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Gene Dmel\CG8924

General Information
Symbol	Dmel\CG8924	Species	D. melanogaster
Name		Annotation symbol	CG8924
Feature type	protein_coding_gene	FlyBase ID	FBgn0030710
Gene Model Status	Current	Stock availability	7 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	14A1-14A1	Sequence location	X:15,835,112..15,838,482 [+]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG8924 (FBgn0030710). It is a protein_coding_gene from Drosophila melanogaster. It is reported to have molecular function: DNA binding. The biological processes in which it is involved are not known. 6 alleles are reported. No phenotypic data is available. It has one annotated transcript and one annotated polypeptide. Protein features are: BTB/POZ; BTB/POZ fold; BTB/POZ-like; Helix-turn-helix, Psq-like. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult ovary. Comments on Affy2 ProbeSet: ProbeSet 1636096_at completely aligns to an exonic region of the only FlyBase-annotated transcript isoform of CG8924. Gene sequence location is X:15835112..15838482.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
Update Feed	Click the icon below to subscribe to this FlyBase record and receive updates automatically through your feed reader.
FB2012_01	Sequence features BKN26771 BKN46278 HFA20122
FB2011_10
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 14A1-14A1   Limits computationally determined from genome sequence between P{EP}Gβ13FEP1071 and P{EP}EP1458&P{EP}EP1522
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG8924 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG8924-RB FBtr0074130  NM_132863   2573   514
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG8924-PB   FBpp0073935   55.8   514   6.91     NP_573091   AAF48544
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • BTB/POZ-like (IPR000210) Helix-turn-helix, Psq-like (IPR011526) BTB/POZ (IPR013069) BTB/POZ fold (IPR011333)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA246250   AA264695   AA439364   AA539852   AA568036   AA802579   AA949798   AE014298 AAF48544   AI515123   AI516133   AW942517   AY061260 AAL28808   BI170013   BI232263   BI240883   BI243612   BI363403   BI364687   BI370753   BI483716   BP545451   BP545452   BZ286376   BZ286377   CO155642   CO263562   CO277501   CO282728   CO283492   CO297887   CO299855   CO302187   CO308923   CO322298   CO326392   CO330925   CO339428   CO343106   CZ479479   CZ489135   CZ489136   EC060291   EC063320   EC070516   EC083822   EC085743   EC206308   EC206532   EC211086   EC211252   EC212126   EC215114   EC216003   EC223531   EC230970   EC234075   EC238148   EC250839   EC253083   EC257318   EC258928   EC266594
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q9VXL5
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0030710    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0030710 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed within 00-06 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0030710 expression level Developmental Stage   Expression Level embryo 00-02hr    5514 embryo 02-04hr    5285 embryo 04-06hr    2383 embryo 06-08hr    2779 embryo 08-10hr    2649 embryo 10-12hr    1666 embryo 12-14hr    1648 embryo 14-16hr    1536 embryo 16-18hr    1272 embryo 18-20hr    717 embryo 20-22hr    1281 embryo 22-24hr    1468 larva L1    296 larva L2    135 larva L3 12hr old    104 larva L3 puffstage 1-2    198 larva L3 puffstage 3-6    444 larva L3 puffstage 7-9    611 white prepupae new    650 white prepupae 12hr    780 white prepupae 24hr    1151 pupae 2d postWPP    534 pupae 3d postWPP    270 pupae 4d postWPP    211 adult male 01day    200 adult male 05day    213 adult male 30day    247 adult female 01day    1197 adult female 05day    2592 adult female 30day    2597 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (5514) embryo 02-04hr  (5285) embryo 04-06hr  (2383) embryo 06-08hr  (2779) embryo 08-10hr  (2649) embryo 10-12hr  (1666) embryo 12-14hr  (1648) embryo 14-16hr  (1536) embryo 16-18hr  (1272) embryo 18-20hr  (717) embryo 20-22hr  (1281) embryo 22-24hr  (1468) larva L1  (296) larva L2  (135) larva L3 12hr old  104 larva L3 puffstage 1-2  (198) larva L3 puffstage 3-6  (444) larva L3 puffstage 7-9  (611) white prepupae new  (650) white prepupae 12hr  (780) white prepupae 24hr  (1151) pupae 2d postWPP  (534) pupae 3d postWPP  (270) pupae 4d postWPP  (211) adult male 01day  (200) adult male 05day  (213) adult male 30day  (247) adult female 01day  (1197) adult female 05day  (2592) adult female 30day  (2597) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (5514) embryo 02-04hr  (5285) embryo 04-06hr  (2383) embryo 06-08hr  (2779) embryo 08-10hr  (2649) embryo 10-12hr  (1666) embryo 12-14hr  (1648) embryo 14-16hr  (1536) embryo 16-18hr    1272 embryo 18-20hr    717 embryo 20-22hr    1281 embryo 22-24hr  1468 larva L1    296 larva L2    135 larva L3 12hr old    104 larva L3 puffstage 1-2    198 larva L3 puffstage 3-6    444 larva L3 puffstage 7-9    611 white prepupae new    650 white prepupae 12hr    780 white prepupae 24hr    1151 pupae 2d postWPP    534 pupae 3d postWPP    270 pupae 4d postWPP    211 adult male 01day    200 adult male 05day    213 adult male 30day    247 adult female 01day    1197 adult female 05day  (2592) adult female 30day  (2597) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5514 embryo 02-04hr    5285 embryo 04-06hr    2383 embryo 06-08hr    2779 embryo 08-10hr    2649 embryo 10-12hr    1666 embryo 12-14hr    1648 embryo 14-16hr    1536 embryo 16-18hr    1272 embryo 18-20hr    717 embryo 20-22hr    1281 embryo 22-24hr    1468 larva L1    296 larva L2    135 larva L3 12hr old    104 larva L3 puffstage 1-2    198 larva L3 puffstage 3-6    444 larva L3 puffstage 7-9    611 white prepupae new    650 white prepupae 12hr    780 white prepupae 24hr    1151 pupae 2d postWPP    534 pupae 3d postWPP    270 pupae 4d postWPP    211 adult male 01day    200 adult male 05day    213 adult male 30day    247 adult female 01day    1197 adult female 05day    2592 adult female 30day    2597 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5514 embryo 02-04hr    5285 embryo 04-06hr    2383 embryo 06-08hr    2779 embryo 08-10hr    2649 embryo 10-12hr    1666 embryo 12-14hr    1648 embryo 14-16hr    1536 embryo 16-18hr    1272 embryo 18-20hr    717 embryo 20-22hr    1281 embryo 22-24hr    1468 larva L1    296 larva L2    135 larva L3 12hr old    104 larva L3 puffstage 1-2    198 larva L3 puffstage 3-6    444 larva L3 puffstage 7-9    611 white prepupae new    650 white prepupae 12hr    780 white prepupae 24hr    1151 pupae 2d postWPP    534 pupae 3d postWPP    270 pupae 4d postWPP    211 adult male 01day    200 adult male 05day    213 adult male 30day    247 adult female 01day    1197 adult female 05day    2592 adult female 30day    2597 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0030710 expression level Developmental Stage   Expression Level embryo 00-02hr    5514 embryo 02-04hr    5285 embryo 04-06hr    2383 embryo 06-08hr    2779 embryo 08-10hr    2649 embryo 10-12hr    1666 embryo 12-14hr    1648 embryo 14-16hr    1536 embryo 16-18hr    1272 embryo 18-20hr    717 embryo 20-22hr    1281 embryo 22-24hr    1468 larva L1    296 larva L2    135 larva L3 12hr old    104 larva L3 puffstage 1-2    198 larva L3 puffstage 3-6    444 larva L3 puffstage 7-9    611 white prepupae new    650 white prepupae 12hr    780 white prepupae 24hr    1151 pupae 2d postWPP    534 pupae 3d postWPP    270 pupae 4d postWPP    211 adult male 01day    200 adult male 05day    213 adult male 30day    247 adult female 01day    1197 adult female 05day    2592 adult female 30day    2597 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (5514) embryo 02-04hr  (5285) embryo 04-06hr  (2383) embryo 06-08hr  (2779) embryo 08-10hr  (2649) embryo 10-12hr  (1666) embryo 12-14hr  (1648) embryo 14-16hr  (1536) embryo 16-18hr  (1272) embryo 18-20hr  (717) embryo 20-22hr  (1281) embryo 22-24hr  (1468) larva L1  (296) larva L2  135 larva L3 12hr old  104 larva L3 puffstage 