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Gene Dmel\eIF5

General Information
Symbol	Dmel\eIF5	Species	D. melanogaster
Name	eIF5	Annotation symbol	CG9177
Feature type	protein_coding_gene	FlyBase ID	FBgn0030719
Gene Model Status	Current	Stock availability	5 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	14A5-14A5	Sequence location	X:15,881,041..15,886,007 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents Beta	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	The gene eIF5 is referred to in FlyBase by the symbol Dmel\eIF5 (CG9177, FBgn0030719). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: translation initiation factor activity. There is experimental evidence that it is involved in the biological process: neurogenesis. 6 alleles are reported. No phenotypic data is available. It has 7 annotated transcripts and 7 annotated polypeptides. Protein features are: Armadillo-type fold; MIF4-like, type 1/2/3; Translation initiation factor IF2/IF5; Translation initiation factor IF2/IF5, N-terminal; W2 domain. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 and 12-18 hour embryonic stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval hindgut, adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult midgut, adult hindgut, larval Malpighian tubules, larval fat body, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1630911_s_at completely aligns to an exonic region common to each of the 7 FlyBase-annotated transcript isoforms of eIF5. Gene sequence location is X:15881041..15886007.
User Contributed Data
	Beta version, feedback welcome
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2013_03
FB2013_02
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 14A5-14A5   Limits computationally determined from genome sequence between P{EP}Gβ13FEP1071 and P{EP}EP1458&P{EP}EP1522
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\eIF5 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
	Gene model reviewed during 5.50 Annotated transcripts do not represent all possible combinations of alternative exons and/or alternative promoters. Annotated transcripts do not represent all supported alternative splices within 5' UTR. Low-frequency RNA-Seq exon junction(s) not annotated.
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) eIF5-RA FBtr0074144  NM_167477   2517   464 eIF5-RB FBtr0074145  NM_132870   2588   464 eIF5-RC FBtr0074146  NM_206758   2659   464 eIF5-RD FBtr0074147  NM_206757   2587   464 eIF5-RE FBtr0074148  NM_206756   2358   464 eIF5-RF FBtr0074149  NM_206755   2383   464 eIF5-RG FBtr0074150  NM_206754   2521   464
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein eIF5-PA   FBpp0073947   51.7   464   4.89     NP_727922   AAF48553 eIF5-PB   FBpp0073948   51.7   464   4.89     NP_573098   AAF48554 eIF5-PC   FBpp0089136   51.7   464   4.89     NP_996481   AAS65378 eIF5-PD   FBpp0089137   51.7   464   4.89     NP_996480   AAS65379 eIF5-PE   FBpp0089138   51.7   464   4.89     NP_996479   AAS65380 eIF5-PF   FBpp0089139   51.7   464   4.89     NP_996478   AAS65381 eIF5-PG   FBpp0089140   51.7   464   4.89     NP_996477   AAS65382
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Translation initiation factor IF2/IF5 (IPR002735) W2 domain (IPR003307) Armadillo-type fold (IPR016024) Translation initiation factor IF2/IF5, N-terminal (IPR016189) MIF4-like, type 1/2/3 (IPR016021)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA263974   AA433284   AA439285   AA439666   AA695105   AA735558   AE014298 AAF48553   AE014298 AAF48554   AE014298 AAS65378   AE014298 AAS65379   AE014298 AAS65380   AE014298 AAS65381   AE014298 AAS65382   AI297364   AI297425   AI403435   AI531481   AW941924   AY060843 AAL28391   AY232195   BE978402   BG633235   BI167890   BI168871   BI170722   BI171531   BI172475   BI215399   BI216045   BI228154   BI229259   BI231218   BI231309   BI232928   BI236274   BI236302   BI242913   BI243116   BI355544   BI375245   BI482138   BI483983   BI485014   BI567702   BI576763   BI578084   BI579338   BI579654   BI588480   BI588964   BI610457   BI611577   BP542413   BP544561   BP559331   BP559332   CA807711   CK133254   CO154831   CO181799   CO186118   CO193173   CO264671   CO266642   CO278646   CO280471   CO285539   CO290011   CO290356   CO300320   CO300816   CO306544   CO309194   CO320741   CO322422   CO325460   CO325771   CO326475   CO328013   CO330050   CO336020   CO339849   EC057255   EC057293   EC058454   EC061612   EC063580   EC064433   EC066923   EC067723   EC068413   EC070309   EC074512   EC077150   EC077792   EC084076   EC085419   EC088545   EC091180   EC198530   EC200152   EC204450   EC207811   EC207861   EC211274   EC212312   EC213424   EC215671   EC217559   EC221559   EC223924   EC224000   EC239425   EC250599   EC255610   EC256591   EC259165   EC263201   EV577245   EV580294   EV581527   EV582123   EV582961   EV583174   EV584362   EV584486   GH945030   GH952431   GH962877   GH963224   GH963661   GH970362   GH970908   GH974541   GH976317   GH977658   GH981490   GH984994
UniProtKB/Swiss-Prot	Q9VXK6
UniProtKB/TrEMBL
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
in situ Stage Tissue/Position (including subcellular localization) Reference embryonic stage 1 -- 3   organism   (Fisher et al., 2012) Comment:maternally deposited embryonic stage 1 -- 4   pole plasm | posterior   (Lecuyer et al., 2007) embryonic stage 4 -- 6   organism | ubiquitous   (Fisher et al., 2012) embryonic stage 5   pole cell   (Lecuyer et al., 2007) embryonic stage 7 -- 8   organism | ubiquitous   (Fisher et al., 2012) pole cell   (Fisher et al., 2012) embryonic stage 9 -- 10   germline cell   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) embryonic stage 11 -- 12   anterior midgut primordium   (Fisher et al., 2012) central brain primordium   (Fisher et al., 2012) germline cell   (Fisher et al., 2012) head mesoderm   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) posterior midgut primordium   (Fisher et al., 2012) trunk mesoderm   (Fisher et al., 2012) ventral nerve cord primordium   (Fisher et al., 2012) embryonic stage 13 -- 16   dorsal pharyngeal muscle   (Fisher et al., 2012) embryonic brain   (Fisher et al., 2012) embryonic/larval midgut   (Fisher et al., 2012) embryonic/larval muscle system   (Fisher et al., 2012) organism | ubiquitous   (Fisher et al., 2012) ventral nerve cord   (Fisher et al., 2012)
Additional Descriptive Data
	eIF5 expression at embryonic stages 1-4 is localized to the posterior pole of the embryo. (Lecuyer et al., 2007)
Marker for
Subcellular Localization
CV Term
Polypeptide Expression
Additional Descriptive Data
Marker for
Subcellular Localization (GO Cellular Component)
CV term Evidence References
Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference	See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes.
