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Gene Dmel\CG1840

General Information
Symbol	Dmel\CG1840	Species	D. melanogaster
Name		Annotation symbol	CG1840
Feature type	protein_coding_gene	FlyBase ID	FBgn0030351
Gene Model Status	Current	Stock availability	1 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	10F4-10F4	Sequence location	X:11,782,385..11,783,219 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG1840 (FBgn0030351). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Selenoprotein SelK/SelG. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 06-18 hour embryonic stages, at stages throughout the pupal period. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult heart, larval/adult salivary gland, larval trachea, adult male reproductive system. Comments on Affy2 ProbeSet: ProbeSet 1636902_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG1840. Gene sequence location is X:11782385..11783219.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 10F4-10F4   Limits computationally determined from genome sequence between P{EP}ATP7EP308 and P{EP}EP1451&P{EP}EP1629
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG1840 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.45 Gene model reviewed during 5.49
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG1840-RA FBtr0073571  NM_132536   719   118 CG1840-RB FBtr0331590  NM_001272545   716   117
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG1840-PA   FBpp0073415   11.8   118   10.86     NP_572764   AAF48112 CG1840-PB   FBpp0303980   11.7   117   10.86     NP_001259474   AGB95317
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Selenoprotein SelK/SelG (IPR024491)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA440936   AE014298 AAF48112   AE014298 AGB95317   AI406237   AW942246   AY094783 AAM11136   BI216615   CO296577   EC061522   EC209917   EC247654
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VYS6
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult heart, larval/adult salivary gland, larval trachea, adult male reproductive system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    71.325 Larval Midgut    36.2 Larval Hindgut    34.7 Larval Malpighian Tubules    82.7 Larval Fat Body    78.8 Larval Salivary Gland    111.7 Larval Trachea    125.5 Larval Carcass    45.15 Adult Head    66.4 Adult Eye    81.975 Adult Brain    92.1 Adult Thoracic-Abdominal Ganglion    81.6 Adult Crop    74.8 Adult Midgut    81 Adult Hindgut    60 Adult Malpighian Tubules    69.7 Adult Fat Body    55.5 Adult Salivary Gland    105.3 Adult Heart    135.675 Adult VirginFemale Spermatheca    33.2 Adult InseminatedFemale Spermatheca    44.3 Adult Ovary    77.2 Adult Testis    127.6 Adult Male Accessory Gland    113.3 Adult Carcass    54.6 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    71.325 Larval Midgut    36.2 Larval Hindgut    34.7 Larval Malpighian Tubules    82.7 Larval Fat Body    78.8 Larval Salivary Gland    111.7 Larval Trachea    125.5 Larval Carcass    45.15 Adult Head    66.4 Adult Eye    81.975 Adult Brain    92.1 Adult Thoracic-Abdominal Ganglion    81.6 Adult Crop    74.8 Adult Midgut    81 Adult Hindgut    60 Adult Malpighian Tubules    69.7 Adult Fat Body    55.5 Adult Salivary Gland    105.3 Adult Heart    135.675 Adult VirginFemale Spermatheca    33.2 Adult InseminatedFemale Spermatheca    44.3 Adult Ovary    77.2 Adult Testis    127.6 Adult Male Accessory Gland    113.3 Adult Carcass    54.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    71.325 Larval Midgut    36.2 Larval Hindgut    34.7 Larval Malpighian Tubules    82.7 Larval Fat Body    78.8 Larval Salivary Gland    111.7 Larval Trachea    125.5 Larval Carcass    45.15 Adult Head    66.4 Adult Eye    81.975 Adult Brain    92.1 Adult Thoracic-Abdominal Ganglion    81.6 Adult Crop    74.8 Adult Midgut    81 Adult Hindgut    60 Adult Malpighian Tubules    69.7 Adult Fat Body    55.5 Adult Salivary Gland    105.3 Adult Heart    135.675 Adult VirginFemale Spermatheca    33.2 Adult InseminatedFemale Spermatheca    44.3 Adult Ovary    77.2 Adult Testis    127.6 Adult Male Accessory Gland    113.3 Adult Carcass    54.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    71.325 Larval Midgut    36.2 Larval Hindgut    34.7 Larval Malpighian Tubules    82.7 Larval Fat Body    78.8 Larval Salivary Gland    111.7 Larval Trachea    125.5 Larval Carcass    45.15 Adult Head    66.4 Adult Eye    81.975 Adult Brain    92.1 Adult Thoracic-Abdominal Ganglion    81.6 Adult Crop    74.8 Adult Midgut    81 Adult Hindgut    60 Adult Malpighian Tubules    69.7 Adult Fat Body    55.5 Adult Salivary Gland    105.3 Adult Heart    135.675 Adult VirginFemale Spermatheca    33.2 Adult InseminatedFemale Spermatheca    44.3 Adult Ovary    77.2 Adult Testis    127.6 Adult Male Accessory Gland    113.3 Adult Carcass    54.6 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    71.325 Larval Midgut    36.2 Larval Hindgut    34.7 Larval Malpighian Tubules    82.7 Larval Fat Body    78.8 Larval Salivary Gland    