General Information Symbol Dmel\ CG9220Species D. melanogaster Name Annotation symbol CG9220 Feature type protein_coding_gene FlyBase ID FBgn0030662 Gene Model Status Current Stock availability 3 publicly
available Genomic Location Chromosome (arm) X Recombination map Cytogenetic map 13D4-13E1 Sequence location X:15,479,322..15,487,567 [-]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information This gene is referred to in FlyBase by the symbol
Dmel\CG9220 (FBgn0030662). It is a protein_coding_gene from
Drosophila melanogaster . It is reported to have
molecular function : glucuronosyltransferase activity; acetylglucosaminyltransferase activity. It is reported to be involved in the
biological process : chondroitin sulfate biosynthetic process.
3 alleles are reported . The
phenotype of these alleles is annotated with: mesothoracic tergum. It has
2 annotated transcripts and
2 annotated polypeptides .
Protein features are: Chondroitin N-acetylgalactosaminyltransferase. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of very low expression. Peak expression observed within 06-12 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Two or more Affy2 ProbeSets identify exons of this gene. This is a summary of the tissue expression peaks exhibited in at least one of these ProbeSets. Expression at moderate levels in the following post-embryonic organs or tissues: larval fat body. Gene sequence location is
X:15479322..15487567 .
User Contributed Data
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.50
Low-frequency RNA-Seq exon junction(s) not annotated.
Annotated transcripts do not represent all supported alternative splices within 5' UTR.
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript Expression
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
6
central nervous system, larvae L3
6
central nervous system, pupae P8
3
head, virgin 1-day female
5
head, virgin 4-day female
3
head, virgin 20-day female
3
head, mated 1-day female
2
head, mated 4-day female
2
head, mated 20-day female
3
head, mated 1-day male
5
head, mated 4-day male
5
head, mated 20-day male
7
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
2
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
4
digestive system, 4-day adult
5
digestive system, 20-day adult
5
fat body, larvae L3 wandering
4
fat body, white prepupae
4
fat body, pupae P8
4
carcass, larvae L3 wandering
9
carcass, 1-day adult
3
carcass, 4-day adult
4
carcass, 20-day adult
4
ovary, virgin 4-day female
1
ovary, mated 4-day female
1
testis, mated 4-day male
1
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
6
central nervous system, larvae L3
6
central nervous system, pupae P8
3
head, virgin 1-day female
5
head, virgin 4-day female
3
head, virgin 20-day female
3
head, mated 1-day female
2
head, mated 4-day female
2
head, mated 20-day female
3
head, mated 1-day male
5
head, mated 4-day male
5
head, mated 20-day male
7
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
2
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
4
digestive system, 4-day adult
5
digestive system, 20-day adult
5
fat body, larvae L3 wandering
4
fat body, white prepupae
4
fat body, pupae P8
4
carcass, larvae L3 wandering
9
carcass, 1-day adult
3
carcass, 4-day adult
4
carcass, 20-day adult
4
ovary, virgin 4-day female
1
ovary, mated 4-day female
1
testis, mated 4-day male
