• Home
• Tools
  • Tools Overview
  • Query Tools

    
    • QuickSearch
    • QueryBuilder
    • TermLink
    • CytoSearch
    • Interactions Browser
    • ImageBrowse
    • Find A Person
    • Google™ FlyBase
  • Genomic/Map Tools

    
    • BLAST
    • GBrowse
    • CytoSearch
    • Aberrations Maps
    • Chromosome Maps
    • Coordinates Converter
  • Retrieve/Convert

    
    • Batch Download
    • Coordinates Converter
    • ID Converter
  • Data Submission

    
    • Fast-Track Your Paper
    • Submit Personal Comm
    • Add A New Person
    • Update Person Info
  • People

    
    • Find A Person
    • Add A New Person
    • Update Person Info
• Files
  • Files Overview
  • Downloads:
  • Precomputed files
  • Archived data
  • Releases (FTP)
  • Genomes (FTP)
  • AAA data (FTP)
  • Lists:
  • Transposons (Dmel)
  • Transposons (other)
  • Vectors & Constructs
  • Anatomical Terms
  • Map Conversion
• Species
  • Phylogeny
  • Sequenced Species
  • Synteny Table
  • Color Illustrations
  • Abbreviations
• Documents
  • About FlyBase
  • Reference Manual:
  • Sections
  • Contents
  • Nomenclature
  • Release Notes
• Resources
  • All Resources
  • Model Organisms
  • Stock Collections
  • Other links:
  • BDGP
  • DGRC
  • FlyExpress
  • Interactive Fly
  • modENCODE
  • Textpresso for Fly
• News
  • News
  • FlyBase Forum
  • FlyBase Positions
  • Meetings
  • Courses
  • Fly Board
  • White papers
  • Funding
  • bionet.dros
• Help
  • Google™ FlyBase
  • Site Map
  • FAQs
  • FlyBase Guides
  • Video Tutorials
  • Report help
  • New to Flies
  • Pers. comm.
  • Author guidelines
  • Contact FlyBase
• Archives
  • Prior Release
  • Other Archives
  • Coordinate Converter

Gene Dmel\CG1824

General Information
Symbol	Dmel\CG1824	Species	D. melanogaster
Name		Annotation symbol	CG1824
Feature type	protein_coding_gene	FlyBase ID	FBgn0030403
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	11B2-11B2	Sequence location	X:12,486,588..12,489,668 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG1824 (FBgn0030403). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: ATPase activity, coupled to transmembrane movement of substances; transporter activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: transmembrane transport. 4 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: ABC transporter, conserved site; ABC transporter, integral membrane type 1; ABC transporter, transmembrane domain; ABC transporter, transmembrane domain, type 1; ABC transporter-like; ATPase, AAA+ type, core. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, adult female reproductive system, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1625618_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG1824. Gene sequence location is X:12486588..12489668.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA19796 BKN22937
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 11B2-11B2   Limits computationally determined from genome sequence between P{EP}CG11138EP1313 and P{EP}EP1632&P{EP}EP1449
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG1824 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.42
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG1824-RA FBtr0073658  NM_132582   2520   761
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG1824-PA   FBpp0073491   83.6   761   7.91     NP_572810   AAF48177
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • ABC transporter, transmembrane domain (IPR001140) ABC transporter-like (IPR003439) ATPase, AAA+ type, core (IPR003593) ABC transporter, transmembrane domain, type 1 (IPR011527) ABC transporter, conserved site (IPR017871) ABC transporter, integral membrane type 1 (IPR017940) MitoDrome - A database of annotated Dmel nuclear genes encoding mitochondrial proteins • MTDROME01824
