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Gene Dmel\CG9911

General Information
Symbol	Dmel\CG9911	Species	D. melanogaster
Name		Annotation symbol	CG9911
Feature type	protein_coding_gene	FlyBase ID	FBgn0030734
Gene Model Status	Current	Stock availability	4 publicly available
Genomic Location
Chromosome (arm)	X	Recombination map
Cytogenetic map	14B9-14B9	Sequence location	X:16,187,886..16,191,751 [-]
Genomic Maps Select View:Gene Models/EvidenceExpression/RegulationMegaViewGene Disruptions, Stocks and Reagents modENCODE GBrowse	Decorated FastA GenBankGFF Gene region Extended Gene region CDSIntronsExonsTranslationsTranscripts3' UTR5' UTR
Summary Information
Automatically generated summary See sections below for more information	This gene is referred to in FlyBase by the symbol Dmel\CG9911 (FBgn0030734). It is a protein_coding_gene from Drosophila melanogaster. Based on sequence similarity, it is predicted to have molecular function: protein disulfide isomerase activity. An electronic pipeline based on InterPro domains suggests that it is involved in the biological process: cell redox homeostasis. 4 alleles are reported. The phenotype of these alleles is annotated with: trichogen cell. It has 4 annotated transcripts and 4 annotated polypeptides. Protein features are: Thioredoxin domain; Thioredoxin-like fold. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed at stages throughout the larval period, during early pupal stages, in adult female stages. Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult brain, adult crop, adult fat body, adult testis, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1624499_s_at completely aligns to an exonic region common to each of the 4 FlyBase-annotated transcript isoforms of CG9911. Gene sequence location is X:16187886..16191751.
Recent Updates
Description	What does this section display? This section contains items that were added to this record for each release. It currently only tracks new links between this FlyBase report and other FlyBase data classes (e.g. genes, references, stocks) or controlled vocabulary terms (e.g. GO, anatomy terms). What does this section not display? This section does not currently display links that were removed or gene model changes.
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FB2011_10	Controlled Vocabulary Terms day 42 of adulthood day 41 of adulthood day 30 of adulthood day 49 of adulthood day 17 of adulthood day 45 of adulthood day 8 of adulthood day 26 of adulthood day 21 of adulthood day 13 of adulthood day 25 of adulthood day 20 of adulthood day 22 of adulthood day 39 of adulthood day 7 of adulthood day 36 of adulthood day 11 of adulthood day 37 of adulthood day 27 of adulthood day 18 of adulthood day 19 of adulthood day 28 of adulthood day 9 of adulthood day 29 of adulthood adult heart day 40 of adulthood day 16 of adulthood day 24 of adulthood day 15 of adulthood day 33 of adulthood day 43 of adulthood day 47 of adulthood day 38 of adulthood day 32 of adulthood day 48 of adulthood day 23 of adulthood day 35 of adulthood day 12 of adulthood day 10 of adulthood day 31 of adulthood day 34 of adulthood day 44 of adulthood day 14 of adulthood day 46 of adulthood
FB2012_01	Sequence features BKN22829 HFA20215
All updates	Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Cytogenetic map Evidence for location 14B9-14B9   Limits computationally determined from genome sequence between P{EP}kat80EP620&P{EP}cazEP1564 and P{EP}Cyp1EP1073&P{EP}Dsp1EP355
Experimentally Determined Cytological Location
Cytogenetic map Notes References
Experimentally Determined Recombination Data
Location
Left of (cM)
Right of (cM)
Notes
Gene Model & Products
Please see the GBrowse view of Dmel\CG9911 for information on other features To submit a correction to a gene model please use the Contact FlyBase form
Comments on Gene Model
Transcript Data
Annotated Transcripts
Name FlyBase ID RefSeq ID Length (nt) Associated CDS (aa) CG9911-RA FBtr0074243  NM_132883   1478   412 CG9911-RB FBtr0074242  NM_167494   1426   412 CG9911-RC FBtr0074244  NM_167496   1364   375 CG9911-RD FBtr0074241  NM_167495   1477   412
Additional Transcript Data & Comments
Reported size (kB)
Comments
External Data
Crossreferences
Polypeptide Data
Annotated Polypeptides
Name FlyBase ID Predicted MW (kDa) Length (aa) Theoretical pI RefSeq ID GenBank protein CG9911-PA   FBpp0074022   47.1   412   5.85     NP_573111   AAF48580 CG9911-PB   FBpp0074021   47.1   412   5.85     NP_727947   AAN09390 CG9911-PC   FBpp0074023   43.3   375   5.71     NP_727949   AAN09391 CG9911-PD   FBpp0074020   47.1   412   5.85     NP_727948   AAF48579
Additional Polypeptide Data & Comments
Reported size (kDa)
Comments
External Data
Linkouts
Crossreferences	InterPro domains - A database of protein families, domains, and functional sites • Thioredoxin-like fold (IPR012336) Thioredoxin domain (IPR013766)
