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Gene Dmel\NFAT

General Information
Symbol	Dmel\NFAT	Species	D. melanogaster
Name	NFAT homolog	Annotation symbol	CG11172
Feature type	protein_coding_gene	FlyBase ID	FBgn0030505
Gene Model Status	Current	Stock availability	23 publicly available
Also Known As	EP1335
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	12A9-12B2	Sequence location	X:13,518,790..13,557,690 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene NFAT homolog is referred to in FlyBase by the symbol Dmel\NFAT (CG11172, FBgn0030505). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: sequence-specific DNA binding transcription factor activity. There is experimental evidence that it is involved in the biological process: negative regulation of synaptic vesicle exocytosis; response to salt stress. 49 alleles are reported. The phenotypes of these alleles are annotated with: organ system subdivision; organ system; adult segment; peripheral nervous system; embryonic/larval neuron; synapse; integumentary plate; thoracic segment; eo support cell; embryonic/larval anal pad; external compound sense organ. It has 5 annotated transcripts and 5 annotated polypeptides. Protein features are: Armadillo-like helical; Cell surface receptor IPT/TIG; Immunoglobulin E-set; Immunoglobulin-like fold; Nuclear factor of activated T cells (NFAT); Rel homology; p53-like transcription factor, DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1632922_at completely aligns to an exonic region of only a subset of 4 of the 5 FlyBase-annotated transcript isoforms of NFAT. Gene sequence location is X:13518790..13557690.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	Clones RE22351
FB2012_01	References Reis et al., 2010, PLoS Genet. 6(11): e1001206 Carreira et al., 2011, BMC Dev. Biol. 11: 32 Sequence features HFA19393 HFA18991 BKN22466
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 12A9-12B2   Limits computationally determined from genome sequence between P{EP}CG1640EP1626 and P{EP}NFATEP1353&P{EP}NFATEP1508
Experimentally Determined Cytological Location
Cytogenetic map Notes References 12A8-12A10     (Huang, 1999.10.18) 12A8-12A10   (determined by in situ hybridisation)   (Huang and Rubin, 2000) 12A8-12A10   (determined by in situ hybridisation)   (Abdelilah-Seyfried et al., 2000)
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\NFAT for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) NFAT-RA FBtr0073808  NM_078592   5858   1419 NFAT-RB FBtr0112980  NM_001103504   5646   1457 NFAT-RC FBtr0301449  NM_001169274   5019   1248 NFAT-RD FBtr0301450  NM_001169275   5231   1210 NFAT-RE FBtr0301451  NM_001169276   2514   600
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein NFAT-PA   FBpp0073639   150.7   1419   6.77     NP_511147   AAF48297 NFAT-PB   FBpp0111893   155.8   1457   6.89     NP_001096974   ABW09408 NFAT-PC   FBpp0290664   133.0   1248   7.12     NP_001162745   ACZ95280 NFAT-PD   FBpp0290665   127.9   1210   6.99     NP_001162746   ACZ95281 NFAT-PE   FBpp0290666   66.2   600   9.91     NP_001162747   ACZ95282
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Cell surface receptor IPT/TIG (IPR002909) Nuclear factor of activated T cells (NFAT) (IPR008366) p53-like transcription factor, DNA-binding (IPR008967) Rel homology (IPR011539) Immunoglobulin-like fold (IPR013783) Immunoglobulin E-set (IPR014756) Armadillo-like helical (IPR011989)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA391997   AA801630   AA816813   AA941009   AA950353   AA951593   AA979220   AE014298 AAF48297   AE014298 ABW09408   AE014298 ACZ95280   AE014298 ACZ95281   AE014298 ACZ95282   AF195496 AAG28468   AI108246   AI109382   AQ025361   AQ025413   AQ025433   AQ073194   AQ073198   AQ073228   AQ073251   AW942165   BG638026   BG638661   BH740834   BH740835   BI215752   BT003742 AAO40817   BT015267 AAT94496   BT030307   CL706570   CO179193   CO179430   CO179448   CO181823   CO189434   CO196396   CO261817   CO261861   CO262016   CO262889   CO263099   CO263254   CO263324   CO263452   CO263455   CO265894   CO266269   CO266294   CO271261   CO274952   CO279329   CO282867   CO283080   CO283256   CO283933   CO284392   CO285778   CO290259   CO290262   CO290264   CO291116   CO291128   CO291415   CO293166   CO293532   CO295433   CO296654   CO296690   CO297899   CO297975   CO298438   CO298566   CO298602   CO300246   CO302039   CO304479   CO305297   CO307475   CO307490   CO308827   CO310483   CO310887   