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Gene Dmel\CG5541

General Information
Symbol	Dmel\CG5541	Species	D. melanogaster
Name		Annotation symbol	CG5541
Feature type	protein_coding_gene	FlyBase ID	FBgn0030603
Gene Model Status	Current	Stock availability	3 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	13A5-13A5	Sequence location	X:14,938,141..14,945,533 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG5541 (FBgn0030603). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: C-type lectin, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval midgut, larval Malpighian tubules, adult heart, adult salivary gland, virgin spermatheca. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, adult crop, adult midgut, larval/adult hindgut, adult Malpighian tubules, adult fat body, larval salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1640963_at partially aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG5541: 10 out of 14 probes fall into this exonic region. Gene sequence location is X:14938141..14945533.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10
FB2012_01	Sequence features HFA19946 BKN45827 BKN24328
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 13A5-13A5   Limits computationally determined from genome sequence between P{EP}hiwEP1305 and P{EP}hiwEP1308
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG5541 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	May be component of a dicistronic gene; available data inconclusive
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG5541-RA FBtr0073958  NM_206715   2187   463 CG5541-RB FBtr0073959  NM_206714   3394   463
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG5541-PA   FBpp0073775   52.9   463   7.53     NP_996438   AAF48414 CG5541-PB   FBpp0073776   52.9   463   7.53     NP_996437   AAN09350
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • C-type lectin, conserved site (IPR018378)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA201600   AA263971   AA264574   AA439899   AA440671   AA440698   AA440718   AA540796   AA816801   AE014298 AAF48414   AE014298 AAN09350   AI456721   AI456963   AI516641   AI531665   AW944269   AY084203 AAL89941   AY119657   BG638823   BI162128   BI168275   BI231864   BI234226   BI236169   BI238643   BI357418   BI368273   BI372839   BI374089   BI484445   BI487234   BI577184   BI578807   BI639136   BI641077   BP540550   BP540551   BP542675   BP543085   BP543086   BP545908   BT016012   BT044236   BT125729   CO279220   CO292534   CO306172   CO310828   CO339061   EC061240   EC073391   EC080161   EC088876   EC194493   EC198791   EC213497   EC215542   EC233503   EC254253   EV577016   EV583300   GH749168   GH749415   GH749608   GH751982   GH752195   GH752686   GH752968   GH755178   GH755195   GH755956   GH771534   GH772149   GH773403   GH773526   GH773646   GH775759   GH779891   GH781449   GH781749   GH782769   GH783267   GH783327   GH784669   GH786602   GH788629   GH790712   GH791100   GH791131   GH791426   GH793137   GH793535   GH793767   GH797103   GH797865   GH798737   GH798985   GH799409   GH799700   GH800837   GH802913   GH805910   GH809188   GH814274   GH814712   GH815415   GH816691   GH817931   GH818624   GH818954   GH819669   GH819858   GH822418   GH825855   GH825997   GH826108   GH827034   GH827348   GH827657   GH827790   GH827891   GH827985   GH829383   GH829462   GH829885   GH829897   GH830156   GH834956   GH836112   GH836601   GH836768   GH836921   GH837582   GH839225   GH840393   GH840877   GH842661   GH843937   GH846069   GH846664   GH846810   GH849286   GH856247   GH861547   GH862664   GH865251   GH866079   GH866196   GH866381   GH867722   GH869721   GH870178   GH870484   GH872030   GH872141   GH872463   GH872795   GH873086   GH873977   GH874469   GH875617   GH877885   GH878729   GH878893   GH879081   GH879671   GH880101   GH881118   GH881532   GH886441   GH888946   GH891341   GH892930   GH894546   GH895467   GH896432   GH897169   GH897817   GH897963   GH897978   GH898314   GH898428   GH898530   GH898550   GH898724   GH901873   GH902143   GH905786   GH907477   GH908422   GH910167   GH910803   GH915266   GH916017   GH916399   GH917692   GH920239   GH921016   GH921854   GH929772   GH930797   GH933782   GH935346   GH935695   GH937210   GH937662   GH942313