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank	DNA sequence Protein sequence Name AA392268   AA539512   AE014298 AAF48579   AE014298 AAF48580   AE014298 AAN09390   AE014298 AAN09391   AI063842   AI134377   AI135541   AI259146   AI294071   AI515820   AI531022   AY058697 AAL13926   BF490584   BF494372   BF495252   BG632260   BG634295   BG636339   BG641268   BI640976   BI641012   CA803701   CA804064   CA804591   CA806540   CA806840   CA806943   CA807297   CA807795   CO182217   CO193671   CO264501   CO271314   CO275608   CO276357   CO279867   CO283275   CO292455   CO292478   CO299034   CO331326   EC059904   EC063642   EC064862   EC075091   EC209660   EC213619   EC220413   EC221107   EC221492   EC228081   EC233975   EC243422   EC250939   EC255776   EV578048   EV580143   EV582352   EV591646
UniProtKB/Swiss-Prot
UniProtKB/TrEMBL	Q95TL8 Q9VXI3
Mapped Features
Mapped Features have been reorganized, please see this article for details. Additional mapped features and mutations can be found on GBrowse or related reports. Type Symbol & Location Additional Notes References
External Data
Linkouts
Crossreferences
Expression Data
Transcript Expression
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
Polypeptide Expression
mass spectroscopy Stage Tissue/Position (including subcellular localization) Reference day 7 of adulthood -- day 49 of adulthood   adult heart   (Cammarato et al., 2011)
Additional Descriptive Data
Marker for
Subcellular Localization
CV Term
Notes
High-Throughput Expression Data
or
See Gelbart and Emmert, 2010.10.13 for analysis details and data files for all genes. modENCODE Temporal Expression Data for FBgn0030734    Styles Linear Logarithmic Heatmap    Scales max expr for FBgn0030734 Very low expression bin max Moderate expression bin max High expression bin max Extremely high expression bin max Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of low expression. Peak expression observed at stages throughout the larval period, during early pupal stages, in adult female stages. [download data (TSV)] Guide to modENCODE expression level colors   No expression (0 - 0)   Extremely low expression (1 - 10)   Very low expression (11 - 100)   Low expression (101 - 400)   Moderate expression (401 - 1400)   Moderately high expression (1401 - 4000)   High expression (4001 - 10000)   Very high expression (10001 - 100000)   Extremely high expression (100001 - 2000000) Linear, scaled to maximum FBgn0030734 expression level Developmental Stage   Expression Level embryo 00-02hr    3201 embryo 02-04hr    363 embryo 04-06hr    746 embryo 06-08hr    1708 embryo 08-10hr    2494 embryo 10-12hr    3775 embryo 12-14hr    3722 embryo 14-16hr    2206 embryo 16-18hr    2070 embryo 18-20hr    1690 embryo 20-22hr    1278 embryo 22-24hr    1616 larva L1    2874 larva L2    4792 larva L3 12hr old    3471 larva L3 puffstage 1-2    4692 larva L3 puffstage 3-6    4194 larva L3 puffstage 7-9    4324 white prepupae new    4150 white prepupae 12hr    2820 white prepupae 24hr    3100 pupae 2d postWPP    2356 pupae 3d postWPP    1753 pupae 4d postWPP    1525 adult male 01day    2936 adult male 05day    3604 adult male 30day    3729 adult female 01day    2479 adult female 05day    4018 adult female 30day    3967 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High  Linear, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3201) embryo 02-04hr  (363) embryo 04-06hr  (746) embryo 06-08hr  (1708) embryo 08-10hr  (2494) embryo 10-12hr  (3775) embryo 12-14hr  (3722) embryo 14-16hr  (2206) embryo 16-18hr  (2070) embryo 18-20hr  (1690) embryo 20-22hr  (1278) embryo 22-24hr  (1616) larva L1  (2874) larva L2  (4792) larva L3 12hr old  (3471) larva L3 puffstage 1-2  (4692) larva L3 puffstage 3-6  (4194) larva L3 puffstage 7-9  (4324) white prepupae new  (4150) white prepupae 12hr  (2820) white prepupae 24hr  (3100) pupae 2d postWPP  (2356) pupae 3d postWPP  (1753) pupae 4d postWPP  (1525) adult male 01day  (2936) adult male 05day  (3604) adult male 30day  (3729) adult female 01day  (2479) adult female 05day  (4018) adult female 30day  (3967) Expression Level Scale  None   Extremely low   Very low   Low  Linear, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3201) embryo 02-04hr    363 embryo 04-06hr    746 embryo 06-08hr  (1708) embryo 08-10hr  (2494) embryo 10-12hr  (3775) embryo 12-14hr  (3722) embryo 14-16hr  (2206) embryo 16-18hr  (2070) embryo 18-20hr  (1690) embryo 20-22hr    1278 embryo 22-24hr  (1616) larva L1  (2874) larva L2  (4792) larva L3 12hr old  (3471) larva L3 puffstage 1-2  (4692) larva L3 puffstage 3-6  (4194) larva L3 puffstage 7-9  (4324) white prepupae new  (4150) white prepupae 12hr  (2820) white prepupae 24hr  (3100) pupae 2d postWPP  (2356) pupae 3d postWPP  (1753) pupae 4d postWPP  (1525) adult male 01day  (2936) adult male 05day  (3604) adult male 30day  (3729) adult female 01day  (2479) adult female 05day  (4018) adult female 30day  (3967) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  Linear, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3201 embryo 02-04hr    363 embryo 04-06hr    746 embryo 06-08hr    1708 embryo 08-10hr    2494 embryo 10-12hr    3775 embryo 12-14hr    3722 embryo 14-16hr    2206 embryo 16-18hr    2070 embryo 18-20hr    1690 embryo 20-22hr    1278 embryo 22-24hr    1616 larva L1    2874 larva L2    4792 larva L3 12hr old    3471 larva L3 puffstage 1-2    4692 larva L3 puffstage 3-6    4194 larva L3 puffstage 7-9    4324 white prepupae new    4150 white prepupae 12hr    2820 white prepupae 24hr    3100 pupae 2d postWPP    2356 pupae 3d postWPP    1753 pupae 4d postWPP    1525 adult male 01day    2936 adult male 05day    3604 adult male 30day    3729 adult female 01day    2479 adult female 05day    4018 adult female 30day    3967 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  Linear, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3201 embryo 02-04hr    363 embryo 04-06hr    746 embryo 06-08hr    1708 embryo 08-10hr    2494 embryo 10-12hr    3775 embryo 12-14hr    3722 embryo 14-16hr    2206 embryo 16-18hr    2070 embryo 18-20hr    1690 embryo 20-22hr    1278 embryo 22-24hr    1616 larva L1    2874 larva L2    4792 larva L3 12hr old    3471 larva L3 puffstage 1-2    4692 larva L3 puffstage 3-6    4194 larva L3 puffstage 7-9    4324 white prepupae new    4150 white prepupae 12hr    2820 white prepupae 24hr    3100 pupae 2d postWPP    2356 pupae 3d postWPP    1753 pupae 4d postWPP    1525 adult male 01day    2936 adult male 05day    3604 adult male 30day    3729 adult female 01day    2479 adult female 05day    4018 adult female 30day    3967 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  log, scaled to maximum FBgn0030734 expression level Developmental Stage   Expression Level embryo 00-02hr    3201 embryo 02-04hr    363 embryo 04-06hr    746 embryo 06-08hr    1708 embryo 08-10hr    2494 embryo 10-12hr    3775 embryo 12-14hr    3722 embryo 14-16hr    2206 embryo 16-18hr    2070 embryo 18-20hr    1690 embryo 20-22hr    1278 embryo 22-24hr    1616 larva L1    2874 larva L2    4792 larva L3 12hr old    3471 larva L3 puffstage 1-2    4692 larva L3 puffstage 3-6    4194 larva L3 puffstage 7-9    4324 white prepupae new    4150 white prepupae 12hr    2820 white prepupae 24hr    3100 pupae 2d postWPP    2356 pupae 3d postWPP    1753 pupae 4d postWPP    1525 adult male 01day    2936 adult male 05day    3604 adult male 30day    3729 adult female 01day    2479 adult female 05day    4018 adult female 30day    3967 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Very low expression Developmental Stage   Expression Level embryo 00-02hr  (3201) embryo 02-04hr  (363) embryo 04-06hr  (746) embryo 06-08hr  (1708) embryo 08-10hr  (2494) embryo 10-12hr  (3775) embryo 12-14hr  (3722) embryo 14-16hr  (2206) embryo 16-18hr  (2070) embryo 18-20hr  (1690) embryo 20-22hr  (1278) embryo 22-24hr  (1616) larva L1  (2874) larva L2  (4792) larva L3 12hr old  (3471) larva L3 puffstage 1-2  (4692) larva L3 puffstage 3-6  (4194) larva L3 puffstage 7-9  (4324) white prepupae new  (4150) white prepupae 12hr  (2820) white prepupae 24hr  (3100) pupae 2d postWPP  (2356) pupae 3d postWPP  (1753) pupae 4d postWPP  (1525) adult male 01day  (2936) adult male 05day  (3604) adult male 30day  (3729) adult female 01day  (2479) adult female 05day  (4018) adult female 30day  (3967) Expression Level Scale  None   Extremely low   Very low   Low  log, scaled to Moderate expression Developmental Stage   Expression Level embryo 00-02hr  (3201) embryo 02-04hr    363 embryo 04-06hr    746 embryo 06-08hr  1708 embryo 08-10hr  (2494) embryo 10-12hr  (3775) embryo 12-14hr  (3722) embryo 14-16hr  2206 embryo 16-18hr  2070 embryo 18-20hr  1690 embryo 20-22hr    1278 embryo 22-24hr  1616 larva L1  (2874) larva L2  (4792) larva L3 12hr old  (3471) larva L3 puffstage 1-2  (4692) larva L3 puffstage 3-6  (4194) larva L3 puffstage 7-9  (4324) white prepupae new  (4150) white prepupae 12hr  (2820) white prepupae 24hr  (3100) pupae 2d postWPP  2356 pupae 3d postWPP  1753 pupae 4d postWPP  1525 adult male 01day  (2936) adult male 05day  (3604) adult male 30day  (3729) adult female 01day  (2479) adult female 05day  (4018) adult female 30day  (3967) Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high  log, scaled to High expression Developmental Stage   Expression Level embryo 00-02hr    3201 embryo 02-04hr    363 embryo 04-06hr    746 embryo 06-08hr    1708 embryo 08-10hr    2494 embryo 10-12hr    3775 embryo 12-14hr    3722 embryo 14-16hr    2206 embryo 16-18hr    2070 embryo 18-20hr    1690 embryo 20-22hr    1278 embryo 22-24hr    1616 larva L1    