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Gene Dmel\CG8944

General Information
Symbol	Dmel\CG8944	Species	D. melanogaster
Name		Annotation symbol	CG8944
Feature type	protein_coding_gene	FlyBase ID	FBgn0030680
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	13E12-13E13	Sequence location	X:15,635,376..15,640,240 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG8944 (FBgn0030680). It is a protein_coding_gene from Drosophila melanogaster. An electronic pipeline based on InterPro domains suggests that it has the molecular function: zinc ion binding; nucleic acid binding. The biological processes in which it is involved are not known. 4 alleles are reported. The phenotype of these alleles is annotated with: mesothoracic tergum. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: MADF domain; Zinc finger, C2H2; Zinc finger, C2H2-like; Zinc finger, C2H2-type/integrase, DNA-binding. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system. Comments on Affy2 ProbeSet: ProbeSet 1636805_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG8944. Gene sequence location is X:15635376..15640240.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2011_10
FB2012_01	Sequence features BKN30332 HFA20128
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 13E12-13E13   Limits computationally determined from genome sequence between P{EP}EP1489 and P{EP}BEST:RE35685EP1581&P{EP}sdEP1088
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG8944 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.43
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG8944-RA FBtr0074200  NM_167460   4715   380 CG8944-RB FBtr0074201  NM_132837   4326   762
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG8944-PA   FBpp0073980   43.8   380   4.40     NP_727889   AAF48502 CG8944-PB   FBpp0073981   87.7   762   6.27     NP_573065   AAN09363
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • MADF domain (IPR006578) Zinc finger, C2H2 (IPR007087) Zinc finger, C2H2-like (IPR015880) Zinc finger, C2H2-type/integrase, DNA-binding (IPR013087)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA246938   AA390417   AA439194   AA440541   AA440694   AA816795   AA820557   AE014298 AAF48502   AE014298 AAN09363   AI061815   AI543402   AI543558   AI543568   AI544280   AI544290   AI546319   AW944660   AY095100 AAM11428   BI166974   BI170207   BI173244   BI214994   BI236751   BI367108   BI373465   BI481635   BI563365   BI574189   BI577202   BI578150   BT015275 AAT94504   CO189072   CO276619   CO276769   CO280158   CO303469   CO308549   CO315592   CO327520   CO329751   CO334000   CO344213   EC057924   EC063213   EC065681   EC066270   EC067391   EC067660   EC068009   EC197424   EC197698   EC213714   EC215208   EC220115   EC229835   EC232179   EC233752   EC247392   EC250378   EC255371   EC258554   GH941325   GH941629   GH942673   GH955998   GH956569   GH957999   GH961654   GH971315   GH971961   GH977245   GH980491   GH982285
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q8IR27 Q8T3I5 Q9VXQ6
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0030680    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0030680 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed within 00-18 hour embryonic stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0030680 expression level Developmental Stage   Expression Level embryo 00-02hr    3534 embryo 02-04hr    3387 embryo 04-06hr    1599 embryo 06-08hr    1609 embryo 08-10hr    1881 embryo 10-12hr    1338 embryo 12-14hr    1511 embryo 14-16hr    1600 embryo 16-18hr    1202 embryo 18-20hr    583 embryo 20-22hr    967 embryo 22-24hr    1053 larva L1    317 larva L2    219 larva L3 12hr old    203 larva L3 puffstage 1-2    221 larva L3 puffstage 3-6    394 larva L3 puffstage 7-9    512 white prepupae new    584 white prepupae 12hr    577 white prepupae 24hr    694 pupae 2d postWPP    458 pupae 