General Information Symbol Dmel\ CG9172Species D. melanogaster Name Annotation symbol CG9172 Feature type protein_coding_gene FlyBase ID FBgn0030718 Gene Model Status Current Stock availability 4 publicly
available Genomic Location Chromosome (arm) X Recombination map Cytogenetic map 14A5-14A5 Sequence location X:15,879,506..15,880,841 [-]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information This gene is referred to in FlyBase by the symbol
Dmel\CG9172 (FBgn0030718). It is a protein_coding_gene from
Drosophila melanogaster . Based on sequence similarity, it is predicted to have
molecular function : NADH dehydrogenase activity; NADH dehydrogenase (ubiquinone) activity. There is experimental evidence that it is involved in the
biological process : mitochondrial respiratory chain complex I assembly; determination of adult lifespan; response to reactive oxygen species.
4 alleles are reported . The
phenotypes of these alleles are annotated with: trichogen cell; mesothoracic tergum. It has
3 annotated transcripts and
3 annotated polypeptides .
Protein features are: NADH-ubiquinone oxidoreductase, 20 Kd subunit; NADH:ubiquinone oxidoreductase-like, 20kDa subunit; [NiFe]-hydrogenase-3-type complex, small subunit/NADH:quinone oxidoreductase, subunit NuoB. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of high expression. Peak expression observed at stages throughout embryogenesis, during early larval stages, during late pupal stages, in stages of adults of both sexes. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult spermathecae, adult male accessory gland, larval/adult carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval fat body, adult ovary, adult testis. Comments on Affy2 ProbeSet: ProbeSet 1636029_s_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of CG9172. Gene sequence location is
X:15879506..15880841 .
User Contributed Data
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FB2013_03
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Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Gene model reviewed during 5.50
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
- A database of annotated Dmel nuclear genes encoding mitochondrial proteins
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
592.75
Larval Midgut
724.5
Larval Hindgut
932.4
Larval Malpighian Tubules
626.8
Larval Fat Body
358.6
Larval Salivary Gland
715
Larval Trachea
781.35
Larval Carcass
898.025
Adult Head
1316.2
Adult Eye
1877.8
Adult Brain
1066.6
Adult Thoracic-Abdominal Ganglion
1344.9
Adult Crop
939.9
Adult Midgut
1087.3
Adult Hindgut
1560.2
Adult Malpighian Tubules
1064.3
Adult Fat Body
1198.7
Adult Salivary Gland
1035.1
Adult Heart
1526.125
Adult VirginFemale Spermatheca
952.2
Adult InseminatedFemale Spermatheca
865.1
Adult Ovary
466.6
Adult Testis
149
Adult Male Accessory Gland
601.1
Adult Carcass
2425.9
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
(592.75)
Larval Midgut
(724.5)
Larval Hindgut
(932.4)
Larval Malpighian Tubules
(626.8)
Larval Fat Body
358.6
Larval Salivary Gland
(715)
Larval Trachea
(781.35)
Larval Carcass
(898.025)
Adult Head
(1316.2)
Adult Eye
(1877.8)
Adult Brain
(1066.6)
Adult Thoracic-Abdominal Ganglion
(1344.9)
Adult Crop
(939.9)
Adult Midgut
(1087.3)
Adult Hindgut
(1560.2)
Adult Malpighian Tubules
(1064.3)
Adult Fat Body
(1198.7)
Adult Salivary Gland
(1035.1)
Adult Heart
(1526.125)
Adult VirginFemale Spermatheca
(952.2)
Adult InseminatedFemale Spermatheca
(865.1)
Adult Ovary
466.6
Adult Testis
149
Adult Male Accessory Gland
(601.1)
Adult Carcass
(2425.9)
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
592.75
Larval Midgut
724.5
Larval Hindgut
932.4
Larval Malpighian Tubules
626.8
Larval Fat Body
358.6
Larval Salivary Gland
715
Larval Trachea
781.35
Larval Carcass
898.025
Adult Head
(1316.2)
Adult Eye
(1877.8)
Adult Brain
1066.6
Adult Thoracic-Abdominal Ganglion
(1344.9)
Adult Crop
939.9
Adult Midgut
(1087.3)
Adult Hindgut
(1560.2)
Adult Malpighian Tubules
1064.3
Adult Fat Body
(1198.7)
Adult Salivary Gland
1035.1
Adult Heart
(1526.125)
Adult VirginFemale Spermatheca
952.2
Adult InseminatedFemale Spermatheca
865.1
Adult Ovary
466.6
Adult Testis
149
Adult Male Accessory Gland
601.1
Adult Carcass
(2425.9)
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
592.75
Larval Midgut
724.5
Larval Hindgut