111.7 Larval Trachea    125.5 Larval Carcass    45.15 Adult Head    66.4 Adult Eye    81.975 Adult Brain    92.1 Adult Thoracic-Abdominal Ganglion    81.6 Adult Crop    74.8 Adult Midgut    81 Adult Hindgut    60 Adult Malpighian Tubules    69.7 Adult Fat Body    55.5 Adult Salivary Gland    105.3 Adult Heart    135.675 Adult VirginFemale Spermatheca    33.2 Adult InseminatedFemale Spermatheca    44.3 Adult Ovary    77.2 Adult Testis    127.6 Adult Male Accessory Gland    113.3 Adult Carcass    54.6 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    71.325 Larval Midgut    36.2 Larval Hindgut    34.7 Larval Malpighian Tubules    82.7 Larval Fat Body    78.8 Larval Salivary Gland    111.7 Larval Trachea    125.5 Larval Carcass    45.15 Adult Head    66.4 Adult Eye    81.975 Adult Brain    92.1 Adult Thoracic-Abdominal Ganglion    81.6 Adult Crop    74.8 Adult Midgut    81 Adult Hindgut    60 Adult Malpighian Tubules    69.7 Adult Fat Body    55.5 Adult Salivary Gland    105.3 Adult Heart    135.675 Adult VirginFemale Spermatheca    33.2 Adult InseminatedFemale Spermatheca    44.3 Adult Ovary    77.2 Adult Testis    127.6 Adult Male Accessory Gland    113.3 Adult Carcass    54.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    71.325 Larval Midgut    36.2 Larval Hindgut    34.7 Larval Malpighian Tubules    82.7 Larval Fat Body    78.8 Larval Salivary Gland    111.7 Larval Trachea    125.5 Larval Carcass    45.15 Adult Head    66.4 Adult Eye    81.975 Adult Brain    92.1 Adult Thoracic-Abdominal Ganglion    81.6 Adult Crop    74.8 Adult Midgut    81 Adult Hindgut    60 Adult Malpighian Tubules    69.7 Adult Fat Body    55.5 Adult Salivary Gland    105.3 Adult Heart    135.675 Adult VirginFemale Spermatheca    33.2 Adult InseminatedFemale Spermatheca    44.3 Adult Ovary    77.2 Adult Testis    127.6 Adult Male Accessory Gland    113.3 Adult Carcass    54.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    71.325 Larval Midgut    36.2 Larval Hindgut    34.7 Larval Malpighian Tubules    82.7 Larval Fat Body    78.8 Larval Salivary Gland    111.7 Larval Trachea    125.5 Larval Carcass    45.15 Adult Head    66.4 Adult Eye    81.975 Adult Brain    92.1 Adult Thoracic-Abdominal Ganglion    81.6 Adult Crop    74.8 Adult Midgut    81 Adult Hindgut    60 Adult Malpighian Tubules    69.7 Adult Fat Body    55.5 Adult Salivary Gland    105.3 Adult Heart    135.675 Adult VirginFemale Spermatheca    33.2 Adult InseminatedFemale Spermatheca    44.3 Adult Ovary    77.2 Adult Testis    127.6 Adult Male Accessory Gland    113.3 Adult Carcass    54.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    66.4   NA  Eye    81.975   NA  Brain    92.1   71.325  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    81.6   NA  Crop    74.8   36.2  Midgut    81   34.7  Hindgut    60   82.7  Malpighian Tubules    69.7   78.8  Fat Body    55.5   111.7  Salivary Gland    105.3   NA  Heart    135.675   125.5  Trachea    NA   NA  VirginFemale Spermatheca    33.2   NA  InseminatedFemale Spermatheca    44.3   NA  Ovary    77.2   NA  Testis    127.6   NA  Male Accessory Gland    113.3   45.15  Carcass    54.6 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    5 central nervous system, larvae L3    2 central nervous system, pupae P8    4 head, virgin 1-day female    3 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    2 head, mated 4-day female    2 head, mated 20-day female    2 head, mated 1-day male    3 head, mated 4-day male    3 head, mated 20-day male    2 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    4 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    2 fat body, pupae P8    3 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    1 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    8 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    5 central nervous system, larvae L3    2 central nervous system, pupae P8    4 head, virgin 1-day female    3 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    2 head, mated 4-day female    2 head, mated 20-day female    2 head, mated 1-day male    3 head, mated 4-day male    3 head, mated 20-day male    2 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    4 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    2 fat body, pupae P8    3 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    1 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    8 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    5 central nervous system, larvae L3    2 central nervous system, pupae P8    4 head, virgin 1-day female    3 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    2 head, mated 4-day female    2 head, mated 20-day female    2 head, mated 1-day male    3 head, mated 4-day male    3 head, mated 20-day male    2 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    4 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    2 fat body, pupae P8    3 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    1 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    8 