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VXZ2
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0030603    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0030603 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of moderate expression. Peak expression observed at stages throughout embryogenesis, during late larval stages, during early pupal stages, in stages of adults of both sexes. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0030603 expression level Developmental Stage   Expression Level embryo 00-02hr    3469 embryo 02-04hr    3615 embryo 04-06hr    833 embryo 06-08hr    736 embryo 08-10hr    1264 embryo 10-12hr    2021 embryo 12-14hr    1847 embryo 14-16hr    2565 embryo 16-18hr    2890 embryo 18-20hr    2199 embryo 20-22hr    2553 embryo 22-24hr    2574 larva L1    1302 larva L2    1131 larva L3 12hr old    1358 larva L3 puffstage 1-2    1647 larva L3 puffstage 3-6    1375 larva L3 puffstage 7-9    1401 white prepupae new    1935 white prepupae 12hr    1377 white prepupae 24hr    708 pupae 2d postWPP    693 pupae 3d postWPP    655 pupae 4d postWPP    916 adult male 01day    1104 adult male 05day    1263 adult male 30day    1417 adult female 01day    1904 adult female 05day    2349 adult female 30day    2498 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3469) embryo 02-04hr  (3615) embryo 04-06hr  (833) embryo 06-08hr  (736) embryo 08-10hr  (1264) embryo 10-12hr  (2021) embryo 12-14hr  (1847) embryo 14-16hr  (2565) embryo 16-18hr  (2890) embryo 18-20hr  (2199) embryo 20-22hr  (2553) embryo 22-24hr  (2574) larva L1  (1302) larva L2  (1131) larva L3 12hr old  (1358) larva L3 puffstage 1-2  (1647) larva L3 puffstage 3-6  (1375) larva L3 puffstage 7-9  (1401) white prepupae new  (1935) white prepupae 12hr  (1377) white prepupae 24hr  (708) pupae 2d postWPP  (693) pupae 3d postWPP  (655) pupae 4d postWPP  (916) adult male 01day  (1104) adult male 05day  (1263) adult male 30day  (1417) adult female 01day  (1904) adult female 05day  (2349) adult female 30day  (2498) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3469) embryo 02-04hr  (3615) embryo 04-06hr    833 embryo 06-08hr    736 embryo 08-10hr    1264 embryo 10-12hr  (2021) embryo 12-14hr  (1847) embryo 14-16hr  (2565) embryo 16-18hr  (2890) embryo 18-20hr  (2199) embryo 20-22hr  (2553) embryo 22-24hr  (2574) larva L1    1302 larva L2    1131 larva L3 12hr old    1358 larva L3 puffstage 1-2  (1647) larva L3 puffstage 3-6    1375 larva L3 puffstage 7-9  1401 white prepupae new  (1935) white prepupae 12hr    1377 white prepupae 24hr    708 pupae 2d postWPP    693 pupae 3d postWPP    655 pupae 4d postWPP    916 adult male 01day    1104 adult male 05day    1263 adult male 30day  1417 adult female 01day  (1904) adult female 05day  (2349) adult female 30day  (2498) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3469 embryo 02-04hr    3615 embryo 04-06hr    833 embryo 06-08hr    736 embryo 08-10hr    1264 embryo 10-12hr    2021 embryo 12-14hr    1847 embryo 14-16hr    2565 embryo 16-18hr    2890 embryo 18-20hr    2199 embryo 20-22hr    2553 embryo 22-24hr    2574 larva L1    1302 larva L2    1131 larva L3 12hr old    1358 larva L3 puffstage 1-2    1647 larva L3 puffstage 3-6    1375 larva L3 puffstage 7-9    1401 white prepupae new    1935 white prepupae 12hr    1377 white prepupae 24hr    708 pupae 2d postWPP    693 pupae 3d postWPP    655 pupae 4d postWPP    916 adult male 01day    1104 adult male 05day    1263 adult male 30day    1417 adult female 01day    1904 adult female 05day    2349 adult female 30day    2498 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3469 embryo 02-04hr    3615 embryo 04-06hr    833 embryo 06-08hr    736 embryo 08-10hr    1264 embryo 10-12hr    2021 embryo 12-14hr    1847 embryo 14-16hr    2565 embryo 16-18hr    2890 embryo 18-20hr    2199 embryo 20-22hr    