FlyAtlas Anatomy Microarray
FlyAtlas Anatomical Expression Data (FlyAtlas-RNA.adult) (FlyAtlas-RNA.larva)    Styles Linear Logarithmic Heatmap Back-to-back    Scales gene max expression Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, adult crop, larval hindgut, adult Malpighian tubules, adult heart, adult fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male reproductive system, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: larval/adult midgut, adult hindgut, larval Malpighian tubules, larval fat body, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (>999.999) Linear, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    936.5 Larval Midgut    481.7 Larval Hindgut    654.3 Larval Malpighian Tubules    474.7 Larval Fat Body    339.9 Larval Salivary Gland    1168.2 Larval Trachea    799.35 Larval Carcass    731.475 Adult Head    517.4 Adult Eye    581.2 Adult Brain    950.4 Adult Thoracic-Abdominal Ganglion    944.2 Adult Crop    656.2 Adult Midgut    399.6 Adult Hindgut    493.1 Adult Malpighian Tubules    895.4 Adult Fat Body    653.9 Adult Salivary Gland    917.5 Adult Heart    643.75 Adult VirginFemale Spermatheca    1056.4 Adult InseminatedFemale Spermatheca    1069.4 Adult Ovary    851.7 Adult Testis    600.1 Adult Male Accessory Gland    685.7 Adult Carcass    435.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (936.5) Larval Midgut    481.7 Larval Hindgut  (654.3) Larval Malpighian Tubules    474.7 Larval Fat Body    339.9 Larval Salivary Gland  (1168.2) Larval Trachea  (799.35) Larval Carcass  (731.475) Adult Head  517.4 Adult Eye  (581.2) Adult Brain  (950.4) Adult Thoracic-Abdominal Ganglion  (944.2) Adult Crop  (656.2) Adult Midgut    399.6 Adult Hindgut    493.1 Adult Malpighian Tubules  (895.4) Adult Fat Body  (653.9) Adult Salivary Gland  (917.5) Adult Heart  (643.75) Adult VirginFemale Spermatheca  (1056.4) Adult InseminatedFemale Spermatheca  (1069.4) Adult Ovary  (851.7) Adult Testis  (600.1) Adult Male Accessory Gland  (685.7) Adult Carcass    435.7 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    936.5 Larval Midgut    481.7 Larval Hindgut    654.3 Larval Malpighian Tubules    474.7 Larval Fat Body    339.9 Larval Salivary Gland  (1168.2) Larval Trachea    799.35 Larval Carcass    731.475 Adult Head    517.4 Adult Eye    581.2 Adult Brain    950.4 Adult Thoracic-Abdominal Ganglion    944.2 Adult Crop    656.2 Adult Midgut    399.6 Adult Hindgut    493.1 Adult Malpighian Tubules    895.4 Adult Fat Body    653.9 Adult Salivary Gland    917.5 Adult Heart    643.75 Adult VirginFemale Spermatheca  1056.4 Adult InseminatedFemale Spermatheca  1069.4 Adult Ovary    851.7 Adult Testis    600.1 Adult Male Accessory Gland    685.7 Adult Carcass    435.7 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    936.5 Larval Midgut    481.7 Larval Hindgut    654.3 Larval Malpighian Tubules    474.7 Larval Fat Body    339.9 Larval Salivary Gland    1168.2 Larval Trachea    799.35 Larval Carcass    731.475 Adult Head    517.4 Adult Eye    581.2 Adult Brain    950.4 Adult Thoracic-Abdominal Ganglion    944.2 Adult Crop    656.2 Adult Midgut    399.6 Adult Hindgut    493.1 Adult Malpighian Tubules    895.4 Adult Fat Body    653.9 Adult Salivary Gland    917.5 Adult Heart    643.75 Adult VirginFemale Spermatheca    1056.4 Adult InseminatedFemale Spermatheca    1069.4 Adult Ovary    851.7 Adult Testis    600.1 Adult Male Accessory Gland    685.7 Adult Carcass    435.7 Expression Level Scale  Very high  log, scaled to maximum expression level Tissue   Expression Level Larval Central Nervous System    936.5 Larval Midgut    481.7 Larval Hindgut    654.3 Larval Malpighian Tubules    474.7 Larval Fat Body    339.9 Larval Salivary Gland    1168.2 Larval Trachea    799.35 Larval Carcass    731.475 Adult Head    517.4 Adult Eye    581.2 Adult Brain    950.4 Adult Thoracic-Abdominal Ganglion    944.2 Adult Crop    656.2 Adult Midgut    399.6 Adult Hindgut    493.1 Adult Malpighian Tubules    895.4 Adult Fat Body    653.9 Adult Salivary Gland    917.5 Adult Heart    643.75 Adult VirginFemale Spermatheca    1056.4 Adult InseminatedFemale Spermatheca    1069.4 Adult Ovary    851.7 Adult Testis    600.1 Adult Male Accessory Gland    685.7 Adult Carcass    435.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  (936.5) Larval Midgut    481.7 Larval Hindgut  654.3 Larval Malpighian Tubules    474.7 Larval Fat Body    339.9 Larval Salivary Gland  (1168.2) Larval Trachea  799.35 Larval Carcass  731.475 Adult Head  517.4 Adult Eye  581.2 Adult Brain  (950.4) Adult Thoracic-Abdominal Ganglion  (944.2) Adult Crop  656.2 Adult Midgut    399.6 Adult Hindgut    493.1 Adult Malpighian Tubules  (895.4) Adult Fat Body  653.9 Adult Salivary Gland  (917.5) Adult Heart  643.75 Adult VirginFemale Spermatheca  (1056.4) Adult InseminatedFemale Spermatheca  (1069.4) Adult Ovary  (851.7) Adult Testis  600.1 Adult Male Accessory Gland  685.7 Adult Carcass    435.7 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    936.5 Larval Midgut    481.7 Larval Hindgut    654.3 Larval Malpighian Tubules    474.7 Larval Fat Body    339.9 Larval Salivary Gland  1168.2 Larval Trachea    799.35 Larval Carcass    731.475 Adult Head    517.4 Adult Eye    581.2 Adult Brain    950.4 Adult Thoracic-Abdominal Ganglion    944.2 Adult Crop    656.2 Adult Midgut    399.6 Adult Hindgut    493.1 Adult Malpighian Tubules    895.4 Adult Fat Body    653.9 Adult Salivary Gland    917.5 Adult Heart    643.75 Adult VirginFemale Spermatheca  1056.4 Adult InseminatedFemale Spermatheca  1069.4 Adult Ovary    851.7 Adult Testis    600.1 Adult Male Accessory Gland    685.7 Adult Carcass    435.7 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    936.5 Larval Midgut    481.7 Larval Hindgut    654.3 Larval Malpighian Tubules    474.7 Larval Fat Body    339.9 Larval Salivary Gland    1168.2 Larval Trachea    799.35 Larval Carcass    731.475 Adult Head    517.4 Adult Eye    581.2 Adult Brain    950.4 Adult Thoracic-Abdominal Ganglion    944.2 Adult Crop    656.2 Adult Midgut    399.6 Adult Hindgut    493.1 Adult Malpighian Tubules    895.4 Adult Fat Body    653.9 Adult Salivary Gland    917.5 Adult Heart    643.75 Adult VirginFemale Spermatheca    1056.4 Adult InseminatedFemale Spermatheca    1069.4 Adult Ovary    851.7 Adult Testis    600.1 Adult Male Accessory Gland    685.7 Adult Carcass    435.7 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    517.4   NA  Eye    581.2   NA  Brain    950.4   936.5  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    944.2   NA  Crop    656.2   481.7  Midgut    399.6   654.3  Hindgut    493.1   474.7  Malpighian Tubules    895.4   339.9  Fat Body    653.9   1168.2  Salivary Gland    917.5   NA  Heart    643.75   799.35  Trachea    NA   NA  VirginFemale Spermatheca    1056.4   NA  InseminatedFemale Spermatheca    1069.4   NA  Ovary    851.7   NA  Testis    600.1   NA  Male Accessory Gland    685.7   731.475  Carcass    435.7 FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
