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Gene Dmel\CG5877

General Information
Symbol	Dmel\CG5877	Species	D. melanogaster
Name		Annotation symbol	CG5877
Feature type	protein_coding_gene	FlyBase ID	FBgn0030625
Gene Model Status	Current	Stock availability	6 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	13B4-13B5	Sequence location	X:15,187,066..15,190,836 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG5877 (FBgn0030625). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. It is reported to be involved in the biological process: nuclear mRNA splicing, via spliceosome. 5 alleles are reported. The phenotype of these alleles is annotated with: trichogen cell. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Domain of unknown function DUF1740; Protein prenyltransferase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. Comments on Affy2 ProbeSet: ProbeSet 1638618_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG5877. Gene sequence location is X:15187066..15190836.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features HFA19963 BKN26811
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 13B4-13B5   Limits computationally determined from genome sequence between P{EP}hiwEP1308 and P{EP}Ahcy13EP1007
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG5877 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG5877-RA FBtr0074001  NM_132786   3328   984 CG5877-RB FBtr0074002  NM_167434   2609   731
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG5877-PA   FBpp0073818   114.2   984   9.76     NP_573014   AAF48437 CG5877-PB   FBpp0073819   85.4   731   9.60     NP_727839   AAN09659
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Domain of unknown function DUF1740 (IPR013633) Protein prenyltransferase (IPR008940)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA567576   AA952244   AE014298 AAF48437   AE014298 AAN09659   AI515034   AI543589   AW942958   AY069561 AAL39706   BF491861   BF506157   BG639192   BI166027   BI166064   BI237683   BI358359   BI364394   BI364828   BI365981   BI483583   BI577971   CO279038   CO287276   CO333979   CO344722   CZ481103   CZ481654   EC053234   EC072723   EC079433   EC195764   EC260708   GH749645   GH749964   GH750284   GH753199   GH754770   GH755928   GH757935   GH758404   GH758635   GH759379   GH759474   GH759641   GH774243   GH774813   GH775072   GH776314   GH776718   GH779941   GH781968   GH782129   GH782476   GH782571   GH783894   GH784044   GH784203   GH784995   GH786573   GH787408   GH788849   GH789101   GH790878   GH791228   GH791856   GH792963   GH792984   GH795848   GH798118   GH799802   GH799816   GH800326   GH800531   GH800586   GH802214   GH802988   GH803040   GH803677   GH803880   GH804104   GH808136   GH808821   GH809281   GH811546   GH814362   GH814860   GH818315   GH819430   GH819544   GH819812   GH820327   GH821511   GH822485   GH825576   GH827923   GH827983   GH828260   GH828737   GH828828   GH830680   GH831844   GH835672   GH836689   GH836786   GH843182   GH844528   GH844894   GH845951   GH846094   GH848510   GH853608   GH853745   GH854734   GH858010   GH858349   GH859842   GH862785   GH863300   GH868729   GH872429   GH874411   GH874582   GH876975   GH878156   GH878689   GH879223   GH881325   GH884377   GH885106   GH888251   GH888540   GH889651   GH891462   GH893853   GH895716   GH897200   GH897734   GH905988   GH907080   GH907476   GH907594   GH909059   GH909780   GH909827   GH912263   GH912339   GH917268   GH917615   GH917724   GH918017   GH919570   GH922387   GH923705   GH924846   GH925306   GH925494   GH925544   GH927429   GH934275   GH934328   GH941108
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8IR40 Q8T048 Q9VXW9