932.4
Larval Malpighian Tubules
626.8
Larval Fat Body
358.6
Larval Salivary Gland
715
Larval Trachea
781.35
Larval Carcass
898.025
Adult Head
1316.2
Adult Eye
1877.8
Adult Brain
1066.6
Adult Thoracic-Abdominal Ganglion
1344.9
Adult Crop
939.9
Adult Midgut
1087.3
Adult Hindgut
1560.2
Adult Malpighian Tubules
1064.3
Adult Fat Body
1198.7
Adult Salivary Gland
1035.1
Adult Heart
1526.125
Adult VirginFemale Spermatheca
952.2
Adult InseminatedFemale Spermatheca
865.1
Adult Ovary
466.6
Adult Testis
149
Adult Male Accessory Gland
601.1
Adult Carcass
2425.9
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
592.75
Larval Midgut
724.5
Larval Hindgut
932.4
Larval Malpighian Tubules
626.8
Larval Fat Body
358.6
Larval Salivary Gland
715
Larval Trachea
781.35
Larval Carcass
898.025
Adult Head
1316.2
Adult Eye
1877.8
Adult Brain
1066.6
Adult Thoracic-Abdominal Ganglion
1344.9
Adult Crop
939.9
Adult Midgut
1087.3
Adult Hindgut
1560.2
Adult Malpighian Tubules
1064.3
Adult Fat Body
1198.7
Adult Salivary Gland
1035.1
Adult Heart
1526.125
Adult VirginFemale Spermatheca
952.2
Adult InseminatedFemale Spermatheca
865.1
Adult Ovary
466.6
Adult Testis
149
Adult Male Accessory Gland
601.1
Adult Carcass
2425.9
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
592.75
Larval Midgut
724.5
Larval Hindgut
(932.4)
Larval Malpighian Tubules
626.8
Larval Fat Body
358.6
Larval Salivary Gland
715
Larval Trachea
781.35
Larval Carcass
(898.025)
Adult Head
(1316.2)
Adult Eye
(1877.8)
Adult Brain
(1066.6)
Adult Thoracic-Abdominal Ganglion
(1344.9)
Adult Crop
(939.9)
Adult Midgut
(1087.3)
Adult Hindgut
(1560.2)
Adult Malpighian Tubules
(1064.3)
Adult Fat Body
(1198.7)
Adult Salivary Gland
(1035.1)
Adult Heart
(1526.125)
Adult VirginFemale Spermatheca
(952.2)
Adult InseminatedFemale Spermatheca
(865.1)
Adult Ovary
466.6
Adult Testis
149
Adult Male Accessory Gland
601.1
Adult Carcass
(2425.9)
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
592.75
Larval Midgut
724.5
Larval Hindgut
932.4
Larval Malpighian Tubules
626.8
Larval Fat Body
358.6
Larval Salivary Gland
715
Larval Trachea
781.35
Larval Carcass
898.025
Adult Head
1316.2
Adult Eye
(1877.8)
Adult Brain
1066.6
Adult Thoracic-Abdominal Ganglion
1344.9
Adult Crop
939.9
Adult Midgut
1087.3
Adult Hindgut
1560.2
Adult Malpighian Tubules
1064.3
Adult Fat Body
1198.7
Adult Salivary Gland
1035.1
Adult Heart
1526.125
Adult VirginFemale Spermatheca
952.2
Adult InseminatedFemale Spermatheca
865.1
Adult Ovary
466.6
Adult Testis
149
Adult Male Accessory Gland
601.1
Adult Carcass
(2425.9)
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
592.75
Larval Midgut
724.5
Larval Hindgut
932.4
Larval Malpighian Tubules
626.8
Larval Fat Body
358.6
Larval Salivary Gland
715
Larval Trachea
781.35
Larval Carcass
898.025
Adult Head
1316.2
Adult Eye
1877.8
Adult Brain
1066.6
Adult Thoracic-Abdominal Ganglion
1344.9
Adult Crop
939.9
Adult Midgut
1087.3
Adult Hindgut
1560.2
Adult Malpighian Tubules
1064.3
Adult Fat Body
1198.7
Adult Salivary Gland
1035.1
Adult Heart
1526.125
Adult VirginFemale Spermatheca
952.2
Adult InseminatedFemale Spermatheca
865.1
Adult Ovary
466.6
Adult Testis
149
Adult Male Accessory Gland
601.1
Adult Carcass
2425.9
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
1316.2
NA
Eye
1877.8
NA
Brain
1066.6
592.75
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
1344.9
NA
Crop
939.9
724.5
Midgut
1087.3
932.4
Hindgut
1560.2
626.8
Malpighian Tubules
1064.3
358.6
Fat Body
1198.7
715
Salivary Gland
1035.1
NA
Heart
1526.125
781.35
Trachea
NA
NA
VirginFemale Spermatheca
952.2
NA
InseminatedFemale Spermatheca
865.1
NA
Ovary
466.6
NA
Testis
149
NA
Male Accessory Gland
601.1
898.025
Carcass
2425.9
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
39
central nervous system, larvae L3
22
central nervous system, pupae P8
23
head, virgin 1-day female
73
head, virgin 4-day female
50
head, virgin 20-day female
58
head, mated 1-day female
50
head, mated 4-day female
34
head, mated 20-day female
42
head, mated 1-day male
84
head, mated 4-day male
54
head, mated 20-day male
63
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
16
digestive system, larvae L3 wandering
27
digestive system, 1-day adult
46
digestive system, 4-day adult
29
digestive system, 20-day adult
30
fat body, larvae L3 wandering
8
fat body, white prepupae
10