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    5 central nervous system, larvae L3    2 central nervous system, pupae P8    4 head, virgin 1-day female    3 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    2 head, mated 4-day female    2 head, mated 20-day female    2 head, mated 1-day male    3 head, mated 4-day male    3 head, mated 20-day male    2 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    4 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    2 fat body, pupae P8    3 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    1 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    8 accessory gland, mated 4-day male    3 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    5 central nervous system, larvae L3    2 central nervous system, pupae P8    4 head, virgin 1-day female    3 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    2 head, mated 4-day female    2 head, mated 20-day female    2 head, mated 1-day male    3 head, mated 4-day male    3 head, mated 20-day male    2 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    4 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    2 fat body, pupae P8    3 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    1 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    8 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    5 central nervous system, larvae L3    2 central nervous system, pupae P8    4 head, virgin 1-day female    3 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    2 head, mated 4-day female    2 head, mated 20-day female    2 head, mated 1-day male    3 head, mated 4-day male    3 head, mated 20-day male    2 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    4 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    2 fat body, pupae P8    3 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    1 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    8 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    5 central nervous system, larvae L3    2 central nervous system, pupae P8    4 head, virgin 1-day female    3 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    2 head, mated 4-day female    2 head, mated 20-day female    2 head, mated 1-day male    3 head, mated 4-day male    3 head, mated 20-day male    2 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    4 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    2 fat body, pupae P8    3 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    1 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    8 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    5 central nervous system, larvae L3    2 central nervous system, pupae P8    4 head, virgin 1-day female    3 head, virgin 4-day female    2 head, virgin 20-day female    1 head, mated 1-day female    2 head, mated 4-day female    2 head, mated 20-day female    2 head, mated 1-day male    3 head, mated 4-day male    3 head, mated 20-day male    2 salivary gland, larvae L3 wandering    6 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    1 digestive system, 1-day adult    4 digestive system, 4-day adult    2 digestive system, 20-day adult    2 fat body, larvae L3 wandering    1 fat body, white prepupae    2 fat body, pupae P8    3 carcass, larvae L3 wandering    2 carcass, 1-day adult    1 carcass, 4-day adult    2 carcass, 20-day adult    1 ovary, virgin 4-day female    5 ovary, mated 4-day female    5 testis, mated 4-day male    8 accessory gland, mated 4-day male    3 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed within 06-18 hour embryonic stages, at stages throughout the pupal period. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    13 embryo 02-04hr    13 embryo 04-06hr    10 embryo 06-08hr    20 embryo 08-10hr    20 embryo 10-12hr    27 embryo 12-14hr    30 embryo 14-16hr    23 embryo 16-18hr    21 embryo 18-20hr    11 embryo 20-22hr    9 embryo 22-24hr    12 larva L1    9 larva L2    15 larva L3 12hr old    9 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    11 white prepupae new    16 white prepupae 12hr    13 white prepupae 24hr    18 pupae 2d postWPP    22 pupae 3d postWPP    14 pupae 4d postWPP    7 adult male 01day    11 adult male 05day    13 adult male 30day    13 adult female 01day    6 adult female 05day    13 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    13 embryo 02-04hr    13 embryo 04-06hr    10 embryo 06-08hr    20 embryo 08-10hr    20 embryo 10-12hr  (27) embryo 12-14hr  (30) embryo 14-16hr    23 embryo 16-18hr    21 embryo 18-20hr    11 embryo 20-22hr    9 embryo 22-24hr    12 larva L1    9 larva L2    15 larva L3 12hr old    9 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    11 white prepupae new    16 white prepupae 12hr    13 white prepupae 24hr    18 pupae 2d postWPP    22 pupae 3d postWPP    14 pupae 4d postWPP    7 adult male 01day    11 adult male 05day    13 adult male 30day    13 adult female 01day    6 adult female 05day    13 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    13 embryo 02-04hr    13 embryo 