1-2  (198) larva L3 puffstage 3-6  (444) larva L3 puffstage 7-9  (611) white prepupae new  (650) white prepupae 12hr  (780) white prepupae 24hr  (1151) pupae 2d postWPP  (534) pupae 3d postWPP  (270) pupae 4d postWPP  (211) adult male 01day  (200) adult male 05day  (213) adult male 30day  (247) adult female 01day  (1197) adult female 05day  (2592) adult female 30day  (2597) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (5514) embryo 02-04hr  (5285) embryo 04-06hr  2383 embryo 06-08hr  (2779) embryo 08-10hr  (2649) embryo 10-12hr  1666 embryo 12-14hr  1648 embryo 14-16hr  1536 embryo 16-18hr    1272 embryo 18-20hr    717 embryo 20-22hr    1281 embryo 22-24hr  1468 larva L1    296 larva L2    135 larva L3 12hr old    104 larva L3 puffstage 1-2    198 larva L3 puffstage 3-6    444 larva L3 puffstage 7-9    611 white prepupae new    650 white prepupae 12hr    780 white prepupae 24hr    1151 pupae 2d postWPP    534 pupae 3d postWPP    270 pupae 4d postWPP    211 adult male 01day    200 adult male 05day    213 adult male 30day    247 adult female 01day    1197 adult female 05day  (2592) adult female 30day  (2597) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    5514 embryo 02-04hr    5285 embryo 04-06hr    2383 embryo 06-08hr    2779 embryo 08-10hr    2649 embryo 10-12hr    1666 embryo 12-14hr    1648 embryo 14-16hr    1536 embryo 16-18hr    1272 embryo 18-20hr    717 embryo 20-22hr    1281 embryo 22-24hr    1468 larva L1    296 larva L2    135 larva L3 12hr old    104 larva L3 puffstage 1-2    198 larva L3 puffstage 3-6    444 larva L3 puffstage 7-9    611 white prepupae new    650 white prepupae 12hr    780 white prepupae 24hr    1151 pupae 2d postWPP    534 pupae 3d postWPP    270 pupae 4d postWPP    211 adult male 01day    200 adult male 05day    213 adult male 30day    247 adult female 01day    1197 adult female 05day    2592 adult female 30day    2597 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    5514 embryo 02-04hr    5285 embryo 04-06hr    2383 embryo 06-08hr    2779 embryo 08-10hr    2649 embryo 10-12hr    1666 embryo 12-14hr    1648 embryo 14-16hr    1536 embryo 16-18hr    1272 embryo 18-20hr    717 embryo 20-22hr    1281 embryo 22-24hr    1468 larva L1    296 larva L2    135 larva L3 12hr old    104 larva L3 puffstage 1-2    198 larva L3 puffstage 3-6    444 larva L3 puffstage 7-9    611 white prepupae new    650 white prepupae 12hr    780 white prepupae 24hr    1151 pupae 2d postWPP    534 pupae 3d postWPP    270 pupae 4d postWPP    211 adult male 01day    200 adult male 05day    213 adult male 30day    247 adult female 01day    1197 adult female 05day    2592 adult female 30day    2597 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0030710    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0030710 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult central nervous system, adult ovary. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0030710 expression level Tissue   Expression Level Larval Central Nervous System    216.975 Larval Midgut    6.7 Larval Hindgut    18.1 Larval Malpighian Tubules    5.1 Larval Fat Body    8.1 Larval Salivary Gland    7.6 Larval Trachea    26.65 Larval Carcass no informative data Adult Head    52.4 Adult Eye    30.75 Adult Brain    220.3 Adult Thoracic-Abdominal Ganglion    174.3 Adult Crop    23.8 Adult Midgut    6.6 Adult Hindgut no informative data Adult Malpighian Tubules    5.6 Adult Fat Body    2.6 Adult Salivary Gland    5.1 Adult Heart    5.4 Adult VirginFemale Spermatheca    5.7 Adult InseminatedFemale Spermatheca    3.9 Adult Ovary    396.1 Adult Testis    17.3 Adult Male Accessory Gland    5.7 Adult Carcass    6.7 Expression Level Scale  None   Low   Moderate  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    216.975 Larval Midgut    6.7 Larval Hindgut    18.1 Larval Malpighian Tubules    5.1 Larval Fat Body    8.1 Larval Salivary Gland    7.6 Larval Trachea    26.65 Larval Carcass no informative data Adult Head    52.4 Adult Eye    30.75 Adult Brain    220.3 Adult Thoracic-Abdominal Ganglion    174.3 Adult Crop    23.8 Adult Midgut    6.6 Adult Hindgut no informative data Adult Malpighian Tubules    5.6 Adult Fat Body    2.6 Adult Salivary Gland    5.1 Adult Heart    5.4 Adult VirginFemale Spermatheca    5.7 Adult InseminatedFemale Spermatheca    3.9 Adult Ovary    396.1 Adult Testis    17.3 Adult Male Accessory Gland    5.7 Adult Carcass    6.