1
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
6
central nervous system, larvae L3
6
central nervous system, pupae P8
3
head, virgin 1-day female
5
head, virgin 4-day female
3
head, virgin 20-day female
3
head, mated 1-day female
2
head, mated 4-day female
2
head, mated 20-day female
3
head, mated 1-day male
5
head, mated 4-day male
5
head, mated 20-day male
7
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
2
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
4
digestive system, 4-day adult
5
digestive system, 20-day adult
5
fat body, larvae L3 wandering
4
fat body, white prepupae
4
fat body, pupae P8
4
carcass, larvae L3 wandering
9
carcass, 1-day adult
3
carcass, 4-day adult
4
carcass, 20-day adult
4
ovary, virgin 4-day female
1
ovary, mated 4-day female
1
testis, mated 4-day male
1
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
6
central nervous system, larvae L3
6
central nervous system, pupae P8
3
head, virgin 1-day female
5
head, virgin 4-day female
3
head, virgin 20-day female
3
head, mated 1-day female
2
head, mated 4-day female
2
head, mated 20-day female
3
head, mated 1-day male
5
head, mated 4-day male
5
head, mated 20-day male
7
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
2
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
4
digestive system, 4-day adult
5
digestive system, 20-day adult
5
fat body, larvae L3 wandering
4
fat body, white prepupae
4
fat body, pupae P8
4
carcass, larvae L3 wandering
9
carcass, 1-day adult
3
carcass, 4-day adult
4
carcass, 20-day adult
4
ovary, virgin 4-day female
1
ovary, mated 4-day female
1
testis, mated 4-day male
1
accessory gland, mated 4-day male
2
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
6
central nervous system, larvae L3
6
central nervous system, pupae P8
3
head, virgin 1-day female
5
head, virgin 4-day female
3
head, virgin 20-day female
3
head, mated 1-day female
2
head, mated 4-day female
2
head, mated 20-day female
3
head, mated 1-day male
5
head, mated 4-day male
5
head, mated 20-day male
7
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
2
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
4
digestive system, 4-day adult
5
digestive system, 20-day adult
5
fat body, larvae L3 wandering
4
fat body, white prepupae
4
fat body, pupae P8
4
carcass, larvae L3 wandering
9
carcass, 1-day adult
3
carcass, 4-day adult
4
carcass, 20-day adult
4
ovary, virgin 4-day female
1
ovary, mated 4-day female
1
testis, mated 4-day male
1
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
6
central nervous system, larvae L3
6
central nervous system, pupae P8
3
head, virgin 1-day female
5
head, virgin 4-day female
3
head, virgin 20-day female
3
head, mated 1-day female
2
head, mated 4-day female
2
head, mated 20-day female
3
head, mated 1-day male
5
head, mated 4-day male
5
head, mated 20-day male
7
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
2
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
4
digestive system, 4-day adult
5
digestive system, 20-day adult
5
fat body, larvae L3 wandering
4
fat body, white prepupae
4
fat body, pupae P8
4
carcass, larvae L3 wandering
9
carcass, 1-day adult
3
carcass, 4-day adult
4
carcass, 20-day adult
4
ovary, virgin 4-day female
1
ovary, mated 4-day female
1
testis, mated 4-day male
1
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
6
central nervous system, larvae L3
