Gene Dmel\CG15602

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General Information

Symbol

Dmel\CG15602

Species

D. melanogaster

Name

Annotation symbol

CG15602

Feature type

protein_coding_gene

FlyBase ID

FBgn0030694

Gene Model Status

Current

Stock availability

3 publicly available

Genomic Location

Chromosome (arm)

Recombination map

Cytogenetic map

13F1-13F1

Sequence location

X:15,693,459..15,694,994 [+]

Genomic Maps

Select View:

Summary Information

Automatically generated summary

See sections below for more information

This gene is referred to in FlyBase by the symbol Dmel\CG15602 (FBgn0030694). It is a protein_coding_gene from Drosophila melanogaster. Its molecular function is unknown. The biological processes in which it is involved are not known. 3 alleles are reported. No phenotypic data is available. It has 2 annotated transcripts and 2 annotated polypeptides. Protein features are: Zinc finger, FYVE-related; Zinc finger, FYVE/PHD-type; Zinc finger, RING/FYVE/PHD-type. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed during late larval stages. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult ovary, adult male reproductive system, larval/adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1630115_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG15602. Gene sequence location is X:15693459..15694994.

User Contributed Data

Beta version, feedback welcome

Recent Updates

Description

What does this section display?

This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms).

What does this section not display?

This section does not currently display links that were removed or gene model changes.

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FB2013_03

FB2013_02

All updates

Click here to see a list of all updates to this record from FB2010_08 and on.

Detailed Mapping Data

FlyBase Computed Cytological Location

Cytogenetic map

Evidence for location

13F1-13F1

Limits computationally determined from genome sequence between P{EP}EP1489 and P{EP}BEST:RE35685^EP1581&P{EP}sd^EP1088

Experimentally Determined Cytological Location

Cytogenetic map

Notes

References

Experimentally Determined Recombination Data

Location

Left of (cM)

Right of (cM)

Notes

Gene Model & Products

Please see the GBrowse view of Dmel\CG15602 for information on other features

To submit a correction to a gene model please use the Contact FlyBase form

Comments on Gene Model

Gene model reviewed during 5.42

Gene model reviewed during 5.43

Gene model reviewed during 5.50

Transcript Data

Annotated Transcripts

Name

FlyBase ID

RefSeq ID

Length (nt)

Associated CDS (aa)

CG15602-RA

FBtr0074097

NM_132849

1172

342

CG15602-RB

FBtr0340114

1342

342

Additional Transcript Data & Comments

Reported size (kB)

Comments

External Data

Crossreferences

Polypeptide Data

Annotated Polypeptides

Name

FlyBase ID

Predicted MW (kDa)

Length (aa)

Theoretical pI

RefSeq ID

GenBank protein

CG15602-PA

FBpp0073912

38.6

342

4.72

NP_573077

AAF48518

CG15602-PB

FBpp0309109

38.6

342

4.72

Additional Polypeptide Data & Comments

Reported size (kDa)

Comments

External Data

Linkouts

Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Zinc finger, RING/FYVE/PHD-type (IPR013083)

Zinc finger, FYVE-related (IPR017455)

Zinc finger, FYVE/PHD-type (IPR011011)

Sequences Consistent with the Gene Model

DDBJ /
EMBL /
GenBank

DNA sequence

Protein sequence

Name

Q4QQ70

Mapped Features

Mapped Features have been reorganized, please see this article for details.

Additional mapped features and mutations can be found on GBrowse or related reports.

Type

Symbol & Location

Additional Notes

References

External Data

Linkouts

Crossreferences

Expression Data

Transcript Expression

Additional Descriptive Data

Marker for

Subcellular Localization

CV Term

Polypeptide Expression

Additional Descriptive Data

Marker for

Subcellular Localization (GO Cellular Component)

CV term

Evidence

References

Expression Deduced from Reporters

High-Throughput Expression Data

Associated Tools

Reference

See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.

FlyAtlas Anatomy Microarray

FlyAtlas Anatomical Expression Data

(FlyAtlas-RNA.adult)

(FlyAtlas-RNA.larva)

	Styles
	Linear
	Logarithmic
	Heatmap
	Back-to-back
	Scales
	gene max expression
	Moderate expression bin max
	High level expression bin max
	Very high expression bin max

Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult tissues/organs expressed at moderate levels. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval/adult fat body, larval/adult salivary gland, larval trachea, adult ovary, adult male reproductive system, larval/adult carcass.
[download data (TSV)]

Guide to FlyAtlas expression level colors
	No expression (0 - 9.999)
	Low expression (10 - 99.999)
	Moderate expression (100 - 499.999)
	High level expression (500 - 999.999)
	Very high expression (>999.999)

Linear, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		133.825
Larval Midgut		147.7
Larval Hindgut		151.3
Larval Malpighian Tubules		340.6
Larval Fat Body		179.7
Larval Salivary Gland		199
Larval Trachea		131.05
Larval Carcass		104.775
Adult Head		169.4
Adult Eye		213.45
Adult Brain		207.6
Adult Thoracic-Abdominal Ganglion		204.3
Adult Crop		215.4
Adult Midgut		139.4
Adult Hindgut		174.1
Adult Malpighian Tubules		121.2
Adult Fat Body		129.8
Adult Salivary Gland		137
Adult Heart		127.125
Adult VirginFemale Spermatheca		76.5
Adult InseminatedFemale Spermatheca		71.1
Adult Ovary		307.3
Adult Testis		145.3
Adult Male Accessory Gland		105.8
Adult Carcass		129.4
Expression Level Scale		None Low Moderate

Linear, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		133.825
Larval Midgut		147.7
Larval Hindgut		151.3
Larval Malpighian Tubules		340.6
Larval Fat Body		179.7
Larval Salivary Gland		199
Larval Trachea		131.05
Larval Carcass		104.775
Adult Head		169.4
Adult Eye		213.45
Adult Brain		207.6
Adult Thoracic-Abdominal Ganglion		204.3
Adult Crop		215.4
Adult Midgut		139.4
Adult Hindgut		174.1
Adult Malpighian Tubules		121.2
Adult Fat Body		129.8
Adult Salivary Gland		137
Adult Heart		127.125
Adult VirginFemale Spermatheca		76.5
Adult InseminatedFemale Spermatheca		71.1
Adult Ovary		307.3
Adult Testis		145.3
Adult Male Accessory Gland		105.8
Adult Carcass		129.4
Expression Level Scale		None Low Moderate High