modENCODE Anatomy RNA-Seq
modENCODE Tissue Expression Data (modENCODE_mRNA-Seq_tissues)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    149 central nervous system, larvae L3    226 central nervous system, pupae P8    268 head, virgin 1-day female    182 head, virgin 4-day female    150 head, virgin 20-day female    74 head, mated 1-day female    146 head, mated 4-day female    131 head, mated 20-day female    74 head, mated 1-day male    198 head, mated 4-day male    183 head, mated 20-day male    162 salivary gland, larvae L3 wandering    63 salivary gland, white prepupae    172 digestive system, larvae L3 wandering    109 digestive system, 1-day adult    76 digestive system, 4-day adult    109 digestive system, 20-day adult    68 fat body, larvae L3 wandering    52 fat body, white prepupae    75 fat body, pupae P8    160 carcass, larvae L3 wandering    142 carcass, 1-day adult    105 carcass, 4-day adult    134 carcass, 20-day adult    89 ovary, virgin 4-day female    288 ovary, mated 4-day female    309 testis, mated 4-day male    77 accessory gland, mated 4-day male    61 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (149) central nervous system, larvae L3  (226) central nervous system, pupae P8  (268) head, virgin 1-day female  (182) head, virgin 4-day female  (150) head, virgin 20-day female  (74) head, mated 1-day female  (146) head, mated 4-day female  (131) head, mated 20-day female  (74) head, mated 1-day male  (198) head, mated 4-day male  (183) head, mated 20-day male  (162) salivary gland, larvae L3 wandering  (63) salivary gland, white prepupae  (172) digestive system, larvae L3 wandering  (109) digestive system, 1-day adult  (76) digestive system, 4-day adult  (109) digestive system, 20-day adult  (68) fat body, larvae L3 wandering  (52) fat body, white prepupae  (75) fat body, pupae P8  (160) carcass, larvae L3 wandering  (142) carcass, 1-day adult  (105) carcass, 4-day adult  (134) carcass, 20-day adult  (89) ovary, virgin 4-day female  (288) ovary, mated 4-day female  (309) testis, mated 4-day male  (77) accessory gland, mated 4-day male  (61) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (149) central nervous system, larvae L3  (226) central nervous system, pupae P8  (268) head, virgin 1-day female  (182) head, virgin 4-day female  (150) head, virgin 20-day female    74 head, mated 1-day female  (146) head, mated 4-day female  (131) head, mated 20-day female    74 head, mated 1-day male  (198) head, mated 4-day male  (183) head, mated 20-day male  (162) salivary gland, larvae L3 wandering    63 salivary gland, white prepupae  (172) digestive system, larvae L3 wandering  (109) digestive system, 1-day adult    76 digestive system, 4-day adult  (109) digestive system, 20-day adult    68 fat body, larvae L3 wandering    52 fat body, white prepupae    75 fat body, pupae P8  (160) carcass, larvae L3 wandering  (142) carcass, 1-day adult  105 carcass, 4-day adult  (134) carcass, 20-day adult    89 ovary, virgin 4-day female  (288) ovary, mated 4-day female  (309) testis, mated 4-day male    77 accessory gland, mated 4-day male    61 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    149 central nervous system, larvae L3    226 central nervous system, pupae P8    268 head, virgin 1-day female    182 head, virgin 4-day female    150 head, virgin 20-day female    74 head, mated 1-day female    146 head, mated 4-day female    131 head, mated 20-day female    74 head, mated 1-day male    198 head, mated 4-day male    183 head, mated 20-day male    162 salivary gland, larvae L3 wandering    63 salivary gland, white prepupae    172 digestive system, larvae L3 wandering    109 digestive system, 1-day adult    76 digestive system, 4-day adult    109 digestive system, 20-day adult    68 fat body, larvae L3 wandering    52 fat body, white prepupae    75 fat body, pupae P8    160 carcass, larvae L3 wandering    142 carcass, 1-day adult    105 carcass, 4-day adult    134 carcass, 20-day adult    89 ovary, virgin 4-day female    288 ovary, mated 4-day female    309 testis, mated 4-day male    77 accessory gland, mated 4-day male    61 Expression Level Scale  Extremely high  log, scaled to maximum expression level Tissue   Expression Level imaginal disc, larvae L3 wandering    149 central nervous system, larvae L3    226 central nervous system, pupae P8    268 head, virgin 1-day female    182 head, virgin 4-day female    150 head, virgin 20-day female    74 head, mated 1-day female    146 head, mated 4-day female    131 head, mated 20-day female    74 head, mated 1-day male    198 head, mated 4-day male    183 head, mated 20-day male    162 salivary gland, larvae L3 wandering    63 salivary gland, white prepupae    172 digestive system, larvae L3 wandering    109 digestive system, 1-day adult    76 digestive system, 4-day adult    109 digestive system, 20-day adult    68 fat body, larvae L3 wandering    52 fat body, white prepupae    75 fat body, pupae P8    160 carcass, larvae L3 wandering    142 carcass, 1-day adult    105 carcass, 4-day adult    134 carcass, 20-day adult    89 ovary, virgin 4-day female    288 ovary, mated 4-day female    309 testis, mated 4-day male    77 accessory gland, mated 4-day male    61 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (149) central nervous system, larvae L3  (226) central nervous system, pupae P8  (268) head, virgin 1-day female  (182) head, virgin 4-day female  (150) head, virgin 20-day female  (74) head, mated 1-day female  (146) head, mated 4-day female  (131) head, mated 20-day female  (74) head, mated 1-day male  (198) head, mated 4-day male  (183) head, mated 20-day male  (162) salivary gland, larvae L3 wandering  (63) salivary gland, white prepupae  (172) digestive system, larvae L3 wandering  (109) digestive system, 1-day adult  (76) digestive system, 4-day adult  (109) digestive system, 20-day adult  (68) fat body, larvae L3 wandering  (52) fat body, white prepupae  (75) fat body, pupae P8  (160) carcass, larvae L3 wandering  (142) carcass, 1-day adult  (105) carcass, 4-day adult  (134) carcass, 20-day adult  (89) ovary, virgin 4-day female  (288) ovary, mated 4-day female  (309) testis, mated 4-day male  (77) accessory gland, mated 4-day male  (61) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Tissue   Expression Level imaginal disc, larvae L3 wandering  (149) central nervous system, larvae L3  (226) central nervous system, pupae P8  (268) head, virgin 1-day female  (182) head, virgin 4-day female  (150) head, virgin 20-day female    74 head, mated 1-day female  (146) head, mated 4-day female  131 head, mated 20-day female    74 head, mated 1-day male  (198) head, mated 4-day male  (183) head, mated 20-day male  (162) salivary gland, larvae L3 wandering    63 salivary gland, white prepupae  (172) digestive system, larvae L3 wandering  109 digestive system, 1-day adult    76 digestive system, 4-day adult  109 digestive system, 20-day adult    68 fat body, larvae L3 wandering    52 fat body, white