2553 embryo 22-24hr    2574 larva L1    1302 larva L2    1131 larva L3 12hr old    1358 larva L3 puffstage 1-2    1647 larva L3 puffstage 3-6    1375 larva L3 puffstage 7-9    1401 white prepupae new    1935 white prepupae 12hr    1377 white prepupae 24hr    708 pupae 2d postWPP    693 pupae 3d postWPP    655 pupae 4d postWPP    916 adult male 01day    1104 adult male 05day    1263 adult male 30day    1417 adult female 01day    1904 adult female 05day    2349 adult female 30day    2498 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0030603 expression level Developmental Stage   Expression Level embryo 00-02hr    3469 embryo 02-04hr    3615 embryo 04-06hr    833 embryo 06-08hr    736 embryo 08-10hr    1264 embryo 10-12hr    2021 embryo 12-14hr    1847 embryo 14-16hr    2565 embryo 16-18hr    2890 embryo 18-20hr    2199 embryo 20-22hr    2553 embryo 22-24hr    2574 larva L1    1302 larva L2    1131 larva L3 12hr old    1358 larva L3 puffstage 1-2    1647 larva L3 puffstage 3-6    1375 larva L3 puffstage 7-9    1401 white prepupae new    1935 white prepupae 12hr    1377 white prepupae 24hr    708 pupae 2d postWPP    693 pupae 3d postWPP    655 pupae 4d postWPP    916 adult male 01day    1104 adult male 05day    1263 adult male 30day    1417 adult female 01day    1904 adult female 05day    2349 adult female 30day    2498 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3469) embryo 02-04hr  (3615) embryo 04-06hr  (833) embryo 06-08hr  (736) embryo 08-10hr  (1264) embryo 10-12hr  (2021) embryo 12-14hr  (1847) embryo 14-16hr  (2565) embryo 16-18hr  (2890) embryo 18-20hr  (2199) embryo 20-22hr  (2553) embryo 22-24hr  (2574) larva L1  (1302) larva L2  (1131) larva L3 12hr old  (1358) larva L3 puffstage 1-2  (1647) larva L3 puffstage 3-6  (1375) larva L3 puffstage 7-9  (1401) white prepupae new  (1935) white prepupae 12hr  (1377) white prepupae 24hr  (708) pupae 2d postWPP  (693) pupae 3d postWPP  (655) pupae 4d postWPP  (916) adult male 01day  (1104) adult male 05day  (1263) adult male 30day  (1417) adult female 01day  (1904) adult female 05day  (2349) adult female 30day  (2498) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3469) embryo 02-04hr  (3615) embryo 04-06hr    833 embryo 06-08hr    736 embryo 08-10hr    1264 embryo 10-12hr  2021 embryo 12-14hr  1847 embryo 14-16hr  (2565) embryo 16-18hr  (2890) embryo 18-20hr  2199 embryo 20-22hr  (2553) embryo 22-24hr  (2574) larva L1    1302 larva L2    1131 larva L3 12hr old    1358 larva L3 puffstage 1-2  1647 larva L3 puffstage 3-6    1375 larva L3 puffstage 7-9  1401 white prepupae new  1935 white prepupae 12hr    1377 white prepupae 24hr    708 pupae 2d postWPP    693 pupae 3d postWPP    655 pupae 4d postWPP    916 adult male 01day    1104 adult male 05day    1263 adult male 30day  1417 adult female 01day  1904 adult female 05day  2349 adult female 30day  (2498) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3469 embryo 02-04hr    3615 embryo 04-06hr    833 embryo 06-08hr    736 embryo 08-10hr    1264 embryo 10-12hr    2021 embryo 12-14hr    1847 embryo 14-16hr    2565 embryo 16-18hr    2890 embryo 18-20hr    2199 embryo 20-22hr    2553 embryo 22-24hr    2574 larva L1    1302 larva L2    1131 larva L3 12hr old    1358 larva L3 puffstage 1-2    1647 larva L3 puffstage 3-6    1375 larva L3 puffstage 7-9    1401 white prepupae new    1935 white prepupae 12hr    1377 white prepupae 24hr    708 pupae 2d postWPP    693 pupae 3d postWPP    655 pupae 4d postWPP    916 adult male 01day    1104 adult male 05day    1263 adult male 30day    1417 adult female 01day    1904 adult female 05day    2349 adult female 30day    2498 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3469 embryo 02-04hr    3615 embryo 04-06hr    833 embryo 06-08hr    736 embryo 08-10hr    1264 embryo 10-12hr    2021 embryo 12-14hr    1847 embryo 14-16hr    2565 embryo 16-18hr    2890 embryo 18-20hr    2199 embryo 20-22hr    2553 embryo 22-24hr    2574 larva L1    1302 larva L2    1131 larva L3 12hr old    1358 larva L3 puffstage 1-2    1647 larva L3 puffstage 3-6    1375 