Linear, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		133.825
Larval Midgut		147.7
Larval Hindgut		151.3
Larval Malpighian Tubules		340.6
Larval Fat Body		179.7
Larval Salivary Gland		199
Larval Trachea		131.05
Larval Carcass		104.775
Adult Head		169.4
Adult Eye		213.45
Adult Brain		207.6
Adult Thoracic-Abdominal Ganglion		204.3
Adult Crop		215.4
Adult Midgut		139.4
Adult Hindgut		174.1
Adult Malpighian Tubules		121.2
Adult Fat Body		129.8
Adult Salivary Gland		137
Adult Heart		127.125
Adult VirginFemale Spermatheca		76.5
Adult InseminatedFemale Spermatheca		71.1
Adult Ovary		307.3
Adult Testis		145.3
Adult Male Accessory Gland		105.8
Adult Carcass		129.4
Expression Level Scale		None Low Moderate High Very high

Linear, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		133.825
Larval Midgut		147.7
Larval Hindgut		151.3
Larval Malpighian Tubules		340.6
Larval Fat Body		179.7
Larval Salivary Gland		199
Larval Trachea		131.05
Larval Carcass		104.775
Adult Head		169.4
Adult Eye		213.45
Adult Brain		207.6
Adult Thoracic-Abdominal Ganglion		204.3
Adult Crop		215.4
Adult Midgut		139.4
Adult Hindgut		174.1
Adult Malpighian Tubules		121.2
Adult Fat Body		129.8
Adult Salivary Gland		137
Adult Heart		127.125
Adult VirginFemale Spermatheca		76.5
Adult InseminatedFemale Spermatheca		71.1
Adult Ovary		307.3
Adult Testis		145.3
Adult Male Accessory Gland		105.8
Adult Carcass		129.4
Expression Level Scale		Very high

log, scaled to maximum expression level
Tissue		Expression Level
Larval Central Nervous System		133.825
Larval Midgut		147.7
Larval Hindgut		151.3
Larval Malpighian Tubules		340.6
Larval Fat Body		179.7
Larval Salivary Gland		199
Larval Trachea		131.05
Larval Carcass		104.775
Adult Head		169.4
Adult Eye		213.45
Adult Brain		207.6
Adult Thoracic-Abdominal Ganglion		204.3
Adult Crop		215.4
Adult Midgut		139.4
Adult Hindgut		174.1
Adult Malpighian Tubules		121.2
Adult Fat Body		129.8
Adult Salivary Gland		137
Adult Heart		127.125
Adult VirginFemale Spermatheca		76.5
Adult InseminatedFemale Spermatheca		71.1
Adult Ovary		307.3
Adult Testis		145.3
Adult Male Accessory Gland		105.8
Adult Carcass		129.4
Expression Level Scale		None Low Moderate High

log, scaled to Moderate expression
Tissue		Expression Level
Larval Central Nervous System		133.825
Larval Midgut		147.7
Larval Hindgut		151.3
Larval Malpighian Tubules		340.6
Larval Fat Body		179.7
Larval Salivary Gland		199
Larval Trachea		131.05
Larval Carcass		104.775
Adult Head		169.4
Adult Eye		213.45
Adult Brain		207.6
Adult Thoracic-Abdominal Ganglion		204.3
Adult Crop		215.4
Adult Midgut		139.4
Adult Hindgut		174.1
Adult Malpighian Tubules		121.2
Adult Fat Body		129.8
Adult Salivary Gland		137
Adult Heart		127.125
Adult VirginFemale Spermatheca		76.5
Adult InseminatedFemale Spermatheca		71.1
Adult Ovary		307.3
Adult Testis		145.3
Adult Male Accessory Gland		105.8
Adult Carcass		129.4
Expression Level Scale		None Low Moderate High

log, scaled to High level expression
Tissue		Expression Level
Larval Central Nervous System		133.825
Larval Midgut		147.7
Larval Hindgut		151.3
Larval Malpighian Tubules		340.6
Larval Fat Body		179.7
Larval Salivary Gland		199
Larval Trachea		131.05
Larval Carcass		104.775
Adult Head		169.4
Adult Eye		213.45
Adult Brain		207.6
Adult Thoracic-Abdominal Ganglion		204.3
Adult Crop		215.4
Adult Midgut		139.4
Adult Hindgut		174.1
Adult Malpighian Tubules		121.2
Adult Fat Body		129.8
Adult Salivary Gland		137
Adult Heart		127.125
Adult VirginFemale Spermatheca		76.5
Adult InseminatedFemale Spermatheca		71.1
Adult Ovary		307.3
Adult Testis		145.3
Adult Male Accessory Gland		105.8
Adult Carcass		129.4
Expression Level Scale		None Low Moderate High Very high

log, scaled to Very high expression
Tissue		Expression Level
Larval Central Nervous System		133.825
Larval Midgut		147.7
Larval Hindgut		151.3
Larval Malpighian Tubules		340.6
Larval Fat Body		179.7
Larval Salivary Gland		199
Larval Trachea		131.05
Larval Carcass		104.775
Adult Head		169.4
Adult Eye		213.45
Adult Brain		207.6
Adult Thoracic-Abdominal Ganglion		204.3
Adult Crop		215.4
Adult Midgut		139.4
Adult Hindgut		174.1
Adult Malpighian Tubules		121.2
Adult Fat Body		129.8
Adult Salivary Gland		137
Adult Heart		127.125
Adult VirginFemale Spermatheca		76.5
Adult InseminatedFemale Spermatheca		71.1
Adult Ovary		307.3
Adult Testis		145.3
Adult Male Accessory Gland		105.8
Adult Carcass		129.4
Expression Level Scale		None Low Moderate High Very high

Heatmap
Tissue		Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass

FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level	Tissue	Adult Expression Level
NA	Head	169.4
NA	Eye	213.45
NA	Brain	207.6
133.825	Central Nervous System	NA
NA	Thoracic-Abdominal Ganglion	204.3
NA	Crop	215.4
147.7	Midgut	139.4
151.3	Hindgut	174.1
340.6	Malpighian Tubules	121.2
179.7	Fat Body	129.8
199	Salivary Gland	137
NA	Heart	127.125
131.05	Trachea	NA
NA	VirginFemale Spermatheca	76.5
NA	InseminatedFemale Spermatheca	71.1
NA	Ovary	307.3
NA	Testis	145.3
NA	Male Accessory Gland	105.8
104.775	Carcass	129.4

FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)

modENCODE Anatomy RNA-Seq

modENCODE Tissue Expression Data

(modENCODE_mRNA-Seq_tissues)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		20
central nervous system, larvae L3		15
central nervous system, pupae P8		13
head, virgin 1-day female		12
head, virgin 4-day female		14
head, virgin 20-day female		13
head, mated 1-day female		13
head, mated 4-day female		12
head, mated 20-day female		12
head, mated 1-day male		23
head, mated 4-day male		18
head, mated 20-day male		25
salivary gland, larvae L3 wandering		12
salivary gland, white prepupae		29
digestive system, larvae L3 wandering		33
digestive system, 1-day adult		10
digestive system, 4-day adult		11
digestive system, 20-day adult		10
fat body, larvae L3 wandering		5
fat body, white prepupae		14
fat body, pupae P8		29
carcass, larvae L3 wandering		18
carcass, 1-day adult		9
carcass, 4-day adult		9
carcass, 20-day adult		13
ovary, virgin 4-day female		36
ovary, mated 4-day female		27
testis, mated 4-day male		23
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		20
central nervous system, larvae L3		15
central nervous system, pupae P8		13
head, virgin 1-day female		12
head, virgin 4-day female		14
head, virgin 20-day female		13
head, mated 1-day female		13
head, mated 4-day female		12
head, mated 20-day female		12
head, mated 1-day male		23
head, mated 4-day male		18
head, mated 20-day male		25
salivary gland, larvae L3 wandering		12
salivary gland, white prepupae		(29)
digestive system, larvae L3 wandering		(33)
digestive system, 1-day adult		10
digestive system, 4-day adult		11
digestive system, 20-day adult		10
fat body, larvae L3 wandering		5
fat body, white prepupae		14
fat body, pupae P8		(29)
carcass, larvae L3 wandering		18
carcass, 1-day adult		9
carcass, 4-day adult		9
carcass, 20-day adult		13
ovary, virgin 4-day female		(36)
ovary, mated 4-day female		(27)
testis, mated 4-day male		23
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		20
central nervous system, larvae L3		15
central nervous system, pupae P8		13
head, virgin 1-day female		12
head, virgin 4-day female		14
head, virgin 20-day female		13
head, mated 1-day female		13
head, mated 4-day female		12
head, mated 20-day female		12
head, mated 1-day male		23
head, mated 4-day male		18
head, mated 20-day male		25
salivary gland, larvae L3 wandering		12
salivary gland, white prepupae		29
digestive system, larvae L3 wandering		33
digestive system, 1-day adult		10
digestive system, 4-day adult		11
digestive system, 20-day adult		10
fat body, larvae L3 wandering		5
fat body, white prepupae		14
fat body, pupae P8		29
carcass, larvae L3 wandering		18
carcass, 1-day adult		9
carcass, 4-day adult		9
carcass, 20-day adult		13
ovary, virgin 4-day female		36
ovary, mated 4-day female		27
testis, mated 4-day male		23
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		20
central nervous system, larvae L3		15
central nervous system, pupae P8		13
head, virgin 1-day female		12
head, virgin 4-day female		14
head, virgin 20-day female		13
head, mated 1-day female		13
head, mated 4-day female		12
head, mated 20-day female		12
head, mated 1-day male		23
head, mated 4-day male		18
head, mated 20-day male		25
salivary gland, larvae L3 wandering		12
salivary gland, white prepupae		29
digestive system, larvae L3 wandering		33
digestive system, 1-day adult		10
digestive system, 4-day adult		11
digestive system, 20-day adult		10
fat body, larvae L3 wandering		5
fat body, white prepupae		14
fat body, pupae P8		29
carcass, larvae L3 wandering		18
carcass, 1-day adult		9
carcass, 4-day adult		9
carcass, 20-day adult		13
ovary, virgin 4-day female		36
ovary, mated 4-day female		27
testis, mated 4-day male		23
accessory gland, mated 4-day male		6
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Tissue		Expression Level
imaginal disc, larvae L3 wandering		20
central nervous system, larvae L3		15
central nervous system, pupae P8		13
head, virgin 1-day female		12
head, virgin 4-day female		14
head, virgin 20-day female		13
head, mated 1-day female		13
head, mated 4-day female		12
head, mated 20-day female		12
head, mated 1-day male		23
head, mated 4-day male		18
head, mated 20-day male		25
salivary gland, larvae L3 wandering		12
salivary gland, white prepupae		29
digestive system, larvae L3 wandering		33
digestive system, 1-day adult		10
digestive system, 4-day adult		11
digestive system, 20-day adult		10
fat body, larvae L3 wandering		5
fat body, white prepupae		14
fat body, pupae P8		29
carcass, larvae L3 wandering		18
carcass, 1-day adult		9
carcass, 4-day adult		9
carcass, 20-day adult		13
ovary, virgin 4-day female		36
ovary, mated 4-day female		27
testis, mated 4-day male		23
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high High