6
central nervous system, pupae P8
3
head, virgin 1-day female
5
head, virgin 4-day female
3
head, virgin 20-day female
3
head, mated 1-day female
2
head, mated 4-day female
2
head, mated 20-day female
3
head, mated 1-day male
5
head, mated 4-day male
5
head, mated 20-day male
7
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
2
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
4
digestive system, 4-day adult
5
digestive system, 20-day adult
5
fat body, larvae L3 wandering
4
fat body, white prepupae
4
fat body, pupae P8
4
carcass, larvae L3 wandering
9
carcass, 1-day adult
3
carcass, 4-day adult
4
carcass, 20-day adult
4
ovary, virgin 4-day female
1
ovary, mated 4-day female
1
testis, mated 4-day male
1
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
6
central nervous system, larvae L3
6
central nervous system, pupae P8
3
head, virgin 1-day female
5
head, virgin 4-day female
3
head, virgin 20-day female
3
head, mated 1-day female
2
head, mated 4-day female
2
head, mated 20-day female
3
head, mated 1-day male
5
head, mated 4-day male
5
head, mated 20-day male
7
salivary gland, larvae L3 wandering
1
salivary gland, white prepupae
2
digestive system, larvae L3 wandering
4
digestive system, 1-day adult
4
digestive system, 4-day adult
5
digestive system, 20-day adult
5
fat body, larvae L3 wandering
4
fat body, white prepupae
4
fat body, pupae P8
4
carcass, larvae L3 wandering
9
carcass, 1-day adult
3
carcass, 4-day adult
4
carcass, 20-day adult
4
ovary, virgin 4-day female
1
ovary, mated 4-day female
1
testis, mated 4-day male
1
accessory gland, mated 4-day male
2
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
0
embryo 02-04hr
3
embryo 04-06hr
11
embryo 06-08hr
17
embryo 08-10hr
12
embryo 10-12hr
11
embryo 12-14hr
9
embryo 14-16hr
10
embryo 16-18hr
9
embryo 18-20hr
10
embryo 20-22hr
11
embryo 22-24hr
12
larva L1
15
larva L2
11
larva L3 12hr old
7
larva L3 puffstage 1-2
6
larva L3 puffstage 3-6
11
larva L3 puffstage 7-9
13
white prepupae new
7
white prepupae 12hr
12
white prepupae 24hr
15
pupae 2d postWPP
10
pupae 3d postWPP
7
pupae 4d postWPP
6
adult male 01day
6
adult male 05day
8
adult male 30day
8
adult female 01day
7
adult female 05day
4
adult female 30day
4
Expression Level Scale
Very low
Low
Moderate
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
0
embryo 02-04hr
3
embryo 04-06hr
11
embryo 06-08hr
17
embryo 08-10hr
12
embryo 10-12hr
11
embryo 12-14hr
9
embryo 14-16hr
10
embryo 16-18hr
9
embryo 18-20hr
10
embryo 20-22hr
11
embryo 22-24hr
12
larva L1
15
larva L2
11
larva L3 12hr old
7
larva L3 puffstage 1-2
6
larva L3 puffstage 3-6
11
larva L3 puffstage 7-9
13
white prepupae new
7
white prepupae 12hr
12
white prepupae 24hr
15
pupae 2d postWPP
10
pupae 3d postWPP
7
pupae 4d postWPP
6
adult male 01day
6
adult male 05day
8
adult male 30day
8
adult female 01day
7
adult female 05day
4
adult female 30day
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
0
embryo 02-04hr
3
embryo 04-06hr
11
embryo 06-08hr
17
embryo 08-10hr
12
embryo 10-12hr
11
embryo 12-14hr
9
embryo 14-16hr
10
embryo 16-18hr
9
embryo 18-20hr
10
embryo 20-22hr
11
embryo 22-24hr
12
larva L1
15
larva L2
11
larva L3 12hr old
7
larva L3 puffstage 1-2
6
larva L3 puffstage 3-6
11
larva L3 puffstage 7-9
13
white prepupae new
7
white prepupae 12hr
12
white prepupae 24hr
15
pupae 2d postWPP
10
pupae 3d postWPP