fat body, pupae P8
24
carcass, larvae L3 wandering
20
carcass, 1-day adult
129
carcass, 4-day adult
78
carcass, 20-day adult
97
ovary, virgin 4-day female
32
ovary, mated 4-day female
23
testis, mated 4-day male
20
accessory gland, mated 4-day male
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(39)
central nervous system, larvae L3
22
central nervous system, pupae P8
23
head, virgin 1-day female
(73)
head, virgin 4-day female
(50)
head, virgin 20-day female
(58)
head, mated 1-day female
(50)
head, mated 4-day female
(34)
head, mated 20-day female
(42)
head, mated 1-day male
(84)
head, mated 4-day male
(54)
head, mated 20-day male
(63)
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
16
digestive system, larvae L3 wandering
(27)
digestive system, 1-day adult
(46)
digestive system, 4-day adult
(29)
digestive system, 20-day adult
(30)
fat body, larvae L3 wandering
8
fat body, white prepupae
10
fat body, pupae P8
24
carcass, larvae L3 wandering
20
carcass, 1-day adult
(129)
carcass, 4-day adult
(78)
carcass, 20-day adult
(97)
ovary, virgin 4-day female
(32)
ovary, mated 4-day female
23
testis, mated 4-day male
20
accessory gland, mated 4-day male
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
39
central nervous system, larvae L3
22
central nervous system, pupae P8
23
head, virgin 1-day female
73
head, virgin 4-day female
50
head, virgin 20-day female
58
head, mated 1-day female
50
head, mated 4-day female
34
head, mated 20-day female
42
head, mated 1-day male
84
head, mated 4-day male
54
head, mated 20-day male
63
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
16
digestive system, larvae L3 wandering
27
digestive system, 1-day adult
46
digestive system, 4-day adult
29
digestive system, 20-day adult
30
fat body, larvae L3 wandering
8
fat body, white prepupae
10
fat body, pupae P8
24
carcass, larvae L3 wandering
20
carcass, 1-day adult
(129)
carcass, 4-day adult
78
carcass, 20-day adult
97
ovary, virgin 4-day female
32
ovary, mated 4-day female
23
testis, mated 4-day male
20
accessory gland, mated 4-day male
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
39
central nervous system, larvae L3
22
central nervous system, pupae P8
23
head, virgin 1-day female
73
head, virgin 4-day female
50
head, virgin 20-day female
58
head, mated 1-day female
50
head, mated 4-day female
34
head, mated 20-day female
42
head, mated 1-day male
84
head, mated 4-day male
54
head, mated 20-day male
63
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
16
digestive system, larvae L3 wandering
27
digestive system, 1-day adult
46
digestive system, 4-day adult
29
digestive system, 20-day adult
30
fat body, larvae L3 wandering
8
fat body, white prepupae
10
fat body, pupae P8
24
carcass, larvae L3 wandering
20
carcass, 1-day adult
129
carcass, 4-day adult
78
carcass, 20-day adult
97
ovary, virgin 4-day female
32
ovary, mated 4-day female
23
testis, mated 4-day male
20
accessory gland, mated 4-day male
22
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
39
central nervous system, larvae L3
22
central nervous system, pupae P8
23
head, virgin 1-day female
73
head, virgin 4-day female
50
head, virgin 20-day female
58
head, mated 1-day female
50
head, mated 4-day female
34
head, mated 20-day female
42
head, mated 1-day male
84
head, mated 4-day male
54
head, mated 20-day male
63
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
16
digestive system, larvae L3 wandering
27
digestive system, 1-day adult
46
digestive system, 4-day adult
29
digestive system, 20-day adult
30
fat body, larvae L3 wandering
8
fat body, white prepupae
10
fat body, pupae P8
24
carcass, larvae L3 wandering
20
carcass, 1-day adult
129
carcass, 4-day adult
78
carcass, 20-day adult
97
ovary, virgin 4-day female
32
ovary, mated 4-day female
23
testis, mated 4-day male
20
accessory gland, mated 4-day male
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(39)
central nervous system, larvae L3
22
central nervous system, pupae P8
23
head, virgin 1-day female
(73)
head, virgin 4-day female
(50)
head, virgin 20-day female
(58)
head, mated 1-day female
(50)
head, mated 4-day female
(34)
head, mated 20-day female
(42)
head, mated 1-day male
(84)
head, mated 4-day male
(54)
head, mated 20-day male
(63)
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
16
digestive system, larvae L3 wandering