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA439255   AE014298 AAF48177   AI388732   AY118801 AAM50661   BI238704   BI367224   BI483075   BI612889   BI620790   CO189745   CO277028   CO282371   CO318716   EC062640   EC089767   EC206864   EC233993
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VYL5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0030403    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0030403 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed within 18-24 hour embryonic stages, during early larval stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0030403 expression level Developmental Stage   Expression Level embryo 00-02hr    2676 embryo 02-04hr    1452 embryo 04-06hr    2024 embryo 06-08hr    2614 embryo 08-10hr    2399 embryo 10-12hr    3702 embryo 12-14hr    1714 embryo 14-16hr    3163 embryo 16-18hr    2840 embryo 18-20hr    3417 embryo 20-22hr    5489 embryo 22-24hr    4245 larva L1    4416 larva L2    3305 larva L3 12hr old    2640 larva L3 puffstage 1-2    1060 larva L3 puffstage 3-6    860 larva L3 puffstage 7-9    738 white prepupae new    776 white prepupae 12hr    826 white prepupae 24hr    891 pupae 2d postWPP    1002 pupae 3d postWPP    1346 pupae 4d postWPP    2435 adult male 01day    2232 adult male 05day    2152 adult male 30day    1929 adult female 01day    3282 adult female 05day    2148 adult female 30day    2326 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2676) embryo 02-04hr  (1452) embryo 04-06hr  (2024) embryo 06-08hr  (2614) embryo 08-10hr  (2399) embryo 10-12hr  (3702) embryo 12-14hr  (1714) embryo 14-16hr  (3163) embryo 16-18hr  (2840) embryo 18-20hr  (3417) embryo 20-22hr  (5489) embryo 22-24hr  (4245) larva L1  (4416) larva L2  (3305) larva L3 12hr old  (2640) larva L3 puffstage 1-2  (1060) larva L3 puffstage 3-6  (860) larva L3 puffstage 7-9  (738) white prepupae new  (776) white prepupae 12hr  (826) white prepupae 24hr  (891) pupae 2d postWPP  (1002) pupae 3d postWPP  (1346) pupae 4d postWPP  (2435) adult male 01day  (2232) adult male 05day  (2152) adult male 30day  (1929) adult female 01day  (3282) adult female 05day  (2148) adult female 30day  (2326) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2676) embryo 02-04hr  1452 embryo 04-06hr  (2024) embryo 06-08hr  (2614) embryo 08-10hr  (2399) embryo 10-12hr  (3702) embryo 12-14hr  (1714) embryo 14-16hr  (3163) embryo 16-18hr  (2840) embryo 18-20hr  (3417) embryo 20-22hr  (5489) embryo 22-24hr  (4245) larva L1  (4416) larva L2  (3305) larva L3 12hr old  (2640) larva L3 puffstage 1-2    1060 larva L3 puffstage 3-6    860 larva L3 puffstage 7-9    738 white prepupae new    776 white prepupae 12hr    826 white prepupae 24hr    891 pupae 2d postWPP    1002 pupae 3d postWPP    1346 pupae 4d postWPP  (2435) adult male 01day  (2232) adult male 05day  (2152) adult male 30day  (1929) adult female 01day  (3282) adult female 05day  (2148) adult female 30day  (2326) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2676 embryo 02-04hr    1452 embryo 04-06hr    2024 embryo 06-08hr    2614 embryo 08-10hr    2399 embryo 10-12hr    3702 embryo 12-14hr    1714 embryo 14-16hr    3163 embryo 16-18hr    2840 embryo 18-20hr    3417 embryo 20-22hr    5489 embryo 22-24hr    4245 larva L1    4416 larva L2    3305 larva L3 12hr old    2640 larva L3 puffstage 1-2    1060 larva L3 puffstage 3-6    860 larva L3 puffstage 7-9    738 white prepupae new    776 white prepupae 12hr    826 white prepupae 24hr    891 pupae 2d postWPP    1002 pupae 3d postWPP    1346 pupae 4d postWPP    2435 adult male 01day    2232 adult male 05day    2152 adult male 30day    1929 adult female 01day    3282 adult female 05day    