CO311949   CO313897   CO321211   CO323264   CO324200   CO324874   CO325763   CO325800   CO330535   CO331987   CO332992   CO340139   CO343376   CO344119   CZ467895   CZ471477   CZ472456   CZ475653   CZ478499   CZ479450   DN154397   EC056783   EC059336   EC060497   EC063486   EC065311   EC066298   EC066679   EC069860   EC070755   EC070776   EC070827   EC071469   EC075742   EC079314   EC082348   EC086138   EC087554   EC196514   EC196739   EC197851   EC199905   EC200739   EC201753   EC205227   EC206795   EC208158   EC208226   EC208285   EC208317   EC210419   EC210845   EC211254   EC211520   EC212548   EC212590   EC213007   EC214062   EC215999   EC216505   EC218150   EC218151   EC218831   EC222824   EC226468   EC228792   EC230869   EC231057   EC231209   EC231257   EC231351   EC233569   EC233940   EC237878   EC238085   EC241195   EC242576   EC242874   EC244599   EC245509   EC246183   EC246791   EC250827   EC251008   EC252793   EC255299   EC258548   GH942716   GH945060   GH947184   GH954766   GH983647   GR705829
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q86NT0 Q9GU53 Q9VYA6 A8JUV3 E1JJP6 E1JJP5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0030505    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0030505 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed at stages throughout embryogenesis, at stages throughout the pupal period. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0030505 expression level Developmental Stage   Expression Level embryo 00-02hr    1607 embryo 02-04hr    1770 embryo 04-06hr    1183 embryo 06-08hr    1441 embryo 08-10hr    1236 embryo 10-12hr    1204 embryo 12-14hr    1414 embryo 14-16hr    1974 embryo 16-18hr    1390 embryo 18-20hr    1453 embryo 20-22hr    2585 embryo 22-24hr    1736 larva L1    1023 larva L2    561 larva L3 12hr old    500 larva L3 puffstage 1-2    304 larva L3 puffstage 3-6    1049 larva L3 puffstage 7-9    982 white prepupae new    957 white prepupae 12hr    2198 white prepupae 24hr    1861 pupae 2d postWPP    1596 pupae 3d postWPP    1176 pupae 4d postWPP    678 adult male 01day    691 adult male 05day    694 adult male 30day    826 adult female 01day    1067 adult female 05day    933 adult female 30day    938 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1607) embryo 02-04hr  (1770) embryo 04-06hr  (1183) embryo 06-08hr  (1441) embryo 08-10hr  (1236) embryo 10-12hr  (1204) embryo 12-14hr  (1414) embryo 14-16hr  (1974) embryo 16-18hr  (1390) embryo 18-20hr  (1453) embryo 20-22hr  (2585) embryo 22-24hr  (1736) larva L1  (1023) larva L2  (561) larva L3 12hr old  (500) larva L3 puffstage 1-2  (304) larva L3 puffstage 3-6  (1049) larva L3 puffstage 7-9  (982) white prepupae new  (957) white prepupae 12hr  (2198) white prepupae 24hr  (1861) pupae 2d postWPP  (1596) pupae 3d postWPP  (1176) pupae 4d postWPP  (678) adult male 01day  (691) adult male 05day  (694) adult male 30day  (826) adult female 01day  (1067) adult female 05day  (933) adult female 30day  (938) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1607) embryo 02-04hr  (1770) embryo 04-06hr    1183 embryo 06-08hr  1441 embryo 08-10hr    1236 embryo 10-12hr    1204 embryo 12-14hr  1414 embryo 14-16hr  (1974) embryo 16-18hr    1390 embryo 18-20hr  1453 embryo 20-22hr  (2585) embryo 22-24hr  (1736) larva L1    1023 larva L2    561 larva L3 12hr old    500 larva L3 puffstage 1-2    304 larva L3 puffstage 3-6    1049 larva L3 puffstage 7-9    982 white prepupae new    957 white prepupae 12hr  (2198) white prepupae 24hr  (1861) pupae 2d postWPP  (1596) pupae 3d postWPP    1176 pupae 4d postWPP    678 adult male 01day    691 adult male 05day    694 adult male 30day    826 adult female 01day    1067 adult female 05day    933 adult female 30day    938 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1607 embryo 02-04hr    1770 embryo 04-06hr    1183 embryo 06-08hr    1441 embryo 08-10hr    1236 embryo 10-12hr    1204 embryo 12-14hr    1414 embryo 14-16hr    1974 embryo 16-18hr    1390 embryo 18-20hr    1453 embryo 20-22hr    2585 embryo 22-24hr    1736 larva L1    1023 larva L2    561 larva L3 12hr old    500 larva L3 puffstage 1-2    304 larva L3 puffstage 3-6    1049 larva L3 puffstage 7-9    982 white prepupae new    957 white prepupae 12hr    2198 white prepupae 24hr    1861 pupae 2d postWPP    1596 pupae 3d postWPP    1176 pupae 4d postWPP    678 adult male 01day    691 adult male 05day    694 adult male 30day    826 adult female 01day    1067 adult female 05day    