General Information Symbol Dmel\ AnxB11Species D. melanogaster Name Annexin B11 Annotation symbol CG9968 Feature type protein_coding_gene FlyBase ID FBgn0030749 Gene Model Status Current Stock availability 6 publicly
available Also Known As AnxB11 Genomic Location Chromosome (arm) X Recombination map Cytogenetic map 14C4-14C4 Sequence location X:16,310,991..16,316,298 [-]
Genomic Maps
Summary Information Automatically generated summary
See sections below for more information The gene
Annexin B11 is referred to in FlyBase by the symbol
Dmel\AnxB11 (CG9968, FBgn0030749). It is a protein_coding_gene from
Drosophila melanogaster . Based on sequence similarity, it is predicted to have
molecular function : actin binding. There is experimental evidence that it is involved in the
biological process : regulation of cell shape; cell adhesion.
6 alleles are reported . No phenotypic data is available. It has
7 annotated transcripts and
7 annotated polypeptides .
Protein features are: Annexin; Annexin repeat; Annexin repeat, conserved site. Summary of modENCODE Temporal Expression Profile: Temporal profile ranges from a peak of high expression to a trough of moderately high expression. Peak expression observed within 06-24 hour embryonic stages, during early larval stages, at stages throughout the pupal period. Summary of FlyAtlas Anatomical Expression Data: Nearly all larval and adult organs/tissues expressed at moderate or high levels. Expression at high levels in the following post-embryonic organs or tissues: larval central nervous system, larval hindgut, larval Malpighian tubules, larval fat body, larval/adult salivary gland, larval trachea, adult male accessory gland, larval carcass. Expression at moderate levels in the following post-embryonic organs or tissues: adult head, adult eye, adult central nervous system, adult crop, larval/adult midgut, adult hindgut, adult Malpighian tubules, adult heart, adult fat body, adult female reproductive system, adult carcass. Comments on Affy2 ProbeSet: ProbeSet 1625145_a_at completely aligns to an exonic region common to each of the 2 FlyBase-annotated transcript isoforms of Anxb11. Gene sequence location is
X:16310991..16316298 .
User Contributed Data
Recent Updates
Description
What does this section display?
This section contains items that were added to this record for each release.
It currently only tracks new links between this FlyBase report and other
FlyBase data classes (e.g. genes, references, stocks) or controlled
vocabulary terms (e.g. GO, anatomy terms).
What does this section not display?
This section does not currently display links that were removed or gene model changes.
Update Feed
Click the icon below to subscribe to this FlyBase record and receive updates automatically through your
feed reader .
FB2013_03
FB2013_02
All updates
Click here to see a list of all updates to this record from FB2010_08 and on.
Detailed Mapping Data
FlyBase Computed Cytological Location
Experimentally Determined Cytological Location
Experimentally Determined Recombination Data
Location Left of (cM) Right of (cM) Notes Gene Model & Products Comments on Gene
Model Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.46
Transcript Data Annotated Transcripts Additional Transcript Data
& Comments Reported size (kB) Comments External Data Crossreferences
Polypeptide Data Annotated
Polypeptides Additional Polypeptide
Data & Comments Reported size (kDa) Comments External Data Linkouts Crossreferences
domains - A database of protein families, domains, and functional sites
Sequences Consistent with the Gene Model
DDBJ / EMBL / GenBank UniProtKB/Swiss-Prot UniProtKB/TrEMBL Mapped Features Mapped Features have been reorganized, please
see this article for details. Additional mapped features and mutations can
be found on GBrowse or related reports. External Data Linkouts Crossreferences Expression Data Transcript ExpressionComment: maternally deposited
Comment: reported as atrium primordium
Additional Descriptive Data
Marker for Subcellular Localization CV Term Polypeptide Expression
Additional Descriptive Data
Marker for Subcellular Localization (GO Cellular Component) Expression Deduced from Reporters
High-Throughput Expression Data
Associated Tools
Reference
FlyAtlas Anatomy Microarray
Linear, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
535.325
Larval Midgut
157.5
Larval Hindgut
795.1
Larval Malpighian Tubules
651.2
Larval Fat Body
648.5
Larval Salivary Gland
1037.4
Larval Trachea
555.325
Larval Carcass
655.65
Adult Head
422.8
Adult Eye
314.875
Adult Brain
222
Adult Thoracic-Abdominal Ganglion
272.7
Adult Crop
485.7
Adult Midgut
217.9
Adult Hindgut
489.7
Adult Malpighian Tubules
368.8
Adult Fat Body
416.4
Adult Salivary Gland
1453.5
Adult Heart
242.15
Adult VirginFemale Spermatheca
397.6
Adult InseminatedFemale Spermatheca
426.2
Adult Ovary
251.3
Adult Testis
96.9
Adult Male Accessory Gland
1691.1
Adult Carcass
295.9
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
535.325
Larval Midgut
157.5
Larval Hindgut
(795.1)
Larval Malpighian Tubules
(651.2)
Larval Fat Body
(648.5)
Larval Salivary Gland
(1037.4)
Larval Trachea
(555.325)
Larval Carcass
(655.65)
Adult Head
422.8
Adult Eye
314.875
Adult Brain
222
Adult Thoracic-Abdominal Ganglion
272.7
Adult Crop
485.7
Adult Midgut
217.9
Adult Hindgut
489.7
Adult Malpighian Tubules
368.8
Adult Fat Body
416.4
Adult Salivary Gland
(1453.5)
Adult Heart
242.15
Adult VirginFemale Spermatheca