2148 adult female 30day    2326 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2676 embryo 02-04hr    1452 embryo 04-06hr    2024 embryo 06-08hr    2614 embryo 08-10hr    2399 embryo 10-12hr    3702 embryo 12-14hr    1714 embryo 14-16hr    3163 embryo 16-18hr    2840 embryo 18-20hr    3417 embryo 20-22hr    5489 embryo 22-24hr    4245 larva L1    4416 larva L2    3305 larva L3 12hr old    2640 larva L3 puffstage 1-2    1060 larva L3 puffstage 3-6    860 larva L3 puffstage 7-9    738 white prepupae new    776 white prepupae 12hr    826 white prepupae 24hr    891 pupae 2d postWPP    1002 pupae 3d postWPP    1346 pupae 4d postWPP    2435 adult male 01day    2232 adult male 05day    2152 adult male 30day    1929 adult female 01day    3282 adult female 05day    2148 adult female 30day    2326 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0030403 expression level Developmental Stage   Expression Level embryo 00-02hr    2676 embryo 02-04hr    1452 embryo 04-06hr    2024 embryo 06-08hr    2614 embryo 08-10hr    2399 embryo 10-12hr    3702 embryo 12-14hr    1714 embryo 14-16hr    3163 embryo 16-18hr    2840 embryo 18-20hr    3417 embryo 20-22hr    5489 embryo 22-24hr    4245 larva L1    4416 larva L2    3305 larva L3 12hr old    2640 larva L3 puffstage 1-2    1060 larva L3 puffstage 3-6    860 larva L3 puffstage 7-9    738 white prepupae new    776 white prepupae 12hr    826 white prepupae 24hr    891 pupae 2d postWPP    1002 pupae 3d postWPP    1346 pupae 4d postWPP    2435 adult male 01day    2232 adult male 05day    2152 adult male 30day    1929 adult female 01day    3282 adult female 05day    2148 adult female 30day    2326 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (2676) embryo 02-04hr  (1452) embryo 04-06hr  (2024) embryo 06-08hr  (2614) embryo 08-10hr  (2399) embryo 10-12hr  (3702) embryo 12-14hr  (1714) embryo 14-16hr  (3163) embryo 16-18hr  (2840) embryo 18-20hr  (3417) embryo 20-22hr  (5489) embryo 22-24hr  (4245) larva L1  (4416) larva L2  (3305) larva L3 12hr old  (2640) larva L3 puffstage 1-2  (1060) larva L3 puffstage 3-6  (860) larva L3 puffstage 7-9  (738) white prepupae new  (776) white prepupae 12hr  (826) white prepupae 24hr  (891) pupae 2d postWPP  (1002) pupae 3d postWPP  (1346) pupae 4d postWPP  (2435) adult male 01day  (2232) adult male 05day  (2152) adult male 30day  (1929) adult female 01day  (3282) adult female 05day  (2148) adult female 30day  (2326) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (2676) embryo 02-04hr  1452 embryo 04-06hr  2024 embryo 06-08hr  (2614) embryo 08-10hr  2399 embryo 10-12hr  (3702) embryo 12-14hr  1714 embryo 14-16hr  (3163) embryo 16-18hr  (2840) embryo 18-20hr  (3417) embryo 20-22hr  (5489) embryo 22-24hr  (4245) larva L1  (4416) larva L2  (3305) larva L3 12hr old  (2640) larva L3 puffstage 1-2    1060 larva L3 puffstage 3-6    860 larva L3 puffstage 7-9    738 white prepupae new    776 white prepupae 12hr    826 white prepupae 24hr    891 pupae 2d postWPP    1002 pupae 3d postWPP    1346 pupae 4d postWPP  2435 adult male 01day  2232 adult male 05day  2152 adult male 30day  1929 adult female 01day  (3282) adult female 05day  2148 adult female 30day  2326 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    2676 embryo 02-04hr    1452 embryo 04-06hr    2024 embryo 06-08hr    2614 embryo 08-10hr    2399 embryo 10-12hr    3702 embryo 12-14hr    1714 embryo 14-16hr    3163 embryo 16-18hr    2840 embryo 18-20hr    3417 embryo 20-22hr    5489 embryo 22-24hr    4245 larva L1    4416 larva L2    3305 larva L3 12hr old    2640 larva L3 puffstage 1-2    1060 larva L3 puffstage 3-6    860 larva L3 puffstage 7-9    738 white prepupae new    776 white prepupae 12hr    826 white prepupae 24hr    891 pupae 2d postWPP    