933 adult female 30day    938 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1607 embryo 02-04hr    1770 embryo 04-06hr    1183 embryo 06-08hr    1441 embryo 08-10hr    1236 embryo 10-12hr    1204 embryo 12-14hr    1414 embryo 14-16hr    1974 embryo 16-18hr    1390 embryo 18-20hr    1453 embryo 20-22hr    2585 embryo 22-24hr    1736 larva L1    1023 larva L2    561 larva L3 12hr old    500 larva L3 puffstage 1-2    304 larva L3 puffstage 3-6    1049 larva L3 puffstage 7-9    982 white prepupae new    957 white prepupae 12hr    2198 white prepupae 24hr    1861 pupae 2d postWPP    1596 pupae 3d postWPP    1176 pupae 4d postWPP    678 adult male 01day    691 adult male 05day    694 adult male 30day    826 adult female 01day    1067 adult female 05day    933 adult female 30day    938 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0030505 expression level Developmental Stage   Expression Level embryo 00-02hr    1607 embryo 02-04hr    1770 embryo 04-06hr    1183 embryo 06-08hr    1441 embryo 08-10hr    1236 embryo 10-12hr    1204 embryo 12-14hr    1414 embryo 14-16hr    1974 embryo 16-18hr    1390 embryo 18-20hr    1453 embryo 20-22hr    2585 embryo 22-24hr    1736 larva L1    1023 larva L2    561 larva L3 12hr old    500 larva L3 puffstage 1-2    304 larva L3 puffstage 3-6    1049 larva L3 puffstage 7-9    982 white prepupae new    957 white prepupae 12hr    2198 white prepupae 24hr    1861 pupae 2d postWPP    1596 pupae 3d postWPP    1176 pupae 4d postWPP    678 adult male 01day    691 adult male 05day    694 adult male 30day    826 adult female 01day    1067 adult female 05day    933 adult female 30day    938 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1607) embryo 02-04hr  (1770) embryo 04-06hr  (1183) embryo 06-08hr  (1441) embryo 08-10hr  (1236) embryo 10-12hr  (1204) embryo 12-14hr  (1414) embryo 14-16hr  (1974) embryo 16-18hr  (1390) embryo 18-20hr  (1453) embryo 20-22hr  (2585) embryo 22-24hr  (1736) larva L1  (1023) larva L2  (561) larva L3 12hr old  (500) larva L3 puffstage 1-2  (304) larva L3 puffstage 3-6  (1049) larva L3 puffstage 7-9  (982) white prepupae new  (957) white prepupae 12hr  (2198) white prepupae 24hr  (1861) pupae 2d postWPP  (1596) pupae 3d postWPP  (1176) pupae 4d postWPP  (678) adult male 01day  (691) adult male 05day  (694) adult male 30day  (826) adult female 01day  (1067) adult female 05day  (933) adult female 30day  (938) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  1607 embryo 02-04hr  1770 embryo 04-06hr    1183 embryo 06-08hr  1441 embryo 08-10hr    1236 embryo 10-12hr    1204 embryo 12-14hr  1414 embryo 14-16hr  1974 embryo 16-18hr    1390 embryo 18-20hr  1453 embryo 20-22hr  (2585) embryo 22-24hr  1736 larva L1    1023 larva L2    561 larva L3 12hr old    500 larva L3 puffstage 1-2    304 larva L3 puffstage 3-6    1049 larva L3 puffstage 7-9    982 white prepupae new    957 white prepupae 12hr  2198 white prepupae 24hr  1861 pupae 2d postWPP  1596 pupae 3d postWPP    1176 pupae 4d postWPP    678 adult male 01day    691 adult male 05day    694 adult male 30day    826 adult female 01day    1067 adult female 05day    933 adult female 30day    938 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1607 embryo 02-04hr    1770 embryo 04-06hr    1183 embryo 06-08hr    1441 embryo 08-10hr    1236 embryo 10-12hr    1204 embryo 12-14hr    1414 embryo 14-16hr    1974 embryo 16-18hr    1390 embryo 18-20hr    1453 embryo 20-22hr    2585 embryo 22-24hr    1736 larva L1    1023 larva L2    561 larva L3 12hr old    500 larva L3 puffstage 1-2    304 larva L3 puffstage 3-6    1049 larva L3 puffstage 7-9    982 white prepupae new    957 white prepupae 12hr    2198 white prepupae 24hr    1861 pupae 2d postWPP    1596 pupae 3d postWPP    1176 pupae 4d postWPP    678 adult male 01day    691 adult male 05day    694 adult male 30day    826 adult female 01day    1067 adult female 05day    933 adult female 30day    938 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1607 embryo 02-04hr    1770 embryo 04-06hr    1183 embryo 06-08hr    1441 embryo 08-10hr    1236 embryo 10-12hr    1204 embryo 12-14hr    1414 embryo 14-16hr    1974 embryo 16-18hr    1390 embryo 18-20hr    1453 embryo 20-22hr    2585 embryo 22-24hr    1736 larva L1    1023 larva L2    561 larva L3 12hr old    500 larva L3 puffstage 1-2    304 larva L3 puffstage 3-6    1049 larva L3 puffstage 7-9    982 white prepupae new    957 white prepupae 12hr    2198 white prepupae 24hr    1861 pupae 