397.6
Adult InseminatedFemale Spermatheca
426.2
Adult Ovary
251.3
Adult Testis
96.9
Adult Male Accessory Gland
(1691.1)
Adult Carcass
295.9
Expression Level Scale
None
Low
Moderate
High
Linear, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
535.325
Larval Midgut
157.5
Larval Hindgut
795.1
Larval Malpighian Tubules
651.2
Larval Fat Body
648.5
Larval Salivary Gland
1037.4
Larval Trachea
555.325
Larval Carcass
655.65
Adult Head
422.8
Adult Eye
314.875
Adult Brain
222
Adult Thoracic-Abdominal Ganglion
272.7
Adult Crop
485.7
Adult Midgut
217.9
Adult Hindgut
489.7
Adult Malpighian Tubules
368.8
Adult Fat Body
416.4
Adult Salivary Gland
(1453.5)
Adult Heart
242.15
Adult VirginFemale Spermatheca
397.6
Adult InseminatedFemale Spermatheca
426.2
Adult Ovary
251.3
Adult Testis
96.9
Adult Male Accessory Gland
(1691.1)
Adult Carcass
295.9
Expression Level Scale
None
Low
Moderate
High
Very high
Linear, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
535.325
Larval Midgut
157.5
Larval Hindgut
795.1
Larval Malpighian Tubules
651.2
Larval Fat Body
648.5
Larval Salivary Gland
1037.4
Larval Trachea
555.325
Larval Carcass
655.65
Adult Head
422.8
Adult Eye
314.875
Adult Brain
222
Adult Thoracic-Abdominal Ganglion
272.7
Adult Crop
485.7
Adult Midgut
217.9
Adult Hindgut
489.7
Adult Malpighian Tubules
368.8
Adult Fat Body
416.4
Adult Salivary Gland
1453.5
Adult Heart
242.15
Adult VirginFemale Spermatheca
397.6
Adult InseminatedFemale Spermatheca
426.2
Adult Ovary
251.3
Adult Testis
96.9
Adult Male Accessory Gland
1691.1
Adult Carcass
295.9
Expression Level Scale
Very high
log, scaled to maximum expression level
Tissue
Expression Level
Larval Central Nervous System
535.325
Larval Midgut
157.5
Larval Hindgut
795.1
Larval Malpighian Tubules
651.2
Larval Fat Body
648.5
Larval Salivary Gland
1037.4
Larval Trachea
555.325
Larval Carcass
655.65
Adult Head
422.8
Adult Eye
314.875
Adult Brain
222
Adult Thoracic-Abdominal Ganglion
272.7
Adult Crop
485.7
Adult Midgut
217.9
Adult Hindgut
489.7
Adult Malpighian Tubules
368.8
Adult Fat Body
416.4
Adult Salivary Gland
1453.5
Adult Heart
242.15
Adult VirginFemale Spermatheca
397.6
Adult InseminatedFemale Spermatheca
426.2
Adult Ovary
251.3
Adult Testis
96.9
Adult Male Accessory Gland
1691.1
Adult Carcass
295.9
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
Larval Central Nervous System
535.325
Larval Midgut
157.5
Larval Hindgut
795.1
Larval Malpighian Tubules
651.2
Larval Fat Body
648.5
Larval Salivary Gland
(1037.4)
Larval Trachea
555.325
Larval Carcass
655.65
Adult Head
422.8
Adult Eye
314.875
Adult Brain
222
Adult Thoracic-Abdominal Ganglion
272.7
Adult Crop
485.7
Adult Midgut
217.9
Adult Hindgut
489.7
Adult Malpighian Tubules
368.8
Adult Fat Body
416.4
Adult Salivary Gland
(1453.5)
Adult Heart
242.15
Adult VirginFemale Spermatheca
397.6
Adult InseminatedFemale Spermatheca
426.2
Adult Ovary
251.3
Adult Testis
96.9
Adult Male Accessory Gland
(1691.1)
Adult Carcass
295.9
Expression Level Scale
None
Low
Moderate
High
log, scaled to High level expression
Tissue
Expression Level
Larval Central Nervous System
535.325
Larval Midgut
157.5
Larval Hindgut
795.1
Larval Malpighian Tubules
651.2
Larval Fat Body
648.5
Larval Salivary Gland
1037.4
Larval Trachea
555.325
Larval Carcass
655.65
Adult Head
422.8
Adult Eye
314.875
Adult Brain
222
Adult Thoracic-Abdominal Ganglion
272.7
Adult Crop
485.7
Adult Midgut
217.9
Adult Hindgut
489.7
Adult Malpighian Tubules
368.8
Adult Fat Body
416.4
Adult Salivary Gland
1453.5
Adult Heart
242.15
Adult VirginFemale Spermatheca
397.6
Adult InseminatedFemale Spermatheca
426.2
Adult Ovary
251.3
Adult Testis
96.9
Adult Male Accessory Gland
1691.1
Adult Carcass
295.9
Expression Level Scale
None
Low
Moderate
High
Very high
log, scaled to Very high expression
Tissue
Expression Level
Larval Central Nervous System
535.325
Larval Midgut
157.5
Larval Hindgut
795.1
Larval Malpighian Tubules
651.2
Larval Fat Body
648.5
Larval Salivary Gland
1037.4
Larval Trachea
555.325
Larval Carcass
655.65
Adult Head
422.8
Adult Eye
314.875
Adult Brain
222
Adult Thoracic-Abdominal Ganglion
272.7
Adult Crop
485.7
Adult Midgut
217.9
Adult Hindgut
489.7
Adult Malpighian Tubules
368.8
Adult Fat Body
416.4
Adult Salivary Gland
1453.5
Adult Heart
242.15
Adult VirginFemale Spermatheca
397.6
Adult InseminatedFemale Spermatheca
426.2
Adult Ovary
251.3
Adult Testis
96.9
Adult Male Accessory Gland
1691.1
Adult Carcass
295.9
Expression Level Scale
None
Low
Moderate
High
Very high
Heatmap
Tissue
Expression Level
Larval Central Nervous System
Larval Midgut
Larval Hindgut
Larval Malpighian Tubules
Larval Fat Body
Larval Salivary Gland
Larval Trachea
Larval Carcass
Adult Head
Adult Eye
Adult Brain
Adult Thoracic-Abdominal Ganglion
Adult Crop
Adult Midgut
Adult Hindgut
Adult Malpighian Tubules
Adult Fat Body
Adult Salivary Gland
Adult Heart
Adult VirginFemale Spermatheca
Adult InseminatedFemale Spermatheca
Adult Ovary
Adult Testis
Adult Male Accessory Gland
Adult Carcass
FlyAtlas Organ/Tissue Expression, larval vs. adult
Larval Expression Level
Tissue
Adult Expression Level
NA
Head
422.8
NA
Eye
314.875
NA
Brain
222
535.325
Central Nervous System
NA
NA
Thoracic-Abdominal Ganglion
272.7
NA
Crop
485.7
157.5
Midgut
217.9
795.1
Hindgut
489.7
651.2
Malpighian Tubules
368.8
648.5
Fat Body
416.4
1037.4
Salivary Gland
1453.5
NA
Heart
242.15
555.325
Trachea
NA
NA
VirginFemale Spermatheca
397.6
NA
InseminatedFemale Spermatheca
426.2
NA
Ovary
251.3
NA
Testis