larva L3 puffstage 7-9    1401 white prepupae new    1935 white prepupae 12hr    1377 white prepupae 24hr    708 pupae 2d postWPP    693 pupae 3d postWPP    655 pupae 4d postWPP    916 adult male 01day    1104 adult male 05day    1263 adult male 30day    1417 adult female 01day    1904 adult female 05day    2349 adult female 30day    2498 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0030603    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0030603 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Many larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval midgut, larval Malpighian tubules, adult heart, adult salivary gland, virgin spermatheca. Expression at moderate levels in the following post-embryonic organs or tissues: adult eye, adult crop, adult midgut, larval/adult hindgut, adult Malpighian tubules, adult fat body, larval salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval/adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0030603 expression level Tissue   Expression Level Larval Central Nervous System    63.775 Larval Midgut    763.7 Larval Hindgut    453.2 Larval Malpighian Tubules    607 Larval Fat Body    38.6 Larval Salivary Gland    349.3 Larval Trachea    101.725 Larval Carcass    242.675 Adult Head    76.5 Adult Eye    128.375 Adult Brain    47.4 Adult Thoracic-Abdominal Ganglion    96.6 Adult Crop    350.8 Adult Midgut    183.3 Adult Hindgut    308.7 Adult Malpighian Tubules    154 Adult Fat Body    407.6 Adult Salivary Gland    1057.1 Adult Heart    522.65 Adult VirginFemale Spermatheca    524.6 Adult InseminatedFemale Spermatheca    482 Adult Ovary    243.3 Adult Testis    37.6 Adult Male Accessory Gland    494.9 Adult Carcass    126.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    63.775 Larval Midgut  (763.7) Larval Hindgut    453.2 Larval Malpighian Tubules  (607) Larval Fat Body    38.6 Larval Salivary Gland    349.3 Larval Trachea    101.725 Larval Carcass    242.675 Adult Head    76.5 Adult Eye    128.375 Adult Brain    47.4 Adult Thoracic-Abdominal Ganglion    96.6 Adult Crop    350.8 Adult Midgut    183.3 Adult Hindgut    308.7 Adult Malpighian Tubules    154 Adult Fat Body    407.6 Adult Salivary Gland  (1057.1) Adult Heart  522.65 Adult VirginFemale Spermatheca  524.6 Adult InseminatedFemale Spermatheca    482 Adult Ovary    243.3 Adult Testis    37.6 Adult Male Accessory Gland    494.9 Adult Carcass    126.3 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    63.775 Larval Midgut    763.7 Larval Hindgut    453.2 Larval Malpighian Tubules    607 Larval Fat Body    38.6 Larval Salivary Gland    349.3 Larval Trachea    101.725 Larval Carcass    242.675 Adult Head    76.5 Adult Eye    128.375 Adult Brain    47.4 Adult Thoracic-Abdominal Ganglion    96.6 Adult Crop    350.8 Adult Midgut    183.3 Adult Hindgut    308.7 Adult Malpighian Tubules    154 Adult Fat Body    407.6 Adult Salivary Gland  1057.1 Adult Heart    522.65 Adult VirginFemale Spermatheca    524.6 Adult InseminatedFemale Spermatheca    482 Adult Ovary    243.3 Adult Testis    37.6 Adult Male Accessory Gland    494.9 Adult Carcass    126.3 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    63.775 Larval Midgut    763.7 Larval Hindgut    453.2 Larval Malpighian Tubules    607 Larval Fat Body    38.6 Larval Salivary Gland    349.3 Larval Trachea    101.725 Larval Carcass    242.675 Adult Head    76.5 Adult Eye    128.375 Adult Brain    47.4 Adult Thoracic-Abdominal Ganglion    96.6 Adult Crop    350.8 Adult Midgut    183.3 Adult Hindgut    308.7 Adult Malpighian Tubules    154 Adult Fat Body    407.6 Adult Salivary Gland    1057.1 Adult Heart    522.65 Adult VirginFemale Spermatheca    524.6 Adult InseminatedFemale Spermatheca    482 Adult Ovary    243.3 Adult Testis    37.6 Adult Male Accessory Gland    494.9 Adult Carcass    126.