Adult Male Accessory Gland    426.1 Adult Carcass    471.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    515.625 Larval Midgut    502 Larval Hindgut    646 Larval Malpighian Tubules    484.5 Larval Fat Body    422.9 Larval Salivary Gland    854.9 Larval Trachea    594.7 Larval Carcass    594.35 Adult Head    344.7 Adult Eye    368.95 Adult Brain    393.9 Adult Thoracic-Abdominal Ganglion    372.9 Adult Crop    509.5 Adult Midgut    297.3 Adult Hindgut    392.9 Adult Malpighian Tubules    246.4 Adult Fat Body    432.6 Adult Salivary Gland    833.3 Adult Heart    657.125 Adult VirginFemale Spermatheca    248.8 Adult InseminatedFemale Spermatheca    267.4 Adult Ovary    357.9 Adult Testis    74.2 Adult Male Accessory Gland    426.1 Adult Carcass    471.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    515.625 Larval Midgut    502 Larval Hindgut    646 Larval Malpighian Tubules    484.5 Larval Fat Body    422.9 Larval Salivary Gland    854.9 Larval Trachea    594.7 Larval Carcass    594.35 Adult Head    344.7 Adult Eye    368.95 Adult Brain    393.9 Adult Thoracic-Abdominal Ganglion    372.9 Adult Crop    509.5 Adult Midgut    297.3 Adult Hindgut    392.9 Adult Malpighian Tubules    246.4 Adult Fat Body    432.6 Adult Salivary Gland    833.3 Adult Heart    657.125 Adult VirginFemale Spermatheca    248.8 Adult InseminatedFemale Spermatheca    267.4 Adult Ovary    357.9 Adult Testis    74.2 Adult Male Accessory Gland    426.1 Adult Carcass    471.5 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    515.625 Larval Midgut    502 Larval Hindgut    646 Larval Malpighian Tubules    484.5 Larval Fat Body    422.9 Larval Salivary Gland    854.9 Larval Trachea    594.7 Larval Carcass    594.35 Adult Head    344.7 Adult Eye    368.95 Adult Brain    393.9 Adult Thoracic-Abdominal Ganglion    372.9 Adult Crop    509.5 Adult Midgut    297.3 Adult Hindgut    392.9 Adult Malpighian Tubules    246.4 Adult Fat Body    432.6 Adult Salivary Gland    833.3 Adult Heart    657.125 Adult VirginFemale Spermatheca    248.8 Adult InseminatedFemale Spermatheca    267.4 Adult Ovary    357.9 Adult Testis    74.2 Adult Male Accessory Gland    426.1 Adult Carcass    471.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  515.625 Larval Midgut  502 Larval Hindgut  646 Larval Malpighian Tubules    484.5 Larval Fat Body    422.9 Larval Salivary Gland  (854.9) Larval Trachea  594.7 Larval Carcass  594.35 Adult Head    344.7 Adult Eye    368.95 Adult Brain    393.9 Adult Thoracic-Abdominal Ganglion    372.9 Adult Crop  509.5 Adult Midgut    297.3 Adult Hindgut    392.9 Adult Malpighian Tubules    246.4 Adult Fat Body    432.6 Adult Salivary Gland  (833.3) Adult Heart  657.125 Adult VirginFemale Spermatheca    248.8 Adult InseminatedFemale Spermatheca    267.4 Adult Ovary    357.9 Adult Testis    74.2 Adult Male Accessory Gland    426.1 Adult Carcass    471.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    515.625 Larval Midgut    502 Larval Hindgut    646 Larval Malpighian Tubules    484.5 Larval Fat Body    422.9 Larval Salivary Gland    854.9 Larval Trachea    594.7 Larval Carcass    594.35 Adult Head    344.7 Adult Eye    368.95 Adult Brain    393.9 Adult Thoracic-Abdominal Ganglion    372.9 Adult Crop    509.5 Adult Midgut    297.3 Adult Hindgut    392.9 Adult Malpighian Tubules    246.4 Adult Fat Body    432.6 Adult Salivary Gland    833.3 Adult Heart    657.125 Adult VirginFemale Spermatheca    248.8 Adult InseminatedFemale Spermatheca    267.4 Adult Ovary    357.9 Adult Testis    74.2 Adult Male Accessory Gland    426.1 Adult Carcass    471.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    515.625 Larval Midgut    502 Larval Hindgut    646 Larval Malpighian Tubules    484.5 Larval Fat Body    422.9 Larval Salivary Gland    854.9 Larval Trachea    594.7 Larval Carcass    594.35 Adult Head    344.7 Adult Eye    368.95 Adult Brain    393.9 Adult Thoracic-Abdominal Ganglion    372.9 Adult Crop    509.5 Adult Midgut    297.3 Adult Hindgut    392.9 Adult Malpighian Tubules    246.4 Adult Fat Body    432.6 Adult Salivary Gland    833.3 Adult Heart    657.125 Adult VirginFemale Spermatheca    248.8 Adult InseminatedFemale Spermatheca    267.4 Adult Ovary    357.9 Adult Testis    74.2 Adult Male Accessory Gland    426.1 Adult Carcass    471.