27
digestive system, 1-day adult
(46)
digestive system, 4-day adult
29
digestive system, 20-day adult
30
fat body, larvae L3 wandering
8
fat body, white prepupae
10
fat body, pupae P8
24
carcass, larvae L3 wandering
20
carcass, 1-day adult
(129)
carcass, 4-day adult
(78)
carcass, 20-day adult
(97)
ovary, virgin 4-day female
32
ovary, mated 4-day female
23
testis, mated 4-day male
20
accessory gland, mated 4-day male
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
39
central nervous system, larvae L3
22
central nervous system, pupae P8
23
head, virgin 1-day female
73
head, virgin 4-day female
50
head, virgin 20-day female
58
head, mated 1-day female
50
head, mated 4-day female
34
head, mated 20-day female
42
head, mated 1-day male
84
head, mated 4-day male
54
head, mated 20-day male
63
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
16
digestive system, larvae L3 wandering
27
digestive system, 1-day adult
46
digestive system, 4-day adult
29
digestive system, 20-day adult
30
fat body, larvae L3 wandering
8
fat body, white prepupae
10
fat body, pupae P8
24
carcass, larvae L3 wandering
20
carcass, 1-day adult
129
carcass, 4-day adult
78
carcass, 20-day adult
97
ovary, virgin 4-day female
32
ovary, mated 4-day female
23
testis, mated 4-day male
20
accessory gland, mated 4-day male
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
39
central nervous system, larvae L3
22
central nervous system, pupae P8
23
head, virgin 1-day female
73
head, virgin 4-day female
50
head, virgin 20-day female
58
head, mated 1-day female
50
head, mated 4-day female
34
head, mated 20-day female
42
head, mated 1-day male
84
head, mated 4-day male
54
head, mated 20-day male
63
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
16
digestive system, larvae L3 wandering
27
digestive system, 1-day adult
46
digestive system, 4-day adult
29
digestive system, 20-day adult
30
fat body, larvae L3 wandering
8
fat body, white prepupae
10
fat body, pupae P8
24
carcass, larvae L3 wandering
20
carcass, 1-day adult
129
carcass, 4-day adult
78
carcass, 20-day adult
97
ovary, virgin 4-day female
32
ovary, mated 4-day female
23
testis, mated 4-day male
20
accessory gland, mated 4-day male
22
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
83
embryo 02-04hr
100
embryo 04-06hr
78
embryo 06-08hr
80
embryo 08-10hr
89
embryo 10-12hr
115
embryo 12-14hr
82
embryo 14-16hr
146
embryo 16-18hr
142
embryo 18-20hr
141
embryo 20-22hr
141
embryo 22-24hr
141
larva L1
196
larva L2
161
larva L3 12hr old
143
larva L3 puffstage 1-2
79
larva L3 puffstage 3-6
55
larva L3 puffstage 7-9
55
white prepupae new
50
white prepupae 12hr
46
white prepupae 24hr
51
pupae 2d postWPP
76
pupae 3d postWPP
183
pupae 4d postWPP
331
adult male 01day
262
adult male 05day
247
adult male 30day
175
adult female 01day
298
adult female 05day
110
adult female 30day
91
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(83)
embryo 02-04hr
(100)
embryo 04-06hr
(78)
embryo 06-08hr
(80)
embryo 08-10hr
(89)
embryo 10-12hr
(115)
embryo 12-14hr
(82)
embryo 14-16hr
(146)
embryo 16-18hr
(142)
embryo 18-20hr
(141)
embryo 20-22hr
(141)
embryo 22-24hr
(141)
larva L1
(196)
larva L2
(161)
larva L3 12hr old
(143)
larva L3 puffstage 1-2
(79)
larva L3 puffstage 3-6
(55)
larva L3 puffstage 7-9
(55)
white prepupae new
(50)
white prepupae 12hr
(46)
white prepupae 24hr
(51)
pupae 2d postWPP
(76)
pupae 3d postWPP
(183)
pupae 4d postWPP
(331)
adult male 01day
(262)
adult male 05day
(247)
adult male 30day
(175)
adult female 01day
(298)
adult female 05day
(110)
adult female 30day
(91)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
83
embryo 02-04hr
100
embryo 04-06hr
78
embryo 06-08hr
80
embryo 08-10hr
89
embryo 10-12hr
(115)
embryo 12-14hr
82
embryo 14-16hr
(146)
embryo 16-18hr
(142)
embryo 18-20hr
(141)
embryo 20-22hr
(141)
embryo 22-24hr
(141)
larva L1
(196)
larva L2
(161)
larva L3 12hr old
(143)
larva L3 puffstage 1-2
79
larva L3 puffstage 3-6
55
larva L3 puffstage 7-9
55
white prepupae new
50
white prepupae 12hr
46
white prepupae 24hr
51
pupae 2d postWPP
76
pupae 3d postWPP
(183)
pupae 4d postWPP
(331)
adult male 01day
(262)
adult male 05day
(247)
adult male 30day
(175)
adult female 01day
(298)
adult female 05day
(110)
adult female 30day
91
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
83
embryo 02-04hr
100