3d postWPP    219 pupae 4d postWPP    240 adult male 01day    188 adult male 05day    213 adult male 30day    257 adult female 01day    970 adult female 05day    1925 adult female 30day    1862 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3534) embryo 02-04hr  (3387) embryo 04-06hr  (1599) embryo 06-08hr  (1609) embryo 08-10hr  (1881) embryo 10-12hr  (1338) embryo 12-14hr  (1511) embryo 14-16hr  (1600) embryo 16-18hr  (1202) embryo 18-20hr  (583) embryo 20-22hr  (967) embryo 22-24hr  (1053) larva L1  (317) larva L2  (219) larva L3 12hr old  (203) larva L3 puffstage 1-2  (221) larva L3 puffstage 3-6  (394) larva L3 puffstage 7-9  (512) white prepupae new  (584) white prepupae 12hr  (577) white prepupae 24hr  (694) pupae 2d postWPP  (458) pupae 3d postWPP  (219) pupae 4d postWPP  (240) adult male 01day  (188) adult male 05day  (213) adult male 30day  (257) adult female 01day  (970) adult female 05day  (1925) adult female 30day  (1862) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3534) embryo 02-04hr  (3387) embryo 04-06hr  (1599) embryo 06-08hr  (1609) embryo 08-10hr  (1881) embryo 10-12hr    1338 embryo 12-14hr  (1511) embryo 14-16hr  (1600) embryo 16-18hr    1202 embryo 18-20hr    583 embryo 20-22hr    967 embryo 22-24hr    1053 larva L1    317 larva L2    219 larva L3 12hr old    203 larva L3 puffstage 1-2    221 larva L3 puffstage 3-6    394 larva L3 puffstage 7-9    512 white prepupae new    584 white prepupae 12hr    577 white prepupae 24hr    694 pupae 2d postWPP    458 pupae 3d postWPP    219 pupae 4d postWPP    240 adult male 01day    188 adult male 05day    213 adult male 30day    257 adult female 01day    970 adult female 05day  (1925) adult female 30day  (1862) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3534 embryo 02-04hr    3387 embryo 04-06hr    1599 embryo 06-08hr    1609 embryo 08-10hr    1881 embryo 10-12hr    1338 embryo 12-14hr    1511 embryo 14-16hr    1600 embryo 16-18hr    1202 embryo 18-20hr    583 embryo 20-22hr    967 embryo 22-24hr    1053 larva L1    317 larva L2    219 larva L3 12hr old    203 larva L3 puffstage 1-2    221 larva L3 puffstage 3-6    394 larva L3 puffstage 7-9    512 white prepupae new    584 white prepupae 12hr    577 white prepupae 24hr    694 pupae 2d postWPP    458 pupae 3d postWPP    219 pupae 4d postWPP    240 adult male 01day    188 adult male 05day    213 adult male 30day    257 adult female 01day    970 adult female 05day    1925 adult female 30day    1862 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3534 embryo 02-04hr    3387 embryo 04-06hr    1599 embryo 06-08hr    1609 embryo 08-10hr    1881 embryo 10-12hr    1338 embryo 12-14hr    1511 embryo 14-16hr    1600 embryo 16-18hr    1202 embryo 18-20hr    583 embryo 20-22hr    967 embryo 22-24hr    1053 larva L1    317 larva L2    219 larva L3 12hr old    203 larva L3 puffstage 1-2    221 larva L3 puffstage 3-6    394 larva L3 puffstage 7-9    512 white prepupae new    584 white prepupae 12hr    577 white prepupae 24hr    694 pupae 2d postWPP    458 pupae 3d postWPP    219 pupae 4d postWPP    240 adult male 01day    188 adult male 05day    213 adult male 30day    257 adult female 01day    970 adult female 05day    1925 adult female 30day    1862 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0030680 expression level Developmental Stage   Expression Level embryo 00-02hr    3534 embryo 02-04hr    3387 embryo 04-06hr    1599 embryo 06-08hr    1609 embryo 08-10hr    1881 embryo 10-12hr    1338 embryo 12-14hr    1511 embryo 14-16hr    1600 embryo 16-18hr    1202 embryo 18-20hr    583 embryo 20-22hr    967 embryo 22-24hr    1053 larva L1    317 larva L2    219 larva L3 12hr old    203 larva L3 puffstage 1-2    221 larva L3 puffstage 3-6    394 larva L3 puffstage 7-9    512 white prepupae new    584 white prepupae 12hr    577 white prepupae 24hr    694 pupae 2d postWPP    458 pupae 3d postWPP    