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Gene Dmel\CG5334

General Information
Symbol	Dmel\CG5334	Species	D. melanogaster
Name		Annotation symbol	CG5334
Feature type	protein_coding_gene	FlyBase ID	FBgn0030577
Gene Model Status	Current	Stock availability	1 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	12F4-12F4	Sequence location	X:14,669,392..14,670,151 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG5334 (FBgn0030577). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding; nucleic acid binding. The biological processes in which it is involved are not known. 2 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: Zinc finger, C3HC4 RING-type; Zinc finger, CCCH-type; Zinc finger, RING-type; Zinc finger, RING-type, conserved site; Zinc finger, RING/FYVE/PHD-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderate expression to a trough of no expression detected. Peak expression observed in adult male stages. Summary of FlyAtlas Anatomical Expression Data: Little or no expression detected in any larval or adult organs/tissues. Comments on Affy2 ProbeSet: ProbeSet 1636725_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG5334. Gene sequence location is X:14669392..14670151.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features HFA19941 BKN32373
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 12F4-12F4   Limits computationally determined from genome sequence between P{EP}EP1599 and P{EP}EP334&P{EP}EP977
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG5334 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG5334-RA FBtr0073935  NM_132741   760   210
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG5334-PA   FBpp0073752   24.4   210   8.59     NP_572969   AAF48384
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, CCCH-type (IPR000571) Zinc finger, RING-type (IPR001841) Zinc finger, RING-type, conserved site (IPR017907) Zinc finger, C3HC4 RING-type (IPR018957) Zinc finger, RING/FYVE/PHD-type (IPR013083)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AE014298 AAF48384
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VY21
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. [an error occurred while processing this directive] modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030577 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5334-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Phenotype manifest in Allele
Classical Alleles ( 0 )
For All Classical Alleles Show
Allele of CG5334 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs ( 2 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG5334 Class Mutagen Stocks Known lesion CG5334KK112373 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG5334GD10727 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD10727} NA P{KK112373} NA
Insertions
	Type of insertions Name Expression data
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
nucleic acid binding inferred from electronic annotation with InterPro:IPR000571 (FlyBase Curators et al., 2004-) zinc ion binding inferred from electronic annotation with InterPro:IPR000571, InterPro:IPR001841 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG5334 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 58763 DroID - A comprehensive database of gene and protein interactions. • FBgn0030577 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32402
Orthologs
Genome-wide drosophilid orthologs	Dsec\GM12044 Dsim\GD17178
Curated drosophilid orthologs
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • ENSGACP00000010952 Gymnopilus aculeatus (mushroom) ENSGALP00000034421 Gallus gallus (chicken) ENSORLP00000008302 Oryzias latipes (japanese killifish) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0166985
Stocks & Reagents
Stocks Listed in FlyBase ( 1 )
VDRC	v102765 P{KK112373}VIE-260B
Genomic Clones ( 1 )
	BACR08K05 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 0 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones
Other clones
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030577 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32402
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132741 RefSeq (Proteins) • NP_572969 DDBJ / EMBL / GenBank • AAF48384 Entrez Gene - A searchable database of RefSeq genes. • 32402 UniProtKB/TrEMBL • Q9VY21
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Zinc finger, CCCH-type (IPR000571) Zinc finger, RING-type (IPR001841) Zinc finger, RING-type, conserved site (IPR017907) Zinc finger, C3HC4 RING-type (IPR018957) Zinc finger, RING/FYVE/PHD-type (IPR013083)
Linkouts
	BioGRID - A database of protein and genetic interactions • 58763 DroID - A comprehensive database of gene and protein interactions. • FBgn0030577 DRSC - Results from RNAi screens. • FBgn0030577 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030577 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5334-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030577 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32402 InParanoid A subset of ortholog calls from InParanoid. • ENSGACP00000010952 Gymnopilus aculeatus (mushroom) ENSGALP00000034421 Gallus gallus (chicken) ENSORLP00000008302 Oryzias latipes (japanese killifish) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32402 modMine - Data generated by the modENCODE project. • FBgn0030577 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0166985
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG5334 (Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 5 )
Supplementary material	Dietzl et al., 2007, Nature 448(7150): Supplementary Table 1. [FBrf0202579] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]