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    216.975 Larval Midgut    6.7 Larval Hindgut    18.1 Larval Malpighian Tubules    5.1 Larval Fat Body    8.1 Larval Salivary Gland    7.6 Larval Trachea    26.65 Larval Carcass no informative data Adult Head    52.4 Adult Eye    30.75 Adult Brain    220.3 Adult Thoracic-Abdominal Ganglion    174.3 Adult Crop    23.8 Adult Midgut    6.6 Adult Hindgut no informative data Adult Malpighian Tubules    5.6 Adult Fat Body    2.6 Adult Salivary Gland    5.1 Adult Heart    5.4 Adult VirginFemale Spermatheca    5.7 Adult InseminatedFemale Spermatheca    3.9 Adult Ovary    396.1 Adult Testis    17.3 Adult Male Accessory Gland    5.7 Adult Carcass    6.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    216.975 Larval Midgut    6.7 Larval Hindgut    18.1 Larval Malpighian Tubules    5.1 Larval Fat Body    8.1 Larval Salivary Gland    7.6 Larval Trachea    26.65 Larval Carcass no informative data Adult Head    52.4 Adult Eye    30.75 Adult Brain    220.3 Adult Thoracic-Abdominal Ganglion    174.3 Adult Crop    23.8 Adult Midgut    6.6 Adult Hindgut no informative data Adult Malpighian Tubules    5.6 Adult Fat Body    2.6 Adult Salivary Gland    5.1 Adult Heart    5.4 Adult VirginFemale Spermatheca    5.7 Adult InseminatedFemale Spermatheca    3.9 Adult Ovary    396.1 Adult Testis    17.3 Adult Male Accessory Gland    5.7 Adult Carcass    6.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0030710 expression level Tissue   Expression Level Larval Central Nervous System    216.975 Larval Midgut    6.7 Larval Hindgut    18.1 Larval Malpighian Tubules    5.1 Larval Fat Body    8.1 Larval Salivary Gland    7.6 Larval Trachea    26.65 Larval Carcass no informative data Adult Head    52.4 Adult Eye    30.75 Adult Brain    220.3 Adult Thoracic-Abdominal Ganglion    174.3 Adult Crop    23.8 Adult Midgut    6.6 Adult Hindgut no informative data Adult Malpighian Tubules    5.6 Adult Fat Body    2.6 Adult Salivary Gland    5.1 Adult Heart    5.4 Adult VirginFemale Spermatheca    5.7 Adult InseminatedFemale Spermatheca    3.9 Adult Ovary    396.1 Adult Testis    17.3 Adult Male Accessory Gland    5.7 Adult Carcass    6.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System    216.975 Larval Midgut    6.7 Larval Hindgut    18.1 Larval Malpighian Tubules    5.1 Larval Fat Body    8.1 Larval Salivary Gland    7.6 Larval Trachea    26.65 Larval Carcass no informative data Adult Head    52.4 Adult Eye    30.75 Adult Brain    220.3 Adult Thoracic-Abdominal Ganglion    174.3 Adult Crop    23.8 Adult Midgut    6.6 Adult Hindgut no informative data Adult Malpighian Tubules    5.6 Adult Fat Body    2.6 Adult Salivary Gland    5.1 Adult Heart    5.4 Adult VirginFemale Spermatheca    5.7 Adult InseminatedFemale Spermatheca    3.9 Adult Ovary    396.1 Adult Testis    17.3 Adult Male Accessory Gland    5.7 Adult Carcass    6.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    216.975 Larval Midgut    6.7 Larval Hindgut    18.1 Larval Malpighian Tubules    5.1 Larval Fat Body    8.1 Larval Salivary Gland    7.6 Larval Trachea    26.65 Larval Carcass no informative data Adult Head    52.4 Adult Eye    30.75 Adult Brain    220.3 Adult Thoracic-Abdominal Ganglion    174.3 Adult Crop    23.8 Adult Midgut    6.6 Adult Hindgut no informative data Adult Malpighian Tubules    5.6 Adult Fat Body    2.6 Adult Salivary Gland    5.1 Adult Heart    5.4 Adult VirginFemale Spermatheca    5.7 Adult InseminatedFemale Spermatheca    3.9 Adult Ovary    396.1 Adult Testis    17.3 Adult Male Accessory Gland    5.7 Adult Carcass    6.