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Gene Dmel\mRpL38

General Information
Symbol	Dmel\mRpL38	Species	D. melanogaster
Name	mitochondrial ribosomal protein L38	Annotation symbol	CG15871
Feature type	protein_coding_gene	FlyBase ID	FBgn0030552
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	12E5-12E5	Sequence location	X:14,120,324..14,121,983 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene mitochondrial ribosomal protein L38 is referred to in FlyBase by the symbol Dmel\mRpL38 (CG15871, FBgn0030552). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: phosphatidylethanolamine binding; structural constituent of ribosome. Based on sequence similarity, it is predicted to be involved in the biological process: translation. One allele is reported. The phenotype of this allele is annotated with: trichogen cell. It has one annotated transcript and one annotated polypeptide. Protein features are: Phosphatidylethanolamine-binding protein PEBP. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during early larval stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1638073_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of mRpL38. Gene sequence location is X:14120324..14121983.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	Controlled Vocabulary Terms day 42 of adulthood day 41 of adulthood day 30 of adulthood day 49 of adulthood day 17 of adulthood day 45 of adulthood day 8 of adulthood day 26 of adulthood day 21 of adulthood day 13 of adulthood day 25 of adulthood day 20 of adulthood day 22 of adulthood day 39 of adulthood day 7 of adulthood day 36 of adulthood day 11 of adulthood day 37 of adulthood day 27 of adulthood day 18 of adulthood day 19 of adulthood day 28 of adulthood day 9 of adulthood day 29 of adulthood adult heart day 40 of adulthood day 16 of adulthood day 24 of adulthood day 15 of adulthood day 33 of adulthood day 43 of adulthood day 47 of adulthood day 38 of adulthood day 32 of adulthood day 48 of adulthood day 23 of adulthood day 35 of adulthood day 12 of adulthood day 10 of adulthood day 31 of adulthood day 34 of adulthood day 44 of adulthood day 14 of adulthood day 46 of adulthood
FB2012_01	Sequence features HFA19734 BKN22659
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 12E5-12E5   Limits computationally determined from genome sequence between P{EP}l(1)G0007EP764 and P{EP}EP1599
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\mRpL38 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) mRpL38-RA FBtr0073902  NM_078597   1398   416
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein mRpL38-PA   FBpp0073719   47.8   416   9.45     NP_511152   AAF48357
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Phosphatidylethanolamine-binding protein PEBP (IPR008914)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF48357   AI296980   AY071580 AAL49202   BI166849   BI166977   BI353737   BI354868   BI355360   BI373582   BI375758   BI484420   BI486917   BI487244   BI564612   BT022635   CK135698   CO186322   CO278094   CO315988   CO327613   CO330295   EC067432   EC084045   EC086247   EC089338   EC201391
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VY48
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0030552    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0030552 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during early larval stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0030552 expression level Developmental Stage   Expression Level embryo 00-02hr    3270 embryo 02-04hr    553 embryo 04-06hr    1727 embryo 06-08hr    2194 embryo 08-10hr    2161 embryo 10-12hr    3056 embryo 12-14hr    2606 embryo 14-16hr    3535 embryo 16-18hr    3668 embryo 18-20hr    3947 embryo 20-22hr    3129 embryo 22-24hr    2770 larva L1    3971 larva L2    4175 larva L3 12hr old    2797 larva L3 puffstage 1-2    1155 