2d postWPP    1596 pupae 3d postWPP    1176 pupae 4d postWPP    678 adult male 01day    691 adult male 05day    694 adult male 30day    826 adult female 01day    1067 adult female 05day    933 adult female 30day    938 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0030505    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0030505 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0030505 expression level Tissue   Expression Level Larval Central Nervous System    24.95 Larval Midgut    16.6 Larval Hindgut    75.2 Larval Malpighian Tubules    37.2 Larval Fat Body    44.5 Larval Salivary Gland    32.5 Larval Trachea    18.1 Larval Carcass    19.625 Adult Head    19.3 Adult Eye    14 Adult Brain    35.4 Adult Thoracic-Abdominal Ganglion    20.3 Adult Crop    21.5 Adult Midgut    9.2 Adult Hindgut    16.1 Adult Malpighian Tubules    24.7 Adult Fat Body    39.9 Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca    17.7 Adult InseminatedFemale Spermatheca    20.7 Adult Ovary    26.5 Adult Testis    9.4 Adult Male Accessory Gland    23.2 Adult Carcass    28.1 Expression Level Scale  None   Low  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    24.95 Larval Midgut    16.6 Larval Hindgut    75.2 Larval Malpighian Tubules    37.2 Larval Fat Body    44.5 Larval Salivary Gland    32.5 Larval Trachea    18.1 Larval Carcass    19.625 Adult Head    19.3 Adult Eye    14 Adult Brain    35.4 Adult Thoracic-Abdominal Ganglion    20.3 Adult Crop    21.5 Adult Midgut    9.2 Adult Hindgut    16.1 Adult Malpighian Tubules    24.7 Adult Fat Body    39.9 Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca    17.7 Adult InseminatedFemale Spermatheca    20.7 Adult Ovary    26.5 Adult Testis    9.4 Adult Male Accessory Gland    23.2 Adult Carcass    28.1 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    24.95 Larval Midgut    16.6 Larval Hindgut    75.2 Larval Malpighian Tubules    37.2 Larval Fat Body    44.5 Larval Salivary Gland    32.5 Larval Trachea    18.1 Larval Carcass    19.625 Adult Head    19.3 Adult Eye    14 Adult Brain    35.4 Adult Thoracic-Abdominal Ganglion    20.3 Adult Crop    21.5 Adult Midgut    9.2 Adult Hindgut    16.1 Adult Malpighian Tubules    24.7 Adult Fat Body    39.9 Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca    17.7 Adult InseminatedFemale Spermatheca    20.7 Adult Ovary    26.5 Adult Testis    9.4 Adult Male Accessory Gland    23.2 Adult Carcass    28.1 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    24.95 Larval Midgut    16.6 Larval Hindgut    75.2 Larval Malpighian Tubules    37.2 Larval Fat Body    44.5 Larval Salivary Gland    32.5 Larval Trachea    18.1 Larval Carcass    19.625 Adult Head    19.3 Adult Eye    14 Adult Brain    35.4 Adult Thoracic-Abdominal Ganglion    20.3 Adult Crop    21.5 Adult Midgut    9.2 Adult Hindgut    16.1 Adult Malpighian Tubules    24.7 Adult Fat Body    39.9 Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca    17.7 Adult InseminatedFemale Spermatheca    20.7 Adult Ovary    26.5 Adult Testis    9.4 Adult Male Accessory Gland    23.2 Adult Carcass    28.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0030505 expression level Tissue   Expression Level Larval Central Nervous System    24.95 Larval Midgut    16.6 Larval Hindgut    75.2 Larval Malpighian Tubules    37.2 Larval Fat Body    44.5 Larval Salivary Gland    32.5 Larval Trachea    18.1 Larval Carcass    19.625 Adult Head    19.3 Adult Eye    14 Adult Brain    35.4 Adult Thoracic-Abdominal Ganglion    20.3 Adult Crop    21.5 Adult Midgut    9.2 Adult Hindgut    16.1 Adult Malpighian Tubules    24.7 Adult Fat Body    39.9 Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca    17.7 Adult InseminatedFemale Spermatheca    20.7 Adult Ovary    26.5 Adult Testis    9.4 Adult Male Accessory Gland    23.2 Adult Carcass    28.1 Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    24.95 Larval Midgut    16.6 Larval Hindgut    75.2 Larval Malpighian Tubules    37.2 Larval Fat Body    44.5 Larval Salivary Gland    32.5 Larval Trachea    18.1 Larval Carcass    19.625 Adult Head    19.3 Adult Eye    14 Adult Brain    35.4 Adult Thoracic-Abdominal Ganglion    20.3 Adult Crop    21.5 Adult Midgut    9.2 Adult Hindgut    16.1 Adult Malpighian Tubules    24.7 Adult Fat Body    39.9 Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca    17.7 Adult InseminatedFemale Spermatheca    20.7 Adult Ovary    26.5 Adult Testis    9.4 Adult Male Accessory