96.9
NA
Male Accessory Gland
1691.1
655.65
Carcass
295.9
modENCODE Anatomy RNA-Seq
Linear, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
35
central nervous system, larvae L3
35
central nervous system, pupae P8
15
head, virgin 1-day female
22
head, virgin 4-day female
18
head, virgin 20-day female
21
head, mated 1-day female
21
head, mated 4-day female
18
head, mated 20-day female
19
head, mated 1-day male
18
head, mated 4-day male
23
head, mated 20-day male
31
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
88
digestive system, larvae L3 wandering
20
digestive system, 1-day adult
13
digestive system, 4-day adult
14
digestive system, 20-day adult
18
fat body, larvae L3 wandering
22
fat body, white prepupae
29
fat body, pupae P8
66
carcass, larvae L3 wandering
32
carcass, 1-day adult
19
carcass, 4-day adult
19
carcass, 20-day adult
23
ovary, virgin 4-day female
10
ovary, mated 4-day female
12
testis, mated 4-day male
25
accessory gland, mated 4-day male
78
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Linear, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(35)
central nervous system, larvae L3
(35)
central nervous system, pupae P8
15
head, virgin 1-day female
22
head, virgin 4-day female
18
head, virgin 20-day female
21
head, mated 1-day female
21
head, mated 4-day female
18
head, mated 20-day female
19
head, mated 1-day male
18
head, mated 4-day male
23
head, mated 20-day male
(31)
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
(88)
digestive system, larvae L3 wandering
20
digestive system, 1-day adult
13
digestive system, 4-day adult
14
digestive system, 20-day adult
18
fat body, larvae L3 wandering
22
fat body, white prepupae
(29)
fat body, pupae P8
(66)
carcass, larvae L3 wandering
(32)
carcass, 1-day adult
19
carcass, 4-day adult
19
carcass, 20-day adult
23
ovary, virgin 4-day female
10
ovary, mated 4-day female
12
testis, mated 4-day male
25
accessory gland, mated 4-day male
(78)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
35
central nervous system, larvae L3
35
central nervous system, pupae P8
15
head, virgin 1-day female
22
head, virgin 4-day female
18
head, virgin 20-day female
21
head, mated 1-day female
21
head, mated 4-day female
18
head, mated 20-day female
19
head, mated 1-day male
18
head, mated 4-day male
23
head, mated 20-day male
31
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
88
digestive system, larvae L3 wandering
20
digestive system, 1-day adult
13
digestive system, 4-day adult
14
digestive system, 20-day adult
18
fat body, larvae L3 wandering
22
fat body, white prepupae
29
fat body, pupae P8
66
carcass, larvae L3 wandering
32
carcass, 1-day adult
19
carcass, 4-day adult
19
carcass, 20-day adult
23
ovary, virgin 4-day female
10
ovary, mated 4-day female
12
testis, mated 4-day male
25
accessory gland, mated 4-day male
78
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
35
central nervous system, larvae L3
35
central nervous system, pupae P8
15
head, virgin 1-day female
22
head, virgin 4-day female
18
head, virgin 20-day female
21
head, mated 1-day female
21
head, mated 4-day female
18
head, mated 20-day female
19
head, mated 1-day male
18
head, mated 4-day male
23
head, mated 20-day male
31
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
88
digestive system, larvae L3 wandering
20
digestive system, 1-day adult
13
digestive system, 4-day adult
14
digestive system, 20-day adult
18
fat body, larvae L3 wandering
22
fat body, white prepupae
29
fat body, pupae P8
66
carcass, larvae L3 wandering
32
carcass, 1-day adult
19
carcass, 4-day adult
19
carcass, 20-day adult
23
ovary, virgin 4-day female
10
ovary, mated 4-day female
12
testis, mated 4-day male
25
accessory gland, mated 4-day male
78
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Tissue
Expression Level
imaginal disc, larvae L3 wandering
35
central nervous system, larvae L3
35
central nervous system, pupae P8
15
head, virgin 1-day female
22
head, virgin 4-day female
18
head, virgin 20-day female
21
head, mated 1-day female
21
head, mated 4-day female
18
head, mated 20-day female
19
head, mated 1-day male
18
head, mated 4-day male
23
head, mated 20-day male
31
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
88
digestive system, larvae L3 wandering
20
digestive system, 1-day adult
13
digestive system, 4-day adult
14
digestive system, 20-day adult
18
fat body, larvae L3 wandering
22
fat body, white prepupae
29
fat body, pupae P8
66
carcass, larvae L3 wandering
32
carcass, 1-day adult
19
carcass, 4-day adult
19
carcass, 20-day adult
23
ovary, virgin 4-day female
10
ovary, mated 4-day female
12
testis, mated 4-day male
25
accessory gland, mated 4-day male
78
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
(35)
central nervous system, larvae L3
(35)
central nervous system, pupae P8
15
head, virgin 1-day female
22
head, virgin 4-day female
18
head, virgin 20-day female
21
head, mated 1-day female
21
head, mated 4-day female
18
head, mated 20-day female
19
head, mated 1-day male
18
head, mated 4-day male
23
head, mated 20-day male
31
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
(88)
digestive system, larvae L3 wandering
20
digestive system, 1-day adult
13
digestive system, 4-day adult
14
digestive system, 20-day adult
18
fat body, larvae L3 wandering
22
fat body, white prepupae
29
fat body, pupae P8
(66)
carcass, larvae L3 wandering
32
carcass, 1-day adult
19
carcass, 4-day adult
19
carcass, 20-day adult
23