04-06hr    10 embryo 06-08hr    20 embryo 08-10hr    20 embryo 10-12hr    27 embryo 12-14hr    30 embryo 14-16hr    23 embryo 16-18hr    21 embryo 18-20hr    11 embryo 20-22hr    9 embryo 22-24hr    12 larva L1    9 larva L2    15 larva L3 12hr old    9 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    11 white prepupae new    16 white prepupae 12hr    13 white prepupae 24hr    18 pupae 2d postWPP    22 pupae 3d postWPP    14 pupae 4d postWPP    7 adult male 01day    11 adult male 05day    13 adult male 30day    13 adult female 01day    6 adult female 05day    13 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    13 embryo 02-04hr    13 embryo 04-06hr    10 embryo 06-08hr    20 embryo 08-10hr    20 embryo 10-12hr    27 embryo 12-14hr    30 embryo 14-16hr    23 embryo 16-18hr    21 embryo 18-20hr    11 embryo 20-22hr    9 embryo 22-24hr    12 larva L1    9 larva L2    15 larva L3 12hr old    9 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    11 white prepupae new    16 white prepupae 12hr    13 white prepupae 24hr    18 pupae 2d postWPP    22 pupae 3d postWPP    14 pupae 4d postWPP    7 adult male 01day    11 adult male 05day    13 adult male 30day    13 adult female 01day    6 adult female 05day    13 adult female 30day    12 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    13 embryo 02-04hr    13 embryo 04-06hr    10 embryo 06-08hr    20 embryo 08-10hr    20 embryo 10-12hr    27 embryo 12-14hr    30 embryo 14-16hr    23 embryo 16-18hr    21 embryo 18-20hr    11 embryo 20-22hr    9 embryo 22-24hr    12 larva L1    9 larva L2    15 larva L3 12hr old    9 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    11 white prepupae new    16 white prepupae 12hr    13 white prepupae 24hr    18 pupae 2d postWPP    22 pupae 3d postWPP    14 pupae 4d postWPP    7 adult male 01day    11 adult male 05day    13 adult male 30day    13 adult female 01day    6 adult female 05day    13 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr    13 embryo 02-04hr    13 embryo 04-06hr    10 embryo 06-08hr    20 embryo 08-10hr    20 embryo 10-12hr  27 embryo 12-14hr  30 embryo 14-16hr    23 embryo 16-18hr    21 embryo 18-20hr    11 embryo 20-22hr    9 embryo 22-24hr    12 larva L1    9 larva L2    15 larva L3 12hr old    9 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    11 white prepupae new    16 white prepupae 12hr    13 white prepupae 24hr    18 pupae 2d postWPP    22 pupae 3d postWPP    14 pupae 4d postWPP    7 adult male 01day    11 adult male 05day    13 adult male 30day    13 adult female 01day    6 adult female 05day    13 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    13 embryo 02-04hr    13 embryo 04-06hr    10 embryo 06-08hr    20 embryo 08-10hr    20 embryo 10-12hr    27 embryo 12-14hr    30 embryo 14-16hr    23 embryo 16-18hr    21 embryo 18-20hr    11 embryo 20-22hr    9 embryo 22-24hr    12 larva L1    9 larva L2    15 larva L3 12hr old    9 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    11 white prepupae new    16 white prepupae 12hr    13 white prepupae 24hr    18 pupae 2d postWPP    22 pupae 3d postWPP    14 pupae 4d postWPP    7 adult male 01day    11 adult male 05day    13 adult male 30day    13 adult female 01day    6 adult female 05day    13 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    13 embryo 02-04hr    13 embryo 04-06hr    10 embryo 06-08hr    20 embryo 08-10hr    20 embryo 10-12hr    27 embryo 12-14hr    30 embryo 14-16hr    23 embryo 16-18hr    21 embryo 18-20hr    11 embryo 20-22hr    9 embryo 22-24hr    12 larva L1    9 larva L2    15 larva L3 12hr old    9 larva L3 puffstage 1-2    7 larva L3 puffstage 3-6    9 larva L3 puffstage 7-9    11 white prepupae new    16 white prepupae 12hr    13 white prepupae 24hr    18 pupae 2d postWPP    22 pupae 3d postWPP    14 pupae 4d postWPP    7 adult male 01day    11 adult male 05day    13 adult male 30day    13 adult female 01day    6 adult female 05day    13 adult female 30day    12 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    7 embryonic 1182-4H    5 embryonic GM2    4 embryonic Kc167    4 embryonic S1    3 embryonic S3    4 leg disc CME L1    4 wing disc CME-W2    8 wing disc ML-DmD8    5 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    3 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    6 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    5 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    12 ovary fGS/OSS    2 ovary OSC    2 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    7 embryonic 1182-4H    5 embryonic GM2    4 embryonic Kc167    4 embryonic S1    3 embryonic S3    4 leg disc CME L1    4 wing disc CME-W2    8 wing disc ML-DmD8    5 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    3 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    6 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    5 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    12 ovary fGS/OSS    2 ovary OSC    2 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    7 embryonic 1182-4H    5 embryonic