larva L3 puffstage 3-6    1191 larva L3 puffstage 7-9    1139 white prepupae new    1064 white prepupae 12hr    1189 white prepupae 24hr    1188 pupae 2d postWPP    2485 pupae 3d postWPP    2962 pupae 4d postWPP    1641 adult male 01day    1530 adult male 05day    1507 adult male 30day    1538 adult female 01day    2788 adult female 05day    3108 adult female 30day    3318 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3270) embryo 02-04hr  (553) embryo 04-06hr  (1727) embryo 06-08hr  (2194) embryo 08-10hr  (2161) embryo 10-12hr  (3056) embryo 12-14hr  (2606) embryo 14-16hr  (3535) embryo 16-18hr  (3668) embryo 18-20hr  (3947) embryo 20-22hr  (3129) embryo 22-24hr  (2770) larva L1  (3971) larva L2  (4175) larva L3 12hr old  (2797) larva L3 puffstage 1-2  (1155) larva L3 puffstage 3-6  (1191) larva L3 puffstage 7-9  (1139) white prepupae new  (1064) white prepupae 12hr  (1189) white prepupae 24hr  (1188) pupae 2d postWPP  (2485) pupae 3d postWPP  (2962) pupae 4d postWPP  (1641) adult male 01day  (1530) adult male 05day  (1507) adult male 30day  (1538) adult female 01day  (2788) adult female 05day  (3108) adult female 30day  (3318) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3270) embryo 02-04hr    553 embryo 04-06hr  (1727) embryo 06-08hr  (2194) embryo 08-10hr  (2161) embryo 10-12hr  (3056) embryo 12-14hr  (2606) embryo 14-16hr  (3535) embryo 16-18hr  (3668) embryo 18-20hr  (3947) embryo 20-22hr  (3129) embryo 22-24hr  (2770) larva L1  (3971) larva L2  (4175) larva L3 12hr old  (2797) larva L3 puffstage 1-2    1155 larva L3 puffstage 3-6    1191 larva L3 puffstage 7-9    1139 white prepupae new    1064 white prepupae 12hr    1189 white prepupae 24hr    1188 pupae 2d postWPP  (2485) pupae 3d postWPP  (2962) pupae 4d postWPP  (1641) adult male 01day  (1530) adult male 05day  1507 adult male 30day  (1538) adult female 01day  (2788) adult female 05day  (3108) adult female 30day  (3318) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3270 embryo 02-04hr    553 embryo 04-06hr    1727 embryo 06-08hr    2194 embryo 08-10hr    2161 embryo 10-12hr    3056 embryo 12-14hr    2606 embryo 14-16hr    3535 embryo 16-18hr    3668 embryo 18-20hr    3947 embryo 20-22hr    3129 embryo 22-24hr    2770 larva L1    3971 larva L2    4175 larva L3 12hr old    2797 larva L3 puffstage 1-2    1155 larva L3 puffstage 3-6    1191 larva L3 puffstage 7-9    1139 white prepupae new    1064 white prepupae 12hr    1189 white prepupae 24hr    1188 pupae 2d postWPP    2485 pupae 3d postWPP    2962 pupae 4d postWPP    1641 adult male 01day    1530 adult male 05day    1507 adult male 30day    1538 adult female 01day    2788 adult female 05day    3108 adult female 30day    3318 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3270 embryo 02-04hr    553 embryo 04-06hr    1727 embryo 06-08hr    2194 embryo 08-10hr    2161 embryo 10-12hr    3056 embryo 12-14hr    2606 embryo 14-16hr    3535 embryo 16-18hr    3668 embryo 18-20hr    3947 embryo 20-22hr    3129 embryo 22-24hr    2770 larva L1    3971 larva L2    4175 larva L3 12hr old    2797 larva L3 puffstage 1-2    1155 larva L3 puffstage 3-6    1191 larva L3 puffstage 7-9    1139 white prepupae new    1064 white prepupae 12hr    1189 white prepupae 24hr    1188 pupae 2d postWPP    2485 pupae 3d postWPP    2962 pupae 4d postWPP    1641 adult male 01day    1530 adult male 05day    1507 adult male 30day    1538 adult female 01day    2788 adult female 05day    3108 adult female 30day    3318 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0030552 expression level Developmental Stage   Expression Level embryo 00-02hr    3270 embryo 02-04hr    553 embryo 04-06hr    1727 embryo 06-08hr    2194 embryo 08-10hr    2161 embryo 10-12hr    3056 embryo 12-14hr    2606 embryo 14-16hr    3535 embryo 16-18hr    3668 embryo 18-20hr    3947 embryo 20-22hr    3129 embryo 22-24hr    