1002 pupae 3d postWPP    1346 pupae 4d postWPP    2435 adult male 01day    2232 adult male 05day    2152 adult male 30day    1929 adult female 01day    3282 adult female 05day    2148 adult female 30day    2326 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    2676 embryo 02-04hr    1452 embryo 04-06hr    2024 embryo 06-08hr    2614 embryo 08-10hr    2399 embryo 10-12hr    3702 embryo 12-14hr    1714 embryo 14-16hr    3163 embryo 16-18hr    2840 embryo 18-20hr    3417 embryo 20-22hr    5489 embryo 22-24hr    4245 larva L1    4416 larva L2    3305 larva L3 12hr old    2640 larva L3 puffstage 1-2    1060 larva L3 puffstage 3-6    860 larva L3 puffstage 7-9    738 white prepupae new    776 white prepupae 12hr    826 white prepupae 24hr    891 pupae 2d postWPP    1002 pupae 3d postWPP    1346 pupae 4d postWPP    2435 adult male 01day    2232 adult male 05day    2152 adult male 30day    1929 adult female 01day    3282 adult female 05day    2148 adult female 30day    2326 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0030403    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0030403 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult central nervous system, larval/adult midgut, larval/adult hindgut, adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, adult female reproductive system, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0030403 expression level Tissue   Expression Level Larval Central Nervous System    95.475 Larval Midgut    199.7 Larval Hindgut    158.4 Larval Malpighian Tubules    44.6 Larval Fat Body    26.9 Larval Salivary Gland    112 Larval Trachea    67.55 Larval Carcass    64.5 Adult Head    75.4 Adult Eye    87.375 Adult Brain    113.5 Adult Thoracic-Abdominal Ganglion    119.8 Adult Crop    90.7 Adult Midgut    174.8 Adult Hindgut    139.5 Adult Malpighian Tubules    149.7 Adult Fat Body    131.5 Adult Salivary Gland    167.9 Adult Heart    100.125 Adult VirginFemale Spermatheca    113 Adult InseminatedFemale Spermatheca    128.6 Adult Ovary    103.1 Adult Testis    35.5 Adult Male Accessory Gland    70.7 Adult Carcass    111.3 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    95.475 Larval Midgut    199.7 Larval Hindgut    158.4 Larval Malpighian Tubules    44.6 Larval Fat Body    26.9 Larval Salivary Gland    112 Larval Trachea    67.55 Larval Carcass    64.5 Adult Head    75.4 Adult Eye    87.375 Adult Brain    113.5 Adult Thoracic-Abdominal Ganglion    119.8 Adult Crop    90.7 Adult Midgut    174.8 Adult Hindgut    139.5 Adult Malpighian Tubules    149.7 Adult Fat Body    131.5 Adult Salivary Gland    167.9 Adult Heart    100.125 Adult VirginFemale Spermatheca    113 Adult InseminatedFemale Spermatheca    128.6 Adult Ovary    103.1 Adult Testis    35.5 Adult Male Accessory Gland    70.7 Adult Carcass    111.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    95.475 Larval Midgut    199.7 Larval Hindgut    158.4 Larval Malpighian Tubules    44.6 Larval Fat Body    26.9 Larval Salivary Gland    112 Larval Trachea    67.55 Larval Carcass    64.5 Adult Head    75.4 Adult Eye    87.375 Adult Brain    113.5 Adult Thoracic-Abdominal Ganglion    119.8 Adult Crop    90.7 Adult Midgut    174.8 Adult Hindgut    139.5 Adult Malpighian Tubules    149.7 Adult Fat Body    131.5 Adult Salivary Gland    167.9 Adult Heart    100.125 Adult VirginFemale Spermatheca    113 Adult InseminatedFemale Spermatheca    128.6 Adult Ovary    103.1 Adult Testis    35.5 Adult Male Accessory Gland    70.7 Adult Carcass    111.