Gland    23.2 Adult Carcass    28.1 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    24.95 Larval Midgut    16.6 Larval Hindgut    75.2 Larval Malpighian Tubules    37.2 Larval Fat Body    44.5 Larval Salivary Gland    32.5 Larval Trachea    18.1 Larval Carcass    19.625 Adult Head    19.3 Adult Eye    14 Adult Brain    35.4 Adult Thoracic-Abdominal Ganglion    20.3 Adult Crop    21.5 Adult Midgut    9.2 Adult Hindgut    16.1 Adult Malpighian Tubules    24.7 Adult Fat Body    39.9 Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca    17.7 Adult InseminatedFemale Spermatheca    20.7 Adult Ovary    26.5 Adult Testis    9.4 Adult Male Accessory Gland    23.2 Adult Carcass    28.1 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    24.95 Larval Midgut    16.6 Larval Hindgut    75.2 Larval Malpighian Tubules    37.2 Larval Fat Body    44.5 Larval Salivary Gland    32.5 Larval Trachea    18.1 Larval Carcass    19.625 Adult Head    19.3 Adult Eye    14 Adult Brain    35.4 Adult Thoracic-Abdominal Ganglion    20.3 Adult Crop    21.5 Adult Midgut    9.2 Adult Hindgut    16.1 Adult Malpighian Tubules    24.7 Adult Fat Body    39.9 Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca    17.7 Adult InseminatedFemale Spermatheca    20.7 Adult Ovary    26.5 Adult Testis    9.4 Adult Male Accessory Gland    23.2 Adult Carcass    28.1 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland no informative data Adult Heart no informative data Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    19.3   NA  Eye    14   NA  Brain    35.4   24.95  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    20.3   NA  Crop    21.5   16.6  Midgut    9.2   75.2  Hindgut    16.1   37.2  Malpighian Tubules    24.7   44.5  Fat Body    39.9   32.5  Salivary Gland    no informative data   NA  Heart    no informative data   18.1  Trachea    NA   NA  VirginFemale Spermatheca    17.7   NA  InseminatedFemale Spermatheca    20.7   NA  Ovary    26.5   NA  Testis    9.4   NA  Male Accessory Gland    23.2   19.625  Carcass    28.1 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_27
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030505 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11172-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for NFAT Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 9-10 Stages(s) 11-12 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal, with Scer\GAL4en-e16E NFATEP1335 lethal | recessive NFATPG58 NFATPG128 neurophysiology defective, with Scer\GAL4shakB.lethal.4.1 NFATEP1508 NFATEP19579 semi-viable, with Scer\GAL4Act5C.PI NFATScer\UAS.cHa viable NFATCA07788 NFATEY07123 NFATΔa1 NFATΔa2 NFATΔab NFATΔb viable, with Scer\GAL4[-]: NFATEP1353 viable, with Scer\GAL4pnr-MD237 NFATGD4379 Sterility Allele fertile NFATEY07123 NFATΔa1 NFATΔa2 NFATΔab NFATΔb Other Phenotypes Allele locomotor rhythm defective, with Scer\GAL4elav-C155 NFATEP1508 NFATEP19579 neuroanatomy defective NFATΔab neuroanatomy defective, with Scer\GAL4D42 NFATEP1508 neuroanatomy defective, with Scer\GAL4elav-C155 NFATEP19579 NFATGD4379 neuroanatomy defective, with Scer\GAL4OK6 NFATEP1508 neuroanatomy defective | larval stage, with Scer\GAL4elav-C155 NFATEP1335 NFATEP1353 NFATEP1508 neurophysiology defective NFATΔab neurophysiology defective, with Scer\GAL4elav-C155 NFATEP1508 NFATEP19579 osmotic stress response defective | larval stage NFATΔab visible, with Scer\GAL4ap-md544 NFATEP1508 visible, with Scer\GAL4en-e16E NFATEP1390 visible, with Scer\GAL4ey.PH NFATEP1335 NFATEP1390 NFATEP1508 visible, with Scer\GAL4hs.2sev NFATEP1335 NFATEP1390 NFATEP1508 visible, with Scer\GAL4sca-537.4 NFATEP1335 wild-type, with Scer\GAL4dpp.blk1 NFATScer\UAS.cHa wild-type, with Scer\GAL4vg.PB NFATScer\UAS.cHa Phenotype manifest in Allele anterior fascicle & synapse, with Scer\GAL4elav-C155 NFATEP1335 NFATEP1353 NFATEP1508 dorsocentral bristle, with Scer\GAL4sca-537.4 NFATEP1335 dorsocentral bristle | supernumerary, with Scer\GAL4ap-md544 NFATEP1508 embryonic/larval anal pad NFATΔab eye, with Scer\GAL4ey.PH NFATEP1335 NFATEP1390 NFATEP1508 eye, with Scer\GAL4hs.2sev NFATEP1335 NFATEP1390 NFATEP1508 intersegmental nerve, with Scer\GAL4elav-C155 NFATEP1335 NFATEP1353 NFATEP1508 neuromuscular junction, with Scer\GAL4D42 NFATEP1508 neuromuscular junction, with Scer\GAL4elav-C155 NFATEP1508 NFATGD4379 neuromuscular junction, with Scer\GAL4OK6 NFATEP19579 NFATEP1508 NMJ bouton, with Scer\GAL4elav-C155 NFATEP19579 NFATEP1508 NFATGD4379 pupa, with Scer\GAL4Act5C.PI NFATScer\UAS.cHa RP2 neuron, with Scer\GAL4shakB.lethal.4.1 NFATEP1508 RP neuron, with Scer\GAL4shakB.lethal.4.1 NFATEP19579 scutellar bristle, with Scer\GAL4sca-537.4 NFATEP1335 scutellar bristle | supernumerary, with Scer\GAL4ap-md544 NFATEP1508 synapse NFATΔab synapse, with Scer\GAL4D42 NFATEP19579 NFATEP1508 synapse, with Scer\GAL4elav-C155 NFATEP19579 NFATEP1508 NFATGD4379 trichogen cell, with Scer\GAL4sca-537.4 NFATEP1335 wing vein, with Scer\GAL4en-e16E NFATEP1390 wing vein | supernumerary, with Scer\GAL4ap-md544 NFATEP1508