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    216.975 Larval Midgut    6.7 Larval Hindgut    18.1 Larval Malpighian Tubules    5.1 Larval Fat Body    8.1 Larval Salivary Gland    7.6 Larval Trachea    26.65 Larval Carcass no informative data Adult Head    52.4 Adult Eye    30.75 Adult Brain    220.3 Adult Thoracic-Abdominal Ganglion    174.3 Adult Crop    23.8 Adult Midgut    6.6 Adult Hindgut no informative data Adult Malpighian Tubules    5.6 Adult Fat Body    2.6 Adult Salivary Gland    5.1 Adult Heart    5.4 Adult VirginFemale Spermatheca    5.7 Adult InseminatedFemale Spermatheca    3.9 Adult Ovary    396.1 Adult Testis    17.3 Adult Male Accessory Gland    5.7 Adult Carcass    6.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass no informative data Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut no informative data Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    52.4   NA  Eye    30.75   NA  Brain    220.3   216.975  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    174.3   NA  Crop    23.8   6.7  Midgut    6.6   18.1  Hindgut    no informative data   5.1  Malpighian Tubules    5.6   8.1  Fat Body    2.6   7.6  Salivary Gland    5.1   NA  Heart    5.4   26.65  Trachea    NA   NA  VirginFemale Spermatheca    5.7   NA  InseminatedFemale Spermatheca    3.9   NA  Ovary    396.1   NA  Testis    17.3   NA  Male Accessory Gland    5.7   no informative data  Carcass    6.7 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_17
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030710 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8924-RB
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG8924GD4429 Phenotype manifest in Allele
Classical Alleles ( 3 )
For All Classical Alleles Show
Allele of CG8924 Class Mutagen Stocks Known lesion CG8924e01671 piggyBac transposase 1 -- CG8924EY00245 P-element activity 1 -- CG8924f06425 piggyBac transposase 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG8924 Class Mutagen Stocks Known lesion CG8924GD4429 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG8924GLV21070 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG8924JF02510 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD4429} NA P{TRiP.GLV21070} NA P{TRiP.JF02510} NA
Insertions
	Type of insertions Name Expression data miscellaneous insertions PBac{RB}CG8924e01671 NA PBac{WH}CG8924f06425 NA insertion of mobile activating element P{EPgy2}CG8924EY00245 NA
Gene Ontology: Function, Process & Cellular Component ( 1 unique term )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 1 term )
Molecular Function
CV term Evidence References
DNA binding inferred from electronic annotation with InterPro:IPR011526 (FlyBase Curators et al., 2004-) non-traceable author statement (Lehmann, 2002.7.1)
Biological Process ( 0 terms)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG8924 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 58903 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030710 DroID - A comprehensive database of gene and protein interactions. • FBgn0030710 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32557
Orthologs
Genome-wide drosophilid orthologs	Dana\GF12078 Dere\GG17932 Dgri\GH24177 Dmoj\GI15806 Dpse\GA21412 Dsec\GM22600 Dsim\GD17252 Dvir\GJ18660 Dwil\GK25239 Dyak\GE17239
Curated drosophilid orthologs	Dpse\GA21412
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • XP_395650.1 Apis mellifera (honey bee) BGIBMGA006426-PA Bombyx mori (silk worm) ENSGACP00000015603 Gymnopilus aculeatus (mushroom) XP_001605912.1 Nasonia vitripennis (wasp) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV10144 LH24614 FBgn0234717 FBgn0227198 FBgn0205814 FBgn0188814 FBgn0177470 FBgn0243833 FBgn0081399 FBgn0138555 FBgn0131633 FBgn0110152 FBgn0089117 CPIJ003894 CPIJ003892 GB16366 AGAP002303 PB23578 PHUM366290 PHUM366500 GLEAN_15126
Stocks & Reagents
Stocks Listed in FlyBase ( 7 )
Bloomington	29348 y1 v1; P{TRiP.JF02510}attP2 14821 y1 w67c23 P{EPgy2}CG8924EY00245 35705 y1 sc* v1; P{TRiP.GLV21070}attP2/TM3, Sb1
Harvard	- PBac{RB}CG8924e01671 - PBac{WH}CG8924f06425