embryo 04-06hr
78
embryo 06-08hr
80
embryo 08-10hr
89
embryo 10-12hr
115
embryo 12-14hr
82
embryo 14-16hr
146
embryo 16-18hr
142
embryo 18-20hr
141
embryo 20-22hr
141
embryo 22-24hr
141
larva L1
196
larva L2
161
larva L3 12hr old
143
larva L3 puffstage 1-2
79
larva L3 puffstage 3-6
55
larva L3 puffstage 7-9
55
white prepupae new
50
white prepupae 12hr
46
white prepupae 24hr
51
pupae 2d postWPP
76
pupae 3d postWPP
183
pupae 4d postWPP
331
adult male 01day
262
adult male 05day
247
adult male 30day
175
adult female 01day
298
adult female 05day
110
adult female 30day
91
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
83
embryo 02-04hr
100
embryo 04-06hr
78
embryo 06-08hr
80
embryo 08-10hr
89
embryo 10-12hr
115
embryo 12-14hr
82
embryo 14-16hr
146
embryo 16-18hr
142
embryo 18-20hr
141
embryo 20-22hr
141
embryo 22-24hr
141
larva L1
196
larva L2
161
larva L3 12hr old
143
larva L3 puffstage 1-2
79
larva L3 puffstage 3-6
55
larva L3 puffstage 7-9
55
white prepupae new
50
white prepupae 12hr
46
white prepupae 24hr
51
pupae 2d postWPP
76
pupae 3d postWPP
183
pupae 4d postWPP
331
adult male 01day
262
adult male 05day
247
adult male 30day
175
adult female 01day
298
adult female 05day
110
adult female 30day
91
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
(83)
embryo 02-04hr
(100)
embryo 04-06hr
(78)
embryo 06-08hr
(80)
embryo 08-10hr
(89)
embryo 10-12hr
(115)
embryo 12-14hr
(82)
embryo 14-16hr
(146)
embryo 16-18hr
(142)
embryo 18-20hr
(141)
embryo 20-22hr
(141)
embryo 22-24hr
(141)
larva L1
(196)
larva L2
(161)
larva L3 12hr old
(143)
larva L3 puffstage 1-2
(79)
larva L3 puffstage 3-6
(55)
larva L3 puffstage 7-9
(55)
white prepupae new
(50)
white prepupae 12hr
(46)
white prepupae 24hr
(51)
pupae 2d postWPP
(76)
pupae 3d postWPP
(183)
pupae 4d postWPP
(331)
adult male 01day
(262)
adult male 05day
(247)
adult male 30day
(175)
adult female 01day
(298)
adult female 05day
(110)
adult female 30day
(91)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
83
embryo 02-04hr
100
embryo 04-06hr
78
embryo 06-08hr
80
embryo 08-10hr
89
embryo 10-12hr
115
embryo 12-14hr
82
embryo 14-16hr
(146)
embryo 16-18hr
142
embryo 18-20hr
141
embryo 20-22hr
141
embryo 22-24hr
141
larva L1
(196)
larva L2
(161)
larva L3 12hr old
143
larva L3 puffstage 1-2
79
larva L3 puffstage 3-6
55
larva L3 puffstage 7-9
55
white prepupae new
50
white prepupae 12hr
46
white prepupae 24hr
51
pupae 2d postWPP
76
pupae 3d postWPP
(183)
pupae 4d postWPP
(331)
adult male 01day
(262)
adult male 05day
(247)
adult male 30day
(175)
adult female 01day
(298)
adult female 05day
110
adult female 30day
91
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
83
embryo 02-04hr
100
embryo 04-06hr
78
embryo 06-08hr
80
embryo 08-10hr
89
embryo 10-12hr
115
embryo 12-14hr
82
embryo 14-16hr
146
embryo 16-18hr
142
embryo 18-20hr
141
embryo 20-22hr
141
embryo 22-24hr
141
larva L1
196
larva L2
161
larva L3 12hr old
143
larva L3 puffstage 1-2
79
larva L3 puffstage 3-6
55
larva L3 puffstage 7-9
55
white prepupae new
50
white prepupae 12hr
46
white prepupae 24hr
51
pupae 2d postWPP
76
pupae 3d postWPP
183
pupae 4d postWPP
331
adult male 01day
262
adult male 05day
247
adult male 30day
175
adult female 01day
298
adult female 05day
110
adult female 30day
91
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
58
Schneider line 2 Sg4
69
embryonic 1182-4H
44
embryonic GM2
42
embryonic Kc167
60
embryonic S1
112
embryonic S3
58
leg disc CME L1
33
wing disc CME-W2
44
wing disc ML-DmD8
54
wing disc ML-DmD9
60
wing disc ML-DmD16-c3
32
wing disc ML-DmD21
76
wing disc ML-DmD32
34
haltere disc ML-DmD17-c3
56
eye-antennal disc ML-DmD11
76
antennal disc ML-DmD20-c5
50
mixed discs ML-DmD4-c1
28
CNS ML-DmBG1-c1
38
CNS ML-DmBG2-c2
27
tumorous blood cells mbn2
43
ovary fGS/OSS
25
ovary OSC
29
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(58)
Schneider line 2 Sg4
(69)
embryonic 1182-4H
(44)
embryonic GM2
(42)
embryonic Kc167
(60)
embryonic S1
(112)
embryonic S3
(58)
leg disc CME L1
(33)
wing disc CME-W2
(44)
wing disc ML-DmD8
(54)
wing disc ML-DmD9
(60)
wing disc ML-DmD16-c3
(32)
wing disc ML-DmD21
(76)
wing disc ML-DmD32
(34)
haltere disc ML-DmD17-c3
(56)
eye-antennal disc ML-DmD11
(76)
antennal disc ML-DmD20-c5
(50)
mixed discs ML-DmD4-c1
(28)
CNS ML-DmBG1-c1
(38)
CNS ML-DmBG2-c2
(27)
tumorous blood cells mbn2
(43)