prepupae    75 fat body, pupae P8  (160) carcass, larvae L3 wandering  142 carcass, 1-day adult  105 carcass, 4-day adult  134 carcass, 20-day adult    89 ovary, virgin 4-day female  (288) ovary, mated 4-day female  (309) testis, mated 4-day male    77 accessory gland, mated 4-day male    61 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Tissue   Expression Level imaginal disc, larvae L3 wandering    149 central nervous system, larvae L3    226 central nervous system, pupae P8    268 head, virgin 1-day female    182 head, virgin 4-day female    150 head, virgin 20-day female    74 head, mated 1-day female    146 head, mated 4-day female    131 head, mated 20-day female    74 head, mated 1-day male    198 head, mated 4-day male    183 head, mated 20-day male    162 salivary gland, larvae L3 wandering    63 salivary gland, white prepupae    172 digestive system, larvae L3 wandering    109 digestive system, 1-day adult    76 digestive system, 4-day adult    109 digestive system, 20-day adult    68 fat body, larvae L3 wandering    52 fat body, white prepupae    75 fat body, pupae P8    160 carcass, larvae L3 wandering    142 carcass, 1-day adult    105 carcass, 4-day adult    134 carcass, 20-day adult    89 ovary, virgin 4-day female    288 ovary, mated 4-day female    309 testis, mated 4-day male    77 accessory gland, mated 4-day male    61 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Tissue   Expression Level imaginal disc, larvae L3 wandering     central nervous system, larvae L3     central nervous system, pupae P8     head, virgin 1-day female     head, virgin 4-day female     head, virgin 20-day female     head, mated 1-day female     head, mated 4-day female     head, mated 20-day female     head, mated 1-day male     head, mated 4-day male     head, mated 20-day male     salivary gland, larvae L3 wandering     salivary gland, white prepupae     digestive system, larvae L3 wandering     digestive system, 1-day adult     digestive system, 4-day adult     digestive system, 20-day adult     fat body, larvae L3 wandering     fat body, white prepupae     fat body, pupae P8     carcass, larvae L3 wandering     carcass, 1-day adult     carcass, 4-day adult     carcass, 20-day adult     ovary, virgin 4-day female     ovary, mated 4-day female     testis, mated 4-day male     accessory gland, mated 4-day male
modENCODE Development RNA-Seq
modENCODE Temporal Expression Data (modENCODE_mRNA-Seq_U)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of very high expression to a trough of moderately high expression. Peak expression observed within 00-06 and 12-18 hour embryonic stages. [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    108 embryo 02-04hr    165 embryo 04-06hr    130 embryo 06-08hr    93 embryo 08-10hr    114 embryo 10-12hr    97 embryo 12-14hr    140 embryo 14-16hr    89 embryo 16-18hr    102 embryo 18-20hr    67 embryo 20-22hr    82 embryo 22-24hr    102 larva L1    69 larva L2    65 larva L3 12hr old    49 larva L3 puffstage 1-2    46 larva L3 puffstage 3-6    55 larva L3 puffstage 7-9    79 white prepupae new    78 white prepupae 12hr    74 white prepupae 24hr    82 pupae 2d postWPP    90 pupae 3d postWPP    74 pupae 4d postWPP    46 adult male 01day    60 adult male 05day    53 adult male 30day    47 adult female 01day    60 adult female 05day    102 adult female 30day    91 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (108) embryo 02-04hr  (165) embryo 04-06hr  (130) embryo 06-08hr  (93) embryo 08-10hr  (114) embryo 10-12hr  (97) embryo 12-14hr  (140) embryo 14-16hr  (89) embryo 16-18hr  (102) embryo 18-20hr  (67) embryo 20-22hr  (82) embryo 22-24hr  (102) larva L1  (69) larva L2  (65) larva L3 12hr old  (49) larva L3 puffstage 1-2  (46) larva L3 puffstage 3-6  (55) larva L3 puffstage 7-9  (79) white prepupae new  (78) white prepupae 12hr  (74) white prepupae 24hr  (82) pupae 2d postWPP  (90) pupae 3d postWPP  (74) pupae 4d postWPP  (46) adult male 01day  (60) adult male 05day  (53) adult male 30day  (47) adult female 01day  (60) adult female 05day  (102) adult female 30day  (91) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  (108) embryo 02-04hr  (165) embryo 04-06hr  (130) embryo 06-08hr    93 embryo 08-10hr  (114) embryo 10-12hr    97 embryo 12-14hr  (140) embryo 14-16hr    89 embryo 16-18hr  102 embryo 18-20hr    67 embryo 20-22hr    82 embryo 22-24hr  102 larva L1    69 larva L2    65 larva L3 12hr old    49 larva L3 puffstage 1-2    46 larva L3 puffstage 3-6    55 larva L3 puffstage 7-9    79 white prepupae new    78 white prepupae 12hr    74 white prepupae 24hr    82 pupae 2d postWPP    90 pupae 3d postWPP    74 pupae 4d postWPP    46 adult male 01day    60 adult male 05day    53 adult male 30day    47 adult female 01day    60 adult female 05day  102 adult female 30day    91 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    108 embryo 02-04hr    165 embryo 04-06hr    130 embryo 06-08hr    93 embryo 08-10hr    114 embryo 10-12hr    97 embryo 12-14hr    140 embryo 14-16hr    89 embryo 16-18hr    102 embryo 18-20hr    67 embryo 20-22hr    82 embryo 22-24hr    102 larva L1    69 larva L2    65 larva L3 12hr old    49 larva L3 puffstage 1-2    46 larva L3 puffstage 3-6    55 larva L3 puffstage 7-9    79 white prepupae new    78 white prepupae 12hr    74 white prepupae 24hr    82 pupae 2d postWPP    90 pupae 3d postWPP    74 pupae 4d postWPP    46 adult male 01day    60 adult male 05day    53 adult male 30day    47 adult female 01day    60 adult female 05day    102 adult female 30day    91 Expression Level Scale  Extremely high  log, scaled to maximum expression level Developmental Stage   Expression Level embryo 00-02hr    108 embryo 02-04hr    165 embryo 04-06hr    130 embryo 06-08hr    93 embryo 08-10hr    114 embryo 10-12hr    97 embryo 12-14hr    140 embryo 14-16hr    89 embryo 16-18hr    102 embryo 18-20hr    67 embryo 20-22hr    82 embryo 22-24hr    102 larva L1    69 larva L2    65 larva L3 12hr old    49 larva L3 puffstage 1-2    46 larva L3 puffstage 3-6    55 larva L3 puffstage 7-9    79 white prepupae new    78 white prepupae 12hr    74 white prepupae 24hr    82 pupae 2d postWPP    90 pupae 3d postWPP    74 pupae 4d postWPP    46 adult male 01day    60 adult male 05day    53 adult male 30day    47 adult female 01day    60 adult female 05day    102 adult female 30day    91 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (108) embryo 02-04hr  (165) embryo 04-06hr  (130) embryo 06-08hr  (93) embryo 08-10hr  (114) embryo 10-12hr  (97) embryo 12-14hr  (140) embryo 14-16hr  (89) embryo 16-18hr  (102) embryo 18-20hr  (67) embryo 20-22hr  (82) embryo 22-24hr  (102) larva L1  (69) larva L2  (65) larva L3 12hr old  (49) larva L3 puffstage 1-2  (46) larva L3 puffstage 3-6  (55) larva L3 puffstage 7-9  (79) white prepupae new  (78) white prepupae 12hr  (74) white prepupae 24hr  (82) pupae 2d postWPP  (90) pupae 3d postWPP  (74) pupae 4d postWPP  (46) adult male 01day  (60) adult male 05day  (53) adult male 30day  (47) adult female 