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    344.7   NA  Eye    368.95   NA  Brain    393.9   515.625  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    372.9   NA  Crop    509.5   502  Midgut    297.3   646  Hindgut    392.9   484.5  Malpighian Tubules    246.4   422.9  Fat Body    432.6   854.9  Salivary Gland    833.3   NA  Heart    657.125   594.7  Trachea    NA   NA  VirginFemale Spermatheca    248.8   NA  InseminatedFemale Spermatheca    267.4   NA  Ovary    357.9   NA  Testis    74.2   NA  Male Accessory Gland    426.1   594.35  Carcass    471.5 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    87 central nervous system, larvae L3    90 central nervous system, pupae P8    71 head, virgin 1-day female    92 head, virgin 4-day female    74 head, virgin 20-day female    35 head, mated 1-day female    85 head, mated 4-day female    62 head, mated 20-day female    44 head, mated 1-day male    90 head, mated 4-day male    76 head, mated 20-day male    81 salivary gland, larvae L3 wandering    58 salivary gland, white prepupae    35 digestive system, larvae L3 wandering    106 digestive system, 1-day adult    102 digestive system, 4-day adult    86 digestive system, 20-day adult    70 fat body, larvae L3 wandering    62 fat body, white prepupae    48 fat body, pupae P8    162 carcass, larvae L3 wandering    85 carcass, 1-day adult    147 carcass, 4-day adult    92 carcass, 20-day adult    68 ovary, virgin 4-day female    83 ovary, mated 4-day female    91 testis, mated 4-day male    67 accessory gland, mated 4-day male    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (87) central nervous system, larvae L3  (90) central nervous system, pupae P8  (71) head, virgin 1-day female  (92) head, virgin 4-day female  (74) head, virgin 20-day female  (35) head, mated 1-day female  (85) head, mated 4-day female  (62) head, mated 20-day female  (44) head, mated 1-day male  (90) head, mated 4-day male  (76) head, mated 20-day male  (81) salivary gland, larvae L3 wandering  (58) salivary gland, white prepupae  (35) digestive system, larvae L3 wandering  (106) digestive system, 1-day adult  (102) digestive system, 4-day adult  (86) digestive system, 20-day adult  (70) fat body, larvae L3 wandering  (62) fat body, white prepupae  (48) fat body, pupae P8  (162) carcass, larvae L3 wandering  (85) carcass, 1-day adult  (147) carcass, 4-day adult  (92) carcass, 20-day adult  (68) ovary, virgin 4-day female  (83) ovary, mated 4-day female  (91) testis, mated 4-day male  (67) accessory gland, mated 4-day male  (93) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    87 central nervous system, larvae L3    90 central nervous system, pupae P8    71 head, virgin 1-day female    92 head, virgin 4-day female    74 head, virgin 20-day female    35 head, mated 1-day female    85 head, mated 4-day female    62 head, mated 20-day female    44 head, mated 1-day male    90 head, mated 4-day male    76 head, mated 20-day male    81 salivary gland, larvae L3 wandering    58 salivary gland, white prepupae    35 digestive system, larvae L3 wandering  106 digestive system, 1-day adult  102 digestive system, 4-day adult    86 digestive system, 20-day adult    70 fat body, larvae L3 wandering    62 fat body, white prepupae    48 fat body, pupae P8  (162) carcass, larvae L3 wandering    85 carcass, 1-day adult  (147) carcass, 4-day adult    92 carcass, 20-day adult    68 ovary, virgin 4-day female    83 ovary, mated 4-day female    91 testis, mated 4-day male    67 accessory gland, mated 4-day male    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    87 central nervous system, larvae L3    90 central nervous system, pupae P8    71 head, virgin 1-day female    92 head, virgin 4-day female    74 head, virgin 20-day female    35 head, mated 1-day female    85 head, mated 4-day female    62 head, mated 20-day female    44 head, mated 1-day male    90 head, mated 4-day male    76 head, mated 20-day male    81 salivary gland, larvae L3 wandering    58 salivary gland, white prepupae    35 digestive system, larvae L3 wandering    106 digestive system, 1-day adult    102 digestive system, 4-day adult    86 digestive system, 20-day adult    70 fat body, larvae L3 wandering    62 fat body, white prepupae    48 fat body, pupae P8    162 carcass, larvae L3 wandering    85 carcass, 1-day adult    147 carcass, 4-day adult    92 carcass, 20-day adult    68 ovary, virgin 4-day female    83 ovary, mated 4-day female    91 testis, mated 4-day male    67 accessory gland, mated 4-day male    93 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    87 central nervous system, larvae L3    90 central nervous system, pupae P8    71 head, virgin 1-day female    92 head, virgin 4-day female    74 head, virgin 20-day female    35 head, mated 1-day female    85 head, mated 4-day female    62 head, mated 20-day female    44 head, mated 1-day male    90 head, mated 4-day male    76 head, mated 20-day male    81 salivary gland, larvae L3 wandering    58 salivary gland, white prepupae    35 digestive system, larvae L3 wandering    