ovary, virgin 4-day female
10
ovary, mated 4-day female
12
testis, mated 4-day male
25
accessory gland, mated 4-day male
(78)
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
35
central nervous system, larvae L3
35
central nervous system, pupae P8
15
head, virgin 1-day female
22
head, virgin 4-day female
18
head, virgin 20-day female
21
head, mated 1-day female
21
head, mated 4-day female
18
head, mated 20-day female
19
head, mated 1-day male
18
head, mated 4-day male
23
head, mated 20-day male
31
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
88
digestive system, larvae L3 wandering
20
digestive system, 1-day adult
13
digestive system, 4-day adult
14
digestive system, 20-day adult
18
fat body, larvae L3 wandering
22
fat body, white prepupae
29
fat body, pupae P8
66
carcass, larvae L3 wandering
32
carcass, 1-day adult
19
carcass, 4-day adult
19
carcass, 20-day adult
23
ovary, virgin 4-day female
10
ovary, mated 4-day female
12
testis, mated 4-day male
25
accessory gland, mated 4-day male
78
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Tissue
Expression Level
imaginal disc, larvae L3 wandering
35
central nervous system, larvae L3
35
central nervous system, pupae P8
15
head, virgin 1-day female
22
head, virgin 4-day female
18
head, virgin 20-day female
21
head, mated 1-day female
21
head, mated 4-day female
18
head, mated 20-day female
19
head, mated 1-day male
18
head, mated 4-day male
23
head, mated 20-day male
31
salivary gland, larvae L3 wandering
7
salivary gland, white prepupae
88
digestive system, larvae L3 wandering
20
digestive system, 1-day adult
13
digestive system, 4-day adult
14
digestive system, 20-day adult
18
fat body, larvae L3 wandering
22
fat body, white prepupae
29
fat body, pupae P8
66
carcass, larvae L3 wandering
32
carcass, 1-day adult
19
carcass, 4-day adult
19
carcass, 20-day adult
23
ovary, virgin 4-day female
10
ovary, mated 4-day female
12
testis, mated 4-day male
25
accessory gland, mated 4-day male
78
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Tissue
Expression Level
imaginal disc, larvae L3 wandering
central nervous system, larvae L3
central nervous system, pupae P8
head, virgin 1-day female
head, virgin 4-day female
head, virgin 20-day female
head, mated 1-day female
head, mated 4-day female
head, mated 20-day female
head, mated 1-day male
head, mated 4-day male
head, mated 20-day male
salivary gland, larvae L3 wandering
salivary gland, white prepupae
digestive system, larvae L3 wandering
digestive system, 1-day adult
digestive system, 4-day adult
digestive system, 20-day adult
fat body, larvae L3 wandering
fat body, white prepupae
fat body, pupae P8
carcass, larvae L3 wandering
carcass, 1-day adult
carcass, 4-day adult
carcass, 20-day adult
ovary, virgin 4-day female
ovary, mated 4-day female
testis, mated 4-day male
accessory gland, mated 4-day male
modENCODE Development RNA-Seq
Linear, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
18
embryo 02-04hr
22
embryo 04-06hr
28
embryo 06-08hr
53
embryo 08-10hr
66
embryo 10-12hr
76
embryo 12-14hr
60
embryo 14-16hr
64
embryo 16-18hr
66
embryo 18-20hr
69
embryo 20-22hr
52
embryo 22-24hr
53
larva L1
61
larva L2
56
larva L3 12hr old
42
larva L3 puffstage 1-2
31
larva L3 puffstage 3-6
37
larva L3 puffstage 7-9
40
white prepupae new
45
white prepupae 12hr
97
white prepupae 24hr
60
pupae 2d postWPP
46
pupae 3d postWPP
33
pupae 4d postWPP
23
adult male 01day
20
adult male 05day
23
adult male 30day
28
adult female 01day
23
adult female 05day
17
adult female 30day
20
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
18
embryo 02-04hr
22
embryo 04-06hr
(28)
embryo 06-08hr
(53)
embryo 08-10hr
(66)
embryo 10-12hr
(76)
embryo 12-14hr
(60)
embryo 14-16hr
(64)
embryo 16-18hr
(66)
embryo 18-20hr
(69)
embryo 20-22hr
(52)
embryo 22-24hr
(53)
larva L1
(61)
larva L2
(56)
larva L3 12hr old
(42)
larva L3 puffstage 1-2
(31)
larva L3 puffstage 3-6
(37)
larva L3 puffstage 7-9
(40)
white prepupae new
(45)
white prepupae 12hr
(97)
white prepupae 24hr
(60)
pupae 2d postWPP
(46)
pupae 3d postWPP
(33)
pupae 4d postWPP
23
adult male 01day
20
adult male 05day
23
adult male 30day
(28)
adult female 01day
23
adult female 05day
17
adult female 30day
20
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
18
embryo 02-04hr
22
embryo 04-06hr
28
embryo 06-08hr
53
embryo 08-10hr
66
embryo 10-12hr
76
embryo 12-14hr
60
embryo 14-16hr
64
embryo 16-18hr
66
embryo 18-20hr
69
embryo 20-22hr
52
embryo 22-24hr
53
larva L1
61
larva L2
56
larva L3 12hr old
42
larva L3 puffstage 1-2
31
larva L3 puffstage 3-6
37
larva L3 puffstage 7-9
40
white prepupae new
45
white prepupae 12hr
97
white prepupae 24hr
60
pupae 2d postWPP
46
pupae 3d postWPP
33
pupae 4d postWPP
23
adult male 01day
20
adult male 05day
23
adult male 30day
28
adult female 01day
23
adult female 05day
17
adult female 30day
20
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
18
embryo 02-04hr
22
embryo 04-06hr
28
embryo 06-08hr
53
embryo 08-10hr
66
embryo 10-12hr
76
embryo 12-14hr
60
embryo 14-16hr
64
embryo 16-18hr
66
embryo 18-20hr
69
embryo 20-22hr
52
embryo 22-24hr
53
larva L1
61
larva L2
56
larva L3 12hr old
42
larva L3 puffstage 1-2
31
larva L3 puffstage 3-6
37
larva L3 puffstage 7-9
40
white prepupae new
45
white prepupae 12hr
97
white prepupae 24hr
60
pupae 2d postWPP
46
pupae 3d postWPP
33
pupae 4d postWPP
23
adult male 01day
20
adult male 05day
23
adult male 30day
28
adult female 01day
23
adult female 05day
17
adult female 30day