01day  (60) adult female 05day  (102) adult female 30day  (91) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr  108 embryo 02-04hr  (165) embryo 04-06hr  130 embryo 06-08hr    93 embryo 08-10hr  114 embryo 10-12hr    97 embryo 12-14hr  140 embryo 14-16hr    89 embryo 16-18hr  102 embryo 18-20hr    67 embryo 20-22hr    82 embryo 22-24hr  102 larva L1    69 larva L2    65 larva L3 12hr old    49 larva L3 puffstage 1-2    46 larva L3 puffstage 3-6    55 larva L3 puffstage 7-9    79 white prepupae new    78 white prepupae 12hr    74 white prepupae 24hr    82 pupae 2d postWPP    90 pupae 3d postWPP    74 pupae 4d postWPP    46 adult male 01day    60 adult male 05day    53 adult male 30day    47 adult female 01day    60 adult female 05day  102 adult female 30day    91 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    108 embryo 02-04hr    165 embryo 04-06hr    130 embryo 06-08hr    93 embryo 08-10hr    114 embryo 10-12hr    97 embryo 12-14hr    140 embryo 14-16hr    89 embryo 16-18hr    102 embryo 18-20hr    67 embryo 20-22hr    82 embryo 22-24hr    102 larva L1    69 larva L2    65 larva L3 12hr old    49 larva L3 puffstage 1-2    46 larva L3 puffstage 3-6    55 larva L3 puffstage 7-9    79 white prepupae new    78 white prepupae 12hr    74 white prepupae 24hr    82 pupae 2d postWPP    90 pupae 3d postWPP    74 pupae 4d postWPP    46 adult male 01day    60 adult male 05day    53 adult male 30day    47 adult female 01day    60 adult female 05day    102 adult female 30day    91 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     modENCODE Temporal Expression Data (Graveley et al., 2011)
modENCODE Cell Lines RNA-Seq
modENCODE Cell Line Expression Data (modENCODE_mRNA-Seq_cell.A) (modENCODE_mRNA-Seq_cell.B)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    164 Schneider line 2 Sg4    104 embryonic 1182-4H    161 embryonic GM2    209 embryonic Kc167    129 embryonic S1    269 embryonic S3    258 leg disc CME L1    148 wing disc CME-W2    127 wing disc ML-DmD8    140 wing disc ML-DmD9    104 wing disc ML-DmD16-c3    138 wing disc ML-DmD21    73 wing disc ML-DmD32    76 haltere disc ML-DmD17-c3    111 eye-antennal disc ML-DmD11    98 antennal disc ML-DmD20-c5    70 mixed discs ML-DmD4-c1    115 CNS ML-DmBG1-c1    155 CNS ML-DmBG2-c2    114 tumorous blood cells mbn2    185 ovary fGS/OSS    131 ovary OSC    169 ovary OSS    154 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (164) Schneider line 2 Sg4  (104) embryonic 1182-4H  (161) embryonic GM2  (209) embryonic Kc167  (129) embryonic S1  (269) embryonic S3  (258) leg disc CME L1  (148) wing disc CME-W2  (127) wing disc ML-DmD8  (140) wing disc ML-DmD9  (104) wing disc ML-DmD16-c3  (138) wing disc ML-DmD21  (73) wing disc ML-DmD32  (76) haltere disc ML-DmD17-c3  (111) eye-antennal disc ML-DmD11  (98) antennal disc ML-DmD20-c5  (70) mixed discs ML-DmD4-c1  (115) CNS ML-DmBG1-c1  (155) CNS ML-DmBG2-c2  (114) tumorous blood cells mbn2  (185) ovary fGS/OSS  (131) ovary OSC  (169) ovary OSS  (154) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (164) Schneider line 2 Sg4  104 embryonic 1182-4H  (161) embryonic GM2  (209) embryonic Kc167  (129) embryonic S1  (269) embryonic S3  (258) leg disc CME L1  (148) wing disc CME-W2  (127) wing disc ML-DmD8  (140) wing disc ML-DmD9  104 wing disc ML-DmD16-c3  (138) wing disc ML-DmD21    73 wing disc ML-DmD32    76 haltere disc ML-DmD17-c3  (111) eye-antennal disc ML-DmD11    98 antennal disc ML-DmD20-c5    70 mixed discs ML-DmD4-c1  (115) CNS ML-DmBG1-c1  (155) CNS ML-DmBG2-c2  (114) tumorous blood cells mbn2  (185) ovary fGS/OSS  (131) ovary OSC  (169) ovary OSS  (154) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    164 Schneider line 2 Sg4    104 embryonic 1182-4H    161 embryonic GM2    209 embryonic Kc167    129 embryonic S1    269 embryonic S3    258 leg disc CME L1    148 wing disc CME-W2    127 wing disc ML-DmD8    140 wing disc ML-DmD9    104 wing disc ML-DmD16-c3    138 wing disc ML-DmD21    73 wing disc ML-DmD32    76 haltere disc ML-DmD17-c3    111 eye-antennal disc ML-DmD11    98 antennal disc ML-DmD20-c5    70 mixed discs ML-DmD4-c1    115 CNS ML-DmBG1-c1    155 CNS ML-DmBG2-c2    114 tumorous blood cells mbn2    185 ovary fGS/OSS    131 ovary OSC    169 ovary OSS    154 Expression Level Scale  Extremely high  log, scaled to maximum expression level Cell Line   Expression Level Schneider line 2 S2R+    164 Schneider line 2 Sg4    104 embryonic 1182-4H    161 embryonic GM2    209 embryonic Kc167    129 embryonic S1    269 embryonic S3    258 leg disc CME L1    148 wing disc CME-W2    127 wing disc ML-DmD8    140 wing disc ML-DmD9    104 wing disc ML-DmD16-c3    138 wing disc ML-DmD21    73 wing disc ML-DmD32    76 haltere disc ML-DmD17-c3    111 eye-antennal disc ML-DmD11    98 antennal disc ML-DmD20-c5    70 mixed discs ML-DmD4-c1    115 CNS ML-DmBG1-c1    155 CNS ML-DmBG2-c2    114 tumorous blood cells mbn2    185 ovary fGS/OSS    131 ovary OSC    169 ovary OSS    154 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Cell Line   Expression Level Schneider line 2 S2R+  (164) Schneider line 2 Sg4  (104) embryonic 1182-4H  (161) embryonic GM2  (209) embryonic Kc167  (129) embryonic S1  (269) embryonic S3  (258) leg disc CME L1  (148) wing disc CME-W2  (127) wing disc ML-DmD8  (140) wing disc ML-DmD9  (104) wing disc ML-DmD16-c3  (138) wing disc ML-DmD21  (73) wing disc ML-DmD32  (76) haltere disc ML-DmD17-c3  (111) eye-antennal disc ML-DmD11  (98) antennal disc ML-DmD20-c5  (70) mixed discs ML-DmD4-c1  (115) CNS ML-DmBG1-c1  (155) CNS ML-DmBG2-c2  (114) tumorous blood cells mbn2  (185) ovary fGS/OSS  (131) ovary OSC  (169) ovary OSS  (154) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Cell Line   Expression Level Schneider line 2 S2R+  (164) Schneider line 2 Sg4  104 embryonic 1182-4H  (161) embryonic GM2  (209) embryonic Kc167  129 embryonic S1  (269) embryonic S3  (258) leg disc CME L1  (148) wing disc CME-W2  127 wing disc ML-DmD8  140 wing disc ML-DmD9  104 wing disc ML-DmD16-c3  138 wing disc ML-DmD21    73 wing disc ML-DmD32    76 haltere disc ML-DmD17-c3  111 eye-antennal disc ML-DmD11    98 antennal disc ML-DmD20-c5    70 mixed discs ML-DmD4-c1  115 CNS ML-DmBG1-c1  (155) CNS ML-DmBG2-c2  114 tumorous blood cells mbn2  (185) ovary fGS/OSS  131 ovary OSC  (169) ovary OSS  (154) Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Cell Line   Expression Level Schneider line 2 S2R+    164 Schneider line 2 Sg4    104 embryonic 1182-4H    161 embryonic GM2    209 embryonic Kc167    129 embryonic S1    269 embryonic S3    258 leg disc CME L1    148 wing disc CME-W2    127 wing disc ML-DmD8    140 wing disc ML-DmD9    104 wing disc ML-DmD16-c3    138 wing disc ML-DmD21    73 wing disc ML-DmD32    76 haltere disc ML-DmD17-c3    111 eye-antennal disc ML-DmD11    98 antennal disc ML-DmD20-c5    70 mixed discs ML-DmD4-c1    115 CNS ML-DmBG1-c1    155 CNS ML-DmBG2-c2    114 tumorous blood cells mbn2    185 ovary fGS/OSS    131 ovary OSC    169 ovary OSS    154 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Cell Line   Expression Level Schneider line 2 S2R+     Schneider line 2 Sg4     embryonic 1182-4H     embryonic GM2     embryonic Kc167     embryonic S1     embryonic S3     leg disc CME L1     wing disc CME-W2     wing disc ML-DmD8     wing disc ML-DmD9     wing disc ML-DmD16-c3     wing disc ML-DmD21     wing disc ML-DmD32     haltere disc ML-DmD17-c3     eye-antennal disc ML-DmD11     antennal disc ML-DmD20-c5     mixed discs ML-DmD4-c1     CNS ML-DmBG1-c1     CNS ML-DmBG2-c2     tumorous blood cells mbn2     ovary fGS/OSS     ovary OSC     ovary OSS