ovary fGS/OSS
25
ovary OSC
(29)
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
58
Schneider line 2 Sg4
69
embryonic 1182-4H
44
embryonic GM2
42
embryonic Kc167
60
embryonic S1
(112)
embryonic S3
58
leg disc CME L1
33
wing disc CME-W2
44
wing disc ML-DmD8
54
wing disc ML-DmD9
60
wing disc ML-DmD16-c3
32
wing disc ML-DmD21
76
wing disc ML-DmD32
34
haltere disc ML-DmD17-c3
56
eye-antennal disc ML-DmD11
76
antennal disc ML-DmD20-c5
50
mixed discs ML-DmD4-c1
28
CNS ML-DmBG1-c1
38
CNS ML-DmBG2-c2
27
tumorous blood cells mbn2
43
ovary fGS/OSS
25
ovary OSC
29
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
58
Schneider line 2 Sg4
69
embryonic 1182-4H
44
embryonic GM2
42
embryonic Kc167
60
embryonic S1
112
embryonic S3
58
leg disc CME L1
33
wing disc CME-W2
44
wing disc ML-DmD8
54
wing disc ML-DmD9
60
wing disc ML-DmD16-c3
32
wing disc ML-DmD21
76
wing disc ML-DmD32
34
haltere disc ML-DmD17-c3
56
eye-antennal disc ML-DmD11
76
antennal disc ML-DmD20-c5
50
mixed discs ML-DmD4-c1
28
CNS ML-DmBG1-c1
38
CNS ML-DmBG2-c2
27
tumorous blood cells mbn2
43
ovary fGS/OSS
25
ovary OSC
29
ovary OSS
11
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
58
Schneider line 2 Sg4
69
embryonic 1182-4H
44
embryonic GM2
42
embryonic Kc167
60
embryonic S1
112
embryonic S3
58
leg disc CME L1
33
wing disc CME-W2
44
wing disc ML-DmD8
54
wing disc ML-DmD9
60
wing disc ML-DmD16-c3
32
wing disc ML-DmD21
76
wing disc ML-DmD32
34
haltere disc ML-DmD17-c3
56
eye-antennal disc ML-DmD11
76
antennal disc ML-DmD20-c5
50
mixed discs ML-DmD4-c1
28
CNS ML-DmBG1-c1
38
CNS ML-DmBG2-c2
27
tumorous blood cells mbn2
43
ovary fGS/OSS
25
ovary OSC
29
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(58)
Schneider line 2 Sg4
(69)
embryonic 1182-4H
(44)
embryonic GM2
(42)
embryonic Kc167
(60)
embryonic S1
(112)
embryonic S3
(58)
leg disc CME L1
(33)
wing disc CME-W2
(44)
wing disc ML-DmD8
(54)
wing disc ML-DmD9
(60)
wing disc ML-DmD16-c3
32
wing disc ML-DmD21
(76)
wing disc ML-DmD32
(34)
haltere disc ML-DmD17-c3
(56)
eye-antennal disc ML-DmD11
(76)
antennal disc ML-DmD20-c5
(50)
mixed discs ML-DmD4-c1
28
CNS ML-DmBG1-c1
(38)
CNS ML-DmBG2-c2
27
tumorous blood cells mbn2
(43)
ovary fGS/OSS
25
ovary OSC
29
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
58
Schneider line 2 Sg4
69
embryonic 1182-4H
44
embryonic GM2
42
embryonic Kc167
60
embryonic S1
112
embryonic S3
58
leg disc CME L1
33
wing disc CME-W2
44
wing disc ML-DmD8
54
wing disc ML-DmD9
60
wing disc ML-DmD16-c3
32
wing disc ML-DmD21
76
wing disc ML-DmD32
34
haltere disc ML-DmD17-c3
56
eye-antennal disc ML-DmD11
76
antennal disc ML-DmD20-c5
50
mixed discs ML-DmD4-c1
28
CNS ML-DmBG1-c1
38
CNS ML-DmBG2-c2
27
tumorous blood cells mbn2
43
ovary fGS/OSS
25
ovary OSC
29
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
58
Schneider line 2 Sg4
69
embryonic 1182-4H
44
embryonic GM2
42
embryonic Kc167
60
embryonic S1
112
embryonic S3
58
leg disc CME L1
33
wing disc CME-W2
44
wing disc ML-DmD8
54
wing disc ML-DmD9
60
wing disc ML-DmD16-c3
32
wing disc ML-DmD21
76
wing disc ML-DmD32
34
haltere disc ML-DmD17-c3
56
eye-antennal disc ML-DmD11
76
antennal disc ML-DmD20-c5
50
mixed discs ML-DmD4-c1
28
CNS ML-DmBG1-c1
38
CNS ML-DmBG2-c2
27
tumorous blood cells mbn2
43
ovary fGS/OSS
25
ovary OSC
29
ovary OSS
11
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
22
cold shock, 4-day adult
17
heat shock, 4-day adult
57
Cadmium 50 mM 6 hrs, larvae L3
64
Cadmium 50 mM 12 hrs, larvae L3
51
Cadmium 50 mM 48 hrs, 4-day adult
50
Cadmium 100 mM 48 hrs, 4-day adult
42
Copper 0.5 mM 12 hrs, larvae L3
19
Copper 15 mM 48 hrs, 4-day adult
17
Zinc 5 mM 12 hrs, larvae L3
24
Zinc 4.5 mM 48 hrs, 4-day adult
35
Ethanol 2.5% 3 hrs, larvae L3
69
Ethanol 5% 3 hrs, larvae L3
78
Ethanol 10% 3 hrs, larvae L3
67
Caffeine 1.5 mg/ml 4 hrs, larvae L3
71
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
44
Caffeine 25 mg/ml 48 hrs, 4-day adult
19
Paraquat 5 mM 48 hrs, 4-day adult
72
Paraquat 10 mM 48 hrs, 4-day adult
72
Rotenone 2 μg 12 hrs, larvae L3
90
Rotenone 8 μg 12 hrs, larvae L3
108
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
22
cold shock, 4-day adult
17
heat shock, 4-day adult
(57)
Cadmium 50 mM 6 hrs, larvae L3
(64)
Cadmium 50 mM 12 hrs, larvae L3
(51)
Cadmium 50 mM 48 hrs, 4-day adult
(50)
Cadmium 100 mM 48 hrs, 4-day adult
(42)