219 pupae 4d postWPP    240 adult male 01day    188 adult male 05day    213 adult male 30day    257 adult female 01day    970 adult female 05day    1925 adult female 30day    1862 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3534) embryo 02-04hr  (3387) embryo 04-06hr  (1599) embryo 06-08hr  (1609) embryo 08-10hr  (1881) embryo 10-12hr  (1338) embryo 12-14hr  (1511) embryo 14-16hr  (1600) embryo 16-18hr  (1202) embryo 18-20hr  (583) embryo 20-22hr  (967) embryo 22-24hr  (1053) larva L1  (317) larva L2  (219) larva L3 12hr old  (203) larva L3 puffstage 1-2  (221) larva L3 puffstage 3-6  (394) larva L3 puffstage 7-9  (512) white prepupae new  (584) white prepupae 12hr  (577) white prepupae 24hr  (694) pupae 2d postWPP  (458) pupae 3d postWPP  (219) pupae 4d postWPP  (240) adult male 01day  (188) adult male 05day  (213) adult male 30day  (257) adult female 01day  (970) adult female 05day  (1925) adult female 30day  (1862) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3534) embryo 02-04hr  (3387) embryo 04-06hr  1599 embryo 06-08hr  1609 embryo 08-10hr  1881 embryo 10-12hr    1338 embryo 12-14hr  1511 embryo 14-16hr  1600 embryo 16-18hr    1202 embryo 18-20hr    583 embryo 20-22hr    967 embryo 22-24hr    1053 larva L1    317 larva L2    219 larva L3 12hr old    203 larva L3 puffstage 1-2    221 larva L3 puffstage 3-6    394 larva L3 puffstage 7-9    512 white prepupae new    584 white prepupae 12hr    577 white prepupae 24hr    694 pupae 2d postWPP    458 pupae 3d postWPP    219 pupae 4d postWPP    240 adult male 01day    188 adult male 05day    213 adult male 30day    257 adult female 01day    970 adult female 05day  1925 adult female 30day  1862 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3534 embryo 02-04hr    3387 embryo 04-06hr    1599 embryo 06-08hr    1609 embryo 08-10hr    1881 embryo 10-12hr    1338 embryo 12-14hr    1511 embryo 14-16hr    1600 embryo 16-18hr    1202 embryo 18-20hr    583 embryo 20-22hr    967 embryo 22-24hr    1053 larva L1    317 larva L2    219 larva L3 12hr old    203 larva L3 puffstage 1-2    221 larva L3 puffstage 3-6    394 larva L3 puffstage 7-9    512 white prepupae new    584 white prepupae 12hr    577 white prepupae 24hr    694 pupae 2d postWPP    458 pupae 3d postWPP    219 pupae 4d postWPP    240 adult male 01day    188 adult male 05day    213 adult male 30day    257 adult female 01day    970 adult female 05day    1925 adult female 30day    1862 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3534 embryo 02-04hr    3387 embryo 04-06hr    1599 embryo 06-08hr    1609 embryo 08-10hr    1881 embryo 10-12hr    1338 embryo 12-14hr    1511 embryo 14-16hr    1600 embryo 16-18hr    1202 embryo 18-20hr    583 embryo 20-22hr    967 embryo 22-24hr    1053 larva L1    317 larva L2    219 larva L3 12hr old    203 larva L3 puffstage 1-2    221 larva L3 puffstage 3-6    394 larva L3 puffstage 7-9    512 white prepupae new    584 white prepupae 12hr    577 white prepupae 24hr    694 pupae 2d postWPP    458 pupae 3d postWPP    219 pupae 4d postWPP    240 adult male 01day    188 adult male 05day    213 adult male 30day    257 adult female 01day    970 adult female 05day    1925 adult female 30day    1862 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0030680    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0030680 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval central nervous system. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0030680 expression level Tissue   Expression Level Larval Central Nervous System    148.05 Larval Midgut    26.3 Larval Hindgut    39.8 Larval Malpighian Tubules    29.6 Larval Fat Body    22.5 Larval Salivary Gland    43.7 Larval Trachea    89.3 Larval Carcass    27.675 Adult Head    29.6 Adult Eye    60.425 Adult Brain    78.3 Adult Thoracic-Abdominal Ganglion    54.3 Adult Crop    40.5 Adult Midgut    24.7 Adult Hindgut    40.8 Adult Malpighian Tubules    21.5 Adult Fat Body    31.5 Adult Salivary Gland    49.6 Adult Heart    34.85 Adult VirginFemale Spermatheca    38 Adult InseminatedFemale Spermatheca    45.1 Adult Ovary    84.9 Adult Testis    7.7 Adult Male Accessory Gland    32.