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0030625    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0030625 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0030625 expression level Developmental Stage   Expression Level embryo 00-02hr    1518 embryo 02-04hr    1322 embryo 04-06hr    1225 embryo 06-08hr    817 embryo 08-10hr    1018 embryo 10-12hr    766 embryo 12-14hr    872 embryo 14-16hr    623 embryo 16-18hr    606 embryo 18-20hr    339 embryo 20-22hr    549 embryo 22-24hr    692 larva L1    229 larva L2    229 larva L3 12hr old    131 larva L3 puffstage 1-2    320 larva L3 puffstage 3-6    539 larva L3 puffstage 7-9    835 white prepupae new    756 white prepupae 12hr    943 white prepupae 24hr    1134 pupae 2d postWPP    1066 pupae 3d postWPP    764 pupae 4d postWPP    474 adult male 01day    820 adult male 05day    1213 adult male 30day    945 adult female 01day    408 adult female 05day    924 adult female 30day    904 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1518) embryo 02-04hr  (1322) embryo 04-06hr  (1225) embryo 06-08hr  (817) embryo 08-10hr  (1018) embryo 10-12hr  (766) embryo 12-14hr  (872) embryo 14-16hr  (623) embryo 16-18hr  (606) embryo 18-20hr  (339) embryo 20-22hr  (549) embryo 22-24hr  (692) larva L1  (229) larva L2  (229) larva L3 12hr old  (131) larva L3 puffstage 1-2  (320) larva L3 puffstage 3-6  (539) larva L3 puffstage 7-9  (835) white prepupae new  (756) white prepupae 12hr  (943) white prepupae 24hr  (1134) pupae 2d postWPP  (1066) pupae 3d postWPP  (764) pupae 4d postWPP  (474) adult male 01day  (820) adult male 05day  (1213) adult male 30day  (945) adult female 01day  (408) adult female 05day  (924) adult female 30day  (904) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (1518) embryo 02-04hr    1322 embryo 04-06hr    1225 embryo 06-08hr    817 embryo 08-10hr    1018 embryo 10-12hr    766 embryo 12-14hr    872 embryo 14-16hr    623 embryo 16-18hr    606 embryo 18-20hr    339 embryo 20-22hr    549 embryo 22-24hr    692 larva L1    229 larva L2    229 larva L3 12hr old    131 larva L3 puffstage 1-2    320 larva L3 puffstage 3-6    539 larva L3 puffstage 7-9    835 white prepupae new    756 white prepupae 12hr    943 white prepupae 24hr    1134 pupae 2d postWPP    1066 pupae 3d postWPP    764 pupae 4d postWPP    474 adult male 01day    820 adult male 05day    1213 adult male 30day    945 adult female 01day    408 adult female 05day    924 adult female 30day    904 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1518 embryo 02-04hr    1322 embryo 04-06hr    1225 embryo 06-08hr    817 embryo 08-10hr    1018 embryo 10-12hr    766 embryo 12-14hr    872 embryo 14-16hr    623 embryo 16-18hr    606 embryo 18-20hr    339 embryo 20-22hr    549 embryo 22-24hr    692 larva L1    229 larva L2    229 larva L3 12hr old    131 larva L3 puffstage 1-2    320 larva L3 puffstage 3-6    539 larva L3 puffstage 7-9    835 white prepupae new    756 white prepupae 12hr    943 white prepupae 24hr    1134 pupae 2d postWPP    1066 pupae 3d postWPP    764 pupae 4d postWPP    474 adult male 01day    820 adult male 05day    1213 adult male 30day    945 adult female 01day    408 adult female 05day    924 adult female 30day    904 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1518 embryo 02-04hr    1322 embryo 04-06hr    1225 embryo 06-08hr    817 embryo 08-10hr    1018 embryo 10-12hr    766 embryo 12-14hr    872 embryo 14-16hr    623 embryo 16-18hr    606 embryo 18-20hr    339 embryo 20-22hr    549 embryo 22-24hr    692 larva L1    229 larva L2    229 larva L3 12hr old    131 larva L3 puffstage 1-2    320 larva L3 puffstage 3-6    539 larva L3 puffstage 7-9    835 white prepupae new    756 white prepupae 12hr    943 white prepupae 24hr    1134 pupae 2d postWPP    1066 pupae 3d postWPP    764 pupae 4d postWPP    474 adult male 01day    820 adult male 05day    1213 adult male 30day    945 adult female 01day    408 adult female 05day    924 adult female 30day    904 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0030625 expression level Developmental Stage   Expression Level embryo 00-02hr    1518 embryo 02-04hr    1322 embryo 04-06hr    1225 embryo 06-08hr    817 embryo 08-10hr    1018 embryo 10-12hr    766 embryo 12-14hr    872 embryo 14-16hr    