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    95.475 Larval Midgut    199.7 Larval Hindgut    158.4 Larval Malpighian Tubules    44.6 Larval Fat Body    26.9 Larval Salivary Gland    112 Larval Trachea    67.55 Larval Carcass    64.5 Adult Head    75.4 Adult Eye    87.375 Adult Brain    113.5 Adult Thoracic-Abdominal Ganglion    119.8 Adult Crop    90.7 Adult Midgut    174.8 Adult Hindgut    139.5 Adult Malpighian Tubules    149.7 Adult Fat Body    131.5 Adult Salivary Gland    167.9 Adult Heart    100.125 Adult VirginFemale Spermatheca    113 Adult InseminatedFemale Spermatheca    128.6 Adult Ovary    103.1 Adult Testis    35.5 Adult Male Accessory Gland    70.7 Adult Carcass    111.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0030403 expression level Tissue   Expression Level Larval Central Nervous System    95.475 Larval Midgut    199.7 Larval Hindgut    158.4 Larval Malpighian Tubules    44.6 Larval Fat Body    26.9 Larval Salivary Gland    112 Larval Trachea    67.55 Larval Carcass    64.5 Adult Head    75.4 Adult Eye    87.375 Adult Brain    113.5 Adult Thoracic-Abdominal Ganglion    119.8 Adult Crop    90.7 Adult Midgut    174.8 Adult Hindgut    139.5 Adult Malpighian Tubules    149.7 Adult Fat Body    131.5 Adult Salivary Gland    167.9 Adult Heart    100.125 Adult VirginFemale Spermatheca    113 Adult InseminatedFemale Spermatheca    128.6 Adult Ovary    103.1 Adult Testis    35.5 Adult Male Accessory Gland    70.7 Adult Carcass    111.3 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    95.475 Larval Midgut    199.7 Larval Hindgut    158.4 Larval Malpighian Tubules    44.6 Larval Fat Body    26.9 Larval Salivary Gland    112 Larval Trachea    67.55 Larval Carcass    64.5 Adult Head    75.4 Adult Eye    87.375 Adult Brain    113.5 Adult Thoracic-Abdominal Ganglion    119.8 Adult Crop    90.7 Adult Midgut    174.8 Adult Hindgut    139.5 Adult Malpighian Tubules    149.7 Adult Fat Body    131.5 Adult Salivary Gland    167.9 Adult Heart    100.125 Adult VirginFemale Spermatheca    113 Adult InseminatedFemale Spermatheca    128.6 Adult Ovary    103.1 Adult Testis    35.5 Adult Male Accessory Gland    70.7 Adult Carcass    111.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    95.475 Larval Midgut    199.7 Larval Hindgut    158.4 Larval Malpighian Tubules    44.6 Larval Fat Body    26.9 Larval Salivary Gland    112 Larval Trachea    67.55 Larval Carcass    64.5 Adult Head    75.4 Adult Eye    87.375 Adult Brain    113.5 Adult Thoracic-Abdominal Ganglion    119.8 Adult Crop    90.7 Adult Midgut    174.8 Adult Hindgut    139.5 Adult Malpighian Tubules    149.7 Adult Fat Body    131.5 Adult Salivary Gland    167.9 Adult Heart    100.125 Adult VirginFemale Spermatheca    113 Adult InseminatedFemale Spermatheca    128.6 Adult Ovary    103.1 Adult Testis    35.5 Adult Male Accessory Gland    70.7 Adult Carcass    111.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    95.475 Larval Midgut    199.7 Larval Hindgut    158.4 Larval Malpighian Tubules    44.6 Larval Fat Body    26.9 Larval Salivary Gland    112 Larval Trachea    67.55 Larval Carcass    64.5 Adult Head    75.4 Adult Eye    87.375 Adult Brain    113.5 Adult Thoracic-Abdominal Ganglion    119.8 Adult Crop    90.7 Adult Midgut    174.8 Adult Hindgut    139.5 Adult Malpighian Tubules    149.7 Adult Fat Body    131.5 Adult Salivary Gland    167.9 Adult Heart    100.125 Adult VirginFemale Spermatheca    113 Adult InseminatedFemale Spermatheca    128.6 Adult Ovary    103.1 Adult Testis    35.5 Adult Male Accessory Gland    70.7 Adult Carcass    111.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    75.4   NA  Eye    87.375   NA  Brain    113.5   95.475  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    119.8   NA  Crop    90.7   199.7  Midgut    174.8   158.4  Hindgut    139.5   44.6  Malpighian Tubules    149.7   26.9  Fat Body    131.5   112  Salivary Gland    167.9   NA  Heart    100.125   67.55  Trachea    NA   NA  VirginFemale Spermatheca    113   NA  InseminatedFemale Spermatheca    128.6   NA  Ovary    103.1   NA  Testis    35.5   NA  Male Accessory Gland    70.7   64.5  Carcass    111.3 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_19
