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Gene Dmel\mRpL38

General Information
Symbol	Dmel\mRpL38	Species	D. melanogaster
Name	mitochondrial ribosomal protein L38	Annotation symbol	CG15871
Feature type	protein_coding_gene	FlyBase ID	FBgn0030552
Gene Model Status	Current	Stock availability	2 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	12E5-12E5	Sequence location	X:14,120,322..14,121,982 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene mitochondrial ribosomal protein L38 is referred to in FlyBase by the symbol Dmel\mRpL38 (CG15871, FBgn0030552). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: phosphatidylethanolamine binding; structural constituent of ribosome. Based on sequence similarity, it is predicted to be involved in the biological process: translation. 2 alleles are reported. The phenotype of these alleles is annotated with: trichogen cell. It has one annotated transcript and one annotated polypeptide. Protein features are: Phosphatidylethanolamine-binding protein PEBP. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during early larval stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1638073_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of mRpL38. Gene sequence location is X:14120324..14121983.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 12E5-12E5   Limits computationally determined from genome sequence between P{EP}l(1)G0007EP764 and P{EP}EP1599
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\mRpL38 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.51
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) mRpL38-RA FBtr0073902  NM_078597   1399   416
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein mRpL38-PA   FBpp0073719   47.8   416   9.45     NP_511152   AAF48357
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Phosphatidylethanolamine-binding protein PEBP (IPR008914)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF48357   AI296980   AY071580 AAL49202   BI166849   BI166977   BI353737   BI354868   BI355360   BI373582   BI375758   BI484420   BI486917   BI487244   BI564612   BT022635   CK135698   CO186322   CO278094   CO315988   CO327613   CO330295   EC067432   EC084045   EC086247   EC089338   EC201391
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VY48
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, adult midgut, larval/adult hindgut, larval Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult ovary, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    207.025 Larval Midgut    90.9 Larval Hindgut    228 Larval Malpighian Tubules    104.6 Larval Fat Body    120.3 Larval Salivary Gland    155.1 Larval Trachea    222.725 Larval Carcass    111.275 Adult Head    166.7 Adult Eye    189.6 Adult Brain    247 Adult Thoracic-Abdominal Ganglion    248.6 Adult Crop    176 Adult Midgut    148.8 Adult Hindgut    204.4 Adult Malpighian Tubules    82 Adult Fat Body    184.6 Adult Salivary Gland    103.1 Adult Heart    207.825 Adult VirginFemale Spermatheca    78.6 Adult InseminatedFemale Spermatheca    85.7 Adult Ovary    338.5 Adult Testis    57.8 Adult Male Accessory Gland    103.1 Adult Carcass    219.9 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    207.025 Larval Midgut    90.9 Larval Hindgut    228 Larval Malpighian Tubules    104.6 Larval Fat Body    120.3 Larval Salivary Gland    155.1 Larval Trachea    222.725 Larval Carcass    111.275 Adult Head    166.7 Adult Eye    189.6 Adult Brain    247 Adult Thoracic-Abdominal Ganglion    248.6 Adult Crop    176 Adult Midgut    148.8 Adult Hindgut    204.4 Adult Malpighian Tubules    82 Adult Fat Body    184.6 Adult Salivary Gland    103.1 Adult Heart    207.825 Adult VirginFemale Spermatheca    78.6 Adult InseminatedFemale Spermatheca    85.7 Adult Ovary    338.5 Adult Testis    57.8 Adult Male Accessory Gland    103.1 Adult Carcass    219.9 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    207.025 Larval Midgut    90.9 Larval Hindgut    228 Larval Malpighian Tubules    104.6 Larval Fat Body    120.3 Larval Salivary Gland    155.1 Larval Trachea    222.725 Larval Carcass    111.275 Adult Head    166.7 Adult Eye    189.6 Adult Brain    247 Adult Thoracic-Abdominal Ganglion    248.6 Adult Crop    176 Adult Midgut    148.8 Adult Hindgut    204.4 Adult Malpighian Tubules    82 Adult Fat Body    184.6 Adult Salivary Gland    103.1 Adult Heart    207.825 Adult VirginFemale Spermatheca    78.6 Adult InseminatedFemale Spermatheca    85.7 Adult Ovary    338.5 Adult Testis    57.8 