log, scaled to Moderate expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		20
central nervous system, larvae L3		15
central nervous system, pupae P8		13
head, virgin 1-day female		12
head, virgin 4-day female		14
head, virgin 20-day female		13
head, mated 1-day female		13
head, mated 4-day female		12
head, mated 20-day female		12
head, mated 1-day male		23
head, mated 4-day male		18
head, mated 20-day male		25
salivary gland, larvae L3 wandering		12
salivary gland, white prepupae		29
digestive system, larvae L3 wandering		(33)
digestive system, 1-day adult		10
digestive system, 4-day adult		11
digestive system, 20-day adult		10
fat body, larvae L3 wandering		5
fat body, white prepupae		14
fat body, pupae P8		29
carcass, larvae L3 wandering		18
carcass, 1-day adult		9
carcass, 4-day adult		9
carcass, 20-day adult		13
ovary, virgin 4-day female		(36)
ovary, mated 4-day female		27
testis, mated 4-day male		23
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		20
central nervous system, larvae L3		15
central nervous system, pupae P8		13
head, virgin 1-day female		12
head, virgin 4-day female		14
head, virgin 20-day female		13
head, mated 1-day female		13
head, mated 4-day female		12
head, mated 20-day female		12
head, mated 1-day male		23
head, mated 4-day male		18
head, mated 20-day male		25
salivary gland, larvae L3 wandering		12
salivary gland, white prepupae		29
digestive system, larvae L3 wandering		33
digestive system, 1-day adult		10
digestive system, 4-day adult		11
digestive system, 20-day adult		10
fat body, larvae L3 wandering		5
fat body, white prepupae		14
fat body, pupae P8		29
carcass, larvae L3 wandering		18
carcass, 1-day adult		9
carcass, 4-day adult		9
carcass, 20-day adult		13
ovary, virgin 4-day female		36
ovary, mated 4-day female		27
testis, mated 4-day male		23
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Tissue		Expression Level
imaginal disc, larvae L3 wandering		20
central nervous system, larvae L3		15
central nervous system, pupae P8		13
head, virgin 1-day female		12
head, virgin 4-day female		14
head, virgin 20-day female		13
head, mated 1-day female		13
head, mated 4-day female		12
head, mated 20-day female		12
head, mated 1-day male		23
head, mated 4-day male		18
head, mated 20-day male		25
salivary gland, larvae L3 wandering		12
salivary gland, white prepupae		29
digestive system, larvae L3 wandering		33
digestive system, 1-day adult		10
digestive system, 4-day adult		11
digestive system, 20-day adult		10
fat body, larvae L3 wandering		5
fat body, white prepupae		14
fat body, pupae P8		29
carcass, larvae L3 wandering		18
carcass, 1-day adult		9
carcass, 4-day adult		9
carcass, 20-day adult		13
ovary, virgin 4-day female		36
ovary, mated 4-day female		27
testis, mated 4-day male		23
accessory gland, mated 4-day male		6
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Tissue		Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male

modENCODE Development RNA-Seq

modENCODE Temporal Expression Data

(modENCODE_mRNA-Seq_U)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of moderately high expression to a trough of low expression. Peak expression observed during late larval stages.
[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		14
embryo 02-04hr		3
embryo 04-06hr		6
embryo 06-08hr		9
embryo 08-10hr		9
embryo 10-12hr		8
embryo 12-14hr		9
embryo 14-16hr		5
embryo 16-18hr		6
embryo 18-20hr		6
embryo 20-22hr		5
embryo 22-24hr		6
larva L1		5
larva L2		6
larva L3 12hr old		4
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		17
white prepupae new		15
white prepupae 12hr		15
white prepupae 24hr		13
pupae 2d postWPP		12
pupae 3d postWPP		8
pupae 4d postWPP		5
adult male 01day		10
adult male 05day		11
adult male 30day		11
adult female 01day		8
adult female 05day		15
adult female 30day		15
Expression Level Scale		Very low Low Moderate

Linear, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		14
embryo 02-04hr		3
embryo 04-06hr		6
embryo 06-08hr		9
embryo 08-10hr		9
embryo 10-12hr		8
embryo 12-14hr		9
embryo 14-16hr		5
embryo 16-18hr		6
embryo 18-20hr		6
embryo 20-22hr		5
embryo 22-24hr		6
larva L1		5
larva L2		6
larva L3 12hr old		4
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		17
white prepupae new		15
white prepupae 12hr		15
white prepupae 24hr		13
pupae 2d postWPP		12
pupae 3d postWPP		8
pupae 4d postWPP		5
adult male 01day		10
adult male 05day		11
adult male 30day		11
adult female 01day		8
adult female 05day		15
adult female 30day		15
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		14
embryo 02-04hr		3
embryo 04-06hr		6
embryo 06-08hr		9
embryo 08-10hr		9
embryo 10-12hr		8
embryo 12-14hr		9
embryo 14-16hr		5
embryo 16-18hr		6
embryo 18-20hr		6
embryo 20-22hr		5
embryo 22-24hr		6
larva L1		5
larva L2		6
larva L3 12hr old		4
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		17
white prepupae new		15
white prepupae 12hr		15
white prepupae 24hr		13
pupae 2d postWPP		12
pupae 3d postWPP		8
pupae 4d postWPP		5
adult male 01day		10
adult male 05day		11
adult male 30day		11
adult female 01day		8
adult female 05day		15
adult female 30day		15
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		14
embryo 02-04hr		3
embryo 04-06hr		6
embryo 06-08hr		9
embryo 08-10hr		9
embryo 10-12hr		8
embryo 12-14hr		9
embryo 14-16hr		5
embryo 16-18hr		6
embryo 18-20hr		6
embryo 20-22hr		5
embryo 22-24hr		6
larva L1		5
larva L2		6
larva L3 12hr old		4
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		17
white prepupae new		15
white prepupae 12hr		15
white prepupae 24hr		13
pupae 2d postWPP		12
pupae 3d postWPP		8
pupae 4d postWPP		5
adult male 01day		10
adult male 05day		11
adult male 30day		11
adult female 01day		8
adult female 05day		15
adult female 30day		15
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Developmental Stage		Expression Level
embryo 00-02hr		14
embryo 02-04hr		3
embryo 04-06hr		6
embryo 06-08hr		9
embryo 08-10hr		9
embryo 10-12hr		8
embryo 12-14hr		9
embryo 14-16hr		5
embryo 16-18hr		6
embryo 18-20hr		6
embryo 20-22hr		5
embryo 22-24hr		6
larva L1		5
larva L2		6
larva L3 12hr old		4
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		17
white prepupae new		15
white prepupae 12hr		15
white prepupae 24hr		13
pupae 2d postWPP		12
pupae 3d postWPP		8
pupae 4d postWPP		5
adult male 01day		10
adult male 05day		11
adult male 30day		11
adult female 01day		8
adult female 05day		15
adult female 30day		15
Expression Level Scale		Very low Low Moderate