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030403 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1824-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG1824GD3333 Phenotype manifest in Allele
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of CG1824 Class Mutagen Stocks Known lesion CG18245-SZ-4090 1 -- CG1824GG01740 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG1824 Class Mutagen Stocks Known lesion CG1824GD3333 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG1824KK102841 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD3333} NA P{KK102841} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions P{RS5}CG18245-SZ-4090 NA insertion of mobile activating element P{Mae-UAS.6.11}CG1824GG01740 NA
Gene Ontology: Function, Process & Cellular Component ( 6 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 6 terms )
Molecular Function
CV term Evidence References
ATPase activity, coupled to transmembrane movement of substances inferred from sequence or structural similarity with UniProtKB:Q9NUT2 (FlyBase, 1992-, Sardiello et al., 2003.6.11) ATP binding inferred from electronic annotation with InterPro:IPR001140, InterPro:IPR003439, InterPro:IPR011527, InterPro:IPR017871 (FlyBase Curators et al., 2004-) transporter activity inferred from sequence or structural similarity with UniProtKB:Q9NUT2 (FlyBase, 1992-, Sardiello et al., 2003.6.11)
Biological Process
CV term Evidence References
transmembrane transport inferred from electronic annotation with InterPro:IPR001140, InterPro:IPR011527 (FlyBase Curators et al., 2004-)
Cellular Component
CV term Evidence References
integral to membrane inferred from electronic annotation with InterPro:IPR001140, InterPro:IPR011527 (FlyBase Curators et al., 2004-) mitochondrial inner membrane inferred from sequence or structural similarity with UniProtKB:Q9NUT2 (Sardiello et al., 2003.6.11)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG1824 allele Gene References
External Data
Linkouts	DroID - A comprehensive database of gene and protein interactions. • FBgn0030403 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32208
Orthologs
Genome-wide drosophilid orthologs	Dana\GF20900 Dere\GG19546 Dgri\GH24830 Dmoj\GI16162 Dper\GL25340 Dpse\GA14849 Dsec\GM11542 Dsim\GD15923 Dvir\GJ16655 Dwil\GK25432 Dyak\GE16208
Curated drosophilid orthologs	Dpse\GA14849
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL002468-PA Aedes aegypti (mosquito) AGAP006273-PA Anopheles gambiae (mosquito) XP_624810.2 Apis mellifera (honey bee) XP_001942699.1 Acyrthosiphon pisum (pea aphid) 235264 Branchiostoma floridae (lancelet) XP_001894558.1 Brugia malayi (roundworm nematode) BGIBMGA004142-PA Bombyx mori (silk worm) CN13899 Caenorhabditis brenneri (small nematode) CBP25875 Caenorhabditis briggsae (nematode) CE39850 Caenorhabditis elegans (worm) ENSCAFP00000035148 Canis familiaris (dog) ENSCINP00000003293 Ciona intestinalis (sea squirt) JA17344 Caenorhabditis japonica (nematode) CPIJ010656 Culex pipens (mosquito) ENSCPOP00000003963 Cavia porcellus (guinea pig) RP45188 Caenorhabditis remanei (nematode) ENSCSAVP00000002233 Ciona savignyi (sedentary tunicate) 155008 Capitella spl (polychaete worm) DDB0208540 Dictyostelium discoideum (amoeba) 318037 Daphnia pulex (daphnia) ENSDARP00000073658 Danio rerio (zebra fish) ENSECAP00000008101 Equus caballus (horse) XP_649976 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000023755 Gymnopilus aculeatus (mushroom) 94228 Hypsipyla robusta (cedar