GM2    4 embryonic Kc167    4 embryonic S1    3 embryonic S3    4 leg disc CME L1    4 wing disc CME-W2    8 wing disc ML-DmD8    5 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    3 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    6 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    5 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    12 ovary fGS/OSS    2 ovary OSC    2 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    7 embryonic 1182-4H    5 embryonic GM2    4 embryonic Kc167    4 embryonic S1    3 embryonic S3    4 leg disc CME L1    4 wing disc CME-W2    8 wing disc ML-DmD8    5 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    3 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    6 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    5 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    12 ovary fGS/OSS    2 ovary OSC    2 ovary OSS    0 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    7 embryonic 1182-4H    5 embryonic GM2    4 embryonic Kc167    4 embryonic S1    3 embryonic S3    4 leg disc CME L1    4 wing disc CME-W2    8 wing disc ML-DmD8    5 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    3 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    6 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    5 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    12 ovary fGS/OSS    2 ovary OSC    2 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    7 embryonic 1182-4H    5 embryonic GM2    4 embryonic Kc167    4 embryonic S1    3 embryonic S3    4 leg disc CME L1    4 wing disc CME-W2    8 wing disc ML-DmD8    5 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    3 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    6 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    5 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    12 ovary fGS/OSS    2 ovary OSC    2 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    7 embryonic 1182-4H    5 embryonic GM2    4 embryonic Kc167    4 embryonic S1    3 embryonic S3    4 leg disc CME L1    4 wing disc CME-W2    8 wing disc ML-DmD8    5 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    3 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    6 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    5 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    12 ovary fGS/OSS    2 ovary OSC    2 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    8 Schneider line 2 Sg4    7 embryonic 1182-4H    5 embryonic GM2    4 embryonic Kc167    4 embryonic S1    3 embryonic S3    4 leg disc CME L1    4 wing disc CME-W2    8 wing disc ML-DmD8    5 wing disc ML-DmD9    3 wing disc ML-DmD16-c3    4 wing disc ML-DmD21    3 wing disc ML-DmD32    3 haltere disc ML-DmD17-c3    2 eye-antennal disc ML-DmD11    6 antennal disc ML-DmD20-c5    4 mixed discs ML-DmD4-c1    9 CNS ML-DmBG1-c1    5 CNS ML-DmBG2-c2    7 tumorous blood cells mbn2    12 ovary fGS/OSS    2 ovary OSC    2 ovary OSS    0 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    1 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    3 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    3 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    4 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    1 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    3 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    3 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    4 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    1 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    3 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    3 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    4 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    1 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    3 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    3 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    4 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    1 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    3 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    3 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    4 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    1 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    3 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    3 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    4 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    1 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    3 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    3 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    4 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    0 cold shock, 4-day adult    1 heat shock, 4-day adult    4 Cadmium 50 mM 6 hrs, larvae L3    3 Cadmium 50 mM 12 hrs, larvae L3    4 Cadmium 50 mM 48 hrs, 4-day adult    2 Cadmium 100 mM 48 hrs, 4-day adult    3 Copper 0.5 mM 12 hrs, larvae L3    2 Copper 15 mM 48 hrs, 4-day adult    1 Zinc 5 mM 12 hrs, larvae L3    2 Zinc 4.5 mM 48 hrs, 4-day adult    5 Ethanol 2.5% 3 hrs, larvae L3    3 Ethanol 5% 3 hrs, larvae L3    3 Ethanol 10% 3 hrs, larvae L3    3 Caffeine 1.5 mg/ml 4 hrs, larvae L3    0 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    4 Caffeine 25 mg/ml 48 hrs, 4-day adult    1 Paraquat 5 mM 48 hrs, 4-day adult    4 Paraquat 10 mM 48 hrs, 4-day adult    4 Rotenone 2 μg 12 hrs, larvae L3    4 Rotenone 8 μg 12 hrs, larvae L3    2 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_31 mE1_20_mRNA_expression_cluster_04