623 embryo 16-18hr    606 embryo 18-20hr    339 embryo 20-22hr    549 embryo 22-24hr    692 larva L1    229 larva L2    229 larva L3 12hr old    131 larva L3 puffstage 1-2    320 larva L3 puffstage 3-6    539 larva L3 puffstage 7-9    835 white prepupae new    756 white prepupae 12hr    943 white prepupae 24hr    1134 pupae 2d postWPP    1066 pupae 3d postWPP    764 pupae 4d postWPP    474 adult male 01day    820 adult male 05day    1213 adult male 30day    945 adult female 01day    408 adult female 05day    924 adult female 30day    904 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (1518) embryo 02-04hr  (1322) embryo 04-06hr  (1225) embryo 06-08hr  (817) embryo 08-10hr  (1018) embryo 10-12hr  (766) embryo 12-14hr  (872) embryo 14-16hr  (623) embryo 16-18hr  (606) embryo 18-20hr  (339) embryo 20-22hr  (549) embryo 22-24hr  (692) larva L1  (229) larva L2  (229) larva L3 12hr old  131 larva L3 puffstage 1-2  (320) larva L3 puffstage 3-6  (539) larva L3 puffstage 7-9  (835) white prepupae new  (756) white prepupae 12hr  (943) white prepupae 24hr  (1134) pupae 2d postWPP  (1066) pupae 3d postWPP  (764) pupae 4d postWPP  (474) adult male 01day  (820) adult male 05day  (1213) adult male 30day  (945) adult female 01day  (408) adult female 05day  (924) adult female 30day  (904) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  1518 embryo 02-04hr    1322 embryo 04-06hr    1225 embryo 06-08hr    817 embryo 08-10hr    1018 embryo 10-12hr    766 embryo 12-14hr    872 embryo 14-16hr    623 embryo 16-18hr    606 embryo 18-20hr    339 embryo 20-22hr    549 embryo 22-24hr    692 larva L1    229 larva L2    229 larva L3 12hr old    131 larva L3 puffstage 1-2    320 larva L3 puffstage 3-6    539 larva L3 puffstage 7-9    835 white prepupae new    756 white prepupae 12hr    943 white prepupae 24hr    1134 pupae 2d postWPP    1066 pupae 3d postWPP    764 pupae 4d postWPP    474 adult male 01day    820 adult male 05day    1213 adult male 30day    945 adult female 01day    408 adult female 05day    924 adult female 30day    904 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    1518 embryo 02-04hr    1322 embryo 04-06hr    1225 embryo 06-08hr    817 embryo 08-10hr    1018 embryo 10-12hr    766 embryo 12-14hr    872 embryo 14-16hr    623 embryo 16-18hr    606 embryo 18-20hr    339 embryo 20-22hr    549 embryo 22-24hr    692 larva L1    229 larva L2    229 larva L3 12hr old    131 larva L3 puffstage 1-2    320 larva L3 puffstage 3-6    539 larva L3 puffstage 7-9    835 white prepupae new    756 white prepupae 12hr    943 white prepupae 24hr    1134 pupae 2d postWPP    1066 pupae 3d postWPP    764 pupae 4d postWPP    474 adult male 01day    820 adult male 05day    1213 adult male 30day    945 adult female 01day    408 adult female 05day    924 adult female 30day    904 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    1518 embryo 02-04hr    1322 embryo 04-06hr    1225 embryo 06-08hr    817 embryo 08-10hr    1018 embryo 10-12hr    766 embryo 12-14hr    872 embryo 14-16hr    623 embryo 16-18hr    606 embryo 18-20hr    339 embryo 20-22hr    549 embryo 22-24hr    692 larva L1    229 larva L2    229 larva L3 12hr old    131 larva L3 puffstage 1-2    320 larva L3 puffstage 3-6    539 larva L3 puffstage 7-9    835 white prepupae new    756 white prepupae 12hr    943 white prepupae 24hr    1134 pupae 2d postWPP    1066 pupae 3d postWPP    764 pupae 4d postWPP    474 adult male 01day    820 adult male 05day    1213 adult male 30day    945 adult female 01day    408 adult female 05day    924 adult female 30day    904 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0030625    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0030625 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: adult testis. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0030625 expression level Tissue   Expression Level Larval Central Nervous System    57.575 Larval Midgut    28 Larval Hindgut    35.1 Larval Malpighian Tubules    38.2 Larval Fat Body    66.8 Larval Salivary Gland    48.7 Larval Trachea    31.175 Larval Carcass    35.6 Adult Head    30.7 Adult Eye    30.925 Adult Brain    47.7 Adult Thoracic-Abdominal Ganglion    41.3 Adult Crop    48.3 Adult Midgut    28.2 Adult Hindgut    45.1 Adult Malpighian Tubules    26.6 Adult Fat Body    28.3 Adult Salivary Gland    39.1 Adult Heart    18.9 Adult VirginFemale Spermatheca    31.6 Adult InseminatedFemale Spermatheca    38.1 Adult Ovary    92.5 Adult Testis    377.1 Adult Male Accessory Gland    30.1 Adult Carcass    33.6 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    57.575 Larval Midgut    28 Larval Hindgut    35.1 Larval Malpighian Tubules    38.2 Larval Fat Body    66.8 Larval Salivary Gland    48.7 Larval Trachea    31.175 Larval Carcass    35.6 Adult Head    30.7 Adult Eye    30.925 Adult Brain    47.7 Adult Thoracic-Abdominal Ganglion    41.3 Adult Crop    48.3 Adult Midgut    28.2 Adult Hindgut    45.1 Adult Malpighian Tubules    26.6 Adult Fat Body    28.3 Adult Salivary Gland    39.1 Adult Heart    18.9 Adult VirginFemale Spermatheca    31.6 Adult InseminatedFemale Spermatheca    38.1 Adult Ovary    92.5 Adult Testis    377.1 Adult Male Accessory Gland    30.1 Adult Carcass    33.6 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    57.575 Larval Midgut    28 Larval Hindgut    35.1 Larval Malpighian Tubules    38.2 Larval Fat Body    66.8 Larval Salivary Gland    48.7 Larval Trachea    31.175 Larval Carcass    35.6 Adult Head    30.7 Adult Eye    30.925 Adult Brain    47.7 Adult Thoracic-Abdominal Ganglion    41.3 Adult Crop    48.3 Adult Midgut    28.2 Adult Hindgut    45.1 Adult Malpighian Tubules    26.6 Adult Fat Body    28.3 Adult Salivary Gland    39.1 Adult Heart    18.9 Adult VirginFemale Spermatheca    31.6 Adult InseminatedFemale Spermatheca    38.1 Adult Ovary    92.5 Adult Testis    377.1 Adult Male Accessory Gland    30.1 Adult Carcass    33.6 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    57.575 Larval Midgut    28 Larval Hindgut    35.1 Larval Malpighian Tubules    38.2 Larval Fat Body    66.8 Larval Salivary Gland    48.7 Larval Trachea    31.175 Larval Carcass    35.6 Adult Head    30.7 Adult Eye    30.925 Adult Brain    47.7 Adult Thoracic-Abdominal Ganglion    41.3 Adult Crop    48.3 Adult Midgut    28.2 Adult Hindgut    45.1 Adult Malpighian Tubules    26.6 Adult Fat Body    28.3 Adult Salivary Gland    39.1 Adult Heart    18.9 Adult VirginFemale Spermatheca    31.6 Adult InseminatedFemale Spermatheca    38.1 Adult Ovary    92.5 Adult Testis    377.1 Adult Male Accessory Gland    30.1 Adult Carcass    33.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0030625 expression level Tissue   Expression Level Larval Central Nervous System    57.575 Larval Midgut    28 Larval Hindgut    35.1 Larval Malpighian Tubules    38.2 Larval Fat Body    66.8 Larval Salivary Gland    48.7 Larval Trachea    31.175 Larval Carcass    35.6 Adult Head    30.7 Adult Eye    30.925 Adult Brain    47.7 Adult Thoracic-Abdominal Ganglion    41.3 Adult Crop    48.3 Adult Midgut    28.2 Adult Hindgut    45.1 Adult Malpighian Tubules    26.6 Adult Fat Body    28.3 Adult Salivary Gland    39.1 Adult Heart    18.9 Adult VirginFemale Spermatheca    31.6 Adult InseminatedFemale Spermatheca    38.1 Adult Ovary    92.5 Adult Testis    377.1 Adult Male Accessory Gland    30.1 Adult Carcass    33.