Adult Male Accessory Gland    103.1 Adult Carcass    219.9 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    207.025 Larval Midgut    90.9 Larval Hindgut    228 Larval Malpighian Tubules    104.6 Larval Fat Body    120.3 Larval Salivary Gland    155.1 Larval Trachea    222.725 Larval Carcass    111.275 Adult Head    166.7 Adult Eye    189.6 Adult Brain    247 Adult Thoracic-Abdominal Ganglion    248.6 Adult Crop    176 Adult Midgut    148.8 Adult Hindgut    204.4 Adult Malpighian Tubules    82 Adult Fat Body    184.6 Adult Salivary Gland    103.1 Adult Heart    207.825 Adult VirginFemale Spermatheca    78.6 Adult InseminatedFemale Spermatheca    85.7 Adult Ovary    338.5 Adult Testis    57.8 Adult Male Accessory Gland    103.1 Adult Carcass    219.9 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    207.025 Larval Midgut    90.9 Larval Hindgut    228 Larval Malpighian Tubules    104.6 Larval Fat Body    120.3 Larval Salivary Gland    155.1 Larval Trachea    222.725 Larval Carcass    111.275 Adult Head    166.7 Adult Eye    189.6 Adult Brain    247 Adult Thoracic-Abdominal Ganglion    248.6 Adult Crop    176 Adult Midgut    148.8 Adult Hindgut    204.4 Adult Malpighian Tubules    82 Adult Fat Body    184.6 Adult Salivary Gland    103.1 Adult Heart    207.825 Adult VirginFemale Spermatheca    78.6 Adult InseminatedFemale Spermatheca    85.7 Adult Ovary    338.5 Adult Testis    57.8 Adult Male Accessory Gland    103.1 Adult Carcass    219.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    207.025 Larval Midgut    90.9 Larval Hindgut    228 Larval Malpighian Tubules    104.6 Larval Fat Body    120.3 Larval Salivary Gland    155.1 Larval Trachea    222.725 Larval Carcass    111.275 Adult Head    166.7 Adult Eye    189.6 Adult Brain    247 Adult Thoracic-Abdominal Ganglion    248.6 Adult Crop    176 Adult Midgut    148.8 Adult Hindgut    204.4 Adult Malpighian Tubules    82 Adult Fat Body    184.6 Adult Salivary Gland    103.1 Adult Heart    207.825 Adult VirginFemale Spermatheca    78.6 Adult InseminatedFemale Spermatheca    85.7 Adult Ovary    338.5 Adult Testis    57.8 Adult Male Accessory Gland    103.1 Adult Carcass    219.9 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    207.025 Larval Midgut    90.9 Larval Hindgut    228 Larval Malpighian Tubules    104.6 Larval Fat Body    120.3 Larval Salivary Gland    155.1 Larval Trachea    222.725 Larval Carcass    111.275 Adult Head    166.7 Adult Eye    189.6 Adult Brain    247 Adult Thoracic-Abdominal Ganglion    248.6 Adult Crop    176 Adult Midgut    148.8 Adult Hindgut    204.4 Adult Malpighian Tubules    82 Adult Fat Body    184.6 Adult Salivary Gland    103.1 Adult Heart    207.825 Adult VirginFemale Spermatheca    78.6 Adult InseminatedFemale Spermatheca    85.7 Adult Ovary    338.5 Adult Testis    57.8 Adult Male Accessory Gland    103.1 Adult Carcass    219.9 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    207.025 Larval Midgut    90.9 Larval Hindgut    228 Larval Malpighian Tubules    104.6 Larval Fat Body    120.3 Larval Salivary Gland    155.1 Larval Trachea    222.725 Larval Carcass    111.275 Adult Head    166.7 Adult Eye    189.6 Adult Brain    247 Adult Thoracic-Abdominal Ganglion    248.6 Adult Crop    176 Adult Midgut    148.8 Adult Hindgut    204.4 Adult Malpighian Tubules    82 Adult Fat Body    184.6 Adult Salivary Gland    103.1 Adult Heart    207.825 Adult VirginFemale Spermatheca    78.6 Adult InseminatedFemale Spermatheca    85.7 Adult Ovary    338.5 Adult Testis    57.8 Adult Male Accessory Gland    103.1 Adult Carcass    219.9 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    166.7   NA  Eye    189.6   NA  Brain    247   207.025  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    248.6   NA  Crop    176   90.9  Midgut    148.8   228  Hindgut    204.4   104.6  Malpighian Tubules    82   120.3  Fat Body    184.6   155.1  Salivary Gland    103.1   NA  Heart    207.825   222.725  Trachea    NA   NA  VirginFemale Spermatheca    78.6   NA  InseminatedFemale Spermatheca    85.7   NA  Ovary    338.5   NA  Testis    57.8   NA  Male Accessory Gland    103.1   111.275  Carcass    219.9 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    9 central nervous system, pupae P8    8 head, virgin 1-day female    9 head, virgin 4-day female    7 head, virgin 20-day female    8 head, mated 1-day female    7 head, mated 4-day female    5 head, mated 20-day female    4 head, mated 1-day male    11 head, mated 4-day male    7 head, mated 