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    148.05 Larval Midgut    26.3 Larval Hindgut    39.8 Larval Malpighian Tubules    29.6 Larval Fat Body    22.5 Larval Salivary Gland    43.7 Larval Trachea    89.3 Larval Carcass    27.675 Adult Head    29.6 Adult Eye    60.425 Adult Brain    78.3 Adult Thoracic-Abdominal Ganglion    54.3 Adult Crop    40.5 Adult Midgut    24.7 Adult Hindgut    40.8 Adult Malpighian Tubules    21.5 Adult Fat Body    31.5 Adult Salivary Gland    49.6 Adult Heart    34.85 Adult VirginFemale Spermatheca    38 Adult InseminatedFemale Spermatheca    45.1 Adult Ovary    84.9 Adult Testis    7.7 Adult Male Accessory Gland    32.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    148.05 Larval Midgut    26.3 Larval Hindgut    39.8 Larval Malpighian Tubules    29.6 Larval Fat Body    22.5 Larval Salivary Gland    43.7 Larval Trachea    89.3 Larval Carcass    27.675 Adult Head    29.6 Adult Eye    60.425 Adult Brain    78.3 Adult Thoracic-Abdominal Ganglion    54.3 Adult Crop    40.5 Adult Midgut    24.7 Adult Hindgut    40.8 Adult Malpighian Tubules    21.5 Adult Fat Body    31.5 Adult Salivary Gland    49.6 Adult Heart    34.85 Adult VirginFemale Spermatheca    38 Adult InseminatedFemale Spermatheca    45.1 Adult Ovary    84.9 Adult Testis    7.7 Adult Male Accessory Gland    32.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    148.05 Larval Midgut    26.3 Larval Hindgut    39.8 Larval Malpighian Tubules    29.6 Larval Fat Body    22.5 Larval Salivary Gland    43.7 Larval Trachea    89.3 Larval Carcass    27.675 Adult Head    29.6 Adult Eye    60.425 Adult Brain    78.3 Adult Thoracic-Abdominal Ganglion    54.3 Adult Crop    40.5 Adult Midgut    24.7 Adult Hindgut    40.8 Adult Malpighian Tubules    21.5 Adult Fat Body    31.5 Adult Salivary Gland    49.6 Adult Heart    34.85 Adult VirginFemale Spermatheca    38 Adult InseminatedFemale Spermatheca    45.1 Adult Ovary    84.9 Adult Testis    7.7 Adult Male Accessory Gland    32.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0030680 expression level Tissue   Expression Level Larval Central Nervous System    148.05 Larval Midgut    26.3 Larval Hindgut    39.8 Larval Malpighian Tubules    29.6 Larval Fat Body    22.5 Larval Salivary Gland    43.7 Larval Trachea    89.3 Larval Carcass    27.675 Adult Head    29.6 Adult Eye    60.425 Adult Brain    78.3 Adult Thoracic-Abdominal Ganglion    54.3 Adult Crop    40.5 Adult Midgut    24.7 Adult Hindgut    40.8 Adult Malpighian Tubules    21.5 Adult Fat Body    31.5 Adult Salivary Gland    49.6 Adult Heart    34.85 Adult VirginFemale Spermatheca    38 Adult InseminatedFemale Spermatheca    45.1 Adult Ovary    84.9 Adult Testis    7.7 Adult Male Accessory Gland    32.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    148.05 Larval Midgut    26.3 Larval Hindgut    39.8 Larval Malpighian Tubules    29.6 Larval Fat Body    22.5 Larval Salivary Gland    43.7 Larval Trachea    89.3 Larval Carcass    27.675 Adult Head    29.6 Adult Eye    60.425 Adult Brain    78.3 Adult Thoracic-Abdominal Ganglion    54.3 Adult Crop    40.5 Adult Midgut    24.7 Adult Hindgut    40.8 Adult Malpighian Tubules    21.5 Adult Fat Body    31.5 Adult Salivary Gland    49.6 Adult Heart    34.85 Adult VirginFemale Spermatheca    38 Adult InseminatedFemale Spermatheca    45.1 Adult Ovary    84.9 Adult Testis    7.7 Adult Male Accessory Gland    32.