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    57.575 Larval Midgut    28 Larval Hindgut    35.1 Larval Malpighian Tubules    38.2 Larval Fat Body    66.8 Larval Salivary Gland    48.7 Larval Trachea    31.175 Larval Carcass    35.6 Adult Head    30.7 Adult Eye    30.925 Adult Brain    47.7 Adult Thoracic-Abdominal Ganglion    41.3 Adult Crop    48.3 Adult Midgut    28.2 Adult Hindgut    45.1 Adult Malpighian Tubules    26.6 Adult Fat Body    28.3 Adult Salivary Gland    39.1 Adult Heart    18.9 Adult VirginFemale Spermatheca    31.6 Adult InseminatedFemale Spermatheca    38.1 Adult Ovary    92.5 Adult Testis    377.1 Adult Male Accessory Gland    30.1 Adult Carcass    33.6 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    57.575 Larval Midgut    28 Larval Hindgut    35.1 Larval Malpighian Tubules    38.2 Larval Fat Body    66.8 Larval Salivary Gland    48.7 Larval Trachea    31.175 Larval Carcass    35.6 Adult Head    30.7 Adult Eye    30.925 Adult Brain    47.7 Adult Thoracic-Abdominal Ganglion    41.3 Adult Crop    48.3 Adult Midgut    28.2 Adult Hindgut    45.1 Adult Malpighian Tubules    26.6 Adult Fat Body    28.3 Adult Salivary Gland    39.1 Adult Heart    18.9 Adult VirginFemale Spermatheca    31.6 Adult InseminatedFemale Spermatheca    38.1 Adult Ovary    92.5 Adult Testis    377.1 Adult Male Accessory Gland    30.1 Adult Carcass    33.6 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    57.575 Larval Midgut    28 Larval Hindgut    35.1 Larval Malpighian Tubules    38.2 Larval Fat Body    66.8 Larval Salivary Gland    48.7 Larval Trachea    31.175 Larval Carcass    35.6 Adult Head    30.7 Adult Eye    30.925 Adult Brain    47.7 Adult Thoracic-Abdominal Ganglion    41.3 Adult Crop    48.3 Adult Midgut    28.2 Adult Hindgut    45.1 Adult Malpighian Tubules    26.6 Adult Fat Body    28.3 Adult Salivary Gland    39.1 Adult Heart    18.9 Adult VirginFemale Spermatheca    31.6 Adult InseminatedFemale Spermatheca    38.1 Adult Ovary    92.5 Adult Testis    377.1 Adult Male Accessory Gland    30.1 Adult Carcass    33.6 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    30.7   NA  Eye    30.925   NA  Brain    47.7   57.575  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    41.3   NA  Crop    48.3   28  Midgut    28.2   35.1  Hindgut    45.1   38.2  Malpighian Tubules    26.6   66.8  Fat Body    28.3   48.7  Salivary Gland    39.1   NA  Heart    18.9   31.175  Trachea    NA   NA  VirginFemale Spermatheca    31.6   NA  InseminatedFemale Spermatheca    38.1   NA  Ovary    92.5   NA  Testis    377.1   NA  Male Accessory Gland    30.1   35.6  Carcass    33.6 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_21
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030625 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5877-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable CG5877f05770 viable, with Scer\GAL4pnr-MD237 CG5877GD11792 Sterility Allele fertile CG5877f05770 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 CG5877GD11792 Phenotype manifest in Allele trichogen cell, with Scer\GAL4pnr-MD237 CG5877GD11792
Classical Alleles ( 4 )
For All Classical Alleles Show
Allele of CG5877 Class Mutagen Stocks Known lesion CG5877f05770 piggyBac transposase 2 -- CG5877e03330 piggyBac transposase 1 -- CG5877e03895 piggyBac transposase 1 -- CG5877MB07078 1 --
Alleles Carried on Transgenic Constructs ( 1 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG5877 Class Mutagen Stocks Known lesion CG5877GD11792 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD11792} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{RB}CG5877e03330 NA PBac{RB}CG5877e03895 NA PBac{WH}CG5877f05770 NA insertion of enhancer trap binary system Mi{ET1}CG5877MB07078 No
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
catalytic step 2 spliceosome inferred from direct assay (Herold et al., 2009)
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
nuclear mRNA splicing, via spliceosome inferred by curator from GO:0071013 (Herold et al., 2009)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG5877 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 58810 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030625 DroID - A comprehensive database of gene and protein interactions. • FBgn0030625 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32455
Orthologs
Genome-wide drosophilid orthologs	Dana\GF21230 Dere\GG17871 Dgri\GH17615 Dmoj\GI21771 Dper\GL15996 Dpse\GA24354 Dsec\GM19624 Dsim\GD17202 Dvir\GJ16943 Dwil\GK16198 Dyak\GE17173
Curated drosophilid orthologs