106 digestive system, 1-day adult    102 digestive system, 4-day adult    86 digestive system, 20-day adult    70 fat body, larvae L3 wandering    62 fat body, white prepupae    48 fat body, pupae P8    162 carcass, larvae L3 wandering    85 carcass, 1-day adult    147 carcass, 4-day adult    92 carcass, 20-day adult    68 ovary, virgin 4-day female    83 ovary, mated 4-day female    91 testis, mated 4-day male    67 accessory gland, mated 4-day male    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (87) central nervous system, larvae L3  (90) central nervous system, pupae P8  (71) head, virgin 1-day female  (92) head, virgin 4-day female  (74) head, virgin 20-day female  (35) head, mated 1-day female  (85) head, mated 4-day female  (62) head, mated 20-day female  (44) head, mated 1-day male  (90) head, mated 4-day male  (76) head, mated 20-day male  (81) salivary gland, larvae L3 wandering  (58) salivary gland, white prepupae  (35) digestive system, larvae L3 wandering  (106) digestive system, 1-day adult  (102) digestive system, 4-day adult  (86) digestive system, 20-day adult  (70) fat body, larvae L3 wandering  (62) fat body, white prepupae  (48) fat body, pupae P8  (162) carcass, larvae L3 wandering  (85) carcass, 1-day adult  (147) carcass, 4-day adult  (92) carcass, 20-day adult  (68) ovary, virgin 4-day female  (83) ovary, mated 4-day female  (91) testis, mated 4-day male  (67) accessory gland, mated 4-day male  (93) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    87 central nervous system, larvae L3    90 central nervous system, pupae P8    71 head, virgin 1-day female    92 head, virgin 4-day female    74 head, virgin 20-day female    35 head, mated 1-day female    85 head, mated 4-day female    62 head, mated 20-day female    44 head, mated 1-day male    90 head, mated 4-day male    76 head, mated 20-day male    81 salivary gland, larvae L3 wandering    58 salivary gland, white prepupae    35 digestive system, larvae L3 wandering  106 digestive system, 1-day adult  102 digestive system, 4-day adult    86 digestive system, 20-day adult    70 fat body, larvae L3 wandering    62 fat body, white prepupae    48 fat body, pupae P8  (162) carcass, larvae L3 wandering    85 carcass, 1-day adult  (147) carcass, 4-day adult    92 carcass, 20-day adult    68 ovary, virgin 4-day female    83 ovary, mated 4-day female    91 testis, mated 4-day male    67 accessory gland, mated 4-day male    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    87 central nervous system, larvae L3    90 central nervous system, pupae P8    71 head, virgin 1-day female    92 head, virgin 4-day female    74 head, virgin 20-day female    35 head, mated 1-day female    85 head, mated 4-day female    62 head, mated 20-day female    44 head, mated 1-day male    90 head, mated 4-day male    76 head, mated 20-day male    81 salivary gland, larvae L3 wandering    58 salivary gland, white prepupae    35 digestive system, larvae L3 wandering    106 digestive system, 1-day adult    102 digestive system, 4-day adult    86 digestive system, 20-day adult    70 fat body, larvae L3 wandering    62 fat body, white prepupae    48 fat body, pupae P8    162 carcass, larvae L3 wandering    85 carcass, 1-day adult    147 carcass, 4-day adult    92 carcass, 20-day adult    68 ovary, virgin 4-day female    83 ovary, mated 4-day female    91 testis, mated 4-day male    67 accessory gland, mated 4-day male    93 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 06-12 hour embryonic stages, at stages throughout the larval period, during late pupal stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    17 embryo 02-04hr    8 embryo 04-06hr    26 embryo 06-08hr    32 embryo 08-10hr    34 embryo 10-12hr    35 embryo 12-14hr    35 embryo 14-16hr    16 embryo 16-18hr    26 embryo 18-20hr    13 embryo 20-22hr    18 embryo 22-24hr    31 larva L1    29 larva L2    43 larva L3 12hr old    30 larva L3 puffstage 1-2    36 larva L3 puffstage 3-6    26 larva L3 puffstage 7-9    28 white prepupae new    24 white prepupae 12hr    26 white prepupae 24hr    26 pupae 2d postWPP    36 pupae 3d postWPP    57 pupae 4d postWPP    30 adult male 01day    41 adult male 05day    30 adult male 30day    18 adult female 01day    29 adult female 05day    36 adult female 30day    37 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    17 embryo 02-04hr    8 embryo 04-06hr  26 embryo 06-08hr  (32) embryo 08-10hr  (34) embryo 10-12hr  (35) embryo 12-14hr  (35) embryo 14-16hr    16 embryo 16-18hr  26 embryo 18-20hr    13 embryo 20-22hr    18 embryo 22-24hr  (31) larva L1  (29) larva L2  (43) larva L3 12hr old  (30) larva L3 puffstage 1-2  (36) larva L3 puffstage 3-6  26 