2770 larva L1    3971 larva L2    4175 larva L3 12hr old    2797 larva L3 puffstage 1-2    1155 larva L3 puffstage 3-6    1191 larva L3 puffstage 7-9    1139 white prepupae new    1064 white prepupae 12hr    1189 white prepupae 24hr    1188 pupae 2d postWPP    2485 pupae 3d postWPP    2962 pupae 4d postWPP    1641 adult male 01day    1530 adult male 05day    1507 adult male 30day    1538 adult female 01day    2788 adult female 05day    3108 adult female 30day    3318 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3270) embryo 02-04hr  (553) embryo 04-06hr  (1727) embryo 06-08hr  (2194) embryo 08-10hr  (2161) embryo 10-12hr  (3056) embryo 12-14hr  (2606) embryo 14-16hr  (3535) embryo 16-18hr  (3668) embryo 18-20hr  (3947) embryo 20-22hr  (3129) embryo 22-24hr  (2770) larva L1  (3971) larva L2  (4175) larva L3 12hr old  (2797) larva L3 puffstage 1-2  (1155) larva L3 puffstage 3-6  (1191) larva L3 puffstage 7-9  (1139) white prepupae new  (1064) white prepupae 12hr  (1189) white prepupae 24hr  (1188) pupae 2d postWPP  (2485) pupae 3d postWPP  (2962) pupae 4d postWPP  (1641) adult male 01day  (1530) adult male 05day  (1507) adult male 30day  (1538) adult female 01day  (2788) adult female 05day  (3108) adult female 30day  (3318) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3270) embryo 02-04hr    553 embryo 04-06hr  1727 embryo 06-08hr  2194 embryo 08-10hr  2161 embryo 10-12hr  (3056) embryo 12-14hr  (2606) embryo 14-16hr  (3535) embryo 16-18hr  (3668) embryo 18-20hr  (3947) embryo 20-22hr  (3129) embryo 22-24hr  (2770) larva L1  (3971) larva L2  (4175) larva L3 12hr old  (2797) larva L3 puffstage 1-2    1155 larva L3 puffstage 3-6    1191 larva L3 puffstage 7-9    1139 white prepupae new    1064 white prepupae 12hr    1189 white prepupae 24hr    1188 pupae 2d postWPP  (2485) pupae 3d postWPP  (2962) pupae 4d postWPP  1641 adult male 01day  1530 adult male 05day  1507 adult male 30day  1538 adult female 01day  (2788) adult female 05day  (3108) adult female 30day  (3318) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3270 embryo 02-04hr    553 embryo 04-06hr    1727 embryo 06-08hr    2194 embryo 08-10hr    2161 embryo 10-12hr    3056 embryo 12-14hr    2606 embryo 14-16hr    3535 embryo 16-18hr    3668 embryo 18-20hr    3947 embryo 20-22hr    3129 embryo 22-24hr    2770 larva L1    3971 larva L2    4175 larva L3 12hr old    2797 larva L3 puffstage 1-2    1155 larva L3 puffstage 3-6    1191 larva L3 puffstage 7-9    1139 white prepupae new    1064 white prepupae 12hr    1189 white prepupae 24hr    1188 pupae 2d postWPP    2485 pupae 3d postWPP    2962 pupae 4d postWPP    1641 adult male 01day    1530 adult male 05day    1507 adult male 30day    1538 adult female 01day    2788 adult female 05day    3108 adult female 30day    3318 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3270 embryo 02-04hr    553 embryo 04-06hr    1727 embryo 06-08hr    2194 embryo 08-10hr    2161 embryo 10-12hr    3056 embryo 12-14hr    2606 embryo 14-16hr    3535 embryo 16-18hr    3668 embryo 18-20hr    3947 embryo 20-22hr    3129 embryo 22-24hr    2770 larva L1    3971 larva L2    4175 larva L3 12hr old    2797 larva L3 puffstage 1-2    1155 larva L3 puffstage 3-6    1191 larva L3 puffstage 7-9    1139 white prepupae new    1064 white prepupae 12hr    1189 white prepupae 24hr    1188 pupae 2d postWPP    2485 pupae 3d postWPP    2962 pupae 4d postWPP    1641 adult male 01day    1530 adult male 05day    1507 adult male 30day    1538 adult female 01day    2788 adult female 05day    3108 adult female 30day    3318 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0030552    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0030552 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0030552 expression level Tissue   Expression Level Larval Central Nervous System    207.025 Larval Midgut    90.9 Larval