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    148.05 Larval Midgut    26.3 Larval Hindgut    39.8 Larval Malpighian Tubules    29.6 Larval Fat Body    22.5 Larval Salivary Gland    43.7 Larval Trachea    89.3 Larval Carcass    27.675 Adult Head    29.6 Adult Eye    60.425 Adult Brain    78.3 Adult Thoracic-Abdominal Ganglion    54.3 Adult Crop    40.5 Adult Midgut    24.7 Adult Hindgut    40.8 Adult Malpighian Tubules    21.5 Adult Fat Body    31.5 Adult Salivary Gland    49.6 Adult Heart    34.85 Adult VirginFemale Spermatheca    38 Adult InseminatedFemale Spermatheca    45.1 Adult Ovary    84.9 Adult Testis    7.7 Adult Male Accessory Gland    32.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    148.05 Larval Midgut    26.3 Larval Hindgut    39.8 Larval Malpighian Tubules    29.6 Larval Fat Body    22.5 Larval Salivary Gland    43.7 Larval Trachea    89.3 Larval Carcass    27.675 Adult Head    29.6 Adult Eye    60.425 Adult Brain    78.3 Adult Thoracic-Abdominal Ganglion    54.3 Adult Crop    40.5 Adult Midgut    24.7 Adult Hindgut    40.8 Adult Malpighian Tubules    21.5 Adult Fat Body    31.5 Adult Salivary Gland    49.6 Adult Heart    34.85 Adult VirginFemale Spermatheca    38 Adult InseminatedFemale Spermatheca    45.1 Adult Ovary    84.9 Adult Testis    7.7 Adult Male Accessory Gland    32.6 Adult Carcass no informative data Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass no informative data FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    29.6   NA  Eye    60.425   NA  Brain    78.3   148.05  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    54.3   NA  Crop    40.5   26.3  Midgut    24.7   39.8  Hindgut    40.8   29.6  Malpighian Tubules    21.5   22.5  Fat Body    31.5   43.7  Salivary Gland    49.6   NA  Heart    34.85   89.3  Trachea    NA   NA  VirginFemale Spermatheca    38   NA  InseminatedFemale Spermatheca    45.1   NA  Ovary    84.9   NA  Testis    7.7   NA  Male Accessory Gland    32.6   27.675  Carcass    no informative data modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_17
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030680 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8944-RA
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG8944GD14076 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 CG8944GD14076 Phenotype manifest in Allele mesothoracic tergum, with Scer\GAL4pnr-MD237 CG8944GD14076
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG8944 Class Mutagen Stocks Known lesion CG8944G1578 P-element activity 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG8944 Class Mutagen Stocks Known lesion CG8944GD14076 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG8944JF02215 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG8944GD17111 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Disrupted in	Df(1)Exel6250 (Ryder, 2004.4.26)
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD14076} NA P{GD17111} NA P{TRiP.JF02215} NA
Insertions
	Type of insertions Name Expression data insertion of mobile activating element P{EP}CG8944G1578 NA
Gene Ontology: Function, Process & Cellular Component ( 3 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 3 terms )
Molecular Function
CV term Evidence References
nucleic acid binding inferred from electronic annotation with InterPro:IPR013087 (FlyBase Curators et al., 2004-) zinc ion binding inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880 (FlyBase Curators et al., 2004-)
Biological Process ( 0 terms)
Cellular Component
CV term Evidence References
intracellular inferred from electronic annotation with InterPro:IPR007087, InterPro:IPR015880 (FlyBase Curators et al., 2004-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG8944 allele Gene References
External Data
Linkouts	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030680 DroID - A comprehensive database of gene and protein interactions. • FBgn0030680
Orthologs
Genome-wide drosophilid orthologs	Dana\GF19447 Dere\GG19376 Dgri\GH24798 Dmoj\GI15951 Dper\GL14814 Dpse\GA21424 Dsec\GM22530 Dsim\GD15780 Dvir\GJ14857 Dwil\GK25298 Dyak\GE16024