log, scaled to Moderate expression
Developmental Stage		Expression Level
embryo 00-02hr		14
embryo 02-04hr		3
embryo 04-06hr		6
embryo 06-08hr		9
embryo 08-10hr		9
embryo 10-12hr		8
embryo 12-14hr		9
embryo 14-16hr		5
embryo 16-18hr		6
embryo 18-20hr		6
embryo 20-22hr		5
embryo 22-24hr		6
larva L1		5
larva L2		6
larva L3 12hr old		4
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		17
white prepupae new		15
white prepupae 12hr		15
white prepupae 24hr		13
pupae 2d postWPP		12
pupae 3d postWPP		8
pupae 4d postWPP		5
adult male 01day		10
adult male 05day		11
adult male 30day		11
adult female 01day		8
adult female 05day		15
adult female 30day		15
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Developmental Stage		Expression Level
embryo 00-02hr		14
embryo 02-04hr		3
embryo 04-06hr		6
embryo 06-08hr		9
embryo 08-10hr		9
embryo 10-12hr		8
embryo 12-14hr		9
embryo 14-16hr		5
embryo 16-18hr		6
embryo 18-20hr		6
embryo 20-22hr		5
embryo 22-24hr		6
larva L1		5
larva L2		6
larva L3 12hr old		4
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		17
white prepupae new		15
white prepupae 12hr		15
white prepupae 24hr		13
pupae 2d postWPP		12
pupae 3d postWPP		8
pupae 4d postWPP		5
adult male 01day		10
adult male 05day		11
adult male 30day		11
adult female 01day		8
adult female 05day		15
adult female 30day		15
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Developmental Stage		Expression Level
embryo 00-02hr		14
embryo 02-04hr		3
embryo 04-06hr		6
embryo 06-08hr		9
embryo 08-10hr		9
embryo 10-12hr		8
embryo 12-14hr		9
embryo 14-16hr		5
embryo 16-18hr		6
embryo 18-20hr		6
embryo 20-22hr		5
embryo 22-24hr		6
larva L1		5
larva L2		6
larva L3 12hr old		4
larva L3 puffstage 1-2		8
larva L3 puffstage 3-6		11
larva L3 puffstage 7-9		17
white prepupae new		15
white prepupae 12hr		15
white prepupae 24hr		13
pupae 2d postWPP		12
pupae 3d postWPP		8
pupae 4d postWPP		5
adult male 01day		10
adult male 05day		11
adult male 30day		11
adult female 01day		8
adult female 05day		15
adult female 30day		15
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Developmental Stage		Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day

modENCODE Temporal Expression Data (Graveley et al., 2011)

modENCODE Cell Lines RNA-Seq

modENCODE Cell Line Expression Data

(modENCODE_mRNA-Seq_cell.A)

(modENCODE_mRNA-Seq_cell.B)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		24
Schneider line 2 Sg4		6
embryonic 1182-4H		15
embryonic GM2		29
embryonic Kc167		30
embryonic S1		25
embryonic S3		12
leg disc CME L1		14
wing disc CME-W2		15
wing disc ML-DmD8		11
wing disc ML-DmD9		17
wing disc ML-DmD16-c3		15
wing disc ML-DmD21		8
wing disc ML-DmD32		10
haltere disc ML-DmD17-c3		13
eye-antennal disc ML-DmD11		19
antennal disc ML-DmD20-c5		14
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		18
tumorous blood cells mbn2		12
ovary fGS/OSS		24
ovary OSC		19
ovary OSS		9
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		24
Schneider line 2 Sg4		6
embryonic 1182-4H		15
embryonic GM2		(29)
embryonic Kc167		(30)
embryonic S1		25
embryonic S3		12
leg disc CME L1		14
wing disc CME-W2		15
wing disc ML-DmD8		11
wing disc ML-DmD9		17
wing disc ML-DmD16-c3		15
wing disc ML-DmD21		8
wing disc ML-DmD32		10
haltere disc ML-DmD17-c3		13
eye-antennal disc ML-DmD11		19
antennal disc ML-DmD20-c5		14
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		18
tumorous blood cells mbn2		12
ovary fGS/OSS		24
ovary OSC		19
ovary OSS		9
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		24
Schneider line 2 Sg4		6
embryonic 1182-4H		15
embryonic GM2		29
embryonic Kc167		30
embryonic S1		25
embryonic S3		12
leg disc CME L1		14
wing disc CME-W2		15
wing disc ML-DmD8		11
wing disc ML-DmD9		17
wing disc ML-DmD16-c3		15
wing disc ML-DmD21		8
wing disc ML-DmD32		10
haltere disc ML-DmD17-c3		13
eye-antennal disc ML-DmD11		19
antennal disc ML-DmD20-c5		14
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		18
tumorous blood cells mbn2		12
ovary fGS/OSS		24
ovary OSC		19
ovary OSS		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		24
Schneider line 2 Sg4		6
embryonic 1182-4H		15
embryonic GM2		29
embryonic Kc167		30
embryonic S1		25
embryonic S3		12
leg disc CME L1		14
wing disc CME-W2		15
wing disc ML-DmD8		11
wing disc ML-DmD9		17
wing disc ML-DmD16-c3		15
wing disc ML-DmD21		8
wing disc ML-DmD32		10
haltere disc ML-DmD17-c3		13
eye-antennal disc ML-DmD11		19
antennal disc ML-DmD20-c5		14
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		18
tumorous blood cells mbn2		12
ovary fGS/OSS		24
ovary OSC		19
ovary OSS		9
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Cell Line		Expression Level
Schneider line 2 S2R+		24
Schneider line 2 Sg4		6
embryonic 1182-4H		15
embryonic GM2		29
embryonic Kc167		30
embryonic S1		25
embryonic S3		12
leg disc CME L1		14
wing disc CME-W2		15
wing disc ML-DmD8		11
wing disc ML-DmD9		17
wing disc ML-DmD16-c3		15
wing disc ML-DmD21		8
wing disc ML-DmD32		10
haltere disc ML-DmD17-c3		13
eye-antennal disc ML-DmD11		19
antennal disc ML-DmD20-c5		14
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		18
tumorous blood cells mbn2		12
ovary fGS/OSS		24
ovary OSC		19
ovary OSS		9
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Cell Line		Expression Level
Schneider line 2 S2R+		24
Schneider line 2 Sg4		6
embryonic 1182-4H		15
embryonic GM2		29
embryonic Kc167		30
embryonic S1		25
embryonic S3		12
leg disc CME L1		14
wing disc CME-W2		15
wing disc ML-DmD8		11
wing disc ML-DmD9		17
wing disc ML-DmD16-c3		15
wing disc ML-DmD21		8
wing disc ML-DmD32		10
haltere disc ML-DmD17-c3		13
eye-antennal disc ML-DmD11		19
antennal disc ML-DmD20-c5		14
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		18
tumorous blood cells mbn2		12
ovary fGS/OSS		24
ovary OSC		19
ovary OSS		9
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Cell Line		Expression Level
Schneider line 2 S2R+		24
Schneider line 2 Sg4		6
embryonic 1182-4H		15
embryonic GM2		29
embryonic Kc167		30
embryonic S1		25
embryonic S3		12
leg disc CME L1		14
wing disc CME-W2		15
wing disc ML-DmD8		11
wing disc ML-DmD9		17
wing disc ML-DmD16-c3		15
wing disc ML-DmD21		8
wing disc ML-DmD32		10
haltere disc ML-DmD17-c3		13
eye-antennal disc ML-DmD11		19
antennal disc ML-DmD20-c5		14
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		18
tumorous blood cells mbn2		12
ovary fGS/OSS		24
ovary OSC		19
ovary OSS		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Cell Line		Expression Level
Schneider line 2 S2R+		24
Schneider line 2 Sg4		6
embryonic 1182-4H		15
embryonic GM2		29
embryonic Kc167		30
embryonic S1		25
embryonic S3		12
leg disc CME L1		14
wing disc CME-W2		15
wing disc ML-DmD8		11
wing disc ML-DmD9		17
wing disc ML-DmD16-c3		15
wing disc ML-DmD21		8
wing disc ML-DmD32		10
haltere disc ML-DmD17-c3		13
eye-antennal disc ML-DmD11		19
antennal disc ML-DmD20-c5		14
mixed discs ML-DmD4-c1		10
CNS ML-DmBG1-c1		14
CNS ML-DmBG2-c2		18
tumorous blood cells mbn2		12
ovary fGS/OSS		24
ovary OSC		19
ovary OSS		9
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Cell Line		Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS

modENCODE Treatments RNA-Seq

modENCODE Treatment Expression Data

(modENCODE_mRNA-Seq_treatments)

	Styles
	Linear
	Logarithmic
	Heatmap
	Scales
	gene max expression
	Moderate expression bin max
	High expression bin max
	Extremely high expression bin max

[download data (TSV)]

Guide to modENCODE expression level colors
	No/Extremely low expression (0 - 0)
	Very low expression (1 - 3)
	Low expression (4 - 10)
	Moderate expression (11 - 25)
	Moderately high expression (26 - 50)
	High expression (51 - 100)
	Very high expression (101 - 1000)
	Extremely high expression (>1000)

Linear, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		6
heat shock, 4-day adult		12
Cadmium 50 mM 6 hrs, larvae L3		10
Cadmium 50 mM 12 hrs, larvae L3		19
Cadmium 50 mM 48 hrs, 4-day adult		15
Cadmium 100 mM 48 hrs, 4-day adult		25
Copper 0.5 mM 12 hrs, larvae L3		6
Copper 15 mM 48 hrs, 4-day adult		16
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		16
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		12
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		25
Caffeine 25 mg/ml 48 hrs, 4-day adult		7
Paraquat 5 mM 48 hrs, 4-day adult		23
Paraquat 10 mM 48 hrs, 4-day adult		20
Rotenone 2 μg 12 hrs, larvae L3		16
Rotenone 8 μg 12 hrs, larvae L3		8
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		6
heat shock, 4-day adult		12
Cadmium 50 mM 6 hrs, larvae L3		10
Cadmium 50 mM 12 hrs, larvae L3		19
Cadmium 50 mM 48 hrs, 4-day adult		15
Cadmium 100 mM 48 hrs, 4-day adult		25
Copper 0.5 mM 12 hrs, larvae L3		6
Copper 15 mM 48 hrs, 4-day adult		16
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		16
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		12
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		25
Caffeine 25 mg/ml 48 hrs, 4-day adult		7
Paraquat 5 mM 48 hrs, 4-day adult		23
Paraquat 10 mM 48 hrs, 4-day adult		20
Rotenone 2 μg 12 hrs, larvae L3		16
Rotenone 8 μg 12 hrs, larvae L3		8
Expression Level Scale		Very low Low Moderate Moderately high

Linear, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		6
heat shock, 4-day adult		12
Cadmium 50 mM 6 hrs, larvae L3		10
Cadmium 50 mM 12 hrs, larvae L3		19
Cadmium 50 mM 48 hrs, 4-day adult		15
Cadmium 100 mM 48 hrs, 4-day adult		25
Copper 0.5 mM 12 hrs, larvae L3		6
Copper 15 mM 48 hrs, 4-day adult		16
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		16
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		12
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		25
Caffeine 25 mg/ml 48 hrs, 4-day adult		7
Paraquat 5 mM 48 hrs, 4-day adult		23
Paraquat 10 mM 48 hrs, 4-day adult		20
Rotenone 2 μg 12 hrs, larvae L3		16
Rotenone 8 μg 12 hrs, larvae L3		8
Expression Level Scale		Very low Low Moderate Moderately high High Very high

Linear, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		6
heat shock, 4-day adult		12
Cadmium 50 mM 6 hrs, larvae L3		10
Cadmium 50 mM 12 hrs, larvae L3		19
Cadmium 50 mM 48 hrs, 4-day adult		15
Cadmium 100 mM 48 hrs, 4-day adult		25
Copper 0.5 mM 12 hrs, larvae L3		6
Copper 15 mM 48 hrs, 4-day adult		16
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		16
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		12
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		25
Caffeine 25 mg/ml 48 hrs, 4-day adult		7
Paraquat 5 mM 48 hrs, 4-day adult		23
Paraquat 10 mM 48 hrs, 4-day adult		20
Rotenone 2 μg 12 hrs, larvae L3		16
Rotenone 8 μg 12 hrs, larvae L3		8
Expression Level Scale		Extremely high