Hindgut    228 Larval Malpighian Tubules    104.6 Larval Fat Body    120.3 Larval Salivary Gland    155.1 Larval Trachea    222.725 Larval Carcass    111.275 Adult Head    166.7 Adult Eye    189.6 Adult Brain    247 Adult Thoracic-Abdominal Ganglion    248.6 Adult Crop    176 Adult Midgut    148.8 Adult Hindgut    204.4 Adult Malpighian Tubules    82 Adult Fat Body    184.6 Adult Salivary Gland    103.1 Adult Heart    207.825 Adult VirginFemale Spermatheca    78.6 Adult InseminatedFemale Spermatheca    85.7 Adult Ovary    338.5 Adult Testis    57.8 Adult Male Accessory Gland    103.1 Adult Carcass    219.9 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    207.025 Larval Midgut    90.9 Larval Hindgut    228 Larval Malpighian Tubules    104.6 Larval Fat Body    120.3 Larval Salivary Gland    155.1 Larval Trachea    222.725 Larval Carcass    111.275 Adult Head    166.7 Adult Eye    189.6 Adult Brain    247 Adult Thoracic-Abdominal Ganglion    248.6 Adult Crop    176 Adult Midgut    148.8 Adult Hindgut    204.4 Adult Malpighian Tubules    82 Adult Fat Body    184.6 Adult Salivary Gland    103.1 Adult Heart    207.825 Adult VirginFemale Spermatheca    78.6 Adult InseminatedFemale Spermatheca    85.7 Adult Ovary    338.5 Adult Testis    57.8 Adult Male Accessory Gland    103.1 Adult Carcass    219.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    207.025 Larval Midgut    90.9 Larval Hindgut    228 Larval Malpighian Tubules    104.6 Larval Fat Body    120.3 Larval Salivary Gland    155.1 Larval Trachea    222.725 Larval Carcass    111.275 Adult Head    166.7 Adult Eye    189.6 Adult Brain    247 Adult Thoracic-Abdominal Ganglion    248.6 Adult Crop    176 Adult Midgut    148.8 Adult Hindgut    204.4 Adult Malpighian Tubules    82 Adult Fat Body    184.6 Adult Salivary Gland    103.1 Adult Heart    207.825 Adult VirginFemale Spermatheca    78.6 Adult InseminatedFemale Spermatheca    85.7 Adult Ovary    338.5 Adult Testis    57.8 Adult Male Accessory Gland    103.1 Adult Carcass    219.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    207.025 Larval Midgut    90.9 Larval Hindgut    228 Larval Malpighian Tubules    104.6 Larval Fat Body    120.3 Larval Salivary Gland    155.1 Larval Trachea    222.725 Larval Carcass    111.275 Adult Head    166.7 Adult Eye    189.6 Adult Brain    247 Adult Thoracic-Abdominal Ganglion    248.6 Adult Crop    176 Adult Midgut    148.8 Adult Hindgut    204.4 Adult Malpighian Tubules    82 Adult Fat Body    184.6 Adult Salivary Gland    103.1 Adult Heart    207.825 Adult VirginFemale Spermatheca    78.6 Adult InseminatedFemale Spermatheca    85.7 Adult Ovary    338.5 Adult Testis    57.8 Adult Male Accessory Gland    103.1 Adult Carcass    219.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0030552 expression level Tissue   Expression Level Larval Central Nervous System    207.025 Larval Midgut    90.9 Larval Hindgut    228 Larval Malpighian Tubules    104.6 Larval Fat Body    120.3 Larval Salivary Gland    155.1 Larval Trachea    222.725 Larval Carcass    111.275 Adult Head    166.7 Adult Eye    189.6 Adult Brain    247 Adult Thoracic-Abdominal Ganglion    248.6 Adult Crop    176 Adult Midgut    148.8 Adult Hindgut    204.4 Adult Malpighian Tubules    82 Adult Fat Body    184.6 Adult Salivary Gland    103.1 Adult Heart    207.825 Adult VirginFemale Spermatheca    78.6 Adult InseminatedFemale Spermatheca    85.7 Adult Ovary    338.5 Adult Testis    57.8 Adult Male Accessory Gland    103.1 Adult Carcass    219.