2874 larva L2    4792 larva L3 12hr old    3471 larva L3 puffstage 1-2    4692 larva L3 puffstage 3-6    4194 larva L3 puffstage 7-9    4324 white prepupae new    4150 white prepupae 12hr    2820 white prepupae 24hr    3100 pupae 2d postWPP    2356 pupae 3d postWPP    1753 pupae 4d postWPP    1525 adult male 01day    2936 adult male 05day    3604 adult male 30day    3729 adult female 01day    2479 adult female 05day    4018 adult female 30day    3967 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high  log, scaled to Extremely high expression Developmental Stage   Expression Level embryo 00-02hr    3201 embryo 02-04hr    363 embryo 04-06hr    746 embryo 06-08hr    1708 embryo 08-10hr    2494 embryo 10-12hr    3775 embryo 12-14hr    3722 embryo 14-16hr    2206 embryo 16-18hr    2070 embryo 18-20hr    1690 embryo 20-22hr    1278 embryo 22-24hr    1616 larva L1    2874 larva L2    4792 larva L3 12hr old    3471 larva L3 puffstage 1-2    4692 larva L3 puffstage 3-6    4194 larva L3 puffstage 7-9    4324 white prepupae new    4150 white prepupae 12hr    2820 white prepupae 24hr    3100 pupae 2d postWPP    2356 pupae 3d postWPP    1753 pupae 4d postWPP    1525 adult male 01day    2936 adult male 05day    3604 adult male 30day    3729 adult female 01day    2479 adult female 05day    4018 adult female 30day    3967 Expression Level Scale  None   Extremely low   Very low   Low   Moderate   Moderately high   High   Very high   Extremely high  Heatmap Developmental Stage   Expression Level embryo 00-02hr     embryo 02-04hr     embryo 04-06hr     embryo 06-08hr     embryo 08-10hr     embryo 10-12hr     embryo 12-14hr     embryo 14-16hr     embryo 16-18hr     embryo 18-20hr     embryo 20-22hr     embryo 22-24hr     larva L1     larva L2     larva L3 12hr old     larva L3 puffstage 1-2     larva L3 puffstage 3-6     larva L3 puffstage 7-9     white prepupae new     white prepupae 12hr     white prepupae 24hr     pupae 2d postWPP     pupae 3d postWPP     pupae 4d postWPP     adult male 01day     adult male 05day     adult male 30day     adult female 01day     adult female 05day     adult female 30day     FlyAtlas Anatomical Expression Data for FBgn0030734    Styles Linear Logarithmic Heatmap Back-to-back    Scales max expr for FBgn0030734 Moderate expression bin max High level expression bin max Very high expression bin max Summary of FlyAtlas Anatomical Expression Data: High or moderate levels of expression observed in all larval and adult organs/tissues. Expression at high levels in the following post-embryonic organs or tissues: adult head, adult eye, larval/adult central nervous system, larval/adult midgut, larval/adult hindgut, larval/adult Malpighian tubules, adult heart, larval fat body, larval/adult salivary gland, larval trachea, adult female reproductive system, adult male accessory gland, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult brain, adult crop, adult fat body, adult testis, adult carcass. [download data (TSV)] Guide to FlyAtlas expression level colors   No expression (0 - 9.999)   Low expression (10 - 99.999)   Moderate expression (100 - 499.999)   High level expression (500 - 999.999)   Very high expression (1000 - 25000) Linear, scaled to maximum FBgn0030734 expression level Tissue   Expression Level Larval Central Nervous System    519.325 Larval Midgut    832.8 Larval Hindgut    689.5 Larval Malpighian Tubules    544.7 Larval Fat Body    592.6 Larval Salivary Gland    4709 Larval Trachea    753.925 Larval Carcass    674.875 Adult Head    576.7 Adult Eye    754.375 Adult Brain    466.5 Adult Thoracic-Abdominal Ganglion    541.3 Adult Crop    489.9 Adult Midgut    788.2 Adult Hindgut    635.6 Adult Malpighian Tubules    515.1 Adult Fat Body    495.9 Adult Salivary Gland    3148.1 Adult Heart    556.425 Adult VirginFemale Spermatheca    1126.4 Adult InseminatedFemale Spermatheca    1255.4 Adult Ovary    595.2 Adult Testis    228 Adult Male Accessory Gland    3285.6 Adult Carcass    422.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  519.325 Larval Midgut  (832.8) Larval Hindgut  (689.5) Larval Malpighian Tubules  (544.7) Larval Fat Body  (592.6) Larval Salivary Gland  (4709) Larval Trachea  (753.925) Larval Carcass  (674.875) Adult Head  (576.7) Adult Eye  (754.375) Adult Brain    466.5 Adult Thoracic-Abdominal Ganglion  (541.3) Adult Crop    489.9 Adult Midgut  (788.2) Adult Hindgut  (635.6) Adult Malpighian Tubules  515.1 Adult Fat Body    495.9 Adult Salivary Gland  (3148.1) Adult Heart  (556.425) Adult VirginFemale Spermatheca  (1126.4) Adult InseminatedFemale Spermatheca  (1255.4) Adult Ovary  (595.2) Adult Testis    228 Adult Male Accessory Gland  (3285.6) Adult Carcass    422.5 Expression Level Scale  None   Low   Moderate   High  Linear, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    519.325 Larval Midgut    