log, scaled to maximum expression level
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		6
heat shock, 4-day adult		12
Cadmium 50 mM 6 hrs, larvae L3		10
Cadmium 50 mM 12 hrs, larvae L3		19
Cadmium 50 mM 48 hrs, 4-day adult		15
Cadmium 100 mM 48 hrs, 4-day adult		25
Copper 0.5 mM 12 hrs, larvae L3		6
Copper 15 mM 48 hrs, 4-day adult		16
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		16
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		12
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		25
Caffeine 25 mg/ml 48 hrs, 4-day adult		7
Paraquat 5 mM 48 hrs, 4-day adult		23
Paraquat 10 mM 48 hrs, 4-day adult		20
Rotenone 2 μg 12 hrs, larvae L3		16
Rotenone 8 μg 12 hrs, larvae L3		8
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to Moderate expression
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		6
heat shock, 4-day adult		12
Cadmium 50 mM 6 hrs, larvae L3		10
Cadmium 50 mM 12 hrs, larvae L3		19
Cadmium 50 mM 48 hrs, 4-day adult		15
Cadmium 100 mM 48 hrs, 4-day adult		25
Copper 0.5 mM 12 hrs, larvae L3		6
Copper 15 mM 48 hrs, 4-day adult		16
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		16
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		12
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		25
Caffeine 25 mg/ml 48 hrs, 4-day adult		7
Paraquat 5 mM 48 hrs, 4-day adult		23
Paraquat 10 mM 48 hrs, 4-day adult		20
Rotenone 2 μg 12 hrs, larvae L3		16
Rotenone 8 μg 12 hrs, larvae L3		8
Expression Level Scale		Very low Low Moderate Moderately high

log, scaled to High expression
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		6
heat shock, 4-day adult		12
Cadmium 50 mM 6 hrs, larvae L3		10
Cadmium 50 mM 12 hrs, larvae L3		19
Cadmium 50 mM 48 hrs, 4-day adult		15
Cadmium 100 mM 48 hrs, 4-day adult		25
Copper 0.5 mM 12 hrs, larvae L3		6
Copper 15 mM 48 hrs, 4-day adult		16
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		16
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		12
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		25
Caffeine 25 mg/ml 48 hrs, 4-day adult		7
Paraquat 5 mM 48 hrs, 4-day adult		23
Paraquat 10 mM 48 hrs, 4-day adult		20
Rotenone 2 μg 12 hrs, larvae L3		16
Rotenone 8 μg 12 hrs, larvae L3		8
Expression Level Scale		Very low Low Moderate Moderately high High Very high

log, scaled to Extremely high expression
Treatment		Expression Level
extended cold, 4-day adult		9
cold shock, 4-day adult		6
heat shock, 4-day adult		12
Cadmium 50 mM 6 hrs, larvae L3		10
Cadmium 50 mM 12 hrs, larvae L3		19
Cadmium 50 mM 48 hrs, 4-day adult		15
Cadmium 100 mM 48 hrs, 4-day adult		25
Copper 0.5 mM 12 hrs, larvae L3		6
Copper 15 mM 48 hrs, 4-day adult		16
Zinc 5 mM 12 hrs, larvae L3		9
Zinc 4.5 mM 48 hrs, 4-day adult		16
Ethanol 2.5% 3 hrs, larvae L3		22
Ethanol 5% 3 hrs, larvae L3		12
Ethanol 10% 3 hrs, larvae L3		8
Caffeine 1.5 mg/ml 4 hrs, larvae L3		16
Caffeine 2.5 mg/ml 48 hrs, 4-day adult		25
Caffeine 25 mg/ml 48 hrs, 4-day adult		7
Paraquat 5 mM 48 hrs, 4-day adult		23
Paraquat 10 mM 48 hrs, 4-day adult		20
Rotenone 2 μg 12 hrs, larvae L3		16
Rotenone 8 μg 12 hrs, larvae L3		8
Expression Level Scale		Very low Low Moderate Moderately high High Very high Extremely high

Heatmap
Treatment		Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3

Expression Clusters

A cluster of genes with similar mRNA expression dynamics across development.

(The modENCODE Consortium, 2010, Graveley et al., 2011)

External Data & Images

Linkouts

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0030694

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG15602-RA

Alleles & Phenotypes

Summary of Allele Phenotypes

Lethality

Allele

viable, with Scer\GAL4^pnr-MD237

CG15602^GD9067

Phenotype manifest in

Allele

Classical Alleles ( 0 )

For All Classical Alleles Show

Allele of CG15602	Class	Mutagen	Stocks	Known lesion

Alleles Carried on Transgenic Constructs ( 3 )

For All Alleles Carried on Transgenic Constructs Show

Allele of CG15602	Mutagen	Stocks	Known lesion
CG15602^GD9067	in vitro construct - RNAi in vitro construct - regulatory fusion	2	Yes
CG15602^KK100425	in vitro construct - RNAi in vitro construct - regulatory fusion	1	Yes
CG15602^NIG.15602R	in vitro construct - RNAi in vitro construct - regulatory fusion	0	Yes

Aneuploid Aberrations

Disrupted in

Df(1)Exel6250

(Ryder, 2004.4.26)

Transgenic Constructs & Insertions

Transgenic Constructs

Type of construct

Name

Expression data

UAS construct

P{GD9067}

P{KK100425}

P{NIG.15602R}

Insertions

Type of insertions

Name

Expression data

Gene Ontology: Function, Process & Cellular Component ( 0 unique terms )

Terms Based on Experimental Evidence ( 0 terms )

Terms Based on Predictions or Assertions ( 0 terms )

Sequence Ontology: Class of Gene

nuclear_gene

protein_coding_gene

Interactions & Pathways

Summary of Physical Interactions

protein-protein

Interacting group

Assay

References

CG15602 - mib2

anti tag coimmunoprecipitation, peptide massfingerprinting

(Mintseris et al., 2009.11.23)

Summary of Genetic Interactions

Interacts with

Please look at the allele data for full details of the genetic interactions

CG15602 allele

Gene

References

External Data

Linkouts

BioGRID - A database of protein and genetic interactions

•

58881

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0030694

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

32533

Orthologs

OrthoDB Orthologs (33) - based on analysis using Dmel annotation version 5.41

OrthoDB Ortholog Groups

OrthoDB orthology group searches

(Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288)

Drosophila inclusive ortholog search

EOG6S1TTB

Dipteran inclusive ortholog search

EOG61VKBT

Insect inclusive ortholog search

EOG6TQK6G

Arthropod inclusive ortholog search

EOG6Z8WCW

Metazoa inclusive ortholog search

EOG6DJXRD

Orthologs in Drosophila Species (EOG6S1TTB)