20-day male    9 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    6 digestive system, 4-day adult    6 digestive system, 20-day adult    8 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    9 carcass, 1-day adult    7 carcass, 4-day adult    7 carcass, 20-day adult    10 ovary, virgin 4-day female    28 ovary, mated 4-day female    24 testis, mated 4-day male    9 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    9 central nervous system, pupae P8    8 head, virgin 1-day female    9 head, virgin 4-day female    7 head, virgin 20-day female    8 head, mated 1-day female    7 head, mated 4-day female    5 head, mated 20-day female    4 head, mated 1-day male    11 head, mated 4-day male    7 head, mated 20-day male    9 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    6 digestive system, 4-day adult    6 digestive system, 20-day adult    8 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    9 carcass, 1-day adult    7 carcass, 4-day adult    7 carcass, 20-day adult    10 ovary, virgin 4-day female  (28) ovary, mated 4-day female    24 testis, mated 4-day male    9 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    9 central nervous system, pupae P8    8 head, virgin 1-day female    9 head, virgin 4-day female    7 head, virgin 20-day female    8 head, mated 1-day female    7 head, mated 4-day female    5 head, mated 20-day female    4 head, mated 1-day male    11 head, mated 4-day male    7 head, mated 20-day male    9 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    6 digestive system, 4-day adult    6 digestive system, 20-day adult    8 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    9 carcass, 1-day adult    7 carcass, 4-day adult    7 carcass, 20-day adult    10 ovary, virgin 4-day female    28 ovary, mated 4-day female    24 testis, mated 4-day male    9 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    9 central nervous system, pupae P8    8 head, virgin 1-day female    9 head, virgin 4-day female    7 head, virgin 20-day female    8 head, mated 1-day female    7 head, mated 4-day female    5 head, mated 20-day female    4 head, mated 1-day male    11 head, mated 4-day male    7 head, mated 20-day male    9 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    6 digestive system, 4-day adult    6 digestive system, 20-day adult    8 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    9 carcass, 1-day adult    7 carcass, 4-day adult    7 carcass, 20-day adult    10 ovary, virgin 4-day female    28 ovary, mated 4-day female    24 testis, mated 4-day male    9 accessory gland, mated 4-day male    4 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    9 central nervous system, pupae P8    8 head, virgin 1-day female    9 head, virgin 4-day female    7 head, virgin 20-day female    8 head, mated 1-day female    7 head, mated 4-day female    5 head, mated 20-day female    4 head, mated 1-day male    11 head, mated 4-day male    7 head, mated 20-day male    9 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    6 digestive system, 4-day adult    6 digestive system, 20-day adult    8 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    9 carcass, 1-day adult    7 carcass, 4-day adult    7 carcass, 20-day adult    10 ovary, virgin 4-day female    28 ovary, mated 4-day female    24 testis, mated 4-day male    9 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    9 central nervous system, pupae P8    8 head, virgin 1-day female    9 head, virgin 4-day female    7 head, virgin 20-day female    8 head, mated 1-day female    7 head, mated 4-day female    5 head, mated 20-day female    4 head, mated 1-day male    11 head, mated 4-day male    7 head, mated 20-day male    9 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    6 digestive system, 4-day adult    6 digestive system, 20-day adult    8 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    9 carcass, 1-day adult    7 carcass, 4-day adult    7 carcass, 20-day adult    10 ovary, virgin 4-day female  28 ovary, mated 4-day female    24 testis, mated 4-day male    9 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    9 central nervous system, pupae P8    8 head, virgin 1-day female    9 head, virgin 4-day female    7 head, virgin 20-day female    8 head, mated 1-day female    7 head, mated 4-day female    5 head, mated 20-day female    4 head, mated 1-day male    11 head, mated 4-day male    7 head, mated 20-day male    9 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    6 digestive