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0030603 expression level Tissue   Expression Level Larval Central Nervous System    63.775 Larval Midgut    763.7 Larval Hindgut    453.2 Larval Malpighian Tubules    607 Larval Fat Body    38.6 Larval Salivary Gland    349.3 Larval Trachea    101.725 Larval Carcass    242.675 Adult Head    76.5 Adult Eye    128.375 Adult Brain    47.4 Adult Thoracic-Abdominal Ganglion    96.6 Adult Crop    350.8 Adult Midgut    183.3 Adult Hindgut    308.7 Adult Malpighian Tubules    154 Adult Fat Body    407.6 Adult Salivary Gland    1057.1 Adult Heart    522.65 Adult VirginFemale Spermatheca    524.6 Adult InseminatedFemale Spermatheca    482 Adult Ovary    243.3 Adult Testis    37.6 Adult Male Accessory Gland    494.9 Adult Carcass    126.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    63.775 Larval Midgut  763.7 Larval Hindgut    453.2 Larval Malpighian Tubules  607 Larval Fat Body    38.6 Larval Salivary Gland    349.3 Larval Trachea    101.725 Larval Carcass    242.675 Adult Head    76.5 Adult Eye    128.375 Adult Brain    47.4 Adult Thoracic-Abdominal Ganglion    96.6 Adult Crop    350.8 Adult Midgut    183.3 Adult Hindgut    308.7 Adult Malpighian Tubules    154 Adult Fat Body    407.6 Adult Salivary Gland  (1057.1) Adult Heart  522.65 Adult VirginFemale Spermatheca  524.6 Adult InseminatedFemale Spermatheca    482 Adult Ovary    243.3 Adult Testis    37.6 Adult Male Accessory Gland    494.9 Adult Carcass    126.3 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    63.775 Larval Midgut    763.7 Larval Hindgut    453.2 Larval Malpighian Tubules    607 Larval Fat Body    38.6 Larval Salivary Gland    349.3 Larval Trachea    101.725 Larval Carcass    242.675 Adult Head    76.5 Adult Eye    128.375 Adult Brain    47.4 Adult Thoracic-Abdominal Ganglion    96.6 Adult Crop    350.8 Adult Midgut    183.3 Adult Hindgut    308.7 Adult Malpighian Tubules    154 Adult Fat Body    407.6 Adult Salivary Gland  1057.1 Adult Heart    522.65 Adult VirginFemale Spermatheca    524.6 Adult InseminatedFemale Spermatheca    482 Adult Ovary    243.3 Adult Testis    37.6 Adult Male Accessory Gland    494.9 Adult Carcass    126.3 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    63.775 Larval Midgut    763.7 Larval Hindgut    453.2 Larval Malpighian Tubules    607 Larval Fat Body    38.6 Larval Salivary Gland    349.3 Larval Trachea    101.725 Larval Carcass    242.675 Adult Head    76.5 Adult Eye    128.375 Adult Brain    47.4 Adult Thoracic-Abdominal Ganglion    96.6 Adult Crop    350.8 Adult Midgut    183.3 Adult Hindgut    308.7 Adult Malpighian Tubules    154 Adult Fat Body    407.6 Adult Salivary Gland    1057.1 Adult Heart    522.65 Adult VirginFemale Spermatheca    524.6 Adult InseminatedFemale Spermatheca    482 Adult Ovary    243.3 Adult Testis    37.6 Adult Male Accessory Gland    494.9 Adult Carcass    126.3 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    76.5   NA  Eye    128.375   NA  Brain    47.4   63.775  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    96.6   NA  Crop    350.8   763.7  Midgut    183.3   453.2  Hindgut    308.7   607  Malpighian Tubules    154   38.6  Fat Body    407.6   349.3  Salivary Gland    1057.1   NA  Heart    522.65   101.725  Trachea    NA   NA  VirginFemale Spermatheca    524.6   NA  InseminatedFemale Spermatheca    482   NA  Ovary    243.3   NA  Testis    37.6   NA  Male Accessory Gland    494.9   242.675  Carcass    126.3 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_09
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030603 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • SD04373 FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for CG5541 Stages(s) 1-3 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 13-16
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele semi-lethal | pupal stage, with Scer\GAL4pnr-MD237 CG5541GD3365 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 CG5541GD3365 Phenotype manifest in Allele mesothoracic tergum, with Scer\GAL4pnr-MD237 CG5541GD3365 trichogen cell, with Scer\GAL4pnr-MD237 CG5541GD3365