larva L3 puffstage 7-9  (28) white prepupae new    24 white prepupae 12hr  26 white prepupae 24hr  26 pupae 2d postWPP  (36) pupae 3d postWPP  (57) pupae 4d postWPP  (30) adult male 01day  (41) adult male 05day  (30) adult male 30day    18 adult female 01day  (29) adult female 05day  (36) adult female 30day  (37) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    17 embryo 02-04hr    8 embryo 04-06hr    26 embryo 06-08hr    32 embryo 08-10hr    34 embryo 10-12hr    35 embryo 12-14hr    35 embryo 14-16hr    16 embryo 16-18hr    26 embryo 18-20hr    13 embryo 20-22hr    18 embryo 22-24hr    31 larva L1    29 larva L2    43 larva L3 12hr old    30 larva L3 puffstage 1-2    36 larva L3 puffstage 3-6    26 larva L3 puffstage 7-9    28 white prepupae new    24 white prepupae 12hr    26 white prepupae 24hr    26 pupae 2d postWPP    36 pupae 3d postWPP    57 pupae 4d postWPP    30 adult male 01day    41 adult male 05day    30 adult male 30day    18 adult female 01day    29 adult female 05day    36 adult female 30day    37 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    17 embryo 02-04hr    8 embryo 04-06hr    26 embryo 06-08hr    32 embryo 08-10hr    34 embryo 10-12hr    35 embryo 12-14hr    35 embryo 14-16hr    16 embryo 16-18hr    26 embryo 18-20hr    13 embryo 20-22hr    18 embryo 22-24hr    31 larva L1    29 larva L2    43 larva L3 12hr old    30 larva L3 puffstage 1-2    36 larva L3 puffstage 3-6    26 larva L3 puffstage 7-9    28 white prepupae new    24 white prepupae 12hr    26 white prepupae 24hr    26 pupae 2d postWPP    36 pupae 3d postWPP    57 pupae 4d postWPP    30 adult male 01day    41 adult male 05day    30 adult male 30day    18 adult female 01day    29 adult female 05day    36 adult female 30day    37 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    17 embryo 02-04hr    8 embryo 04-06hr    26 embryo 06-08hr    32 embryo 08-10hr    34 embryo 10-12hr    35 embryo 12-14hr    35 embryo 14-16hr    16 embryo 16-18hr    26 embryo 18-20hr    13 embryo 20-22hr    18 embryo 22-24hr    31 larva L1    29 larva L2    43 larva L3 12hr old    30 larva L3 puffstage 1-2    36 larva L3 puffstage 3-6    26 larva L3 puffstage 7-9    28 white prepupae new    24 white prepupae 12hr    26 white prepupae 24hr    26 pupae 2d postWPP    36 pupae 3d postWPP    57 pupae 4d postWPP    30 adult male 01day    41 adult male 05day    30 adult male 30day    18 adult female 01day    29 adult female 05day    36 adult female 30day    37 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    17 embryo 02-04hr    8 embryo 04-06hr  26 embryo 06-08hr  32 embryo 08-10hr  (34) embryo 10-12hr  (35) embryo 12-14hr  (35) embryo 14-16hr    16 embryo 16-18hr  26 embryo 18-20hr    13 embryo 20-22hr    18 embryo 22-24hr  31 larva L1  29 larva L2  (43) larva L3 12hr old  30 larva L3 puffstage 1-2  (36) larva L3 puffstage 3-6  26 larva L3 puffstage 7-9  28 white prepupae new    24 white prepupae 12hr  26 white prepupae 24hr  26 pupae 2d postWPP  (36) pupae 3d postWPP  (57) pupae 4d postWPP  30 adult male 01day  (41) adult male 05day  30 adult male 30day    18 adult female 01day  29 adult female 05day  (36) adult female 30day  (37) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    17 embryo 02-04hr    8 embryo 04-06hr    26 embryo 06-08hr    32 embryo 08-10hr    34 embryo 10-12hr    35 embryo 12-14hr    35 embryo 14-16hr    16 embryo 16-18hr    26 embryo 18-20hr    13 embryo 20-22hr    18 embryo 22-24hr    31 larva L1    29 larva L2    43 larva L3 12hr old    30 larva L3 puffstage 1-2    36 larva L3 puffstage 3-6    26 larva L3 puffstage 7-9    28 white prepupae new    24 white prepupae 12hr    26 white prepupae 24hr    26 pupae 2d postWPP    36 pupae 3d postWPP    57 pupae 4d postWPP    30 adult male 01day    41 adult male 05day    30 adult male 30day    18 adult female 01day    29 adult female 05day    36 adult female 30day    37 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    17 embryo 02-04hr    8 embryo 04-06hr    26 embryo 06-08hr    32 embryo 08-10hr    34 embryo 10-12hr    35 embryo 12-14hr    35 embryo 14-16hr    16 embryo 16-18hr    26 embryo 18-20hr    13 embryo 20-22hr    18 embryo 22-24hr    31 larva L1    29 larva L2    43 larva L3 12hr old    30 larva L3 puffstage 1-2    36 larva L3 puffstage 3-6    26 larva L3 puffstage 7-9    28 white prepupae new    24 white prepupae 12hr    26 white prepupae 24hr    26 pupae 2d postWPP    36 pupae 3d postWPP    57 pupae 4d postWPP    30 adult male 01day    41 adult male 05day    30 adult male 30day    18 adult female 01day    29 adult female 05day    36 adult female 30day    37 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    159 Schneider line 2 Sg4    77 embryonic 