VDRC	v48041 w1118; P{GD4429}v48041 v48042 w1118; P{GD4429}v48042
Genomic Clones ( 1 )
	BACR32K23 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 53 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD19131
Other clones	DPiM_LD19131
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM05858 HL01205 LD06053 LD08505 LD13914 LD29820 LD41890 LD46821 RE11347 RE28307 RE37833 RE41305 RE48203 RE49854 RE57488 RE66640
Other clones	7180 30037 45408 50722 53494 59222 62762 65845 65967 153121 156763 178237 193103 214347.24 214373.42 214439.41 525081 CK01.23C.H4 CK01.34A.F6 CK01.100B.A8 EK088925 EK125332 EK161051 EK163417 EK170832 EK176744 EK183343 EK187837 EK259664 EK296445 EN06458 EP01952 EP03832 EP16119 FGC031D04
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030710 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32557
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132863 RefSeq (Proteins) • NP_573091 DDBJ / EMBL / GenBank • AA539852 AAF48544 AAL28808 AAS65373 AW942517 AY061260 BZ286376 BZ286377 CZ479479 CZ489135 CZ489136 Entrez Gene - A searchable database of RefSeq genes. • 32557 UniProtKB/TrEMBL • Q9VXL5
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • BTB/POZ-like (IPR000210) Helix-turn-helix, Psq-like (IPR011526) BTB/POZ (IPR013069) BTB/POZ fold (IPR011333)
Linkouts
	BioGRID - A database of protein and genetic interactions • 58903 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030710 DroID - A comprehensive database of gene and protein interactions. • FBgn0030710 DRSC - Results from RNAi screens. • FBgn0030710 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030710 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG8924-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030710 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32557 InParanoid A subset of ortholog calls from InParanoid. • XP_395650.1 Apis mellifera (honey bee) BGIBMGA006426-PA Bombyx mori (silk worm) ENSGACP00000015603 Gymnopilus aculeatus (mushroom) XP_001605912.1 Nasonia vitripennis (wasp) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32557 modMine - Data generated by the modENCODE project. • FBgn0030710 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • NV10144 LH24614 FBgn0234717 FBgn0227198 FBgn0205814 FBgn0188814 FBgn0177470 FBgn0243833 FBgn0081399 FBgn0138555 FBgn0131633 FBgn0110152 FBgn0089117 CPIJ003894 CPIJ003892 GB16366 AGAP002303 PB23578 PHUM366290 PHUM366500 GLEAN_15126
Synonyms & Secondary IDs ( 1 )
Reported As
Symbol Synonym	CG8924 (Perkins et al., 2009, Haussmann et al., 2008, Ni et al., 2011.7.19)
Name Synonym
Secondary FlyBase IDs
References ( 18 )
Research paper	Haussmann et al., 2008, Genome Biol. 9(4): R73 Erect wing regulates synaptic growth in Drosophila by integration of multiple signaling pathways. [FBrf0209726] Asha et al., 2003, Genetics 163(1): 203--215 Analysis of ras-induced overproliferation in Drosophila hemocytes. [FBrf0155813] Siegmund and Lehmann, 2002, Dev. Genes Evol. 212(3): 152--157 The Drosophila Pipsqueak protein defines a new family of helix-turn-helix DNA-binding proteins. [FBrf0148954]
Supplementary material	The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Personal communication to FlyBase	Ni et al., 2011.7.19, TRiP germline vector pVALIUM21. TRiP germline vector pVALIUM21. [FBrf0214641] Perkins et al., 2009, Update to TRiP stock collection. Update to TRiP stock collection. [FBrf0208864] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215] Lehmann, 2002.7.1, Pipsqueak family. Pipsqueak family. [FBrf0151615]
FlyBase analysis	FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	Gene Disruption Project members and Exelixis, 2005, Genomic mapping of Exelixis insertion collection. Genomic mapping of Exelixis insertion collection. [FBrf0184340] Gene Disruption Project members, 2001-, [title not yet available] [title not yet available] [FBrf0132177] BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]
Curated genome annotation	Lei, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126680]