Classical Alleles ( 45 )
For All Classical Alleles Show
Allele of NFAT Class Mutagen Stocks Known lesion NFAT5-HA-2038 1 -- NFAT5-HA-2877 1 -- NFAT5-SZ-3057 1 -- NFAT5-SZ-4109 1 -- NFATCB-0283-3 1 -- NFATCB-5437-3 1 -- NFATCB-6677-3 1 -- NFATd00242 P-element activity 1 -- NFATd01815 P-element activity 1 -- NFATe00635 piggyBac transposase 1 -- NFATe01645 piggyBac transposase 1 -- NFATe04312 1 -- NFATEP1329 P-element activity 1 -- NFATEP1353 P-element activity 1 Yes NFATEY07123 P-element activity 1 -- NFATNP2272 1 -- NFATNP3346 1 -- NFATNP7183 1 -- NFATΔa1 Delta2-3 1 Yes NFATΔab Delta2-3 1 Yes NFATΔb Delta2-3 1 Yes NFAT5-HA-2076 0 -- NFAT5-HA-2366 0 -- NFATc02371 piggyBac transposase 0 -- NFATCA07788 P-element activity 0 Yes NFATd05301 0 -- NFATd07304 P-element activity 0 -- NFATEP1335 P-element activity 0 Yes NFATEP1390 P-element activity 0 -- NFATEP1508 P-element activity 0 Yes NFATEP1541 P-element activity 0 -- NFATEP19579 0 -- NFATEP805 P-element activity 0 -- NFATF4.24.03 Delta2-3 0 Yes NFATGE02173 0 -- NFATGG01109 0 -- NFATGG01112 0 -- NFATGS229 P-element activity 0 Yes NFATGS250 P-element activity 0 Yes NFATKG04938 P-element activity 0 -- NFATNP4088 0 -- NFATNP6029 0 -- NFATPG128 Delta2-3 0 -- NFATPG58 Delta2-3 0 -- NFATΔa2 Delta2-3 0 Yes
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of NFAT Class Mutagen Stocks Known lesion NFATGD4379 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes NFATKK102385 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes NFATRHD.Scer\UAS in vitro construct - regulatory fusion 0 Yes NFATScer\UAS.cHa in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4379} NA P{KK102385} NA P{UAS-NAFT.RHD} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}NFATEP805 NA P{EP}NFATEP1329 NA P{EP}NFATEP1335 NA P{EP}NFATEP1353 NA P{EP}NFATEP1390 NA P{EP}NFATEP1508 NA P{EP}NFATEP1541 NA P{EP}NFATEP19579 NA P{EPgy2}NFATEY07123 NA P{GSV1}NFATGS229 NA P{GSV1}NFATGS250 NA P{Mae-UAS.6.11}B2014B2014 NA P{Mae-UAS.6.11}B2015B2015 NA P{Mae-UAS.6.11}NFATF4.24.03 NA P{Mae-UAS.6.11}NFATGG01109 NA P{Mae-UAS.6.11}NFATGG01112 NA P{XP}NFATd00242 NA P{XP}NFATd01815 NA P{XP}NFATd05301 NA P{XP}NFATd07304 NA miscellaneous insertions P{PTT-GA}NFATCA07788 NA P{RS3}NFATCB-0283-3 NA P{RS3}NFATCB-5437-3 NA P{RS3}NFATCB-6677-3 NA P{RS5}NFAT5-HA-2038 NA P{RS5}NFAT5-HA-2076 NA P{RS5}NFAT5-HA-2366 NA P{RS5}NFAT5-HA-2877 NA P{RS5}NFAT5-SZ-3057 NA P{RS5}NFAT5-SZ-4109 NA P{SUPor-P}NFATKG04938 NA PBac{PB}NFATc02371 NA PBac{RB}NFATe00635 NA PBac{RB}NFATe01645 NA PBac{RB}NFATe04312 NA insertion of enhancer trap binary system P{GawB}NFATNP2272 No P{GawB}NFATNP3346 No P{GawB}NFATNP4088 No P{GawB}NFATNP6029 No P{GawB}NFATNP7183 No P{GawB}NFATPG58 No P{GawB}NFATPG128 No
Gene Ontology: Function, Process & Cellular Component ( 7 unique terms )
Terms Based on Experimental Evidence ( 2 terms )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
negative regulation of synaptic vesicle exocytosis inferred from direct assay (Freeman et al., 2011) response to salt stress inferred from mutant phenotype (Keyser et al., 2007)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 5 terms )
Molecular Function
CV term Evidence References
binding inferred from electronic annotation with InterPro:IPR011989 (FlyBase Curators et al., 2004-) sequence-specific DNA binding transcription factor activity inferred from sequence or structural similarity (Crabtree, 2000.5.27) inferred from sequence or structural similarity with EMBL:AF162853 (FlyBase, 1992-)
Biological Process
CV term Evidence References
regulation of transcription, DNA-dependent inferred from electronic annotation with InterPro:IPR008366, InterPro:IPR008967, InterPro:IPR011539 (FlyBase Curators et al., 2004-) transcription, DNA-dependent inferred from sequence or structural similarity (Crabtree, 2000.5.27, Huang, 1999.10.18)
Cellular Component
CV term Evidence References