1182-4H    187 embryonic GM2    101 embryonic Kc167    71 embryonic S1    137 embryonic S3    110 leg disc CME L1    110 wing disc CME-W2    80 wing disc ML-DmD8    136 wing disc ML-DmD9    204 wing disc ML-DmD16-c3    125 wing disc ML-DmD21    257 wing disc ML-DmD32    227 haltere disc ML-DmD17-c3    80 eye-antennal disc ML-DmD11    307 antennal disc ML-DmD20-c5    146 mixed discs ML-DmD4-c1    141 CNS ML-DmBG1-c1    245 CNS ML-DmBG2-c2    80 tumorous blood cells mbn2    103 ovary fGS/OSS    100 ovary OSC    102 ovary OSS    61 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (159) Schneider line 2 Sg4  (77) embryonic 1182-4H  (187) embryonic GM2  (101) embryonic Kc167  (71) embryonic S1  (137) embryonic S3  (110) leg disc CME L1  (110) wing disc CME-W2  (80) wing disc ML-DmD8  (136) wing disc ML-DmD9  (204) wing disc ML-DmD16-c3  (125) wing disc ML-DmD21  (257) wing disc ML-DmD32  (227) haltere disc ML-DmD17-c3  (80) eye-antennal disc ML-DmD11  (307) antennal disc ML-DmD20-c5  (146) mixed discs ML-DmD4-c1  (141) CNS ML-DmBG1-c1  (245) CNS ML-DmBG2-c2  (80) tumorous blood cells mbn2  (103) ovary fGS/OSS  (100) ovary OSC  (102) ovary OSS  (61) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (159) Schneider line 2 Sg4    77 embryonic 1182-4H  (187) embryonic GM2  101 embryonic Kc167    71 embryonic S1  (137) embryonic S3  (110) leg disc CME L1  (110) wing disc CME-W2    80 wing disc ML-DmD8  (136) wing disc ML-DmD9  (204) wing disc ML-DmD16-c3  (125) wing disc ML-DmD21  (257) wing disc ML-DmD32  (227) haltere disc ML-DmD17-c3    80 eye-antennal disc ML-DmD11  (307) antennal disc ML-DmD20-c5  (146) mixed discs ML-DmD4-c1  (141) CNS ML-DmBG1-c1  (245) CNS ML-DmBG2-c2    80 tumorous blood cells mbn2  103 ovary fGS/OSS    100 ovary OSC  102 ovary OSS    61 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    159 Schneider line 2 Sg4    77 embryonic 1182-4H    187 embryonic GM2    101 embryonic Kc167    71 embryonic S1    137 embryonic S3    110 leg disc CME L1    110 wing disc CME-W2    80 wing disc ML-DmD8    136 wing disc ML-DmD9    204 wing disc ML-DmD16-c3    125 wing disc ML-DmD21    257 wing disc ML-DmD32    227 haltere disc ML-DmD17-c3    80 eye-antennal disc ML-DmD11    307 antennal disc ML-DmD20-c5    146 mixed discs ML-DmD4-c1    141 CNS ML-DmBG1-c1    245 CNS ML-DmBG2-c2    80 tumorous blood cells mbn2    103 ovary fGS/OSS    100 ovary OSC    102 ovary OSS    61 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    159 Schneider line 2 Sg4    77 embryonic 1182-4H    187 embryonic GM2    101 embryonic Kc167    71 embryonic S1    137 embryonic S3    110 leg disc CME L1    110 wing disc CME-W2    80 wing disc ML-DmD8    136 wing disc ML-DmD9    204 wing disc ML-DmD16-c3    125 wing disc ML-DmD21    257 wing disc ML-DmD32    227 haltere disc ML-DmD17-c3    80 eye-antennal disc ML-DmD11    307 antennal disc ML-DmD20-c5    146 mixed discs ML-DmD4-c1    141 CNS ML-DmBG1-c1    245 CNS ML-DmBG2-c2    80 tumorous blood cells mbn2    103 ovary fGS/OSS    100 ovary OSC    102 ovary OSS    61 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (159) Schneider line 2 Sg4  (77) embryonic 1182-4H  (187) embryonic GM2  (101) embryonic Kc167  (71) embryonic S1  (137) embryonic S3  (110) leg disc CME L1  (110) wing disc CME-W2  (80) wing disc ML-DmD8  (136) wing disc ML-DmD9  (204) wing disc ML-DmD16-c3  (125) wing disc ML-DmD21  (257) wing disc ML-DmD32  (227) haltere disc ML-DmD17-c3  (80) eye-antennal disc ML-DmD11  (307) antennal disc ML-DmD20-c5  (146) mixed discs ML-DmD4-c1  (141) CNS ML-DmBG1-c1  (245) CNS ML-DmBG2-c2  (80) tumorous blood cells mbn2  (103) ovary fGS/OSS  (100) ovary OSC  (102) ovary OSS  (61) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (159) Schneider line 2 Sg4    77 embryonic 1182-4H  (187) embryonic GM2  101 embryonic Kc167    71 embryonic S1  137 embryonic S3  110 leg disc CME L1  110 wing disc CME-W2    80 wing disc ML-DmD8  136 wing disc ML-DmD9  (204) wing disc ML-DmD16-c3  125 wing disc ML-DmD21  (257) wing disc ML-DmD32  (227) haltere disc ML-DmD17-c3    80 eye-antennal disc ML-DmD11  (307) antennal disc ML-DmD20-c5  (146) mixed discs ML-DmD4-c1  141 CNS ML-DmBG1-c1  (245) CNS ML-DmBG2-c2    80 tumorous blood cells mbn2  103 ovary fGS/OSS    100 ovary OSC  102 ovary OSS    61 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    159 Schneider line 2 Sg4    77 embryonic 1182-4H    187 embryonic GM2    101 embryonic Kc167    71 embryonic S1    137 embryonic S3    110 leg disc CME L1    110 wing disc CME-W2    80 wing disc ML-DmD8    136 wing disc ML-DmD9    204 wing disc ML-DmD16-c3    125 wing disc ML-DmD21    257 wing disc ML-DmD32    227 haltere disc ML-DmD17-c3    80 