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030351 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1840-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG1840 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG1840 Class Mutagen Stocks Known lesion CG1840KK111922 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG1840GD13317 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(1)Exel6243 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD13317} NA P{KK111922} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG1840 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0030351
Orthologs
OrthoDB Orthologs (16) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6PG6MR Dipteran inclusive ortholog search No orthologs identified Insect inclusive ortholog search No orthologs identified Arthropod inclusive ortholog search No orthologs identified Metazoa inclusive ortholog search No orthologs identified
Orthologs in Drosophila Species (EOG6PG6MR)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\CG1840     Drosophila melanogaster fruit fly  Dmel\SelG     Drosophila simulans   Dsim\GD17056 Y Y Drosophila simulans   Dsim\GD17055   Y Drosophila sechellia   Dsec\GM19653 Y Y Drosophila erecta   Dere\GG18451   Y Drosophila erecta   Dere\GG18452 Y Y Drosophila yakuba   Dyak\GE15674 Y Y Drosophila yakuba   Dyak\GE15673   Y Drosophila ananassae   Dana\GF21575   Y Drosophila ananassae   Dana\GF21576 Y Y Drosophila pseudoobscura pseudoobscura   Dpse\GA26643   Y Drosophila persimilis   Dper\GL20156   Y Drosophila willistoni   Dwil\GK25420   Y Drosophila virilis   Dvir\GJ18532   Y Drosophila mojavensis   Dmoj\GI10973   Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects (None identified)
No non-Dipteran orthologies identified
Orthologs in non-Insect Arthropods (None identified)
No non-Insect Arthropod orthologies identified
Orthologs in non-Arthropod Metazoa (None identified)
No non-Arthropod Metazoa orthologies identified
Human Orthologs (0)
Gene OMIM HGNC
AAA Orthologs (5) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD17056 Drosophila sechellia Dsec\GM19653 Drosophila erecta Dere\GG18452 Drosophila yakuba Dyak\GE15674 Drosophila ananassae Dana\GF21576
Stocks & Reagents
Stocks Listed in FlyBase ( 1 )
VDRC	v108492 P{KK111922}VIE-260B
Genomic Clones ( 2 )
	BACR12H01 BACR46E23 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 7 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD12750
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH26466 RE23814
Other clones	16118 35027 81092 EK214228
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030351 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32150
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG1840 BcDNA:LD12750 (FlyBase, 1996-)
Additional comments	Source for merge of CG1840 BcDNA:LD12750 was a shared cDNA (date:020730). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132536 NM_001272545 RefSeq (Proteins) • NP_572764 NP_001259474 DDBJ / EMBL / GenBank • AA440936 AAF48112 AAM11136 AGB95317 AW942246 AY094783 Entrez Gene - A searchable database of RefSeq genes. • 32150 UniProtKB/TrEMBL • Q9VYS6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Selenoprotein SelK/SelG (IPR024491)
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0030351 DRSC - Results from RNAi screens. • FBgn0030351 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030351 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1840-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030351 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32150 modMine - Data generated by the modENCODE project. • FBgn0030351
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	AAF48112 (Martin-Romero et al., 2001) BcDNA:LD12750   CG1840 (Keleman et al., 2009.8.5, Chen et al., 2010)
Name Synonym
Secondary FlyBase IDs
	FBgn0062464
References ( 10 )
Research paper	Castellano et al., 2001, EMBO Rep. 2(8): 697--702 In silico identification of novel selenoproteins in the Drosophila melanogaster genome. [FBrf0137230] Martin-Romero et al., 2001, J. Biol. Chem. 276(32): 29798--29804 Selenium metabolism in Drosophila: selenoproteins, selenoprotein mRNA expression, fertility, and mortality. [FBrf0137271]
Supplementary material	Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Chen et al., 2010, Science 330(6011): Supporting Online Material. [FBrf0216693] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Dietzl et al., 2007, Nature 448(7150): Supplementary Table 1. [FBrf0202579]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946]