20
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Developmental Stage
Expression Level
embryo 00-02hr
18
embryo 02-04hr
22
embryo 04-06hr
28
embryo 06-08hr
53
embryo 08-10hr
66
embryo 10-12hr
76
embryo 12-14hr
60
embryo 14-16hr
64
embryo 16-18hr
66
embryo 18-20hr
69
embryo 20-22hr
52
embryo 22-24hr
53
larva L1
61
larva L2
56
larva L3 12hr old
42
larva L3 puffstage 1-2
31
larva L3 puffstage 3-6
37
larva L3 puffstage 7-9
40
white prepupae new
45
white prepupae 12hr
97
white prepupae 24hr
60
pupae 2d postWPP
46
pupae 3d postWPP
33
pupae 4d postWPP
23
adult male 01day
20
adult male 05day
23
adult male 30day
28
adult female 01day
23
adult female 05day
17
adult female 30day
20
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Developmental Stage
Expression Level
embryo 00-02hr
18
embryo 02-04hr
22
embryo 04-06hr
28
embryo 06-08hr
(53)
embryo 08-10hr
(66)
embryo 10-12hr
(76)
embryo 12-14hr
(60)
embryo 14-16hr
(64)
embryo 16-18hr
(66)
embryo 18-20hr
(69)
embryo 20-22hr
(52)
embryo 22-24hr
(53)
larva L1
(61)
larva L2
(56)
larva L3 12hr old
(42)
larva L3 puffstage 1-2
31
larva L3 puffstage 3-6
(37)
larva L3 puffstage 7-9
(40)
white prepupae new
(45)
white prepupae 12hr
(97)
white prepupae 24hr
(60)
pupae 2d postWPP
(46)
pupae 3d postWPP
(33)
pupae 4d postWPP
23
adult male 01day
20
adult male 05day
23
adult male 30day
28
adult female 01day
23
adult female 05day
17
adult female 30day
20
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Developmental Stage
Expression Level
embryo 00-02hr
18
embryo 02-04hr
22
embryo 04-06hr
28
embryo 06-08hr
53
embryo 08-10hr
66
embryo 10-12hr
76
embryo 12-14hr
60
embryo 14-16hr
64
embryo 16-18hr
66
embryo 18-20hr
69
embryo 20-22hr
52
embryo 22-24hr
53
larva L1
61
larva L2
56
larva L3 12hr old
42
larva L3 puffstage 1-2
31
larva L3 puffstage 3-6
37
larva L3 puffstage 7-9
40
white prepupae new
45
white prepupae 12hr
97
white prepupae 24hr
60
pupae 2d postWPP
46
pupae 3d postWPP
33
pupae 4d postWPP
23
adult male 01day
20
adult male 05day
23
adult male 30day
28
adult female 01day
23
adult female 05day
17
adult female 30day
20
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Developmental Stage
Expression Level
embryo 00-02hr
18
embryo 02-04hr
22
embryo 04-06hr
28
embryo 06-08hr
53
embryo 08-10hr
66
embryo 10-12hr
76
embryo 12-14hr
60
embryo 14-16hr
64
embryo 16-18hr
66
embryo 18-20hr
69
embryo 20-22hr
52
embryo 22-24hr
53
larva L1
61
larva L2
56
larva L3 12hr old
42
larva L3 puffstage 1-2
31
larva L3 puffstage 3-6
37
larva L3 puffstage 7-9
40
white prepupae new
45
white prepupae 12hr
97
white prepupae 24hr
60
pupae 2d postWPP
46
pupae 3d postWPP
33
pupae 4d postWPP
23
adult male 01day
20
adult male 05day
23
adult male 30day
28
adult female 01day
23
adult female 05day
17
adult female 30day
20
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Developmental Stage
Expression Level
embryo 00-02hr
embryo 02-04hr
embryo 04-06hr
embryo 06-08hr
embryo 08-10hr
embryo 10-12hr
embryo 12-14hr
embryo 14-16hr
embryo 16-18hr
embryo 18-20hr
embryo 20-22hr
embryo 22-24hr
larva L1
larva L2
larva L3 12hr old
larva L3 puffstage 1-2
larva L3 puffstage 3-6
larva L3 puffstage 7-9
white prepupae new
white prepupae 12hr
white prepupae 24hr
pupae 2d postWPP
pupae 3d postWPP
pupae 4d postWPP
adult male 01day
adult male 05day
adult male 30day
adult female 01day
adult female 05day
adult female 30day
modENCODE Cell Lines RNA-Seq
Linear, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
125
Schneider line 2 Sg4
135
embryonic 1182-4H
222
embryonic GM2
320
embryonic Kc167
278
embryonic S1
125
embryonic S3
126
leg disc CME L1
210
wing disc CME-W2
216
wing disc ML-DmD8
211
wing disc ML-DmD9
216
wing disc ML-DmD16-c3
250
wing disc ML-DmD21
103
wing disc ML-DmD32
262
haltere disc ML-DmD17-c3
82
eye-antennal disc ML-DmD11
219
antennal disc ML-DmD20-c5
157
mixed discs ML-DmD4-c1
192
CNS ML-DmBG1-c1
155
CNS ML-DmBG2-c2
48
tumorous blood cells mbn2
45
ovary fGS/OSS
107
ovary OSC
89
ovary OSS
32
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(125)
Schneider line 2 Sg4
(135)
embryonic 1182-4H
(222)
embryonic GM2
(320)
embryonic Kc167
(278)
embryonic S1
(125)
embryonic S3
(126)
leg disc CME L1
(210)
wing disc CME-W2
(216)
wing disc ML-DmD8
(211)
wing disc ML-DmD9
(216)
wing disc ML-DmD16-c3
(250)
wing disc ML-DmD21
(103)
wing disc ML-DmD32
(262)
haltere disc ML-DmD17-c3
(82)
eye-antennal disc ML-DmD11
(219)
antennal disc ML-DmD20-c5
(157)
mixed discs ML-DmD4-c1
(192)
CNS ML-DmBG1-c1
(155)
CNS ML-DmBG2-c2
(48)
tumorous blood cells mbn2
(45)
ovary fGS/OSS
(107)
ovary OSC
(89)
ovary OSS
(32)
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
(125)
Schneider line 2 Sg4
(135)
embryonic 1182-4H
(222)
embryonic GM2
(320)
embryonic Kc167
(278)
embryonic S1
(125)
embryonic S3
(126)
leg disc CME L1
(210)
wing disc CME-W2
(216)
wing disc ML-DmD8
(211)
wing disc ML-DmD9
(216)
wing disc ML-DmD16-c3
(250)
wing disc ML-DmD21
103
wing disc ML-DmD32
(262)
haltere disc ML-DmD17-c3
82
eye-antennal disc ML-DmD11
(219)
antennal disc ML-DmD20-c5
(157)
mixed discs ML-DmD4-c1
(192)
CNS ML-DmBG1-c1
(155)
CNS ML-DmBG2-c2
48
tumorous blood cells mbn2
45
ovary fGS/OSS
107
ovary OSC
89
ovary OSS
32
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
125
Schneider line 2 Sg4
135
embryonic 1182-4H
222
embryonic GM2
320
embryonic Kc167
278
embryonic S1
125
embryonic S3
126
leg disc CME L1
210
wing disc CME-W2
216
wing disc ML-DmD8
211
wing disc ML-DmD9
216
wing disc ML-DmD16-c3