832.8 Larval Hindgut    689.5 Larval Malpighian Tubules    544.7 Larval Fat Body    592.6 Larval Salivary Gland  (4709) Larval Trachea    753.925 Larval Carcass    674.875 Adult Head    576.7 Adult Eye    754.375 Adult Brain    466.5 Adult Thoracic-Abdominal Ganglion    541.3 Adult Crop    489.9 Adult Midgut    788.2 Adult Hindgut    635.6 Adult Malpighian Tubules    515.1 Adult Fat Body    495.9 Adult Salivary Gland  (3148.1) Adult Heart    556.425 Adult VirginFemale Spermatheca  (1126.4) Adult InseminatedFemale Spermatheca  (1255.4) Adult Ovary    595.2 Adult Testis    228 Adult Male Accessory Gland  (3285.6) Adult Carcass    422.5 Expression Level Scale  None   Low   Moderate   High   Very high  Linear, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    519.325 Larval Midgut    832.8 Larval Hindgut    689.5 Larval Malpighian Tubules    544.7 Larval Fat Body    592.6 Larval Salivary Gland    4709 Larval Trachea    753.925 Larval Carcass    674.875 Adult Head    576.7 Adult Eye    754.375 Adult Brain    466.5 Adult Thoracic-Abdominal Ganglion    541.3 Adult Crop    489.9 Adult Midgut    788.2 Adult Hindgut    635.6 Adult Malpighian Tubules    515.1 Adult Fat Body    495.9 Adult Salivary Gland    3148.1 Adult Heart    556.425 Adult VirginFemale Spermatheca    1126.4 Adult InseminatedFemale Spermatheca    1255.4 Adult Ovary    595.2 Adult Testis    228 Adult Male Accessory Gland    3285.6 Adult Carcass    422.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to maximum FBgn0030734 expression level Tissue   Expression Level Larval Central Nervous System    519.325 Larval Midgut    832.8 Larval Hindgut    689.5 Larval Malpighian Tubules    544.7 Larval Fat Body    592.6 Larval Salivary Gland    4709 Larval Trachea    753.925 Larval Carcass    674.875 Adult Head    576.7 Adult Eye    754.375 Adult Brain    466.5 Adult Thoracic-Abdominal Ganglion    541.3 Adult Crop    489.9 Adult Midgut    788.2 Adult Hindgut    635.6 Adult Malpighian Tubules    515.1 Adult Fat Body    495.9 Adult Salivary Gland    3148.1 Adult Heart    556.425 Adult VirginFemale Spermatheca    1126.4 Adult InseminatedFemale Spermatheca    1255.4 Adult Ovary    595.2 Adult Testis    228 Adult Male Accessory Gland    3285.6 Adult Carcass    422.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Moderate expression Tissue   Expression Level Larval Central Nervous System  519.325 Larval Midgut  (832.8) Larval Hindgut  689.5 Larval Malpighian Tubules  544.7 Larval Fat Body  592.6 Larval Salivary Gland  (4709) Larval Trachea  753.925 Larval Carcass  674.875 Adult Head  576.7 Adult Eye  754.375 Adult Brain    466.5 Adult Thoracic-Abdominal Ganglion  541.3 Adult Crop    489.9 Adult Midgut  788.2 Adult Hindgut  635.6 Adult Malpighian Tubules  515.1 Adult Fat Body    495.9 Adult Salivary Gland  (3148.1) Adult Heart  556.425 Adult VirginFemale Spermatheca  (1126.4) Adult InseminatedFemale Spermatheca  (1255.4) Adult Ovary  595.2 Adult Testis    228 Adult Male Accessory Gland  (3285.6) Adult Carcass    422.5 Expression Level Scale  None   Low   Moderate   High  log, scaled to High level expression Tissue   Expression Level Larval Central Nervous System    519.325 Larval Midgut    832.8 Larval Hindgut    689.5 Larval Malpighian Tubules    544.7 Larval Fat Body    592.6 Larval Salivary Gland  (4709) Larval Trachea    753.925 Larval Carcass    674.875 Adult Head    576.7 Adult Eye    754.375 Adult Brain    466.5 Adult Thoracic-Abdominal Ganglion    541.3 Adult Crop    489.9 Adult Midgut    788.2 Adult Hindgut    635.6 Adult Malpighian Tubules    515.1 Adult Fat Body    495.9 Adult Salivary Gland  (3148.1) Adult Heart    556.425 Adult VirginFemale Spermatheca  1126.4 Adult InseminatedFemale Spermatheca  1255.4 Adult Ovary    595.2 Adult Testis    228 Adult Male Accessory Gland  (3285.6) Adult Carcass    422.5 Expression Level Scale  None   Low   Moderate   High   Very high  log, scaled to Very high expression Tissue   Expression Level Larval Central Nervous System    519.325 Larval Midgut    832.8 Larval Hindgut    689.5 Larval Malpighian Tubules    544.7 Larval Fat Body    592.6 Larval Salivary Gland    4709 Larval Trachea    753.925 Larval Carcass    674.875 Adult Head    576.7 Adult Eye    754.375 Adult Brain    466.5 Adult Thoracic-Abdominal Ganglion    541.3 Adult Crop    489.9 Adult Midgut    788.2 Adult Hindgut    635.6 Adult Malpighian Tubules    515.1 Adult Fat Body    495.9 Adult Salivary Gland    3148.1 Adult Heart    556.425 Adult VirginFemale Spermatheca    1126.4 Adult InseminatedFemale Spermatheca    1255.4 Adult Ovary    595.2 Adult Testis    228 Adult Male Accessory Gland    3285.6 Adult Carcass    422.5 Expression Level Scale  None   Low   Moderate   High   Very high  Heatmap Tissue   Expression Level Larval Central Nervous System     Larval Midgut     Larval Hindgut     Larval