Organism

Common Name

Gene

AAA Syntenic Ortholog

Multiple Dmel Genes in this Orthologous Group

Drosophila melanogaster

fruit fly

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila persimilis

Dper\GL18057

Drosophila willistoni

Dwil\GK25124

Drosophila virilis

Dvir\GJ18478

Drosophila mojavensis

Dmoj\GI11195

Drosophila grimshawi

Dgri\GH12533

Orthologs in non-Drosophila Dipterans (EOG61VKBT)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Aedes aegypti

Yellow fever mosquito

Aaeg\AAEL010052

Anopheles gambiae

Malaria mosquito

Agam\AGAP002064

Culex quinquefasciatus

Southern house mosquito

Cqui\CPIJ003352

Orthologs in non-Dipteran Insects (EOG6TQK6G)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Apis mellifera

Western honey bee

Amel\GB54087

Nasonia vitripennis

Parasitic wasp

Nvit\Nasvi2EG008868

Acromyrmex echinatior

Panamanian leafcutter ant

Aech\AECH26638

Atta cephalotes

Leafcutter ant

Acep\ACEP25987

Camponotus floridanus

Florida carpenter ant

Cflo\CFLO13936

Harpegnathos saltator

Jerdons jumping ant

Hsal\HSAL22603

Linepithema humile

Argentine ant

Lhum\LH18782

Pogonomyrmex barbatus

Red harvester ant

Pbar\PB12570

Solenopsis invicta

Red fire ant

Sinv\SINV17389

Pediculus humanus

Human body louse

Phum\PHUM399910

Tribolium castaneum

Red flour beetle

Tcas\TC009615

Orthologs in non-Insect Arthropods (EOG6Z8WCW)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Daphnia pulex

Water flea

Dpux\ndhF

Orthologs in non-Arthropod Metazoa (EOG6DJXRD)

Organism

Common Name

Gene

Multiple Dmel Genes in this Orthologous Group

Caenorhabditis elegans

Nematode

Cele\R11D1.10

Strongylocentrotus purpuratus

Purple sea urchin

Spur\SPU_006626gn

Danio rerio

Zebrafish

Drer\zgc:92683

Xenopus tropicalis

Western clawed frog

Xtro\zfyve19

Gallus gallus

Domestic chicken

Ggal\ZFYVE19

Mus musculus

House mouse

Mmus\Zfyve19

Rattus norvegicus

Norway rat

Rnor\Zfyve19

Homo sapiens

Human

Hsap\ENSG00000166140

Human Orthologs (1)

Gene

OMIM

HGNC

Hsap\ENSG00000166140

AAA Orthologs (9) based on analysis using Dmel annotation version 4.3

Organism

Gene

Drosophila simulans

Drosophila sechellia

Drosophila erecta

Drosophila yakuba

Drosophila persimilis

Dper\GL18057

Drosophila willistoni

Dwil\GK25124

Drosophila virilis

Dvir\GJ18478

Drosophila mojavensis

Dmoj\GI11195

Drosophila grimshawi

Dgri\GH12533

Stocks & Reagents

Stocks Listed in FlyBase ( 3 )

VDRC

v103395

P{KK100425}VIE-260B

v40000

w¹¹¹⁸; P{GD9067}v40000

v40001

w¹¹¹⁸; P{GD9067}v40001

Genomic Clones ( 2 )

Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete

cDNA Clones ( 30 )

Please Note

This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.

cDNA Clones, Fully Sequenced

BDGP DGC clones

Other clones

cDNA Clones, End Sequenced (ESTs)

BDGP DGC clones

Other clones

RNAi & Array Information

Linkouts

DRSC - Results from RNAi screens.

•

FBgn0030694

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

32533

Antibody Information

Other Information

Discoverer

Etymology

Identification

Relationship to Other Genes

Source for database identity of

Source for database merge of

Additional comments

Other Comments

External Crossreferences & Linkouts

Sequence Crossreferences

RefSeq (Transcripts)

•

NM_132849

RefSeq (Proteins)

•

NP_573077

DDBJ / EMBL / GenBank

•

AAF48518

Entrez Gene - A searchable database of RefSeq genes.

•

32533

UniProtKB/TrEMBL

•

Q4QQ70

Other Crossreferences

InterPro domains - A database of protein families, domains, and functional sites

•

Zinc finger, RING/FYVE/PHD-type (IPR013083)

Zinc finger, FYVE-related (IPR017455)

Zinc finger, FYVE/PHD-type (IPR011011)

Linkouts

BioGRID - A database of protein and genetic interactions

•

58881

DroID - A comprehensive database of gene and protein interactions.

•

FBgn0030694

DRSC - Results from RNAi screens.

•

FBgn0030694

FLIGHT - Cell culture data for RNAi and other high-throughput technologies

•

FBgn0030694

FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array

•

CG15602-RA

FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans

•

FBgn0030694

GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents

•

32533

InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets.

•

32533

modMine - Data generated by the modENCODE project.

•

FBgn0030694

Synonyms & Secondary IDs ( 1 )

Reported As

Symbol Synonym

CG15602

(Keleman et al., 2009.8.5, Japanese National Institute of Genetics, 2012.5.21)

Name Synonym

Secondary FlyBase IDs

References ( 10 )

Supplementary material

Graveley et al., 2011, Nature 471(7339):: Supplementary Table 33. Fuzzy Cluster Members. [FBrf0213980]
The modENCODE Consortium, 2010, Science 330(6012):: DataS14: Gene co-expression clusters. [FBrf0213979]
Mummery-Widmer et al., 2009, Nature 458(7241):: Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518]
Giot et al., 2003, Science 302(5651):: Tables S1 to S7. [FBrf0166452]

Personal communication to FlyBase

Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510]
Mintseris et al., 2009.11.23, DPiM: the Drosophila Protein Interaction Mapping project: DPiM: the Drosophila Protein Interaction Mapping project [FBrf0209452]
Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center: RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327]
Ryder, 2004.4.26, Exelixis CG deletion data.: Exelixis CG deletion data. [FBrf0184335]

Stock list

Japanese National Institute of Genetics, 2012.5.21, RNAi stocks available from NIG-FLY.: RNAi stocks available from NIG-FLY. [FBrf0218457]