eye-antennal disc ML-DmD11    307 antennal disc ML-DmD20-c5    146 mixed discs ML-DmD4-c1    141 CNS ML-DmBG1-c1    245 CNS ML-DmBG2-c2    80 tumorous blood cells mbn2    103 ovary fGS/OSS    100 ovary OSC    102 ovary OSS    61 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    51 cold shock, 4-day adult    50 heat shock, 4-day adult    82 Cadmium 50 mM 6 hrs, larvae L3    97 Cadmium 50 mM 12 hrs, larvae L3    114 Cadmium 50 mM 48 hrs, 4-day adult    91 Cadmium 100 mM 48 hrs, 4-day adult    92 Copper 0.5 mM 12 hrs, larvae L3    67 Copper 15 mM 48 hrs, 4-day adult    100 Zinc 5 mM 12 hrs, larvae L3    83 Zinc 4.5 mM 48 hrs, 4-day adult    94 Ethanol 2.5% 3 hrs, larvae L3    74 Ethanol 5% 3 hrs, larvae L3    121 Ethanol 10% 3 hrs, larvae L3    95 Caffeine 1.5 mg/ml 4 hrs, larvae L3    112 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    97 Caffeine 25 mg/ml 48 hrs, 4-day adult    43 Paraquat 5 mM 48 hrs, 4-day adult    106 Paraquat 10 mM 48 hrs, 4-day adult    85 Rotenone 2 μg 12 hrs, larvae L3    113 Rotenone 8 μg 12 hrs, larvae L3    99 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (51) cold shock, 4-day adult  (50) heat shock, 4-day adult  (82) Cadmium 50 mM 6 hrs, larvae L3  (97) Cadmium 50 mM 12 hrs, larvae L3  (114) Cadmium 50 mM 48 hrs, 4-day adult  (91) Cadmium 100 mM 48 hrs, 4-day adult  (92) Copper 0.5 mM 12 hrs, larvae L3  (67) Copper 15 mM 48 hrs, 4-day adult  (100) Zinc 5 mM 12 hrs, larvae L3  (83) Zinc 4.5 mM 48 hrs, 4-day adult  (94) Ethanol 2.5% 3 hrs, larvae L3  (74) Ethanol 5% 3 hrs, larvae L3  (121) Ethanol 10% 3 hrs, larvae L3  (95) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (112) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (97) Caffeine 25 mg/ml 48 hrs, 4-day adult  (43) Paraquat 5 mM 48 hrs, 4-day adult  (106) Paraquat 10 mM 48 hrs, 4-day adult  (85) Rotenone 2 μg 12 hrs, larvae L3  (113) Rotenone 8 μg 12 hrs, larvae L3  (99) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    51 cold shock, 4-day adult    50 heat shock, 4-day adult    82 Cadmium 50 mM 6 hrs, larvae L3    97 Cadmium 50 mM 12 hrs, larvae L3  (114) Cadmium 50 mM 48 hrs, 4-day adult    91 Cadmium 100 mM 48 hrs, 4-day adult    92 Copper 0.5 mM 12 hrs, larvae L3    67 Copper 15 mM 48 hrs, 4-day adult    100 Zinc 5 mM 12 hrs, larvae L3    83 Zinc 4.5 mM 48 hrs, 4-day adult    94 Ethanol 2.5% 3 hrs, larvae L3    74 Ethanol 5% 3 hrs, larvae L3  (121) Ethanol 10% 3 hrs, larvae L3    95 Caffeine 1.5 mg/ml 4 hrs, larvae L3  (112) Caffeine 2.5 mg/ml 48 hrs, 4-day adult    97 Caffeine 25 mg/ml 48 hrs, 4-day adult    43 Paraquat 5 mM 48 hrs, 4-day adult  106 Paraquat 10 mM 48 hrs, 4-day adult    85 Rotenone 2 μg 12 hrs, larvae L3  (113) Rotenone 8 μg 12 hrs, larvae L3    99 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    51 cold shock, 4-day adult    50 heat shock, 4-day adult    82 Cadmium 50 mM 6 hrs, larvae L3    97 Cadmium 50 mM 12 hrs, larvae L3    114 Cadmium 50 mM 48 hrs, 4-day adult    91 Cadmium 100 mM 48 hrs, 4-day adult    92 Copper 0.5 mM 12 hrs, larvae L3    67 Copper 15 mM 48 hrs, 4-day adult    100 Zinc 5 mM 12 hrs, larvae L3    83 Zinc 4.5 mM 48 hrs, 4-day adult    94 Ethanol 2.5% 3 hrs, larvae L3    74 Ethanol 5% 3 hrs, larvae L3    121 Ethanol 10% 3 hrs, larvae L3    95 Caffeine 1.5 mg/ml 4 hrs, larvae L3    112 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    97 Caffeine 25 mg/ml 48 hrs, 4-day adult    43 Paraquat 5 mM 48 hrs, 4-day adult    106 Paraquat 10 mM 48 hrs, 4-day adult    85 Rotenone 2 μg 12 hrs, larvae L3    113 Rotenone 8 μg 12 hrs, larvae L3    99 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    51 cold shock, 4-day adult    50 heat shock, 4-day adult    82 Cadmium 50 mM 6 hrs, larvae L3    97 Cadmium 50 mM 12 hrs, larvae L3    114 Cadmium 50 mM 48 hrs, 4-day adult    91 Cadmium 100 mM 48 hrs, 4-day adult    92 Copper 0.5 mM 12 hrs, larvae L3    67 Copper 15 mM 48 hrs, 4-day adult    100 Zinc 5 mM 12 hrs, larvae L3    83 Zinc 4.5 mM 48 hrs, 4-day adult    94 Ethanol 2.5% 3 hrs, larvae L3    74 Ethanol 5% 3 hrs, larvae L3    121 Ethanol 10% 3 hrs, larvae L3    95 Caffeine 1.5 mg/ml 4 hrs, larvae L3    112 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    97 Caffeine 25 mg/ml 48 hrs, 4-day adult    43 Paraquat 5 mM 48 hrs, 4-day adult    106 Paraquat 10 mM 48 hrs, 4-day adult    85 Rotenone 2 μg 12 hrs, larvae L3    113 Rotenone 8 μg 12 hrs, larvae L3    99 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (51) cold shock, 4-day adult  (50) heat shock, 4-day adult  (82) Cadmium 50 mM 6 hrs, larvae L3  (97) Cadmium 50 mM 12 hrs, larvae L3  (114) Cadmium 50 mM 48 hrs, 4-day adult  (91) Cadmium 100 mM 48 hrs, 4-day adult  (92) Copper 0.5 mM 12 