Malpighian Tubules     Larval Fat Body     Larval Salivary Gland     Larval Trachea     Larval Carcass     Adult Head     Adult Eye     Adult Brain     Adult Thoracic-Abdominal Ganglion     Adult Crop     Adult Midgut     Adult Hindgut     Adult Malpighian Tubules     Adult Fat Body     Adult Salivary Gland     Adult Heart     Adult VirginFemale Spermatheca     Adult InseminatedFemale Spermatheca     Adult Ovary     Adult Testis     Adult Male Accessory Gland     Adult Carcass     FlyAtlas Organ/Tissue Expression, larval vs. adult Larval Expression Level Tissue Adult Expression Level   NA  Head    576.7   NA  Eye    754.375   NA  Brain    466.5   519.325  Central Nervous System    NA   NA  Thoracic-Abdominal Ganglion    541.3   NA  Crop    489.9   832.8  Midgut    788.2   689.5  Hindgut    635.6   544.7  Malpighian Tubules    515.1   592.6  Fat Body    495.9   4709  Salivary Gland    3148.1   NA  Heart    556.425   753.925  Trachea    NA   NA  VirginFemale Spermatheca    1126.4   NA  InseminatedFemale Spermatheca    1255.4   NA  Ovary    595.2   NA  Testis    228   NA  Male Accessory Gland    3285.6   674.875  Carcass    422.5 modENCODE Temporal Expression Data (Graveley et al., 2011) FlyAtlas Anatomical Expression Data (Chintapalli et al., 2007)
Expression Clusters
	A cluster of genes with similar mRNA expression dynamics across development. (The modENCODE Consortium, 2010) mE2_34_mRNA_expression_cluster_02
External Data & Images
Linkouts	FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030734 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9911-RB
Alleles & Phenotypes
Summary of Allele Phenotypes
Lethality Allele viable, with Scer\GAL4pnr-MD237 CG9911GD14718 Other Phenotypes Allele visible, with Scer\GAL4pnr-MD237 CG9911GD14718 Phenotype manifest in Allele chaeta | supernumerary, with Scer\GAL4pnr-MD237 CG9911GD14718 trichogen cell, with Scer\GAL4pnr-MD237 CG9911GD14718
Classical Alleles ( 1 )
For All Classical Alleles Show
Allele of CG9911 Class Mutagen Stocks Known lesion CG9911MB03514 1 --
Alleles Carried on Transgenic Constructs ( 3 )
For All Alleles Carried on Transgenic Constructs Show
Allele of CG9911 Class Mutagen Stocks Known lesion CG9911GD14718 in vitro construct - RNAi in vitro construct - regulatory fusion 2 Yes CG9911JF03285 in vitro construct - RNAi in vitro construct - regulatory fusion 1 Yes CG9911KK102733 in vitro construct - RNAi in vitro construct - regulatory fusion 0 Yes
Aneuploid Aberrations
Transgenic Constructs & Insertions
Transgenic Constructs
	Type of construct Name Expression data UAS construct P{GD14718} NA P{KK102733} NA P{TRiP.JF03285} NA
Insertions
	Type of insertions Name Expression data insertion of enhancer trap binary system Mi{ET1}CG3632MB03514 No
Gene Ontology: Function, Process & Cellular Component ( 2 unique terms )
Terms Based on Experimental Evidence ( 0 terms )
Terms Based on Predictions or Assertions ( 2 terms )
Molecular Function
CV term Evidence References
protein disulfide isomerase activity inferred from sequence or structural similarity with UniProtKB:P08003 (FlyBase, 1992-)
Biological Process
CV term Evidence References
cell redox homeostasis inferred from electronic annotation with InterPro:IPR013766 (FlyBase Curators et al., 2004-)
Cellular Component ( 0 terms)
Sequence Ontology: Class of Gene
	nuclear_gene   protein_coding_gene
Interactions & Pathways
Summary of Physical Interactions
Protein-protein
Interacting group Assay References
Summary of Genetic Interactions
Interacts with	Please look at the allele data for full details of the genetic interactions CG9911 allele Gene References
External Data
Linkouts	BioGRID - A database of protein and genetic interactions • 58929 DroID - A comprehensive database of gene and protein interactions. • FBgn0030734 InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32588
Orthologs
Genome-wide drosophilid orthologs	Dana\GF19631 Dere\GG19336 Dgri\GH12152 Dmoj\GI10898 Dper\GL21325 Dpse\GA22116 Dsec\GM13413 Dsim\GD15757 Dvir\GJ18544 Dwil\GK25202 Dyak\GE11008
Curated drosophilid orthologs	Dpse\GA22116
Linkouts	InParanoid A subset of ortholog calls from InParanoid. • AAEL013845-PA Aedes aegypti (mosquito) AGAP000909-PA Anopheles gambiae (mosquito) XP_624571.1 Apis mellifera (honey bee) XP_001951494.1 Acyrthosiphon pisum (pea aphid) 122706 Branchiostoma floridae (lancelet) XP_001893038.1 Brugia malayi (roundworm nematode) BGIBMGA006941-PA Bombyx mori (silk worm) ENSBTAP00000012930 Bos taurus (bovine) CN10390 Caenorhabditis brenneri (small nematode) CBP34139 Caenorhabditis briggsae (nematode) CE39231 Caenorhabditis elegans (worm) ENSCAFP00000003711 Canis familiaris (dog) ENSCINP00000002784 Ciona intestinalis (sea squirt) JA13231 Caenorhabditis japonica (nematode) ENSCPOP00000007513 Cavia porcellus (guinea pig) RP48848 Caenorhabditis remanei (nematode) ENSCSAVP00000009331 