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    207.025 Larval Midgut    90.9 Larval Hindgut    228 Larval Malpighian Tubules    104.6 Larval Fat Body    120.3 Larval Salivary Gland    155.1 Larval Trachea    222.725 Larval Carcass    111.275 Adult Head    166.7 Adult Eye    189.6 Adult Brain    247 Adult Thoracic-Abdominal Ganglion    248.6 Adult Crop    176 Adult Midgut    148.8 Adult Hindgut    204.4 Adult Malpighian Tubules    82 Adult Fat Body    184.6 Adult Salivary Gland    103.1 Adult Heart    207.825 Adult VirginFemale Spermatheca    78.6 Adult InseminatedFemale Spermatheca    85.7 Adult Ovary    338.5 Adult Testis    57.8 Adult Male Accessory Gland    103.1 Adult Carcass    219.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    207.025 Larval Midgut    90.9 Larval Hindgut    228 Larval Malpighian Tubules    104.6 Larval Fat Body    120.3 Larval Salivary Gland    155.1 Larval Trachea    222.725 Larval Carcass    111.275 Adult Head    166.7 Adult Eye    189.6 Adult Brain    247 Adult Thoracic-Abdominal Ganglion    248.6 Adult Crop    176 Adult Midgut    148.8 Adult Hindgut    204.4 Adult Malpighian Tubules    82 Adult Fat Body    184.6 Adult Salivary Gland    103.1 Adult Heart    207.825 Adult VirginFemale Spermatheca    78.6 Adult InseminatedFemale Spermatheca    85.7 Adult Ovary    338.5 Adult Testis    57.8 Adult Male Accessory Gland    103.1 Adult Carcass    219.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    207.025 Larval Midgut    90.9 Larval Hindgut    228 Larval Malpighian Tubules    104.6 Larval Fat Body    120.3 Larval Salivary Gland    155.1 Larval Trachea    222.725 Larval Carcass    111.275 Adult Head    166.7 Adult Eye    189.6 Adult Brain    247 Adult Thoracic-Abdominal Ganglion    248.6 Adult Crop    176 Adult Midgut    148.8 Adult Hindgut    204.4 Adult Malpighian Tubules    82 Adult Fat Body    184.6 Adult Salivary Gland    103.1 Adult Heart    207.825 Adult VirginFemale Spermatheca    78.6 Adult InseminatedFemale Spermatheca    85.7 Adult Ovary    338.5 Adult Testis    57.8 Adult Male Accessory Gland    103.1 Adult Carcass    219.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    166.7   NA  Eye    189.6   NA  Brain    247   207.025  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    248.6   NA  Crop    176   90.9  Midgut    148.8   228  Hindgut    204.4   104.6  Malpighian Tubules    82   120.3  Fat Body    184.6   155.1  Salivary Gland    103.1   NA  Heart    207.825   222.725  Trachea    NA   NA  VirginFemale Spermatheca    78.6   NA  InseminatedFemale Spermatheca    85.7   NA  Ovary    338.5   NA  Testis    57.8   NA  Male Accessory Gland    103.1   111.275  Carcass    219.9 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_19
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030552 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG15871-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 mRpL38GD9136 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 mRpL38GD9136 Phenotype manifest in Allele trichogen cell, with Scer\GAL4pnr-MD237 mRpL38GD9136
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of mRpL38 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of mRpL38 Class Mutagen Stocks Known lesion mRpL38GD9136 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD9136} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
phosphatidylethanolamine binding inferred from sequence or structural similarity with EMBL:AF016423 (FlyBase, 1992-) structural constituent of ribosome inferred from sequence or structural similarity with EMBL:AI074410 (Suzuki et al., 2001)
Biological Process
CV term Evidence References
translation inferred from sequence or structural similarity with EMBL:AI074410 (Suzuki et al., 2001)
Cellular Component
CV term Evidence References
mitochondrial large ribosomal subunit inferred from sequence or structural similarity with EMBL:AI074410 (Suzuki et al., 2001)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions mRpL38 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 58742 DroID - A comprehensive database of gene and protein interactions. • FBgn0030552 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32375
Orthologs