nucleus inferred from sequence or structural similarity (Huang, 1999.10.18) inferred from sequence or structural similarity with EMBL:AF162853 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions NFAT allele Gene References NFATEP805 pnr (Pena-Rangel et al., 2002) NFATEP1329 pnr (Pena-Rangel et al., 2002) NFATEP1335 btl::Egfr (Zhu et al., 2005) Cdc42 (Zhu et al., 2005) CycE (Tseng and Hariharan, 2002) Pvr (Zhu et al., 2005) NFATEP1353 Cdc42 (Zhu et al., 2005) ksr::tor (Huang and Rubin, 2000) pnr (Pena-Rangel et al., 2002) Pvr (Zhu et al., 2005) Ras85D (Huang and Rubin, 2000) NFATEP1390 Cdc42 (Zhu et al., 2005) CycE (Tseng and Hariharan, 2002) Pvr (Zhu et al., 2005) NFATEP1508 Cdc42 (Zhu et al., 2005) pnr (Pena-Rangel et al., 2002) Pvr (Zhu et al., 2005) unspecified ksr (Huang and Rubin, 2000) L (Singh et al., 2005) os (Mukherjee et al., 2006)
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 58698 DroID - A comprehensive database of gene and protein interactions. • FBgn0030505 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32321
Orthologs
Genome-wide drosophilid orthologs	Dana\GF21808 Dere\GG17798 Dgri\GH12805 Dmoj\GI15077 Dper\GL22604 Dpse\GA10815 Dsec\GM17623 Dsim\GD17136 Dvir\GJ18884 Dwil\GK24938 Dyak\GE17094
Curated drosophilid orthologs	Dpse\GA10815
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL011359-PA Aedes aegypti (mosquito) XP_391906.3 Apis mellifera (honey bee) ENSBTAP00000017847 Bos taurus (bovine) ENSCAFP00000030051 Canis familiaris (dog) ENSDARP00000019575 Danio rerio (zebra fish) ENSECAP00000008470 Equus caballus (horse) ENSGALP00000000945 Gallus gallus (chicken) ENSMODP00000003336 Monodelphis domestica (gray opossum) XP_001599457.1 Nasonia vitripennis (wasp) ENSOANP00000003748 Ornithorynchus anatinus (platypus) ENSORLP00000009527 Oryzias latipes (japanese killifish) PHUM008916-PA Pediculus humanus (human body louse) ENSPTRP00000014146 Pan troglodytes (chimpanzee) XP_001177692.1 Strongylocentrotus purpuratus (purple sea urchin) XP_974734.1 Tribolium castaneum (red flour beetle) ENSTNIP00000015072 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000027808 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000038722 Xenopus tropicalis (frog)
Stocks & Reagents
Stocks Listed in FlyBase ( 23 )
Bloomington	36269 w1118 NFATΔb 32652 w1118 NFATΔab 33593 w1118 NFATΔa1 11397 w1118 P{EP}NFATEP1329 19579 w1118 P{EP}NFATEP1353
Harvard	- P{XP}NFATd00242 - P{XP}NFATd01815 - PBac{RB}NFATe00635 - PBac{RB}NFATe01645 - PBac{RB}NFATe04312
VDRC	v107032 P{KK102385}VIE-260B v30566 w1118; P{GD4379}v30566
	More stocks available...
Genomic Clones ( 1 )
	BACR30C16 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 139 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD10950 LD28881 LP14946
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GH07035 GH08553 GM02025 LD23439 LD32208 LD33551 RE22351
Other clones	7846 11161 20146 35710 35908 42723 43520 45840 53326 53425 53502 57403 59033 64429 64779 66789 69999 73208 73966 79745 81047 81071 99356 107862 145652 149283 149295 156454 164558 178041 192858 214289.6 214403.7 214505.7 273507 273706 274620 280469 CK01.2D.E12 CK01.54C.F6 CK01.74D.G7 CK01.75D.G2 CK01.76A.G3 CK01.96B.F2 CK01.98C.A8 CK01.103A.C8 CK01.104B.D4 CK01.105A.G1 CK01.105C.F7 CK01.106A.F4 CK01.106A.G4 CK01.108A.A2 CK01.110C.F7 CK01.115B.D4 CK01.142D.F7 EC15051 EK004035 EK044255 EK058728 EK059357 EK059426 EK060701 EK073503 EK073506 EK073509 EK076204 EK076225 EK079044 EK079846 EK080854 EK083716 EK086644 EK087446 EK087925 EK088224 EK088554 EK088558 EK102716 EK116024 EK134056 EK144404 EK145827 EK145914 EK161508 EK162220 EK162720 EK164828 EK165946 EK170848 EK171035 EK173017 EK173251 EK173335 EK177732 EK182936 EK190051 EK192953 EK195046 EK197415 EK201955 EK203251 EK209828 EK214562 EK214641 EK221814 EK222907 EK227504 EK234248 EK235926 EK244757 EK248104 EK254641 EK254661 EK259452 EK290516 EK295516 EK302242 EK305350 EP02543 EP10104 EP16659 EP18711 LD12674 MB6-CG11172-RA RP004109042 RP004206902 RP004212659 RP004233714 RP004256317
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030505 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32321
Antibody Information
	polyclonal (Freeman et al., 2011)
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: NFAT CG11172 (FlyBase, 1996-)
Source for database merge of	Source for merge of: NFAT EP1335 MESR1 (Kraut et al., 2001)