modENCODE Treatments RNA-Seq
modENCODE Treatment Expression Data (modENCODE_mRNA-Seq_treatments)    Styles Linear Logarithmic Heatmap    Scales gene max expression Moderate expression bin max High expression bin max Extremely high expression bin max [download data (TSV)] Guide to modENCODE expression level colors   No/Extremely low expression (0 - 0)   Very low expression (1 - 3)   Low expression (4 - 10)   Moderate expression (11 - 25)   Moderately high expression (26 - 50)   High expression (51 - 100)   Very high expression (101 - 1000)   Extremely high expression (>1000) Linear, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    105 cold shock, 4-day adult    88 heat shock, 4-day adult    114 Cadmium 50 mM 6 hrs, larvae L3    67 Cadmium 50 mM 12 hrs, larvae L3    133 Cadmium 50 mM 48 hrs, 4-day adult    133 Cadmium 100 mM 48 hrs, 4-day adult    242 Copper 0.5 mM 12 hrs, larvae L3    62 Copper 15 mM 48 hrs, 4-day adult    345 Zinc 5 mM 12 hrs, larvae L3    98 Zinc 4.5 mM 48 hrs, 4-day adult    200 Ethanol 2.5% 3 hrs, larvae L3    133 Ethanol 5% 3 hrs, larvae L3    89 Ethanol 10% 3 hrs, larvae L3    86 Caffeine 1.5 mg/ml 4 hrs, larvae L3    78 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    229 Caffeine 25 mg/ml 48 hrs, 4-day adult    109 Paraquat 5 mM 48 hrs, 4-day adult    180 Paraquat 10 mM 48 hrs, 4-day adult    110 Rotenone 2 μg 12 hrs, larvae L3    122 Rotenone 8 μg 12 hrs, larvae L3    71 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (105) cold shock, 4-day adult  (88) heat shock, 4-day adult  (114) Cadmium 50 mM 6 hrs, larvae L3  (67) Cadmium 50 mM 12 hrs, larvae L3  (133) Cadmium 50 mM 48 hrs, 4-day adult  (133) Cadmium 100 mM 48 hrs, 4-day adult  (242) Copper 0.5 mM 12 hrs, larvae L3  (62) Copper 15 mM 48 hrs, 4-day adult  (345) Zinc 5 mM 12 hrs, larvae L3  (98) Zinc 4.5 mM 48 hrs, 4-day adult  (200) Ethanol 2.5% 3 hrs, larvae L3  (133) Ethanol 5% 3 hrs, larvae L3  (89) Ethanol 10% 3 hrs, larvae L3  (86) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (78) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (229) Caffeine 25 mg/ml 48 hrs, 4-day adult  (109) Paraquat 5 mM 48 hrs, 4-day adult  (180) Paraquat 10 mM 48 hrs, 4-day adult  (110) Rotenone 2 μg 12 hrs, larvae L3  (122) Rotenone 8 μg 12 hrs, larvae L3  (71) Expression Level Scale  Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  105 cold shock, 4-day adult    88 heat shock, 4-day adult  (114) Cadmium 50 mM 6 hrs, larvae L3    67 Cadmium 50 mM 12 hrs, larvae L3  (133) Cadmium 50 mM 48 hrs, 4-day adult  (133) Cadmium 100 mM 48 hrs, 4-day adult  (242) Copper 0.5 mM 12 hrs, larvae L3    62 Copper 15 mM 48 hrs, 4-day adult  (345) Zinc 5 mM 12 hrs, larvae L3    98 Zinc 4.5 mM 48 hrs, 4-day adult  (200) Ethanol 2.5% 3 hrs, larvae L3  (133) Ethanol 5% 3 hrs, larvae L3    89 Ethanol 10% 3 hrs, larvae L3    86 Caffeine 1.5 mg/ml 4 hrs, larvae L3    78 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (229) Caffeine 25 mg/ml 48 hrs, 4-day adult  (109) Paraquat 5 mM 48 hrs, 4-day adult  (180) Paraquat 10 mM 48 hrs, 4-day adult  (110) Rotenone 2 μg 12 hrs, larvae L3  (122) Rotenone 8 μg 12 hrs, larvae L3    71 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    105 cold shock, 4-day adult    88 heat shock, 4-day adult    114 Cadmium 50 mM 6 hrs, larvae L3    67 Cadmium 50 mM 12 hrs, larvae L3    133 Cadmium 50 mM 48 hrs, 4-day adult    133 Cadmium 100 mM 48 hrs, 4-day adult    242 Copper 0.5 mM 12 hrs, larvae L3    62 Copper 15 mM 48 hrs, 4-day adult    345 Zinc 5 mM 12 hrs, larvae L3    98 Zinc 4.5 mM 48 hrs, 4-day adult    200 Ethanol 2.5% 3 hrs, larvae L3    133 Ethanol 5% 3 hrs, larvae L3    89 Ethanol 10% 3 hrs, larvae L3    86 Caffeine 1.5 mg/ml 4 hrs, larvae L3    78 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    229 Caffeine 25 mg/ml 48 hrs, 4-day adult    109 Paraquat 5 mM 48 hrs, 4-day adult    180 Paraquat 10 mM 48 hrs, 4-day adult    110 Rotenone 2 μg 12 hrs, larvae L3    122 Rotenone 8 μg 12 hrs, larvae L3    71 Expression Level Scale  Extremely high  log, scaled to maximum expression level Treatment   Expression Level extended cold, 4-day adult    105 cold shock, 4-day adult    88 heat shock, 4-day adult    114 Cadmium 50 mM 6 hrs, larvae L3    67 Cadmium 50 mM 12 hrs, larvae L3    133 Cadmium 50 mM 48 hrs, 4-day adult    133 Cadmium 100 mM 48 hrs, 4-day adult    242 Copper 0.5 mM 12 hrs, larvae L3    62 Copper 15 mM 48 hrs, 4-day adult    345 Zinc 5 mM 12 hrs, larvae L3    98 Zinc 4.5 mM 48 hrs, 4-day adult    200 Ethanol 2.5% 3 hrs, larvae L3    133 Ethanol 5% 3 hrs, larvae L3    89 Ethanol 10% 3 hrs, larvae L3    86 Caffeine 1.5 mg/ml 4 hrs, larvae L3    78 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    229 Caffeine 25 mg/ml 48 hrs, 4-day adult    109 Paraquat 5 mM 48 hrs, 4-day adult    180 Paraquat 10 mM 48 hrs, 4-day adult    110 Rotenone 2 μg 12 hrs, larvae L3    122 Rotenone 8 μg 12 hrs, larvae L3    71 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Moderate expression Treatment   Expression Level extended cold, 4-day adult  (105) cold shock, 4-day adult  (88) heat shock, 4-day adult  (114) Cadmium 50 mM 6 hrs, larvae L3  (67) Cadmium 50 mM 12 hrs, larvae L3  (133) Cadmium 50 mM 48 hrs, 4-day adult  (133) Cadmium 100 mM 48 hrs, 4-day adult  (242) Copper 0.5 mM 12 hrs, larvae L3  (62) Copper 15 mM 48 hrs, 4-day adult  (345) Zinc 5 mM 12 hrs, larvae L3  (98) Zinc 4.5 mM 48 hrs, 4-day adult  (200) Ethanol 2.5% 3 hrs, larvae L3  (133) Ethanol 5% 3 hrs, larvae L3  (89) Ethanol 10% 3 hrs, larvae L3  (86) Caffeine 1.5 mg/ml 4 hrs, larvae L3  (78) Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (229) Caffeine 25 mg/ml 48 hrs, 4-day adult  (109) Paraquat 5 mM 48 hrs, 4-day adult  (180) Paraquat 10 mM 48 hrs, 4-day adult  (110) Rotenone 2 μg 12 hrs, larvae L3  (122) Rotenone 8 μg 12 hrs, larvae L3  (71) Expression Level Scale  Very low   Low   Moderate   Moderately high  log, scaled to High expression Treatment   Expression Level extended cold, 4-day adult  105 cold shock, 4-day adult    88 heat shock, 4-day adult  114 Cadmium 50 mM 6 hrs, larvae L3    67 Cadmium 50 mM 12 hrs, larvae L3  133 Cadmium 50 mM 48 hrs, 4-day adult  133 Cadmium 100 mM 48 hrs, 4-day adult  (242) Copper 0.5 mM 12 hrs, larvae L3    62 Copper 15 mM 48 hrs, 4-day adult  (345) Zinc 5 mM 12 hrs, larvae L3    98 Zinc 4.5 mM 48 hrs, 4-day adult  (200) Ethanol 2.5% 3 hrs, larvae L3  133 Ethanol 