7
pupae 4d postWPP
6
adult male 01day
6
adult male 05day
8
adult male 30day
8
adult female 01day
7
adult female 05day
4
adult female 30day
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
0
embryo 02-04hr
3
embryo 04-06hr
11
embryo 06-08hr
17
embryo 08-10hr
12
embryo 10-12hr
11
embryo 12-14hr
9
embryo 14-16hr
10
embryo 16-18hr
9
embryo 18-20hr
10
embryo 20-22hr
11
embryo 22-24hr
12
larva L1
15
larva L2
11
larva L3 12hr old
7
larva L3 puffstage 1-2
6
larva L3 puffstage 3-6
11
larva L3 puffstage 7-9
13
white prepupae new
7
white prepupae 12hr
12
white prepupae 24hr
15
pupae 2d postWPP
10
pupae 3d postWPP
7
pupae 4d postWPP
6
adult male 01day
6
adult male 05day
8
adult male 30day
8
adult female 01day
7
adult female 05day
4
adult female 30day
4
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
0
embryo 02-04hr
3
embryo 04-06hr
11
embryo 06-08hr
17
embryo 08-10hr
12
embryo 10-12hr
11
embryo 12-14hr
9
embryo 14-16hr
10
embryo 16-18hr
9
embryo 18-20hr
10
embryo 20-22hr
11
embryo 22-24hr
12
larva L1
15
larva L2
11
larva L3 12hr old
7
larva L3 puffstage 1-2
6
larva L3 puffstage 3-6
11
larva L3 puffstage 7-9
13
white prepupae new
7
white prepupae 12hr
12
white prepupae 24hr
15
pupae 2d postWPP
10
pupae 3d postWPP
7
pupae 4d postWPP
6
adult male 01day
6
adult male 05day
8
adult male 30day
8
adult female 01day
7
adult female 05day
4
adult female 30day
4
Expression Level Scale
Very low
Low
Moderate
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
0
embryo 02-04hr
3
embryo 04-06hr
11
embryo 06-08hr
17
embryo 08-10hr
12
embryo 10-12hr
11
embryo 12-14hr
9
embryo 14-16hr
10
embryo 16-18hr
9
embryo 18-20hr
10
embryo 20-22hr
11
embryo 22-24hr
12
larva L1
15
larva L2
11
larva L3 12hr old
7
larva L3 puffstage 1-2
6
larva L3 puffstage 3-6
11
larva L3 puffstage 7-9
13
white prepupae new
7
white prepupae 12hr
12
white prepupae 24hr
15
pupae 2d postWPP
10
pupae 3d postWPP
7
pupae 4d postWPP
6
adult male 01day
6
adult male 05day
8
adult male 30day
8
adult female 01day
7
adult female 05day
4
adult female 30day
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
0
embryo 02-04hr
3
embryo 04-06hr
11
embryo 06-08hr
17
embryo 08-10hr
12
embryo 10-12hr
11
embryo 12-14hr
9
embryo 14-16hr
10
embryo 16-18hr
9
embryo 18-20hr
10
embryo 20-22hr
11
embryo 22-24hr
12
larva L1
15
larva L2
11
larva L3 12hr old
7
larva L3 puffstage 1-2
6
larva L3 puffstage 3-6
11
larva L3 puffstage 7-9
13
white prepupae new
7
white prepupae 12hr
12
white prepupae 24hr
15
pupae 2d postWPP
10
pupae 3d postWPP
7
pupae 4d postWPP
6
adult male 01day
6
adult male 05day
8
adult male 30day
8
adult female 01day
7
adult female 05day
4
adult female 30day
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
0
embryo 02-04hr
3
embryo 04-06hr
11
embryo 06-08hr
17
embryo 08-10hr
12
embryo 10-12hr
11
embryo 12-14hr
9
embryo 14-16hr
10
embryo 16-18hr
9
embryo 18-20hr
10
embryo 20-22hr
11
embryo 22-24hr
12
larva L1
15
larva L2
11
larva L3 12hr old
7
larva L3 puffstage 1-2
6
larva L3 puffstage 3-6
11
larva L3 puffstage 7-9
13
white prepupae new
7
white prepupae 12hr
12
white prepupae 24hr
15
pupae 2d postWPP
10
pupae 3d postWPP
7
pupae 4d postWPP
6
adult male 01day
6
adult male 05day
8
adult male 30day
8
adult female 01day
7
adult female 05day
4
adult female 30day
4
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
5
Schneider line 2 Sg4
42
embryonic 1182-4H