system, 4-day adult    6 digestive system, 20-day adult    8 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    9 carcass, 1-day adult    7 carcass, 4-day adult    7 carcass, 20-day adult    10 ovary, virgin 4-day female    28 ovary, mated 4-day female    24 testis, mated 4-day male    9 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    18 central nervous system, larvae L3    9 central nervous system, pupae P8    8 head, virgin 1-day female    9 head, virgin 4-day female    7 head, virgin 20-day female    8 head, mated 1-day female    7 head, mated 4-day female    5 head, mated 20-day female    4 head, mated 1-day male    11 head, mated 4-day male    7 head, mated 20-day male    9 salivary gland, larvae L3 wandering    1 salivary gland, white prepupae    1 digestive system, larvae L3 wandering    6 digestive system, 1-day adult    6 digestive system, 4-day adult    6 digestive system, 20-day adult    8 fat body, larvae L3 wandering    3 fat body, white prepupae    4 fat body, pupae P8    13 carcass, larvae L3 wandering    9 carcass, 1-day adult    7 carcass, 4-day adult    7 carcass, 20-day adult    10 ovary, virgin 4-day female    28 ovary, mated 4-day female    24 testis, mated 4-day male    9 accessory gland, mated 4-day male    4 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderate expression. Peak expression observed during early larval stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    43 embryo 02-04hr    7 embryo 04-06hr    23 embryo 06-08hr    29 embryo 08-10hr    28 embryo 10-12hr    40 embryo 12-14hr    34 embryo 14-16hr    46 embryo 16-18hr    48 embryo 18-20hr    52 embryo 20-22hr    41 embryo 22-24hr    36 larva L1    52 larva L2    55 larva L3 12hr old    37 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    15 white prepupae new    14 white prepupae 12hr    16 white prepupae 24hr    16 pupae 2d postWPP    33 pupae 3d postWPP    39 pupae 4d postWPP    22 adult male 01day    20 adult male 05day    20 adult male 30day    20 adult female 01day    37 adult female 05day    41 adult female 30day    44 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (43) embryo 02-04hr    7 embryo 04-06hr    23 embryo 06-08hr  (29) embryo 08-10hr  (28) embryo 10-12hr  (40) embryo 12-14hr  (34) embryo 14-16hr  (46) embryo 16-18hr  (48) embryo 18-20hr  (52) embryo 20-22hr  (41) embryo 22-24hr  (36) larva L1  (52) larva L2  (55) larva L3 12hr old  (37) larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    15 white prepupae new    14 white prepupae 12hr    16 white prepupae 24hr    16 pupae 2d postWPP  (33) pupae 3d postWPP  (39) pupae 4d postWPP    22 adult male 01day    20 adult male 05day    20 adult male 30day    20 adult female 01day  (37) adult female 05day  (41) adult female 30day  (44) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    43 embryo 02-04hr    7 embryo 04-06hr    23 embryo 06-08hr    29 embryo 08-10hr    28 embryo 10-12hr    40 embryo 12-14hr    34 embryo 14-16hr    46 embryo 16-18hr    48 embryo 18-20hr    52 embryo 20-22hr    41 embryo 22-24hr    36 larva L1    52 larva L2    55 larva L3 12hr old    37 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    15 white prepupae new    14 white prepupae 12hr    16 white prepupae 24hr    16 pupae 2d postWPP    33 pupae 3d postWPP    39 pupae 4d postWPP    22 adult male 01day    20 adult male 05day    20 adult male 30day    20 adult female 01day    37 adult female 05day    41 adult female 30day    44 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    43 embryo 02-04hr    7 embryo 04-06hr    23 embryo 06-08hr    29 embryo 08-10hr    28 embryo 10-12hr    40 embryo 12-14hr    34 embryo 14-16hr    46 embryo 16-18hr    48 embryo 18-20hr    52 embryo 20-22hr    41 embryo 22-24hr    36 larva L1    52 larva L2    55 larva L3 12hr old    37 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    15 white prepupae new    14 white prepupae 12hr    16 white prepupae 24hr    16 pupae 2d postWPP    33 pupae 3d postWPP    39 pupae 4d postWPP    22 adult male 01day    20 adult male 05day    20 adult male 30day    20 adult female 01day    37 adult female 05day    41 adult female 30day    44 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    43 embryo 02-04hr    7 embryo 04-06hr    23 embryo 06-08hr    29 embryo 08-10hr    28 embryo 10-12hr    40 embryo 12-14hr    34 embryo 14-16hr    46 embryo 16-18hr    48 embryo 18-20hr    52 embryo 20-22hr    41 embryo 22-24hr    36 larva L1    52 larva L2    55 larva L3 12hr old    37 