hrs, larvae L3  (67) Copper 15 mM 48 hrs, 4-day adult  (100) Zinc 5 mM 12 hrs, larvae L3  (83) Zinc 4.5 mM 48 hrs, 4-day adult  (94) Ethanol 2.5% 3 hrs, larvae L3  (74) Ethanol 5% 3 hrs, larvae L3  (121) Ethanol 10% 3 hrs, larvae L3  (95) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (112) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (97) Caffeine 25 mg/ml 48 hrs, 4-day adult  (43) Paraquat 5 mM 48 hrs, 4-day adult  (106) Paraquat 10 mM 48 hrs, 4-day adult  (85) Rotenone 2 μg 12 hrs, larvae L3  (113) Rotenone 8 μg 12 hrs, larvae L3  (99) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    51 cold shock, 4-day adult    50 heat shock, 4-day adult    82 Cadmium 50 mM 6 hrs, larvae L3    97 Cadmium 50 mM 12 hrs, larvae L3  114 Cadmium 50 mM 48 hrs, 4-day adult    91 Cadmium 100 mM 48 hrs, 4-day adult    92 Copper 0.5 mM 12 hrs, larvae L3    67 Copper 15 mM 48 hrs, 4-day adult    100 Zinc 5 mM 12 hrs, larvae L3    83 Zinc 4.5 mM 48 hrs, 4-day adult    94 Ethanol 2.5% 3 hrs, larvae L3    74 Ethanol 5% 3 hrs, larvae L3  121 Ethanol 10% 3 hrs, larvae L3    95 Caffeine 1.5 mg/ml 4 hrs, larvae L3  112 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    97 Caffeine 25 mg/ml 48 hrs, 4-day adult    43 Paraquat 5 mM 48 hrs, 4-day adult  106 Paraquat 10 mM 48 hrs, 4-day adult    85 Rotenone 2 μg 12 hrs, larvae L3  113 Rotenone 8 μg 12 hrs, larvae L3    99 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    51 cold shock, 4-day adult    50 heat shock, 4-day adult    82 Cadmium 50 mM 6 hrs, larvae L3    97 Cadmium 50 mM 12 hrs, larvae L3    114 Cadmium 50 mM 48 hrs, 4-day adult    91 Cadmium 100 mM 48 hrs, 4-day adult    92 Copper 0.5 mM 12 hrs, larvae L3    67 Copper 15 mM 48 hrs, 4-day adult    100 Zinc 5 mM 12 hrs, larvae L3    83 Zinc 4.5 mM 48 hrs, 4-day adult    94 Ethanol 2.5% 3 hrs, larvae L3    74 Ethanol 5% 3 hrs, larvae L3    121 Ethanol 10% 3 hrs, larvae L3    95 Caffeine 1.5 mg/ml 4 hrs, larvae L3    112 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    97 Caffeine 25 mg/ml 48 hrs, 4-day adult    43 Paraquat 5 mM 48 hrs, 4-day adult    106 Paraquat 10 mM 48 hrs, 4-day adult    85 Rotenone 2 μg 12 hrs, larvae L3    113 Rotenone 8 μg 12 hrs, larvae L3    99 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_09 mE1_20_mRNA_expression_cluster_03
External Data & Images
Linkouts	BDGP expression data • RE61805 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030311 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11699-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG11699EY05909 viable, with Scer\GAL4pnr-MD237 CG11699GD4014 Sterility Allele fertile CG11699EY05909 Other Phenotypes Allele behavior defective CG11699EY05909 chemical sensitive CG11699EY05909 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG11699 Class Mutagen Stocks Known lesion CG11699EY05909 P-element activity 1 -- CG11699EP1556 P-element activity 0 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG11699 Class Mutagen Stocks Known lesion CG11699GD4014 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG11699KK108854 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG11699NIG.11699R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4014} NA P{KK108854} NA P{NIG.11699R} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}CG11699EP1556 NA P{EPgy2}CG11699EY05909 NA miscellaneous insertions PBac{RB}Kmn1e01118 NA
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG11699 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 58511 DroID - A comprehensive database of gene and protein interactions. • FBgn0030311 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32101
Orthologs
OrthoDB Orthologs (38) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG615H11 Dipteran inclusive ortholog search EOG6894WV Insect inclusive ortholog search EOG6GF2BS Arthropod inclusive ortholog search EOG67M0FF Metazoa inclusive ortholog search EOG63FVTG
Orthologs in Drosophila Species (EOG615H11)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG11699     Drosophila simulans   Dsim\GD17031 Y   Drosophila sechellia   Dsec\GM13091 Y   Drosophila erecta   Dere\GG18427 Y   Drosophila yakuba   Dyak\GE15945 Y   Drosophila ananassae   Dana\GF20319 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA11150 Y   Drosophila persimilis   Dper\GL26739 Y   Drosophila willistoni   Dwil\GK16295 Y   Drosophila virilis   Dvir\GJ15629 Y   Drosophila mojavensis   Dmoj\GI16053 Y   Drosophila grimshawi   Dgri\GH17914 Y
Orthologs in non-Drosophila Dipterans (EOG6894WV)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL010544   Aedes aegypti Yellow fever mosquito  Aaeg\AAEL003270   Anopheles gambiae Malaria mosquito  Agam\AGAP009165   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ015673