Copper 0.5 mM 12 hrs, larvae L3
19
Copper 15 mM 48 hrs, 4-day adult
17
Zinc 5 mM 12 hrs, larvae L3
24
Zinc 4.5 mM 48 hrs, 4-day adult
(35)
Ethanol 2.5% 3 hrs, larvae L3
(69)
Ethanol 5% 3 hrs, larvae L3
(78)
Ethanol 10% 3 hrs, larvae L3
(67)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(71)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(44)
Caffeine 25 mg/ml 48 hrs, 4-day adult
19
Paraquat 5 mM 48 hrs, 4-day adult
(72)
Paraquat 10 mM 48 hrs, 4-day adult
(72)
Rotenone 2 μg 12 hrs, larvae L3
(90)
Rotenone 8 μg 12 hrs, larvae L3
(108)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
22
cold shock, 4-day adult
17
heat shock, 4-day adult
57
Cadmium 50 mM 6 hrs, larvae L3
64
Cadmium 50 mM 12 hrs, larvae L3
51
Cadmium 50 mM 48 hrs, 4-day adult
50
Cadmium 100 mM 48 hrs, 4-day adult
42
Copper 0.5 mM 12 hrs, larvae L3
19
Copper 15 mM 48 hrs, 4-day adult
17
Zinc 5 mM 12 hrs, larvae L3
24
Zinc 4.5 mM 48 hrs, 4-day adult
35
Ethanol 2.5% 3 hrs, larvae L3
69
Ethanol 5% 3 hrs, larvae L3
78
Ethanol 10% 3 hrs, larvae L3
67
Caffeine 1.5 mg/ml 4 hrs, larvae L3
71
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
44
Caffeine 25 mg/ml 48 hrs, 4-day adult
19
Paraquat 5 mM 48 hrs, 4-day adult
72
Paraquat 10 mM 48 hrs, 4-day adult
72
Rotenone 2 μg 12 hrs, larvae L3
90
Rotenone 8 μg 12 hrs, larvae L3
(108)
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
22
cold shock, 4-day adult
17
heat shock, 4-day adult
57
Cadmium 50 mM 6 hrs, larvae L3
64
Cadmium 50 mM 12 hrs, larvae L3
51
Cadmium 50 mM 48 hrs, 4-day adult
50
Cadmium 100 mM 48 hrs, 4-day adult
42
Copper 0.5 mM 12 hrs, larvae L3
19
Copper 15 mM 48 hrs, 4-day adult
17
Zinc 5 mM 12 hrs, larvae L3
24
Zinc 4.5 mM 48 hrs, 4-day adult
35
Ethanol 2.5% 3 hrs, larvae L3
69
Ethanol 5% 3 hrs, larvae L3
78
Ethanol 10% 3 hrs, larvae L3
67
Caffeine 1.5 mg/ml 4 hrs, larvae L3
71
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
44
Caffeine 25 mg/ml 48 hrs, 4-day adult
19
Paraquat 5 mM 48 hrs, 4-day adult
72
Paraquat 10 mM 48 hrs, 4-day adult
72
Rotenone 2 μg 12 hrs, larvae L3
90
Rotenone 8 μg 12 hrs, larvae L3
108
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
22
cold shock, 4-day adult
17
heat shock, 4-day adult
57
Cadmium 50 mM 6 hrs, larvae L3
64
Cadmium 50 mM 12 hrs, larvae L3
51
Cadmium 50 mM 48 hrs, 4-day adult
50
Cadmium 100 mM 48 hrs, 4-day adult
42
Copper 0.5 mM 12 hrs, larvae L3
19
Copper 15 mM 48 hrs, 4-day adult
17
Zinc 5 mM 12 hrs, larvae L3
24
Zinc 4.5 mM 48 hrs, 4-day adult
35
Ethanol 2.5% 3 hrs, larvae L3
69
Ethanol 5% 3 hrs, larvae L3
78
Ethanol 10% 3 hrs, larvae L3
67
Caffeine 1.5 mg/ml 4 hrs, larvae L3
71
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
44
Caffeine 25 mg/ml 48 hrs, 4-day adult
19
Paraquat 5 mM 48 hrs, 4-day adult
72
Paraquat 10 mM 48 hrs, 4-day adult
72
Rotenone 2 μg 12 hrs, larvae L3
90
Rotenone 8 μg 12 hrs, larvae L3
108
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
22
cold shock, 4-day adult
17
heat shock, 4-day adult
(57)
Cadmium 50 mM 6 hrs, larvae L3
(64)
Cadmium 50 mM 12 hrs, larvae L3
(51)
Cadmium 50 mM 48 hrs, 4-day adult
(50)
Cadmium 100 mM 48 hrs, 4-day adult
(42)
Copper 0.5 mM 12 hrs, larvae L3
19
Copper 15 mM 48 hrs, 4-day adult
17
Zinc 5 mM 12 hrs, larvae L3
24
Zinc 4.5 mM 48 hrs, 4-day adult
(35)
Ethanol 2.5% 3 hrs, larvae L3
(69)
Ethanol 5% 3 hrs, larvae L3
(78)
Ethanol 10% 3 hrs, larvae L3
(67)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
(71)
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
(44)
Caffeine 25 mg/ml 48 hrs, 4-day adult
19
Paraquat 5 mM 48 hrs, 4-day adult
(72)
Paraquat 10 mM 48 hrs, 4-day adult
(72)
Rotenone 2 μg 12 hrs, larvae L3
(90)
Rotenone 8 μg 12 hrs, larvae L3
(108)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
22
cold shock, 4-day adult
17
heat shock, 4-day adult
57
Cadmium 50 mM 6 hrs, larvae L3
64
Cadmium 50 mM 12 hrs, larvae L3
51
Cadmium 50 mM 48 hrs, 4-day adult
50
Cadmium 100 mM 48 hrs, 4-day adult
42
Copper 0.5 mM 12 hrs, larvae L3
19
Copper 15 mM 48 hrs, 4-day adult
17
Zinc 5 mM 12 hrs, larvae L3
24
Zinc 4.5 mM 48 hrs, 4-day adult
35
Ethanol 2.5% 3 hrs, larvae L3
69
Ethanol 5% 3 hrs, larvae L3
78
Ethanol 10% 3 hrs, larvae L3
67
Caffeine 1.5 mg/ml 4 hrs, larvae L3
71
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
44
Caffeine 25 mg/ml 48 hrs, 4-day adult
19
Paraquat 5 mM 48 hrs, 4-day adult