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG5541 Class Mutagen Stocks Known lesion CG5541MB02880 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG5541 Class Mutagen Stocks Known lesion CG5541HM05228 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG5541KK105192 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG5541GD3365 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD3365} NA P{KK105192} NA P{TRiP.HM05228} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap binary system Mi{ET1}hiwMB02880 No
Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )
	There is no information supporting a biological process or cellular component term for this gene. (Based on a review of available data before: 2006)
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 0 terms )
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG5541 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030603 DroID - A comprehensive database of gene and protein interactions. • FBgn0030603
Orthologs
Genome-wide drosophilid orthologs	Dana\GF22075 Dere\GG17857 Dgri\GH12763 Dmoj\GI15208 Dper\GL26781 Dpse\GA23054 Dsec\GM12052 Dsim\GD17186 Dvir\GJ16618 Dwil\GK20122 Dyak\GE17160
Curated drosophilid orthologs
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL004070-PA Aedes aegypti (mosquito) XP_001947132.1 Acyrthosiphon pisum (pea aphid) BGIBMGA012249-PA Bombyx mori (silk worm) CPIJ003143 Culex pipens (mosquito) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • LH21410 ISCW005178 FBgn0234640 FBgn0222119 FBgn0203802 FBgn0188752 FBgn0166993 JGI_V11_252029 FBgn0244456 FBgn0164362 FBgn0137957 FBgn0120242 FBgn0110077 FBgn0099074 CPIJ003143 BGIBMGA012249 ACYPI009178 GB18582 AAEL004070 PB21212 PHUM483640 GLEAN_03243 GLEAN_00097
Stocks & Reagents
Stocks Listed in FlyBase ( 3 )
Bloomington	30486 y1 sc* v1; P{TRiP.HM05228}attP2 23830 w1118 Mi{ET1}hiwMB02880 CG5541MB02880
VDRC	v106909 P{KK105192}VIE-260B
Genomic Clones ( 1 )
	BACR10J19 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 201 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	RE23381 SD02894 SD04373
Other clones	DPiM_SD02894 FI05801 RT10374
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LD04679 LD06573 LD08265 LD10384 LD14582 LD15530 LD15562 LD15585 LD20614 LD36837 LD37145 LD42572 RE01534 RE08876 RE24810 RE29892 RE32186 RE35148 RE43902 RE54219 RE60024 RE61607 RE67548 RE70756 RE70834 RE72736 SD21590 SD24194
Other clones	19398 19970 34949 42049 100298 147196 165297 214469.28 CK01.6D.D5 CK01.14C.B8 Dmel_dig_002614_0653_0831 Dmel_dig_018636_0650_1294 EK133822 EK200409 EK222744 EK250426 EP00715 FGA005E08 FGC015F07 FGC018E10 FGH001G10 RP003021094 RP003045895 RP003048055 RP003056579 RP003057480 RP003058066 RP003058342 RP003066881 RP003090630 RP003102237 RP003103050 RP003109476 RP003110674 RP003126337 RP003128079 RP003135235 RP003138729 RP003139859 RP003150059 RP003150171 RP003150768 RP003154040 RP003157013 RP003164935 RP003165912 RP003166719 RP003171153 RP003177366 RP003179021 RP003188717 RP003196581 RP003200228 RP003207059 RP003207923 RP003211632 RP003213186 RP003215142 RP003215741 RP003216239 RP003216938 RP003217050 RP003223046 RP003224967 RP003228990 RP003231654 RP003249833 RP003250231 RP003250587 RP003256926 RP003258875 RP003260443 RP003269253 RP003283238 RP003288751 RP003292346 RP003292388 RP003294944 RP003297242 RP003297776 RP003298895 RP003303941 RP003304125 RP003304792 RP003305281 RP003306767 RP003307800 RP003308745 RP003311475 RP003313396 RP003318667 RP003321176 RP003322664 RP003326201 RP003328795 RP003329181 RP003329981 RP003330112 RP003337252 RP003339586 RP003340527 RP003342941 RP003344780 RP003346421 RP003353675 RP003357994 RP003358840 RP003381661 RP003388066 RP003391238 RP003397571 RP003404978 RP003409147 RP003417245 RP003420669 RP003425805 RP003431066 RP003445219 RP003451412 RP003461130 RP003467542 RP003470353 RP003470407 RP003470535 RP003479894 RP003480291 RP003488732 RP003504036 RP003504097 RP003505447 RP003513500 RP003518050 RP003528300 RP003533808 RP003535004 RP003540428 RP003543710 RP003543807 RP003552093 RP003556382 RP003558251 RP003563898 RP003565479 RP003567278 RP003570445 RP003577800 RP003582120 RP003584055 RP003599237 RP003603789 RP003604417 RP003606803 RP003616179 RP003617400 RP003618619 RP003624391 RP003625367 RP003634413 RP003635092 RP003637924 RP003641788 RP003644919 RP003658746 RP003659197 RP003667640 RP003672070 RP003674584