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    15 white prepupae new    14 white prepupae 12hr    16 white prepupae 24hr    16 pupae 2d postWPP    33 pupae 3d postWPP    39 pupae 4d postWPP    22 adult male 01day    20 adult male 05day    20 adult male 30day    20 adult female 01day    37 adult female 05day    41 adult female 30day    44 Expression Level Scale  Very low   Low   Moderate   Moderately high   High  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (43) embryo 02-04hr    7 embryo 04-06hr    23 embryo 06-08hr  29 embryo 08-10hr  28 embryo 10-12hr  (40) embryo 12-14hr  (34) embryo 14-16hr  (46) embryo 16-18hr  (48) embryo 18-20hr  (52) embryo 20-22hr  (41) embryo 22-24hr  (36) larva L1  (52) larva L2  (55) larva L3 12hr old  (37) larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    15 white prepupae new    14 white prepupae 12hr    16 white prepupae 24hr    16 pupae 2d postWPP  (33) pupae 3d postWPP  (39) pupae 4d postWPP    22 adult male 01day    20 adult male 05day    20 adult male 30day    20 adult female 01day  (37) adult female 05day  (41) adult female 30day  (44) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    43 embryo 02-04hr    7 embryo 04-06hr    23 embryo 06-08hr    29 embryo 08-10hr    28 embryo 10-12hr    40 embryo 12-14hr    34 embryo 14-16hr    46 embryo 16-18hr    48 embryo 18-20hr    52 embryo 20-22hr    41 embryo 22-24hr    36 larva L1    52 larva L2    55 larva L3 12hr old    37 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    15 white prepupae new    14 white prepupae 12hr    16 white prepupae 24hr    16 pupae 2d postWPP    33 pupae 3d postWPP    39 pupae 4d postWPP    22 adult male 01day    20 adult male 05day    20 adult male 30day    20 adult female 01day    37 adult female 05day    41 adult female 30day    44 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    43 embryo 02-04hr    7 embryo 04-06hr    23 embryo 06-08hr    29 embryo 08-10hr    28 embryo 10-12hr    40 embryo 12-14hr    34 embryo 14-16hr    46 embryo 16-18hr    48 embryo 18-20hr    52 embryo 20-22hr    41 embryo 22-24hr    36 larva L1    52 larva L2    55 larva L3 12hr old    37 larva L3 puffstage 1-2    15 larva L3 puffstage 3-6    16 larva L3 puffstage 7-9    15 white prepupae new    14 white prepupae 12hr    16 white prepupae 24hr    16 pupae 2d postWPP    33 pupae 3d postWPP    39 pupae 4d postWPP    22 adult male 01day    20 adult male 05day    20 adult male 30day    20 adult female 01day    37 adult female 05day    41 adult female 30day    44 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    27 Schneider line 2 Sg4    23 embryonic 1182-4H    20 embryonic GM2    17 embryonic Kc167    20 embryonic S1    27 embryonic S3    27 leg disc CME L1    21 wing disc CME-W2    13 wing disc ML-DmD8    18 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    10 wing disc ML-DmD21    34 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    21 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    12 tumorous blood cells mbn2    13 ovary fGS/OSS    17 ovary OSC    16 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (27) Schneider line 2 Sg4    23 embryonic 1182-4H    20 embryonic GM2    17 embryonic Kc167    20 embryonic S1  (27) embryonic S3  (27) leg disc CME L1    21 wing disc CME-W2    13 wing disc ML-DmD8    18 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    10 wing disc ML-DmD21  (34) wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11  (29) antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    21 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    12 tumorous blood cells mbn2    13 ovary fGS/OSS    17 ovary OSC    16 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    27 Schneider line 2 Sg4    23 embryonic 1182-4H    20 embryonic GM2    17 embryonic Kc167    20 embryonic S1    27 embryonic S3    27 leg disc CME L1    21 wing disc CME-W2    13 wing disc ML-DmD8    18 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    10 wing disc ML-DmD21    34 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    21 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    12 tumorous blood cells mbn2    13 ovary fGS/OSS    17 ovary OSC    16 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    27 Schneider line 2 Sg4    23 embryonic 1182-4H    20 embryonic GM2    17 embryonic Kc167    20 embryonic S1    27 embryonic S3    27 leg disc CME L1    21 wing disc CME-W2    13 wing disc ML-DmD8    18 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    10 wing disc ML-DmD21    