250
wing disc ML-DmD21
103
wing disc ML-DmD32
262
haltere disc ML-DmD17-c3
82
eye-antennal disc ML-DmD11
219
antennal disc ML-DmD20-c5
157
mixed discs ML-DmD4-c1
192
CNS ML-DmBG1-c1
155
CNS ML-DmBG2-c2
48
tumorous blood cells mbn2
45
ovary fGS/OSS
107
ovary OSC
89
ovary OSS
32
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Cell Line
Expression Level
Schneider line 2 S2R+
125
Schneider line 2 Sg4
135
embryonic 1182-4H
222
embryonic GM2
320
embryonic Kc167
278
embryonic S1
125
embryonic S3
126
leg disc CME L1
210
wing disc CME-W2
216
wing disc ML-DmD8
211
wing disc ML-DmD9
216
wing disc ML-DmD16-c3
250
wing disc ML-DmD21
103
wing disc ML-DmD32
262
haltere disc ML-DmD17-c3
82
eye-antennal disc ML-DmD11
219
antennal disc ML-DmD20-c5
157
mixed discs ML-DmD4-c1
192
CNS ML-DmBG1-c1
155
CNS ML-DmBG2-c2
48
tumorous blood cells mbn2
45
ovary fGS/OSS
107
ovary OSC
89
ovary OSS
32
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Moderate expression
Cell Line
Expression Level
Schneider line 2 S2R+
(125)
Schneider line 2 Sg4
(135)
embryonic 1182-4H
(222)
embryonic GM2
(320)
embryonic Kc167
(278)
embryonic S1
(125)
embryonic S3
(126)
leg disc CME L1
(210)
wing disc CME-W2
(216)
wing disc ML-DmD8
(211)
wing disc ML-DmD9
(216)
wing disc ML-DmD16-c3
(250)
wing disc ML-DmD21
(103)
wing disc ML-DmD32
(262)
haltere disc ML-DmD17-c3
(82)
eye-antennal disc ML-DmD11
(219)
antennal disc ML-DmD20-c5
(157)
mixed discs ML-DmD4-c1
(192)
CNS ML-DmBG1-c1
(155)
CNS ML-DmBG2-c2
(48)
tumorous blood cells mbn2
(45)
ovary fGS/OSS
(107)
ovary OSC
(89)
ovary OSS
32
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Cell Line
Expression Level
Schneider line 2 S2R+
125
Schneider line 2 Sg4
135
embryonic 1182-4H
(222)
embryonic GM2
(320)
embryonic Kc167
(278)
embryonic S1
125
embryonic S3
126
leg disc CME L1
(210)
wing disc CME-W2
(216)
wing disc ML-DmD8
(211)
wing disc ML-DmD9
(216)
wing disc ML-DmD16-c3
(250)
wing disc ML-DmD21
103
wing disc ML-DmD32
(262)
haltere disc ML-DmD17-c3
82
eye-antennal disc ML-DmD11
(219)
antennal disc ML-DmD20-c5
(157)
mixed discs ML-DmD4-c1
(192)
CNS ML-DmBG1-c1
(155)
CNS ML-DmBG2-c2
48
tumorous blood cells mbn2
45
ovary fGS/OSS
107
ovary OSC
89
ovary OSS
32
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Cell Line
Expression Level
Schneider line 2 S2R+
125
Schneider line 2 Sg4
135
embryonic 1182-4H
222
embryonic GM2
320
embryonic Kc167
278
embryonic S1
125
embryonic S3
126
leg disc CME L1
210
wing disc CME-W2
216
wing disc ML-DmD8
211
wing disc ML-DmD9
216
wing disc ML-DmD16-c3
250
wing disc ML-DmD21
103
wing disc ML-DmD32
262
haltere disc ML-DmD17-c3
82
eye-antennal disc ML-DmD11
219
antennal disc ML-DmD20-c5
157
mixed discs ML-DmD4-c1
192
CNS ML-DmBG1-c1
155
CNS ML-DmBG2-c2
48
tumorous blood cells mbn2
45
ovary fGS/OSS
107
ovary OSC
89
ovary OSS
32
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Cell Line
Expression Level
Schneider line 2 S2R+
Schneider line 2 Sg4
embryonic 1182-4H
embryonic GM2
embryonic Kc167
embryonic S1
embryonic S3
leg disc CME L1
wing disc CME-W2
wing disc ML-DmD8
wing disc ML-DmD9
wing disc ML-DmD16-c3
wing disc ML-DmD21
wing disc ML-DmD32
haltere disc ML-DmD17-c3
eye-antennal disc ML-DmD11
antennal disc ML-DmD20-c5
mixed discs ML-DmD4-c1
CNS ML-DmBG1-c1
CNS ML-DmBG2-c2
tumorous blood cells mbn2
ovary fGS/OSS
ovary OSC
ovary OSS
modENCODE Treatments RNA-Seq
Linear, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
22
cold shock, 4-day adult
18
heat shock, 4-day adult
22
Cadmium 50 mM 6 hrs, larvae L3
25
Cadmium 50 mM 12 hrs, larvae L3
30
Cadmium 50 mM 48 hrs, 4-day adult
30
Cadmium 100 mM 48 hrs, 4-day adult
42
Copper 0.5 mM 12 hrs, larvae L3
21
Copper 15 mM 48 hrs, 4-day adult
26
Zinc 5 mM 12 hrs, larvae L3
26
Zinc 4.5 mM 48 hrs, 4-day adult
29
Ethanol 2.5% 3 hrs, larvae L3
23
Ethanol 5% 3 hrs, larvae L3
28
Ethanol 10% 3 hrs, larvae L3
29
Caffeine 1.5 mg/ml 4 hrs, larvae L3
25
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
22
Caffeine 25 mg/ml 48 hrs, 4-day adult
18
Paraquat 5 mM 48 hrs, 4-day adult
18
Paraquat 10 mM 48 hrs, 4-day adult
30
Rotenone 2 μg 12 hrs, larvae L3
32
Rotenone 8 μg 12 hrs, larvae L3
26
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
22
cold shock, 4-day adult
18
heat shock, 4-day adult
22
Cadmium 50 mM 6 hrs, larvae L3
25
Cadmium 50 mM 12 hrs, larvae L3
(30)
Cadmium 50 mM 48 hrs, 4-day adult
(30)
Cadmium 100 mM 48 hrs, 4-day adult
(42)
Copper 0.5 mM 12 hrs, larvae L3
21
Copper 15 mM 48 hrs, 4-day adult
26
Zinc 5 mM 12 hrs, larvae L3
26
Zinc 4.5 mM 48 hrs, 4-day adult
(29)
Ethanol 2.5% 3 hrs, larvae L3
23
Ethanol 5% 3 hrs, larvae L3
(28)
Ethanol 10% 3 hrs, larvae L3
(29)
Caffeine 1.5 mg/ml 4 hrs, larvae L3
25
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
22
Caffeine 25 mg/ml 48 hrs, 4-day adult
18
Paraquat 5 mM 48 hrs, 4-day adult
18
Paraquat 10 mM 48 hrs, 4-day adult
(30)
Rotenone 2 μg 12 hrs, larvae L3
(32)
Rotenone 8 μg 12 hrs, larvae L3
26
Expression Level Scale
Very low
Low
Moderate
Moderately high
Linear, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
22
cold shock, 4-day adult
18
heat shock, 4-day adult
22
Cadmium 50 mM 6 hrs, larvae L3
25
Cadmium 50 mM 12 hrs, larvae L3
30
Cadmium 50 mM 48 hrs, 4-day adult
30
Cadmium 100 mM 48 hrs, 4-day adult
42
Copper 0.5 mM 12 hrs, larvae L3
21
Copper 15 mM 48 hrs, 4-day adult
26
Zinc 5 mM 12 hrs, larvae L3
26
Zinc 4.5 mM 48 hrs, 4-day adult
29
Ethanol 2.5% 3 hrs, larvae L3
23
Ethanol 5% 3 hrs, larvae L3
28