Ciona savignyi (sedentary tunicate) 163818 Capitella spl (polychaete worm) 306744 Daphnia pulex (daphnia) ENSDARP00000017258 Danio rerio (zebra fish) ENSECAP00000014729 Equus caballus (horse) ENSGACP00000011945 Gymnopilus aculeatus (mushroom) ENSGALP00000021892 Gallus gallus (chicken) 106306 Hypsipyla robusta (cedar shoot borer) ENSP00000262455 Homo sapiens (human) 131935 Lottia gigantea (owl limpet) 39286 Monocosta brevicollis (choanoflagellate) ENSMODP00000015815 Monodelphis domestica (gray opossum) ENSMMUP00000014978 Macaca mulatta (rhesus monkey) ENSMUSP00000030028 Mus musculus (house mouse) 237233 Nematostella vectensis (starlet anemone) XP_001606135.1 Nasonia vitripennis (wasp) ENSOANP00000003368 Ornithorynchus anatinus (platypus) ENSORLP00000011021 Oryzias latipes (japanese killifish) PHUM004181-PA Pediculus humanus (human body louse) PP28269 Pristionchus pacificus (nematode) ENSPPYP00000021788 Pongo pygmaeus (orangutan) ENSPTRP00000036210 Pan troglodytes (chimpanzee) ENSRNOP00000007711 Rattus norvegicus (norway rat) Smp_144840 Schistosoma mansoni (trematode parasite) XP_791945.2 Strongylocentrotus purpuratus (purple sea urchin) 37324 Trichoplax adhaerens (metazoa) XP_971182.1 Tribolium castaneum (red flour beetle) ENSTNIP00000021547 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000027695 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000028634 Xenopus tropicalis (frog) OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16587 NV12528 LH21272 FBgn0228837 FBgn0227161 FBgn0225665 FBgn0205702 FBgn0187418 FBgn0168344 JGI_V11_306744 FBgn0082097 FBgn0158918 FBgn0133661 FBgn0119631 FBgn0111540 FBgn0096638 CPIJ017364 BGIBMGA006941 ACYPI000119 GB19276 AGAP000909 AAEL013845 PHUM174960 GLEAN_01643
Stocks & Reagents
Stocks Listed in FlyBase ( 4 )
Bloomington	29606 y1 v1; P{TRiP.JF03285}attP2 23850 w1118 Mi{ET1}CG3632MB03514 CG9911MB03514
VDRC	v46585 w1118; P{GD14718}v46585 v46586 w1118; P{GD14718}v46586
Genomic Clones ( 2 )
	BACR06P10 BACR13G13 Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
cDNA Clones ( 55 )
	Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see GBrowse for alignment of the cDNAs and ESTs to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones	LD41494
Other clones
cDNA Clones, End Sequenced (ESTs)
BDGP DGC clones	AT02841 AT04138 AT27088 AT30453 GH03941 GH05818 GH11826 GH13340 LD11284 LD17676 LP02490 LP07364 SD01876 SD12576 SD13981 SD24028 SD24071
Other clones	17328 21381 28420 43548 71852 71950 102206 214479.35 272515 273302 CK01.141D.A4 CK01.147B.D9 CK01.167C.C5 Dmel_dig_013189_0647_3300 Dmel_dig_014374_0583_2821 Dmel_dig_018076_0725_0541 Dmel_neb_013962_0335_1250 EC22281 EC36604 EK103011 EK118034 EK120615 EK136226 EK139426 EK162744 EK174357 EK200225 EK200258 EK299252 ESG013d.E21_E04 ESG015b.E21_B09 ESG015c.E21.1_G10 ESG017b.E21_E01 ESG019c.E21_E09 ESG0110a.E21_G05 ESG0111d.B21.1_G02 ESG0114b.B21_E04
RNAi & Array Information
Linkouts	DRSC - Results from RNAi screens. • FBgn0030734 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32588
Antibody Information
Other Information
Discoverer
Etymology
Identification
Relationship to Other Genes
Source for database identity of
Source for database merge of	Source for merge of: CG9911 CG9912 (FlyBase, 1996-)
Additional comments	Source for merge of CG9911 CG9912 was sequence comparison (date:001104). (FlyBase, 1996-)
Other Comments
External Crossreferences & Linkouts
Sequence Crossreferences
	RefSeq (Transcripts) • NM_132883 NM_167494 NM_167495 NM_167496 RefSeq (Proteins) • NP_573111 NP_727947 NP_727948 NP_727949 DDBJ / EMBL / GenBank • AAF48579 AAF48580 AAL13926 AAN09390 AAN09391 AI515820 AY058697 Entrez Gene - A searchable database of RefSeq genes. • 32588 UniProtKB/TrEMBL • Q9VXI3 Q95TL8
Other Crossreferences
	InterPro domains - A database of protein families, domains, and functional sites • Thioredoxin-like fold (IPR012336) Thioredoxin domain (IPR013766)
Linkouts
	BioGRID - A database of protein and genetic interactions • 58929 DroID - A comprehensive database of gene and protein interactions. • FBgn0030734 DRSC - Results from RNAi screens. • FBgn0030734 FLIGHT - Cell culture data for RNAi and other high-throughput technologies • FBgn0030734 FlyAtlas - Adult expression by tissue, using Affymetrix Dros2 array • CG9911-RB FlyMine - Integrated genomics database for Drosophila, Anopheles, and C.elegans • FBgn0030734 GenomeRNAi - GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents • 32588 InParanoid A subset of ortholog calls from InParanoid. • AAEL013845-PA Aedes aegypti (mosquito) AGAP000909-PA Anopheles gambiae (mosquito) XP_624571.1 Apis mellifera (honey bee) XP_001951494.1 Acyrthosiphon pisum (pea aphid) 122706 Branchiostoma floridae (lancelet) XP_001893038.1 Brugia malayi (roundworm nematode) BGIBMGA006941-PA Bombyx mori (silk worm) ENSBTAP00000012930 