shoot borer) ENSP00000297504 Homo sapiens (human) ISCW005908-PA Ixodes scapularis (deer tick) 208936 Lottia gigantea (owl limpet) 29884 Monocosta brevicollis (choanoflagellate) ENSMODP00000004828 Monodelphis domestica (gray opossum) ENSMMUP00000026921 Macaca mulatta (rhesus monkey) ENSMUSP00000110729 Mus musculus (house mouse) 206043 Nematostella vectensis (starlet anemone) ENSORLP00000021952 Oryzias latipes (japanese killifish) PHUM004324-PA Pediculus humanus (human body louse) PP27032 Pristionchus pacificus (nematode) ENSPPYP00000020387 Pongo pygmaeus (orangutan) ENSPTRP00000034025 Pan troglodytes (chimpanzee) ENSRNOP00000012222 Rattus norvegicus (norway rat) Smp_063000 Schistosoma mansoni (trematode parasite) 19732 Trichoplax adhaerens (metazoa) XP_972133.1 Tribolium castaneum (red flour beetle) ENSTNIP00000011331 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000007520 Takifugu rubripes (pufferfish Takifugu) 84370.m00097 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000002928 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17883 LH23254 ISCW005908 FBgn0233749 FBgn0227391 FBgn0203839 FBgn0187572 FBgn0166485 JGI_V11_318037 FBgn0074876 FBgn0162924 FBgn0138911 FBgn0132285 FBgn0111748 FBgn0097906 CPIJ010656 BGIBMGA004142 ACYPI009686 GB12032 AGAP006273 AAEL002468 PHUM200130 GLEAN_09730
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	19929 y1 w67c23 P{Mae-UAS.6.11}CG1824GG01740
Kyoto	126336 w1118 P{RS5}CG18245-SZ-4090
VDRC	v106935 P{KK102841}VIE-260B v5554 w1118; P{GD3333}v5554
Genomic Clones ( 2 )
	BACR39P03 BACR48G08 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 15 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GH19726
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LD13767 RE35223 RE52938 RE65915 RH41878 RH52009
Other clones	43859 56530 172992 CK01.55B.C10 EK045043 EK122703 EK160323 EK273515
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030403 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32208
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132582 RefSeq (Proteins) • NP_572810 DDBJ / EMBL / GenBank • AAF48177 AAM50661 AI388732 AY118801 Entrez Gene - A searchable database of RefSeq genes. • 32208 UniProtKB/TrEMBL • Q9VYL5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • ABC transporter, transmembrane domain (IPR001140) ABC transporter-like (IPR003439) ATPase, AAA+ type, core (IPR003593) ABC transporter, transmembrane domain, type 1 (IPR011527) ABC transporter, conserved site (IPR017871) ABC transporter, integral membrane type 1 (IPR017940) MitoDrome - A database of annotated Dmel nuclear genes encoding mitochondrial proteins • MTDROME01824
Linkouts
	DroID - A comprehensive database of gene and protein interactions. • FBgn0030403 DRSC - Results from RNAi screens. • FBgn0030403 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030403 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG1824-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030403 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32208 InParanoid A subset of ortholog calls from InParanoid. • AAEL002468-PA Aedes aegypti (mosquito) AGAP006273-PA Anopheles gambiae (mosquito) XP_624810.2 Apis mellifera (honey bee) XP_001942699.1 Acyrthosiphon pisum (pea aphid) 235264 Branchiostoma floridae (lancelet) XP_001894558.1 Brugia malayi (roundworm nematode) BGIBMGA004142-PA Bombyx mori (silk worm) CN13899 Caenorhabditis brenneri (small nematode) CBP25875 Caenorhabditis briggsae (nematode) CE39850 Caenorhabditis elegans (worm) ENSCAFP00000035148 Canis familiaris (dog) ENSCINP00000003293 Ciona intestinalis (sea squirt) JA17344 Caenorhabditis japonica (nematode) CPIJ010656 Culex pipens (mosquito) ENSCPOP00000003963 Cavia porcellus (guinea pig) RP45188 Caenorhabditis