5% 3 hrs, larvae L3    89 Ethanol 10% 3 hrs, larvae L3    86 Caffeine 1.5 mg/ml 4 hrs, larvae L3    78 Caffeine 2.5 mg/ml 48 hrs, 4-day adult  (229) Caffeine 25 mg/ml 48 hrs, 4-day adult  109 Paraquat 5 mM 48 hrs, 4-day adult  (180) Paraquat 10 mM 48 hrs, 4-day adult  110 Rotenone 2 μg 12 hrs, larvae L3  122 Rotenone 8 μg 12 hrs, larvae L3    71 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Treatment   Expression Level extended cold, 4-day adult    105 cold shock, 4-day adult    88 heat shock, 4-day adult    114 Cadmium 50 mM 6 hrs, larvae L3    67 Cadmium 50 mM 12 hrs, larvae L3    133 Cadmium 50 mM 48 hrs, 4-day adult    133 Cadmium 100 mM 48 hrs, 4-day adult    242 Copper 0.5 mM 12 hrs, larvae L3    62 Copper 15 mM 48 hrs, 4-day adult    345 Zinc 5 mM 12 hrs, larvae L3    98 Zinc 4.5 mM 48 hrs, 4-day adult    200 Ethanol 2.5% 3 hrs, larvae L3    133 Ethanol 5% 3 hrs, larvae L3    89 Ethanol 10% 3 hrs, larvae L3    86 Caffeine 1.5 mg/ml 4 hrs, larvae L3    78 Caffeine 2.5 mg/ml 48 hrs, 4-day adult    229 Caffeine 25 mg/ml 48 hrs, 4-day adult    109 Paraquat 5 mM 48 hrs, 4-day adult    180 Paraquat 10 mM 48 hrs, 4-day adult    110 Rotenone 2 μg 12 hrs, larvae L3    122 Rotenone 8 μg 12 hrs, larvae L3    71 Expression Level Scale  Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Treatment   Expression Level extended cold, 4-day adult     cold shock, 4-day adult     heat shock, 4-day adult     Cadmium 50 mM 6 hrs, larvae L3     Cadmium 50 mM 12 hrs, larvae L3     Cadmium 50 mM 48 hrs, 4-day adult     Cadmium 100 mM 48 hrs, 4-day adult     Copper 0.5 mM 12 hrs, larvae L3     Copper 15 mM 48 hrs, 4-day adult     Zinc 5 mM 12 hrs, larvae L3     Zinc 4.5 mM 48 hrs, 4-day adult     Ethanol 2.5% 3 hrs, larvae L3     Ethanol 5% 3 hrs, larvae L3     Ethanol 10% 3 hrs, larvae L3     Caffeine 1.5 mg/ml 4 hrs, larvae L3     Caffeine 2.5 mg/ml 48 hrs, 4-day adult     Caffeine 25 mg/ml 48 hrs, 4-day adult     Paraquat 5 mM 48 hrs, 4-day adult     Paraquat 10 mM 48 hrs, 4-day adult     Rotenone 2 μg 12 hrs, larvae L3     Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010, Graveley et al., 2011) mE2_34_mRNA_expression_cluster_05 mE1_20_mRNA_expression_cluster_10
External Data & Images
Linkouts	BDGP expression data • GM02147 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030719 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9177-RA FlyExpress - Embryonic expression images (BDGP data) • Show all FlyExpress processed images for eIF5 Stages(s) 4-6 Stages(s) 7-8 Stages(s) 11-12
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele lethal eIF5GD14146 lethal, with Scer\GAL4pnr-MD237 eIF5GD14146 lethal | larval stage eIF5G0261 lethal | pupal stage, with Scer\GAL4pnr-MD237 eIF5GD14146 Other Phenotypes Allele neuroanatomy defective | larval stage eIF5GD14146 Phenotype manifest in Allele embryonic/larval neuroblast | larval stage eIF5GD14146 ganglion mother cell | larval stage eIF5GD14146
Classical Alleles ( 2 )
For All Classical Alleles Show
Allele of eIF5 Class Mutagen Stocks Known lesion eIF5HP10800 1 -- eIF5G0261 P-element activity 0 --
Alleles Carried on Transgenic Constructs ( 4 )
For All Alleles Carried on Transgenic Constructs Show
Allele of eIF5 Class Mutagen Stocks Known lesion eIF5GD14146 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes eIF5HMS00159 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes eIF5KK102299 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes eIF5NIG.9177R in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD14146} NA P{KK102299} NA P{NIG.9177R} NA P{TRiP.HMS00159} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap P{lacW}eIF5G0261 No insertion of mobile activating element P{EPg}eIF5HP10800 NA
Gene Ontology: Function, Process & Cellular Component ( 5 unique terms )
Terms Based on Experimental Evidence ( 1 term )
Molecular Function ( 0 terms)
Biological Process
CV term Evidence References
neurogenesis inferred from mutant phenotype (Neumüller et al., 2011)
Cellular Component ( 0 terms)
Terms Based on Predictions or Assertions ( 4 terms )
Molecular Function
CV term Evidence References
translation initiation factor activity inferred from sequence or structural similarity (Lasko, 2000) inferred from sequence or structural similarity with UniProtKB:P55010 (assigned by UniProtKB) (Swiss-Prot Project Members, 2002.6.15) inferred from sequence or structural similarity with UniProtKB:Q07205 (FlyBase, 1992-)
Biological Process
CV term Evidence References
RNA metabolic process inferred from electronic annotation with InterPro:IPR016021 (FlyBase Curators et al., 2004-) translational initiation inferred from sequence or structural similarity (Lasko, 2000) inferred from sequence or structural similarity with UniProtKB:P55010 (assigned by UniProtKB) (Swiss-Prot Project Members, 2002.6.15) inferred from sequence or structural similarity with UniProtKB:Q07205 (FlyBase, 1992-)
Cellular Component
CV term Evidence References
cytosol inferred from sequence or structural similarity (Lasko, 2000) inferred from sequence or structural similarity with UniProtKB:P55010 (assigned by UniProtKB) (Swiss-Prot Project Members, 2002.6.15) inferred from sequence or structural similarity with UniProtKB:Q07205 (FlyBase, 1992-)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
protein-protein
Interacting group Assay References
eIF5 - CG5114 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eIF5 - CG9992 anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eIF5 - CkIIα anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23) eIF5 - eIF-2β anti tag coimmunoprecipitation, peptide massfingerprinting (Mintseris et al., 2009.11.23)
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions eIF5 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 58910 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030719 DroID - A comprehensive database of gene and protein interactions. • FBgn0030719 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32566
Orthologs
OrthoDB Orthologs (42) - based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
	OrthoDB orthology group searches (Waterhouse et al., 2011, Nucleic Acids Res. 39(Database issue): D283--D288) Drosophila inclusive ortholog search EOG6FFDMP Dipteran inclusive ortholog search EOG6G4GZZ Insect inclusive ortholog search EOG6Z61J2 Arthropod inclusive ortholog search EOG6Z6142 Metazoa inclusive ortholog search EOG6C8MKW
Orthologs in Drosophila Species (EOG6FFDMP)
Organism Common Name Gene AAA Syntenic Ortholog Multiple Dmel Genes in this Orthologous Group Drosophila melanogaster fruit fly  Dmel\eIF5     Drosophila simulans   Dsim\GD15766 Y   Drosophila sechellia   Dsec\GM11673 Y   Drosophila erecta   Dere\GG19351 Y   Drosophila yakuba   Dyak\eIF5 Y   Drosophila ananassae   Dana\GF20507 Y   Drosophila pseudoobscura pseudoobscura   Dpse\GA27482 Y   Drosophila persimilis   Dper\GL11549 Y   Drosophila willistoni   Dwil\GK25118 Y   Drosophila virilis   Dvir\GJ15997 Y   Drosophila mojavensis   Dmoj\GI21522 Y   Drosophila grimshawi   Dgri\GH24190 Y