Orthologs in non-Dipteran Insects (EOG6GF2BS)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\LOC552237   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG014848   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH15293   Atta cephalotes Leafcutter ant  Acep\ACEP16604   Camponotus floridanus Florida carpenter ant  Cflo\CFLO20991   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL15535   Linepithema humile Argentine ant  Lhum\LH12727   Pogonomyrmex barbatus Red harvester ant  Pbar\PB12639   Solenopsis invicta Red fire ant  Sinv\SINV21581   Acyrthosiphon pisum Pea aphid  Apim\ACYPI004866   Pediculus humanus Human body louse  Phum\PHUM602100   Tribolium castaneum Red flour beetle  Tcas\TC013211
Orthologs in non-Insect Arthropods (EOG67M0FF)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_243398   Daphnia pulex Water flea  Dpux\JGI_V11_226107   Ixodes scapularis Deer tick  Isca\ISCW002507
Orthologs in non-Arthropod Metazoa (EOG63FVTG)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_001044gn   Danio rerio Zebrafish  Drer\ENSDARG00000037070   Xenopus tropicalis Western clawed frog  Xtro\tmem242   Gallus gallus Domestic chicken  Ggal\C6orf35   Mus musculus House mouse  Mmus\ENSMUSG00000004945   Rattus norvegicus Norway rat  Rnor\LOC100362950   Homo sapiens Human  Hsap\TMEM242
Human Orthologs (1)
Gene OMIM HGNC Hsap\TMEM242
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD17031 Drosophila sechellia Dsec\GM13091 Drosophila erecta Dere\GG18427 Drosophila yakuba Dyak\GE15945 Drosophila ananassae Dana\GF20319 Drosophila pseudoobscura pseudoobscura Dpse\GA11150 Drosophila persimilis Dper\GL26739 Drosophila willistoni Dwil\GK16295 Drosophila virilis Dvir\GJ15629 Drosophila mojavensis Dmoj\GI16053 Drosophila grimshawi Dgri\GH17914
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	16374 y1 w67c23 P{EPgy2}CG11699EY05909
VDRC	v101491 P{KK108854}VIE-260B v15861 w1118; P{GD4014}v15861
Genomic Clones ( 1 )
	BACR26B05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 21 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE61805
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH21565 RE62182 RH10635 RH10664
Other clones	17342 bs67f11 EK129615 EK192209 FGM210G06 FGM322C06 RH02444 RP001004920 RP001006520 RP001008094 RP001012735 RP001025175 RP001026765 RP001046785 RP001048824 RP001050092
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030311 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32101
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132500 RefSeq (Proteins) • NP_572728 DDBJ / EMBL / GenBank • AAF48058 AAL49174 AY071552 BI374258 CL527841 Entrez Gene - A searchable database of RefSeq genes. • 32101 UniProtKB/TrEMBL • Q9VYX5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Protein of unknown function DUF1358 (IPR009792) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • RE61805
Linkouts
	BioGRID - A database of protein and genetic interactions • 58511 DroID - A comprehensive database of gene and protein interactions. • FBgn0030311 DRSC - Results from RNAi screens. • FBgn0030311 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030311 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11699-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030311 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32101 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32101 modMine - Data generated by the modENCODE project. • FBgn0030311
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG11699 (Drnevich et al., 2004, Arthaud et al., 2011, González et al., 2008, Straub et al., 2008, Keleman et al., 2009.8.5, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym
Secondary FlyBase IDs
References ( 15 )
Research paper	Arthaud et al., 2011, PLoS ONE 6(5): e19805 Trade-Off between Toxicity and Signal Detection Orchestrated by Frequency- and Density-Dependent Genes. [FBrf0213771] González et al., 2008, PLoS Biol. 6(10): e251 High rate of recent transposable element-induced adaptation in Drosophila melanogaster. [FBrf0206197] Straub et al., 2008, PLoS Genet. 4(12): e1000302 The chromosomal high-affinity binding sites for the Drosophila dosage compensation complex. [FBrf0206582] Drnevich et al., 2004, Proc. Biol. Sci. 271(1554): 2267--2273 Quantitative evolutionary genomics: differential gene expression and male reproductive success in Drosophila melanogaster. [FBrf0180658]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Gene Disruption Project members, 2001-, (Computer file) (Computer file) [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]
Website	Fisher et al., 2012, BDGP insitu homepage BDGP insitu homepage [FBrf0219073]