Bos taurus (bovine) CN10390 Caenorhabditis brenneri (small nematode) CBP34139 Caenorhabditis briggsae (nematode) CE39231 Caenorhabditis elegans (worm) ENSCAFP00000003711 Canis familiaris (dog) ENSCINP00000002784 Ciona intestinalis (sea squirt) JA13231 Caenorhabditis japonica (nematode) ENSCPOP00000007513 Cavia porcellus (guinea pig) RP48848 Caenorhabditis remanei (nematode) ENSCSAVP00000009331 Ciona savignyi (sedentary tunicate) 163818 Capitella spl (polychaete worm) 306744 Daphnia pulex (daphnia) ENSDARP00000017258 Danio rerio (zebra fish) ENSECAP00000014729 Equus caballus (horse) ENSGACP00000011945 Gymnopilus aculeatus (mushroom) ENSGALP00000021892 Gallus gallus (chicken) 106306 Hypsipyla robusta (cedar shoot borer) ENSP00000262455 Homo sapiens (human) 131935 Lottia gigantea (owl limpet) 39286 Monocosta brevicollis (choanoflagellate) ENSMODP00000015815 Monodelphis domestica (gray opossum) ENSMMUP00000014978 Macaca mulatta (rhesus monkey) ENSMUSP00000030028 Mus musculus (house mouse) 237233 Nematostella vectensis (starlet anemone) XP_001606135.1 Nasonia vitripennis (wasp) ENSOANP00000003368 Ornithorynchus anatinus (platypus) ENSORLP00000011021 Oryzias latipes (japanese killifish) PHUM004181-PA Pediculus humanus (human body louse) PP28269 Pristionchus pacificus (nematode) ENSPPYP00000021788 Pongo pygmaeus (orangutan) ENSPTRP00000036210 Pan troglodytes (chimpanzee) ENSRNOP00000007711 Rattus norvegicus (norway rat) Smp_144840 Schistosoma mansoni (trematode parasite) XP_791945.2 Strongylocentrotus purpuratus (purple sea urchin) 37324 Trichoplax adhaerens (metazoa) XP_971182.1 Tribolium castaneum (red flour beetle) ENSTNIP00000021547 Tetraodon nigroviridis (green spotted pufferfish) ENSTRUP00000027695 Takifugu rubripes (pufferfish Takifugu) ENSXETP00000028634 Xenopus tropicalis (frog) InterologFinder Protein-protein interactions (PPI) from both known and predicted PPI data sets. • 32588 modMine - Data generated by the modENCODE project. • FBgn0030734 OrthoDB (Arthropod subset) The hierarchical catalog of eukaryotic orthologs. • PB16587 NV12528 LH21272 FBgn0228837 FBgn0227161 FBgn0225665 FBgn0205702 FBgn0187418 FBgn0168344 JGI_V11_306744 FBgn0082097 FBgn0158918 FBgn0133661 FBgn0119631 FBgn0111540 FBgn0096638 CPIJ017364 BGIBMGA006941 ACYPI000119 GB19276 AGAP000909 AAEL013845 PHUM174960 GLEAN_01643
Synonyms & Secondary IDs ( 3 )
Reported As
Symbol Synonym	CG9911 (Legube et al., 2006, Gruber and Long, 2009, Perkins et al., 2009, Keleman et al., 2009.8.5, Cammarato et al., 2011) CG9912   LD41494p (Clissold and Bicknell, 2003)
Name Synonym
Secondary FlyBase IDs
	FBgn0030736
References ( 17 )
Research paper	Gruber and Long, 2009, Genetics 181(2): 661--670 Cis-regulatory Variation Is Typically Polyallelic in Drosophila. [FBrf0207347] Legube et al., 2006, Genes Dev. 20(7): 871--883 X-chromosome-wide profiling of MSL-1 distribution and dosage compensation in Drosophila. [FBrf0190549]
Supplementary material	Cammarato et al., 2011, PLoS ONE 6(4): Table S1. Proteins & Peptides. [FBrf0214682] The modENCODE Consortium, 2010, Science 330(6012): DataS14: Gene co-expression clusters. [FBrf0213979] Mummery-Widmer et al., 2009, Nature 458(7241): Supplementary Table 2 - Genome-wide bristle screen results. [FBrf0214518] Giot et al., 2003, Science 302(5651): Tables S1 to S7. [FBrf0166452]
Review	Clissold and Bicknell, 2003, BioEssays 25(6): 603--611 The thioredoxin-like fold: hidden domains in protein disulfide isomerase and other chaperone proteins. [FBrf0159916]
Personal communication to FlyBase	Keleman et al., 2009.8.5, RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi-phiC31 construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0208510] Perkins et al., 2009, Update to TRiP stock collection. Update to TRiP stock collection. [FBrf0208864] Bellen, 2007.5.7, batch741.xml batch741.xml [FBrf0199562] Dickson et al., 2007.7.18, RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center RNAi construct and insertion data submitted by the Vienna Drosophila RNAi Center [FBrf0200327] FlyBase Curators et al., 2004-, Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. Gene Ontology annotation in FlyBase through association of InterPro records with GO terms. [FBrf0174215]
FlyBase analysis	FlyBase, 1996-, FlyBase inference based on genome sequence analysis. FlyBase inference based on genome sequence analysis. [FBrf0104946] FlyBase, 1992-, FlyBase curation FlyBase curation. [FBrf0105495]
Computer file	BDGP Project Members, 2000-, Berkeley Drosophila Genome Project. Berkeley Drosophila Genome Project. [FBrf0125078]
Curated genome annotation	Beasley, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126653]
Automatic genome annotation	FamiliarityBreedsContempt, 1999.11, [Annotations performed at the Celera Jamboreee.] [Annotations performed at the Celera Jamboreee.] [FBrf0126705]