Curated drosophilid orthologs	Dpse\GA21424
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • XP_001943359.1 Acyrthosiphon pisum (pea aphid) PP26942 Pristionchus pacificus (nematode) YLR375W Saccharomyces cerevisiae (budding yeast) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0233576 FBgn0227257 FBgn0202061 FBgn0187440 FBgn0177400 FBgn0081411 FBgn0152418 FBgn0138700 FBgn0132253 FBgn0111580 FBgn0096456
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	32594 w* P{EP}CG8944G1578 31925 y1 v1; P{TRiP.JF02215}attP2
VDRC	v36066 w1118; P{GD14076}v36066 v36067 w1118; P{GD14076}v36067/TM3
Genomic Clones ( 2 )
	BACR22H11 BACR25C18 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 70 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD18191 SD10776
Other clones	DPiM_LD18191
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	LD05947 LD09330 LD10372 LD13684 LD15351 LD15556 LD24351 LD34952 LD47869 RE07236 RE11589 RE16027 RE21171 RE32859 RE52788 RE60752 RE64222 RE70854 RE71974 RH22921 RH33990 SD10141 SD10352 SD10364 SD10788
Other clones	647 884 39333 64584 77415 103358 121665 155774 158986 175549 191378 214403.33 214413.32 272850 283310 CK01.53B.H9 CK01.55C.A4 CK01.127B.D8 CK01.133A.A6 EK042931 EK121614 EK122020 EK152760 EK241631 EK258661 EK261946 EK293728 EK308555 EP07426 EP18853 RP004045277 RP004076013 RP004087019 RP004223419 RP004240301 RP004258474 RP004264060 RP004268934 RP004297888 RP004404990 RP004414474 RP004532327
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030680 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32517
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132837 NM_167460 RefSeq (Proteins) • NP_573065 NP_727889 DDBJ / EMBL / GenBank • AAF48502 AAM11428 AAN09363 AAT94504 AI544280 AW944660 AY095100 BT015275 Entrez Gene - A searchable database of RefSeq genes. • 32517 UniProtKB/TrEMBL • Q8IR27 Q8T3I5 Q9VXQ6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • MADF domain (IPR006578) Zinc finger, C2H2 (IPR007087) Zinc finger, C2H2-like (IPR015880) Zinc finger, C2H2-type/integrase, DNA-binding (IPR013087)
Linkouts
	DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030680 DroID - A comprehensive database of gene and protein interactions. • FBgn0030680 DRSC - Results from RNAi screens. • FBgn0030680 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030680 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8944-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030680 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32517 InParanoid A subset of ortholog calls from InParanoid. • XP_001943359.1 Acyrthosiphon pisum (pea aphid) PP26942 Pristionchus pacificus (nematode) YLR375W Saccharomyces cerevisiae (budding yeast) modMine - Data generated by the modENCODE project. • FBgn0030680 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • FBgn0233576 FBgn0227257 FBgn0202061 FBgn0187440 FBgn0177400 FBgn0081411 FBgn0152418 FBgn0138700 FBgn0132253 FBgn0111580 FBgn0096456
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG8944 (Perkins et al., 2009)
Name Synonym
Secondary FlyBase IDs
References ( 14 )
Research paper	Stark et al., 2003, PLoS Biol. 1(3): 397--409 Identification of Drosophila microRNA targets. [FBrf0167987]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Dietzl et al., 2007, Nature 448(7150): Supplementary Table 1. [FBrf0202579]
Personal communication to FlyBase	Bellen, 2010.10.18, BDGP_2010_1022.GenExel.xml BDGP_2010_1022.GenExel.xml [FBrf0212107] Perkins et al., 2009, Update to TRiP stock collection. Update to TRiP stock collection. [FBrf0208864] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Ryder, 2004.4.26, Exelixis CG deletion data. Exelixis CG deletion data. [FBrf0184335]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
Curated genome annotation	Lei, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126680]