remanei (nematode) ENSCSAVP00000002233 Ciona savignyi (sedentary tunicate) 155008 Capitella spl (polychaete worm) DDB0208540 Dictyostelium discoideum (amoeba) 318037 Daphnia pulex (daphnia) ENSDARP00000073658 Danio rerio (zebra fish) ENSECAP00000008101 Equus caballus (horse) XP_649976 Entamoeba histolytica (anaerobic protozoan) ENSGACP00000023755 Gymnopilus aculeatus (mushroom) 94228 Hypsipyla robusta (cedar shoot borer) ENSP00000297504 Homo sapiens (human) ISCW005908-PA Ixodes scapularis (deer tick) 208936 Lottia gigantea (owl limpet) 29884 Monocosta brevicollis (choanoflagellate) ENSMODP00000004828 Monodelphis domestica (gray opossum) ENSMMUP00000026921 Macaca mulatta (rhesus monkey) ENSMUSP00000110729 Mus musculus (house mouse) 206043 Nematostella vectensis (starlet anemone) ENSORLP00000021952 Oryzias latipes (japanese killifish) PHUM004324-PA Pediculus humanus (human body louse) PP27032 Pristionchus pacificus (nematode) ENSPPYP00000020387 Pongo pygmaeus (orangutan) ENSPTRP00000034025 Pan troglodytes (chimpanzee) ENSRNOP00000012222 Rattus norvegicus (norway rat) Smp_063000 Schistosoma mansoni (trematode parasite) 19732 Trichoplax adhaerens (metazoa) XP_972133.1 Tribolium castaneum (red flour beetle) ENSTNIP00000011331 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000007520 Takifugu rubripes (pufferfish Takifugu) 84370.m00097 Trichomonas vaginalis (parasitic flagellated protozoan) ENSXETP00000002928 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32208 modMine - Data generated by the modENCODE project. • FBgn0030403 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17883 LH23254 ISCW005908 FBgn0233749 FBgn0227391 FBgn0203839 FBgn0187572 FBgn0166485 JGI_V11_318037 FBgn0074876 FBgn0162924 FBgn0138911 FBgn0132285 FBgn0111748 FBgn0097906 CPIJ010656 BGIBMGA004142 ACYPI009686 GB12032 AGAP006273 AAEL002468 PHUM200130 GLEAN_09730
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG1824 (Legube et al., 2006, Ricardo and Lehmann, 2009, Mayer et al., 2009, Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 18 )
Research paper	Blanco et al., 2010, BMC Dev. Biol. 10: 94 Gene expression following induction of regeneration in Drosophila wing imaginal discs. Expression profile of regenerating wing discs. [FBrf0211812] Mayer et al., 2009, J. Neurosci. 29(11): 3538--3550 Evolutionary conservation of vertebrate blood-brain barrier chemoprotective mechanisms in Drosophila. [FBrf0207483] Legube et al., 2006, Genes Dev. 20(7): 871--883 X-chromosome-wide profiling of MSL-1 distribution and dosage compensation in Drosophila. [FBrf0190549]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Ricardo and Lehmann, 2009, Science 323(5916): An ABC Transporter Controls Export of a Drosophila Germ Cell Attractant. [FBrf0207632]
Review	Dean et al., 2001, Genome Res. 11: 1156--1166 The human ATP-binding cassette (ABC) transporter superfamily. [FBrf0159553]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Sardiello et al., 2003.6.11, MitoDrome: A database of Drosophila melanogaster nuclear genes encoding proteins targeted to the mitochondrion. MitoDrome: A database of Drosophila melanogaster nuclear genes encoding proteins targeted to the mitochondrion. [FBrf0159903]
FlyBase analysis	FlyBase Curators, 2008, Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. Insertion identifiers and alleles based on genomic location of insertions with respect to gene annotations. [FBrf0202955] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Stock list	Bloomington Drosophila Stock Center, 19??-, Bloomington Stock List. Bloomington Stock List. [FBrf0141259]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
Curated genome annotation	Ketchum, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126677]