Genome-wide drosophilid orthologs	Dana\GF15958 Dere\GG17835 Dgri\GH12376 Dmoj\GI14755 Dper\GL12995 Dpse\GA13994 Dsec\GM17664 Dsim\GD17162 Dvir\GJ19158 Dwil\GK25755 Dyak\GE17128
Curated drosophilid orthologs	Dpse\GA13994
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL011198-PA Aedes aegypti (mosquito) AGAP000652-PA Anopheles gambiae (mosquito) XP_394204.2 Apis mellifera (honey bee) XP_001952115.1 Acyrthosiphon pisum (pea aphid) 118800 Branchiostoma floridae (lancelet) BGIBMGA010593-PA Bombyx mori (silk worm) ENSBTAP00000050302 Bos taurus (bovine) CN13090 Caenorhabditis brenneri (small nematode) CN24436 Caenorhabditis brenneri (small nematode) CBP05266 Caenorhabditis briggsae (nematode) CE27249 Caenorhabditis elegans (worm) ENSCAFP00000007381 Canis familiaris (dog) ENSCINP00000002414 Ciona intestinalis (sea squirt) JA07714 Caenorhabditis japonica (nematode) CPIJ009811 Culex pipens (mosquito) ENSCPOP00000017922 Cavia porcellus (guinea pig) RP12508 Caenorhabditis remanei (nematode) ENSCSAVP00000005092 Ciona savignyi (sedentary tunicate) 150382 Capitella spl (polychaete worm) 41519 Daphnia pulex (daphnia) ENSDARP00000057982 Danio rerio (zebra fish) ENSECAP00000012373 Equus caballus (horse) ENSGACP00000006808 Gymnopilus aculeatus (mushroom) ENSGALP00000003428 Gallus gallus (chicken) 80148 Hypsipyla robusta (cedar shoot borer) ENSP00000387085 Homo sapiens (human) ISCW021329-PA Ixodes scapularis (deer tick) 134046 Lottia gigantea (owl limpet) 26154 Monocosta brevicollis (choanoflagellate) ENSMODP00000009652 Monodelphis domestica (gray opossum) ENSMUSP00000102047 Mus musculus (house mouse) 128450 Nematostella vectensis (starlet anemone) XP_001604304.1 Nasonia vitripennis (wasp) ENSOANP00000002956 Ornithorynchus anatinus (platypus) PHUM003349-PA Pediculus humanus (human body louse) PP11006 Pristionchus pacificus (nematode) ENSPPYP00000009704 Pongo pygmaeus (orangutan) ENSPTRP00000016418 Pan troglodytes (chimpanzee) ENSRNOP00000011328 Rattus norvegicus (norway rat) Smp_050700 Schistosoma mansoni (trematode parasite) XP_001202147.1 Strongylocentrotus purpuratus (purple sea urchin) 55510 Trichoplax adhaerens (metazoa) XP_967732.1 Tribolium castaneum (red flour beetle) ENSTRUP00000019985 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000036948 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17533 NV13295 LH19295 ISCW021329 FBgn0234609 FBgn0227714 FBgn0206303 FBgn0188731 FBgn0172572 JGI_V11_41519 FBgn0074026 FBgn0157574 FBgn0150601 FBgn0137506 FBgn0119855 FBgn0110056 FBgn0092981 CPIJ009811 BGIBMGA010593 ACYPI008716 GB15475 AGAP000652 AAEL011198 PHUM580880 GLEAN_02530
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v43691 w1118; P{GD9136}v43691/TM3 v43692 w1118; P{GD9136}v43692/CyO
Genomic Clones ( 1 )
	BACR12J05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 23 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	IP07725 RE63629
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM24925 GM28657 GM30522 LP11117 RE07075 RE07239 RE60912 RE67520 RE70404 RE70775
Other clones	17128 65791 75323 160329 191831 EK018731 EK128733 EK263264 EK294920 EP07707 RH61928
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030552 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32375
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: mRpL3a CG15871 (Suzuki et al., 2001)
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_078597 RefSeq (Proteins) • NP_511152 DDBJ / EMBL / GenBank • AAF48357 AAL49202 AY071580 BI375758 Entrez Gene - A searchable database of RefSeq genes. • 32375 UniProtKB/TrEMBL • Q9VY48
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Phosphatidylethanolamine-binding protein PEBP (IPR008914)
Linkouts