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL010459-PA Aedes aegypti (mosquito) AGAP010680-PA Anopheles gambiae (mosquito) XP_001943402.1 Acyrthosiphon pisum (pea aphid) At3g17740.1 Arabidopsis thaliana (wall cress) 91264 Batrachochytrium dendrobatidis (chytrid fungus) 103862 Branchiostoma floridae (lancelet) XP_001900847.1 Brugia malayi (roundworm nematode) ENSBTAP00000007147 Bos taurus (bovine) CPIJ004421 Culex pipens (mosquito) 52247 Capitella spl (polychaete worm) 308050 Daphnia pulex (daphnia) ENSECAP00000003286 Equus caballus (horse) ENSGACP00000016692 Gymnopilus aculeatus (mushroom) ENSGALP00000017349 Gallus gallus (chicken) ENSP00000346335 Homo sapiens (human) 143344 Lottia gigantea (owl limpet) ENSMMUP00000013691 Macaca mulatta (rhesus monkey) ENSMUSP00000021596 Mus musculus (house mouse) 241809 Nematostella vectensis (starlet anemone) XP_001602156.1 Nasonia vitripennis (wasp) LOC_Os02g53270.1 Oryza sativa (asian rice) 30263 Ostreococcus tauri (green alga) PHUM010245-PA Pediculus humanus (human body louse) 165542 Physcomitrella patens (moss) 265832 Populus trichocarpa (black cottonwood) ENSPTRP00000052537 Pan troglodytes (chimpanzee) ENSRNOP00000005369 Rattus norvegicus (norway rat) 4884832 Sorghum bicolor (sorghum) XP_799278.2 Strongylocentrotus purpuratus (purple sea urchin) 30197 Trichoplax adhaerens (metazoa) XP_969760.1 Tribolium castaneum (red flour beetle) ENSTRUP00000006510 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000034250 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV14279 LH15816 ISCW001175 FBgn0234652 FBgn0218200 FBgn0204121 FBgn0188766 FBgn0174524 JGI_V11_308050 FBgn0245751 FBgn0153600 FBgn0144501 FBgn0125085 FBgn0110091 FBgn0098232 CPIJ004421 ACYPI005085 GB15071 AGAP010680 AAEL010459 PB20633 PHUM491890 GLEAN_00974
Stocks & Reagents
Stocks Listed in FlyBase ( 6 )
Bloomington	18904 w1118 PBac{WH}CG5877f05770 26068 w1118 Mi{ET1}CG5877MB07078
Harvard	- PBac{RB}CG5877e03330 - PBac{RB}CG5877e03895 - PBac{WH}CG5877f05770
VDRC	v39004 w1118; P{GD11792}v39004
Genomic Clones ( 1 )
	BACR48D17 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 154 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD29352
Other clones	DPiM_LD29352
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT08557 AT28624 HL01476 RE06046 RE06085 RE33956 RE45110 RE49490 RE50016 RE51390 RE66496 RE71752 SD10386
Other clones	19397 214479.34 282827 CK01.69B.G11 EC053234 EK065421 EK133325 EK308525 EP19763 LD46702 RP003006544 RP003038807 RP003047421 RP003057239 RP003060613 RP003061561 RP003063151 RP003066326 RP003069021 RP003073934 RP003076618 RP003104792 RP003105673 RP003109062 RP003119224 RP003126083 RP003126334 RP003126818 RP003133049 RP003134169 RP003146051 RP003148644 RP003149218 RP003152177 RP003153414 RP003156442 RP003161071 RP003163778 RP003187118 RP003189395 RP003194745 RP003197567 RP003198511 RP003200912 RP003203831 RP003213147 RP003221481 RP003221632 RP003228216 RP003235110 RP003244185 RP003254071 RP003258943 RP003260119 RP003261309 RP003261613 RP003261725 RP003266947 RP003270296 RP003287668 RP003291694 RP003292544 RP003293450 RP003299935 RP003302206 RP003303116 RP003312787 RP003314376 RP003323852 RP003323926 RP003324976 RP003326028 RP003326577 RP003329037 RP003329658 RP003329972 RP003332966 RP003333184 RP003334047 RP003337070 RP003343900 RP003354404 RP003359755 RP003362811 RP003366178 RP003367586 RP003374684 RP003375845 RP003378221 RP003380168 RP003381850 RP003389790 RP003391742 RP003408458 RP003421780 RP003429154 RP003430935 RP003454970 RP003467630 RP003471597 RP003471625 RP003479959 RP003480858 RP003490142 RP003496322 RP003503310 RP003503545 RP003513829 RP003520401 RP003528505 RP003531479 RP003537110 RP003541430 RP003542671 RP003549687 RP003552375 RP003557028 RP003563930 RP003575412 RP003590902 RP003597477 RP003600695 RP003613211 RP003617871 RP003624497 RP003625448 RP003626712 RP003628585 RP003633456 RP003640180 RP003642063 RP003646984 RP003660328 RP003662904 RP003667018 RP003670103 RP003675667 RP003677160 RP003681460