34 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    21 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    12 tumorous blood cells mbn2    13 ovary fGS/OSS    17 ovary OSC    16 ovary OSS    6 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    27 Schneider line 2 Sg4    23 embryonic 1182-4H    20 embryonic GM2    17 embryonic Kc167    20 embryonic S1    27 embryonic S3    27 leg disc CME L1    21 wing disc CME-W2    13 wing disc ML-DmD8    18 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    10 wing disc ML-DmD21    34 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    21 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    12 tumorous blood cells mbn2    13 ovary fGS/OSS    17 ovary OSC    16 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  27 Schneider line 2 Sg4    23 embryonic 1182-4H    20 embryonic GM2    17 embryonic Kc167    20 embryonic S1  27 embryonic S3  27 leg disc CME L1    21 wing disc CME-W2    13 wing disc ML-DmD8    18 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    10 wing disc ML-DmD21  (34) wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11  29 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    21 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    12 tumorous blood cells mbn2    13 ovary fGS/OSS    17 ovary OSC    16 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+    27 Schneider line 2 Sg4    23 embryonic 1182-4H    20 embryonic GM2    17 embryonic Kc167    20 embryonic S1    27 embryonic S3    27 leg disc CME L1    21 wing disc CME-W2    13 wing disc ML-DmD8    18 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    10 wing disc ML-DmD21    34 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    21 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    12 tumorous blood cells mbn2    13 ovary fGS/OSS    17 ovary OSC    16 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    27 Schneider line 2 Sg4    23 embryonic 1182-4H    20 embryonic GM2    17 embryonic Kc167    20 embryonic S1    27 embryonic S3    27 leg disc CME L1    21 wing disc CME-W2    13 wing disc ML-DmD8    18 wing disc ML-DmD9    22 wing disc ML-DmD16-c3    10 wing disc ML-DmD21    34 wing disc ML-DmD32    10 haltere disc ML-DmD17-c3    17 eye-antennal disc ML-DmD11    29 antennal disc ML-DmD20-c5    23 mixed discs ML-DmD4-c1    21 CNS ML-DmBG1-c1    22 CNS ML-DmBG2-c2    12 tumorous blood cells mbn2    13 ovary fGS/OSS    17 ovary OSC    16 ovary OSS    6 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    5 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    14 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    28 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    14 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    5 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    14 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3  (28) Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    14 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    5 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    14 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    28 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    14 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    5 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    14 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    28 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    14 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    5 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    14 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    28 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    14 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    5 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    14 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3  28 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    14 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    5 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    14 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    28 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    14 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    8 cold shock, 4-day adult    5 heat shock, 4-day adult    14 Cadmium 50 mM 6 hrs, larvae L3    14 Cadmium 50 mM 12 hrs, larvae L3    8 Cadmium 50 mM 48 hrs, 4-day adult    10 Cadmium 100 mM 48 hrs, 4-day adult    16 Copper 0.5 mM 12 hrs, larvae L3    7 Copper 15 mM 48 hrs, 4-day adult    7 Zinc 5 mM 12 hrs, larvae L3    4 Zinc 4.5 mM 48 hrs, 4-day adult    3 Ethanol 2.5% 3 hrs, larvae L3    28 Ethanol 5% 3 hrs, larvae L3    13 Ethanol 10% 3 hrs, larvae L3    14 Caffeine 1.5 mg/ml 4 hrs, larvae L3    11 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    15 Caffeine 25 mg/ml 48 hrs, 4-day adult    3 Paraquat 5 mM 48 hrs, 4-day adult    18 Paraquat 10 mM 48 hrs, 4-day adult    23 Rotenone 2 μg 12 hrs, larvae L3    15 Rotenone 8 μg 12 hrs, larvae L3    18 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_19 mE1_20_mRNA_expression_cluster_03