Ethanol 10% 3 hrs, larvae L3
29
Caffeine 1.5 mg/ml 4 hrs, larvae L3
25
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
22
Caffeine 25 mg/ml 48 hrs, 4-day adult
18
Paraquat 5 mM 48 hrs, 4-day adult
18
Paraquat 10 mM 48 hrs, 4-day adult
30
Rotenone 2 μg 12 hrs, larvae L3
32
Rotenone 8 μg 12 hrs, larvae L3
26
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Linear, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
22
cold shock, 4-day adult
18
heat shock, 4-day adult
22
Cadmium 50 mM 6 hrs, larvae L3
25
Cadmium 50 mM 12 hrs, larvae L3
30
Cadmium 50 mM 48 hrs, 4-day adult
30
Cadmium 100 mM 48 hrs, 4-day adult
42
Copper 0.5 mM 12 hrs, larvae L3
21
Copper 15 mM 48 hrs, 4-day adult
26
Zinc 5 mM 12 hrs, larvae L3
26
Zinc 4.5 mM 48 hrs, 4-day adult
29
Ethanol 2.5% 3 hrs, larvae L3
23
Ethanol 5% 3 hrs, larvae L3
28
Ethanol 10% 3 hrs, larvae L3
29
Caffeine 1.5 mg/ml 4 hrs, larvae L3
25
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
22
Caffeine 25 mg/ml 48 hrs, 4-day adult
18
Paraquat 5 mM 48 hrs, 4-day adult
18
Paraquat 10 mM 48 hrs, 4-day adult
30
Rotenone 2 μg 12 hrs, larvae L3
32
Rotenone 8 μg 12 hrs, larvae L3
26
Expression Level Scale
Extremely high
log, scaled to maximum expression level
Treatment
Expression Level
extended cold, 4-day adult
22
cold shock, 4-day adult
18
heat shock, 4-day adult
22
Cadmium 50 mM 6 hrs, larvae L3
25
Cadmium 50 mM 12 hrs, larvae L3
30
Cadmium 50 mM 48 hrs, 4-day adult
30
Cadmium 100 mM 48 hrs, 4-day adult
42
Copper 0.5 mM 12 hrs, larvae L3
21
Copper 15 mM 48 hrs, 4-day adult
26
Zinc 5 mM 12 hrs, larvae L3
26
Zinc 4.5 mM 48 hrs, 4-day adult
29
Ethanol 2.5% 3 hrs, larvae L3
23
Ethanol 5% 3 hrs, larvae L3
28
Ethanol 10% 3 hrs, larvae L3
29
Caffeine 1.5 mg/ml 4 hrs, larvae L3
25
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
22
Caffeine 25 mg/ml 48 hrs, 4-day adult
18
Paraquat 5 mM 48 hrs, 4-day adult
18
Paraquat 10 mM 48 hrs, 4-day adult
30
Rotenone 2 μg 12 hrs, larvae L3
32
Rotenone 8 μg 12 hrs, larvae L3
26
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
log, scaled to Moderate expression
Treatment
Expression Level
extended cold, 4-day adult
22
cold shock, 4-day adult
18
heat shock, 4-day adult
22
Cadmium 50 mM 6 hrs, larvae L3
25
Cadmium 50 mM 12 hrs, larvae L3
30
Cadmium 50 mM 48 hrs, 4-day adult
30
Cadmium 100 mM 48 hrs, 4-day adult
(42)
Copper 0.5 mM 12 hrs, larvae L3
21
Copper 15 mM 48 hrs, 4-day adult
26
Zinc 5 mM 12 hrs, larvae L3
26
Zinc 4.5 mM 48 hrs, 4-day adult
29
Ethanol 2.5% 3 hrs, larvae L3
23
Ethanol 5% 3 hrs, larvae L3
28
Ethanol 10% 3 hrs, larvae L3
29
Caffeine 1.5 mg/ml 4 hrs, larvae L3
25
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
22
Caffeine 25 mg/ml 48 hrs, 4-day adult
18
Paraquat 5 mM 48 hrs, 4-day adult
18
Paraquat 10 mM 48 hrs, 4-day adult
30
Rotenone 2 μg 12 hrs, larvae L3
32
Rotenone 8 μg 12 hrs, larvae L3
26
Expression Level Scale
Very low
Low
Moderate
Moderately high
log, scaled to High expression
Treatment
Expression Level
extended cold, 4-day adult
22
cold shock, 4-day adult
18
heat shock, 4-day adult
22
Cadmium 50 mM 6 hrs, larvae L3
25
Cadmium 50 mM 12 hrs, larvae L3
30
Cadmium 50 mM 48 hrs, 4-day adult
30
Cadmium 100 mM 48 hrs, 4-day adult
42
Copper 0.5 mM 12 hrs, larvae L3
21
Copper 15 mM 48 hrs, 4-day adult
26
Zinc 5 mM 12 hrs, larvae L3
26
Zinc 4.5 mM 48 hrs, 4-day adult
29
Ethanol 2.5% 3 hrs, larvae L3
23
Ethanol 5% 3 hrs, larvae L3
28
Ethanol 10% 3 hrs, larvae L3
29
Caffeine 1.5 mg/ml 4 hrs, larvae L3
25
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
22
Caffeine 25 mg/ml 48 hrs, 4-day adult
18
Paraquat 5 mM 48 hrs, 4-day adult
18
Paraquat 10 mM 48 hrs, 4-day adult
30
Rotenone 2 μg 12 hrs, larvae L3
32
Rotenone 8 μg 12 hrs, larvae L3
26
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
log, scaled to Extremely high expression
Treatment
Expression Level
extended cold, 4-day adult
22
cold shock, 4-day adult
18
heat shock, 4-day adult
22
Cadmium 50 mM 6 hrs, larvae L3
25
Cadmium 50 mM 12 hrs, larvae L3
30
Cadmium 50 mM 48 hrs, 4-day adult
30
Cadmium 100 mM 48 hrs, 4-day adult
42
Copper 0.5 mM 12 hrs, larvae L3
21
Copper 15 mM 48 hrs, 4-day adult
26
Zinc 5 mM 12 hrs, larvae L3
26
Zinc 4.5 mM 48 hrs, 4-day adult
29
Ethanol 2.5% 3 hrs, larvae L3
23
Ethanol 5% 3 hrs, larvae L3
28
Ethanol 10% 3 hrs, larvae L3
29
Caffeine 1.5 mg/ml 4 hrs, larvae L3
25
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
22
Caffeine 25 mg/ml 48 hrs, 4-day adult
18
Paraquat 5 mM 48 hrs, 4-day adult
18
Paraquat 10 mM 48 hrs, 4-day adult
30
Rotenone 2 μg 12 hrs, larvae L3
32
Rotenone 8 μg 12 hrs, larvae L3
26
Expression Level Scale
Very low
Low
Moderate
Moderately high
High
Very high
Extremely high
Heatmap
Treatment
Expression Level
extended cold, 4-day adult
cold shock, 4-day adult
heat shock, 4-day adult
Cadmium 50 mM 6 hrs, larvae L3
Cadmium 50 mM 12 hrs, larvae L3
Cadmium 50 mM 48 hrs, 4-day adult
Cadmium 100 mM 48 hrs, 4-day adult
Copper 0.5 mM 12 hrs, larvae L3
Copper 15 mM 48 hrs, 4-day adult
Zinc 5 mM 12 hrs, larvae L3
Zinc 4.5 mM 48 hrs, 4-day adult
Ethanol 2.5% 3 hrs, larvae L3
Ethanol 5% 3 hrs, larvae L3
Ethanol 10% 3 hrs, larvae L3
Caffeine 1.5 mg/ml 4 hrs, larvae L3
Caffeine 2.5 mg/ml 48 hrs, 4-day adult
Caffeine 25 mg/ml 48 hrs, 4-day adult
Paraquat 5 mM 48 hrs, 4-day adult
Paraquat 10 mM 48 hrs, 4-day adult
Rotenone 2 μg 12 hrs, larvae L3
Rotenone 8 μg 12 hrs, larvae L3
Expression Clusters
A cluster of genes with similar mRNA expression dynamics across development.