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030625 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32455
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132786 NM_167434 RefSeq (Proteins) • NP_573014 NP_727839 DDBJ / EMBL / GenBank • AA952244 AAF48437 AAL39706 AAN09659 AW942958 AY069561 CZ481103 CZ481654 Entrez Gene - A searchable database of RefSeq genes. • 32455 UniProtKB/TrEMBL • Q8IR40 Q8T048 Q9VXW9
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Domain of unknown function DUF1740 (IPR013633) Protein prenyltransferase (IPR008940)
Linkouts
	BioGRID - A database of protein and genetic interactions • 58810 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030625 DroID - A comprehensive database of gene and protein interactions. • FBgn0030625 DRSC - Results from RNAi screens. • FBgn0030625 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030625 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG5877-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030625 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32455 InParanoid A subset of ortholog calls from InParanoid. • AAEL010459-PA Aedes aegypti (mosquito) AGAP010680-PA Anopheles gambiae (mosquito) XP_001943402.1 Acyrthosiphon pisum (pea aphid) At3g17740.1 Arabidopsis thaliana (wall cress) 91264 Batrachochytrium dendrobatidis (chytrid fungus) 103862 Branchiostoma floridae (lancelet) XP_001900847.1 Brugia malayi (roundworm nematode) ENSBTAP00000007147 Bos taurus (bovine) CPIJ004421 Culex pipens (mosquito) 52247 Capitella spl (polychaete worm) 308050 Daphnia pulex (daphnia) ENSECAP00000003286 Equus caballus (horse) ENSGACP00000016692 Gymnopilus aculeatus (mushroom) ENSGALP00000017349 Gallus gallus (chicken) ENSP00000346335 Homo sapiens (human) 143344 Lottia gigantea (owl limpet) ENSMMUP00000013691 Macaca mulatta (rhesus monkey) ENSMUSP00000021596 Mus musculus (house mouse) 241809 Nematostella vectensis (starlet anemone) XP_001602156.1 Nasonia vitripennis (wasp) LOC_Os02g53270.1 Oryza sativa (asian rice) 30263 Ostreococcus tauri (green alga) PHUM010245-PA Pediculus humanus (human body louse) 165542 Physcomitrella patens (moss) 265832 Populus trichocarpa (black cottonwood) ENSPTRP00000052537 Pan troglodytes (chimpanzee) ENSRNOP00000005369 Rattus norvegicus (norway rat) 4884832 Sorghum bicolor (sorghum) XP_799278.2 Strongylocentrotus purpuratus (purple sea urchin) 30197 Trichoplax adhaerens (metazoa) XP_969760.1 Tribolium castaneum (red flour beetle) ENSTRUP00000006510 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000034250 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32455 modMine - Data generated by the modENCODE project. • FBgn0030625 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV14279 LH15816 ISCW001175 FBgn0234652 FBgn0218200 FBgn0204121 FBgn0188766 FBgn0174524 JGI_V11_308050 FBgn0245751 FBgn0153600 FBgn0144501 FBgn0125085 FBgn0110091 FBgn0098232 CPIJ004421 ACYPI005085 GB15071 AGAP010680 AAEL010459 PB20633 PHUM491890 GLEAN_00974
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG5877 (Herold et al., 2009, Baumann et al., 2010)
Name Synonym
Secondary FlyBase IDs
References ( 12 )
Research paper	Baumann et al., 2010, J. Insect Physiol. 56(10): 1445--1455 Evolutionary divergence of the paralogs Methoprene tolerant (Met) and germ cell expressed (gce) within the genus Drosophila. [FBrf0211455] Herold et al., 2009, Mol. Cell. Biol. 29(1): 281--301 Conservation of the protein composition and electron microscopy structure of Drosophila melanogaster and human spliceosomal complexes. [FBrf0207172]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Bellen, 2008.11.7, set816.xml set816.xml [FBrf0206132] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] Bloomington Drosophila Stock Center, 2004.11.6, Exelixis insertion alleles that are not in FlyBase. Exelixis insertion alleles that are not in FlyBase. [FBrf0179797]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]