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030552 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG15871-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 mRpL38GD9136 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 mRpL38GD9136 Phenotype manifest in Allele trichogen cell, with Scer\GAL4pnr-MD237 mRpL38GD9136
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of mRpL38 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of mRpL38 Class Mutagen Stocks Known lesion mRpL38GD9136 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes mRpL38NIG.15871R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD9136} NA P{NIG.15871R} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 4 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
phosphatidylethanolamine binding inferred from sequence or structural similarity with EMBL:AF016423 (FlyBase, 1992-) structural constituent of ribosome inferred from sequence or structural similarity with EMBL:AI074410 (Suzuki et al., 2001)
Biological Process
CV term Evidence References
translation inferred from sequence or structural similarity with EMBL:AI074410 (Suzuki et al., 2001)
Cellular Component
CV term Evidence References
mitochondrial large ribosomal subunit inferred from sequence or structural similarity with EMBL:AI074410 (Suzuki et al., 2001)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
mRpL38 - CG1340 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL38 - CG7766 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL38 - Hex-A anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL38 - dbe anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) mRpL38 - mRpL23 experimental knowledge based (Guruharsha et al., 2011) mRpL38 - mRpL30 experimental knowledge based (Guruharsha et al., 2011) mRpL38 - mRpL47 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions mRpL38 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 58742 DroID - A comprehensive database of gene and protein interactions. • FBgn0030552 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32375
Orthologs
OrthoDB Orthologs (39) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6DV662 Dipteran inclusive ortholog search EOG6R50B8 Insect inclusive ortholog search EOG69ZWK6 Arthropod inclusive ortholog search EOG6FFBHR Metazoa inclusive ortholog search EOG6BCSG3
Orthologs in Drosophila Species (EOG6DV662)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\mRpL38     Drosophila simulans   Dsim\GD17162 Y   Drosophila sechellia   Dsec\GM17664 Y   Drosophila erecta   Dere\GG17835 Y   Drosophila yakuba   Dyak\GE17128 Y   Drosophila ananassae   Dana\GF15958 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA13994 Y   Drosophila persimilis   Dper\GL12995 Y   Drosophila persimilis   Dper\GL19977     Drosophila willistoni   Dwil\GK25755 Y   Drosophila virilis   Dvir\GJ19158 Y   Drosophila mojavensis   Dmoj\GI14755 Y   Drosophila grimshawi   Dgri\GH12376 Y
Orthologs in non-Drosophila Dipterans (EOG6R50B8)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL011198   Anopheles gambiae Malaria mosquito  Agam\AGAP000652   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ009811
Orthologs in non-Dipteran Insects (EOG69ZWK6)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\mRpL38   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG007176   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH11351   Atta cephalotes Leafcutter ant  Acep\ACEP16080   Camponotus floridanus Florida carpenter ant  Cflo\CFLO20733   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL21113   Linepithema humile Argentine ant  Lhum\LH19295   Pogonomyrmex barbatus Red harvester ant  Pbar\PB17533   Solenopsis invicta Red fire ant  Sinv\SINV10879   Acyrthosiphon pisum Pea aphid  Apim\ACYPI008716   Bombyx mori Silkmoth  Bmor\BGIBMGA010593   Pediculus humanus Human body louse  Phum\PHUM580880   Tribolium castaneum Red flour beetle  Tcas\TC002530