Additional comments	Source for identity of NFAT CG11172 was sequence comparison (date:001108). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_078592 NM_001103504 NM_001169274 NM_001169275 NM_001169276 RefSeq (Proteins) • NP_511147 NP_001096974 NP_001162745 NP_001162746 NP_001162747 DDBJ / EMBL / GenBank • AA391997 AA950353 AAF48297 AAG28468 AAO40817 AAT94496 ABW09408 ACZ95280 ACZ95281 ACZ95282 AF195496 AQ025361 AQ025413 AQ025433 AQ073194 AQ073198 AQ073228 AQ073251 AW942165 BH740834 BH740835 BT003742 BT015267 CL706570 CZ467895 CZ471477 CZ472456 CZ475653 CZ478499 CZ479450 Entrez Gene - A searchable database of RefSeq genes. • 32321 UniProtKB/TrEMBL • A8JUV3 E1JJP5 E1JJP6 Q9GU53 Q9VYA6 Q86NT0
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Cell surface receptor IPT/TIG (IPR002909) Nuclear factor of activated T cells (NFAT) (IPR008366) p53-like transcription factor, DNA-binding (IPR008967) Rel homology (IPR011539) Immunoglobulin-like fold (IPR013783) Immunoglobulin E-set (IPR014756) Armadillo-like helical (IPR011989)
Linkouts
	BioGRID - A database of protein and genetic interactions • 58698 DroID - A comprehensive database of gene and protein interactions. • FBgn0030505 DRSC - Results from RNAi screens. • FBgn0030505 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030505 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG11172-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030505 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32321 InParanoid A subset of ortholog calls from InParanoid. • AAEL011359-PA Aedes aegypti (mosquito) XP_391906.3 Apis mellifera (honey bee) ENSBTAP00000017847 Bos taurus (bovine) ENSCAFP00000030051 Canis familiaris (dog) ENSDARP00000019575 Danio rerio (zebra fish) ENSECAP00000008470 Equus caballus (horse) ENSGALP00000000945 Gallus gallus (chicken) ENSMODP00000003336 Monodelphis domestica (gray opossum) XP_001599457.1 Nasonia vitripennis (wasp) ENSOANP00000003748 Ornithorynchus anatinus (platypus) ENSORLP00000009527 Oryzias latipes (japanese killifish) PHUM008916-PA Pediculus humanus (human body louse) ENSPTRP00000014146 Pan troglodytes (chimpanzee) XP_001177692.1 Strongylocentrotus purpuratus (purple sea urchin) XP_974734.1 Tribolium castaneum (red flour beetle) ENSTNIP00000015072 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000027808 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000038722 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32321 modMine - Data generated by the modENCODE project. • FBgn0030505
Synonyms & Secondary IDs ( 11 )
Reported As
Symbol Synonym	CG11172 (Tseng and Hariharan, 2002, Bourbon et al., 2002, Kraut et al., 2001, Kraut et al., 2001, Crabtree, 2000.5.27, Keleman et al., 2009.8.5, Freeman et al., 2011) dNFAT (Huang, 1999.10.18) EP1335 (Kraut et al., 2001, Kraut et al., 2001, Abdelilah-Seyfried et al., 2000, ) MESR1 (Huang and Rubin, 2000, ) NFAT (Rehwinkel et al., 2006, Robinson, 2006, Mukherjee et al., 2006, Buszczak et al., 2007, Grieder et al., 2007, Bilen and Bonini, 2007, Keyser et al., 2007, Freeman et al., 2011, Seong et al., 2011, Reis et al., 2010) NF-AT5 (Keyser et al., 2001) NFAT5 (Graef et al., 2001)
Name Synonym	Drosophila TonEBP (Graef et al., 2001) Misexpression Suppressor of Ras 1 (Huntley and Golding, 2004, ) NFAT (Bilen and Bonini, 2007) NFAT homolog   Rel domain protein (Kraut et al., 2001, Kraut et al., 2001)
Secondary FlyBase IDs
	FBgn0043371 FBgn0043579
References ( 45 )
Generate a list of	All references relating to this gene ( 45 )
List References by type	Research paper  ( 21 ) Supplementary material  ( 5 ) Review  ( 1 ) Personal communication to FlyBase  ( 7 ) Abstract  ( 3 ) FlyBase analysis  ( 3 ) DNA/RNA sequence record  ( 1 ) Computer file  ( 3 ) Automatic genome annotation  ( 1 )
Recent research papers ( 4 )
	Carreira et al., 2011, BMC Dev. Biol. 11: 32 Genetic basis of wing morphogenesis in Drosophila: sexual dimorphism and non-allometric effects of shape variation. [FBrf0214273] Freeman et al., 2011, Mol. Cell. Neurosci. 46(2): 535--547 NFAT regulates pre-synaptic development and activity-dependent plasticity in Drosophila. [FBrf0212894] Seong et al., 2011, Biogerontology 12(2): 93--107 Genome-wide analysis of low-dose irradiated male Drosophila melanogaster with extended longevity. [FBrf0213307] Reis et al., 2010, PLoS Genet. 6(11): e1001206 A buoyancy-based screen of Drosophila larvae for fat-storage mutants reveals a role for sir2 in coupling fat storage to nutrient availability. [FBrf0212335] Show all research papers ...
Recent reviews (0)
	All reviews listed in FlyBase were published before 2010 Show reviews ...