	BioGRID - A database of protein and genetic interactions • 58742 DroID - A comprehensive database of gene and protein interactions. • FBgn0030552 DRSC - Results from RNAi screens. • FBgn0030552 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030552 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG15871-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030552 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32375 InParanoid A subset of ortholog calls from InParanoid. • AAEL011198-PA Aedes aegypti (mosquito) AGAP000652-PA Anopheles gambiae (mosquito) XP_394204.2 Apis mellifera (honey bee) XP_001952115.1 Acyrthosiphon pisum (pea aphid) 118800 Branchiostoma floridae (lancelet) BGIBMGA010593-PA Bombyx mori (silk worm) ENSBTAP00000050302 Bos taurus (bovine) CN13090 Caenorhabditis brenneri (small nematode) CN24436 Caenorhabditis brenneri (small nematode) CBP05266 Caenorhabditis briggsae (nematode) CE27249 Caenorhabditis elegans (worm) ENSCAFP00000007381 Canis familiaris (dog) ENSCINP00000002414 Ciona intestinalis (sea squirt) JA07714 Caenorhabditis japonica (nematode) CPIJ009811 Culex pipens (mosquito) ENSCPOP00000017922 Cavia porcellus (guinea pig) RP12508 Caenorhabditis remanei (nematode) ENSCSAVP00000005092 Ciona savignyi (sedentary tunicate) 150382 Capitella spl (polychaete worm) 41519 Daphnia pulex (daphnia) ENSDARP00000057982 Danio rerio (zebra fish) ENSECAP00000012373 Equus caballus (horse) ENSGACP00000006808 Gymnopilus aculeatus (mushroom) ENSGALP00000003428 Gallus gallus (chicken) 80148 Hypsipyla robusta (cedar shoot borer) ENSP00000387085 Homo sapiens (human) ISCW021329-PA Ixodes scapularis (deer tick) 134046 Lottia gigantea (owl limpet) 26154 Monocosta brevicollis (choanoflagellate) ENSMODP00000009652 Monodelphis domestica (gray opossum) ENSMUSP00000102047 Mus musculus (house mouse) 128450 Nematostella vectensis (starlet anemone) XP_001604304.1 Nasonia vitripennis (wasp) ENSOANP00000002956 Ornithorynchus anatinus (platypus) PHUM003349-PA Pediculus humanus (human body louse) PP11006 Pristionchus pacificus (nematode) ENSPPYP00000009704 Pongo pygmaeus (orangutan) ENSPTRP00000016418 Pan troglodytes (chimpanzee) ENSRNOP00000011328 Rattus norvegicus (norway rat) Smp_050700 Schistosoma mansoni (trematode parasite) XP_001202147.1 Strongylocentrotus purpuratus (purple sea urchin) 55510 Trichoplax adhaerens (metazoa) XP_967732.1 Tribolium castaneum (red flour beetle) ENSTRUP00000019985 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000036948 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32375 modMine - Data generated by the modENCODE project. • FBgn0030552 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB17533 NV13295 LH19295 ISCW021329 FBgn0234609 FBgn0227714 FBgn0206303 FBgn0188731 FBgn0172572 JGI_V11_41519 FBgn0074026 FBgn0157574 FBgn0150601 FBgn0137506 FBgn0119855 FBgn0110056 FBgn0092981 CPIJ009811 BGIBMGA010593 ACYPI008716 GB15475 AGAP000652 AAEL011198 PHUM580880 GLEAN_02530
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	CG15871 (Marygold et al., 2007, Cammarato et al., 2011) MRP-L3 (Suzuki et al., 2001) mRpL3a   mRpL38 (Marygold et al., 2007)
Name Synonym	mitochondrial ribosomal protein L3a (Suzuki et al., 2001) mitochondrial ribosomal protein L38 (Marygold, 2004.9.8, Cammarato et al., 2011)
Secondary FlyBase IDs
References ( 13 )
Research paper	Marygold et al., 2007, Genome Biol. 8(10): R216 The ribosomal protein genes and Minute loci of Drosophila melanogaster. [FBrf0205398] Suzuki et al., 2001, J. Biol. Chem. 276(24): 21724--21736 Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. [FBrf0136752]
Supplementary material	Cammarato et al., 2011, PLoS ONE 6(4): Table S1. Proteins & Peptides. [FBrf0214682] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Marygold, 2004.9.8, Ribosomal protein nomenclature in D.melanogaster. Ribosomal protein nomenclature in D.melanogaster. [FBrf0179760]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
Curated genome annotation	Milshina, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126686]