41
embryonic GM2
23
embryonic Kc167
10
embryonic S1
1
embryonic S3
35
leg disc CME L1
39
wing disc CME-W2
11
wing disc ML-DmD8
14
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
3
wing disc ML-DmD21
32
wing disc ML-DmD32
17
haltere disc ML-DmD17-c3
29
eye-antennal disc ML-DmD11
2
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
20
CNS ML-DmBG1-c1
0
CNS ML-DmBG2-c2
0
tumorous blood cells mbn2
20
ovary fGS/OSS
12
ovary OSC
10
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
5
Schneider line 2 Sg4
(42)
embryonic 1182-4H
(41)
embryonic GM2
23
embryonic Kc167
10
embryonic S1
1
embryonic S3
(35)
leg disc CME L1
(39)
wing disc CME-W2
11
wing disc ML-DmD8
14
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
3
wing disc ML-DmD21
(32)
wing disc ML-DmD32
17
haltere disc ML-DmD17-c3
(29)
eye-antennal disc ML-DmD11
2
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
20
CNS ML-DmBG1-c1
0
CNS ML-DmBG2-c2
0
tumorous blood cells mbn2
20
ovary fGS/OSS
12
ovary OSC
10
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
5
Schneider line 2 Sg4
42
embryonic 1182-4H
41
embryonic GM2
23
embryonic Kc167
10
embryonic S1
1
embryonic S3
35
leg disc CME L1
39
wing disc CME-W2
11
wing disc ML-DmD8
14
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
3
wing disc ML-DmD21
32
wing disc ML-DmD32
17
haltere disc ML-DmD17-c3
29
eye-antennal disc ML-DmD11
2
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
20
CNS ML-DmBG1-c1
0
CNS ML-DmBG2-c2
0
tumorous blood cells mbn2
20
ovary fGS/OSS
12
ovary OSC
10
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
5
Schneider line 2 Sg4
42
embryonic 1182-4H
41
embryonic GM2
23
embryonic Kc167
10
embryonic S1
1
embryonic S3
35
leg disc CME L1
39
wing disc CME-W2
11
wing disc ML-DmD8
14
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
3
wing disc ML-DmD21
32
wing disc ML-DmD32
17
haltere disc ML-DmD17-c3
29
eye-antennal disc ML-DmD11
2
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
20
CNS ML-DmBG1-c1
0
CNS ML-DmBG2-c2
0
tumorous blood cells mbn2
20
ovary fGS/OSS
12
ovary OSC
10
ovary OSS
11
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
5
Schneider line 2 Sg4
42
embryonic 1182-4H
41
embryonic GM2
23
embryonic Kc167
10
embryonic S1
1
embryonic S3
35
leg disc CME L1
39
wing disc CME-W2
11
wing disc ML-DmD8
14
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
3
wing disc ML-DmD21
32
wing disc ML-DmD32
17
haltere disc ML-DmD17-c3
29
eye-antennal disc ML-DmD11
2
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
20
CNS ML-DmBG1-c1
0
CNS ML-DmBG2-c2
0
tumorous blood cells mbn2
20
ovary fGS/OSS
12
ovary OSC
10
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
5
Schneider line 2 Sg4
(42)
embryonic 1182-4H
(41)
embryonic GM2
23
embryonic Kc167
10
embryonic S1
1
embryonic S3
(35)
leg disc CME L1
(39)
wing disc CME-W2
11
wing disc ML-DmD8
14
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
3
wing disc ML-DmD21
32
wing disc ML-DmD32
17
haltere disc ML-DmD17-c3
29
eye-antennal disc ML-DmD11
2
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
20
CNS ML-DmBG1-c1
0
CNS ML-DmBG2-c2
0
tumorous blood cells mbn2
20
ovary fGS/OSS
12
ovary OSC
10
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
5
Schneider line 2 Sg4
42
embryonic 1182-4H
41
embryonic GM2
23
embryonic Kc167
10
embryonic S1
1
embryonic S3
35
leg disc CME L1
39
wing disc CME-W2