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030603 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 2768877
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG15026 CG5530 CG5541 (FlyBase Genome Annotators, 2002-2003)
Additional comments	Annotation CG5541 split out from annotation CG32594 into a distinct annotation in release 3.2 of the genome annotation. (FlyBase Genome Annotators, 2004) Annotations CG15026, CG5530 and CG5541 merged as CG32594 in release 3 of the genome annotation. (FlyBase Genome Annotators, 2002-2003)
Other Comments
	Expression is enriched in embryonic gonads. (Shigenobu et al., 2006)
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_206714 NM_206715 RefSeq (Proteins) • NP_996437 NP_996438 DDBJ / EMBL / GenBank • AAF48414 AAL89941 AAN09350 AI531665 AW944269 AY084203 Entrez Gene - A searchable database of RefSeq genes. • 2768877 UniProtKB/TrEMBL • Q9VXZ2
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • C-type lectin, conserved site (IPR018378)
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030603 DroID - A comprehensive database of gene and protein interactions. • FBgn0030603 DRSC - Results from RNAi screens. • FBgn0030603 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030603 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • SD04373 FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030603 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 2768877 InParanoid A subset of ortholog calls from InParanoid. • AAEL004070-PA Aedes aegypti (mosquito) XP_001947132.1 Acyrthosiphon pisum (pea aphid) BGIBMGA012249-PA Bombyx mori (silk worm) CPIJ003143 Culex pipens (mosquito) modMine - Data generated by the modENCODE project. • FBgn0030603 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • LH21410 ISCW005178 FBgn0234640 FBgn0222119 FBgn0203802 FBgn0188752 FBgn0166993 JGI_V11_252029 FBgn0244456 FBgn0164362 FBgn0137957 FBgn0120242 FBgn0110077 FBgn0099074 CPIJ003143 BGIBMGA012249 ACYPI009178 GB18582 AAEL004070 PB21212 PHUM483640 GLEAN_03243 GLEAN_00097
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG5541 (Shigenobu et al., 2006, Perkins et al., 2009, Wu et al., 2005, Zhao et al., 2009, Lipatov et al., 2005, Keleman et al., 2009.8.5)
Name Synonym
Secondary FlyBase IDs
References ( 16 )
Research paper	Zhao et al., 2009, J. Neurosci. 29(2): 414--424 ben Functions with scamp during synaptic transmission and long-term memory formation in Drosophila. [FBrf0206586] Shigenobu et al., 2006, Proc. Natl. Acad. Sci. USA 103(37): 13728--13733 Molecular characterization of embryonic gonads by gene expression profiling in Drosophila melanogaster. [FBrf0193273] Lipatov et al., 2005, BMC Biol. 3: 24 Paucity of chimeric gene-transposable element transcripts in the Drosophila melanogaster genome. [FBrf0189752] Wu et al., 2005, J. Neurosci. 25(42): 9557--9566 Highwire function at the Drosophila neuromuscular junction: spatial, structural, and temporal requirements. [FBrf0191056]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Perkins et al., 2009, Update to TRiP stock collection. Update to TRiP stock collection. [FBrf0208864] Bellen, 2007.5.7, batch741.xml batch741.xml [FBrf0199562] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
FlyBase analysis	FlyBase Genome Annotators, 2004, Changes affecting gene model number or type in release 3.2 of the annotated D.melanogaster genome. Changes affecting gene model number or type in release 3.2 of the annotated D.melanogaster genome. [FBrf0166453] FlyBase Genome Annotators, 2002-2003, Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. Changes affecting gene model number or type in releases 3.0 and 3.1 of the annotated D.melanogaster genome. [FBrf0148886] FlyBase Curators, 2002-, Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. Use of the ND evidence code for Gene Ontology (GO) terms in FlyBase. [FBrf0159398]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]