72
Paraquat 10 mM 48 hrs, 4-day adult
72
Rotenone 2 μg 12 hrs, larvae L3
90
Rotenone 8 μg 12 hrs, larvae L3
108
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
22
cold shock, 4-day adult
17
heat shock, 4-day adult
57
Cadmium 50 mM 6 hrs, larvae L3
64
Cadmium 50 mM 12 hrs, larvae L3
51
Cadmium 50 mM 48 hrs, 4-day adult
50
Cadmium 100 mM 48 hrs, 4-day adult
42
Copper 0.5 mM 12 hrs, larvae L3
19
Copper 15 mM 48 hrs, 4-day adult
17
Zinc 5 mM 12 hrs, larvae L3
24
Zinc 4.5 mM 48 hrs, 4-day adult
35
Ethanol 2.5% 3 hrs, larvae L3
69
Ethanol 5% 3 hrs, larvae L3
78
Ethanol 10% 3 hrs, larvae L3
67
Caffeine 1.5 mg/ml 4 hrs, larvae L3
71
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
44
Caffeine 25 mg/ml 48 hrs, 4-day adult
19
Paraquat 5 mM 48 hrs, 4-day adult
72
Paraquat 10 mM 48 hrs, 4-day adult
72
Rotenone 2 μg 12 hrs, larvae L3
90
Rotenone 8 μg 12 hrs, larvae L3
108
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 0 ) For All Classical Alleles Show Allele of
CG9172 Class Mutagen Stocks Known lesion
Alleles Carried on Transgenic Constructs
( 4 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Transgenic Constructs & Insertions
Transgenic Constructs Insertions Gene Ontology: Function, Process
& Cellular Component ( 9 unique terms ) Terms Based on
Experimental Evidence ( 3 terms ) Molecular Function ( 0 terms) Biological Process inferred from mutant phenotype
inferred from mutant phenotype
inferred from mutant phenotype
Cellular Component ( 0 terms) Terms Based on Predictions or
Assertions ( 6 terms ) Molecular Function Biological Process Cellular Component Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting, experimental knowledge based
experimental knowledge based, anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
experimental knowledge based
experimental knowledge based
experimental knowledge based
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (39)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG6FJ8W6 )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans
(EOG632177 )
Aedes aegypti
Yellow fever mosquito
Y
Anopheles gambiae
Malaria mosquito
Y
Culex quinquefasciatus
Southern house mosquito
Y
Orthologs in non-Dipteran Insects
(EOG6NVXGH )
Apis mellifera
Western honey bee
Amel\GB48163
Y
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG035203
Y
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\nuoB
Y
Atta cephalotes
Leafcutter ant
Acep\nuoB
Y
Camponotus floridanus
Florida carpenter ant
Cflo\nuoB
Y
Harpegnathos saltator
Jerdons jumping ant
Hsal\nuoB
Y
Linepithema humile
Argentine ant
Lhum\LH22162
Y
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB15629
Y
Solenopsis invicta
Red fire ant
Sinv\SINV16126
Y
Acyrthosiphon pisum
Pea aphid
Y
Pediculus humanus
Human body louse
Y
Tribolium castaneum
Red flour beetle
Y
Tribolium castaneum
Red flour beetle
Y
Orthologs in non-Insect Arthropods
(EOG69GHZQ )
Daphnia pulex
Water flea
Y
Ixodes scapularis
Deer tick
Y
Orthologs in non-Arthropod Metazoa
(EOG6SNDH6 )
Caenorhabditis elegans
Nematode
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Xenopus tropicalis
Western clawed frog
Y
Gallus gallus
Domestic chicken
Y
Mus musculus
House mouse
Y
Rattus norvegicus
Norway rat
Y
Human Orthologs (1)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 4 )VDRC Genomic Clones ( 1 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 233 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for database merge of Additional comments The
CG2014 gene may have been derived from the
CG9172 gene by retroposition.
Other Comments External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- A database of annotated Dmel nuclear genes encoding mitochondrial proteins
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 4 )Reported As Symbol Synonym CG9172
(
Dai et al., 2006 ,
Porcelli et al., 2007 ,
Tripoli et al., 2005 ,
Gallach et al., 2010 ,
Keleman et al., 2009.8.5 ,
Copeland et al., 2009 ,
Kim et al., 2010 ,
Metta and Schlötterer, 2010 ,
Cammarato et al., 2011 ,
Japanese National Institute of Genetics, 2012.5.21 )
Name Synonym NADH:ubiquinone oxidoreductase 20 kDa subunit
NADH ubiquinone oxidoreductase 20 kDa
Secondary FlyBase
IDs References ( 25 )Generate a list of List References by type
Recent research papers (0)
All research papers listed in FlyBase were published before 2011