11
wing disc ML-DmD8
14
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
3
wing disc ML-DmD21
32
wing disc ML-DmD32
17
haltere disc ML-DmD17-c3
29
eye-antennal disc ML-DmD11
2
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
20
CNS ML-DmBG1-c1
0
CNS ML-DmBG2-c2
0
tumorous blood cells mbn2
20
ovary fGS/OSS
12
ovary OSC
10
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
5
Schneider line 2 Sg4
42
embryonic 1182-4H
41
embryonic GM2
23
embryonic Kc167
10
embryonic S1
1
embryonic S3
35
leg disc CME L1
39
wing disc CME-W2
11
wing disc ML-DmD8
14
wing disc ML-DmD9
18
wing disc ML-DmD16-c3
3
wing disc ML-DmD21
32
wing disc ML-DmD32
17
haltere disc ML-DmD17-c3
29
eye-antennal disc ML-DmD11
2
antennal disc ML-DmD20-c5
0
mixed discs ML-DmD4-c1
20
CNS ML-DmBG1-c1
0
CNS ML-DmBG2-c2
0
tumorous blood cells mbn2
20
ovary fGS/OSS
12
ovary OSC
10
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
3
cold shock, 4-day adult
2
heat shock, 4-day adult
3
Cadmium 50 mM 6 hrs, larvae L3
4
Cadmium 50 mM 12 hrs, larvae L3
2
Cadmium 50 mM 48 hrs, 4-day adult
2
Cadmium 100 mM 48 hrs, 4-day adult
2
Copper 0.5 mM 12 hrs, larvae L3
3
Copper 15 mM 48 hrs, 4-day adult
1
Zinc 5 mM 12 hrs, larvae L3
2
Zinc 4.5 mM 48 hrs, 4-day adult
3
Ethanol 2.5% 3 hrs, larvae L3
2
Ethanol 5% 3 hrs, larvae L3
3
Ethanol 10% 3 hrs, larvae L3
3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
2
Caffeine 25 mg/ml 48 hrs, 4-day adult
1
Paraquat 5 mM 48 hrs, 4-day adult
4
Paraquat 10 mM 48 hrs, 4-day adult
5
Rotenone 2 μg 12 hrs, larvae L3
4
Rotenone 8 μg 12 hrs, larvae L3
5
Expression Level Scale
Very low
Low
Moderate
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
3
cold shock, 4-day adult
2
heat shock, 4-day adult
3
Cadmium 50 mM 6 hrs, larvae L3
4
Cadmium 50 mM 12 hrs, larvae L3
2
Cadmium 50 mM 48 hrs, 4-day adult
2
Cadmium 100 mM 48 hrs, 4-day adult
2
Copper 0.5 mM 12 hrs, larvae L3
3
Copper 15 mM 48 hrs, 4-day adult
1
Zinc 5 mM 12 hrs, larvae L3
2
Zinc 4.5 mM 48 hrs, 4-day adult
3
Ethanol 2.5% 3 hrs, larvae L3
2
Ethanol 5% 3 hrs, larvae L3
3
Ethanol 10% 3 hrs, larvae L3
3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
2
Caffeine 25 mg/ml 48 hrs, 4-day adult
1
Paraquat 5 mM 48 hrs, 4-day adult
4
Paraquat 10 mM 48 hrs, 4-day adult
5
Rotenone 2 μg 12 hrs, larvae L3
4
Rotenone 8 μg 12 hrs, larvae L3
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
3
cold shock, 4-day adult
2
heat shock, 4-day adult
3
Cadmium 50 mM 6 hrs, larvae L3
4
Cadmium 50 mM 12 hrs, larvae L3
2
Cadmium 50 mM 48 hrs, 4-day adult
2
Cadmium 100 mM 48 hrs, 4-day adult
2
Copper 0.5 mM 12 hrs, larvae L3
3
Copper 15 mM 48 hrs, 4-day adult
1
Zinc 5 mM 12 hrs, larvae L3
2
Zinc 4.5 mM 48 hrs, 4-day adult
3
Ethanol 2.5% 3 hrs, larvae L3
2
Ethanol 5% 3 hrs, larvae L3
3
Ethanol 10% 3 hrs, larvae L3
3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
2
Caffeine 25 mg/ml 48 hrs, 4-day adult
1
Paraquat 5 mM 48 hrs, 4-day adult
4
Paraquat 10 mM 48 hrs, 4-day adult
5
Rotenone 2 μg 12 hrs, larvae L3
4
Rotenone 8 μg 12 hrs, larvae L3
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
3
cold shock, 4-day adult
2
heat shock, 4-day adult
3
Cadmium 50 mM 6 hrs, larvae L3
4
Cadmium 50 mM 12 hrs, larvae L3
2
Cadmium 50 mM 48 hrs, 4-day adult
2
Cadmium 100 mM 48 hrs, 4-day adult
2
Copper 0.5 mM 12 hrs, larvae L3
3
Copper 15 mM 48 hrs, 4-day adult
1
Zinc 5 mM 12 hrs, larvae L3