Orthologs in non-Drosophila Dipterans (EOG6G4GZZ)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Aedes aegypti Yellow fever mosquito  Aaeg\AAEL000185   Anopheles gambiae Malaria mosquito  Agam\AGAP011203   Culex quinquefasciatus Southern house mosquito  Cqui\CPIJ000689
Orthologs in non-Dipteran Insects (EOG6Z61J2)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Apis mellifera Western honey bee  Amel\eIF5   Nasonia vitripennis Parasitic wasp  Nvit\Nasvi2EG012371   Acromyrmex echinatior Panamanian leafcutter ant  Aech\AECH23982   Atta cephalotes Leafcutter ant  Acep\ACEP27400   Camponotus floridanus Florida carpenter ant  Cflo\CFLO14104   Harpegnathos saltator Jerdons jumping ant  Hsal\HSAL21108   Linepithema humile Argentine ant  Lhum\LH12992   Pogonomyrmex barbatus Red harvester ant  Pbar\PB23379   Solenopsis invicta Red fire ant  Sinv\SINV21116   Acyrthosiphon pisum Pea aphid  Apim\ACYPI006141   Bombyx mori Silkmoth  Bmor\BGIBMGA008226   Pediculus humanus Human body louse  Phum\PHUM287480   Tribolium castaneum Red flour beetle  Tcas\GLEAN_07510
Orthologs in non-Insect Arthropods (EOG6Z6142)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Daphnia pulex Water flea  Dpux\JGI_V11_222844   Ixodes scapularis Deer tick  Isca\ISCW013537
Orthologs in non-Arthropod Metazoa (EOG6C8MKW)
Organism Common Name Gene Multiple Dmel Genes in this Orthologous Group Caenorhabditis elegans Nematode  Cele\C37C3.2   Strongylocentrotus purpuratus Purple sea urchin  Spur\SPU_018897gn   Danio rerio Zebrafish  Drer\eif5   Xenopus tropicalis Western clawed frog  Xtro\eif5   Gallus gallus Domestic chicken  Ggal\EIF5   Mus musculus House mouse  Mmus\Eif5   Rattus norvegicus Norway rat  Rnor\Eif5   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000023709   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000038453   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000006459   Rattus norvegicus Norway rat  Rnor\ENSRNOG00000024655   Homo sapiens Human  Hsap\EIF5
Human Orthologs (1)
Gene OMIM HGNC Hsap\EIF5
AAA Orthologs (11) based on analysis using Dmel annotation version 4.3
Organism Gene Drosophila simulans Dsim\GD15766 Drosophila sechellia Dsec\GM11673 Drosophila erecta Dere\GG19351 Drosophila yakuba Dyak\eIF5 Drosophila ananassae Dana\GF20507 Drosophila pseudoobscura pseudoobscura Dpse\GA27482 Drosophila persimilis Dper\GL11549 Drosophila willistoni Dwil\GK25118 Drosophila virilis Dvir\GJ15997 Drosophila mojavensis Dmoj\GI21522 Drosophila grimshawi Dgri\GH24190
Stocks & Reagents
Stocks Listed in FlyBase ( 5 )
Bloomington	22132 w1118 P{EPg}eIF5HP10800 34841 y1 sc* v1; P{TRiP.HMS00159}attP2
VDRC	v105992 P{KK102299}VIE-260B v29070 w1118; P{GD14146}v29070 v29071 w1118; P{GD14146}v29071
Genomic Clones ( 1 )
	BACR32K23 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 127 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	GM02147
Other clones	DPiM_GM02147 yak-ad_eIF5
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	GM31301 LD06590 LD13808 LD14291 LP11650 LP11722 RE08380 RE09774 RE12273 RE13332 RE14978 RE20251 RE20451 RE20758 RE21787 RE22848 RE25603 RE27009 RE29078 RE32314 RE32342 RE40421 RE40673 RE63001 RE64789 RE66979 RE68244 RE71883 RE73356 RE73721 RH15946 RH17922 RH29820 RH30477 RH33393 RH38257 SD02540
Other clones	17527 18560 31134 36738 53766 54349 56753 62293 69548 69875 70442 71229 82926 98938 120980 122562 157885 172934 174044 182905 191934 214217.38 214225.33 214537.45 273944 556908 AA433284 bs78c09 CK01.1B.E7 CK01.13B.G8 CK01.14A.B8 CK01.14A.C2 CK01.16A.G12 CK01.78C.G7 CK01.93B.D2 CK01.94C.F12 CK01.96B.F10 Dmel_dig_000908_0607_0453 Dmel_dig_001734_0605_0419 Dmel_dig_004793_0670_1329 Dmel_dig_005952_0643_2508 Dmel_dig_007624_0669_0986 Dmel_dig_012097_0720_0986 Dmel_dig_012795_0654_0859 Dmel_dig_019433_0581_2777 EC15008 EC35242 EK015960 EK072845 EK073754 EK130720 EK139846 EK147122 EK154139 EK169220 EK177935 EK179447 EK188110 EK196559 EK197425 EK251401 EK260626 EK287873 EK294430 EN04902 EN11650 EP03963 EP08426 EP09516 ESG019a.E21.2_H11 FGC012H06 FGC026E09 FGM320C07 GH22869 LD21517 RP004144948 RP004230797 RP004235657 RP004283930 RP004311902 RP004322909 RP004361438 RP004420318 RP004428355 RP004512108 RP004516518 RP004520568
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030719 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32566
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of	Source for identity of: eIF5 CG9177 (Lasko, 2000)
Source for database merge of	Source for merge of: CG9177 anon-EST:fe3C6 (Bayraktaroglu, 2000.11.2)
Additional comments
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132870 NM_167477 NM_206754 NM_206755 NM_206756 NM_206757 NM_206758 RefSeq (Proteins) • NP_573098 NP_727922 NP_996477 NP_996478 NP_996479 NP_996480 NP_996481 DDBJ / EMBL / GenBank • AA433284 AA695105 AAF48553 AAF48554 AAL28391 AAS65378 AAS65379 AAS65380 AAS65381 AAS65382 AW941924 AY060843 Entrez Gene - A searchable database of RefSeq genes. • 32566 UniProtKB/Swiss-Prot • Q9VXK6
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Translation initiation factor IF2/IF5 (IPR002735) W2 domain (IPR003307) Armadillo-type fold (IPR016024) Translation initiation factor IF2/IF5, N-terminal (IPR016189) MIF4-like, type 1/2/3 (IPR016021) BDGP expression data - Patterns of gene expression in Drosophila embryogenesis • GM02147
Linkouts
	BioGRID - A database of protein and genetic interactions • 58910 DPiM - DPiM, Drosophila Protein interaction Map • FBgn0030719 DroID - A comprehensive database of gene and protein interactions. • FBgn0030719 DRSC - Results from RNAi screens. • FBgn0030719 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030719 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9177-RA FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030719 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32566 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32566 modMine - Data generated by the modENCODE project. • FBgn0030719
Synonyms & Secondary IDs ( 6 )
Reported As
Symbol Synonym	anon-EST:fe3C6   CG9177 (Lasko, 2000, Keleman et al., 2009.8.5, Ni et al., 2011.7.19) eIF5 (Stuart et al., 2007, Lecuyer et al., 2007, Chew et al., 2009, Zhou et al., 2008, Japanese National Institute of Genetics, 2012.5.21) EIf5 (Davis et al., 2011) unnamed (Schmid and Tautz, 1997)
Name Synonym	anon-fast-evolving-3C6   eIF5 (Davis et al., 2011)
Secondary FlyBase IDs
	FBgn0025193
References ( 27 )
Generate a list of	All references relating to this gene ( 27 )
List References by type	Research paper  ( 7 ) Supplementary material  ( 6 ) Personal communication to FlyBase  ( 8 ) FlyBase analysis  ( 1 ) Stock list  ( 1 ) Protein sequence record  ( 1 ) Website  ( 1 ) Curated genome annotation  ( 1 )
Recent research papers ( 1 )
	Davis et al., 2011, BMC Dev. Biol. 11: 66 Identification of common and cell type specific LXXLL motif EcR cofactors using a bioinformatics refined candidate RNAi screen in Drosophila melanogaster cell lines. [FBrf0216830] Show all research papers ...