External Data & Images
Linkouts
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
Alleles & Phenotypes Summary of Allele Phenotypes Classical Alleles ( 1 ) For All Classical Alleles Show Alleles Carried on Transgenic Constructs
( 5 ) For All Alleles Carried on Transgenic
Constructs Show Aneuploid Aberrations Transgenic Constructs & Insertions
Transgenic Constructs Insertions Gene Ontology: Function, Process
& Cellular Component ( 5 unique terms )There is no information supporting a
cellular component term for this gene.
(Based on a review of available data on: 2013-03-07)
Terms Based on
Experimental Evidence ( 2 terms ) Molecular Function ( 0 terms) Biological Process inferred from mutant phenotype
inferred from mutant phenotype
Cellular Component ( 0 terms) Terms Based on Predictions or
Assertions ( 3 terms ) Molecular Function inferred from sequence or structural similarity
non-traceable author statement
Biological Process ( 0 terms) Cellular Component ( 0 terms) Sequence Ontology: Class of Gene Interactions & Pathways
Summary of Physical Interactions
protein-protein anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
anti tag coimmunoprecipitation, peptide massfingerprinting
Summary of Genetic Interactions Interacts with Please look at the allele data
for full details of the genetic interactions
External Data Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
Orthologs
OrthoDB Orthologs (132)
- based on analysis using Dmel annotation version 5.41
OrthoDB Ortholog Groups
OrthoDB orthology group searches
Drosophila inclusive ortholog search
Dipteran inclusive ortholog search
No orthologs identified
Insect inclusive ortholog search
Arthropod inclusive ortholog search
Metazoa inclusive ortholog search
Orthologs in Drosophila Species
(EOG6WDDXT )
Drosophila melanogaster
fruit fly
Drosophila pseudoobscura pseudoobscura
Y
Orthologs in non-Drosophila Dipterans (None identified)
No non-Drosophilid orthologies identified
Orthologs in non-Dipteran Insects
(EOG6FN3DT )
Apis mellifera
Western honey bee
Amel\LOC409068
Nasonia vitripennis
Parasitic wasp
Nvit\Nasvi2EG007888
Acromyrmex echinatior
Panamanian leafcutter ant
Aech\AECH16531
Atta cephalotes
Leafcutter ant
Acep\ACEP26372
Camponotus floridanus
Florida carpenter ant
Cflo\CFLO16325
Harpegnathos saltator
Jerdons jumping ant
Hsal\HSAL17905
Linepithema humile
Argentine ant
Lhum\LH20935
Pogonomyrmex barbatus
Red harvester ant
Pbar\PB13641
Solenopsis invicta
Red fire ant
Sinv\SINV10431
Acyrthosiphon pisum
Pea aphid
Acyrthosiphon pisum
Pea aphid
Pediculus humanus
Human body louse
Pediculus humanus
Human body louse
Tribolium castaneum
Red flour beetle
Tribolium castaneum
Red flour beetle
Tribolium castaneum
Red flour beetle
Orthologs in non-Insect Arthropods
(EOG61894D )
Daphnia pulex
Water flea
Y
Daphnia pulex
Water flea
Y
Daphnia pulex
Water flea
Y
Daphnia pulex
Water flea
Y
Daphnia pulex
Water flea
Y
Daphnia pulex
Water flea
Y
Daphnia pulex
Water flea
Y
Daphnia pulex
Water flea
Y
Daphnia pulex
Water flea
Y
Daphnia pulex
Water flea
Y
Daphnia pulex
Water flea
Y
Daphnia pulex
Water flea
Y
Daphnia pulex
Water flea
Y
Daphnia pulex
Water flea
Y
Ixodes scapularis
Deer tick
Y
Ixodes scapularis
Deer tick
Y
Orthologs in non-Arthropod Metazoa
(EOG6HXHV6 )
Caenorhabditis elegans
Nematode
Y
Caenorhabditis elegans
Nematode
Y
Caenorhabditis elegans
Nematode
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Strongylocentrotus purpuratus
Purple sea urchin
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Xenopus tropicalis
Western clawed frog
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Gallus gallus
Domestic chicken
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Mus musculus
House mouse
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Rattus norvegicus
Norway rat
Y
Human Orthologs (14)AAA Orthologs (11)
based on analysis using Dmel annotation version 4.3
Drosophila pseudoobscura pseudoobscura
Stocks & Reagents Stocks Listed in FlyBase ( 6 )Bloomington VDRC Genomic Clones ( 2 )Please Note FlyBase no
longer curates genomic clone accessions so this list
may not be complete
cDNA Clones ( 72 )Please Note This section lists
cDNAs and ESTs that fall within the genomic extent
of the gene model, which may include cDNAs and ESTs
of genes within introns, or of overlapping genes.
Please see
GBrowse for alignment of the cDNAs and ESTs
to the gene model.
cDNA Clones, Fully Sequenced
BDGP DGC clones Other clones cDNA Clones, End Sequenced
(ESTs) BDGP DGC clones Other clones RNAi & Array Information Linkouts
- Results from RNAi screens.
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Antibody Information
Other Information Discoverer Etymology Identification Relationship to Other Genes Source for database identity of Source for identity of: AnxB11 Anxb11
Source for identity of: Anxb11 CG9968
Source for database merge of Source for merge of: Anxb11 BcDNA:GH16395
Additional comments FlyBase curator comment: Renamed from 'Anxb11' to 'AnxB11' in order to make the nomenclature of D. melanogaster Annexins consistent with each other and with the standard Annexin nomenclature.
Source for merge of Anxb11 BcDNA:GH16395 was TrEMBL update (date:020807).
Source for identity of Anxb11 CG9968 was sequence comparison (date:000407).
Other Comments RNAi screen using dsRNA made from templates generated with primers directed against this gene causes a phenotype when assayed in S2R+ cells: cells become round and detached. Kc167 cells are unaffected.
dsRNA made from templates generated with primers directed against this gene tested in RNAi screen for effects on Kc167 and S2R+ cell morphology.
External Crossreferences & Linkouts
Sequence Crossreferences
- A searchable database of RefSeq genes.
Other Crossreferences
domains - A database of protein families, domains, and functional sites
- Patterns of gene expression in Drosophila embryogenesis
Linkouts
- A database of protein and genetic interactions
- DPiM, Drosophila Protein interaction Map
- A comprehensive database of gene and protein interactions.
- Results from RNAi screens.
- Cell culture data for RNAi and other high-throughput technologies
- Adult expression by tissue, using Affymetrix Dros2 array
- Integrated genomics database for Drosophila, Anopheles, and C.elegans
- GenomeRNAi – A database for cell-based and in vivo RNAi phenotypes and reagents
Protein-protein interactions (PPI) from both known and predicted PPI data sets.
- Data generated by the modENCODE project.
Synonyms & Secondary IDs
( 8 )Reported As Symbol Synonym Name Synonym Secondary FlyBase
IDs References ( 35 )Generate a list of List References by type
Recent research papers ( 1 )
Tjota et al., 2011, J. Cell Sci. 124(17): 2914--2926Annexin B9 binds to {beta}H-spectrin and is required for multivesicular body function in Drosophila. [FBrf0215049]