2
Zinc 4.5 mM 48 hrs, 4-day adult
3
Ethanol 2.5% 3 hrs, larvae L3
2
Ethanol 5% 3 hrs, larvae L3
3
Ethanol 10% 3 hrs, larvae L3
3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
2
Caffeine 25 mg/ml 48 hrs, 4-day adult
1
Paraquat 5 mM 48 hrs, 4-day adult
4
Paraquat 10 mM 48 hrs, 4-day adult
5
Rotenone 2 μg 12 hrs, larvae L3
4
Rotenone 8 μg 12 hrs, larvae L3
5
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
3
cold shock, 4-day adult
2
heat shock, 4-day adult
3
Cadmium 50 mM 6 hrs, larvae L3
4
Cadmium 50 mM 12 hrs, larvae L3
2
Cadmium 50 mM 48 hrs, 4-day adult
2
Cadmium 100 mM 48 hrs, 4-day adult
2
Copper 0.5 mM 12 hrs, larvae L3
3
Copper 15 mM 48 hrs, 4-day adult
1
Zinc 5 mM 12 hrs, larvae L3
2
Zinc 4.5 mM 48 hrs, 4-day adult
3
Ethanol 2.5% 3 hrs, larvae L3
2
Ethanol 5% 3 hrs, larvae L3
3
Ethanol 10% 3 hrs, larvae L3
3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
2
Caffeine 25 mg/ml 48 hrs, 4-day adult
1
Paraquat 5 mM 48 hrs, 4-day adult
4
Paraquat 10 mM 48 hrs, 4-day adult
5
Rotenone 2 μg 12 hrs, larvae L3
4
Rotenone 8 μg 12 hrs, larvae L3
5
Expression Level Scale
Very low
Low
Moderate
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
3
cold shock, 4-day adult
2
heat shock, 4-day adult
3
Cadmium 50 mM 6 hrs, larvae L3
4
Cadmium 50 mM 12 hrs, larvae L3
2
Cadmium 50 mM 48 hrs, 4-day adult
2
Cadmium 100 mM 48 hrs, 4-day adult
2
Copper 0.5 mM 12 hrs, larvae L3
3
Copper 15 mM 48 hrs, 4-day adult
1
Zinc 5 mM 12 hrs, larvae L3
2
Zinc 4.5 mM 48 hrs, 4-day adult
3
Ethanol 2.5% 3 hrs, larvae L3
2
Ethanol 5% 3 hrs, larvae L3
3
Ethanol 10% 3 hrs, larvae L3
3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
2
Caffeine 25 mg/ml 48 hrs, 4-day adult
1
Paraquat 5 mM 48 hrs, 4-day adult
4
Paraquat 10 mM 48 hrs, 4-day adult
5
Rotenone 2 μg 12 hrs, larvae L3
4
Rotenone 8 μg 12 hrs, larvae L3
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
3
cold shock, 4-day adult
2
heat shock, 4-day adult
3
Cadmium 50 mM 6 hrs, larvae L3
4
Cadmium 50 mM 12 hrs, larvae L3
2
Cadmium 50 mM 48 hrs, 4-day adult
2
Cadmium 100 mM 48 hrs, 4-day adult
2
Copper 0.5 mM 12 hrs, larvae L3
3
Copper 15 mM 48 hrs, 4-day adult
1
Zinc 5 mM 12 hrs, larvae L3
2
Zinc 4.5 mM 48 hrs, 4-day adult
3
Ethanol 2.5% 3 hrs, larvae L3
2
Ethanol 5% 3 hrs, larvae L3
3
Ethanol 10% 3 hrs, larvae L3
3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
2
Caffeine 25 mg/ml 48 hrs, 4-day adult
1
Paraquat 5 mM 48 hrs, 4-day adult
4
Paraquat 10 mM 48 hrs, 4-day adult
5
Rotenone 2 μg 12 hrs, larvae L3
4
Rotenone 8 μg 12 hrs, larvae L3
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
3
cold shock, 4-day adult
2
heat shock, 4-day adult
3
Cadmium 50 mM 6 hrs, larvae L3
4
Cadmium 50 mM 12 hrs, larvae L3
2
Cadmium 50 mM 48 hrs, 4-day adult
2
Cadmium 100 mM 48 hrs, 4-day adult
2
Copper 0.5 mM 12 hrs, larvae L3
3
Copper 15 mM 48 hrs, 4-day adult
1
Zinc 5 mM 12 hrs, larvae L3
2
Zinc 4.5 mM 48 hrs, 4-day adult
3
Ethanol 2.5% 3 hrs, larvae L3
2
Ethanol 5% 3 hrs, larvae L3
3
Ethanol 10% 3 hrs, larvae L3
3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
4
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
2
Caffeine 25 mg/ml 48 hrs, 4-day adult
1
Paraquat 5 mM 48 hrs, 4-day adult
4
Paraquat 10 mM 48 hrs, 4-day adult
5
Rotenone 2 μg 12 hrs, larvae L3
4
Rotenone 8 μg 12 hrs, larvae L3
5
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 0 ) For All Classical Alleles Show Allele of