Orthologs in non-Insect Arthropods (EOG6FFBHR)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\SRSF8   Ixodes scapularis Deer tick  Isca\ISCW021329
Orthologs in non-Arthropod Metazoa (EOG6BCSG3)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\mrpl-38   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_009657gn   Danio rerio Zebrafish  Drer\mrpl38   Xenopus tropicalis Western clawed frog  Xtro\mrpl38   Gallus gallus Domestic chicken  Ggal\MRPL38   Mus musculus House mouse  Mmus\Mrpl38   Rattus norvegicus Norway rat  Rnor\Mrpl38   Homo sapiens Human  Hsap\MRPL38
Human Orthologs (1)
Gene OMIM HGNC Hsap\MRPL38
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD17162 Drosophila sechellia Dsec\GM17664 Drosophila erecta Dere\GG17835 Drosophila yakuba Dyak\GE17128 Drosophila ananassae Dana\GF15958 Drosophila pseudoobscura pseudoobscura Dpse\GA13994 Drosophila persimilis Dper\GL12995 Drosophila willistoni Dwil\GK25755 Drosophila virilis Dvir\GJ19158 Drosophila mojavensis Dmoj\GI14755 Drosophila grimshawi Dgri\GH12376
Stocks & Reagents
Stocks Listed in FlyBase ( 2 )
VDRC	v43691 w1118; P{GD9136}v43691/TM3 v43692 w1118; P{GD9136}v43692/CyO
Genomic Clones ( 1 )
	BACR12J05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 23 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	IP07725 RE63629
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM24925 GM28657 GM30522 LP11117 RE07075 RE07239 RE60912 RE67520 RE70404 RE70775
Other clones	17128 65791 75323 160329 191831 EK018731 EK128733 EK263264 EK294920 EP07707 RH61928
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030552 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32375
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: mRpL3a CG15871 (Suzuki et al., 2001)
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_078597 RefSeq (Proteins) • NP_511152 DDBJ / EMBL / GenBank • AAF48357 AAL49202 AY071580 BI375758 Entrez Gene - A searchable database of RefSeq genes. • 32375 UniProtKB/TrEMBL • Q9VY48
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Phosphatidylethanolamine-binding protein PEBP (IPR008914)
Linkouts
	BioGRID - A database of protein and genetic interactions • 58742 DroID - A comprehensive database of gene and protein interactions. • FBgn0030552 DRSC - Results from RNAi screens. • FBgn0030552 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030552 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG15871-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030552 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32375 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32375 modMine - Data generated by the modENCODE project. • FBgn0030552
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	CG15871 (Marygold et al., 2007, Cammarato et al., 2011) MRP-L3 (Suzuki et al., 2001) mRpL3a   mRpL38 (Marygold et al., 2007, Japanese National Institute of Genetics, 2012.5.21)
Name Synonym	mitochondrial ribosomal protein L3a (Suzuki et al., 2001) mitochondrial ribosomal protein L38 (Marygold, 2004.9.8, Cammarato et al., 2011)
Secondary FlyBase IDs
References ( 17 )
Research paper	Marygold et al., 2007, Genome Biol. 8(10): R216 The ribosomal protein genes and Minute loci of Drosophila melanogaster. [FBrf0205398] Suzuki et al., 2001, J. Biol. Chem. 276(24): 21724--21736 Structural compensation for the deficit of rRNA with proteins in the mammalian mitochondrial ribosome. Systematic analysis of protein components of the large ribosomal subunit from mammalian mitochondria. [FBrf0136752]
Supplementary material	Cammarato et al., 2011, PLoS ONE 6(4): Table S1. Proteins & Peptides. [FBrf0214682] Graveley et al., 2011, Nature 471(7339): Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980] Guruharsha et al., 2011, Cell 147(3): Table S3. [FBrf0218395] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Marygold, 2004.9.8, Ribosomal protein nomenclature in D.melanogaster. Ribosomal protein nomenclature in D.melanogaster. [FBrf0179760] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file) Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078]
FlyBase analysis	FlyBase, 1992-, FlyBase curation. FlyBase curation. [FBrf0105495]
Stock list	Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY. RNAi stocks available from NIG-FLY. [FBrf0218457]
Curated genome annotation	FamiliarityBreedsContempt, 1999.11, [Automatic annotations performed at the Celera Jamboreee.] [Automatic annotations performed at the Celera Jamboreee.] [FBrf0126705] Milshina, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126686]