CG9220 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs
( 3 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Transgenic Constructs & Insertions
Transgenic Constructs Insertions Gene Ontology: Function, Process
& Cellular Component ( 5 unique terms ) Terms Based on
Experimental Evidence ( 0 terms ) Terms Based on Predictions or
Assertions ( 5 terms ) Molecular Function non-traceable author statement
non-traceable author statement
Biological Process non-traceable author statement
Cellular Component Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A comprehensive database of gene and protein interactions.
Orthologs
OrthoDB Orthologs (47)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG679FSG )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG6BP1KT )
Aedes aegypti
Yellow fever mosquito
Anopheles gambiae
Malaria mosquito
Culex quinquefasciatus
Southern house mosquito
Orthologs in non-Dipteran Insects
(EOG69P8TF )
Apis mellifera
Western honey bee
Amel\GB40162
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG024989
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH17212
Atta cephalotes
Leafcutter ant
Acep\ACEP27792
Atta cephalotes
Leafcutter ant
Acep\ACEP27790
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO18642
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL22165
Linepithema humile
Argentine ant
Lhum\LH21372
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB19976
Solenopsis invicta
Red fire ant
Sinv\SINV25934
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG6ZGMTB )
Ixodes scapularis
Deer tick
Orthologs in non-Arthropod Metazoa
(EOG6FBWKR )
Caenorhabditis elegans
Nematode
Strongylocentrotus purpuratus
Purple sea urchin
Strongylocentrotus purpuratus
Purple sea urchin
Xenopus tropicalis
Western clawed frog
Xenopus tropicalis
Western clawed frog
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Gallus gallus
Domestic chicken
Rattus norvegicus
Norway rat
Rattus norvegicus
Norway rat
Human Orthologs (2)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 3 )VDRC Genomic Clones ( 2 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 6 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for database merge of Additional comments Other Comments External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
Linkouts
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 1 )Reported As Symbol Synonym Name Synonym Secondary FlyBase
IDs References ( 10 )Research paper Luo et al., 2006, J. Biol. Chem. 281(14): 9393--9399Protein O-fucosyltransferase 2 adds O-fucose to thrombospondin type 1 repeats. [FBrf0194749] Supplementary material The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Review Wilson, 2002, Curr. Opin. Struct. Biol. 12(5): 569--577Glycosylation of proteins in plants and invertebrates. [FBrf0155642] Personal communication to FlyBase Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi CenterRNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi CenterRNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms.Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. (Computer file)Berkeley Drosophila Genome Project. (Computer file) [FBrf0125078] DNA/RNA sequence record Hwang, 2003.2.22, GenBank/EMBL/DDBJ: AY241926Drosophila melanogaster chondroitin synthase-like protein mRNA, complete cds. [FBrf0159412]